LOCUS       c00166_gnlPro..        13406 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IJPELBLC_166.
ACCESSION   c00166_gnlPro..
VERSION     c00166_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 09:35:40
            Original ID  :: gnl|Prokka|IJPELBLC_166
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 59108
            Orig. end    :: 72514
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13406
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[69108:72513](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13405)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13406
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13406
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             569..1456
                     /locus_tag="ctg166_42"
                     /transl_table=11
                     /translation="MNNIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGKDELGNEILNVFNEKKLKTQIEQVDYPTGTVQVTLDNEGVPCYEIKEGVAWDNIPFT
                     DELKRLALSTRGVCFGSLAQRNEVSRATINRFLDTMPDIDGQLKIFDINLRQDFYTKEV
                     LRESFRRCNILKINDEELVTISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGINGSYV
                     FTPGVVSFQETPRVPVADTVGAGDSFTAAFCASILNGKPVPEAHKLAVEVSAYVCTQSG
                     AMPELPQVLKDRLM"
     CDS             1879..4716
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 61.6; E-value: 2.8e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg166_43"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.2e-19, bitscore:
                     61.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRMMGYTKWIAVLLCLLGMTACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDEGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNFPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKVGREKEMIFVGIDALPGKGNGLEMVLDSVLNATFIYPTNGDKVMQLAMN
                     ILEKKPYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRAKNRLNKELSEQKKQLEEQRDKLEEQRDQLEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADHTLSGDQH
                     RMLMLIQRNVNILLRLVNQILDFRKYENGKMEYTPVQVDVLSSFEGWNESFLAAARKKH
                     IHFSFDNMPDTDYHTLADMEKLERIYFNLLSNAFKFTPENGKITVRLSSLMKEDTRWIR
                     FTVANTGSMISAEHIRSIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTISVESDEKQG
                     TVFTVDLPVQTCETILAEDSLKSSISAVPLNPASPGSPASSDLNETLAAEEEELEKGYD
                     SSKPSVLVIDDNADIRSYVRGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGI
                     DGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRN
                     LIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGLS
                     RVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYR
                     EQFGESPTDLLKRKG"
     CDS             complement(4797..6185)
                     /locus_tag="ctg166_44"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLFGV
                     FAFSSCEKNLYDESKQPEKEIQVKDLDIPAGFQWKLTQVAAGTVAATTPTMVSFFLDEA
                     CSKKEKIADIPVDTEISSLPLSIPTYVNTLYAQYKTSTNETKKVAIPVNADRSFSLNIA
                     NDAKSKSNTTRSITRGHDIEDDIQLSKGVIFHPKDGWGTIMFEDQFPSLGDYDFNDFVV
                     NYKVQFQGIRKVDKKYTAQYIQIGLRLKAIGGIFPYSPYLRLKEIDSDEVESIEVYETK
                     NVIPAIDGVELVPNKHLIIDYSPLIKNLAKPAGSQYYNTEKNALIATSDLPEINILITL
                     KKRKEVKEILEGDEFDLYLKRNDSGTEIHMNGIEPITYQYPFNDKNLLPIYTNGDEEDD
