LOCUS       c00056_gnlPro..        13296 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EGHMHIGH_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 09:52:00
            Original ID  :: gnl|Prokka|EGHMHIGH_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13296
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13296
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[337:3296]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      338..3296
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13296
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13296
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..125)
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCL"
     CDS             338..2566
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_2"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2571..3296
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_3"
                     /sec_met_domain="Radical_SAM (E-value: 2.5e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3528..4790)
                     /locus_tag="ctg56_4"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVEMGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4842..5390)
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LLHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5578..6330
                     /locus_tag="ctg56_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6435..7361)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.4; E-value: 35)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg56_7"
                     /sec_met_domain="LysR_substrate (E-value: 7.4e-47,
                     bitscore: 151.1, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.4e-18, bitscore: 57.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIQQLEYILAVDQFRHFAKAAEYCRVTQPTLSAMIQKLEDELGV
                     KLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKEIISEEQHSLSGTFRLAVLPTIAPY
                     LLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTGEADAAIIASMLDDAALTEETLFYE
                     QFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGHCFRDQLVRFCQMEAVKISQMAYRL
                     GSMETFMHMVESGKGITFIPELAVMQLSEEQKELVRPFAIPRPTRQIVLVTRKDFIRTS
                     LLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7503..7976
                     /locus_tag="ctg56_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8080..9078)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.2e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9133..10401)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_10"
                     /sec_met_domain="MFS_1 (E-value: 3.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10651..11664)
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTTALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFLVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11687..12823)
                     /locus_tag="ctg56_12"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 gagagacagg gattcgaacc ccgggtacct cgcagtacaa cggttttcaa gaccgccgca
       61 atcgaccact ctgccacctc tccagaacta cggttaagta gtgcttttct cttaaagcgc
      121 tgcaaaggta cgaatcattt tttaacttgc aaattattcc gcaaaaaaat attagaaaag
      181 tatatttgga agtaataacc gccctctggc ttctccccat aaataggtat ttttatgcta
