LOCUS       c00001_gnlPro..        11117 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BECNEDJF_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:39:19
            Original ID  :: gnl|Prokka|BECNEDJF_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11117
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11117
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3655:9686]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3656..9686
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11117
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11117
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..952)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="LTILARVNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFI
                     QSELNRRKPGQSKITTPRKEDDEVQFLSGIYEGKTTGTPIGFIIWNKNQHSADYDNMKN
                     VYRPSHADYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLVLRQKGIRIQAFTSQV
                     GNIKLNGSYTDYDLDKAEDTAVRCPDPATAEKMEALIAEVKSKGDTIGGVITCVAQGVP
                     IGLGEPVFGKLHAALGHAMLTINAVKGFEYGDGFEAALYRGSERNDRFFNDNGHINTHT
                     NHSGGIQGGISNGQDIYFRVAFKSVATILMEQETVN"
     CDS             complement(964..1542)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MKITANKFVAVTYDLNVGEGEERELMERATAETPLKFIFGTGAML
                     PAFEDALKGLEVGDKFNFSITPADAYGEYVEEHVLDLPKNIFEVDGKFDSEMIKEGNTV
                     PMMDSNGNRMNGSVLEVKEDVVVMDFNHPLAGETLHFNGEVIDVHEPTAEEIAALTAPA
                     GGCGCGCDDCGSGCGDHNHEGGCGCGGCH"
     CDS             complement(1640..2890)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.4e-42, bitscore:
                     133.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESKQFLNIIRIFDPDQQTELIEIMKQYNFDEIIERRGTNCVKY
                     DLLKKDFGNENLVPLWVADMDFRTPDFIVNAIKKRLEHEIFGYTFDSDSYYNSIIEWVH
                     YKHNWKIQREWLSYIPGIVKGIGFVLQCFTKPGDKVIIQPPVYHPFRIVPENMHREVVY
                     NPLKTVDDIYEMDFENLESVIDEHCKVLILCNPHNPGGVVWKKDTLVKLAEVCAKHNIL
                     VISDEIHAEMAYPQYTHHPFATVSETAANCSITFMAPSKTFNIAGIVTSYSIIPNAEIR
                     EKFYSFMEAGEFNAGTVFAYTATEAAYTYGAEWLQQMRMYITENVRFVDEYCKSKLPKI
                     KVYPPQASFLVWLDCRDLKLSQPELVSLFQDKAGLLLNDGSMFGPGGEGHMRLNIGCPR
                     SVLSSALDALKKAIDKK"
     CDS             3393..3500
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MNYCSTFAASNNNKDVRKDDEQCIAYYSRGGPSSH"
     CDS             3656..5491
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="ILVD_EDD (E-value: 3.5e-217, bitscore:
                     711.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSYSTEGRRMAGARALWRANGLKEEQFGKPIIAIVNSFT
                     QFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGELDNRHLDLID
                     AMIESADTSVSDERIAQVERNACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     VGRTQLFRDAARQIVENAYKYYRDGDESVLPRSIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAIAQEAEADFTMDDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGIMGIMNELLKSG
