LOCUS       c00407_gnlPro..        16638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCHAJLJL_407.
ACCESSION   c00407_gnlPro..
VERSION     c00407_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:29:50
            Original ID  :: gnl|Prokka|LCHAJLJL_407
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16638
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16638
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9891:13449](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9892..13449)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16638
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16638
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             233..1459
                     /locus_tag="ctg407_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1792..4545
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg407_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4573..4905
                     /locus_tag="ctg407_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4868..6154)
                     /locus_tag="ctg407_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFCKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6627..7853
                     /locus_tag="ctg407_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7850..8680
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg407_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8708..9568
                     /locus_tag="ctg407_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9579..9767)
                     /locus_tag="ctg407_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9892..13449)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg407_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13483..14688)
                     /locus_tag="ctg407_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14868..16022
                     /locus_tag="ctg407_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 agttagttca ctgcaactct acttttcaaa tatacactta tattttgttg tgatatttaa
       61 tactgcaaat gtaaatgtgt caaaagcaac taaactctcc tccttcctga aggaggggaa
      121 tttagttgct tttgacacat cttcttttct gtttcttatt tcagtaaatg tcccccttcc
      181 ctgtgttttg atttactact taatctgtta attattagaa tgataataac agatgttctt
      241 ttttctaatt gtccccctct ttcttgcctt gttttataag ccgattgcct atctttgcgg
      301 caggttttta aataataaat caaaaagaga aaactacttt atgaaacaca tttcgaactt
      361 cctcagatca aaaagctgga acgtattttt gtttttatat cttgctcttc ctttgtttgc
      421 gcaaaaggaa tataagatcg atcaggtatc tgttgttaat gtaggcgatg gcagactgtt
      481 gtttcaggaa ctgaaaacgg aaaaagcatt gaatggcgaa catcgcatca tagatggtta
      541 tcattccgcc tatgtgctgg catcttttaa agatggtttt tatgatggcg gatacaaaga
      601 atatgtggac aatatattaa taacggaagg aagttataaa gaagggcgga aggatggcct
      661 cttcaagatt aactccaagt ttgacggtaa gctgaaagaa gaaaagtcct ataaggaagg
