LOCUS       c00075_gnlPro..        16197 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMIMLNGG_75.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:56:16
            Original ID  :: gnl|Prokka|OMIMLNGG_75
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16197
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16197
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3217:6197]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3218..6197
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16197
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16197
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(497..2062)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-48, bitscore:
                     155.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVA
                     SCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGKGKNIPD
                     ESICARIRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAINQKEVE
                     AMKVQGVPSVFADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVG
                     GGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGQQLANDLLTHIN
                     DYPVDILEHRRVDKVELDGSAKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGK
                     GVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEK
                     AKSLPNVEVFLHSQSLEVLGNGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVF
                     RDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMR
                     GLIG"
     CDS             complement(2067..2633)
                     /locus_tag="ctg75_2"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(2988..3098)
                     /locus_tag="ctg75_3"
                     /transl_table=11
                     /translation="MSHIHETIDLTPFVFEQIFDLISGIVYRFFLCKGYL"
     CDS             complement(3218..3868)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 55.4;
                     E-value: 2.7e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-34, bitscore:
                     110.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGCPLRCLYCHNPDTWEVKRETPYLLEPEALLAEVLRYKNFIAK
                     GGVTVTGGEPLLQPEFLKEFFRLCRENGIHTALDTSGYICSGKALEVLEQVDLVLLDIK
                     TIDAGLHPRLTAVKLDNTLRFLDELEKRGIPVWIRHVIVPGLTDDDEALSKLAEYISSY
                     NVVQKAELLPYHTMGAYKYEAQGLDYKLKGVEPLSAERLANAKAIFMKHGITV"
     CDS             complement(3957..6197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_5"
                     /sec_met_domain="Gly_radical (E-value: 2.1e-45, bitscore:
                     144.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.3e-281, bitscore:
                     926.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFERMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQVNNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINNSL"
     CDS             complement(6625..9354)
                     /locus_tag="ctg75_6"
                     /transl_table=11
                     /translation="MNKRFSTLLAAALVAGSFSSAFAQLEGRNVEWKDAQASRAYYLAG
                     VHFVSPTDYLQAFSLQGLVNGADITAANPVAAAQWTVETKKVGTVTHYAFKNIEGEQYL
                     AFEKKDGAYALAAKKEANDETKSFRWFTVAANGNLQAVLSDEKEPYFLGLKNDGTADWS
                     LALLQSSEHHTDGSTSVIKKKVALYEIYNDQITAEAFASKFGENFTIEFPETLDDMDVF
                     ENVSVEKIANDNLGFKLVDNKGTKDTKDDEYVVLANERVSNSELAANAIGYRYAKMTAK