      241 ttcaacataa aataggaccc ttttatatac ctaaaccgaa aaaaggttgt aaatttgcgc
      301 gctctaaagg ataactaacc actaactgat taattttatg gaactgaata agacctttaa
      361 agatggactt tggagcaaag aaatcaatgt aagggatttc gttagtaaca acatcactcc
      421 ttatgaaggg gatgcttctt tcctgcaagg acctaccgaa cgcaccaaag ctgtctggaa
      481 tcactgtctc aaagctctcg aagaagagag aaacaataat ggtattcgtg cactcgacta
      541 cacaactgta tctactataa cctctcaccc tgccggctac atcgataaag aaaacgaact
      601 gatcgtcgga ctacagaccg atcaggtgtt aaaacgtgcc atcaaaccgt ttggcggaat
      661 caatgtggtt atgaaagctt gccgtgaaaa cggagtggaa gtagatgaca gagttaagga
      721 tatcttcact cactatcgca agactcataa tgatggggta ttcgatgtgt ataccgaaga
      781 aattcgttcg ttccgttcat tgggattcct taccggactt cccgacaact atgcacgcgg
      841 acgtatcatc ggtgattatc gccgcctggc tctctatggt cttgaccgtc tgatagaagc
      901 taaaaaagaa gatctgcata atctgacagg tcctatgact gaagcccgca ttcgtcttcg
      961 cgaagaagta gccgagcaaa tcaaggccct gaaagagatt aaagtattgg gcgaatatta
     1021 tggtttggat ctgagccgac cggcatatac cgcacaggaa gctgtacaat gggtgtatat
     1081 ggcttatctg gctgccgtaa aagagcagga tggtgctgcc atgtcactgg gtaatgtatc
     1141 ttcattcctc gacatctatc ttgaatatga attaagccag ggtacgataa ccgaaacatt
     1201 cgctcaggaa ctgatcgacc aattcgttat caaactccgt atggtacgcc acttgcgtat
     1261 gcagtcgtac aacgatattt ttgcgggtga tcccacatgg gtgaccgaat ctatcggtgg
     1321 acgtttcaat gacggacgta ccaaagttac taaaacttct ttccgcttct tgcagacact
     1381 ttataactta ggcccgtcac cggaacctaa catgactgta ctatggagcc ctgagttacc
     1441 cgaaggtttc aaagcattct gtgcacaagt atctatcgac acttcttccg tacaatacga
     1501 aaacgacgac ctaatgcgtg aagtccgtca atcggatgac tacggaatcg cttgttgtgt
     1561 ttcatatcag gaaatcggaa agcagattca gttcttcggc gcacgtgcca accttgccaa
     1621 agccctgcta ctggctatca acggaggacg ttgcgaaaat acaggtacag ttatggtaaa
     1681 agacatccct gtattgaccg gtgaaacact gaagttcgaa gaagtaatgg ccaactataa
     1741 gaaagtattg atacaaattg cacgtgtata caacgaagca atgaatatca tacattacat
     1801 gcacgataag tattactacg aaaaggcgca gatggctttc gtggatactg atccccgcat
     1861 taacctcgct tatggtgtag ccggactttc aatcgccatc gattcactgt ccgccatcaa
     1921 atatgcacat gtgaaagccc gtcgcaacga catcggactg acggagggat tcgatatcga
     1981 aggtgctttc ccttgtttcg gtaatgacga tgaccgtgta gaccacctgg gtgtagacct
     2041 ggtatatttc tttagcgaag aattaaagaa actccccgta tataagaatg cccgtcctac
     2101 cctctcgctg ctgactatca cttcgaacgt aatgtatggc aagaagaccg gtgccactcc
     2161 tgacggacgc gccaaaggca ttgcctttgc tcccggtgcc aaccccatgc acggacgtga
     2221 taaaaatggt gcaatcgcct cactgagttc tgtagccaag ttgcgttatc gcgactcaca
     2281 ggatggtatc agcaatacat tctcaatcgt tcccaaatca ttgggagcaa cacaagaaga
     2341 ccgtatcgac aatctggtga ccatgatgga cggatatttt acaaaaggcg cacaccacct
     2401 gaacgtaaac gtgctgaacc gggaaatgtt gcaggatgcg atggaacatc ccgaaaagta
     2461 tccgcaactg actatccgtg tctcaggata tgccgttaat ttcgtgaaat tgagccgcga
     2521 acatcagttg gaagtaatca gccgcagttt ccacgaaaga atgtaattga atgataaacg
     2581 tacactcata cgagtcaatg ggaacattcg acgggccggg tctccggctc gtcgttttcc
     2641 ttcaagggtg taacttccgt tgcctctatt gtgccaatcc ggacacaatt gaagccaaag
     2701 gagggacagc aaccgaccct gaggaaatag ttcgcatggc cgtcagtcag aaagctttct
     2761 tcggtaaaaa gggaggtatc accttttccg gcggagagcc tacttttcaa gcaaaatcgc
     2821 ttatcccact ttttaaaaga ctaaaggaag caggaatcca tatttgcctt gataccaatg