                     NYYFSAGRLIWGLRVPGNAAHAIEKANFLEAYKGFAKWAQSSGKNEQNWYNQGNADKSL
                     LIHN"
     CDS             6269..6607
                     /locus_tag="ctg166_45"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVFTYGGIAALLGMPQ
                     CSRMVGRALKQISDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVSE"
     CDS             6914..8140
                     /locus_tag="ctg166_46"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGHEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIDTI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             8137..8961
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg166_47"
                     /sec_met_domain="BPD_transp_1 (E-value: 6.9e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMVINWMMVHFSTFFDAVNAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             8982..9848
                     /locus_tag="ctg166_48"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAILLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(10001..13405)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_49"
                     /sec_met_domain="PFOR_II (E-value: 2.6e-18, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.2e-70, bitscore: 226.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 4e-31, bitscore: 100.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.8e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.1e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.7e-08, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.2e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 6.5e-25, bitscore: 78.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLL
                     LMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVM
                     DLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALN
                     PMKPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAED
                     AERVIIAMGSVTEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVL
                     DRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMP
                     KNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTD
                     KHCQAYFSYDSKKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLR
                     KNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQS
                     AFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANL
                     PDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTAKYEKRGVAAFVP
                     EWNPENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVL
                     DCLGCGNCADICPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVK
                     NSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTN
                     ENGHGPAWANSLFEDFCEFGLGMELANEKMRARLVKVMNEAIAADCTPAEVKELFAEWI
                     NNMLDADKTKELAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGY
                     GGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMAT
                     TYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEK
                     AVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEE
                     LFKAAEENAKWRYNSYKRLARENWGAE"
ORIGIN
        1 aaccgtttat cctgctttct ttcatcggta tcatgtgtca cgttggaatt gatgtgggaa
       61 caaataccac tgcccccaag attttgatgg aacgtctcgg catgggcctt gatgatgcgg
