LOCUS       gnlProkkaAGCLPCHE_783   6146 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGCLPCHE_783.
ACCESSION   gnlProkkaAGCLPCHE_783
VERSION     gnlProkkaAGCLPCHE_783
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 11:14:16
            Original ID  :: gnl|Prokka|AGCLPCHE_783
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6146
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6146
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[358:3599]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      359..3599
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..6146
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6146
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             3..374
                     /locus_tag="ctg783_1"
                     /transl_table=11
                     /translation="MDSMQIVWHGEYVRYFEDGREAFGKQYGLDYMSIYREGYMVPIVD
                     LTCQFKQSLSFGEEAIVETRYIACEAAKIKFEYIIYRATDQSIVATGSTIQVFLNLNKE
                     LELMNPPFYLEWKKKWNIL"
     CDS             359..2131
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (125-376). E-value:
                     7.1e-28. Score: 89.5. Matches aSDomain:
                     nrpspksdomains_ctg783_2_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 173.9; E-value:
                     9.1e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg783_2"
                     /sec_met_domain="APE_KS2 (E-value: 1.4e-108, bitscore:
                     352.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYPLNIYITAHTLISSLGFGIPENLEAIHNYRSGIRMQEAGLIS
                     DHPLLAGMIDSVELEKRAKLMQITDYTRMEQLFILAIQEVISQSGADLREPDCTLLLST
                     TKGNIDLLSELPADSPVFLWKMAERIGDFFGATNQVEVISNACISGVSALIVAKRWIES
                     GRYKRVIVAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGN
                     ANHIILSGGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYN
                     DEMESKAIHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLG
                     VPMPITVYTTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLKQKVNLQATDKASAPSV
                     CKAVVESGNMVTIRPGAVESKGTTVFSSSETDFAPFIREAYKHLGENNMKFYKMDNLCK
                     LGYVAAEYLLKNTHHRPEEIGIILANASSSLDTDCKHQAIISKEGDKAASPAVFVYTLP
                     NVVLGEICIRHKIQGENTFFVRRQSDAASLEDYARIVMAKGKLRTCIIGWCELLDGHYQ
                     AEFKQLNNISTIYG"
     aSDomain        734..1486
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg783_2_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="7.10E-28"
                     /label="ctg783_2_PKS_KS.1"
                     /locus_tag="ctg783_2"
                     /protein_end="376"
                     /protein_start="125"
                     /score="89.5"
                     /tool="antismash"
                     /translation="MAERIGDFFGATNQVEVISNACISGVSALIVAKRWIESGRYKRVI
                     VAGGDILSHFITSGFLSFRSVSAHLCRPYDIQRDGLSLGEACGAVLLETQGNANHIILS
                     GGAISNDANHISGPSRTGDGLALAINQAMEEAGALPEDISFINAHGTATVYNDEMESKA
                     IHLAGLAAVPVNSLKPYFGHTLGASGIIETILCIEQLKEGRYYGTLGYETLGVPMPITV
                     YTTHQPMPMKCCIKTASGFGGCNAALVLS"
     CDS             2124..2405
                     /NRPS_PKS="Domain: PP-binding (22-86). E-value: 1.4e-11.
