LOCUS       gnlProkkaAGCLPCHE_252   1443 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGCLPCHE_252.
ACCESSION   gnlProkkaAGCLPCHE_252
VERSION     gnlProkkaAGCLPCHE_252
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:14:16
            Original ID  :: gnl|Prokka|AGCLPCHE_252
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1443
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..738
                     /NRPS_PKS="Domain: PKS_KR (6-172). E-value: 2.4e-16. Score:
                     52.0. Matches aSDomain: nrpspksdomains_ctg252_1_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     215.5; E-value: 1.3e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg252_1"
                     /sec_met_domain="adh_short (E-value: 3.9e-36, bitscore:
                     111.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKMKYALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKT
                     LQLVQEKGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMT
                     GEEWSKVLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGV
                     IAATKALAQEVAKKKVTVNAVAPGFIRTDMTEGIDENEWKKHIPAGRFGTPEEVADLVG
                     FLASPASSYITGEVISINGGLYT"
     protocluster    1..1443
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[764:1442]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      765..1442
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..1443
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1443
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     aSDomain        19..516
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg252_1_PKS_KR.1"
                     /evalue="2.40E-16"
                     /label="ctg252_1_PKS_KR.1"
                     /locus_tag="ctg252_1"
                     /protein_end="172"
                     /protein_start="6"
                     /score="52.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGSRGIGRAVSCKLAEMGYFILINYQNNDAEAEKTLQLVQE
                     KGSNGELMKFDVTDPAAITLALGNWASQHPDEYIEVLINNAGIRKDNLMLWMTGEEWSK
                     VLDISLNGFFNVTQPLLKNMLVKRYGRIVNIVSLSGIQGMPGQANYSAAKGGVIAATKA
                     LAQ"
     CDS_motif       22..84
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg252_1_0001"
                     /evalue="3.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg252_1"
                     /protein_end="28"
                     /protein_start="7"
                     /score="13.5"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVSCKLAEMG"
     CDS             765..1442
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (64-226). E-value:
                     4.3e-14. Score: 44.1. Matches aSDomain:
                     nrpspksdomains_ctg252_2_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 104.2; E-value:
                     1.3e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg252_2"
                     /sec_met_domain="APE_KS1 (E-value: 3.6e-78, bitscore:
                     250.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVITGMGIYSCIGKNLDEVKDSLYNGKSGIGIDPVRKELGYF
                     SALTGILERPDLKKLLDRRKRLCLPEQGEYAYLATLEAFRNAGINEDFLEANEVGILYG
                     NDSSAAPVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACA
                     SGSHAIGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDK
                     RRDG"
     aSDomain        957..1442
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg252_2_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.30E-14"
                     /label="ctg252_2_PKS_KS.1"
                     /locus_tag="ctg252_2"
                     /protein_end="226"
                     /protein_start="64"
                     /score="44.1"
                     /tool="antismash"
                     /translation="KRLCLPEQGEYAYLATLEAFRNAGINEDFLEANEVGILYGNDSSA
                     APVINAVDIIREKKNTALVGSGSIFQSMNSTVTMNLSVIFKLRGVNFTIAGACASGSHA
                     IGMGYLLIKSGLQDCILCGGAQEVNPYAVGSFDGLSAFSTQEAAPEKASKPFDKRRDG"
ORIGIN
        1 ataaataaaa tgaaatatgc attagtaacc ggaggaagcc gaggtatcgg ccgtgctgtc
       61 agttgtaaac tggcggaaat gggctacttt atactgataa attatcagaa taatgacgca
      121 gaagcggaga aaacgttgca gttagtacag gaaaaaggaa gtaatggcga gttgatgaag
      181 ttcgatgtga ccgaccctgc cgctatcacc cttgctttgg gcaactgggc ttcccaacac
      241 cctgacgaat atatcgaggt actgataaac aatgcaggta tccgcaaaga caacctgatg
      301 ctctggatga caggagaaga atggagcaaa gtgctcgata tcagcctgaa cggattcttc
      361 aacgtgacac agcctttatt gaagaatatg ctggtcaaac gttatggacg tatcgtaaat
      421 atcgtgtcat tgtcgggcat tcagggaatg cccggccaag ccaattactc cgcagccaaa
      481 ggtggcgtaa tagctgctac caaagcactg gcacaggaag ttgccaagaa gaaagtaaca
      541 gtcaatgcag tagctccggg attcatccgt acggatatga cggaaggaat tgatgagaac
      601 gaatggaaga aacatattcc cgcgggacgt ttcggcactc cggaagaggt tgccgacctg
      661 gtcggtttcc tggcatctcc agcctcatcc tacatcacag gagaagtgat ttccatcaac
      721 ggaggactat atacttaaaa taaaagcata gaatagacaa aataatgaaa agagttgtta
      781 tcacgggaat ggggatttac tcttgcatcg gcaagaatct ggatgaagta aaagactcac
      841 tatataatgg gaaatcggga attggcatag acccggtacg gaaagaattg ggttactttt
      901 ctgcattaac ggggatattg gaacgtcccg acttgaagaa gttgttggac cgccgtaaac
      961 gtctctgtct accggagcag ggagaatatg cttatctcgc tacattagaa gctttccgta
     1021 atgccggtat taatgaggat tttctcgaag ccaatgaagt gggtattttg tatggcaatg
     1081 atagtagtgc cgctcctgtt attaatgcag tggacatcat tcgtgaaaag aaaaacactg
     1141 cactggtagg ttccggttct attttccagt cgatgaattc caccgtgaca atgaacctgt
     1201 cagttatttt caaactaaga ggggtcaact tcaccattgc cggagcctgt gcaagcggtt
     1261 ctcacgctat tggtatgggt tacctgctta taaaatcggg attacaggat tgtattcttt
     1321 gcggtggcgc acaagaagtc aatccttatg cagtaggaag tttcgacgga ctaagcgcat
     1381 tttccaccca ggaagcagcc cccgagaaag cctcgaaacc ttttgataaa cgacgtgacg
     1441 gac
//
