LOCUS       gnlProkkaAMEGBIBC_420   7970 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AMEGBIBC_420.
ACCESSION   gnlProkkaAMEGBIBC_420
VERSION     gnlProkkaAMEGBIBC_420
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:28:21
            Original ID  :: gnl|Prokka|AMEGBIBC_420
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7970
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7970
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1:4756]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..4756
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..7970
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7970
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(2..409)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg420_1"
                     /sec_met_domain="APE_KS2 (E-value: 2.5e-17, bitscore: 52.3,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYPLNIYITAHTLISSLGFGISENKKAIHDYRSGIRMQEAGRIS
                     DSPILAGMIDSVELEKRAKEQLEKRAKELDISSYTRLEQLFILTIQEVISQSGVNLQES
                     DCALLLSTTKGNIDLLSDQEKRTNSDKPSGSV"
     CDS             complement(394..837)
                     /locus_tag="ctg420_2"
                     /transl_table=11
                     /translation="MKRKTNQQIAALTNRTTFRVRFSEIDSMQIVWHGEYVRYFEDGRE
                     AFGKQYGLDYMSIYREGYMVPIVDLTCQFKQSLSFGEEAIIETRYIACEAAKIKFEYVI
                     YRATDQSVVATGSTIQVFLNLNKELELINPPFYLEWKKKWNIL"
     CDS             complement(834..1268)
                     /locus_tag="ctg420_3"
                     /transl_table=11
                     /translation="MNREAVIQGEGILNLIPQRPPIVMVDSFFGFEENRSYSGLTVTTD
                     NLFCEAGRLQEPGIIEHIAQSAAARIGFIYTRQGEKVPLGFIGSVDKLKIYNLPEAGMK
                     LFTEITVVQEVFDITLISAQVKAEEELIAECKMKIFIKKE"
     CDS             complement(1265..2335)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 127.6; E-value:
                     1.1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg420_4"
                     /transl_table=11
                     /translation="MQQNKYDKEPLTAVEAQRLAQEIAFGPIVFQVSRLMLKFGIFQLL
                     ADERKGMTQEEISKACGLSSYGAQVLLEASLTIGTVLLREGRYCLAKAGWFLLNDKMVR
                     VNMDFNHDVNYQGMFHLEEAITNGRPEGLKVFGEWSTIYEGLSSLPSQVQKSWFGFDHY
                     YSDCSFDEALAIVFARHPKTLLDVGGNTGRWATKCVSYDDTVEVTIMDLPQQLEMMRQQ
                     TKELPGATRIHGHGANLLDPEVPFPTGFDAIWMSQFLDCFSEEEVTSILTRAARSMSRE
                     SRLYIMETFWNRQKFDTAAYCLTQISLYFTAMANGNSKMYHSDDMQRCIEAAGLEIEEI
                     HDHLGMGHSIVQCRLK"
     CDS             complement(2322..3257)
                     /locus_tag="ctg420_5"
                     /transl_table=11
                     /translation="MSTWKGKTRGGTFGYLFFIYLIKYLGITAAYLFLSLVVLYFIPFA
                     PKATKSTWFYARNILKYNRIHSLKMLLLNYYRLGQILIDKVAIGNGKVNQYQFKFEQYP
                     EFLQLLNSEQGVIMIGAHVGNWEIGVPFFDDYGKKINIVMYDAEHRRIKEILEKNGQDK
                     EFKIIPVNEDNLTHVFRITEAINQKEYVCFQGDRYLNKEKLLPGILLGQKAPFPAGPFL
                     LASRMKVPVVFYFAMREPGRTYRFHFIIAEPVVRTKEKKAEMALLEQYTVALEQILKRY
                     PEQWFNYYPFWEPAGKQSPDLKEKQKDATE"
     CDS             complement(3260..3511)
                     /NRPS_PKS="Domain: PP-binding (7-75). E-value: 3.8e-14.