                     Score: 36.7. Matches aSDomain:
                     nrpspksdomains_ctg783_3_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg783_3"
                     /sec_met_domain="PP-binding (E-value: 2e-12, bitscore:
                     36.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNLDQTKRELMDEVKGKLIEELNLEEITPEDIDNEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVRTLADYIIANRKA"
     aSDomain        2190..2381
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg783_3_PP-binding.1"
                     /evalue="1.40E-11"
                     /label="ctg783_3_PP-binding.1"
                     /locus_tag="ctg783_3"
                     /protein_end="86"
                     /protein_start="22"
                     /score="36.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDNEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     ENPSEGKQIFYSVRTLADY"
     CDS             2409..3599
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (77-388). E-value:
                     1.8e-36. Score: 117.8. Matches aSDomain:
                     nrpspksdomains_ctg783_4_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 257.7; E-value:
                     3.4e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg783_4"
                     /sec_met_domain="APE_KS2 (E-value: 6.3e-129, bitscore:
                     419.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALRQRKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLISLPPQRTVSRTALLGMIAAKEAMKDAGLTPPLRIGFISATSVGG
                     MDLSEHFYESFKKNPGQGRLREVISHDCGASTELIASYLGINDFITTISTACSSAANAI
                     MLGARMIKHGLLDAAIVGGTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAG
                     YLVLQSESSLQRTPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEKID
                     YINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDK
                     GLIYPNLNFTDAMPETGLIPETSFQEGIPIRHVLSNSFGFGGNDSSLLFSATNFPA"
     aSDomain        2640..3572
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg783_4_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.80E-36"
                     /label="ctg783_4_PKS_KS.1"
                     /locus_tag="ctg783_4"
                     /protein_end="388"
                     /protein_start="77"
                     /score="117.8"
                     /tool="antismash"
                     /translation="AAKEAMKDAGLTPPLRIGFISATSVGGMDLSEHFYESFKKNPGQG
                     RLREVISHDCGASTELIASYLGINDFITTISTACSSAANAIMLGARMIKHGLLDAAIVG
                     GTDALCRFTLNGFNSLMILDKTHCRPFDRSRTGLNLGEGAGYLVLQSESSLQRTPYCEL
                     SGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISLEKIDYINVHGTGTPGNDASEGM
                     ALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGLIYPNLNFTDAMPETGL
                     IPETSFQEGIPIRHVLSNSFGFGGNDSSLL"
     CDS             3624..4622
                     /locus_tag="ctg783_5"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPPKDHSPGNNRPYLQACEPDYKDIITNATLRR
                     RMSRIVKMGVACGLECMGELSPEKIQGIITATGLGCLTDTEKFLNNLLDNEERMLNPTP
