LOCUS       c00033_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDLCBJPM_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:52:38
            Original ID  :: gnl|Prokka|HDLCBJPM_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 79864
            Orig. end    :: 104502
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[89864:94502]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(314..1309)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_74"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 7.1e-33,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
     CDS             complement(1320..3050)
                     /locus_tag="ctg33_75"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             complement(3141..3752)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_76"
                     /sec_met_domain="CTP_transf_like (E-value: 1.9e-24,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTVSKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             complement(3737..3910)
                     /locus_tag="ctg33_77"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             complement(3907..4476)
                     /locus_tag="ctg33_78"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAQKEALKVIKEFLKKA"
     CDS             complement(4486..5358)
                     /locus_tag="ctg33_79"
                     /transl_table=11
                     /translation="MIQSMTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEK
                     EMQIRSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPA
                     DWFQTLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIA
                     NISRLLSEVEPYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKN
                     RLDNHLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQ
                     IKEQVLNVL"
     CDS             5639..6301
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_80"
                     /sec_met_domain="Peptidase_M22 (E-value: 9.7e-24, bitscore:
                     77.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGEVLFAKASFDGPSHAALLGVFVEEALSVLKKKGKKALDAVAV
                     SSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAATVNSKGDSQIVSITDDCLYC
                     AMLDARRMEVYAAIYDASLKPVRETKADIVEAGTYASYLEKGKVCFFGNGVSKCKSVIT
                     SPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFYLKEFQATVAKNKVLLAR"
     CDS             6604..6714
                     /locus_tag="ctg33_81"
                     /transl_table=11
                     /translation="MIVSIFNYHFILSYYHVVYHMLLSSCWGKISVDIIE"
     CDS             6904..7290
                     /locus_tag="ctg33_82"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             7332..9380
                     /locus_tag="ctg33_83"
                     /transl_table=11
                     /translation="MHSRDMEYIVGLLKNGKDAEAILSVRRKLNMAFLARTTDLSGKLP
                     VLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAAALPQTLLAFVGLSG
                     RSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSIISLKEPFLSRGCRM
                     SVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAPGADRNGQIATLFSV
                     ILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRYEALKKYKIDVRMAF
                     RTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMSGGVEYLDRSMIQFV
                     YKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDHFLGNLPAWDGKERI
                     RALAGRVPCDNPVWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLVGGQGCGKSTFCLNL
                     LPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVKSSHQSFLKHILQKAVVNTR
                     LPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRIDYAQPIDYDQLYAEA
                     KELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAEDIEEAKPLLASEIL
                     DMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEVDG"
     CDS             complement(10001..11197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_84"
                     /sec_met_domain="OAD_beta (E-value: 1.4e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(11202..11633)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_85"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.8e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             complement(11656..12549)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_86"
                     /sec_met_domain="OAD_gamma (E-value: 9.7e-12, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGRTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             complement(12565..14118)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_87"