     2881 gcgggctatg gaacaatgat gtagaggaac tattggaatt gactgatctg gttttattag
     2941 atatcaaaga atttaatccg gaacatcatc agtctttaac cggaagaagc aacgagcaga
     3001 ccctgaaaac cgcagcctgg cttgaaacca atcataaacc attctggttg cgatacgtat
     3061 tagtgcccgg ctacagtgac ttcgaagacg atatccggca gctgggagag catcttggaa
     3121 cgtaccagat gattcagcgt gtagaaatat tgccttacca caccttgggt gttcacaaat
     3181 atgaagcaat gaacaaagaa tatatgctga aaggagtgaa agagaatact ccagagcaga
     3241 tagaaaaggc tgagaaacta ttcaggcaat atttccagac cgtacaagta aattgactta
     3301 tataagtgtc gaaattcgta ttcaccacag attacacgaa tttacacaaa taaagatcat
     3361 tggcaatcaa tagattaagt tcattctgcg gtgaattatg acgactgcac ttatttataa
     3421 ttttgtaagt cacgatataa aagtctccct gttcttgcct taattcatta caatacaagg
     3481 caagaacagg gagataatgt aaccggcata ttttttgcca tcctacttta ataagtgaat
     3541 cgcaatcctg cctgcaagtt aaagttacaa ggcctttctt ttcggatggt ttgtactttg
     3601 gagccatcat caaagaaata cgaaactccc ggttccacat ataggccgac atgatctgtc
     3661 gcattgaatt gcgctcccac ggcaccggct acagaaaatt gcaaaggctt cacattcacc
     3721 ttatcatccg ccaactttcc ataaacacac ttttcaacca ttcctccggc agatacatag
     3781 agtgtaaaat atttcttttc cagaaaattc cagtttccac gtacaggaat acctatataa
     3841 tgcaatttct gactctgcat cttggtatcc ccctgccgtt tgatgtcaga agacaacaac
     3901 gtataagtca atcccatctc tacagaaaaa cctttgggaa gagacttacg tacagacagt
     3961 ccgaagctaa ccggctgatg atgttcataa tccaccacgg cagttgtatt ggacttcagg
     4021 taagggactc cttcttcaaa tataacttcc tgatcggcag gaatactcac agctccattc
     4081 atgatcgtca tcaagtcgac cctgttagtc atcggacggg gcgcaaaatt ttcggaacca
     4141 tttgtcggaa gtccacctcc attaccgata cccactccca tcgaccattt accaccacgt
     4201 ttagcagaag agtctccgat aggcaactga tacttgtctt taccagacgg tcgccgcgct
     4261 tctttcctct ttggaggctg cgccgtcgca ctttcttttt tctcgattgc agcaattgct
     4321 tcctgttgcg gctcagatct cttttcctcc gtcactgcct ccggtcgctt ctctaccagg
     4381 gaggatacct ccggaacaat caccggatca gtattctttg ccaaatagcc cgaaacaggg
     4441 ttaatactcg tcgttcctac cggcttaact ggttcggata cagctacctg tacatccggc
     4501 aaggcaggtt ccggcaatac atccgggttg acagccagtg aaggagccgt tgcataacgg
     4561 atttcatcag ctaccggact attcagaaaa tacaaactga cagcagtcgt tagcaccaat
     4621 accacagctg ccgcagcaac cgcccaccgg cgatacggat atattcgttt ttcggttaca
     4681 ggcatcagtt ccctttccag tcgttcccaa ccggaagcag gcatcggctc cgaataatct
     4741 tcgagcttat ccttgaatgc tttaatccat ttttcgtctt ctttcatcat tctatttcat
     4801 ttttgaaatc caaggttcac ctcagtatct gtaaatacat gtcaaccatt ggtcaccaac
     4861 cattctttca ctttctttgc caatacactt tttgcacgaa aaagctgtga agcagaagat
     4921 ttttcattaa tccccaacat ctgtgcgatt tccttgtgcg acttatcttc aaaggtgtat
     4981 aaattgaata cggtacgata tccggcgggg agttcattaa taaattgcat cagcactttc
     5041 tgtggtattg cttcaacagc cgaagcatcc ggttcttcat acgtttcggg aacttcatcc
     5101 agtgccgtgg tctggttcat cacgtcgttc tttcttaaga actgtaaagc cgtattcacc
     5161 attacacgct ccatccatgc tctcagagag ccttcacccc gccaggtaaa cttgtcgaag
     5221 gagtcgaaaa tcttcaggaa accgtcgtgt agcaagtctt gtgccatgtc cctgtctccg
     5281 gcataacgaa gacagacacc aagcatgcgc cctgcgtact gctcataaag ttctttgcgg
     5341 gcacgattat ctccctgcct gcaacgttcc gacagctcta attcattcat tctcctaaac
     5401 acgtgtttac cttataaatg cagcaaagat agaaatactg cacagagaga acaactcttt