                     Score: 44.9. Matches aSDomain:
                     nrpspksdomains_ctg420_6_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg420_6"
                     /sec_met_domain="PP-binding (E-value: 6.7e-15, bitscore:
                     44.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNEEIIEKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDM
                     VVLVEKNFGFNVTGQDFAGIKTFQDFYDLVITRMQEAK"
     aSDomain        complement(3287..3490)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg420_6_PP-binding.1"
                     /evalue="3.80E-14"
                     /label="ctg420_6_PP-binding.1"
                     /locus_tag="ctg420_6"
                     /protein_end="75"
                     /protein_start="7"
                     /score="44.9"
                     /tool="antismash"
                     /translation="EKIRTTLAEEFEVDIDVIQPDAPLMETLELDSLDLVDMVVLVEKN
                     FGFNVTGQDFAGIKTFQDFYDLV"
     CDS             complement(3533..4756)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (65-405). E-value:
                     1.8e-53. Score: 173.8. Matches aSDomain:
                     nrpspksdomains_ctg420_7_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 296.3; E-value:
                     6.6e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg420_7"
                     /sec_met_domain="APE_KS1 (E-value: 1.5e-159, bitscore:
                     520.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGIDEAFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDK
                     RRDGLIPSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQM
                     AIKDAGIALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAG
                     ASEVIYSTLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNST
                     LIIRQIKE"
     aSDomain        complement(3542..4561)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg420_7_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-53"
                     /label="ctg420_7_PKS_KS.1"
                     /locus_tag="ctg420_7"
                     /protein_end="405"
                     /protein_start="65"
                     /score="173.8"
                     /tool="antismash"
                     /translation="RLCLPEQGEYAYLATLEAFRNAGIDEAFLEANEVGILYGNDSSAA
                     PVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHAI
                     GMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAEPEKASKPFDKRRDGLI
                     PSGGAASLVLESYESAVKRGAPILAEVIGYGFSSNGDHISVPNVDGPKRSLQMAIKDAG
                     IALEQISYINAHATSTPVGDLNEAKAIAEVFEGHHPYVTSTKSMTGHEMWMAGASEVIY
                     STLMMNNGFIAPNLNFEEPDEASAQLNIPTQRVNLEFDTFLSNSFGFGGTNSTLIIRQI
                     "
     CDS             complement(4783..5511)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 1.3e-16. Score:
                     52.9. Matches aSDomain: nrpspksdomains_ctg420_8_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     212.9; E-value: 8.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg420_8"