                     /sec_met_domain="CT_Btheta (E-value: 1.4e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             complement(14231..14638)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_88"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.4e-27, bitscore:
                     86.7, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGIKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             complement(14783..17188)
                     /locus_tag="ctg33_89"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             17297..18229
                     /locus_tag="ctg33_90"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             18252..20081
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_91"
                     /sec_met_domain="Peptidase_U32 (E-value: 5.9e-73, bitscore:
                     237.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARAAAG
                     NSLEDIRELCEYAHLYGARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDVGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     SNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLTPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARRERQDNIRTQLSKLGNTP
                     FEASKVVVGLSENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(20299..20766)
                     /locus_tag="ctg33_92"
                     /transl_table=11
                     /translation="MKIINEALLNETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSIIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             20863..23595
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_93"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.2e-07, bitscore:
                     22.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRISFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVVHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIHLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCTFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMSEEVSMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
ORIGIN
        1 ccagtcgaag ctattgttta atgcttctac cactgctttt gttcctaaat agctgccgcc
       61 gataccgatg gcgacaacaa cttcacattt ggaacgaagt acgttagctg tattttcgat
      121 gtctgtcagt tcagcatctg taatagaaga ggggaggtgc aaccaaccta aaaagtcgtt
      181 acctgcacca ttaccatttt gtaaagtggc attacattcg tgggcctttg cagcctgagc
      241 atatacctgt tctttcgtta cggtacccag cgctttgtca atgttaagac tgatgttctt
      301 catatttaca ttattattta aatgtttcag tcaactgccg tatcgcggta gtcggcgatt
      361 tcttttcgta tagaatacta tataaagtat ccaagatcgg catgtttact ttatattttt
      421 cgtttatctc ccgaatacat tttgtcccgt agtatccttc ggcgatcatc tccatttcga
      481 gctgggctat tttgacggaa taacctttcc cgatcatggt cccgaacgta cggttccggc
      541 tgaagcgaga atatgcggtt accagaagat caccgagata taccgaatct gtcacatccc
      601 gttccaggcc atgtacggcg ttgaggaagt tacgcatctc ttcgatcgcg ttgcagatga
      661 aaactgccag aaaattatct ccgtacttca taccgtggca gatacctgcg acgatggcat
      721 atacgttttt caatacggaa gcatattcaa tacctgtaac atccttgcaa caggagttgt
      781 tcagatactg gttcttaaat acggaggaga aagctcttgc attctcgata ttagggcaag
      841 ccagcgtgat ataggacaac cgttcgagag cgatctcttc ggcatggcac ggaccgccga
      901 tgacagcgat attgtcaatc gggacattgt agtattcggc aaaataatcg gctacgagca
      961 tgttttcgtc cggaacgatt cctttgatgg ccgaaatgat gaatttgtct tgcatggagg
     1021 tcgtcacctt catcaaatgt tgtttcaaaa aaggagaagg ggtggcgaaa atcaaagtgt
     1081 ccgaatcttt gattactttg ttgatatccg tgtagaattt gattttgtca gtatcaaatt
     1141 tgacggcgga aagatagctg gggttatgtc ccaacaacag aaactcttct acttggtctg
     1201 gccgacgcat ataccagtta atactatctt gtgtagaaag tacaatcttg gccaaggcgg
     1261 tagcccagct accacctccc attattgcaa tttttccggg caacttcata gtattactct
     1321 tatttggctg cgcctgcaat ccatgcctct acttcttcgg cagtggggtt ttgcaattcc
     1381 agtttgtatt tcttattcat ttcgcagagt tcctgtctca gcttgttggg attagcatct
     1441 accaacgtgt cggttgtgag atatccggct ttatgtaaag caggaaccca tgcttcatcg
     1501 atacccagtg cgacatattt gtctgcggtg tctttcttaa ctgtcttttc cgggcgcatc
     1561 tgcgggaaga gcaacacttc ttgaatagtc gtttggccag tcatcaacat caccagacgg
     1621 tcgatgccga taccgatacc agacgtcgga ggcataccga attgcagtgc acgcaaaaag
     1681 tcctggtcga tgaacatcgc ttcgtcatcc cctttttcgc tcaggcgcaa ttgctctttg
     1741 aagcgctctt cctgatcgat cggatcgttc agctcactat aggcatttgc cacttcttta
     1801 ccgttgatca tcaattcgaa acgttcggtc aatccaggtt tgctccggtg catcttggtt
     1861 agcggactca tctcgaccgg gtagtcgata atgaaagtcg gctggataaa cgtgccttcg
     1921 cagaattcac cgaagatttc atcgatcagc ttgcctttac ccattgtttc atcgatttca
     1981 aggttcaaat ccttgcaaat cgtgcgtatc tcgtcttcgc tcttgccatt caggtcgtaa
     2041 cctgtctttt ccttgatggc atccagaatc ggcagacggc ggtaaggagc tttaaagttg
     2101 atggtcttgc cgtcgactac actttcacat gtaccgttga cggcgataca gatacgttcc
