LOCUS       c00264_gnlPro..        11166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPJHGKPK_264.
ACCESSION   c00264_gnlPro..
VERSION     c00264_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:54:39
            Original ID  :: gnl|Prokka|IPJHGKPK_264
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11166
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11166
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6594:11164]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6595..11164
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11166
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11166
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..314
                     /locus_tag="ctg264_1"
                     /transl_table=11
                     /translation="LLLPLLLGGCSSDDQSDDNNSPLIGSWISIDDDVEIFYLDLKKDG
                     TGKWTGTYAGEVENVLRLTWSATETTYHVKYENGNSETKQYRIEGNRLYLGDVIYTRK"
     CDS             complement(328..1602)
                     /locus_tag="ctg264_2"
                     /transl_table=11
                     /translation="MATVKIIILKHQRREDNTWNVKIRITHERQSSYIATTHYVGSELI
                     NKKTFELKERNNPIYDQVMLDVLKIRAELSKLGHSIDLYSAKGLCELMKDKLSNKPEGI
                     NFFDFGYAYADKVLKEGRRIGENYRIAISKFEAFVGNRNLCFSDITSSLLIKFEEDLKS
                     QRSKCGIGNISDSGVRLYMSKIQALFNRAKLEYNDEDAGIIRISNNPFAKYKIPKQPIT
                     RKRSLTDEQIRAIKEYRIPENMLGVIIARDVFLMSFFMVGMNTVDMFYLNPPVDDRFEY
                     ERRKTRTRRDDRAFISIKVEPELEPYLERYKDSVGDRAFNFFIRYASHKQFVHKVNLNL
                     KKIGNALGIPDLTLYAARHSWATIARNDCGISMDDVATSLNHKSGYNVTDTYVKKDWSR
                     IDKANRKVIDFVFHPKKKDEEKAGE"
     CDS             complement(1738..2367)
                     /locus_tag="ctg264_3"
                     /transl_table=11
                     /translation="MLSDGDFQYIPYLFISMLANLDRYKIVLASNSPRRKELMTGLGVD
                     YVVKTLPDVDESYPDTLQGEEIPLFIAREKAAAYQSMIGPEELLITADTIVWHEGKALG
                     KPVGRQDAIEMLWSLSGKSHQVITGVCLTTREWQKCFAAVTDVRFAILDEDEIAYYVDH
                     YQPMDKAGSYGVQEWIGFVGVESISGSYFNVMGLPVQKLYRELLKL"
     CDS             complement(2351..2872)
                     /locus_tag="ctg264_4"
                     /transl_table=11
                     /translation="MSTINYDLTRIKALVFDVDGVLSANVIPLHPSGEPMRTVNVKDGY
                     AIQLAVKKGLRIAIITGGRSDVVRKRFIGLGVSDLYFGSAVKIHDYRGFRDKHGLTDEE
                     ILYMGDDVPDMEVMRECGLPCCPKDAVPEVKAIARYISYADGGYGCGRDVVEQVLKAQG
                     QWLSDDAFGW"
     CDS             complement(2893..3684)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg264_5"
                     /sec_met_domain="F420_oxidored (E-value: 2.2e-14, bitscore:
                     43.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTEESAR
                     ELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPM
                     NVWEGHVPHYGVFYPMQTFSKQREVDFKEIPFFIEASSTEDAAFLKAIASTLSNRVYDA
                     DSEQRKSLHLAAVFTCNFTNHMYALAAELLKKYNLPFDVMLPLIDETARKVHELEPKTA
                     QTGPAIRYDENVIGNHLRMLADDPAMQRLYELLSRSIHERQ"
     CDS             complement(3681..4013)
                     /locus_tag="ctg264_6"