                     AIKDKKIDDKNTVFYAEENETNIGDGKYALVQKVKVGDLDNKDVTFGKVTNDETTRQLA
                     SVEYDCHSTFMGVTVGKGTRVANTEVANERMLIVNVTAKVADKKNSSALGLKNDFTGAR
                     WYDKVSEADFDQPQGQWLVAAGSAANTIKLINVQKPGFVQDNIRLYEAEGENTYTVFAS
                     DLGLSGLETITLTKVEDYDKLNGYYSTLSDINQKFAFVTTGEYANEEAGSDLYLKAGVE
                     GDVVTVVPHAGSEWELIRNEKAQAVTANYKYYDGEKWVELNGKGNEEKGILPADTVRLA
                     YSYAINADELGLGTAWKMAKDDIEFFLKENGKGTYAIVYGATADEVKEYGVINGSEELV
                     AETTDFTNSTPFEIIDLDAAPSLAADSKHMTFEATNSIGFIASDENNNAVLAKETAALW
                     VDSVNAEGYATPKFFISYAGKMMTTAKKFKEIVDKAYANDEISKKEYAELTADENLYYK
                     SVERIKFVDAERLSGEDTLVIADEKYTGKDIEDFKFKVTENEDGDYVLKANGNYVYVIN
                     GNLVYGTDAKEAEAFVIEVTSAPTANEGIATSEVKVIAGEGNVTIAGAAGKKVVISNIL
                     GQVVANTVVSSDNATIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             complement(10022..10474)
                     /locus_tag="ctg75_7"
                     /transl_table=11
                     /translation="VNLPVVCLEVGIELSGIVDTALFQYVQHAFLFVRRERAFAFSHAV
                     VSPASEPSHQLANGFLHQFVGHPVQHPDETERIGQFIGRAEISTSVGLLLLVFRADDVP
                     QFDFVADLLFCDSPQASSGFGAILFHAEQIGGGDVGGVDFFFHIFH"
     CDS             complement(11090..11353)
                     /locus_tag="ctg75_8"
                     /transl_table=11
                     /translation="LGIEFVIEGQDKTGYGDRIAMVFLASVVRTPETVDAVVHKVCEDL
                     PISAEAELVISGCINVCGLFHCGFFCRCFFLFLCKCRYTRGE"
     CDS             complement(11360..11635)
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="VPGRRKDGRFAFRTRSSEEVDRLVMLVGQTDRDDQMTGTDIEGRM
                     DKTCDVELFQSNFTAFFNFHFVFSVFCVFYLIGTSRTSSLKFYFCS"
     CDS             complement(11822..12220)
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="VLAFAFFLWVVVFVADERIDYGYAHIVFTNRTQVEPHFTTVADRT
                     FGDRGCLCIRRTAALVVVDTAEVVGFAQVAVYHVCACGDIFVFVLQVSRIDAQRYVSIF
                     DVCFRFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             12434..13699
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATMLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPALDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAVVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
     CDS             13921..15279
                     /locus_tag="ctg75_12"
                     /transl_table=11
                     /translation="MDMDKIDVPNGYALSAGTSTIFLNSSVAYDTNADWITGANSIRFN
                     NGDGLYDDVRTSNNGDGGGLGPVYAGYSCGSCHRNAGRTKPTLWENGGSGNYGFSSMLV
                     YISRRNGAFFRDYGRVLHDQAIYGVKPEGKLSVTYDKQTFSFPDGETYELCKPNYTITE
                     WYKDSIAPEDLFCTVRIPLRHVGMGQMMAIDRREIEALAAKSNYPEYGISGRCNYITEK
                     GVTGVGLSGNKAQHLDLTVELGFSSDMGVTNSRYPEEICEGQAQINQGSMMGLSYDQLD
                     ISTADMEDVDLYMQSLGVPARRNINDPQVILGEQKFYEAKCHLCHVTTLHTQAGGSTLL
                     NGTRLPWLGGQTIHPYSDFLLHDMGSEIMGVGLNDNYVSGLARGNEWRTTPLWGIGLQE
                     KVNGHTYFLHDGRARNLTEAIMWHGGEGEASKNLFKQMSKEEREAVIAFLNSL"
ORIGIN
        1 cccggatgtt aaggatggca acatgggggt gtttacgaaa ttatgtgctt gtctttgcta
       61 aaaaaagaga gggcttttgt ggaatgaaga accgtatttc gtcaatttaa cacctattgc
      121 attcgttttt acatttgttt attcgattat tttatatgct ttttcaaagg caaaagaaag
      181 caatatattg gtttccaatc atatgataaa aacgtcctgt tagaggagtg atagaggcag