                     /sec_met_domain="adh_short (E-value: 2.8e-36, bitscore:
                     114.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQL
                     VQEKGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WNKVLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTVEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        complement(5005..5502)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg420_8_PKS_KR.1"
                     /evalue="1.30E-16"
                     /label="ctg420_8_PKS_KR.1"
                     /locus_tag="ctg420_8"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQSNDAEAEKTLQLVQE
                     KGSNGEIMKFDVTDPAAIALALNNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWNK
                     VLDISLNGFFYVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       complement(5437..5499)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg420_8_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg420_8"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             complement(5513..7036)
                     /locus_tag="ctg420_9"
                     /transl_table=11
                     /translation="MIADKSINLDTLYKVLFDNEKLELSKECIRKVEESFDFLQSFSSD
                     KIIYGINTGFGPMAQYRIEDQSLIELQYNIIRSHSTGAGKPLPELYVKAAMIARLYTFL
                     QGKSGVHMELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVFYQGK
                     LRDAATVLEENGLQPFSMRIREGLSVTNGTSVMTGIGIVNLIYAKKLLRWSVAASVMMN
                     EIAASYDDFMAQALNEAKHHKGQQETAAMMREWVAGSKCVLQRENELYNQVHKEKIFEH
                     KVQPYYSLRCVPQILGPIYDELKNAEEVLINEINSACDNPIVDPDTQNIYHGGNFHGDY
                     ISFEMDKLKIAVTKLTMLCERQINYLFHDRINGILPPFVNLGVLGLNYGLQASQFTATS
                     TTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKTVIENSYQVMAIQFMGMAQAI
                     DYLKIQDRLSPKSRQVYEEIRSFFPVFTNDTPKYKEIERMMNYLKKENK"
     CDS             complement(7196..7627)
                     /locus_tag="ctg420_10"
                     /transl_table=11
                     /translation="MEEIVFHHTLPIQLRFNDVDKFGHVNNTVYFSFYDLGKTEYFASV
                     CPGVDWEKIGIVVVHIEADFVKQIFASDHIAVQTAVSKIGTKSFHLIQRVIDTETNEVK
                     CICKSVMVTFDLERHESMPLTEEWIEAICKYEERDLQKA"
ORIGIN
        1 gtacagaacc gcttggcttg tccgaattag ttcttttttc ttgatcgctc aataaatcaa
       61 tatttccctt cgtagtagag agcaacaaag cacagtccga ttcttgcaga ttcactcccg
      121 attgggaaat cacttcctga atagtcaata taaacagttg ctccaaccgg gtataagagg
      181 aaatatccag ctcctttgcc cgcttttcta attgttcttt agctctcttt tccaactcga
      241 cagaatcaat catccctgcc agaatcggac tgtcagaaat ccgtccggct tcctgcatac
      301 gaatcccgct tcgatagtca tggattgctt ttttgttttc cgaaataccg aaacctaacg
      361 aactaatcag cgtatgggct gtgatgtata tatttaaagg atattccatt tctttttcca
      421 ttccagataa aacggaggat tgataagctc cagttcttta ttcaggttca ggaacacttg
      481 tatggtgctt ccggtggcca ctacactttg gtcggtagcc cggtagataa cgtattcgaa
      541 ttttatcttg gctgcctcac aggcaatata gcgtgtttcg ataatcgctt cttcaccaaa
      601 ggacaatgat tgcttgaact ggcaggttaa atctacgatg ggaaccatgt agccttcccg