     2161 aacagctgtt cggtgaagct catcatccag ttgtagtcct tatattggac ataaagttcc
     2221 atacaggtaa attccggatt gtgggtgcga tccatacctt cgttacggaa gtttttaccg
     2281 atttcgtaga caccttcgaa acctccgacg atcaatcgtt tcagatacag ttcggtagca
     2341 atacgcagat agaggtcgat atccagcgag ttatggtgcg taatgaacgg acgtgcgctt
     2401 gcccctccgg ggatggattg caggatcgga gtttccactt ccgtatatcc agcttcgtcc
     2461 agggcggtac gcatggtctt gataactgcc gcacgtttca tgaaaatatc ctttacgcca
     2521 tcattgacca ccaggtcaac atagcgttgg cgataacgca attccggatc gttgaatcca
     2581 tcgtatgcta caccgtcttt gtatttgacg accggtagcg gcttgagtga tttggataat
     2641 accgttatct cttgtgcatg gacggaaatt tcgcccatct gtgtacggaa tacgaaacct
     2701 ttgattccga caaagtcgcc gatatcgagc aatttcttga aaacaatgtt atacagatct
     2761 ttattttctt ccgggcaaat gtcgtcacga gagatataaa cctgtattct gccttctgaa
     2821 tcctgcaatt ccatgaagga agcctttccc atgatgcggc ggctcatgat gcgaccggca
     2881 atacttacgg ggcggggctc tgcatcgtct ttaaaattct cttttatctc tttggaaaat
     2941 gcattcgtta catactcagc tgcgggataa ggttctatcc ccatctgacg taactgctcc
     3001 atgctgttac gtcttatgat ttcctgttca ctcagttcta atagattcat tacgctatta
     3061 ttttgtataa tacggcgcaa aaatacaaaa cttttcttac ttattgccta aaaacgtatg
     3121 cgactttacg ctttatgttc ttaaaaggta ttgttttgta atggaaaagg cagattacgt
     3181 atggcttcgg gcaggaagaa gcggacatct tttccggtct tgaaagcttc gcgtataaag
     3241 gttgaggata tttcgaccaa aggggcgtct acttttttta tgtgaggata ttgtgccgga
     3301 atttcaacat cgaatccttt gcgcggatag atgaagatcg gataattgga aatgatggct
     3361 tcgtattcta cccaccgggt aatatatttc caattgtccg cacccatgat gaaatagaat
     3421 tcacggtccg gataacttgc ttccaatgtc cggagtgtgt tgatggtata agtgggttga
     3481 ggaagggaaa actcgaagtc actggcgtgg aacttagggt aaccagcgat ggattttttt
     3541 accagttcat agcgaagccg gtcatccatc agttcttcct tctcttttag cgggttatgg
     3601 ggggtgatca gaaaccatag ctcgtccaac tccgtaaatt cacacaacca gttggctaat
     3661 gccagatggc cgatatgaac cggattgaat gaaccggaat aaatgccggt tttacgtttg
     3721 ctgaccgtat tttctttcag tcccgtttcc acttgatgat atttatgact tgtgcaccga
     3781 ataccaatcc ggtaccggtc gctatgatat actccttata atatagggcg gctgtacaag
     3841 tggcaagagc gacaaatgct ataccaatga atgtatatag ccatttcttg gataacttct
     3901 tgccgttcat gcttttttaa ggaactcttt tatcactttt agtgcttctt tttgtgcgac
     3961 ttccagcttg tcattcacca cgattacgtc aaatttgtcg gcaaaaccca gttcaaattc
     4021 ggctttggca atgcggcttt cgattacttc cggagcatcc gtaccgcgtc cttccagacg
     4081 actccgcaaa tcttcgatcg aggggggctg gataaagacc gaaagagcac ggtcgccata
     4141 aaacttcttg atgttgcaac ctcctacgac atcgacatcg aatataacgt tatcgccact
     4201 catcagcctt cgttccacct cgcttttcag cgtgccgtaa tatttgtcgg tatagacctc
     4261 ttcgtattcc aggaaatctc ctgctgctat acgggcacgg aattcatccg gtgtaaggaa
     4321 ataatattcc actccgtcct tttccgtacc acgtggggcc cggctggtag ccgagatgga
     4381 aaaatgcagg ttcagattct gcttcagcag gaaattgatg atagtggatt tgcccgaacc
     4441 ggacggcgcg gagaatatga tcagtttgcc agccatatat cgtttttata atacgtttaa
     4501 tacttgttct ttgatttgtt ccagttcgtc tttcatctgg acgacaagtt tttgcatctc
     4561 ggcatggttg cttttcgaac caagggtgtt gatttcacgt cccatttcct gggcgatgaa
     4621 accgagtttc ttaccttgtc cgtgtccgct ctccatcgtg ctgatgtaat atttcaggtg
     4681 gttgtccagg cggttctttt cctcgtttac atccagtttt tcgatataat agatcatctc
     4741 ctgttcgaac cggttcttgt cgtagtcctg tccggcaatc ttttcgagat tgtccatgat
     4801 acgggctttg attttttcga tccgctcctt ttcatacggt tctacttctg aaagcaggcg
     4861 ggagatattg gcaattttct gttcgaacaa cttttgtaac atggcgcctt cctgaatacg
     4921 gaaatcgcaa aggtgcccta tggcctcttt gatcgctttc tcaaccacat tccattcctc
     4981 ttcgtttact tcctgggcct ctgtcttgat cacgtccggc atgcggagca gggtctggaa
     5041 ccagtcggcg ggaagtccga tgttcaggcg gtcggcaata tctttgattt gattgtaata
     5101 gttttctacc gcagccaagt tgatctgtgt gggcgtgtct ttaccgatat attcgacaaa
     5161 tatattaaat tcgacttttc cacgttcaag cgactggagt aacaaactgc gtatttgcat
     5221 ttctttttct ttgtagatgg aaggaatgcg ggtcgacaaa tccagttgct tgctgttcag
     5281 agcttttatt tctacggtta cttttttaga aggaagttcg gctgtaacct taccgaatcc
     5341 agtcattgat tgtatcattg ttctaaaaat ttgtgcaaag atagctaatc aattgataat
     5401 tgacaattga cgattgacaa tataattgag aaaaagccga aaccatccgt gtcagcctta
     5461 ataaaatcgg ttttgatcat gagattacag ttatgtttta tacttttgca tccattatca
     5521 accgattggc ttttgacaca tattttaatt gtcaattgtc aattgtcaat tgtcaattaa
     5581 aatgtcttgt atattaaata tcgaaacatc gacttctgta tgctctgtag cgttgtctat
     5641 ggatggtgaa gtcctttttg cgaaggcctc gttcgacggc ccttcgcatg cagccttatt
     5701 aggcgtattt gttgaagaag ctctttccgt attgaaaaag aaggggaaga aagccttgga
     5761 tgccgtagcg gtcagtagcg gtcctggttc ttataccgga ctccgtatcg gagtgtctgt
     5821 cgctaaaggt ctttgctttg gtttcggtat tcctctgatc ggcattcata cgttggacat