                     LVDGNVKRVDGMTLAEAVDKFAITSPNMTDEAVKKYKSAPAHRFSIRMGSQETYYKELD
                     TDRAAGCIRDIEHAYSKDGGLAVLKGNIALDGCVVKTAGVDESIWKFAGPAKVFDSQDA
                     ASEGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEIDIPERTINVKVSDEELAERRKAEEARGTK
                     AFTPPHRQRVVSKALRAYGKMVSSADKGGVRVVED"
     CDS             5515..7215
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-51, bitscore:
                     163.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKSLIAEGVDTIFGYPGGQAIPIYDSLYDYRDK
                     LKHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGFVDYEYKKVDYIRSYQPEPDINQDRIKAAAALINKAEKPFCLVGQGVLLGG
                     AEEELKAFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKVIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDAQEEYEKVIEKELYPMNGSLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKRTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLDVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRTVE
                     KREELDEAIAEMLNHNGAFVLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             7228..7779
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="ALS_ss_C (E-value: 5.9e-18, bitscore:
                     54.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENTVGLLNQITIIFTRRQLNIETLSVSPSAIQ
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVFQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNETCVVLEKSGHYDETQALFRELSETIGVLQFIRSGRVAITKS
                     RVERLSDMLAEMERKLQEKK"
     CDS             7787..8557
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="VVCELPQQKRIMDKDKSKIGEFHFVTEPYLLDFRGRVTIPMIGNY
                     LIHVASSHAAERGFGFNDMSERHTAWVLSRLAIEMIEYPAMSEPITLYTWVDEVGRLFT
                     SRCFELVDGNGKTFGYARSIWAAIDVETRRPTLLDIARLSAYVTDRPCPIEKPGKIAAV
                     ENETEGVPYFIKYSDLDINGHLNSIKYMEHLLDLFDLDLFKTKDIKRFEIAYQSEGKYG
                     MKLMLYKREADNGKYDMAICNEGKAICRAAVMWH"
     CDS             8643..9686
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_9"
                     /sec_met_domain="IlvN (E-value: 5.5e-45, bitscore: 142.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDEVIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYDKAVADGWVPGETLFGIEEACERATIIQVLLSDAAQIE
                     CWPRIKKYLTPGKALYFSHGFAITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQGR
                     GLNSSYAIFQDATGRAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQGL
                     LLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWMG
                     PFHDAVKPVFEKLYREVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVVR
                     KLRPENN"
     CDS             9848..11017
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MKKFQILVMLLWLSVCLAGAVESKIRLVHGPYLQNLGPDEVTIVW