      241 tgatacagga tgttttcctc tatcactcct ctaacgcttg aatattaata gctacaacct
      301 tcgtagtgat agagtgatag aggatttgta gaaaacttcg tatggagatc acaaccttgg
      361 aaaattttga tgcggttgcc ctgttggtga aagtcggggt tttgtgcgta aaaaaaagaa
      421 aaggtgtgca attttgaaca cacattcatg cagttcaata ttgcacacct tcgtcattca
      481 taacaaatac taaatattaa ccgattaaac ctctcatacg gtcttcaaaa gcagacagag
      541 ctgctttcgc tccttctccc attgctatga ttatctgttt gtagggtacg gtcgatacgt
      601 cgccagccgc atagatgccg ggaacattcg tccgacaatg cgcatcgatt acaatctcac
      661 ccggtttgtt cgtttcgaca acgtcgcgga aaacgccact attggcagcc aagccgattt
      721 ggacaaagat tccgtccagg tcgatcaccc gctccgcatc cgtcttacga tcttttacac
      781 gaagacctgt caccttatcg ccattaccga gcacttccaa agattgggaa tgcaagaaaa
      841 cttccacatt cggcaagctc tttgcttttt cctgcaacac ttggtcggct tttagctcgt
      901 ccataaattc cagaaccgtc actttcgaac aaatgccagc caaatctata gccgcttcga
      961 tacccgaatt tccaccgccg acaaccgcta cgtgcttacc tttatagaac ggaccatcgc
     1021 agtgagggca aaaagcgaca ccttttccga tatagtccgc ttcgcccgga acattcaact
     1081 tgcgccagct tgcacctgtc gccacgataa gggcaggagc agaaaaacgt tcaccggtag
     1141 aagtggtcag aagtttcgcc gatccatcca gttcgacttt atccacacgg cgatgctcca
     1201 gtatatcgac cggatagtcg ttgatatgtg tcagaaggtc gttcgccaac tgctgtccgg
     1261 tagtctgagg aacggaaatc aggttctcga taccgaccgt ttctttgacc tgtcctccga
     1321 tacgttcggc tatcactgcg acattcaagc ctttacgtgc cgagtagatg gcagaagctg
     1381 caccggcagg tccacccccc actattaaca catcatagtt cttaacaggt ttttcaacag
     1441 agttatcaac acccccttca ttaattccgt attgggcttc gagtttggaa agcaattctc
     1501 ccaaatcact acgccccaca ttgatcagtt tgccatcggc aaaaacagaa gggactccct
     1561 gtactttcat ggcctcaact tctttttggt tgatagcgcc atccaccgtt tcgtgggtga
     1621 tccggctatt gagagtagcc atgacattga gtgcctgcac tacatccgga caattggtgc
     1681 aagtaagaga aacataagtc gtcagcttga tcggaccatt caaggctctg atacgggcac
     1741 agatactttc gtccggtata tttttacctt ttccatcact attcaggaca gctaacaaca
     1801 aggatgtaaa ctcatgtccg ttaggtactg cacgaaaccg gataccggta ggcataccgt
     1861 cttttacaat tgtaaactga agtccttcgc catccgcaac gctgcatgac aaatgatccg
     1921 agcatgatgc cacatcacca agcaggtcta ttagctcctg acggctttcg tgatcgggag
     1981 cgacttgtat atcaaataca tattgggata ccagtccgga gaaaataccc gaaagctggt
     2041 ctttcattgc tgagtctaac ataactttag atcttaccaa ccaagtcgat actcggcttc
     2101 aaggttgctt cgcctttttt ccactttgca ggacaaactt cgttcgggtg agaagcaacg
     2161 aactgggcag cttcaacttt acgaagcaat tcgtctgcat tacggccgat accgttatcg
     2221 tggatttcgg caatcttgat ctttccctcg ggatttacca ggaacgtacc gcgataagcc
     2281 ataccctctt cttcaatcat cacaccgaat gcacggctta aagcccctgt cgggtctgcc
     2341 agcatcggat atttgatctt acggatcgtt tcggaagcat catgccatgc tttgtgtaca
     2401 aagtgcgagt ctgtacttac ggaatatact tcgacaccca tctcctgaaa tttgccgtac
     2461 ttgtcagcca tatcgaccaa ttcggtcgga catacgaacg taaagtcggc aggatagaag
     2521 aaaaagatgg cccatttgcc cttgatatct tcgctactta ctgtcttgaa actaccattc
     2581 tgaaaagctt gaactttgaa ttcgggtact tgtgaattga taattggttc catgattttt
     2641 actatttaat ttgttactac tattttttgt ttaccctaca aaggtaaatc gtaagatact
     2701 gattgaaaga atttttcaaa ttgataattt ttatctgccg atagacggat ttctatctgc
     2761 aagcatactt atctactatg acaataggaa gcaaagtaat gttttccgga acaataaaaa
     2821 tatacctaat tgtaggtaaa atacctttcg atcataccat gtgattcttt aattgttaac