                     /transl_table=11
                     /translation="VSAVKANNKDTYKATAVTLIVMGVLYLIDKLIHFSTLGIPWVMNK
                     DNLLLYTAVIFLFIKRDKSVGLVLLGLWLVLNIGLIVSLLGSMSGYLLPLALLIIGGIL
                     YLISTR"
     CDS             complement(4016..4513)
                     /locus_tag="ctg264_7"
                     /transl_table=11
                     /translation="MRKFTGEELSQEDVVALLKAALMAPTSKRSNSWQFIAVDDKKLLS
                     ELSHCKEQASAFIADAALAIVVTADPLASDVWIEDASIASIMIQLQAEDLGLGSCWVQV
                     RERYTATGMPSDEFVRGVLDIPLQLQVLSVIAIGHKGMERKPFNEDHLQWEKIHINKFG
                     GK"
     CDS             complement(4719..5261)
                     /locus_tag="ctg264_8"
                     /transl_table=11
                     /translation="MLEEILEFNKKFVENRGYEKYITNKYPDKKIAILSCMDTRLTELL
                     PAALGIHNGDVKIIKNAGAVISHPFGSVIRSLLVAIIELGVEEVMVIAHSDCGACHMNS
                     DEMIAHMKKRGIKSETIDMIRYCGVDFNSWLGGFDDPVKSVRGTVRSIENHPLIPKDVR
                     VHGFIIDSLTGELTRVE"
     CDS             5379..6362
                     /locus_tag="ctg264_9"
                     /transl_table=11
                     /translation="MPLKLTTYYQGSEIPDFPGTNTFHSKELFQIYEETPGYTPLLIMA
                     SEDGKPVARLLAAIRKSIRMFPPAFIKRCEIYGTGEYLIAEADKERIFSEMLEHLTTEA
                     LRNSFLIEFRNLENAMFGYKYFRSNRYFPVNWLRVRNSLHGIENAEQRFSPSRIRQIKK
                     GLKNGAKVDEARTVEEIREFSNMLRHLYSSRIRKHFPNIIFFQHMDTRLIHSRQAKIFI
                     VRYKDKIIGGSACIYSGNDAYLWFSGGMRKTYALQYPGILAVWKALQDAHQNGFRHMEF
                     MDAGLPFKKHGYRDFVLRFGGKQSSTRRWFRFRWQWLNDLLIKIYV"
     CDS             6595..6999
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_10"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3e-24, bitscore:
                     75.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDTKIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             7125..8678
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_11"
                     /sec_met_domain="CT_Btheta (E-value: 2.8e-291, bitscore:
                     955.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETGEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             8699..9613
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_12"
                     /sec_met_domain="OAD_gamma (E-value: 1.8e-16, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             9639..10070
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 70; E-value:
                     3.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_13"
                     /sec_met_domain="Biotin_lipoyl (E-value: 8.6e-23, bitscore:
                     70.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKKGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             10073..11164
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg264_14"
                     /sec_met_domain="OAD_beta (E-value: 7.1e-143, bitscore:
                     465.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAM"
ORIGIN
        1 cactattact gcccctcctc cttggtgggt gttccagtga cgatcaatca gatgacaaca