                     LSDKPSVGWVELAPDDDTNFYATERPKYYDARNGVKNTSTIHTVKIKGLKPGTNYRYRV
                     FVQEVLSHVGHKIIYGNYASTDVYSKKPLVFKTSDPADNSVSFAMVNDIHGKNDLLTNL
                     VSKCDLKKTDFFLFNGDMVSVFNEENHIFDGFMDTATKLFASEIPMYYTRGNHETRGAF
                     ATEFQRYFSAKEENIYYTFRQGPICFVILDTGEDKPDSDIEYAGITVYDEYRTEQAEWL
                     RRVLDSKEYKDAPFKIIVAHIPPIGGWHGNLEVEQKFMPLLRDAKPDVMLCGHLHRFIH
                     QDATDRTPFPIIVNSNTAILKAAADPKELKIQVVDVDGKVVDQFSIKKP"
ORIGIN
        1 tattgacggt ttcctgttcc atcaggatgg tggcgaccga tttgaaggca acacggaaat
       61 aaatatcctg cccgttcgag atacctccct gtatgccacc ggaatgattc gtatgggtgt
      121 tgatgtgtcc gttgtcgttg aagaaacggt cgttccgttc cgagccacga tataaggccg
      181 cttcgaaacc gtcaccgtat tcgaaccctt ttacggcatt gattgtcaac atcgcatgtc
      241 ccaatgccgc atgcaacttt ccgaataccg gttcgcccag accaatggga actccctgtg
      301 ctacgcaggt gattacgccg ccgatcgtat ctcctttgga tttcacttcg gcgatcaaag
      361 cctccatttt ttcggcggtc gccgggtccg gacaacgtac ggccgtatct tccgccttgt
      421 ccaagtcgta atccgtgtat gagccgttaa gtttgatgtt cccgacctgt gaggtaaatg
      481 cttgtatccg gatacctttc tggcgaagaa ccagtttggc aattgctccg gctacgcaac
      541 gggcgatcgt ttcacgtgca gacgaacgtc cacctccgcg cgggtcgcgg attccgtatt
      601 tggtctggta ggtgtaatct gcatgggaag gacgataaac attcttcata ttatcgtagt
      661 ccgccgagtg ctggttcttg ttccagatga tgaaaccgat cggagtccct gtcgtttttc
      721 cttcgtaaat accggaaagg aactgtactt cgtcgtcttc cttgcgtggg gttgtgattt
      781 tggactgtcc cggtttacgg cggttcagtt cactttggat aaatgccgta tctagttcga
      841 taccggcagg gcatccgtct attacgcctc cgattccggg accgtgcgac tctccgaaag
      901 aggtcagtct gtatatgttt ccaaatgtat tcacccttgc taaaattgtc aattgtcaat
      961 tctttaatgg catccgccac atccgcatcc accttcgtgg ttatggtcgc cacaaccgct
     1021 tccgcagtcg tcacatccac aaccgcatcc accagcggga gctgtgaggg ctgcgatttc
     1081 ttcagctgtc ggttcgtgta catcaataac ttcaccattg aaatgcaatg tttcgccagc
     1141 caacggatgg ttgaagtcca taacgacaac atcttctttt acttccaaga cagaaccgtt
     1201 catgcggttg ccgttcgaat ccatcatcgg taccgtgttg ccttctttga tcatttccga
     1261 gtcgaacttg ccgtctacct cgaaaatatt ctttggaaga tccagtacgt gttcctccac
     1321 atattcgccg tatgcatcag ccggagttat agaaaaatta aatttgtcgc ctacttccag
     1381 tcctttcaga gcgtcttcaa aagcggggag catagcgcct gtaccaaaga tgaatttcag
     1441 aggtgtttca gctgttgctc tttccatcaa ttcgcgttct tcgccttcgc ctacattcag
     1501 atcgtaagta actgcaacga acttatttgc tgtaattttc atttgtaatt gtatttatga
     1561 taaataaaat ggcaacaaat ttacgcataa tttccgactt gtctgcccaa tctctggata
     1621 attaaatagg caaacggctt tatttcttat ctatcgcttt tttcaaagca tccagtgcgg
     1681 aagacaggac ggaacgcgga cagccgatat tcaaacgcat atgcccttca cctccgggac
     1741 cgaacatgct tccgtcgttc agcaacaggc cggctttatc ttggaacaag cttaccagtt
     1801 caggctggct tagtttcagg tcacggcaat ccaaccatac aaggaaagat gcctgagggg
     1861 gatagacttt gatcttcggg agtttggatt tgcaatattc atctacgaag cggacattct