     2881 tttggatgtt aacttaaaaa tattcgaaga tgagaagagc tagtttgtat aatacatttt
     2941 cagcaagtct attgctcgtt tgcaacgcat gtctttcttc atgtgtctca caaatacccc
     3001 ttacaaagga aaaaccggta aacaattcca cttatcaagt cgaatatctg ttcgaacacg
     3061 aagggtgtaa ggtctatcgt ttcatggata tgggacatta catctatttc accaactgcg
     3121 agggagatgt taccagtatt gaaagcgaca gtgtccgcac agtcaaccgg atcagccgta
     3181 aaccgatcat catcaaagag cagacactcg attaggctta tacggttatc ccgtgtttca
     3241 taaagatcgc tttcgcattg gccagacgct ctgctgaaag cggttccaca cctttcagct
     3301 tatagtccag gccttgtgcc tcatatttgt aagctcccat tgtatgataa ggcagaagtt
     3361 cggctttctg gaccacgtta tatgaactga tatattcggc cagcttgctc aaggcttcat
     3421 catcgtccgt caggccgggc acgatcacgt ggcgaatcca tacagggatg ccgcgtttct
     3481 ccagttcatc aagaaagcgt aaagtattat cgagttttac ggccgtcaaa cggggatgaa
     3541 gaccggcgtc gatcgtcttg atatctaaca gaaccagatc gacctgttcg agcacctcca
     3601 atgctttacc ggaacagata tagccggaag tgtccaacgc cgtatgaata ccgttctcac
     3661 ggcaaaggcg gaaaaactct ttaaggaatt caggttgtaa caaaggctcg ccaccggtca
     3721 cggtaacacc acctttagcg ataaaattct tatagcgcag cacttcggca agcaacgctt
     3781 caggttccag cagataaggc gtttcacgct ttacctccca agtatccgga ttgtggcaat
     3841 acagacaacg aagcggacat ccctgcataa aaacgacaaa gcgaattccg ggaccgtcaa
     3901 cggtcccgaa actctctaaa gaatgtatac gccccaacat attaatcaat ggacaattat
     3961 aaactgttgt tgatggtgcg cgagataacg tcgagttgct gttcgcgtgt cagcttaacg
     4021 aagttgacgg catagcccga aacacggatc gtaagctgcg ggtatttctc cggatgttcc
     4081 atcgcatcta acagcaagtc tttatcgaat acgttcacat tcagatgctg gccgccatcg
     4141 ggcgtgaaat aaccatctaa gaggctcact aagttgttca cctggatatc gcgttcctta
     4201 cccaacgttg caggagaaac ggcgaatgta taggaaatac cgtcatgcgc atgctgaaaa
     4261 ggcagtttgg ctacagaagc caaagcggcg acagcccctt tcgtatcgcg tccgttcatc
     4321 gggttggctc ccggagcaaa cggcgtaccg cccggacggc cgtcgggagt cgttccggtt
     4381 ttctttccgt agaccacgtt tgatgtgatc gtcaggatag attgtgtcgg agttgccttg
     4441 cggtatgtct gatgctggcg cagatattcc ataaacttct cggtaatgtc gacagcaata
     4501 ctgtccgtgc ggtcgtcatt gtttccgaaa ggtacatatt cgccttcgcg ttcgaagtcg
     4561 acagccaaac cacgttcgtc acggatcact ttcactttcg tatcacggat ggcagccagc
     4621 gagtcggcga cgatagaaag gccggcgata ccggttgcgc gaatacgttc cacatctccg
     4681 tcatgaagcc ccatctcgaa tgcttcatac gcatatttgt cgtgcatgta gtgaatgatc
     4741 ttcagtgcat tgacatagac ttttgccaac cagcgcatca tctgctcgta tttctccatc
     4801 acttcgttgt aatccagata ctcgctggtg atcggttcga aacggggagc cacctgcaca
     4861 cccgatttct cgtcacgtcc gccattgatc gcatacaaca agcattttgc caggttggca
     4921 cgagctccga aatactgcat ctgcttgccg attttcatcg gagacacaca gcaggcgata
     4981 ccgtaatcgt cgccatagtc cggacgcatc agatcgtcgt tctcgtactg gatggcagag
     5041 gtatcgatcg atacttttgc gcagaagttt ttccagttat ccggagcatt gttgaaccaa
     5101 agcaccgtca ggttgggttc gggtgccggg ccgaggttat acaaggtatg cagataacgg
     5161 taagatgtct ttgtcaccag cgaacggccg tcaacacctt gtccgcccag cgattcagtc
     5221 acccaaacag ggtcgccgga gaacaggtcg ttgtattccg gagtacgcag gaaacggaca
     5281 atacgcagtt tgataataaa ctggtcgatc aattcctgtg cctcttcttc cgtcagctta
     5341 ccttcgcaaa tatctttttc gatatagata tcgaggaaag tagaagtacg tccgagagac
     5401 atggctgctc catcctgatc ctttacggct gccaggtaag ccagatacaa gaactgcacg
     5461 gcttcgcggg catcctttgc cggacgtgtc acatcgaaac cataaccggc acacattctc