     5461 tatcactttt gtttctttaa cattttagga tgcaatattt catcacttcc tgcattttct
     5521 caatacaata aagaataaat ctcaatggat aaataggata aaaccaacaa gaaacttatg
     5581 aagaaattta atttaataac ttttgccgtc atcctgatgt tattgcccat tttacagtca
     5641 tgtctggacg atgccaacaa cgacgagtgg gtcacttgtc ctccgggtgg aatattagcc
     5701 atcggcacaa tgaagattcc caatgcggac actccaaggg actttttcat tgcgttggac
     5761 aatggagaca atgtacttcc ggcagatacg gccgatatac gcaacaggaa atacactgtt
     5821 gcagaaggtc aaagagtctt cgttggctat ctgcagatgg gagaagagaa acccggatat
     5881 gagaacggta aaatattcac gatagaagat atattgacga aagagatcat tccactgacg
     5941 gaagctacag cagacagcat tggagacgac cgtatcaacg tcacagcgca tgcacttacg
     6001 aaagattatc tgaccatcga atatcaatat ctgggcagca tgaatgaaaa taaaaaacac
     6061 atgctgaact tggtacaaaa cgaaataaca ggtcccataa aagatgacgg atatatctat
     6121 ctggagttcc ggcataatgc ctttaatgac tcccccaatc aattgggttc gagccttgtt
     6181 tctttcaagc tggatagtat agccgagcaa ttggcgacag ccaaaggaat aaaactccgt
     6241 gtgaacacca tttatgacaa tatacagtat gtcacaatag atatcaacga agacaaaaac
     6301 ttaaaaataa aatcatttca ttctcaataa aacaacaaga aacacctaca caatcaggca
     6361 aaacgagtaa taattctgat acataaaaga aataaggcgg cgatgtttgt gaaaatatcg
     6421 ccgtcgtttt tatattatac cagacactga acggcctgca gggtaagcat ctccttggga
     6481 accgccgcct gaatctcctc tttcaaaacc tgcagcagac tggtgcggat gaagtctttc
     6541 cgggtcacca ggacaatctg acgggtaggc cgcgggatag caaacggacg gaccagttct
     6601 ttctgctctt cgctcaattg catcactgcc agttcgggaa taaacgtaat ccccttacca
     6661 ctctccacca tatgcataaa ggtttccata ctacccagcc gatacgccat ttggctgatc
     6721 ttaaccgctt ccatctgaca aaaacgaacc aactgatcgc ggaagcaatg cccttcgtca
     6781 agaagccaaa gccgttcccc tgtcacatcg gacgtacgaa tcacatcgtg cttgaacaac
     6841 ggttccttct ttgagacata gcccaggaat tgctcgtaaa ataaggtctc ttccgttaat
     6901 gcggcatcat ccagcatgct ggcaatgata gcagcatccg cttcaccggt cagcagagcc
     6961 ttgcgaatgt cgggcgtctt catctccatc acccgtatat caagatccgg gtatttctcc
     7021 atcagttgcg gaaagaaacg gggcagaaga taaggtgcaa tcgtcggtaa cactgccaat
     7081 cggaatgtac ccgacaggga gtgctgttct tcgctgatga tctccttgac acagataact
     7141 tccgaaagaa tcttacgggc ctgttccagc actttcttac caatggcagt agggcaaacc
     7201 ggtgtcatgc tacggtcgaa cagtttcacc cccaattcgt cttccagctt ctggatcatt
     7261 gcactcaaag taggttgcgt cacccggcaa tactcggcag ctttagcaaa atgccggaac
     7321 tggtccacag ccagaatata ttccaattgt tgtatagtca tcgttctctg atttattaaa
     7381 gatatagaat ctatcaatgc aaagatagaa attttcagtt tgacacgaat cattttgtgc
     7441 cgtatctttg ttccagataa aaagaagaaa tatagtatta actcaaaaaa aacaatatca
     7501 ttatgaagac tttaaattat acacatttgg aagaaaaagg agctaacacc atcgtactgt
     7561 cattacagca actgcttgcc gattttcaga ttcattatgc aaacctgaga ggatttcact
     7621 ggaacatcaa aggacacggt ttcttcgtac tgcacagcaa gtttgaagat ttatataatg
     7681 gagccgccga aaaggtggac gaaatagccg aacgtatact gatgctggga ggaactcccg
     7741 ccaataaata cagtgactat ctgaagatgg cgcagatcaa ggaagtggac ggagtgaata
     7801 aggccgacga cgctctgaat catattctcg aaacttacgg gcatctgatt gcggaagaac
     7861 gtaaaatcct gtctctcgcc tcttcacaca acgacgaagt aacagtggcc atgatgagcg
     7921 actacctgaa agaacaggaa aagatggttt ggatgctgac tgcatacaac ggataacagc
     7981 cgaaagggtg tagccatctg accgaaaagg tgtagccata caaacaaaag ggtgtagcca
     8041 tcccggcggg atagctacac ccttcctgtt ttattcgatt cagatgatac ttgtacgttt