     1921 cagtgatata catccgcatc tgttgcaacc attcggctcc gtatgtataa gccgcttctg
     1981 ttgccgtata ggcaaagacc gtcccggcat tgaattctcc tgcttccatg aaggaataga
     2041 acttttctcg tatttccgca ttgggaatga tcgagtagga ggtgacgatt ccggcaatgt
     2101 tgaaagtctt gctcggagcc atgaaagtaa tgctgcaatt ggcggctgtc tccgaaaccg
     2161 ttgcaaacgg atgatgcgta tattgcggat aagccatctc tgcatgtatt tcatcggaga
     2221 taacgagtat attgtgtttg gcacaaacct cggccaactt gaccagtgtg tcttttttcc
     2281 agacgacacc gcctggatta tgagggttgc aaaggatcag gactttgcaa tgctcatcga
     2341 tgaccgattc aagattctcg aaatccatct cgtaaatgtc gtctactgtt ttgagcgggt
     2401 tgtagacaac ctcacggtgc atgttttccg gaacgatgcg gaagggatgg tagaccggtg
     2461 gctggataat tactttgtca ccaggtttgg tgaagcattg caaaacgaaa ccgattccct
     2521 ttacgatgcc gggaatataa ctaagccatt cgcgttggat tttccagtta tgtttataat
     2581 gtacccactc gatgatactg ttataatagg aatccgaatc gaatgtgtac ccgaaaatct
     2641 catgctccag acgcttcttg attgcgttga caataaagtc tggtgtccgg aaatccatgt
     2701 cggctaccca aagtggaaca aggttctcgt taccgaagtc tttctttaga agatcgtact
     2761 tgacacaatt ggttccacga cgttcgatga tctcgtcaaa gttgtattgt ttcattatct
     2821 ctataagttc agtctgttga tcggggtcaa agatacgaat tatatttaga aactgtttcg
     2881 attccgacat ttgggtagtt acacaaccgg acttttaatt ttgtctcgtc ctgaaataga
     2941 ttgactgtgt attaaaaatc ctgttatagg ttgtctataa atgtaaataa ctgacacttg
     3001 taaatgagtc gggtacgaaa agtatcatag agtggcaact gccatacttt tatcgtcagg
     3061 ctataaagcc atagagcttt tgacctacgt cgaatatctt tttgcccaag gtcgaaaagg
     3121 cttttgccat taggcaaaaa ggctttcggc cttgggcaaa aacgtaagag gttataatta
     3181 aatctgtacg agacagggtg aaagcagatc tttaaggtga agcctactcg tatattcttt
     3241 catatgaaaa gttaggcgga aacaatccag acaggtattt cggatttgat aatggaagat
     3301 tggaaggatg tgttaaactg caagcctatc ttgtttcttt gcttgagaaa tgtaagataa
     3361 attgatattt ttcttttaat ttctttggtg gtatgaatta ttgttctaca tttgcagcat
     3421 caaacaataa taaagatgta agaaaagatg atgaacaatg tattgcatat tattctcgtg
     3481 gtggtccttc tagtcattag caggtaagga gaaaggtgtg caagaaattg tgaagtcata
     3541 taaagatatt tcttaagcct ttctccatac agagaagggc ttttttaata taataatatt
     3601 taggataaga aaataggggc ggttcgtgag ccgttcgaaa acaacaaata atatgatgaa
     3661 gaatccgtta agaagttcat acagcacaga gggcagacgc atggctgggg ctcgcgcttt
     3721 gtggcgtgcc aacggtctga aagaagagca gttcggtaaa ccgattatag ccattgtgaa
     3781 ttcatttacc cagtttgtac ccggccatgt ccatctgcac gagatcgggc agcaggtaaa
     3841 agcggagatt gaaaagttgg gttgctttgc tgccgaattc aatacgattg ctattgacga
     3901 tggtatcgct atgggacacg acggaatgct ctattcgctt ccttcgcgtg atattattgc
     3961 ggacagcgtc gagtatatgg tgaatgccca caaagccgat gcaatggttt gcattagcaa
     4021 ttgcgacaag atcactccgg ggatgctaat ggcatccatg cggctcaata ttccgactat
     4081 ctttgtctcc ggcggtccga tggaagccgg tgagctggat aaccgccatc tggatttgat
     4141 cgatgccatg atcgaatcgg ccgacacttc ggtcagcgat gaacggatcg cacaggtgga
     4201 acggaatgcc tgtccgggat gcggttgttg ttccggtatg tttacggcca actcgatgaa