                     FIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIGEGSENILVGAIDEM
                     TETSYTIQQRLGVLKGIAAGEGAQFFLLSREAGEHPLAEIQGIETFIGKQTTEEISSRI
                     IRFLQRNGLECQDIQWLVTGKNKKPHNQDDSHEQTVDNGNSIYEELETNLFPESVHLSF
                     KNECGEYPTATSYAVWKAVNESANCTTSTHILIYNHHHSINHSLILIRKSV"
     CDS             4619..5296
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 127.7;
                     E-value: 9.3e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg783_6"
                     /transl_table=11
                     /translation="MIIVCLLLCLLLLLSFLVYASYSIQSGIYLRSFCKKHTAEKIVAL
                     TFDDGPDSLQTPKVLQVLKEYQVTACFFCIGHKVKGNEAILQKMVAEGHLIGNHSHTHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVSLFRPPFGVTNPTIAKAVRQLGYTPIGWS
                     IRTLDTQQAPDKVLARIRKHLEPGAIILLHDRMPDSDQLVKQILDLLKEQGYTVVRPDK
                     LLA"
     CDS             5310..5945
                     /locus_tag="ctg783_7"
                     /transl_table=11
                     /translation="MRTLLIYLSLFFLSIASMHAQSMKKMAQKTEFESRLAKEAQTVES
                     IESDFTQVKYLDVFDEKVTSKGKFYYQKTHKICMEYFRPMDYLIVINGSKLKIVSDGKK
                     SIMNLSSNKMMAQMQDMLTACMIGDLSKMSSNYLLEYFEDARYYLVKIKPTNKAVQAYI
                     AGIEIYLDKKDMSVHKLRLSETATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             5920..6144
                     /locus_tag="ctg783_8"
                     /transl_table=11
                     /translation="MRRSLRFVSLMVLLFLWIQIQTSCSPRMSGEGSTVLPAIELTQGE
                     SSQKYNIQLDFMKHHMSGMLIVRRMPDNEI"
ORIGIN
        1 aaatagactc catgcagatt gtatggcatg gtgagtatgt gcgctatttt gaagatggaa
       61 gagaagcttt tggcaaacag tatggtttgg attatatgag tatttaccgg gagggataca
      121 tggttcctat cgtggattta acctgtcagt tcaaacaatc actatctttt ggtgaagaag
      181 cgattgtcga aacgcgctat attgcctgtg aagcagccaa gataaaattt gaatacatta
      241 tctaccgggc taccgaccag agtatagtag ccaccggaag caccatacaa gtgttcctga
      301 acctgaataa agaattggag cttatgaatc ctccgtttta tctggaatgg aaaaagaaat
      361 ggaatatcct ttaaatatat acatcacagc ccatacgctg attagttcgt taggtttcgg
      421 catcccggaa aacctggagg ccatccataa ctaccgaagc ggaatccgta tgcaagaagc
      481 cggcctaatt tccgatcatc ccctattggc gggaatgatt gattctgtgg aattggaaaa
      541 acgggcgaag ctgatgcaga ttacggatta tacccgaatg gagcaattat tcatactggc
      601 tatccaagag gttatttctc aatcgggagc cgacttgcgg gagccggatt gtaccttgtt
      661 attatctacc actaaaggaa atatagattt attgagtgaa ttacctgctg acagtccggt
      721 ttttctttgg aaaatggcgg aacgaatcgg agatttcttt ggagcgacaa atcaggtaga
      781 ggtcatctcc aatgcctgta tatcaggagt ctcggcacta atcgtcgcta agagatggat
      841 agaatcagga cgttacaaac gagtgattgt ggcaggtggg gatattcttt ctcatttcat
      901 taccagcggc tttctatcgt ttcgatctgt cagcgcacac ctttgccgac catacgatat
      961 acaacgggat ggattaagtc tgggcgaagc ctgtggagct gttcttttag aaactcaagg
     1021 aaacgcgaat catattattc tctccggagg agcaatcagc aatgacgcca accatatatc
     1081 cggtccttcc cgaacagggg acggtttagc tctagccatt aatcaggcaa tggaagaagc
     1141 cggagcactc cccgaagaca ttagctttat caatgcacac ggaacagcta cggtttacaa