      661 gtaaatgctc atataatcca aaccatactg tttgccgaaa gcttcccgcc catcttcaaa
      721 gtagcgcacg tactcgccat gccatacaat ctgcatggag tctatttcgc tgaaccgtac
      781 tctgaaagta gtccggttag tcaaagctgc aatctgttga tttgttttcc gtttcattct
      841 tttttgataa atattttcat cttacattca gcaatcagct cttcttccgc tttcacttgt
      901 gccgaaatta gcgtaatatc gaatacctct tgtacgacgg taatctctgt aaataatttc
      961 attccggctt ccggcaagtt gtagatttta agtttgtcta ccgaaccgat aaaacctaac
     1021 ggaacttttt caccctgccg ggtataaata aacccgatac gtgcagccgc tgattgtgcg
     1081 atatgctcga taattcccgg ctcttgcagt ctgcctgcct cacaaaataa attgtcggta
     1141 gtgacagtca gtccggaata tgaacggttt tcttcaaatc cgaagaaact gtccaccata
     1201 acgattggcg gacgctgtgg aatcaggttg agtattcctt ctccttgtat gacggcttct
     1261 ctgttcattt caatctgcat tgtacgatgc tgtgtcccat tcctaaatgg tcatgtatct
     1321 cttcgatttc caatcctgct gcttcgatgc atcgttgcat atcatccgaa tgatacatct
     1381 tgctgtttcc gtttgccatc gctgtaaaat agagactgat ttgtgtcagg caataagcgg
     1441 ctgtatcaaa tttctgccgg ttccagaaag tctccataat atacaggcgg ctctcccggc
     1501 tcatggaacg ggctgcacgg gtcaatatgc tggtaacttc ttcttccgag aaacaatcga
     1561 ggaactggct catccaaata gcatcgaacc ctgtcgggaa aggcacttcc ggatcaagca
     1621 gattggcacc atgaccgtgg atacgtgtag ctccgggcag ctctttggtt tgttgacgca
     1681 tcatctccaa ttgttgcgga aggtccatga tggttacttc cactgtgtcg tcgtagctta
     1741 cgcatttggt cgcccaacgg ccggtattgc ctcccacatc caataaagtc ttgggatgac
     1801 gggcgaagac aattgccagt gcttcatcga acgaacaatc cgagtaataa tgatcgaaac
     1861 cgaaccagct cttttgtact tgtgaaggca gacttgacaa cccttcatag atagtactcc
     1921 attcaccgaa tactttcagt ccttcaggac gtccgttggt gatggcttct tccagatgaa
     1981 acattccctg atagttaaca tcatggttga agtccatatt gacacgtacc attttgtcat
     2041 tgagcagaaa ccagccggct ttcgcaaggc agtatcgccc ttcacgcaac aatacggtgc
     2101 cgatagtcaa tgatgcctcc aacaatactt gtgcgccata agaggacagc ccacaagctt
     2161 tgctgatttc ttcttgcgtc atacctttgc gctcgtcggc caataactgg aaaattccga
     2221 atttaagcat aaggcgtgat acctgaaaaa caataggccc aaaagctatt tcttgtgcca
     2281 ggcgttgtgc ctctaccgct gtcaacggct ctttgtcata tttattctgt tgcatctttt
     2341 tgtttctctt ttaaatccgg tgactgcttt ccggcaggtt cccagaatgg ataataattg
     2401 aaccattgtt ccggatagcg ttttagtatc tgttccaaag caacagtata ttgttcgagc
     2461 agagccatct ccgctttctt ttcttttgtt cgtactaccg gttccgctat tataaaatga
     2521 aaacggtaag ttcttcccgg ttccctcatt gcaaagtaga ataccaccgg aactttcatt
     2581 cgcgaagcga gcaggaaagg accggcagga aaaggagctt tctgtcccag taaaattcct
     2641 ggcagaagtt tctctttgtt cagataacgg tcgccttgga aacatacata ttctttttgg
     2701 ttgatcgcct cggttatgcg gaaaacgtgt gtcaggttgt cttcattgac agggataatc
     2761 ttaaactcct tgtcctgacc gtttttctcc aggatctctt tgattctacg atgttcggca
     2821 tcgtacatca cgatattgat tttctttccg taatcatcaa agaaaggaac gcctatttcc
     2881 cagtttccca catgggcgcc aatcataatc actccctgtt cactgttcag cagttgcaga
     2941 aactccggat actgctcgaa tttgaactga tattgattta cttttccatt accgatggct
     3001 accttgtcaa tcaggatttg tcctaatcgg taatagttga gtagtaacat tttcaaagaa
     3061 tgtatcctat tgtatttcag aatgttacgg gcataaaacc aggtgctttt ggttgctttc