     5881 catggctgct actgtcaaca gtaagggcga ttcgcaaatc gtctctatta ctgatgattg
     5941 cctttattgt gctatgttgg atgcccggcg tatggaggtt tatgccgcta tctacgatgc
     6001 ttccttaaag cctgtccgcg agacgaaggc cgatattgtg gaagccggta cgtatgcttc
     6061 ttatctggaa aaagggaaag tttgtttctt tggcaacggt gtttccaaat gcaaatcggt
     6121 catcacttct ccgaacgcca tctttatcga ggacatccat cctcttgccg taaacatgat
     6181 tccgctctcg gaacaagctt ttgccgccgg caagtttgaa gacaccgcct atttcgaacc
     6241 gttctacctg aaagagttcc aggcgacggt tgcaaaaaat aaggtgcttt tagctcgatg
     6301 atgtagttgt gtgctatgtc ggaatggcac gtttgtcgaa atttttatgt aagtccggtc
     6361 aatcggaaaa gaacttagat atgcaaaatc gtcctgtttc ttgtgtttga tagctgtaat
     6421 gtcaaacatg gaaacgggac gatgtgttat ttagggttgc catccatgta agtcttcctc
     6481 ctgcaagcaa tataaataag ctgctgtaaa catccaccta ttatatacat acgatttttt
     6541 ttaaatccaa ctatcatact atcatattta catataaata tctgtatatt agtttataaa
     6601 aatatgatag tatctatttt caactatcat ttcatactat catactatca tgtcgtatat
     6661 cacatgcttc tgtcttcgtg ctggggaaaa ataagtgtag atataattga ataaagtgct
     6721 gtaaatattt gtattataga tgttttattt gtatatttgt aataagaaaa gaagcccgtc
     6781 atccgggtgt cggaaggggt gagacccggg tgttgatacc gttcagatgg gggtgtcaaa
     6841 agtgttaaaa tgggcgtctt gagaagaata tctggttgtt taatattaaa aatactgtta
     6901 tttatggcac attactatgt agtccggcaa aaactggaca agacgggagc ggaagataaa
     6961 gtacgctatt atggtgttcc ggttacgtgc gggcgggttt caacgaaaaa gctggctgat
     7021 ttggttgccg atcgttgctc gttgagccga ggtgatgtgt tcgcttcggt ttgcgagatc
     7081 ggagggatga ttcttgaatt gttgaaagac ggctattccg tggagttgga cgggttgggt
     7141 gatttttatc tttcggcagg gagcgaaggc ttcgaagatc cgaaaaaatg tactccccat
     7201 cgggtgaagg cgcgtcgtgt ctgtttcagg atggctccct gtgtgagaaa gagcatgaaa
     7261 tttgtcaaat tcgaaagaaa tccttggtaa tgcaaatcac atattacagg cataaaaaag
     7321 gcgtgttgcg gatgcactcg cgtgatatgg aatatattgt cgggttgctg aaaaacggca
     7381 aagatgcgga agcgatactg tcggttcgtc gaaaattgaa tatggcgttt ttggcacgaa
     7441 ccacggattt gtccggaaaa ctaccggttc tggcttttgg ctcgacgttc aagaagaatg
     7501 gcgatggaat acagttgagg cgttataacg ggtatgtctt gttggaagtg aacggcttgg
     7561 aaagccagag tgaggcggag gccgtccgcc gtgaagctgc cgccctgccg cagaccttgc
     7621 tggcgttcgt cgggctgagc gggcgttcgg tcaagatcgt ggttcctttt gtgctgcccg
     7681 acggctcgct gccgaaaaaa gaggagcagg cccgtatgtt tcatgctgcg gcttatcagc
     7741 tggcggtgcg gcattaccag ccgcagttgg gcagcattat atcgttgaaa gaaccgttcc
     7801 tgtcgcgggg gtgccggatg agtgtggatc cggacgccta ttacaatccg gatgcggtgg
     7861 cgatccggat cgagcaacct ttgcagatgc cggacggggg tgacttgaag atcgtgcctt
     7921 ctccggttcg ggatccgttg gagatgatgg ctccgggagc ggatcggaac gggcagatcg
     7981 ccacgctgtt cagtgtcatc ctgatggaga tgacgcgtcg gttttcagaa agcccggaag
     8041 atgatatcca actgctgttc atcgacttgg cgcaggcttg ctgccggctt ggaataccgg
     8101 aggaagaggc ggtgggctgg acattgcgct atgaagcttt gaaaaaatat aagatagacg
     8161 tccgtatggc tttccgtacg gcatatacgt tggagaatgt ttcaaaccgg gcggagccgc
     8221 tctcttccgt cccgccatcc atgtcgttag tgttgcggtt ggacgagttt atgaaccggc
     8281 gttatttctt ccggacgaat gagatgagcg gtggagtgga atatttggac cgttcgatga
     8341 tacagttcgt ttacaagcct tatacgacga aagtccggaa ttccatttgc ttggaagccc
     8401 agcaggaagg gttgaatgta tgggacaagg atatcgaccg atatgtcaac tccgatcgtg
     8461 ttccgatata tcatcctatc gatcattttc ttgggaatct tccggcttgg gacggaaaag
     8521 aacgcatcag ggcattagcc gggcgtgtcc cttgtgacaa tccggtatgg ggagatttgt
     8581 tttaccgctg gttcctaagc atggtggcac attggatgga actggattcg gaacacggga
     8641 atagtacgac acctctgttg gtcggtggcc aagggtgtgg gaagtccacg ttttgcttga
     8701 atttgttgcc accagtgttg cgtccttatt atacggacag tatcgatttc ggcaatcgcc
     8761 gtggggcgga gttggctttg caccggtatg cgttgattaa tatcgatgaa tttgattcag
     8821 tgaaaagttc tcatcaaagt tttttgaagc atatcctgca aaaagcggtt gtgaacaccc
     8881 gtttgcctta tcagagtgcg agccgtaact tgcgtcgcta tgccacgttt atcgcgacca
     8941 gcaacaatta tgatttgctg acagatccga ccggtagccg ccgtttcatt tgcgtggagg
     9001 tgaaggggcg gatcgattat gcccagccga tcgattatga tcagttgtat gcggaagcga
     9061 aagaattgtt gaggcgtggt gaacgttttt ggtttactcc ggaggaagag gcgctgatca
     9121 ctgaaaacaa cagggatttc cagcagcagc cggctgaaga gcaactgttc ctgcgttatt
     9181 tcaagatcgc ggaggatatt gaagaggcaa agccgcttct ggcgtccgag atactggata
     9241 tgatcgcgga gaaacaaccc ggttttaaca ttacaaaaac gatgatcctt aatttcggca
     9301 agcttttgaa gcggaatagc gtgccgaata agcggacgat gagggggact tgttattatg
     9361 tggaagaggt agatggttga tatataattg attgactaat tttatgtatg atggtatgat
     9421 agtagccatg acagttattt tgcgaactgt catggctatt ttgtgttgat agatagtggg
     9481 ttattgccaa ttatgatggt atgatagttg gatcgtctat ttccaattgt atttgtaagt
     9541 gaagaaaaaa acattctttc taaaatattt actcagttaa ataaagaaca aaagtaagga
     9601 acggttaaac caaaaaaggg ggtgtcttgt ttaatcttca aatcaatatt gaagaataga