       61 actctccgtt aatcggatct tggatatcca tagatgatga tgtcgagatt ttctatcttg
      121 acctcaaaaa agacgggaca gggaaatgga ccggaaccta cgccggagaa gtggaaaatg
      181 tactaaggct cacttggagt gcaaccgaaa ccacttacca tgtcaaatat gaaaacggca
      241 attctgaaac aaaacagtat agaatagaag gaaaccgcct ctatttagga gatgtgatat
      301 ataccagaaa gtaaagccag ccggggatca ctccccggct ttttcttcgt ccttcttttt
      361 tggatggaac acaaaatcaa ttaccttccg atttgcctta tcaatcctgc tccagtcctt
      421 tttaacataa gtgtctgtga cattataccc agacttatga ttcaatgacg ttgctacatc
      481 gtccatcgaa ataccgcagt cattccttgc tattgtagcc caagagtggc gcgcagcgta
      541 aagagttaga tcgggaatac ctaaagcatt cccgatcttt ttcagattaa gattcacctt
      601 atgcacaaat tgcttatggc tcgcatatct tataaagaaa ttaaacgctc tatcccctac
      661 tgaatcctta tatctttcca aataaggctc aagctccggt tctactttaa tggaaataaa
      721 agccctatca tcccgcctgg ttcttgtctt cctccgctcg tattcaaatc tatcatcaac
      781 agggggattc aaataaaaca tatcaacggt attcattcca accataaaga acgacatcag
      841 aaacacatct ctggcaataa tgacacccaa catattttcc ggtattcgat actcttttat
      901 agctcttatc tgttcatccg ttaaagaacg ctttcttgta attggttgct ttggaatttt
      961 gtatttagca aagggattat tggaaatgcg gattattccg gcatcttcat cgttatattc
     1021 aagctttgcc cgattaaata acgcttgtat cttcgacatg taaagccgaa ccccagaatc
     1081 agaaatattt ccaataccac attttgaccg ttgactcttt aaatcttctt caaatttaat
     1141 taagagagaa gatgtgatat ccgagaaaca taaatttcga tttcccacga atgcctcaaa
     1201 cttgctaata gcaattcgat aattttcccc tatccgccta ccttctttca aaaccttatc
     1261 cgcataagca taaccaaagt cgaaaaagtt aattccttca ggcttattag aaagtttatc
     1321 tttcatcagt tcacataatc ctttagcaga atacaaatca atagagtgac ccaattttga
     1381 aagttcggct ctaattttaa gaacatcgag cattacttgg tcataaatcg gattattcct
     1441 ttcttttagc tcaaaagtct tcttgtttat caactcactt cccacatagt gagtggtcgc
     1501 aatatatgaa gattgacgtt cgtgcgtaat ccgtatcttc acattccagg tattatcttc
     1561 tcgcctttga tgcttgagga tgattatttt aactgtagcc atcgttgtaa aacatttaat
     1621 cgtgcattcc tgtttttcgt aaaacgttcg taaaacaatt gcgcaaagat agcaaattaa
     1681 tttagatatg ctatctttgc gcaatacaaa gaggaacagt taattacagc taaaaaacta
     1741 tagcttaagt agttctctat acagtttttg caccggaagt cccattacat tgaagtagct
     1801 gccggatatg gattctactc cgacaaaacc gatccactcc tgcacaccat acgaaccggc
     1861 tttgtccatg ggctgatagt gatcgacata ataagcgatt tcatcttcat caagaatcgc
     1921 aaaacggaca tccgtcacgg cagcgaaaca tttttgccat tctcgggtag tgagacacac
     1981 accggtaatc acttggtgcg atttaccgga gaggctccac aacatctcta tggcatcttg
     2041 ccttccgaca ggtttgccga gcgctttgcc ttcatgccag acaatggtat cggctgtgat
     2101 caaaagctct tccggtccga tcatcgactg ataggcggct gccttctcac gggctatgaa
     2161 aagaggaatc tcttcacctt gcaacgtatc gggataagat tcgtccacat ccggcaaagt
     2221 ttttactaca taatcgacac ccaagcccgt catcagctct ttccgacgcg gagaattaga
     2281 ggccaatacg attttataac gatctaagtt agcaagcata ctgataaata aataaggtat
     2341 atactggaaa tcaccatccg aaagcatcat cggacaacca ttggccttgt gctttaagca
     2401 cctgctccac cacatcgcgt ccacagccgt atcctccatc ggcatatgaa atgtaacggg
     2461 caatcgcttt cacctcggga accgcatctt tgggacaaca aggcaatccg cactcacgca
     2521 tcacttccat atcgggaacg tcatcgccca tgtagagtat ctcctcgtcc gtaagtccgt