     8101 ggtaaattca ataatctccg gaatgtatcc gaatgcgagc ccggtcactg tatccgcaca
     8161 cccataatag atggcaatcc gtccggtctc cgaatcatga agcgccgcgc atgggaaaca
     8221 gacattaggc acatcaccca tacattcgta atccttctga ggtgaaatca gataaggccc
     8281 cgaacggaat tttactttcc agggctgatc gatgtcaagc agtgccgaac caaaactata
     8341 cacaaaaccg ttgcaggaag ccaatacacc atgatagatc agtaaccagc cttccgaggt
     8401 ttcaatcggg ataggccctg caccgatctt ggtacactgc caggcactgt cttcgaacgg
     8461 agccggcgac ataacatgac gatgacgtcc ccaaaactcc atatcgggag actcgctata
     8521 gaaaatatct ccaaaaggag tatgcccatt atcactcggg cgactcaaca tcgcaaaacg
     8581 accgtttatc ttacgaggga acaagactcc attccgattg aaaggaataa aggcattctc
     8641 caactggtga aaagtaacaa aatcataggt gtaggccaca ccgatagtag gaccatgata
     8701 gccattacac caggtcacat agtagcggtc ttcgataaag caaacccgtg ggtcatatcc
     8761 atagacccag gttccaacct cagcatcatc acattgaaac tttaacggtt cttcgttgat
     8821 atcccaatga acagcatcct tgctgaatcc cacatgcaaa cgcatgcgac gattagtatc
     8881 atcacaacgg aacacccctg catagccatc cttaaacgga actacggcac tgttgaatat
     8941 actgtttgaa gtagggagca agtcgcgcgg aataatcgga ttggccgaac aacgccacac
     9001 tacatcttta catcctgccg gacgttcttc ccaaggcata gctggcaaag cagcacctgc
     9061 aattttaatt tcttccatga ttcgattaaa ttaatattat gtatatatct tgtttatatt
     9121 gaaaatctct ttttatttct tctttccgtc cggatatgtg aaaggtacca gccaagtcac
     9181 gataaaagcc ggtatggtag cgataagtac ccagataaag aaatcgcgat aacccagcca
     9241 atcgctcagg tatccgctca tcattccggg aagcatcacc cccagattca taataccggt
     9301 agcaaaagca taatgtgcca tctgatgttt gccgggagcc acttgctgca tcataaagag
     9361 catcaatccg acaaaaccaa acccgtaacc caagtattca gacacaatgg ccataccaat
     9421 aatccataga tcggaaggct ggtaaagggc taacaggaaa tataccaaga acggaatatt
     9481 aaaagcgcaa cataaagaaa acaaagtctt ccgaagtccg aaagccgaaa tgtaataacc
     9541 ggccaaaagc gaaccgagaa taaaagctcc cgctccgaac gtaccatata ccagtccgat
     9601 atcctgagtg ctgagtccca atccaccatc cgcaaccgac gctttcagga acaacggtac
     9661 aatcttgatg gcatatcctt cggcaaaccg gtacaaaatg ataaagacaa tgtagaaagc
     9721 aatatgtttt ttttggaaaa aagagcggat gacttcccaa agcatattca atgcgtcact
     9781 catcgtattc acttcaccgg aagcgcctcc tcccgaaggc aaaatccgga tgtggtaaag
     9841 accgatcaga atcataatac ccgcacacat caacatgaca atcatccagg catgtaccac
     9901 tccaaattca tccttcagca tacctgccag ccaaaccaag cctccgttgg caagtatctt
     9961 ggccagatta taaaaagctc cctgccaacc gatatacttg gcttgctggg tagcagtcag
    10021 ttcagtcagg tatactccgt cacccgcaat gtcatgagtc gcaccactga gagcaatgat
    10081 ccccatcaga gcgatggcat aacgaaaaaa gtcgggcagc ggcagcgaaa gtgctaccaa
    10141 tgcaaatgcc agtccggtaa tgatttccgt agcgacaaca aagtatttct tcgttttaaa
    10201 catttccaga aacggactcc ataaaggctt caatgtccag ggaagcataa tgagagaagt
    10261 ccagaaagca atctgtgcat tcgacacttc catatcggaa aacataagga cagaaaccat
    10321 cgaaagggcc acaaacggca atcccatagc aaagtaaaca gtaggcaccc aacatacagg
    10381 gcttatcggc tttttattca tcagttagtt ttttataata attccatcgg ttaacaattc
    10441 cagtaagcaa agatagggga tattaaaaac ataacccaag attacgacaa gaagttgctt
    10501 tcattattta ataatacaac tcacccggga aaactactaa cctctatcac ccttttttta
    10561 ttaaacttta tcaatacaat acacgcaaag aagcaccgaa gactttcatc cccgatgcct
    10621 ctcgccccct tatctacaat ctaaacacct ctattgcttc acatataaat ttatctcagc