     9661 catgagacga aagaatacga atgtactgct ggtctttggt gtggtgatcg cgattatcct
     9721 gttaatgatt tggttgtttt tggggacaac attggaacag gaggcaaatc cagagacaga
     9781 tccgatgacc gtcgaacaaa atatctgata aggtcggata taaaaaggga ggctgtgtcg
     9841 taaatagttt tttatgatac agccattaat atacttctga tgaatcgttg tgcgcatata
     9901 caaacttacc caagaatacg ttaaagtccg taaacttggg taatttttta tatttggaga
     9961 tgacttggag ttcagctcct ttttatgtag aataagtgaa ttatcctaag aatcccaaca
    10021 ggataccggc tgctacggca gaaccgatta cacctgctac gttcggaccc atggcgtgca
    10081 tcaacaggta gttggtcgga tcatattcca gacctacgtt ctgagagata cgggcagagt
    10141 cgggcacggc agacacaccg gagttaccga taagcggatt gatcttattg ccttctttca
    10201 agaacaggtt gaagaacttc acgaacagga tacctgcaca agttgcgatc acgaatgaca
    10261 acgctcccaa accgaagatc ttgatggagt tcaatgtcag gaactgagtt gcttgagtag
    10321 aagcacctac cgtaatacct aacaggatcg tgatcgtatc aatcagcgga ccacgggctg
    10381 tttcagccaa acgacgtgtt acaccacttt ctttcaacaa atttccgaag aacagcatac
    10441 ccaacagagg cagaccggaa ggaactagga agcaagtcag caacaggcct acgatcggga
    10501 atacgatctt ttccgtggaa gaaacggctc tcggcggttt catacggatc agacgttctt
    10561 tctgagtcgt cagcaggcgc atgaacggag gctggataat aggaaccagc gccatataag
    10621 agtatgccga tactgcaata gcacccatca agttcggagc taacttggaa gaaaggaaga
    10681 ttgctgtcgg gccgtcggca ccaccgatga taccgattgc accggcctgg ttcggttcaa
    10741 atcccatttg aagagcgatg atatatgctc cgaaaatacc gaactgagcc gctgcaccga
    10801 tcaacatcag tttaggattg gagatcaatg cggagaaatc ggtcatggcc ccgataccga
    10861 ggaagatcaa cggcggatac catccggagg ttacaccctg gtagaggatg ttcagcacag
    10921 aaccttgttc gtaaataccc acctgcaatc ctgcatcttt gaacggaatg ttaccgatca
    10981 ggataccgaa tccgataggg ataaggagca taggctcgaa ttcatattta atagccagga
    11041 agatgaacaa cagaccgaca aggatcatga taaggtgacc cggtgtcgcg ttgtagactc
    11101 ctgtataagt gaggaacaac tccaagtttt ctcccaagaa ctggagaaag ctttcatgag
    11161 ccgtacctgc tgcctgtaat aatactgatc ctaacataat attatcctat tacgacgagg
    11221 tcagcacctt ccagtacgga atcccctttg tttactttta tttcaatgat tttgccgtca
    11281 cggtcggcgt tgatgttgtt ttccatcttc atggcttcga ggacaagtag attctggcct
    11341 ctcttgacag tatcaccgac tttacagtta acctgcagga ttacacctgg cagcggagat
    11401 ttgacagcgc ccttggtggt tgaggctgcc ggacgggaaa taaccggttc gccacttgcc
    11461 gttgtaggag cttgagccgg gcgtttcagt gtaaccatct gtttttttgc cggtttctcc
    11521 atttttacct gatagggagt accgtttact tctacttcag cgatgtcatc cactaccgag
    11581 ctgatatgta ctttatatac gttaccgtta atagtatatt taaaactttt cattcttgtt
    11641 tgtttttaga gataattact ttttgggaac ttcacgcaga ccgtaaatct tggaactcca
    11701 cggagaataa gatctttgaa ccttgcggat cgtcagaacc gtatgttcga tgtcgtggtt
    11761 gtcgtcgctc atttcgtata gagccgcacc gatagccgca aagatttccc cggattcctg
    11821 acctgcattg tctgcaataa cagccgctcc ggccgctttc tgtgcattgc gtttgctggc
    11881 cgcgatcgag agctttccga tttgtttaaa gatgatgaac aacaggaata atccggagaa
    11941 cacaactgcc atggcagtca gggtcatacc gataccccaa gaatcatttt ctttaaagtt
    12001 ctcgattttc tcgttagaat ccaatgttac gttattggtg ctgggtgtaa cttttgtcag
    12061 agctgtccat tctccttgtc cgtctaaagt tctaccatag ctgacatctg ctttttgtga
    12121 agcagggata acgatctcat cgatcagagt tctaccgtct gcatcgtata acgcaatgta
    12181 attttctttt gatgggtcga gcgtgaaatt gacatggaat gttccccgat ccggttctcc
    12241 gtctgcccag aacaaagtgt gctggcgagg aggaattact gttagaacgt cgcccttcgg
    12301 aatcggatac tttttcgggt tgctcttgtc attagtcaag tagcaaccgg cgatattgac
    12361 cgaaccggcc gaattgttga acaattcgat ccaggcatgg cgtttgccgt aatcatcaac
    12421 aaagttatct tcgttgatga ccagcacttc atttattcgc atggaggttg cacgctgtgc
    12481 ttttgccccg aatgaaacga gcaacgcgaa cagcagcaat acccctattt tcttattaat
    12541 catattcatt tcctgtttta agaattatag aggcagattg tcatgtttct tggcaggatt
    12601 gcttaacttc ttggtctgca attgttgtaa agcacgaata atacggaaac gagtgttacg
    12661 aggttcgata acatcgtcga tatagccata ttgagctgca ttgtatgggt ttgcaaatgc
    12721 ttttttgtat tcggcttctt tttctgcagc gcaagctttc ggatcttccg aggcagccac
    12781 ttcttttgca aagatcactt ctacagcgcc gcttgggccc ataactgcga tttcggctgt
    12841 cggccatgcg tagttcatat cgccacgcag atgtttggag ctcatcacac aataggctcc
    12901 accgtaagat ttacgcaatg ttacagttac tttaggcact gtggcttcgc cgtaagcgta
    12961 aagcaatttg gctccgtgca ggataacacc gttgtattcc tggcctgtac ccggtaagaa
    13021 tcccggtacg tcaaccaatg taaccaaagg aatgttgaaa gcatcgcaga aacggacgaa
    13081 acggcctgcc ttgcgggagg cgttgctgtc cagacagcct gccattactt tcggctggtt
    13141 ggctacgata ccgacagtct ggccgttaaa acgggcgaaa ccgacgataa tgttcttggc
    13201 atagtcggca tgtacttcca gaaattcgcc gttatcgatg atggttccga taacttcata
    13261 catatcgtaa gcctggttag gattgtcagg gatgatgtcg ttcaggttgt catccagacg
    13321 gtcgatcggg tctttacatt cgatcagagg agtttcttcc aggttgttct gcggcaggaa