      721 taagctggac ggtacgagca aaagttactt tactaccgga aaagtggaaa gtgaaagaaa
      781 cttccggatg gggaaagagc acgggaagca actgtcgtac gaatctgacg gtactttgcg
      841 gaaagagcat aattacaagg acgggaagca ggtaggcaaa cagtatactt ttctgaaagg
      901 tacatatgat ttgtatgaga ccgtttattt caatgaagaa ggttttcagg acggtgaata
      961 ttcgtccgtg tttacgtttg gctcgccacg tatactgggt agttataaga atggaaagaa
     1021 gaatggtcgt tggactactt ttgctgaaag cggagatacg ctgatgattg aaacctatct
     1081 ggatggaaaa gaagatggac tccatgtctc atttgccaac ggaagtgggg taaggcagaa
     1141 agaatattat atgaagaacg atcgtaaaga cggtttatac cgtgaatata atttggaaaa
     1201 tggtgaattg agatatgaag ctacctatca ggccggcaga ttgcatggca aggaacgacg
     1261 gctgatagtg agcaaccgct ttgattattg ggaaacttct acctatgtga acggaaggca
     1321 gaacggaccg ttcgaagctc gttatgtaaa gaatgaccag cttcgtgaat gtggggaata
     1381 taagaatggt caccgtgtag gacgatggaa acgctacact attgatggta aactggaaaa
     1441 ggaatgggat gaaaactaac cggtagatga aaggtcagag cataaaaaaa ggagcaacgc
     1501 cttgctccaa cctttgttaa ccttaaatct aatactatga aaaacacagt gcaaagatac
     1561 ggacttctgt gaaatctgca aattatccaa gtaaaacgct atgttttata acattgatta
     1621 agtgtttgtt ttacgcttta tacttttgtt aatactttcc gatggtctga aagaggactg
     1681 ctttccttct ttttagaata ataaatagct gaagttagag aactttacag tattatttct
     1741 tatttttgtt cttaattgga ttacagaaag aactatgaaa tgatgagatg gatgaagacg
     1801 atgagatatc tgaagtggat gctggtgctg tttggtttaa tcgggatgac ggcttgccgg
     1861 caggatacac cccgttttcg tattggggtg gctcaatgca gcgatgattc atggcgacat
     1921 aagatgaatg atgagattct tcgggaagcg atgttttata atggtgtttc ggtggaaatc
     1981 cgttcggcag gggatgataa cagtaagcag gcggaagatg tccattattt tatggacgaa
     2041 ggagtcgatc tgctgattat ttccgctaac gaagctgctc ctatgactcc gattgtagaa
     2101 gaagcttatc agaaaggcat ccccgttatt cttgtagacc ggaagattct ttcggataaa
     2161 tatactgcct atatcggagc cgataattat gaaatcggtc gttcggtagg aaactatatt
     2221 gcctccagtc tgaaagggaa gggaaatata gtagaactga caggattgag cggttcgact
     2281 cctgcaatgg aacggcatca gggatttatg gctgccatca gtaaattccc ggatataaag
     2341 ctgattgata aagcggatgc tgcgtgggaa cgtggtccgg cagagataga aatggatagt
     2401 atgcttcgga ggcatcctaa gattgatgct gtgtatgccc ataatgaccg tatcgctccg
     2461 ggtgcctatc aggcagcaaa gatggcaggg cgggagaagg aaatgatttt tgtcggcata
     2521 gatgccttgc cgggtaaggg aaacggactg gaactggtac tggacagtgt gctggatgcc
     2581 acctttatct atccgaccaa tggcgataag gtactgcaac tggctatgga cattctggag
     2641 aagaaaccct atcccaaaga aacggtgatg aataccgctg ttgtggaccg taccaacgca
     2701 cacgtcatgc agttgcagac cacacacatt tccgaactcg acaaaaagat tgaaacgctc
     2761 aacggacgta tcggtggcta tctctctcag gtagctacac aacaggtcgt tttatacggc
     2821 agtctgatta tccttttatt ggtagccggc ttattattgg tcgtttataa atcactccgc
     2881 tctaagaatc gcttgaataa agagcttttt aagcagaagc agcaattgga agagcagcgt
     2941 gacaaactgg aagaacagcg tgaccaattg atacagctct ctcatcaact ggaagaagct