     5521 tcaaatgctt tcagcgcttt gatctgctcc gttatctcct cgcggctctg aatgatttct
     5581 tctgtcagtt cctgtatatc gagacgtttc tggaaacgtt tcttttcttc gatcaggatc
     5641 tgggttccgt acagaggtac acgacggtaa tcaccgatga tacgtccgcg tccgtaggca
     5701 tcaggcaacc cggtaatgat ggcggaacga cgtgccgcaa tcatctcgtc tgtataggct
     5761 gaaaaaacgc cttcgttgtg cgtctttctg tatttggtga agatttcttt tgtcatcgga
     5821 tccagatgat agccataggc ttccagactg ttttcgacca tgcggatacc gcctttcggg
     5881 aagataccgc gcttcaacgg ggcgtctgtc tgcaagccga cgattacttc gttttcctta
     5941 tcgatgtaac cgggtccgta tgtgtcaatc ccctggggaa gcttcgtttc ggcatcatat
     6001 actcctttct ccctttcaac cttaaacatc tcggttagtt tgttccacac tttcttcgtt
     6061 ttctccgaag agggtacgag gaacgtatcg tctccgttat aaggtttgta attgttctgg
     6121 ataaagtctc ttacattgat ctcctttttc caggtttctc ctttgaactg cgcccagttc
     6181 tcgttttcaa acttcataag cttatcttgt ctatttcggt ttaggcacgc aaagatacgt
     6241 cttttccccc tatctgaaaa ggattgtaaa ggacgaggaa tgttaaaccg gagaaaatac
     6301 ctacaaatag ggataagggg aataaaaacg aagccccggc agtacgaata ccgccggggc
     6361 ctgttttttg tctgccatcc ggtcttcaca gagggaaaag cagtagaact tttaatttca
     6421 ttactttagt attattaata ttaaatccaa ccgcttgttc gcctgtcgca gggtaattga
     6481 aaccatagat caagaaaacc tcttacatac ggtttcacgc aggttgtcta gaattatttg
     6541 attataaaat gtcattgtgc ctgtgtaagg gtggttcact aaccaccctt acgatagaca
     6601 gtattgtttt tttagtatca atcgttactt aacgatagct tttacagcag cttcgccttc
     6661 aacagctaca actactacgc ctgccggagc agcgatagtt gcgttgtcag aagaaacgac
     6721 agtgttagct actacctgac ctaagatgtt gctgataaca actttcttac cggcagcgcc
     6781 tgcgattgtt acgttacctt cgccagcgat cactttcact tcagatgttg cgatgccttc
     6841 gttggctgta ggagcagaag ttacttcgat tacaaatgct tcagcttcct tagcatctgt
     6901 accgtaaacc aagttaccgt tgattacata tacatagtta ccattagctt tcagtacata
     6961 gtcaccgtct tcgttttcag taactttgaa cttgaagtct tcgatatcct tgccagtata
     7021 cttttcatcg gcgataacca aagtgtcttc accagacaga cgttcagcgt ctacaaattt
     7081 gatacgttct acactcttgt agtaaagatt ttcatcagca gtaagttctg catattcttt
     7141 cttgctgatt tcatcattag cataagcctt atcaacaatt tctttaaact tcttagcagt
     7201 tgtcatcatc ttgccagcgt aagaaatgaa gaacttcgga gttgcataac cttcagcatt
     7261 tacagagtca acccacaaag cagctgtttc tttagccaat actgcgttgt tattttcgtc
     7321 agaagcgatg aagccaatgc tattagtagc ttcgaatgtc atgtgcttgc tgtcagcagc
     7381 caaagaagga gcagcatcca agtctatgat ttcgaacgga gtagagttag taaagtcagt
     7441 tgtttctgct actaattcct cagaaccatt gattacaccg tattctttta cttcatcagc
     7501 agtagcgcca tatacgatag cgtatgtacc tttaccattt tctttcaaga agaactcgat
     7561 gtcatcctta gccatcttcc aagctgttcc caaacctaat tcatcagcat tgattgcata
     7621 tgaataagcc agacgaactg tatcagccgg caggatacct ttttcttcat tacctttgcc
     7681 attcagttca acccattttt caccgtcata atatttgtag ttggcagtaa cagcctgtgc
     7741 tttttcgtta cggatcaatt cccattcaga accagcatga ggaacaacag ttacaacatc
     7801 tccttctaca ccagctttca aatacagatc tgaaccggct tcttcgttag catattcacc
     7861 tgttgttaca aaggcgaact tctgattgat gtcagacaat gtactgtagt agccgttcag
     7921 cttgtcataa tcttcaactt tcgtcaaagt gattgtttca agaccagaca aacctaaatc
     7981 agaagcaaat actgtgtaag tattttcacc ttctgcttca tatagacgga tattgtcttg
     8041 tacaaaaccc ggtttctgaa cattgatcaa cttaattgtg ttagcagctg aacccgcagc
     8101 aaccaaccac tgcccctgtg gctgatcgaa gtcagcttca gaaactttat cataccaacg
     8161 tgcgccagtg aaatcattct tcaaccccag tgcagaagaa ttcttcttgt ctgcaacttt
