LOCUS       c00627_gnlPro..         4413 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AMEGBIBC_627.
ACCESSION   c00627_gnlPro..
VERSION     c00627_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 09:39:48
            Original ID  :: gnl|Prokka|AMEGBIBC_627
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4413
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..255
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg627_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-27, bitscore:
                     84.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GGTSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTD
                     EELAARPMTPVTRDRYVPKSLKAYASMVSSADKGAVRII"
     protocluster    1..4413
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4411]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4411
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4413
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4413
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             380..2074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg627_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.5e-48, bitscore:
                     150.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRAFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             2132..2689
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg627_3"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             2695..3438
                     /locus_tag="ctg627_4"
                     /transl_table=11
                     /translation="MNEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             3506..4411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg627_5"
                     /sec_met_domain="IlvN (E-value: 4.3e-47, bitscore: 148.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.8e-34, bitscore: 107.5,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACERGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGN"
ORIGIN
        1 ggtggaactt ccggattgag tatcggacat atttctcctg aagcggcagc tggaggcaat
       61 atcggaaaaa ttgtagacgg agacattatc gaaatcgata ttccggcccg gaagattaac
      121 gtgcgactga cggatgaaga actggcggcc cgtccgatga ctcctgttac tcgtgaccgt
      181 tatgtaccga agagcctgaa ggcgtatgcc agcatggtaa gctctgccga taagggagca
      241 gtgagaatta tataatatag ttggtgatag ttgataggta atagttagct gcgcagcact
      301 tagcgcaatg attgtaaacc attcattttc aactgtcatt tctcaactat catttatcat
      361 ttatcaacta tcaactaata tgaaagattt aataacaggt gcagaggctt tgatgcgctc
      421 cttggaacat cagggagtga ctaccatctt tggttacccc ggtggttcta ttatgccggt
      481 attcgatgcc ttgtacgatc atcaaaatat attgaatcat atcttggttc gtcacgaaca
      541 gggagctgcc catgccgcac agggttatgc ccgtgtatcg ggtgatgtag gtgtttgcct
      601 ggtgacgagc ggtcccggag caaccaatac ggtaacaggc attgcggatg cgatgatcga
      661 tagtacgcct atcgtggtga ttgccggaca ggtaggaaca ggctttcttg ggacggatgc
      721 ttttcaggaa gttgacttgg taggtatcac ccagccaatc actaaatgga gttatcagat
      781 tcgccgtgcg gaagatgtag cctgggcggt agcacgtgcg ttttacattg cccgtagtgg
      841 tcgtccgggt ccggtggtat tggactttgc caaaaatgcg caagtagaga aaacgaaata
      901 cgaaccgacg aaagtcgatt ttatccgtag ttatgttcct gttcccgata cggacgagga
      961 gactgtacag gctgctgccg aactgattaa taacgctgaa cgtccgcttg tattggttgg
     1021 acaaggtgtt gaactgggaa atgcacagag cgaattgcgc gagtttatcg aaaaagcgga
     1081 tatgcctgcg ggttgtacgc tgctcggact ttcggctttg ccgacagaac atccgttgaa
     1141 taaaggtatg ttgggtatgc acggcaatct gggaccgaat atcaatacca ataaatgcga
     1201 tgtgctgatt gctgttggta tgcgttttga cgaccgtgtg accggtaatt tggctactta
     1261 tgccaaacag gcaaaagtga ttcattttga tatcgatcct gcggaagtta ataagaatgt
     1321 aaaggtagat gtagctgtat tgggagattg caaggaaaca ctggcttctg tgacgaaact
     1381 tctgaaaaag aacactcata ccgaatggat tgatagcttc aaagaatatg agaaagtaga