      121 cttttgcaac aagcctttat ttcatcttcc gtacggcagg ctgcttcctc ggttctttca
      181 ttttacgtaa gatgtcaccg aagtctttct tcggcattag cgttgtgatg atgctgatag
      241 cgatggcagg tttgtttata ttccatgaca agacaatgat ttatgtatgt atcggtctga
      301 ttggtttcgg caattccaat gtgttctccg tagtcttctc gcaggcattg ctttacctgc
      361 cgggtaagaa aaatgaagtt tccggtctga tgattatggg actgttcggc ggcacggtat
      421 ttccgttggc tatgggagta gcatccgatg ccatgggaca gagtggggca gtagccgtaa
      481 tgacagtggg cgtgctttat ctcttgttct atacgttccg tattaaaaaa taattttata
      541 actttggaaa caataaaatc cgtagatcat gaataatata atcgtaggaa tgggcgaggc
      601 actttgggat gtgttgcccg aaggaaagaa aataggtggt gctccggcaa actttgccta
      661 tcatgtatca cagtttggtt ttgacagtcg cgtggtgagt gccgtgggca aggatgagtt
      721 gggaaatgag attctgaacg tattcaacga aaagaaactg aaaacgcaga ttgaacaagt
      781 ggattatcct accggtacgg tacaagtgac actggataac gagggtgtac cttgttacga
      841 aatcaaagaa ggcgtggcat gggataacat accttttacg gatgaactga aacgtttggc
      901 attgagtacg cgtggcgttt gcttcggttc cctggctcaa cgtaatgaag tgagccgtgc
      961 cactatcaac cgttttctgg atacgatgcc cgatatagac ggacaactga aaatctttga
     1021 tattaatctc cgccaggact tctacaccaa agaggtattg cgcgaatctt tccgccgttg
     1081 caacattctg aagataaacg acgaagaact ggtgaccatc agccgtatgt ttggttatcc
     1141 cggcatcgac ttacaggata aatgctggat cctgttggca aaatacaacc tgaagatgct
     1201 gattctgact tgcggaatta atggcagtta tgtgtttacc ccgggtgttg tctctttcca
     1261 ggagacaccg agggttccgg ttgccgatac ggtgggggca ggtgattcct ttacggctgc
     1321 tttctgtgct tccattttga atggaaaacc ggttcccgaa gctcacaaac ttgctgttga
     1381 agtttctgct tatgtctgca cgcaaagcgg tgcaatgccc gaacttccgc aggttttgaa
     1441 agacagacta atgtaattgt ttgatggaaa gtaagtatag aggtatatct cattcgtggg
     1501 aatatacctc ttgttctttt tgcatgattc gtatgatatg agaggtaggg gcataaaaaa
     1561 aggagcaacg ccttgctcca acctttgtta accttaaatc taatactatg aaaaacacat
     1621 tgcaaagata cggacttctg ctaaatctgc aaataatcca aataaaaaga gatgttttat
     1681 aacatttatt gagtgtttgt cttacgcttt atacttttgt taataatttc cggttgaata
     1741 ttgggaactg ttttgcattt ctttggaggg taatgatgag aataattggg tgatagatag
     1801 catactcaca gttttatttc ttatttttgt tctcaatcgt ctatttaggc catagaaaga
     1861 aatacgaaaa aaatgagaat gattagaatg atgggatata cgaagtggat agcagtcttg
     1921 ctctgtcttc ttggcatgac ggcttgtcgg caggatgcac cgcgtttccg tatcggggtg
     1981 gcgcaatgca gcgatgactc ctggcggcat aagatgaatg atgaaattct ccgcgaagca
     2041 atgttttatg atggagtatc ggttgaaatc cggtcggctg cggatgataa tcgtaaacag
     2101 gcggaagacg ttcattattt tatagatgaa ggggttgact tattgattat ctctgccaac
     2161 gaagcggccc ccatgactcc gattgtagag gaagcctatc aaaagggaat acctgtcatc
     2221 ctggtagacc ggaagattct ttctgataaa tatactgcct atatcggtgc cgacaattat
     2281 gaaataggac gtgcggtagg caattatatt gcgtcaagcc tgaaaggaaa agggaatgtg
     2341 gtggaactta ccggactggg tggctcaact cctgccatgg aacgccatca aggatttatg
     2401 gctgctatca gtaactttcc ggatatcaaa ctgattgata aagcggatgc tgcgtgggag
     2461 cgtgaaccgg cggaagtgga aatggatagt atgctccgtc ggcatccgaa gatagacgcc
     2521 gtgtatgcgc ataatgaccg tattgctccg ggagcttatc aggctgcaaa gaaagtggga
     2581 cgggagaagg aaatgatttt tgtcggtatc gatgctctcc ccggcaaagg taacggattg
     2641 gaaatggtgc tcgacagtgt gttgaatgct acttttattt atccgaccaa tggcgacaaa
     2701 gtgatgcaac tggcaatgaa tatccttgag aaaaagcctt atccccggga aacggtcatg