     8221 ggcagttaca tttacaatca acattctttc gttggcaact tcagtattag cgacacgtgt
     8281 acccttgcct actgtaaccc ccatgaaagt agaatggcag tcatattcga cagaagccaa
     8341 ctgacgagtt gtttcatcat ttgtcacttt accgaaagtc acatctttgt tgtccaggtc
     8401 accaactttt actttctgaa ctaatgcata tttaccatct ccgatgtttg tttcgttctc
     8461 ttcagcatag aatacagtgt tcttgtcgtc aattttcttg tctttaatcg ctttagcagt
     8521 catttttgca tagcgataac cgattgcgtt ggcagccaac tctgagttgg aaacacgttc
     8581 gtttgctaaa actacatatt catcgtcttt tgtatctttt gtgcctttgt tgtcaaccaa
     8641 cttgaaaccc aaattatcat tggcgatttt ttctacgctt acattttcaa acacatccat
     8701 gtcatccaat gtttccggga actcgattgt gaagttttcg ccaaacttgc tcgcaaaagc
     8761 ttctgctgta atttggtcgt tgtagatttc gtagagagct accttcttct tgataacgga
     8821 agtagatcca tccgtatgat gctcagaact ttgtaataaa gccaatgacc aatctgctgt
     8881 gccatcgttc ttcagtccta aaaaatacgg ttctttttca tcagaaagca cagcttgcaa
     8941 attgccgttt gctgcaacag taaaccaacg aaacgacttt gtttcatcgt ttgcctcttt
     9001 tttggcagct aaagcataag ctccatcttt cttttcaaaa gccagatact gttctccttc
     9061 aatatttttg aaagcataat gtgtaacagt tccaaccttt ttagtttcaa cagtccattg
     9121 tgcagcagca acaggatttg cagccgtaat atcagcacca ttcactaatc cttgcaaaga
     9181 aaaagcctgc aagtaatctg tcggactcac aaaatgcacc cctgccaaat aataagcgcg
     9241 gcttgcttgt gcatccttcc attcaacatt acgcccctcc aactgtgcga aagctgaact
     9301 aaaagaaccg gctaccaaag cggcagccaa aagagtagaa aatctcttgt tcataatcta
     9361 aaatgtttaa ttaataataa tatgtatatt gaatatcgtt cttacttcct gtttaacagg
     9421 tttttaccaa attcctgtat tttgacgaga gaaaacgtac gtttttttta gtcatttttg
     9481 aggggctttc gggagggttt gtgttggaaa gctggttttt cgtacttgtt aagctatctg
     9541 attgataaga aagaatatag aaaaggaaaa ataattggaa gaaaggattg caggttcaaa
     9601 aagtagttgt atttttgtgc agtgaaaatg gcgaaagaaa acgtacgttt tttcgctatt
     9661 tttcttctta tacccatata cttcttatta gcaatgactt acattgaaaa aagtgcctaa
     9721 agccatataa aaaaagagct gttttcaacc gctcgccaaa cttttttaca tcttcatcaa
     9781 aacaaagata atcaatcacc tataagatta actcccttta ttcacattgg aggggaaaaa
     9841 cggcaaaaac agcaggtttc gtaatttcat cttggaaaag ctcccccttc tgttaaagat
     9901 atacaaaata cggagtattg gttgcttagc tcaataacag cttcaagact tgcaaaacct
     9961 tacattatta tgtatcttta catcaacgtc cgtcacagac ggatcaaaca actataatac
    10021 attaatggaa tatatgaaag aaaaaatcga ctcctccgac atccccacct cctatctgct
    10081 ctgcatgaaa caagattgcc ccaaagccac tacttgcttg aggagaatcg cagaacaaca
    10141 gatcggcgac gaagtcaaac tgtggcacgt catcagccct aaataccaag agaagcaaac
    10201 cgaccgatgt gcttatttcc gccctgccga taaactgacc tatgcgctcg gtttcatcgg
    10261 gatgctggac cggatgccct acaaactgat gcaggaagcc atttgcaagc tgatgagacg
    10321 gttcggacgc aggacttact accgcgtgcg aaaaggcgaa cgcccgctct cgccggacga
    10381 acaaaaaagc atgttgaaca tactgaaaca gtgcggtatc aacgatcccg gaaagttcga
    10441 tgcctacttc gaggcatacg actggtaagt tcacatgacg ctacttgcct acgtattggt
    10501 tgtgccatac ctatgtaacg accgtttcct cggcatgaaa cggttgtgcc aagcttatgt
    10561 aacaggcgtt tcctactcag gaaacagttg tgccaagccg atgtaattgt tttggcacag
    10621 ccggagcagc aaacataccc ttgcgggaac aagtccaaga ctcgacgccg aacagattcc
    10681 ggacagaagc gaatgggaaa cggaaacata aaaaagaagc ctctcttcac agagaggctt
    10741 cttttttata ccgaaaataa ccaataaaaa cttttcgata tagttaatca tcttatatgc
    10801 ttacataatt gacaaaaggt tttgatatag cgattatact aatagtgtta ctttcttaat