     3001 acccatgcca agctggtctt tttcaccaat atttctcacg acttccgtac tccgttgaca
     3061 ttggttgccg acccggtaga acatttgttg gcggacaaga cactgagcgg agatcagcac
     3121 cggatgctca tgctgattca gcggaatgtg aacattcttc tgcgtctggt caatcagatt
     3181 ctggatttcc gtaaatatga aaacggcaag atggaatata ctccggttac ggtggatgtc
     3241 ctttcttctt tcgaaggatg gaatgagtct tttcaggcgg cagcccgtaa gaagcatatc
     3301 catttttctt ttgatagtat gccggatacg gattatcata cactggcaga catggagaag
     3361 ctggaacgta tttatttcaa tcttctgtcc aatgccttta agtttacacc ggaaaacggg
     3421 aaaatagccg tccgtctgtc ttcccttagt aaagaggaca agcgatggat acgtttcacg
     3481 gtggcaaata ccggttctat gatttctgcc gaacatattc gcaatgtatt cgaccgtttc
     3541 tataagatcg atatgcacca taccggttcg ggaatcggac tggcattggt aaaagccttc
     3601 gtagaaatgc acggtggtat gatctccgta gagagcgatg agaaacaggg cacggtcttt
     3661 accgttgaac tgcctgtaca gtcttgtgag gctgttgctg ccgaaccgga taccaccctt
     3721 gtttctgcgg attcccgtac aacagatgtt ctattggcgg aagaggaaga actggaaaaa
     3781 ggatatgact cttccaaacc gtccgtactg attattgatg ataatgagga tatccgttcg
     3841 tatgtccata cgttgttgca tacagactat acggtgattg aagcggcaga cggctccgaa
     3901 ggaatccgta aggctatgaa gtatgttccg gacctgatca tttctgatgt gatgatgccg
     3961 ggcattgatg gcattgaatg ttgccgccgg ctgaaaagtg agttacagac ctgtcatatt
     4021 ccggttattc tgctgacagc gtgttcactg gacgaacagc gtattcaggg atatgacggt
     4081 ggtgcggatt cttatatttc aaagccgttc agttcacagc tgttgctggc acgtgtccgc
     4141 aatctgatcg attctcaccg tcgtctgaaa cagttctttg gtgacgggca gacattggca
     4201 aaagaagatg tctgcgatat ggacaaggat tttgtagaaa gattcaagtc attgattgaa
     4261 gagaaaatgg gagactccgg tttgaatgtg gaggacttgg gcaaagacat gggactaagc
     4321 cgtgtgcagc tttatcgcaa gattaaatca ttgactaact actctccgaa tgaattgctc
     4381 cgtatcgccc gtttgaagaa ggcagcttct ttgcttgctt cttcggacat gaccgtagcg
     4441 gagattggtt atgaagtcgg tttcagttca ccttcttatt tcgccaagtg ctataaagag
     4501 cagtttggag agagcccgac agatttcctg aaaaggaaag gatgatttca ttgatatcgt
     4561 aaagagggat atatgaaaga ttataaagta gataaagaga gcttttccga atcctttcgg
     4621 aaggaagtgt acgaagtcgt atcccagata cctgtgggaa aagtatctac ttatggaggt
     4681 attgctttgc tgttgggggc accccaatgc tcgcggatgg tgggacgtgc attgaaagaa
     4741 gtgccggatg aattatccat tccctgccat agagttgtaa attccaccgg aaggctggtg
     4801 cccggttggg tggaacaaaa acaactcttg ctggcagaag aagtttcttt caaagctaac
     4861 ggatgcgtta atctgaaaga acatttgtgg cacgtggatg aatgaaggat gcaaggaagg
     4921 taagccatat catccgtatc catacaataa agaaaaccca tacatgaagc cataaggtcc
     4981 tggtaatgaa atctctgatg ggtataggga cgaatatgtc gataggaacg atacataaca
     5041 gcacaaaaca gcaccaaaat agaatcttgt ctgttgcggt acgtgttggt ctgctccaat
     5101 accagagcat gaaacctgcc aatgcgataa tataggtatg cttctcggcg gagtcactca
     5161 gtaatactac ccagcccatg agaatgccca aagcctgggc acggaaggca aaagacgacc
     5221 atttgcagaa attccccaaa aagagcagag tcagcaagcc gagcattcct atctgaagtg
