LOCUS       gnlProkkaGCIPKHDH_114   5553 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GCIPKHDH_114.
ACCESSION   gnlProkkaGCIPKHDH_114
VERSION     gnlProkkaGCIPKHDH_114
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:48:09
            Original ID  :: gnl|Prokka|GCIPKHDH_114
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5553
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..336)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg114_1"
                     /sec_met_domain="ketoacyl-synt (E-value: 2e-11, bitscore:
                     32.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="APE_KS1 (E-value: 1e-28, bitscore: 88.8,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGINEDFLEANEVGILYG
                     NDSSAAPV"
     protocluster    1..5553
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:336]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..336
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..5553
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5553
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             complement(363..1091)
                     /NRPS_PKS="Domain: PKS_KR (3-169). E-value: 2.3e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_ctg114_2_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     215.6; E-value: 1.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg114_2"
                     /sec_met_domain="adh_short (E-value: 1.1e-35, bitscore:
                     111.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQL
                     VQEKGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEE
                     WSKVLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAA
                     TKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTPEEVADLVGFLA
                     SPASSYITGEVISINGGLYT"
     aSDomain        complement(585..1082)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg114_2_PKS_KR.1"
                     /evalue="2.30E-16"
                     /label="ctg114_2_PKS_KR.1"
                     /locus_tag="ctg114_2"
                     /protein_end="169"
                     /protein_start="3"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQLVQE
                     KGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWSK
                     VLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       complement(1017..1079)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg114_2_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg114_2"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             complement(1093..2616)
                     /locus_tag="ctg114_3"
                     /transl_table=11
                     /translation="MIADKSINLDTLHKVLFDNEKLELSEECIRKVEESFDFLQSFSSD
                     KIIYGINTGFGPMAQYRIEDQSLIDLQYNIIRSHSTGAGKPLPELYVKAAMIARLYTFL
                     QGKSGVHLELVSLLCEFINRGIYPFIPEHGSVGASGDLVQLAHIALTLIGEGEVFYQGK
                     LCNAATVLQENGLKPFSMRIREGLSVTNGTSVMTGIGIVNLIYAKKLLRWSVAASVMMN