    10681 aaacccggta taattatccg gagtcagaca gtttattctg aattccttta cattcgggat
    10741 aggtggttcg atggccgcat attgcggatc agccccttta aaatttctga aagtcaagac
    10801 tctcgggtaa gtaacccact cggtttcacc ctctttccga accttaatct cagcacttct
    10861 caggttataa cccgatccgt aggcactctg tttagtgacc gaaaatccgg ttaaggtaac
    10921 aggccggtcc agtagcgtat tccaccaaca ctctccggca ttagccactc cccatgtaaa
    10981 ccaagtagta tttatctcac cgtcaatagc cagatgtgca ccatatttgg catcatcatc
    11041 ggcataaaca ttgctgcaac ttacactcca cgcacttcga tctacagcgg accaattccc
    11101 gggtttcgta taactggtat aaagcacgct ggtataaatc cggatataaa ccgtcttcat
    11161 agatgtactg acagcctgtt cgtccatgcc cgtaactcct ttaagcgcca cgggaagcac
    11221 atatccgtca ggattagtca acttttctat attcttcaaa acgaccagaa aagatgaatc
    11281 ggccactgtc tgtcccgttt ttaagacaac ttcacttgtt tcaatggtat aattatcttg
    11341 gggcaacaac ttacatttcg tcttattggc agaattgtaa gtatccactt tcagcgtatc
    11401 tactcccaaa gcggtagtga catcccgcgt aaccggctgt acggcacaca attgtatttc
    11461 aaaatcagaa cggtcggcag tagaggaatt gctcacacaa tccaccacta ccgcagcacc
    11521 catttcggcc cccggtgcaa ctcccgttct gatatatatc ttttgatatt tgtccatttc
    11581 atcatcatcg ttgctgcacg aagccaacga tacaaagcct gttatcaggc agattaaggt
    11641 cacaaaattc aaatgtctat tcatatctta tcttcttttt acatagttat tgcttatcaa
    11701 aacgaacatg ctctttccag acaagagttc ctcctgccac caaatcgtat ccgtgtccgg
    11761 tacagtcggc aaaggcattt cctttacctt catccatttt ccaatagcct atcaggttcg
    11821 gatcggcggg tttcacggca aaatacatgt tggactgaat ttgcgtctgg ctgattgcgc
    11881 tcttccaaag acgcacctgg gccatctgac aattgttgcg gaagtagcta ccgctcgaaa
    11941 ccatgttcat cttgtcgaat cttaccgggc caccctttgt ctgcagagtc acgtcgagca
    12001 ctccgttgat ataaatcgac aataacccgg aagaattata aacgaaggcc agatgatacc
    12061 acttattctt ctcaaacaaa gtcaccgtat tgacctgact tccaagtgtc ttcacctgta
    12121 atgaattata agggatcata gcgtcaccga aacggatata aacctcgtgg tcgctgctgc
    12181 ccgaattaaa tatagcctga ttattaatat cgaatccgtc catctgtacc caagcctcga
    12241 gtgaccattc attggttgtc actccccaca attcgtcctt ggcgggcttc acggcattgg
    12301 tcgtattcat aaacggtaca gactgtatca gcggcttatc cagcaaaatg ataaacttcg
    12361 acgaaagccc gattgtggac accggtccct gaatttctgt gagagatacc ggaatagcat
    12421 acaattctcc gttttcgttt gaataaggtt tcactctaaa ctcactgggg attgcgctaa
    12481 catcgcctgc cgctatcttt atctctttgt cataagtaaa atactgctcg ggaaggactt
    12541 cgtacgaagt ttcattagct tcattgtact ctttaagaat agaaggatct accgtcagga
    12601 cagcagtcac attttcggtt acaggctgtc ccacacgtac ggtcagagta gttgttgtta
    12661 cattttcagg atcaacggta acctttgccg aaccattctc ggatgcttca ttcaaataaa
    12721 tcgcattgtc gataacctgg taatcggcat cgttgcatcc tgccaggatc atcggcagaa
    12781 cgaaacaggc aagcaaacat tgttttattg ttattctttt cataatcaaa ttctttaaag
    12841 tcattttaca gcaggattca ttattctgat tgcttcacgc aggtacttat attcgatgtc
    12901 gcccggatag tcatattcca tgtgataggt gcctactcca cccttccgta cctgttttcc
    12961 gtcaatagtc ggagtccagc gtgccatgcc ggcaagtgct ctcattttgt ttccgtaacg
    13021 atctacataa tcacctcctc ctgtcggagc ataagattcg aaattctccg taacgatgta
    13081 catattagcc actttctccg gaggaagtat tcctttaaag ttggcaatcg taccagccag
    13141 acgtctgtca agattagcgt cggaattacc cgcaaggtta gagtatgcct gcacaatgaa
    13201 atagtcaaag taaggcccgg tttccggatg aatactttga ggctcgccat caatcacaag
    13261 taaccgtccc gtacccgatt taggtccgat tctttc
//