     5281 cacggaagtg tggcaatgtc catgctgcaa tggggcgggc atagaaaaat gaatcataag
     5341 ctccggcgga ctgatgaaca gcaagactat ggcaccattc ttcataatag gggagcaaat
     5401 ctgcaggagc tattttgatt aacggtaatg caagcaatac aatgcccatt gtaacggcat
     5461 agccaaagtt acgccatacg tgaggatagc acagcaacaa tgccagttcg aaaattccat
     5521 atactttggt acatcccgaa atcatgatta acagaacagc cagaaatcca cggtcttttt
     5581 ccaataacgt ataggcgaat aagaataaat aggctaccgt tatgttatac tgaaatgaaa
     5641 gtaaactttg tcctaaaatc agtaacagaa aaaggaacat acggcatttc tgctgctggg
     5701 tgaattgttg gggcagcgtg aagatcgcca taaagaacag cgaataattg aatagattcc
     5761 acgcgaaagg tcccagccat gcaggcagat acgcaaacgg agcgaacaat accgtgaaaa
     5821 ctggagaata aaggaagtag cgtccgtgag cttctacaaa ttcagttgtg tatgggctga
     5881 tgccttgcca gaagaattga gtagcgtccg agaagaccat aaagttttga tgccgtcctc
     5941 gtataaattc gagcagagtc actataaaag cgagcaggaa acctatcatg tagagattcc
     6001 gccggctata gaaaaacggc attttggggt tctttttact aaggaactgt acttggcttt
     6061 tgtcgtctag tgtggcagta cctgtttgtt tttcttttgt tgtgtaatga caattatcct
     6121 tccccaggaa aattgtaata gccctgttga acatataaat ctagtttagt tattgacgcc
     6181 aaatatacgg tgtttaagtg aaatattcaa acttatttta tatttatctg ccggtttgtt
     6241 ctattttgct gagtgatagg ggaatattac ccggaaactt tccatatcat tacaaataaa
     6301 gccctctgta tgccccggat tttgaatata atttgtatgt ttaatccgtt ttttgtatct
     6361 ttgtgccagc aagatactgg aacaggctgt ttttatacat aaaaatgcta ttttttgcta
     6421 ttcgttgaaa ggattatctt atcaaattct attccttttt taattactca gtctgtcaat
     6481 aatcatttta ttaattattt cgggattcat tgttatttgt cccttattta aatcagaact
     6541 ttatacgata taaagaaaga ttcctgttat cgtttgttct tgtcttgctg tgtatattat
     6601 tttaataacc taaaccattt tattgtatga gtaaaataga aattaaagat ctctatctgg
     6661 tttttggcaa tgagaagcag aaggctttga agatgttgaa agaaggtaaa acaaaaagtg
     6721 aaatattgaa agcgaccgga tgtacagttg cggtgaaaga tgcgaatctt tccattaatg
     6781 aaggcgaaat attcgtcatt atggggctgt ccggtagtgg aaagtccact ttactccgct
     6841 gcatcaaccg tttgatacgc cctacttccg gagaagtgat tatcaatgga acagacatag
     6901 ccaaagtgtc ggataaggaa ctgttgcaga ttcgccggaa agaactggct atggtctttc
     6961 agaacttcgg tctgcttcct caccgttctg tcttgcataa tatagctttc gggctcgaac
     7021 tacagggagt aaaaaaggga gaacgggagc agaaagcgat ggaaagtatg caactggtgg
     7081 ggctgaaagg ctacgagaat cagatggtaa gtgaactgtc gggtgggatg cagcagcgtg
     7141 tcgggctggc gcgggctttg gccaataatc ccgaagtcct gttgatggat gaggccttct
     7201 cggcactcga tcctttgatc cgtgtgcaga tgcaggatga actgctgact ttgcagtcga
     7261 agatgaaaaa aacgattgtc tttattactc acgacctgag tgaagcgatt aaattgggtg
     7321 accggattgc tatcatgaag gatggagaaa ttgtacaaat cggtacatcg gaagaaatcc
     7381 tgaccgaacc tgccaacgct tatgtagaac gatttgtgga gaatgtagat cgaagcaaga
     7441 ttataacagc ttcctctgtt atggtagata aacccatagt ggcacgtttg aagaaagaag
     7501 gcccggaggt gctgatccgt aagatgcgcg aacggaatct gaccgttctt ccggtagtcg