     4261 ctgtctgaac gaagcgatcg gtttggcact tccgggcaac gggacgatcg tcgctacgca
     4321 tgtgggccgt acgcaactgt tccgcgatgc tgcccggcag attgtagaaa atgcctataa
     4381 atactatcgt gacggtgatg agtctgttct tccccgcagt atcgccaccc gtcaggcttt
     4441 cctgaatgcc atgtcattgg atattgcaat gggtggttcc accaatacgg ttctccactt
     4501 gctcgccatc gcgcaggaag ctgaggcgga cttcacgatg gacgatatcg atatgctctc
     4561 ccgcaagact ccttgcctct gcaaggttgc tcccaacacg cacacctacc acgtccagga
     4621 tgtgaaccgt gccggtggta tcatgggaat catgaacgag ctgctgaaaa gcggcttggt
     4681 agacgggaat gtgaagcgtg tggacggaat gacgcttgcc gaagccgtgg ataaatttgc
     4741 tatcacctcg ccgaatatga cggacgaggc tgtcaagaaa tacaagagtg ctcccgccca
     4801 tcgtttcagc attcggatgg gatcgcagga aacctattat aaggaactgg ataccgatcg
     4861 tgccgccgga tgtatccgtg atatcgagca tgcttattcc aaagatggcg gcctggctgt
     4921 cctgaaagga aatatcgcgc tggacggttg tgtggtcaag acggccggtg tggatgaaag
     4981 catctggaag tttgccggtc cggcgaaagt gttcgattcg caggatgcgg ctagcgaagg
     5041 catcctcggt ggaaaagtcg tctcgggcga tgtggtggtg atcacacacg aaggaccgaa
     5101 gggtggtccg ggtatgcagg aaatgcttta tcctacttct tatataaaaa gccgtcattt
     5161 aggcaaggag tgcgcgctga tcacagacgg tcgtttcagt ggcggtactt ccggtctttc
     5221 tatcggtcat atttctcccg aagctgcggc aggaggagcg attggactgg tgaaagacgg
     5281 cgatataatc gagattgata tccctgaacg tacgattaat gtgaaggtaa gcgatgaaga
     5341 gttggcagaa cgccgtaaag cggaagaagc ccgcggcaca aaagccttta cgccgcctca
     5401 tcgccagcgt gtcgtctcaa aagccttgag agcttacggt aagatggtca gttcggccga
     5461 taagggtgga gtgagagtag tagaagatta aacacaagac taaaataaag agatatggag
     5521 aaacagaaga taaccggttc ggaagctttg ctgaagtcac tgatagctga aggagtagat
     5581 acgattttcg gttatcccgg cgggcaagcg attcctattt acgatagttt gtacgattac
     5641 agggataaat tgaagcatgt attggtgcgt catgaacaag gggcgacgca tgctgcacaa
     5701 gggtatgccc gtgtatccgg taaagtaggg gtgacgttgg ttacttcagg acccggcgca
     5761 acaaatacca tcaccggcat tgccgatgca ctgatggaca gcactcctat ggtggtcata
     5821 gccggacagg tcccttctcc attgcttgga acagatgctt tccaggaagt cgatgtgatc
     5881 ggcattacgc aaccgatcac caaatgggcg taccagattc gcaagccgga agagatagcg
     5941 tgggctgttt cacgtgcttt ttatatcgct tctaccggac ggccggggcc tgttgtactc
     6001 gatttggcaa aggatgctca ggttggattt gtggattatg aatataagaa agtagactat
     6061 atccgcagct atcagccgga accggatatc aaccaggatc ggattaaagc ggctgccgcg
     6121 ttgatcaata aagcggagaa accgttctgc ctggtcggac agggggtttt gttgggaggt
     6181 gctgaagagg agctgaaagc attcctgctg aagaatgaca ttcctgccgg ttcgactgtt
     6241 ctcggtctat cggcgttgcc ttccgatttt cctttgaata agggtatgtt gggtatgcac
     6301 ggcaatgtcg gtccgaatag gaagaccaat gaatgtgacg tgttgatcgc catcggtatg
     6361 cgtttcgacg atcgtgttac tggcgatttg aagacatacg ccaagcaggc gaaagtgatc
     6421 catttggata tcgacaactc ggagatcggg aagaatgtac cggtcgatgt gaaggttctc
     6481 ggaaatgcca aacataccat tccgatgata actgcgttgt tggaagaacg gaaacgtccg