     2761 aacactgcgg tggtcgaccg tacaaatgcg catgtcatgc aacttcagac gactcatatc
     2821 tcggaactgg atcagaagat tgaaacattg aacggacgta tcggcggata tctgtctcgg
     2881 gttgctacac agcaggtggt gatgtatggc ggtttggtca ttcttctatt ggtggcaggc
     2941 ttattattgg tagtctataa atctctccgt gctaaaaatc gtctgaacaa ggaactttcc
     3001 gagcagaaga aacagctgga agagcagcga gacaagttag aggaacaacg cgaccaatta
     3061 gaagaacagc gggacaaact ggaagagcaa cgggatcagc tcatccagct ttctcatcaa
     3121 ctggaagagg caacgcatgc caaactggtg ttcttcacaa atatatctca cgatttccgt
     3181 actccgctta cattggttgc cgatccggta gaacatttat tggccgatca tacactaagt
     3241 ggagatcagc atcgaatgtt gatgctgatt caacgaaacg tgaatatcct cttgcgtctt
     3301 gtcaatcaga ttctggattt ccgtaaatac gagaacggta agatggaata tacacctgtt
     3361 caggtagatg ttctttcctc ttttgagggc tggaacgaat cattccttgc agcggcccgg
     3421 aagaaacaca ttcatttctc ttttgataat atgccggata cggattacca tacattggcg
     3481 gatatggaaa agttggaacg tatttatttt aatctgcttt ccaacgcgtt caagttcaca
     3541 ccggaaaatg gaaagataac ggttcgttta tcttccttga tgaaagagga tactcgctgg
     3601 attcgtttta ctgttgccaa taccggttca atgatttccg ccgaacatat tcggagcatt
     3661 ttcgatcgtt tttataaaat agacatgcac catgccggtt cgggaatcgg acttgcattg
     3721 gtcaaagctt tcgttgaatt gcataaaggt acaatttctg tggaaagtga tgaaaagcag
     3781 ggcactgtct ttaccgttga tttaccggta cagacttgtg aaactattct ggccgaagat
     3841 tctctaaagt catcaatctc tgcagttcct ttaaatcctg cttctcccgg atctcccgcc
     3901 tcttccgacc tgaatgaaac tttagctgcc gaagaagagg aactggaaaa aggctatgat
     3961 tcttccaagc cttccgtttt ggtaattgat gataatgcag atatccgttc gtatgtacgc
     4021 ggattactcc ataccgatta tactgtaatt gaagcagcag acggttcgga gggcatccgc
     4081 aaagcaatga aatatgtccc ggacttgata atctctgatg tgatgatgcc cggtattgat
     4141 ggaatagagt gttgccgtcg tctgaaaagc gaactgcaaa cctgccatat ccctgtcatc
     4201 ctattgacag cctgttcttt ggatgaacaa cggattcagg gatatgacgg aggtgcggat
     4261 tcttatatct ccaagccctt cagttcgcaa ttgctgttgg cacgcgttcg taatctgata
     4321 gattcacatc gccgcctgaa acagttcttt ggtgacggac aaacgttggc gaaagaggat
     4381 gtctgtgata tggataaaga ctttgtggaa aaattcaagg ctttgattga agcaaagatg
     4441 ggagattcaa atttgaatgt agaagatttg ggtaaggata tgggattaag tcgtgtgcaa
     4501 ctctatcgca aaataaaatc cctgactaat tattctccga atgaattgct tcgtatcgct
     4561 cgtttaaaga aagctgcttc cttgcttgct tcgtcggata tgacagtggc agagattggt
     4621 tatgaagttg gttttagttc tccttcttat tttaccaaat gttatagaga gcagtttggc
     4681 gaaagtccga cagatttgct gaaaaggaaa ggatagaatc aaaactattc acgtcagaat
     4741 acaataaatc ccggtaactt gaattttcaa tgtttaccgg gatttattga tatgtgttag
     4801 ttatgaatca ataaactttt atctgcgttt ccttgattat accagttttg ttcgtttttg
     4861 ccactacttt gcgcccattt tgcaaatcct ttataggctt ccaagaaatt agctttttca
     4921 atagcatgcg ctgcgttgcc tggtactctt aatccccaaa tcaggcgtcc tgcactaaaa
     4981 taataattat catcttcttc gtccccgttt gtatatatcg gtagcagatt tttatcattg
     5041 aatggatatt ggtaagtgat cggttcaata ccattcatat ggatttctgt tccgctatca
     5101 ttacgtttta aatacaagtc gaattcatcg ccttctaata tttcctttac ttcttttctc
     5161 ttctttaggg tgatcagaat attgatctcc ggtaaatcac ttgttgctat taaagcattc
     5221 ttttctgtat tataatattg gctgcctgca ggtttagcca gattcttaat taaagggctg
     5281 taatcaatga taagatgttt attggggaca agttctactc cgtcgatcgc aggaatcacg
     5341 tttttagttt cataaacttc tatactttcc acttcgtcag aatctatttc tttcagtctt
     5401 aaataagggg aataagggaa tattcctccg atagctttta gacgtaatcc tatttgtata