    13381 gctgatcaat ttgcggatca actgtaaacc gtcttcttcc gtatcgactg cgaagtgggc
    13441 cacaccggat ttggtcgtat gtacgcttgc gccacctaat tgttcctgtg taacgtcttc
    13501 gcctgtaact gtttttacaa ctttcggacc agtcaggaac atgtaacttg ttccgcgggt
    13561 catgatattg aagtctgtca gggcaggaga gtaaaccgca ccgccggcac atggaccgaa
    13621 gataccggaa atctgaggaa taaccccgga agccaagata ttacgttgga agatttctgc
    13681 ataaccggcc aaggcgttga caccttcctg gatacgtgcg ccacccgagt cgttcagacc
    13741 gataacggga gcacccatct tcatggcctg atccattact ttacagatct tcatggccaa
    13801 tgcttcggat aaagcaccgc cgaacacggt gaaatcctga gcataaatat ataccagacg
    13861 tccgtcgatc gttccgtaac ctgttacgat accgtcgccc aaatacttag ttttttcaat
    13921 accgaagttt gtacaacgat gttgtacgaa catatcgaat tcttcaaaac ttccctcatc
    13981 cagcaacatg gcaatacgtt cgcgtgcggt gtatttacct tttttgtgct gagattcgat
    14041 tcttttttct ccaccaccta aacgagctgt ttcgcgaagg gcgataagct cctttacttt
    14101 ttcaagttgg ttactcattg tactatagat ttgttgttag aaatgaactt atttaattgg
    14161 caattaacga ttgagaattg acaattgaat agcatcaaat aattgtcaat tctcaattgt
    14221 caattgtttc ttattttccc ggcatgcaaa gttcggtcag aacgctgcat gtcgatttcg
    14281 ggtgaaggaa tgcaatgttc aagccttctg cacctccacg aggagctttg tcgatcagct
    14341 tgataccttt tgattcggct tcgtccaatg ctgcctgtac gtcgggaaca gcaaatgcaa
    14401 tgtggtggat accttcacct ttcttttcga taaatttagc gattgtactg tcttcacttg
    14461 tcggctccag caactcgatc ttagtctggc ctactttaaa gaatgcagtt tttactttct
    14521 ggtctgctac ttcttcgatg ttgtagcatt ttagtcctaa aacttcttca taatacggca
    14581 ggcaagcttc gatgctcttt actgcgatac ccaaatgttc gatatgtgta agttccatgt
    14641 caataataat ttagtaattt aatattgctt tttgttctat gttggcaaag gtacactctt
    14701 tttattaata gagaaataat tcgttaatat ttatcagcat gatccggata tgtttaaaaa
    14761 gcatattttt gaaatcatgt ggttaaaaat caacgataag tcgaatattc aattgtcttc
    14821 cggtcaggta attagggatt gcgtactggt ggttgtctat attggtaatc caataatagg
    14881 aactagtgtt ctttatgtcg aacaagttga aaatatccaa tccgagccaa atgttcttga
    14941 gattgcggaa gaatccgcga tccatgattg catccgttcc cccggcaagc tggtaggaga
    15001 aaccgaggtc cacgcgtttg taggtcggag tacggaaata gccgtcctcg tagcctgtac
    15061 gtggggctgt gacgggaagg ccgccggaca gtacgccttt cagattcagt ttgacacgtt
    15121 tgtatccggg gaaataatcc tgaaaaaaga gcgagacatt ataaccttgg ctgttaggca
    15181 tcggtacata ttcgctccct cggatgcttt gctccgcttt cattagggag aagctgatcc
    15241 aggagtccgt acccggaaca aattcgccga agaatttgac atcgagcccc atcgcatggc
    15301 cttgcgcaca gttctcgccg tagtatcgga ttttgacatt atccaccgta taggggttca
    15361 ggttatccaa ttttttataa tacatatcgg cactgacttt gaaatttctg ccggatgccc
    15421 ggaatgtata atcgcctcct gcaatgacat ggatggaacg ctgtgatttc aggtttttgt
    15481 tcagttgtat gatactgttg ccgtgttcgt cctgcacagt tgtacgtaat tccttataga
    15541 acggagactg ataatacaga ccggaagcca gccgaaatgt caggttctgg tcgaagttcg
    15601 gaatgaaacc tattgaagca cgcgggctga atataaattc cctgttataa ctccaatagc
    15661 tgccgcgtac accaccaacc agcgtgaaca gtccttgttt ggtacgaaac ttgaatacat
    15721 cctgcaaata gccggaaata cgtgtgcttt ccagtttgtt atccgagaac aggtttgcga
    15781 tcacgttgac attcccgccc ccttgcggta acgagtatcc ggcggagtcg cgtttttccc
    15841 attcgctgat cttgtcgttg attttctcca actggacggt agcaccccat ttcaacgtat
    15901 tgttttttat gcgagcgaca ccataatgcc cgacattcat gatattggag tgcagacggt
    15961 tgcgagcgtg ctcgttatag cgtgcgatgg ataatttctg tatttctccg cctccttctt
    16021 cggctgcatc tcccagccag taatcaccgg caatatcata tccttcctct tccttactgg
    16081 taaaggcgga tgcttgcaag ccgagttccg tattgtcgtt caggttatgc tttaaagtga
    16141 gtgctccgaa taacgtttcg aacttatccc gttcctggcc actcatgaat actttaaatt
    16201 ttttggcatt tgttgccgtt ccaaaagaag tctctcgggt gtggggaatg aacttataat
    16261 tgtttatggc taagtttccg agaaagttga tctcccattt gggggcaagc tggtatgtca
    16321 tataagtctg caaatcaatg aaattaggat catattcggc atccgtatcg gttgttttca
    16381 aaagagatcg tcctgttttg taacggaaac cggtcacctg tgtgaacttg ccggaagaac
    16441 tgcccacata agcattggct cccagcaggc tggcggaagc cgaaccttcg aatcctttcg
    16501 gttttttgta ggtgatgtcc agcacggaac tcatcttgtc cccataacgg gcttcgaatc
    16561 ctccggcgga gaaattgacg gcttccgtca tgtccgggtt gataaaactc aacccttcct
    16621 gttgtccgga acggatgagc agcggacgga acacttccag tccgttcaca tatacgatgt
    16681 tttcgtcata gctgccgccg cgtacggagt attgcgaact taattcgtta ttggaagtaa
    16741 cgccagcaaa tgtaacgacc agactttcaa tgcttcctcc ggcagggtcg gggagtagtt
    16801 tgacgcggtc ggcattcagg gtttcaaggg tggttgtctg ctttcggatg gcggtagcta
    16861 cgacttctcc cagttcgagt gatgtatagt tcatctgcac gttgagacgc atatctttgg
    16921 ttacctgagg taggatcctt tcggccttgt tgtagcccag gcatgaatag ataagcgtca
    16981 ccgagtcacc ggtagcgacc gaaagcgagt agtggccttt ttcattactc atcgtcccgt
    17041 ttaacgtgtt cttgacccgg atattgacca agtccagcgg attaccgtcc gcgtcgcgga
    17101 tataaccgct gattttggca cgtccctgcc cgaaagcact tatcgaaaat aatataaata