                     EIAASYDDFMAQALNEAKHHKGQQEIAAMMREWVAGSKCVLQRENELYNQVHKEKIFEH
                     KVQPYYSLRCVPQILGPIYDELENAEEVLINEINSACDNPIVDPDTQNIYHGGNFHGDY
                     ISFEMDKLKIAVTKLTMLCERQINYLFHDRINGILPPFVNLGVLGLNYGLQASQFTATS
                     TTAECQTLSNPMYVHSIPNNNDNQDIVSMGTNSALLAKTVIENSYQVMAIQFMGMAQAI
                     DYLKIQDRLSSKSRQVYEEIRSFFPVFTNDTPKYKEIEMMIDYLKKEDK"
     CDS             complement(2823..3254)
                     /locus_tag="ctg114_4"
                     /transl_table=11
                     /translation="MEEIVFHHTLPIQLRFNDVDKFGHVNNTVYFSFYDLGKTEYFGSV
                     CPGVDWEKIGIVVVHIEANFVKQIFASDHIAVQTAVSKIGTKSFHLVQQVIDTKTNEVK
                     CVCKSIMVTFDLERHESMPLTKEWIEAICKYEGRDLQKA"
     CDS             3341..3547
                     /locus_tag="ctg114_5"
                     /transl_table=11
                     /translation="MILFSETGEKLVNNRLNWSFGTFILTSDMWKQSEGWKGTFKYGLF
                     LTYYLVEYVHISVEFLHRIVLET"
     CDS             3690..5552
                     /locus_tag="ctg114_6"
                     /transl_table=11
                     /translation="MVIYPNNYSNFRTIMEVIMKNKWLLCILLMLFLPFGLFAQVAPPL
                     EKQKTETQEAPENNNEVTTNSDTNTDGDAGKTIKGVINDEQGETIIGASVIIKGEDTGT
                     TSDMDGRFTLEAPEGAILVISYIGYHTQEVKVRKRSLLRVVLKEDNQLLDEVVVVGYGT
                     VKKSDLTGAVSGVSNRQYKNQPVQRVENILQGRTPGVEVTATSGMPGASMKVRVRGTTS
                     INKSSDPLYVIDGIISSSGLDGINPSDIQSMEILKDASSTAIYGSRGSNGVILITTKQG
                     SEGKAQVTFDASIGLSTVRKQYDLLNAYEYATALNDIRGSSTISAEDLEAYKNGTKGIN
                     WTDLLTRTGITQDYRLAISGGNEKVKYLISGNVLDQEAITIMSDYKRYGIRANIDSEVK
                     PWLTISAKLNASSLHKHNEGGANWLHVTNFSPTMELKDPETGVYNTDPYNMIGSSPYGE
                     MIVNNSDSYSYNLNANLTLLFKIMKGLTLSVQGGYDYDNSPSYSFRSKLDSPGAINSAS
                     NTNALHNYWQNTNNLTWQKQFGDHSFTAMGVWEISRSWDSQLKGTGSNLNNESVGYWNL
                     GNAAIRDASNSYTEFSLASGIVRANYDYKKRYFITAALRADGSSK"
ORIGIN
        1 aacaggagcg gcactactat cattgccata caaaataccc acttcattgg cttcgagaaa
       61 atcctcatta ataccggcat tacggaaagc ttctaatgta gcgagataag catattctcc
      121 ctgctccggt agacagagac gtttacggcg gtccaacaac ttcttcaagt cgggacgttc
      181 caatatcccc gttaatgcag aaaagtaacc caattctttc cgtaccgggt ctatgccaat
      241 tcccgatttc ccattatata gtgagtcttt tacttcatcc agattcttgc cgatgcaaga
      301 gtaaatcccc attcccgtga taacaactct tttcattatt ttgtctattc tatgctttta
      361 ttttaagtat atagtcctcc gttgatggaa atcacttctc ctgtgatgta ggatgaggct
      421 ggagatgcca ggaaaccgac caggtcggca acctcttccg gagtgccgaa acgtcccgcg
      481 ggaatatgtt tcttccattc gttctcatca attccttccg tcatatccgt acggatgaat
      541 cccggagcta ctgcattgac tgttactttc ttcttggcaa cttcctgtgc cagtgctttg
      601 gtagcagcta ttacgccacc tttggctgcg gagtaattgg cttggccggg cattccctga
      661 atgcccgaca atgacacgat atttacgata cgtccataac gtttgaccag catattcttc
      721 aataaaggct gtgtcacgtt gaagaatccg ttcaggctga tatcgagcac tttgctccat