     5461 tactgcgcag tgtatttttt gtcaaccttt ctaatacctt ggaactgcac cttataattg
     5521 actacaaaat cattaaagtc ataatctcct aatgatggaa attggtcttc aaacatgatt
     5581 gttccccaac catctttggg atgaaaaatg actccttttg acaattggat gtcatcttct
     5641 atatcatgcc cacgagtgat tgaccgggtg gtgttagatt tggatttggc atcattagca
     5701 atgttcagtg agaaacttct atctgcattt acaggtatgg ctactttttt tgtttcattg
     5761 gtgctggttt tgtactgggc atacaatgta tttacgtagg ttgggatgct caaagggaga
     5821 cttgaaattt ctgtatctac aggaatgtcg gctattttct cttttttact acatgcttca
     5881 tctaaaaaga aggaaaccat agtgggggta gtagcagcta ctgttcctgc ggctacttga
     5941 gttaatttcc attgaaagcc tgcgggtata tccaggtctt ttacttgaat ttctttttca
     6001 ggttgcttgc tttcatcata aaggttcttc tcacaggagc tgaaagcgaa tactccaaat
     6061 aaacaagaag cgaatagaat tgtcttcttt ttcataacag cagtgcttgt tttgttaata
     6121 ataggattgc ttttaatggg tacaaaggtc gggattattt gtaaataaag caaataaagt
     6181 tgcatatttt atttgaaatg cttttattat ttgcaaattc ttttcttttt atctagtttt
     6241 ggaactgaaa taaattaatg tttgagtgat gaaagattat aaagtagaca aagcgagtct
     6301 ttccgcatcc ttttgtcagg aggtgtatca ggttgttcgg gaaattccgg taggtaaagt
     6361 ttttacctat gggggaattg ccgcattatt gggaatgcct caatgttccc gtatggtggg
     6421 gcgtgctttg aaacagattt cggatgattt atctgcgcct tgtcaccggg ttgtcaatgc
     6481 atcgggacgc cttgttccgg gttggacaga gcagaaacaa ctcttgttgg aagaagggat
     6541 ctctttcaag caaaatggat gcgtagactt gaaaaagcat ctttggaatt actccgtatc
     6601 tgaatgaaat ttgcatattt aatctatttt ccttaccttt gtgccaacaa tatgcaagaa
     6661 cagactgtta tttatttatg aaaatactgt tttctactgt tcattgagag gataatctta
     6721 tcaaattcta ttccttttaa actactcagt ctgttttctt taaccattta aaaaacgtcg
     6781 gatcgtcatg ttgtcatgtt gtcatgtgac atgactgaac catgcgaaca ttcaacttgt
     6841 ttatcgtaag tgagaatgag gaacgcagca gttgaaaaca aaacaactat tataatctaa
     6901 accaatatat tatatgagta aaatagaaat aaaggatttg taccttatct ttggtcacga
     6961 gaagcagaaa gcactcaaga tgttgaaaaa agataagagt aaagaggaaa ttctgaaaga
     7021 taccggttgt acggtaggag tgaaagatgc caatctttca attaatgaag gagagttttt
     7081 tgtgataatg ggactctcgg gaagtggaaa atcgacatta ctgcgttgta tcaatcgtct
     7141 gatacgtcct actgccggac aagtacttgt aaacggagta gatatatcta aaatatccga
     7201 aaaagagtta ttgcaagttc gccggaaaga gttggcgatg gttttccaga atttcggtct
     7261 gttacctcac cgttccgtat tgagcaatat cgcgttcggc ctcgaacttc agggagtgaa
     7321 gaaagaggaa cgtgagaaga aagcgatgga aagtatgaag cttgtcggat tgaaaggata
     7381 tgaaaatcag atggtaggcg agctttccgg tggaatgcaa cagcgtgtcg gactggcccg
     7441 cgctctggct aataatcccg aagtacttct aatggatgag gctttctctg cactcgatcc
     7501 tctgattcgt gtgcaaatgc aggatgaact gttggctttg caatcgaaga tgaaaaaaac
     7561 aattgtcttt attacccatg acttgagtga agcgattaaa ctgggcgacc gtattgccat
     7621 tatgaaagac ggagaggtgg tgcaggtagg tacttcagaa gaaatactga ccgaaccggc
     7681 taacgattat gtagcccgtt ttgttgaaaa cgtggacagg agtaaaatta tcaccgcttc
     7741 ttctttaatg attgacaaac cactggtggc ccgtctgaag aaagagggac ctgaagtatt
     7801 gattcgtaag atgcgtgcga agaatatcac cgtattacct gtcatagacg ccgatgataa
     7861 actggtcgga gaagtacgtc tgaacgacct gcttaagtta cgtagcagac aggaaaaatc
     7921 cattgatacg attgtgcgta ccgaggtgca ttctgtattg gaggatacag tgttggagga
     7981 tatacttcct ttaatgacaa agagcaattc gccggtatgg gtgattgatg agacgcatga
     8041 gtttttaggg acaatcccgc tttcctcctt aatcatcgaa gtgacgggga aagataaaga