     7561 attccaataa tctgttagta ggagaggtgc ggttgaatga cttgctgaaa ctacgaaaag
     7621 agcaaatccg ctccatcgag tccgtagtaa ggcatgaagt tcattcagtg ctgggtgata
     7681 cggtgctgga agatattctt ccgttgatga caaaaacgaa ctcgccaatc tgggtcgtaa
     7741 atgagaatcg ggagtttgaa ggcgtagtgc cactttcctc attgatcatc gaagtaacgg
     7801 gaaaagataa agaagaaatt aatgaaatca ttcaaaacgc aatagaatta tgataaatat
     7861 cggacaatat atagagactg ccattaattg gctcacagaa cattttgctt ccttttttga
     7921 tgctctcagc atggggatcg gaggattcat agacggtttt cagcacgtac tgtttggaat
     7981 acctttttat atcacaattg cagtgctggc tgcgctcgcc tggtttaagt cgggtaaggg
     8041 gacagccgta tttaccctct tgggtttatt gcttatttac ggcatgggct tttgggaaga
     8101 aacgatgcag acattggcat tggtactttc ttccacttgt ctggcattgc ttttaggcgt
     8161 tccgttggga atctggactg ccaacagtga tcgttgtaac aagataatgc gccctgtcct
     8221 cgactttatg cagacaatgc ctgcctttgt ctatctgatt cctgccgttc tattcttcgg
     8281 attgggaact gtgccgggag cttttgccac catcatcttt gcaatgcctc ctgtggttcg
     8341 tctgactggt ctgggcattc gtcaggttcc taaaaatgta gtagaagcct cccgttcttt
     8401 tggagctact ccctggcagc ttctttataa ggtgcaattg cctttggcat tgcctactat
     8461 tctgacggga atcaatcaga cgatcatgat gtcactttcg atggtagtga ttgccgccat
     8521 gatttctgcg ggagggttgg gagaaatcgt gctgaaaggt atcacccaaa tgaaaatcgg
     8581 actcggattt gaaggcggta tcgcagtcgt gatattggcg atcgtgctgg accgcatcac
     8641 tcagggtatg gcagataaca gaaaaagtaa aaagaaataa gaatcacacc aaagaaagga
     8701 ataatcaatg aataagataa aaatgattgc ggcaatgttt attgccggca tactcttaac
     8761 cttcgtttcc tgcggagaca acggaaagag taagaagata agtatcgctt atgccaactg
     8821 gtcggaaggt attgcaatga caaaccttgc caaagcgatt tttgaagatc aggggtacga
     8881 tgtaaagttg ctgaatgccg accttgcacc tatatttacc tctatctccc gtaagaaagc
     8941 agacgtattt atggatgtct ggatgcctgt cactatggaa gattatatga aacaatacgg
     9001 ggataaactc gaagttatcg gggatattta tgatggtgcc cgtatcgggc tggtgattcc
     9061 ggattacgtt acgatcaact caatcgaaga actgaacgcg gaaaaggaac gtttctccgg
     9121 tcagattgtc ggtattgatg ccggagccgg tattatgaaa gctaccgatc aggccatcaa
     9181 agactatgga ttggattata aactgatgac ttcgagcgga cctgccatga ctgcttccct
     9241 aaagaaagcg attgataaga aagactggat tgtcgtgacg ggatggacgc ctcactggat
     9301 gttcgaccgt ttcaagctga aagttcttca ggacccgaag ctgatatatg gaaatacgga
     9361 atccattcat accatagcat ggaaaggttt tagcgagaaa gacccttttg ctgccgaact
     9421 tttgggcaac attcgtctga cagatgcgga aatcagctct ttaatgactg ctctggaaga
     9481 ggcgcagaca acggaaagac aggctgcccg tcaatggatg gaagaacatc aggaactggt
     9541 aaacagttgg attcctgaga aagattgata tgcaaacact acttcaacca tcctgccatt
     9601 ctttctttac catagaagta gtagaaaagt agtcccagcc agctggtaag aacgattaat
     9661 acaatcgcta taagtctttt ctctacagcc gcatttatat tccaaatctc tatggcagct
     9721 ctgaaagtca gtatcaaacc gataatccaa ataacaaatc cgatcatatc tttagagttt
     9781 taatgaatat cttcgtgaga agtaatcgtt acttctaaga tataaacaaa aaaggcagga