      781 tcttctcctg tcatccagag catcaggttg tctttgcgga tacctgcatt gtttatcagt
      841 acctcgatat attcgtcagg gtgttgggaa gcccagttgc ccaaagcaag ggtgatagcg
      901 gcagggtcgg tcacatcgaa cttcatcaac tcgccattac ttcctttttc ctgtactaac
      961 tgcaacgttt tctccgcttc tgcgtcatta ttctgataat ttatcagtat aaagtagccc
     1021 atttccgcca gtttacaact gacagcacgg ccgatacctc ggcttcctcc ggttactaat
     1081 gcatatttca ttttatttat cttctttttt gagatagtct atcatcattt ctatctcttt
     1141 atatttaggt gtgtcattgg taaatacagg gaagaaactg cgtatttctt cataaacctg
     1201 cctgcttttg gaacttaggc gatcctgtat tttcaggtag tcgatagctt gtgccattcc
     1261 cataaactgg atagccatca cctgataaga attctcaatg actgtttttg ctaatagagc
     1321 cgagttggtt cccatgctga caatatcctg attatcattg ttgttgggga tactgtgtac
     1381 atacatcgga tttgataatg tctgacattc cgctgtggtg gaggttgcag tgaattgtga
     1441 agcctgtaaa ccatagttca atccaagcac tcccaaattt acaaacggag gcaggatgcc
     1501 attgatacgg tcgtggaaca gatagttaat ctgtctttcg caaagcatag tcagcttggt
     1561 cacggcaatt ttcaacttgt ccatttcgaa agaaatgtaa tctccgtgga agttgccgcc
     1621 atgataaata ttttgtgtat ccggatcgac aatcggattg tcacaggcgg aatttatttc
     1681 gtttattaat acttcttccg cattctccag ttcatcgtaa ataggaccga gtatttgcgg
     1741 aacacatcgc aaggaataat agggctgtac tttgtgttcg aagattttct ctttatgcac
     1801 ctggttgtat agctcgttct ctctttgaag cacgcattta ctgcctgcca cccattctct
     1861 catcatagca gctatctctt gttgaccttt atgatgcttg gcctcgttta atgcctgtgc
     1921 cataaaatca tcataagagg cggcaatctc attcatcatt acagaggcag ccaccgacca
     1981 acggagtagt ttttttgcat aaatcagatt gacaataccg atacctgtca ttacagaagt
     2041 accgtttgta acggataaac cttcacgaat acgcatggaa aaaggtttca ggccgttttc
     2101 ctgaagcacc gtagctgcgt tacacaattt accctgataa aaaacttccc cttcccctat
     2161 taacgtcagg gcgatatggg ccagttgtac gagatcgccg ctggcaccta cacttccgtg
     2221 ttcgggtatg aacggataaa ttccgcggtt gataaattca cagaggagag aaaccagttc
     2281 cagatgcact cctgacttcc cttgtagaaa agtgtacaaa cgggcaatca tagctgcttt
     2341 tacataaagt tcgggaagcg gtttgccggc accggtggaa tggcttcgga tgatattata
     2401 ctgaaggtcg atcaatgact gatcttctat tctgtattgt gccattgggc cgaaccccgt
     2461 attgatacca taaataatct tatcgctgga aaaggattgc agaaaatcga agctttcctc
     2521 tacttttcga atacattctt cagagagttc cagcttctca ttatcaaaca atactttatg
     2581 aagggtatct aaatttatac ttttgtcagc tatcattttc tgtactagat attttatgcc
     2641 ttaataataa ggtgcaaaaa taggcaattt ctgttatata gcggacatga atcaggataa
     2701 aactttttct aaggaattgg ttttgcttgt tttgtttctt attcgtggga gatttgttcc
     2761 ccggtaccgc tcgatgcttt cattggtgcc ggagggtgtc ttcatcggtg gggggaatca
     2821 atctatgctt tttgcaaatc ccgtccttca tacttgcaga tcgcttctat ccattctttg
     2881 gtcagtggca tggactcatg tctttcaaga tcgaaagtaa ccatgatgga tttgcaaacg
     2941 catttcactt cattggtttt cgtgtcaatg acttgttgaa ccagatgaaa gcttttggta
     3001 cctatcttag agacagctgt ttgtacagcg atgtggtcgg atgcgaaaat ttgcttaacg
     3061 aaattcgctt caatatgaac aacgacaatg ccaatctttt cccaatctac tcccgggcat
     3121 actgaaccga agtattcagt ctttcccaag tcgtaaaagg agaagtaaac cgtgttgttg