     6541 gagtggaatg ctgagtttga gcctgatgca caggaagagt atgaaaaggt gatcgagaag
     6601 gagttgtatc cgatgaacgg atctttgaaa atgggtgaag tcgttcgaaa agtgtccgag
     6661 gcgactggaa acgatgctgt tttagttacg gatgtcggac agaaccagat gatgggtgtc
     6721 cgctatttca aatataaacg cactcgtagc gtggttactt caggtggtct ggggacgatg
     6781 ggctttggcc ttcccgctgc tatgggagcc aagttcggtg cacctgaccg tacggtctgc
     6841 ttctttaccg gtgacggtgg gatgcagatg acgattcagg agttgggaac cattatgcag
     6901 gaaaaactgg atgtgaaaat cattatcctc aataataatt tcttaggaat ggtacgtcag
     6961 tggcaggagt tgttcttcca cgaacgttat tcgaatacga tcatggagaa cccggatttc
     7021 gtggcgatcg cgaaagcgta cggtattgct ggccgcaccg ttgaaaaacg ggaggaactg
     7081 gatgaggcta ttgccgagat gttgaaccat aacggagcgt ttgtgttggt cgccaatgtg
     7141 gaaacgtgtg gtatggtata tccgatggtg cctgccggag gaagcgtaac gaacatgata
     7201 ttaggagata agtaaggagg tgaagctatg acaacaaaaa aattatatac cgttattatc
     7261 ttttcagaga atacagtagg tcttctgaac cagattacga ttatctttac acgtcggcag
     7321 ttgaacatcg agacgctttc cgtttcacct tccgccatac agggtataca taaatttacg
     7381 atcacgacat ttgctgatga agatatgatc gacaaggttg tgaagcagat cgacaaacgg
     7441 gtggatatct tgaaggctta ctataatacg gatgaagatc tggttttcca ggagatcgcc
     7501 ctttataagc tgagcaccga gctgtttatc aagatgggga cggtcgagga tctgattcgc
     7561 aaatataacg cccgtattct ggaaatgaac gaaacgtgtg tcgttctcga aaagagtggt
     7621 cattacgatg agacgcaagc ccttttcagg gagttgagcg aaacgatcgg tgtcttgcag
     7681 ttcatccgtt ccggtcgcgt tgcgatcaca aaaagccgtg tcgagcgttt aagcgatatg
     7741 ttggccgaaa tggaacgtaa gttgcaggaa aaaaaataac gtacgggtgg tttgcgaact
     7801 gccccaacag aaaagaatca tggataaaga taaaagcaaa ataggggaat ttcatttcgt
     7861 cacggaaccg tacctgttgg attttcgtgg acgtgtaacg ataccgatga tcggaaacta
     7921 tctgatacat gtcgcatcca gccatgctgc tgaacgcgga ttcggtttca acgatatgtc
     7981 agaacggcat acggcttggg ttctttcccg tctggcgatc gaaatgatcg aatatccagc
     8041 catgtccgaa cctataactc tttatacctg ggtggatgaa gtcggccgtc tctttaccag
     8101 ccgttgtttc gagctggtgg atggcaacgg taagacattc ggttacgccc gttctatttg
     8161 ggcggctatc gatgtggaaa cacgccggcc gaccttgttg gatatcgcca ggttgagcgc
     8221 ttatgtcacg gatcgcccct gcccgataga aaagccggga aagattgcgg ctgtggagaa
     8281 tgagacggaa ggggttcctt atttcattaa gtacagcgac cttgatatca acggccacct
     8341 gaacagtatc aagtatatgg aacatcttct agacctgttt gatctagacc tgttcaagac
     8401 aaaagatatc aaacgtttcg aaatcgccta ccagtctgaa ggcaaatatg ggatgaaact
     8461 catgttgtac aagagggagg ctgataacgg aaaatatgat atggcgatct gtaatgaagg
     8521 caaagcgatt tgccgtgctg ctgttatgtg gcattgaaca aacatggtat gggcggatgg
     8581 tttgcgaact gtcctgacaa aagaattatt ttattaacac attacattta atagtagaaa
     8641 aaatggcagt aatgaatttt ggcggtgttg acgaaaacgt agtaacccgc gaagaatttc
     8701 cgttggaaaa ggcaagagaa gtattgaaag atgaagtgat tgcagttatc ggttacggtg
     8761 ttcaaggtcc tggacagagc ttgaacttgc gtgataatgg tttcaacgtt atcgtaggac