    17161 gtagtgtagc tattgcacga atcttcatat tccatctaat tattaaatct acaaacgcgg
    17221 gaaacaacga tttattttca atgaaaggca atttctcact atctttgtgc cttatataaa
    17281 taattaagga aagaagatgc ctttaaacct acagaagaac ttgccagctg ttgagctgtt
    17341 gaagaaagag cacatctttg tgatggactc gttgcgtgcg tctgagcagg acattcgtcc
    17401 gctacgtgta gttgtgctga acttgatgcc actgaagatc acgacggaga cggaccttgt
    17461 tcgcctcctg agcaataccc ccttgcaagt ggagctcgac tttatgaaga taaaaggcca
    17521 tactcccaag aacacgccga tcgagcatat gaaggaattc tataaagact ttgacgagat
    17581 gcaggatgat ttttacgacg gcatgattat cacaggtgct ccggtagagc agatgccttt
    17641 cgaggaagtg aactattggg aggaagtgac cgagatattc gattgggcgc gtacgcatgt
    17701 gacttctacc ttatatatat gctgggcggc gcaagccggg ttgtaccatt tttatggtgt
    17761 ccccaaatat gatctgccag ccaagatgtt cggcgtgttc cgccatacgt tgcgcgagcc
    17821 ctatgtgccg atcttccgag gcttcgacga cgagttctat gtgccgcaca gccggcatac
    17881 ggagatacgc cgcgaggatg tgatgaaagt tcccgatttg acgctcttgt ccgaaagcga
    17941 agagtctggt gtctatatgg cgatggcgcg cggaggacgc gagtttttta tcaccgggca
    18001 ttccgaatac tcgccttaca cgctgaatga cgagtatatg cgcgacgtga acaagggatt
    18061 gccaattgcc gttccccgta actattaccg taataacaat ccggccctcg gtccggtggt
    18121 ccgctggcgt ggtcatgcca atcttctgtt caccaactgg ctgaactatt atgtctatca
    18181 ggaaaccccg ttccgtatcg aggatatcag caagttgggt gatttgtaat caagaaataa
    18241 gaaataatag catgcaaaca aaatcccgtc ctatagaact tctctctccg gctaaagacc
    18301 tcaattgcgg gattgaagcg attaatcacg gtgccgatgc cgtctatatc ggtgcaccca
    18361 agttcggtgc gcgtgctgct gccggcaact ctttggaaga tatacgcgag ctttgcgagt
    18421 atgcgcatct gtatggcgcc cgcatctatg ttacgcttaa cacgatattg aaagaagatg
    18481 agttggaaga agccgaacgg atgatctggg atctctggcg tgtcgggacg gatgccctga
    18541 tcattcagga tatggggatt acccggctga acctgcctcc tattccgctt cacgccagca
    18601 cgcagacgga caatcgtaca ccggaaaagg tccgtttcct cgaagccgca ggctttacac
    18661 aggtggttct ggcacgtgaa ttgtcgctga acgagattcg ccggatatcg gaagcgacta
    18721 ccgttccgct ggaagtattc gtgcacggcg ccctctgcgt cagctatagc gggcaatgtt
    18781 atctgagcgc cgctttgagt ggacgtagtg ccaatcgcgg agaatgcgcc caatattgcc
    18841 gcctgcccta tacgatggtc gatgcgacag ggacggagat cgtcacccat aaacacttgc
    18901 tttcgctcaa ggacatgaac cgctccgatc agctggaagc cctgttggat gcaggtgttt
    18961 cttccctcaa gatcgaaggg cggttgaaag atgtcggcta tgtcaagaat atcacggctt
    19021 attatcggaa gaagttagat gcagtcctgt cccgccgtcc ggaatatcgt cgtgcttctg
    19081 ctggtcgaag cacttatacg ttcgagccgg tagctgaaaa gagttttaac cgtgggttca
    19141 ccccgttcct tttggaggga cggacggcgg atattaccgc tttcaatacg cctaaatcgc
    19201 tgggtgaacc tgtcgggacg gtcaaagaga tcaaaggcaa ttcttttact gtggccggct
    19261 tgaagcagct gagcaacgga gacgggcttg ttttcttcaa taggaaaggc gaattggaag
    19321 gttttcgtgt aaaccgggtg gaggcaaacc gggtgtttcc gctggatatg ccgcagctta
    19381 cccccaagac tccgctttac cgcaatttcg accaggcatt tgataaactg ctcgccaagc
    19441 cttcagccga acgcaagctg tccgtggaga tcgagttctt ggacaatccc ttcggtttta
    19501 cgctttgtat ggaggatgag acgggagcac ggatcatgct gaccgagccg tttgcgaaag
    19561 agctggcgcg tcgtgaacgg caggataata tacggacaca gctatccaag ttggggaata
    19621 cgcctttcga ggcatcgaag gtggtggtcg gtttgtctga aaactggttc gttccctctt
    19681 ctctgcttgc cgatatgcgc cgtagaggag tggagaagtt gctggaagca cgccgtgccc
    19741 gctatcctcg tgagacagtg aaacgtgtgc agccgtccgt gtcgatacct ttccccgaac
    19801 gccaacttac ttatttgggg aatgttgcca acgggaaagc ccgttcgttc taccaggatc
    19861 acggggtgga acagattgac ccggcatttg aactgtctcc ccggaaagat gttccgttga
    19921 tgtttaccaa acactgcctg cgctacagca tggggtggtg tcctacttat caaaaagaca
    19981 agtctcccta caaggaaccg tattatctgc tttataaaga tacgcgcctc cggttgcagt
    20041 tcgactgcaa gcattgtcag atgttggtat ttgaaagttg aaaattatga gaacgctatt
    20101 gtcagaacgg ataagaatga ctgtccggtg aaagaagcca tgatccgttt gacaaaagta
    20161 ttccagcaat aaaggagccg ataggtatgt gataacagtt tcatggggat gaaaaagaag
    20221 tttcatccct atgaaaataa agtttccctt gcatgaaaat aaagttttct ttaaggggaa
    20281 cgggaaggta gtgcaaggtt atatagcctt tcctaataac tccatatatt ttgccacccc
    20341 tttcgtgtct tctggagccg gactccaggg agcgaaattt tccggagcga gcggagcgaa
    20401 cggcccttcc ttgatttcat atatgataga gccggattct agaactaaca gcccgtgcca
    20461 tgttcccgcc tttatttcgg cgccgtaaac accttctttc ggatcgagta tctgtgtttg
    20521 ggtgatttcc cctttgttgt caaagaggaa tacagcaatg cgaccgcgca gcaggaggaa
    20581 tatttcatct tttttagggt tcagatggcg gtgtgggcgg aggtaggttc ccggttccag
    20641 ggcattgagc aaacggttga cgggatcgtc caaatgctca tgaaagttgt agttcatgcg
    20701 tagccgaggc gactgtttgg cacgcccggt cgtttcattc aataaagctt cgtttatgat
    20761 cttcatgcga ataattgatt actggaggac gaatgtacaa aataaatatt ggctggtatg
    20821 ccatttctcc gtacatttgc agaaacctgt aaataaaaca gaatgaaacc tgctctaact