     3181 acgtgaccaa atttgtctac atcattgaat cgcaattgga taggtaatgt gtgatgaaat
     3241 acgatttctt ccattgtttt ctcttaaacg ttttaaattc gacacaaaaa tagcactttt
     3301 gctttcttgc ttgaaattgg ggcaaagata gatatttctg atgattctgt tctcggagac
     3361 gggggagaaa ttagttaata atcgtttaaa ctggagtttt ggaacgttta ttctgacttc
     3421 tgatatgtgg aaacaatcag aaggatggaa aggaactttt aaatacggat tattcttaac
     3481 ttattatctt gtggaatatg tccacatttc tgtggaattt ttgcacagga tcgtgcttga
     3541 aacttaatct ggttattaat gctttttttc tttattgcaa attgtttatg tatttgaaaa
     3601 ttagtgatat aatctctttt gttaaacttg ataagtctcg ttgtatcagt cttttgttat
     3661 gcttttggca cataaattgc ccaatattga tggtaatcta tcctaataac tattctaatt
     3721 ttagaacaat aatggaagta ataatgaaaa acaaatggct attatgcatt cttttaatgc
     3781 tgtttctgcc tttcggatta ttcgcgcagg ttgctcctcc tcttgaaaaa cagaagacag
     3841 aaacacagga agccccggaa aataacaatg aagttacgac aaacagcgat actaataccg
     3901 acggggatgc tggaaagaca atcaaaggag tgattaacga cgaacaggga gagacaatca
     3961 ttggtgcttc cgtcattatc aaaggtgaag acaccggaac taccagtgat atggatggta
     4021 ggtttactct cgaagctccg gaaggagcga ttttagtgat ctcttacatc ggctatcata
     4081 cgcaggaagt gaaagtcaga aagagatctc ttcttcgtgt tgtgttgaaa gaagacaatc
     4141 agttattgga tgaagtggta gtggtaggat acggaaccgt caaaaagagt gaccttacgg
     4201 gtgctgtgtc cggtgtatcc aacagacaat acaaaaatca accagtacaa cgggttgaaa
     4261 atatactcca gggtcgtact cccggtgtag aagtcactgc tacgagtggt atgcccggag
     4321 caagtatgaa ggtgcgcgtt cgtggaacta cctctattaa taaaagcagt gatcctttat
     4381 atgtgattga cggtatcatc tcttccagtg gcttggacgg tattaaccct tctgatatcc
     4441 agtcgatgga aatattgaaa gacgcttcct ccactgccat ttacggttcc cgtggttcga
     4501 atggcgttat cctgataacc accaaacagg gtagtgaggg aaaagcacag gtaacattcg
     4561 atgcatcgat cgggctttcg actgtcagaa aacagtatga cctgctgaac gcctatgaat
     4621 atgcaactgc actgaatgat attcgcggat cgtccactat ctctgccgaa gaccttgagg
     4681 cttataaaaa tggaacgaaa ggaatcaact ggactgatct tctgactcgt acaggtatca
     4741 ctcaggatta tcggcttgcc atatccggag gaaatgaaaa agtgaaatac cttatttcgg
     4801 gaaatgtgct tgatcaggaa gccatcacga tcatgtccga ttataaacgc tatggaattc
     4861 gggcaaacat cgactcggaa gtgaaaccct ggttgacaat ctctgcaaaa ttaaacgcat
     4921 ccagtcttca caaacacaat gaaggtgggg cgaactggtt gcatgtcact aacttttcgc
     4981 ctaccatgga gctgaaagat cccgaaaccg gcgtgtacaa tacagacccg tataatatga
     5041 tcggttccag cccttacggt gaaatgatag tgaacaatag cgatagctat agctataatt
     5101 taaacgccaa cctgacattg ctgtttaaga tcatgaaagg actgacgctt tccgttcagg
     5161 gaggttatga ctacgataat agtccttctt attctttccg gtcgaaactg gattcaccgg
     5221 gtgctatcaa tagcgcaagc aataccaacg cattgcataa ctattggcag aatactaaca
     5281 atctgacctg gcaaaagcaa ttcggagatc atagcttcac tgccatgggt gtatgggaaa
     5341 taagtcgttc gtgggactca caactaaagg gaaccggttc caatctgaac aatgaaagtg
     5401 ttgggtactg gaatcttggc aatgctgcta tcagagatgc gagcaattca tatacggaat
     5461 tttctttggc ttccggcatc gtgcgtgcta attacgatta taagaaacga tattttatta
     5521 ctgctgcatt aagagctgac ggttcttcta aat
//