     3121 ggagcaaacg gtatgaagta gagcactacc aggcttagaa aaagataagc ggcagtaatg
     3181 cccagatact taatcaggta aataaagaat aagtatccga acgttcctcc ccgggttttg
     3241 cctttccacg tcgacatatt tacttggctt cctgcatacg ggtgataacg agatcgtaga
     3301 agtcctggaa ggttttgata cctgcaaagt cttgtccggt tacattgaaa ccgaaattct
     3361 tttctaccaa taccaccatg tcgaccaagt ccaaactgtc cagttcaaga gtttccatta
     3421 acggcgcatc cggctggatg acgtcgatgt ctacttcaaa ctcttctgcc agagttgttc
     3481 ttattttctc aatgatttct tcatttgtca tatatctgtt ttctttagta atttattctt
     3541 tgatttggcg tataatcagg gtggaattgg ttcctccgaa tccaaacgaa ttggaaagga
     3601 acgtgtcaaa ttccagattt acccgttggg taggtatatt caactgtgcg gaagcctcat
     3661 ccggttcctc gaaattgagg ttgggagcga tgaaaccgtt gttcatcatg agggtggagt
     3721 aaatcacttc actggcacct gccatccaca tttcatgtcc ggtcatagac ttcgtggaag
     3781 tgacatacgg gtgatgtcct tcaaatactt ccgcaatggc tttcgcttcg ttcaggtcgc
     3841 ctaccggagt ggaagtggcg tgtgcattga tataactgat ttgttcgagt gcaatacccg
     3901 catctttgat ggccatctga agagaacgtt tcggaccgtc cacattcggt acggagatat
     3961 gatctccatt ggaagagaaa ccgtaaccga taacttcggc caaaatggga gctcctcttt
     4021 ttactgccga ttcatagctc tctaatacca gactggcggc tcctccactc ggaatcagtc
     4081 cgtcacgtcg tttatcaaaa ggtttggagg ctttctcggg ctctgcttcc tgggtggaaa
     4141 atgcgcttag cccgtcgaaa ctgccgaccg cataaggatt tacttcttgt gcgccaccgc
     4201 aaagaataca atcctgcaat cctgatttaa tgagcagata acccatgcca atagcatgag
     4261 aaccacttgc gcaggctccg gcaatggtga agttaactcc tctaagcttg aagataaccg
     4321 acaggttcat tgtcacggta gaattcatcg actggaaaat agaaccggaa cctaccaacg
     4381 ctgtattttt cttttcacga atgatgtcca ctgcgttgat aacaggggcg gcactactat
     4441 cattgccata caagataccc acttcattag cttcgagaaa agcctcgtca ataccggcgt
     4501 tgcggaaagc ctccaaagta gcgagataag catattctcc ctgttccggc aggcagagac
     4561 gtttacgacg atctaatagt ttcttcaagt cgggacgttc caatatgccc gttaatgcag
     4621 aaaaatagcc cagctctttc cgtaccggat ctatgccaat ccccgatttc ccattgtata
     4681 gtgagtcttt tacttcatcc aggttcttgc cgatgcaaga gtaaattccc attcccgtga
     4741 taacaactct tttcattatt ttgtctattc tatgcttttg ttttaagtat atagtcctcc
     4801 gttgatggaa atcacctctc ctgtgatata ggatgaggcc ggagatgcca gaaaaccgac
     4861 gagatcggca acctcttcca cagtaccgaa acgtcctgca ggaatgtgtt ttttccattc
     4921 gttctcatca atcccttccg tcatatccgt gcggataaat cctggggcta cagcgttgac
     4981 tgttaccttt ttcttggcga cttcttgtgc cagtgctttg gtagcggcta ttacgccacc
     5041 tttggctgcg gaatagttag cttgtccggg cattccctga atacctgaca aggatacgat
     5101 attgacaata cgtccataac gcttgaccag catattcttc aataaaggct gtgtcacata
     5161 aaagaatccg ttcagactga tatcgagcac tttgttccat tcttctcctg tcatccagag
     5221 catcaggttg tctttacgga tgcccgcatt gttgatcagt acttcgatgt attcgtcagg
     5281 atgttgtgac gcccagttgt tcaaggcaag ggcaatagcg gcagggtctg tcacatcgaa
     5341 cttcatgatt tctccgttac ttcctttttc ctgcactaac tgcaacgttt tttctgcttc
     5401 tgcgtcgtta ctctgataat taatcagtat aaagtagccc atttccgcca gtttgcaact
     5461 gacagcacgg ccgatacctc gacttcctcc ggttactaat gcgtatttca ttttatttat