     8101 agaaataaac gaaataattc aaaacgcaat agatttatga taaatatagg acaatatata
     8161 gagatggtca tcaattggat gatggtacat ttttccactt tctttgatgc cgtgaatgca
     8221 ggcatcggta gttttattat aggattccaa cacgtacttt ttggaatacc tttttatata
     8281 accattctag tgcttgctgc actcgcatgg atgaaggcag gacgtggtac ggcaattttc
     8341 accgcattag gattattact gatttatgga atgggatttt gggaggctac tatgcaaacc
     8401 ctggctctcg ttttttcatc tacctgtctg gctctgattg ttggtgtacc tttaggagtg
     8461 tggacggcaa acagtccgcg tgcagagaaa atacttcgtc ctgttctcga cttaatgcag
     8521 acgatgcctg cttttgttta tctgattcct gccgttttgt ttttcggatt gggagcagtg
     8581 ccgggagtgt ttgccaccat tatctttgct atgcctcctg tggtccgcct tactggattg
     8641 ggaattcggc aagttcctaa aaatgtagtg gaagcttccc gttcgttcgg ggctacccgt
     8701 tggcagttat tgtataaagt gcagcttcct ttggcgttgc caaccatcct gacaggtgtc
     8761 aatcagacaa taatgatgtc gctttctatg gttgtcattg ctgccatgat tgctgccggt
     8821 ggtctgggag aaattgtatt gaaaggtatt acccaaatga aaatcggact tgggtttgaa
     8881 ggtggtatcg cagttgttat tttagctatc atcttagacc gtatcacaca aggaatggca
     8941 ggacgaaaaa acaagaacta aacggaaagg ataaaatacg tatgagaata tataaaatag
     9001 taggaatagt attgtcagct atacttttgc tggcttcctg tactaattca gacttagaga
     9061 aaaagaaagt aaaaatagcc tatgccaatt ggttggaagg tattgccatg agccatttgg
     9121 ctaaggtggt attggaagaa catggatatg aggttgaatt gcaaaatgct gatcttgccc
     9181 ctatttttgt atctatgtca ggaaagaaat cagatgtgtt tctggatgcc tggttaccaa
     9241 taacgatgaa agattatatg gatcagtatg gagacagcat cgaatttctg ggtgaggtat
     9301 atggagaagc ccgtgtaggg ctggttgttc ctcaatatgt tacgattcag tctattagtg
     9361 agctggaagc taataaagac cgtttctctt ccgaaatagt gggaattgat gccggagcag
     9421 ggataatgaa gacgaccgat aaggccattg ctgcttatgg acttgatggg tataccctca
     9481 tgacttcaag tagttccacc atgctggctt ctttgaaaaa agcgatggac aaaggagaat
     9541 ggattgtcat cacggggtgg acaccgcatt ggatgttcga ccagtttgac ttgaaattct
     9601 tggatgatcc gaagaaagta tatggagact tggaagaaat acatgctatt gcatggaaag
     9661 gattcagtga gaaagatccg tttgctgccg aattctttgg caacattaaa ctaacgacag
     9721 aagaacttag ctcttttatg acagctatga aggatgcccg gatggatgaa gaagaaatag
     9781 cccgcaaatg gagggatgaa catcggcagt tggtggatag ttggattccg aagtcagaga
     9841 ataaatagat tggagcattg ttatttttaa ttttaaatat aaaatagaca tgaactctag
     9901 tgggaaaaag ggagtattgt ttatgttaga cagagttcat acaataaaaa aacggtaatc
     9961 ttctacaaga ttaccgtttt atatttatag ggtattacta ttattcagca ccccagtttt
    10021 ctctagccaa acgtttgtag ctgttgtaac gccatttagc gttttcttca gcagctttga
    10081 acagttcttc agcttcagca ggatattgtt tcattacaga agcgtaacga acttcaccct
    10141 tcaagaaacc ttggaaatct tcccagttcg gttctttgct atccaattgg aatgggttct
    10201 tgccttcttc ttccaaagcc gggttgtaac gccacaagtg ccagtaaccg cacttaacag
    10261 ctttttcttc ttcttcttgg ctcttaccca tacctgcttt cagaccgtgg ttgatacatg
    10321 gagcataagc gataatcaaa gatggtcccg gatatgcttc agcttcacgg atagctttca
    10381 gagtttgagc ttggtcagca cccatagcga tctgtgcaac atatacataa ccgtaagtag
    10441 tagccatcag accgaggtct ttcttacgta cgcgcttacc agcagcagcg aacttagcga
    10501 tagcacctac cggagtagct ttagaagact gaccacctgt gttagagtaa acttcagtat
    10561 ccagaacgag gatgttaacg tccttaccgg aagcgattac atggtcaaga ccaccgtaac
    10621 cgatatcgta agaagcaccg tcaccaccaa tgatccactg gctgcgtttt acaagatatt
    10681 gttgcagttc agcgatttgt ttgcagtggt tacatttatc cttgttagct tcaacaaccg