    10861 gacattgcaa agatacgggt acttcccacc tcctacaata cctatatgtg agtaaaaaaa
    10921 cgtcttttac tacctaatca aggtgatatt caggcgcaat acctacaaat gggtaacatc
    10981 ggaacctttt tacctactaa ttgcgattgc acaccgttga cagcccctct aattttgcca
    11041 aaaattaaaa aacgcaatga aaaggttaac taatttatta gcaatcactc tactcacctc
    11101 ttgtgtaacg gcatttgcac aggaacaaga agaaacaacg acagaaaaat ccgcagtgga
    11161 acaatccgca gacatttatg cagccggata taacaagttc cgcttcggcg gatatgggga
    11221 gatcctcgca aactttatgg actacggcat caaccgtttc cggggtacgg acaacggaag
    11281 caagaaagac catcgcaatt cgatctccat accccgtttt gtcttggcct tcgattacaa
    11341 attcaattcc caatgggtat taggagcaga aatagaattt gaggctggag gtacgggaag
    11401 tgcctatgag atagaaaaca cagaaaacgg agaatacgaa atggaagttg aaaaaggcgg
    11461 tgaagttgct ttggaacaat tccacatcac acgtcttatc catccggcct tcaatgtccg
    11521 tgccggtcat ttgatcgtcc cggtcggttt gaccaacgag catcacgagc cgatcaactt
    11581 cttcggaact tctcgtccgg aaggcgaaac gaccatcctt ccttctacct ggcacgaaaa
    11641 cggtatcgaa gtgttcggta cgttcggccg aggctacaca cgtttcaact accaggcttt
    11701 ggtcgttgcc ggattgaacg ccaacgggtt cgaccgcaat acatgggttg ccggcggcaa
    11761 gcagggacta ttcgaaacag acaacttcac ctcaccgggc tatgtggccc gcctgaacta
    11821 tttaggagta ccgggattga aaataggcgg ttccttctac tattgccaca atacgggagc
    11881 caattccgac aaaccggaaa catacgtcaa atatggaaac atacctttgc gcatctatac
    11941 ggctgacctg caatacaaaa acaaatatgt caccgcacgc gcaaacatga tatacggcaa
    12001 cctgagcaaa gccgacgacc tcagcagtgt caacaaccac caaagcggcg gttctcctta
    12061 tacacagaca accccgatcg ccaaacgtgc ggtcagctac ggtggtgaag tggggttcaa
    12121 cctgcgtgcg gtttgtaaag acaatatgag cgtacccgta atctatccgt tcgtccgcta
    12181 cgaatactac aacccacagg aaaaaggcga aggcaagcac acgatggatt tacgcaacaa
    12241 agtaagcatg tggacagccg gagccaattg gtatgcttta cctaatcttg tcgtgaaagc
    12301 agactataca acacgcaaaa tcggaggcgg caaatataac agcgaaaacg aattcagctt
    12361 ggctatcgcc tatatcggct ggttcctcag caaataaaaa caatataaac aaattaataa
    12421 cttatcaata aaaatgaaaa agaaaaatta tttctatctg gcagccttat cgctcgccat
    12481 gacattctcg atgggagcat gtagcgacaa caacgacccc aatccggatg gtggcggaaa
    12541 agatccggtc aacctggatt acagttctga aaacgccagt gcatggggta actatatgta
    12601 taacgttgca atgttgctga acgacgatgc aaccatgctc tacaattctt gggtaaccga
    12661 ctacgtcgat gagcagggtt cacacggccc atatgccacg attttcaaag accagactgc
    12721 cggagcttac caaagcccgc tctcgtgtat cgaggaaatg atcgaaagcg gtatgtggaa
    12781 catcgccaac gaagtaggtg acgccaagat caaggacccg tataccaaat ataccagcgg
    12841 tgacaaggaa ggcggtctct atgccgtcga atcatggtat agctggcatt cgcgcgacga
    12901 ctatacgaac aatatcttct ccatccgtaa cacatactac ggccgcatcg acgacaacga
    12961 cgtgtccaaa gtagacggaa acctgagtgc attcaactct tacaaagatt tcgacgatga
    13021 aggagacatc gcagaacact cgctttcaaa actgatcgct tcaaccaacc cggctctcga
    13081 cgaagaaatc aaaacgctga ttttcgcttc tgcaaaggcg atccaggcta ttccgcaacc
    13141 gttccgcaac aacatcgaca gcgaagagtc cgttgccgca atgaacactt gcatggaact
    13201 ggccaacctg ttgttaaatg aagtaaaacc gtatgtaaac caaacattcg gcgatcctga
    13261 atacgacgat gaccttgatg caatagccga acagtttgtc gatgcggtcg ttcttcctac
    13321 ttataaagac ttgcaggaaa agaacaagct tttgctggat gcggtaaacc agttcagaca
    13381 aaacccaagc aacgacaact tcgaaaaggc ctgcaattta tggatcacgg cacgcgaacc
    13441 gtgggaaaag agcgaagctt tccttatcgg tccggtcgcc aacttaggtc tggaccccaa
    13501 catggacagc tggcctttgg accagaacgg tatcgtacag gtattgaatt cacaaaactg