     8821 agcgccctgg taaaacctat gacaaagctg ttgccgacgg ctgggtaccg ggtgaaacac
     8881 tgttcggtat tgaagaagct tgcgaaagag caactatcat acaggtgttg ctttccgacg
     8941 ccgctcagat cgaatgctgg ccgcgtatca aaaaatatct gactccggga aaagcgctgt
     9001 atttctctca tggttttgct atcacttaca aggaacgtac caatattatc cctcctgctg
     9061 atgttgacgt gattctagtc gcaccgaaag gttctggtac ttctttgcgt cgtatgttcc
     9121 tgcagggacg tggcttgaat tcaagctatg caattttcca ggatgcaacc ggtagagcat
     9181 gggatcgtgt gatcgctttg ggtatcggcg ttggttcagg ctatctgttc gaaacgacat
     9241 tcaagaagga agtttattcc gatctgactg gtgaacgtgg aactttgatg ggggctatcc
     9301 aaggtttatt gttggctcaa tacgaaacat tgcgtgaaaa cggccacgaa ccttccgaag
     9361 cattcaacga aacagtcgaa gagctgactc agtctttgat gccgttgttt gctgaaaacg
     9421 gaatggactg gatgtatgca aactgttcga ctactgcaca gcgtggcgct ttagactgga
     9481 tggggccgtt ccacgatgcc gttaagcctg tatttgaaaa attataccgg gaggtcgcct
     9541 gcggtaacga agcgcagcgt tctatcgata cgaacagtaa gccggattat cgtgaaggtt
     9601 tggaaaaaga actggcagca ttgcgcgaaa gcgaaatgtg gcgtgcaggt gcagtcgttc
     9661 gtaaattgcg cccggaaaac aattgataga catcgcattt tttatttgag tgcataaaga
     9721 aagtggcaat tcggtatgaa ttgtcacttt ttttaatgaa aatgtatcat tttgataaga
     9781 aatctttgga tagtaatcga tatcttcgta gctataaatt cgaatttaat tacttaaata
     9841 ttatatcatg aagaaattcc aaattttagt aatgttattg tggctgtctg tttgtctagc
     9901 aggagcagta gagtcgaaga ttcggttggt gcatggtcct tatttgcaga atctagggcc
     9961 tgatgaggtg acgatcgtgt ggttgtcgga taaaccttct gtcggttggg tggagctggc
    10021 gccggatgac gatacgaact tttatgctac cgaacgtccc aaatattatg atgcccgtaa
    10081 cggagtaaaa aatacatcta cgatccatac cgtgaagatc aaagggctta aaccgggtac
    10141 gaactaccgt tatcgtgtct tcgtacagga agtactgagc catgtcggac ataagatcat
    10201 ctatgggaac tatgcctcga ctgatgttta ctccaaaaag ccgttggtgt tcaagacgag
    10261 cgatcctgcg gataattccg tctcatttgc gatggtgaac gatatacatg gcaaaaatga
    10321 cctgttgacg aacctagttt ccaagtgtga tttgaaaaag acggactttt ttctttttaa
    10381 cggtgatatg gtgtcagtct tcaatgagga aaatcatatc ttcgacggtt ttatggatac
    10441 ggcgaccaag ctgtttgcct ctgaaattcc gatgtattat acaagaggca accacgaaac
    10501 acgtggcgct tttgcaaccg agtttcaacg ctacttctct gcaaaagaag agaatatcta
    10561 ctatacattc cggcaaggtc cgatctgttt tgtcattttg gatacgggag aggacaagcc
    10621 ggattccgat attgaatatg ccggtataac agtctacgac gaataccgga cagaacaggc
    10681 cgaatggttg cgccgggtat tggatagcaa agaatataag gacgcgccgt ttaaaattat
    10741 tgtagcccat atcccaccga tcggcggatg gcatggaaac ttggaagtgg agcagaagtt
    10801 catgcctttg ctacgcgatg ccaagccgga cgttatgttg tgtggtcacc tccaccgttt
    10861 catccatcag gatgcaacgg atcgtacacc gttcccgatt atcgtcaatt ccaatacagc
    10921 tattttgaaa gcggctgccg atccgaaaga actaaaaata caggtcgtag atgtggacgg
    10981 gaaagtggtg gatcaattct ccataaagaa gccttgaaaa atgataagta gattgttggt
    11041 tatgaattga agaatttaga tgtatttgtc ttttatttta taagaaaata gtgataaaaa
    11101 ctttaaatta tatttgg
//