     1441 ggaggaaaaa gtaatccgtc ccgaacttca tcctgccaca aactctttga gtatggggga
     1501 agtggtacgt gcggtaagtg atgctactca ccatgaagct gttttggtaa cagatgtagg
     1561 tcaaaatcag atgatatctg cacgctactt taaatatacg aaagaacgca gtatcattac
     1621 ttccggagga cttggaacaa tgggcttcgg gcttcccgca gctatcgggg caactttcgg
     1681 agcaccggaa cgcaccgtat gcgtatttat gggagatggc ggactgcaaa tgaatattca
     1741 ggaactgggt acgattatgg agcagaaggc tccggtgaag attatctgcc tgaacaataa
     1801 ttacctagga aacgtacgtc agtggcaagc tatgtttttc aaccgtcgct attcgtttac
     1861 cccgatgttg aatccggatt atatgaaagt ggcctcggct tatgatattc cttccaagcg
     1921 tgctttcact cgtgaagaac tgaaggaagc tattgctgaa atgctggcaa cggacggtcc
     1981 gttcctgctc gaagcttgcg tggtggaaga aggcaatgtt ttgccgatga ctcctccagg
     2041 tggttcggta aaccagatgt tgctggagtg ctaggagaag ttgagagttg agaatggaga
     2101 gttgagggtt cgcatttaaa aaattagagt tatgagtgat aaaacgttat atacaatcat
     2161 tgttcattcg gagaatatag ccgggttgct gaatcaggta actgctgtat ttacccgtcg
     2221 gcaaataaat attgagagtc tgaatgtatc tgcttcttct attaaaggtg tacataagta
     2281 tacaataaca gcctggactg ataaggacat cattgagaag gtagtgaaac agatcgaaaa
     2341 gaagatcgac gtgattcagg cacattattt cacagaggat gaaatttatt tccacgagat
     2401 tgcattatat aaggtgtcta ctcctgcttt tcaggagaat ccggaagcat ccaagctgat
     2461 ccgtagatac aatgcacgta tagtggaagt caatccggta ttttccattg tcgagaaaaa
     2521 tggaatgagc gaagatataa cttcgctcta tggtgaactg aaggctttga attgtgtttt
     2581 gcagtttgtt cgttcgggac gtgtagcgat tactaccagc tgctttgaac gggtgaatga
     2641 gtttctcgat ggacgggaag ctatgtataa ccaaagtaaa aaccaataag aataatgaat
     2701 gaagaaaata gaatagggac ttatcagttt gtggcagaac cgttccatgt tgacttcaac
     2761 ggacgtttga ctatgggggt actgggaaat catctgctga attgtgcagg ttttcacgcc
     2821 aatgaccgtg gttttggtat tgcaacgctg aatgaggaca attatacatg ggtgctttca
     2881 cgtctggcta ttgagttgga tgaaatgcct tatcagtatg agaatttctc ggttcagacg
     2941 tgggtggaaa atgtctaccg cttgtttacg gaccgtaatt ttgctattat tgataaggat
     3001 gggaagaaga ttggctacgc acgttccgta tgggcaatga ttaatcttaa tacccgcaag
     3061 cctgccgact tgttgacttt gcatggggga agtatcgtag actatgtctg tgatgagcct
     3121 tgcccgattg aaaagccttc acgcatcaaa gtgacaagcg atcagccgat agctaccctg
     3181 acggcaaaat acagtgatat agatatcaac ggtcatgtaa acagcatccg ttacatcgag
     3241 catatccttg atttgttccc gattgaattg tataagacca aacgtatccg tcgttttgaa
     3301 atggcgtatg tggcggaaag ctattttggt gatgaactct ctttcttctg cgatgaagtg
     3361 aatgcaaacg agtttcacgt agaagtgaag aagaatggca acgaagttgt ttgccgctcg
     3421 aaagtgatat ttgaataaat gtgagaatat aaaatcaatt aataacagat ggcgtaagtc
     3481 atcaaaaact aaaaacaaaa agaaaatggc acagttgaat tttggaggta ctactgaaac
     3541 tgtagtaatc cgtgacgaat ttccattgga aaaagctcgt gaagtattga aaaatgaaac
     3601 aatcgctgta atcggttatg gcgtacaggg tcctggacag gcactgaact tgcgtgataa
     3661 cggtttcaat gtaatcgttg gtcaacgtga aggaaaaaca tacgataagg cagtagcaga
     3721 cggatgggtt ccgggtgaaa ctttgttcgg tatcgaagaa gcttgtgaga gaggtactat
     3781 tgtaatgtgt ctgttgtctg acgcagcagt aatgtcagta tggcctacta tcaagcctta
     3841 cctgactgct ggaaaagctc tttatttctc acacggtttt gctatcactt ggaacgaccg
     3901 tacaggtgta gttcctcctg ctgatatcga cgttatcatg gttgctccta aaggttcggg
     3961 tacatctttg cgtactatgt tcctcgaagg acgcggcttg aactcttctt atgctatcta
     4021 tcaggatgct acaggcaagg cttacgaaag aaccatcgca ctgggtattg gtatcggttc
     4081 cggttatctg ttcgaaacaa ctttccaacg tgaggctact tctgacttga caggtgaacg
     4141 tggttcattg atgggtgcta tccaaggttt gttgctggca cagtacgaag tattgcgtga
     4201 aaacggtcat actccttctg aagcattcaa tgaaacagtg gaagaactga cacagtcgtt
     4261 gatgccgttg ttcgcaaaga acggtatgga ctggatgtac gctaactgct ctactactgc
     4321 tcaacgtggt gctctcgatt ggatgggccc attccacgat gctatcaaac cggtagttga
     4381 aaagttgtat aacagtgtga agactggtaa cga
//