    13561 ggatgacctg gaatggagcg gaaactttga cgaagaagat gaagccatcg gagccgcaca
    13621 gagcgtacgt ggttaccata cattggaata tctcctattc aaagacgggc agccccgcac
    13681 tgtcgatgga gcaaaataaa catgcctctg agacataaaa cttgataata gatcatgaca
    13741 aaccttgaaa cagcagacaa atgcccgctg tttcagggtt tcagagtaat tacacaatgc
    13801 gactcgcgtt attcggaaat aaattcagaa aaccaataaa atgatatgaa gcaatcttac
    13861 ctgttaacat cctcgctatt cctgctcttt gcatgcgcag cttgtgaaga ggacgataaa
    13921 atggatatgg ataaaataga tgtcccgaac ggatatgcgc tgtcagcagg gacttcaacg
    13981 attttcctaa actcatcggt cgcctacgat acgaacgccg actggataac aggagccaac
    14041 tcgatccgtt tcaacaacgg cgacggtctc tacgacgatg tacgcaccag caacaatggc
    14101 gacggaggcg gtctcggacc tgtttatgcc ggctattcct gcggcagttg ccatcgcaac
    14161 gcaggaagga ccaaaccgac attgtgggaa aatggcggat cgggcaacta cggtttctct
    14221 tccatgctgg tctatatctc ccgccgcaac ggtgctttct tccgcgacta cggacgtgta
    14281 ttgcacgacc aagccatcta cggcgtcaaa ccggaaggta agttgtccgt cacatacgac
    14341 aagcagactt tttccttccc cgacggagag acttacgaac tatgcaaacc caattacacg
    14401 ataaccgaat ggtataaaga cagtatcgcc ccggaagatt tgttctgcac cgtacgcatc
    14461 ccgttacgcc acgtcggtat gggacagatg atggcaatcg accgcaggga aatcgaagcg
    14521 ctcgctgcca aaagcaatta tccggaatat ggtatcagcg gacgttgcaa ctatatcacc
    14581 gagaagggtg tcaccggtgt cggcctttca ggaaacaagg cacagcatct tgacctgacc
    14641 gtcgaactgg gcttttcaag cgatatgggc gtgacaaaca gccgctatcc ggaagagatt
    14701 tgcgaagggc aggctcagat caaccaaggc agcatgatgg gactctcgta cgaccagctc
    14761 gacatatcga ccgccgatat ggaagatgtg gacctttaca tgcaaagcct cggcgtaccg
    14821 gcacggcgca acataaacga ccctcaggtc atcttaggag aacaaaagtt ttacgaagcg
    14881 aaatgccatc tctgccacgt cactacgctg cacacgcaag cgggcggttc cacactgctc
    14941 aacggcacac gtttgccatg gctcggcgga cagaccatac atccttattc tgatttccta
    15001 ctgcatgaca tggggtcgga gatcatggga gtcgggttga acgacaatta tgtcagcggc
    15061 ctggcacgag gaaacgaatg gcgtactacg ccgctttggg gtatcgggct gcaggagaaa
    15121 gtcaacggtc atacctattt ccttcatgac ggacgcgccc gcaacctgac cgaagccatc
    15181 atgtggcatg gaggcgaagg ggaagcctcc aaaaatttat tcaaacaaat gagcaaggaa
    15241 gagcgtgagg cagtgatcgc attcctcaac tccttataat ttatccataa gacaaactaa
    15301 aatgaaacaa ctgataatca caattgcagc attattacta ttgccgttgg ccgtcatggc
    15361 ccaatatgag gaagatacgg aaaacggtgt cgtatcacta aacggcaaag aaggttttac
    15421 aatcgctacc aagaaggggg atttcgtttt caaaccttat atgttggtac agaccagtgc
    15481 taacatcaac tactacgacg atgaagggct ggacccggcc tacaatcagg acaatataca
    15541 caacagcggt ttctcgatcc cttatgccat cctcggtttc acgggcaagg cattcgaccg
    15601 ggtgacattc aacctctcca tcaatgctgc cggaaacgga ggaaacatcc ttcaacaggc
    15661 ttggttcgac gtagagataa aaaagagttt tgccatacgt gttggcaagt tcaagactcc
    15721 gttctcgcac gcttacctga ctacgctggg cgagacgtta atgccgacac tgccgacatc
    15781 gctcacctca tccgttatcc tgccttattc tcttaatgcc gtgacaccga acatcggcat
    15841 gggattcgac ctcggagtgg aagtgcacgg attggtaaag gataagttcg gctacgaagt
    15901 tgggattttc aacggaacgg gaagctccgt caacgtggca tccaaaacgt tcagcgacga
    15961 ctggcatatc ccgtcattgt tgtatgccgg ccgcatcacg tacatgccga aaggagttat
    16021 gccgtccaac cagggcagcc cgaaccgttt gaaggaagat aagatgctgt tcggtctttc
    16081 cacttcattg aatgtggaga gcgaaagcga aagtacgaac gatttccggg caggagcaga
    16141 attcgccatg ttgaagaatc gcctgtatct cggcgctgaa atctattata tgaatgt
//