     9841 atctgtttcc aggattcctg ccttttatta tgtataaagt atttctactt attattcagc
     9901 tgtatcagct ccccagtttt ctctggcaag acgtttgtag ctgttgtaac gccatttagc
     9961 gttttcttca gcagctttaa acagttcttc agcttcagca ggatattgtt tcattacaga
    10021 agcgtaacga acttcaccct tcaagaaacc ttggaagtct tcccagttag gttctttgct
    10081 atccagttgg aacggattct tgccttcttc ttccaaagca gggttgtaac gccacaagtg
    10141 ccagtaaccg cacttaacag ccttttcttc ttcttcctgg ctcttaccca taccggcttt
    10201 cagaccgtgg ttgatacatg gagcgtaagc gatgatcagt gatggtcccg gatatgcttc
    10261 agcttcacgg atagctttca gagtctgagc ctggtcagca cccatagcaa tctgagcaac
    10321 atatacataa ccgtaagtag tagccatcag accgaggtct ttcttacgta cacgcttacc
    10381 tgcagcagca aacttagcga tagcgcctac cggagtagct ttagaagact gaccacctgt
    10441 gttagagtaa acctcagtat ccaatacaag gatgttaacg tccttaccgg aagcgattac
    10501 atggtcaaga ccaccgtaac cgatatcata agaagcaccg tcaccaccga tgatccattg
    10561 gctgcgttta acaagatatt gttgcagatc agcgatttgc ttgcagtggt tgcatttatc
    10621 tttagcagct tctaccatcg gaatgatctt ttcggccagt tccttagtct tttctgcatc
    10681 cagcatattg ttgatccatt cagcaaatac ttctttgtat tcagccgggc agcaatcaga
    10741 agcgatagct tcgttcatta ctttcaccag acgggcacgc atcttttcgt tagccagttc
    10801 catacccaga ccaaattcac agaagtcttc gaacaaggag ttagcccatg caggaccgtg
    10861 acccttttcg ttcatagtgt acggagtaga aggaactgaa ccggagtaga tagaagaaca
    10921 tcctgtagcg ttagcaacca tttcacggtc accgaacaac tgagaaatca gtttcacgta
    10981 cggagtttca ccacaaccgg agcaagcgcc tgagaactca aacaacggag ttgcgaactg
    11041 agagttcttc acgttagcct tgatgtctac caggtgttgt ttgctcttca cgttttcagc
    11101 gcagtaagtc cagttatcag cttcggccaa ctggctttca aggtgtttca tggtcaatgc
    11161 cttgccaccc ttcttcggat tacccggaca gatgtcggca cagttaccgc aacccagaca
    11221 gtcgagaacg tctacctgaa tacggaatgt cataccatcg aatgctttac ctacagcttt
    11281 cagttgctcg aacttagcac ccttctgctc ttcagcatcg agtacgaacg gacggataga
    11341 agcgtgagga caaacgtaag cacacttgtt acactgaata cagttttcag cattccattc
    11401 gggaacgaat gcagctacac cacgtttttc gtatttggaa gtaccttgat accaagtacc
    11461 gtcttcgata cccttgaatg cagataccgg cagcaagtca ccgtcctgtg cattgatcgg
    11521 acgaactact tcgttgatga aagcaggatc attgttttct gcttttgcat catccggcag
    11581 gttagcccaa gcaggatcga cagtcagagt cttgtattca ccaccgcggt ctacagcagc
    11641 gtagttcttg ttaacaacgt cttcaccctt cttgccgtaa gacttaacga tgaatttctt
    11701 catctgttca acagcttgat ctacagggat tacgcctgtg atacggaaga atgcagactg
    11761 aaggattgta ttggtacggt tgcccaaacc aatttccatt gcaatctgag ttgcgttgat
    11821 atagtataca gagatgttgt tctgtgcaaa gtatttcttc accttgttag gcaggttctt
    11881 agccagttct tcgccttccc agatggtatt cagcaagaaa gaaccgttct tacgcaaacc
    11941 acgtgttacg tcgtacatgt gcaggtaagc ctgaacgtga caagcaacga agttcggagt
    12001 atttaccaag taagtagaac ggatcggagt atcaccgaaa cgcaagtgag aacaagtgaa
    12061 accacccgac ttcttggagt cgtaagagaa gtaagcctga cagtgtttgt cggtgttgtc