     1201 tgatgaaatg gaatccaaag ccatacatct ggcgggatta gctgcagttc cggtgaatag
     1261 cctcaagccc tatttcggtc atacattagg agcttcgggc attatcgaaa ccatactttg
     1321 catagagcaa ctaaaagaag gaagatacta cggaacttta gggtatgaaa cactcggtgt
     1381 tcccatgcct atcactgtct ataccactca tcagccgatg ccgatgaaat gctgcatcaa
     1441 aaccgcttcc ggtttcggag gctgtaatgc cgcactggta ttatccctcc ccgatgctca
     1501 cctgaaacag aaagtaaact tgcaggcaac cgacaaagcg agtgctccgt cagtttgcaa
     1561 agcagtggtg gaatcgggca acatggtcac aatcaggcca ggagcagtag aaagtaaagg
     1621 aacaactgta ttcagctctt cggaaactga ctttgcaccg ttcatccggg aagcatacaa
     1681 gcatctggga gaaaacaata tgaagttcta taagatggac aacctctgta agctgggata
     1741 tgtagctgcc gaatatttac tgaaaaatac acaccaccgt ccggaagaga ttggaatcat
     1801 tcttgccaat gcttcttcct ctctggatac ggactgcaaa catcaggcaa tcatcagtaa
     1861 agaaggggac aaagcagcca gtcctgccgt gtttgtctac actctcccca atgtagtatt
     1921 gggagaaatc tgtatccggc acaagattca gggagagaat acattctttg tccgtcggca
     1981 atccgatgct gcctcattag aggattatgc aaggattgtg atggcaaaag gtaagttacg
     2041 cacctgtatc ataggctggt gcgaactact ggacggacat tatcaagcag aatttaaaca
     2101 acttaataat atatcaacga tttatggata atttagatca aaccaaaaga gaactgatgg
     2161 acgaagtgaa agggaaacta atcgaagagt tgaaccttga agaaatcact ccggaagata
     2221 ttgacaatga agcccctctg tttggcgacg aaggtcttgg ccttgactcc attgacgcac
     2281 tcgaaatcat cctgattctg gaacgcgaat acggtataaa gatagagaac cccagtgaag
     2341 gaaaacaaat cttctactcg gtacgtacac tggcagacta catcattgct aatcgcaaag
     2401 cttaaccgat gaagatatac gtcaccggat tgggagttgt ttcgggcatc ggtatcggag
     2461 tttccgaaaa tatagaagcg ttgagacaaa gaaagcatgg catcggaaaa gtaactcttt
     2521 ttccgactgc tctcgatgtg cccgtatccg aagtgaaacg tagcaatgag gaactaaagc
     2581 aactgatctc tttacctccg caacgcactg tatcacgtac ggccttgttg ggaatgatag
     2641 cagccaaaga agcaatgaaa gatgcgggac tcacaccacc attacgtatc ggttttattt
     2701 ccgccacttc cgttggcggc atggatttga gcgagcactt ctatgaatct ttcaagaaaa
     2761 acccgggaca gggacggtta cgggaagtaa tttcacacga ctgcggagcc agtacagaat
     2821 tgattgcttc gtatttgggt atcaatgatt ttataaccac catcagtaca gcctgctcgt
     2881 cagcagccaa tgccatcatg ctgggagcaa gaatgattaa acacgggcta ctggatgctg
     2941 ctatcgtggg aggtacggat gcactttgcc ggtttacgct caatggattc aactccctga
     3001 tgattttgga caaaacacat tgccgtccct ttgaccgctc acgtaccgga ttaaatctgg
     3061 gagaaggtgc cggttactta gtgcttcaat cggaaagttc actccaaaga actccttatt
     3121 gcgaacttag cggttacgcc aatacgaatg aggcttatca tcaaacagga agttctcctg
     3181 aaggggacgg tgcctttctg tcaatgagtg aagctatcgc ttccagtggt atttcccttg
     3241 aaaaaatcga ttatatcaat gtacatggaa caggtactcc cggcaatgat gcgtcagaag
     3301 gcatggcgct ccgaagaatc tttggagaac acgttccgcc atttagttcg gtaaaagctt
     3361 ttatcggaca taccttagga gcttccgaag gaattgaagc tgtttactcc gttctttcaa
     3421 tagataaagg gctgatttat cccaacctga actttacgga tgcgatgccg gaaacaggac
     3481 tgataccgga aacctctttt caagaaggaa tccccatccg acatgtgtta tccaactctt
     3541 tcggtttcgg aggaaacgat tcatcgctcc tcttttccgc aacgaatttt ccagcataaa
     3601 cgcaccttta agtatttaag cctatgcagc cagtttatat tcaacgcatc gcttccattc