     5521 tttctttttt gagatagttc atcattcttt ctatctcttt gtatttaggt gtgtcattgg
     5581 taaatacagg gaagaagcta cgtatctctt catacacctg ccggcttttg ggacttagac
     5641 gatcctgtat tttcaggtag tcgatggctt gtgccattcc cataaattga atagccatca
     5701 cctgataaga attctctatg actgtttttg ctaatagagc cgagttggtt cccatgctga
     5761 caatatcctg attatcgttg ttgttaggaa tactgtgcac atacatcgga ttcgacaatg
     5821 tctgacattc ggcggtagtg gacgttgctg tgaattgcga agcctgcaaa ccgtagttca
     5881 atccaagcac tcccaagttt acaaaaggag gcaggatgcc attgatacgg tcgtggaaca
     5941 gataattgat ctgtctttcg caaagcatgg tcagtttggt tacggcgatt ttcagtttat
     6001 ccatttcgaa agagatgtaa tctccgtgga agttaccgcc atgataaata ttttgtgtgt
     6061 ccggatcgac aatcggattg tcgcaggcgg aatttatttc gttaatcaat acttcttccg
     6121 cattcttcag ctcatcatag atgggaccga ggatttgcgg aacacatcgc aaggaataat
     6181 agggctgtac tttgtgctcg aagatttttt ctttgtgcac ctggttgtat agctcattct
     6241 ctctttgaag tacacatttg ctgcccgcga cccattctct catcatagcg gctgtctctt
     6301 gttgcccttt gtgatgcttg gcctcgttta atgcctgtgc catgaaatca tcataagagg
     6361 cggcaatctc attcatcatg acagaagcgg ctaccgacca acggagcagc tttttggcat
     6421 aaatcagatt gacgataccg attcctgtca tcacagaagt accgtttgtg acggataatc
     6481 cttcgcggat gcgcattgaa aaaggttgca gaccgttttc ctcaagcaca gtagcggcat
     6541 cacgcaattt cccctgataa aaaacttccc cttctcctat taatgtcagg gcaatatggg
     6601 ccagttgcac gagatcgccg ctggcaccta cacttccatg ttcgggtatg aacggataaa
     6661 ttccacggtt gataaattca cagagaagag ataccagctc catgtgtact cctgatttcc
     6721 cctgtagaaa agtgtacagg cgggcaatca tagctgcttt tacataaagt tcgggaagtg
     6781 gtttgccggc accggtggaa tggcttcgaa tgatattgta ctgaagctcg atcagtgact
     6841 gatcttctat ccggtattgt gccattgggc cgaaccccgt attgatacca taaataatct
     6901 tatcgctgga aaaagattgt aggaaatcga agctttcctc tacttttcgg atgcattctt
     6961 tagagagttc cagcttctca ttatcaaaca atactttata aagggtatct aaatttatac
     7021 ttttgtcagc tatcattttc tgtactagat attttatgcc ttattaatta aggtacaaaa
     7081 ataggcaatt tctgttatat agcggacatg aatcagaata aaactttttc cggagaattg
     7141 gttttgcttg ttttgtttct cattcgtgag ggggcttttt caaaaaaaaa actatctatg
     7201 ctttttgcaa gtcccgttct tcatatttgc agatcgcctc tatccattct tctgtcagtg
     7261 gcatggattc atgtctttca agatcgaaag taaccataac agacttgcag atacatttta
     7321 cttcattcgt ttctgtgtcg ataacccgct ggatcaggtg aaagcttttg gtgcctatct
     7381 tagaaacagc agtctgtacg gcgatatgat cggatgcgaa tatctgtttg acgaaatccg
     7441 cttcgatgtg gacaacgaca atcccgatct tttcccaatc tactccgggg catactgaag
     7501 cgaagtattc agtctttcct aagtcgtaaa aggagaagta aactgtgttg ttgacgtgac
     7561 caaatttgtc tacatcattg aatcgcaatt ggataggtaa tgtgtgatga aatacgattt
     7621 cttccattgt tttctcttaa acgttttaaa ttcgacacaa aaatggcact tttgctttct
     7681 tgcttgaaat tgaggcaaag atagagattt ctaatgattc tgctttcgga gataaggaag
     7741 attttcgtta ataatcgttt aaaacgaagt tttgggatgt ttgttctgtt agggaaacac
     7801 gcttgtaata atgtaatagt taaattgttg tctgccaata gttgatttta aagggtgatt
     7861 taaaaacgtc aggatagatt tcactaaatg gaataaatgt gttatttttg catcttgttc
     7921 ttaacggaaa ttaatcaaga aatgatagaa gatattaaaa aagcctgtca
//