    12121 accgataatc ttaacagagt tcttgttggc acctactgtg ccgtcagcac ccagaccgta
    12181 gaatttagct tcgaacatac cttcaccgcc cagagcgatt tcttctttct gaggaagaga
    12241 agtgaacgta acgtcgtcta cgataccgat agtgaagtgg ttcttcggca ttggcatagc
    12301 caagttttcg aatacagaga tgatctgtgc cggagtggta tcttttgaac ccagaccgta
    12361 gcgaccgcca acgataacag gagcattttc tgcgccatag aagcagtctt taacgtcaag
    12421 gtaaagaggt tcgccgttag cacccggttc ttttgtacgg tcaagcactg cgatgctctt
    12481 tgcagtcttg ggtacagcag ccaggaagtg tttagcagag aacggacgat acaagtgtac
    12541 ggcaaccata cctacttttt cgccgtttgc taccaagtgg tcgatagctt cgcgggcagc
    12601 ttcagttaca gaacccattg cgataattac gcgttctgca tcttctgcac cgtagtaatc
    12661 gaacaaaccg tatttgcggc ctgtgatctt ggaaatttcg ttcatgtatt cttctacgat
    12721 agcaggaact gcttcatagt agttattgca tgattcacga tgttggaaga agtggtcggg
    12781 gttttcagcc ataccacggg caaccggctt catcggattc agtgcacggg cacggaattc
    12841 agccaaagct tcctggtcga tcagcggagc gaggtcgtcg ttttccaaca tttcgatctt
    12901 ctggatttcg tgagaagtac ggaaaccatc gaagaagttc atgaacggaa cgcgtgattt
    12961 gatagtagcc agatgagcaa cacctgccaa atccataact tcctgtacag aaccttctgc
    13021 caacatagcg aagccggttt gacgagctga cattacgtcc tgatggtcac cgaagataca
    13081 caatgcgtga gaagccagtg tacgagcaga aacgtggaat acacaaggca agaattcacc
    13141 ggcaatcttg tacatgttag ggatcatcaa aagaagaccc tgagaagcag tgtaagtagt
    13201 agtcaatgca ccagcctgaa gagaaccgtg aactgcaccg gcagcaccac cttcagattg
    13261 catttcctgt accaatactg tttcgccgaa gatgttctta cgtcctgcgg cagcccattc
    13321 gtctacgtac tcagccatag tcgaagaagg agtgatgggg tagatagctg ctacttcaga
    13381 gaacatatac gagatatgtg ctgcagcttg gttaccatca catgtgatga atttcttctg
    13441 tttagtcata actaaattaa atatttaagt aaataaatct ttttagtata agaatccgaa
    13501 catccaaaga ggtatttggt tgccgcggcc tatctcggcc ttttgcaacg catacgtcac
    13561 gtccgggtta ttctttattt ttgtaccttc cgcacaaatt ttgaacggca tcacttcgtc
    13621 taccatgaaa gagacgtttt tatctccttt atgtacctta tggtctttcc ataaagtgtt
    13681 aacgaagaac gtgtcgagta catcctgttc ttccactttc accggataaa tggagtacat
    13741 caggttagag ttgtgcatca taatctttga cggtttcttt gggaattctt ctcctttcgg
    13801 gtaaaccaga ttaatcagac gcgcgtctgc cagatacttg atatagttca ttaccgtagc
    13861 gcgggatgtc tgtacgtcac ttgccagttg gctcacgttc ggagctttcg gtccgtccac
    13921 agccaacaaa tatagtaatt tttttatctt tgaaagatat ttcagctcaa tttgtttgat
    13981 cagcaagata tccacttcta ccatcatgtt cattgttttc agcagattct ccgagaaatt
    14041 acgtttttca aggaagaaag ggtagaaacc atgatgcagg taatcctgaa aataatccag
    14101 cggtcgtact ttggaaagta ctcctttggc tatctgttca tgtgtactga ggatttcttc
    14161 gaggctgtat gcccggaatt tcattcctgt ctgcaggttc agaaattcac ggaaagagaa
    14221 tccgcgcagg ttataacttt tcgcaatgtc acgcaattcg aggttttcct ctttgagtcg
    14281 catgacggaa gaaccggtga agacaatctt caggctgggg aaacggtcat agcacattcg
    14341 tagctctttg ctccattcgg gatgtttgaa cacctggtcg atcagcagta cttttccgcc