    20881 tattacgctc tgctggtctt acttctggca tcctgctttt cctgcaaaac agattcggag
    20941 aagaaaaagt ttgttatcgg cgtctcgcag tgtacgcttg aaggttcttg gcgtaaatcg
    21001 atgttgctgg atatgaaggt gcaggcctcc gaatatccgg gcgtctccct gttagtcgag
    21061 gatgcagcgg acagtagtct gttgcaggtg gagcagatac gcagcctgat aaaacgtaag
    21121 gtcgatctat tgattatctc cgccaatgaa tcggaacctg tcactcctat tgcgattgag
    21181 gcctaccgtg ccggcattcc gactatcctg gtagaccgga agatcagttc ggacgaatat
    21241 acgacttata tcggtggtaa caattacgag atcggtcgcc aggccggctt tttcgtgaac
    21301 cgacaggtga aagagaaata tcctaccgta ttggaagtat ggggcttgtc cggttcttct
    21361 ccggcgcagg atcgccatcg cggttttatg gaggttttga actcccgcat caaggtgaag
    21421 gaaatattcg ggaaatggaa gccggaaacg gtggagaagg agatagcgga aatggattcg
    21481 ctggaggagg tggatgttgt gtttgcccat aatgatgtga tggcaatggc tgcccgcagg
    21541 gcaatcgaaa ggatgcatcc cggattggcg gacaggatta gctttgtggg gatcgatgcc
    21601 gtttcgggac ggggatcggg gctggaagcc gtcatgcacg gagagttggc cgcttcggtc
    21661 ttgtatccga cgggtgggag ccttgctatc cgtgtggcca tgcagatatt gaacggagaa
    21721 gatgtgtccc ggcaatattt gctatcttct gccttgatcg ataagaacaa tgccggaacg
    21781 ctgtttatcc agtccgaaca ggtggtcgac tatcagcacc agatcgagtt gcaacgggag
    21841 aatttggaga gtatgctttc caaatacacg ttcctccaaa actccgtcgg cattatcctt
    21901 ttgctgatgg ggatgttgct tttgtccgcc ttgtacgtgg tccatgtgaa ccgggcggtg
    21961 aagcggaaga accgcgagct gaaacgtacg aacttgcagg tgcaacagca aaaagaagaa
    22021 ttggctgagg caaaccgtta tattgagaag tcgacggctc agaaactgca attctttacc
    22081 aatatcacac acgagatcaa gacgccgttg acgttgatcc tcggtccgct cggcaagctg
    22141 tcgaaagagg ctccggaagg ttcttcattg gcagacgata tccgtatcat tcggaaaaat
    22201 gcggaaagat tgaagagagt cgtggaccag ttacttgatt ttcgaaaggt agagagcaat
    22261 aagatgaata tgcgggtcgg agaggtagat ttagttgctt ttgtggcaga agtgaaatct
    22321 tatttcgata cgatggctgc caccaagcag atacatttca cgtttgagca tgactgccct
    22381 tctgttaata tatgggtaga cagggataag atggagaaga ttctggccaa tcttttgtcc
    22441 aacgcattca agttcacgct ggacggaggt acggtcacga tccatctgaa agataaagga
    22501 gatcaggtcg agctttctgt cgaagataat ggcaaaggta ttccgtcgga aaatattgct
    22561 tccgtctttg accgtttctt taccggtgac cagaactatg tgacgggaac ggggatcggc
    22621 ctgcacttga cgcgtgagtt cgtccacatg cacaaaggca cgatccgggt ggagagtgtt
    22681 ccgcataaga gtactgtctt tacggtcatc ctcttgaaag gtaaatctca ttttgacgaa
    22741 tcttgtacat tcgatctttc cgtaaccgag ctttccagtg gtgtcgccga cttgaacacg
    22801 gatgaattgc aggaggtttt gaaccgtacc tacaattata ctgttctggt cgtagaagat
    22861 gatcttgata tacagagtta cttgcaggcg gaattaaaac agaacttccg tgtgttggtt
    22921 gccgataacg gcgtgaaggc tttggaggtg ctgatgagcg aagaggtttc gatggttatc
    22981 agcgatgtga tgatgccgga aatgaacggt ttcgatcttt gtcgtaagat caagtcggat
    23041 attgtcctga gtcatcttcc ggttatgctg ttgactgctt tgtccgacga caagcaacag
    23101 atgtacgggg ctgccagtgg tgcggacgcg tatatccaga aaccttttaa catagaagtc
    23161 gtgaaactgc gtatcatcaa gctgctggag gaccgtgtcc ggttgcgtga ggcttatgct
    23221 cgcgatgctt cttcgcctgc tgtttccgtg aaggaggaaa aagcgggaag catggacgat
    23281 ctttttatga atcgtttctt gaaactgatc gaagagtcct atgccgatcc ggatttcagt
    23341 attgagaaag gtagtgaaaa attgggcttg tcgcgtgtgc atctttaccg gaaggtgaag
    23401 gagcttgccg gagtgacacc gaccgatttc ctgcgtaact atcgtttgaa gaaagctgct
    23461 gctctactcc gacggaaagc cgggaatgtg aatgaggtgg cttatgcgac gggcttcggt
    23521 tcgcctgctt atttctcgaa atgttttaaa gccgtttaca atattactcc gacggagtat
    23581 ctggaaaagg aataatattc ttctctttga taacgctcgt tacatttgtg taacacttgt
    23641 gcatgtaact cgaaaataag agtataatgt aacaagtgtt atcaatcttg tagcattagt
    23701 tatcgtcgca tctgctacct gtctctatct ttgcatcgta gataataaat tatccttgtc
    23761 aaataaacta taatgaaaca atgcaaagca acaataagaa accggtcgta gtaggcatag
    23821 gagaactcct gtgggacatg ttgccaacag gaaagaaagc aggtggtgct cctatcaatt
    23881 ttgtctacca tgcgtcgcgg ttgggggcgg aaggatatgc tatcagcgcc gtgggagacg
    23941 atgggctggg gcgcgaaatc ctcgaagaac tggataataa ttcgatccgg tatctgatcg
    24001 agaaagtccc ttatccgacc ggaacggtac aggttactct gcaggatggt gtccctgact
    24061 atattattaa tgaacgtgta gcttgggatc atctttctcc gacgtcaaat gcgattgatt
    24121 tggccgaacg ggcgggtgcc atttgcttcg gtacgttagg acagcgttcc gcacagtcga
    24181 gagagacgat acaagcgatt ctttcttttg ctccggacga tgcttatcgt tgttttgaca
    24241 tcaatttgcg tcagcattat tatacgaaag agttgatcga agagtcgctt tatctagcaa
    24301 atatgttgaa ggtgaatgat ggggagttgg tcgtcctgcg ggatatgttt catttggaag
    24361 gaacggacaa ggaggtggct cattggttta tagaacacta taatctccgc ttggtggttc
    24421 tgacggccgg aggagcttat agtacgatat ataccgctaa tgaagaatcg actttgcaaa
    24481 ccccggaagt gcaggtggcg gatacggttg gagcaggtga tgctttctcc ggagcactgg
    24541 tcatttcgtt gttgaaaggg gcttcgctaa gggaagcgca tgaatttgcc gtccgcacag
    24601 ctgcttatgt ctgtacgaaa gagggggcat ggccggca
//