     3661 atccgccaaa ggatcattca ccaggaaata atcgccctta tcttcaggct tgcgaacccg
     3721 attataagga tattatcacc aatgcgacct tgcgcagacg catgagccgt atcgtaaaaa
     3781 tgggggtggc ttgcggattg gaatgtatgg gtgaactatc tcctgaaaag atacaaggaa
     3841 tcatcacagc aacaggattg ggctgcttga cagatacgga aaaattcctg aacaacctat
     3901 tggataatga agagcggatg ctgaatccta ctccttttat ccagtcgaca ttcaatacaa
     3961 tcggtgcaca aatagctctg attcatcaaa tacatgccta caacatgact tatgtccacc
     4021 gtggtcttag ttttgaaagt gctttattgg acgctatgat gaaaatagga gaaggaagcg
     4081 agaatatact tgtgggagcc atcgatgaaa tgacagaaac cagttacacg attcagcaac
     4141 ggctgggagt gctgaaaggg atagcagcag gagaaggtgc tcaattcttc ctgttaagtc
     4201 gggaagccgg agagcatccg ttggctgaaa tacagggaat cgaaactttc atagggaaac
     4261 agactacaga agaaatcagc tcccgaatca tccgtttttt gcaacgaaat ggtttagaat
     4321 gtcaggatat tcagtggttg gttaccggga aaaacaagaa gccacacaat caagatgact
     4381 ctcacgagca aactgttgac aatggcaact ctatttatga agagcttgaa acaaaccttt
     4441 tcccggaaag tgttcatctt agttttaaga atgaatgtgg tgaatatcct accgcaacat
     4501 cgtatgcggt atggaaagca gtgaacgaat cggccaactg cactacctcg acccatatat
     4561 tgatttataa tcatcaccac tccatcaatc attcattgat tctaatccgg aaaagcgtat
     4621 gataatcgtt tgcctccttc tttgcttgct cttgctcctg tcttttctcg tttatgcctc
     4681 ttatagcatt caatcgggaa tttacctccg gtcattttgc aaaaagcata ctgcggaaaa
     4741 gattgtcgcc ctgacttttg atgacggccc cgactcccta cagactccca aagttctgca
     4801 ggtactaaaa gaatatcagg taaccgcctg tttcttctgt atcggtcata aggtaaaagg
     4861 gaatgaagca atcttgcaaa aaatggtggc agaaggtcat ctgattggaa atcattcgca
     4921 tacccattcc ggtttattcc cgctatacgg gctctccaag atgaaaaaag acttgcaaac
     4981 ttgtcagtgt gaactagaac gagtaacttc gcagccggtt agtttgtttc gtccgccgtt
     5041 cggtgtcact aatccaacga ttgcgaaagc cgttcgacag ttaggatata cccctatagg
     5101 atggagcatc cgtacactgg atacacaaca agcaccggat aaagtccttg ccaggattcg
     5161 gaaacatctt gaaccgggag ccattattct gttgcacgac cggatgcctg acagcgacca
     5221 gctagtgaaa caaatcttgg atttgctgaa agaacaagga tataccgttg tccgtccgga
     5281 caaactattg gcataaaata aaaaaaggta tgagaacttt attaatatat ttatcgcttt
     5341 tcttcttgtc aatagcctct atgcatgccc agagcatgaa aaagatggcg caaaagacag
     5401 agtttgaaag ccgcctggca aaggaggcgc aaaccgtaga gtccatcgaa agcgatttca
     5461 cccaagtgaa atatctcgat gtattcgatg agaaggttac ttccaaaggg aagttctact
     5521 accagaagac ccataaaatc tgcatggaat atttccgccc gatggattat ctcatcgtga
     5581 taaacggcag taagctcaaa atcgtttcgg atggcaagaa aagtatcatg aatcttagtt
     5641 cgaacaaaat gatggcacag atgcaggata tgctgaccgc gtgtatgata ggcgacctgt
     5701 ctaaaatgtc gtccaactac ctgctggagt attttgaaga cgcacgatac tatctggtta
     5761 aaataaaacc gaccaacaaa gcggtacaag cctatattgc cggtatagaa atctatctgg
     5821 acaagaaaga tatgtcggta cacaaactcc gtctgtccga aacagccaca aactatacag
     5881 aatacgaatt ctataataaa aagttcaact ccctgaagaa tgagacgaag tttgcgattc
     5941 gttagtctga tggttctgct gttcttatgg atacagatcc agacttcctg ctctccacgg
     6001 atgagcgggg aaggaagtac tgtgctcccc gctatcgaac taacacaagg agaaagctcg
     6061 caaaaataca atatccaact ggatttcatg aaacatcaca tgagcggtat gctaatagta
     6121 cgccgtatgc ctgataacga aatccg
//