    10741 gaatgatctt agcagccaat tccttagtct tgtccgcatc cagcatattg ttgatccatt
    10801 cagcgaacag ttcttttact tcagcaggag tgcaatcagc agcaatagcc tcgttcatca
    10861 ctttcacgag acgagcacgc atcttttcgt tagccagttc catacccaaa ccgaattcac
    10921 agaagtcttc gaacagtgag ttagcccaag caggaccgtg tccgttttcg tttgtagtat
    10981 acggagtaga aggaacagaa ccagagtaga tagaagaaca tccggtagcg ttagcaacca
    11041 tttcacggtc accgaacaat tgagaaatca atttcacgta cggagtttca ccacaaccag
    11101 agcaagcgcc ggagaactca aacaacggag tagcgaactg tgagttcttc acgttagcct
    11161 tgatatcaac aagatgttgt ttagtcttca cgttttcagc acagtaagtc cagttttcag
    11221 cttgagccaa ttggctttcg aggtgtttca ttgtcaatgc tttgccaccc ttcttcggat
    11281 tacccggaca gatgtcagca cagttaccgc aacccagaca gtcgagaacg tccacctgga
    11341 tacggaatgt cataccgtcg aatgctttac ctacagcttt cagttgttcg aacttagcac
    11401 ccttctgctc ttcagcgtcg agtacgaacg gacggataga agcgtgaggg caaacgtatg
    11461 cacacttgtt acactggata cagttttccg gattccattc aggaacgaat gcagctacac
    11521 cacgtttttc gtatttagca gtaccttgat accaagtacc gtcttcgata cccttgaatg
    11581 cagataccgg caacaagtca ccgtcttgtg cattgatcgg acgaactact tcgttgatga
    11641 atgcaggatc gttgttttca gcttttgcgt catccggaag gttagcccaa gcaggatcaa
    11701 cagccaaagt cttgtattca ccaccacggt caacggcagc atagttcttg ttaacaacgt
    11761 cttcaccctt cttgccgtaa gacttaacga tgaatttctt catctgctca acagcttggt
    11821 ctacaggaat aacgcctgtg atacggaaga atgcagattg aaggattgtg ttggtacggt
    11881 tacccaaacc aatttccagt gcaatttgtg ttgcgttgat atagtataca gaaatgttgt
    11941 tctgtgcaaa atatttctta accttgttag gcaggttctt agccagttct tcaccttccc
    12001 agattgtgtt cagcaagaaa gaaccgttct tacgcaaacc acgagttaca tcgtacatgt
    12061 gcaggtaagc ctgaacgtga caagcaacga agttcggagt atttaccaga taagtagaac
    12121 ggattggatt gtcaccgaaa cgcaagtgag aacaagtgaa accgcccgac ttcttagagt
    12181 cataagagaa gtaagcctgg cagtgtttgt cagtgttgtc accgataatc tttacagagt
    12241 tcttgttagc acctactgta ccgtcagcac ccaaaccgta gaatttagct tcgaacatac
    12301 cttcgccgcc taaagcgatt tcttcttttt gaggaagaga agtgaaagta acgtcgtcta
    12361 cgataccgat agtgaagtgg ttcttcggca ttggcatagc caagttttcg aatactgaaa
    12421 ggatttgagc aggagtagta tcttttgaac ccaaaccgta gcgaccgcca acgataaccg
    12481 gagcattttc tgcaccgtag aagcagtctt taacgtcaag gtaaagaggt tcgccgttag
    12541 cacccggttc tttagtacgg tcaagaactg cgatagtctt agcagtctta ggtacagcag
    12601 ccaggaagtg tttagcagag aacggacgat acaggtgtac ggcaaccata cccacttttt
    12661 caccgtttgc taccaggtag tcgatagctt cgcgggcagc ttctgttaca gaacccatag
    12721 cgataattac gcgttctgca tcttctgcac catagtaatc gaacaaaccg tatttacgac
    12781 ctgtgatctt agaaatttca ttcatgtatt cttctacgat agcaggaact gcttcatagt
    12841 agttgttgca tgattcacga tgttggaaga aatggtcagg attttcagcc ataccacgag
    12901 ctaccggttt catcgggttc agtgcgcggg cacggaattc agccaaagct tcttggtcga
    12961 tcagcggagc aagatcatca ttttccaaca tttcaatctt ttggatttcg tgagatgtac
    13021 ggaaaccatc gaagaagttc atgaacggaa cgcgagattt gatggtagcc aagtgagcaa
    13081 caccagccaa atccataact tcctgtacag agccttcagc caacatagca aagccagtct
    13141 gacgagctga cattacgtct tggtggtcac cgaagataca caatgcgtga gaagccaatg
    13201 tacgagcaga tacatggaat acgcaaggca agaactcacc ggcaattttg tacatgttag
    13261 ggatcatcag gagaagaccc tgggaagcag tgtaagtagt agtcaacgca ccagcctgaa
    13321 gagaaccgtg aactgcaccg gcagcaccac cttcagattg catttcctgt accaatactg
    13381 tttcgccgaa gatgttctta cgtcct
//