    14401 acgtttctga aactcgttgg cgaagtcaac aaggctgtga ccggagaaat aaaagttgtt
    14461 catattgatg aacagacagg aacggtcggt gccgaatttc tctttggcgt actgcaggag
    14521 gaaagtggtt tttcctacgc cacgtgtccc tttgatacca atcagacggt cactccagtc
    14581 gatctcgtcc ataagatcgc ggcgaacggg ggcattggtg tgctcaacga ggtaggcgtg
    14641 tgtgcgatag aatgattcca tttcgtttct ttgtttttcg gctggcaaat atagtgcttt
    14701 ttttaggatt tgcaaagtag agatagcaaa aatgtgcttt aatttataag tttctcttta
    14761 ttgtgtaagt tcctgattat ttcctgtata tatttgcaga ataatgtgtt gaatccatct
    14821 ttgacatgac gaaaagacct gtttatatat tcaatccgga gcatgatatg gcgttggcaa
    14881 gcggtgagac gaactatatg gcgccggctt ccgcccgaca gatggcgagt gacctggcgt
    14941 tgcttcctat gtggtatgcc gaagcgggaa gtgcggtgct tgcaccgtct gcttataatg
    15001 cggacttcct gaaaacaaag agtgaacttt tgggcatgga tgtggccttg ttgacggaac
    15061 cggaagtggc tgacggtaaa gactggaagt tctctccgtg gggttgggac cctgctttgc
    15121 ggaagcgttt gatgacattg ggggcaggtc agacggagct gccttctgcg gattatatga
    15181 atattctgag agagcattcg catcgtctgc aggcggtaaa gttgttgcct gggttgcggt
    15241 tgaatgaata cttctgtgga gaatcttttt atttgagtac tttggcggag tgcagtgcgt
    15301 tcgtcgaagg gcgggaagcg tgcttgttaa aagctccgct ttccggaagc gggaaaggat
    15361 tgaattggtg taaaggcata tttactactt ttatttccgg ttggtgtgcc cgtgtcgctg
    15421 cttctcaggg tggggtggta ggcgaaccta tatataataa ggtggaagat ttcgctatgg
    15481 agttttatgc tgacgggaga ggaagggttg tttttgccgg atattcggtc ttccacacgg
    15541 gtgggagtgg gatgtatgca gggaatgact tgctgtctga cgagaagatt ctgcagaaac
    15601 tatcggctta tgtgccacaa gaagaattta tcaggctgcg gactcgtttg gaagaagaat
    15661 tgtcagcttt gttcggtggc ttttatcatg gatacttggg agtggatatg atgatttgtc
    15721 attttccgga tgaagcgcct gtttaccgga ttcatccttg tgtcgaaatt aatctgcgaa
    15781 tgaatatggg ggtggtggca tggctcttga cggatcgtta tttggctgcg gatgcggaag
    15841 gagtttttcg gattgattat tatcctttag ccggtcaggc tttggaggaa catcggcaga
    15901 tgtcggcttc gttccctttg tccgtagaga ataatcgggt gtgtgccgga tatttgccgt
    15961 tagtaccggt gacgcctcaa agccggtatc gtgcgtttct tttgcttact ctcccccagt
    16021 gaaaaagata gtgcttttgc tctcatgctc taacagttcg tctgtatccc tttattcatc
    16081 gatgttttag ctgttagaga tccagtggta gcagagtgag agcaaggact tgctctcact
    16141 ctgcatcgtc ctgataaata ctgtttttac tgtgttattc tttgatttac aggatgttaa
    16201 tatctgatat ctcaactgtt aacgtttgat ttctcagata ttaataattg agaaatcaag
    16261 tattaaggac tgataattta tgtattattg actgatatat gatttaatgt tttcagagag
    16321 agcagtacta ttgaagtagc tgatgcgttc aatgtgattg gaacatgcgg ttaagtcaat
    16381 caaatcaaca gtagtttcag atagtttcga gcgtttggaa ctaaagtttc aagcgtatga
    16441 aactctagtt tctcaccgat gaaactacag tttcacaccg atgaaactct ggtttcaagc
    16501 aatggaaact ctttgaagat actgctaaat tggaattggt gatgtgtact ggttttagtt
    16561 gacaacttcg tttgttataa ctgaattagt ttactcaata tactttaata tctaaatagg
    16621 tttacttttg ttattctt
//