     2581 gtttgtcacg gaaaccacga taatcgtgta tcttcaccgc agagccgaag tacagatcgg
     2641 atacccccaa cccgataaaa cgtttccgca cgacatcgct ccgcccacct gtaataatag
     2701 cgatacgaag cccttttttt acggccaatt ggatggcata accgtctttt acatttaccg
     2761 tacgcatcgg ttcacccgac ggatgcaaag ggatgacatt ggcgctcagc actccgtcta
     2821 catcaaaaac aagtgctttt atccgggtaa ggtcgtaatt gattgtgctc atttttattt
     2881 aatgtttcgg gattattgtc tttcgtgaat gcttcggcta agcaactcgt ataaccgctg
     2941 catggcagga tcatcggcaa gcatccgcaa gtgattgccg atcacattct cgtcataacg
     3001 gatggccggc ccggtctggg ccgtcttagg ttccagttcg tgcaccttac gggcggtttc
     3061 atcaatcaac ggcaacatca cgtcaaacgg cagattgtat ttcttaagca actcggcagc
     3121 aagggcatac atgtgattgg tgaaattaca tgtaaacacg gcagccaagt ggagactttt
     3181 acgctgctcc gagtcggcat cgtacacacg gttggacagt gtagaggcaa tggctttcag
     3241 aaacgcggca tcttctgtcg aagaagcctc tatgaagaaa ggaatctcct taaaatctac
     3301 ctccctctgc ttgctgaaag tctgcatggg atagaacaca ccgtaatgcg ggacatgtcc
     3361 ttcccagaca ttcatcggga tgctacctgc cgtatgcacc atcaatgcct cttcccgctt
     3421 accttcgaca atgccctgaa gaagttcggc aaaggcggaa tctttcagtg aaacaatata
     3481 cagcttcgca tacgggttca cctctgcgag gtctgtcgta tattcggctt ccactttctg
     3541 tgccagctcg cgggccgact cttccgtacg gctatacacc tgtacgatac gaaaaccttt
     3601 ccgatataag gcttttgcca gattagtggc aagatttccg gcaccgataa atacgatcgg
     3661 cgtatcttct atacttcttt tcatcgtgtt gaaatcaaat acaatatacc tccgattatc
     3721 aataaagcca aaggcagcag ataaccggac atcgaaccaa gcaacgaaac aatcaggccg
     3781 atgttcagca ccaaccacaa tccgagcaat accaagccga cggatttatc ccgcttaata
     3841 aagaggaaaa tcaccgcagt gtaaagcaaa agattatcct tattcatcac ccagggtatc
     3901 cccaaagtgg aaaagtgtat cagtttgtcg atcagataga gcacccccat cacaataagg
     3961 gtgactgccg tggctttgta ggtatcttta ttgtttgctt ttaccgcact caccgttact
     4021 tacctccgaa cttattaata tggatttttt cccattgcaa atggtcttca ttaaagggtt
     4081 tacgttccat ccctttatgc ccgatcgcta tgacggacaa cacctgcaac tgcaaaggaa
     4141 tgtcgagcac accgcgcaca aattcatcgg aaggcatccc ggtggcagta tatcgctcac
     4201 gcacctgcac ccagcaactt cccaatccca agtcttcggc ctgaagctga atcataatag
     4261 aggcaatgga agcgtcctca atccatacat cgctcgccaa gggatcggca gtaacgacaa
     4321 tggccaatgc cgcgtcggca ataaaggccg aagcctgctc tttgcaatgt gaaagttcac
     4381 tgagcaactt tttatcatcg actgcaataa attgccagct gttactgcgc tttgaagtag
     4441 gagccatcag ggccgctttc agcaaagcga ctacatcttc ctgagaaagt tcttctccgg
     4501 taaatttccg catgctgcgg cgatttttta ttagttcact gaaattttcc atgtatctat
     4561 actttgcatt atttgaatat accgccagtc accatagaat gcacaaacac acgcgaaccg
     4621 aggtaccgcc cggcatgccc gtctatataa ggtatgccct gcaggacttt gcatgaatcg
     4681 gcgcgctccg tggcgattcg agcgcaaaga taggcaattt attccactct cgtcaactcg
     4741 ccggtcagtg aatcgatgat aaaaccatgc acccggacat ctttcggaat aagcggatgg
     4801 ttctctatgg aacgaaccgt gcccctgacg gacttcaccg gatcgtcgaa tccgcccagc
     4861 cacgaattaa aatcgacccc gcagtagcgt atcatgtcga ttgtttcgga cttgattccc
     4921 cgctttttca tgtgagctat catttcgtcg ctgttcatgt ggcaagcacc gcaatcagaa
     4981 tgggcaatga ccatcacttc ttctactccc aactcgatga tagccaccag cagactacgg
     5041 atgacactgc cgaaaggatg ggaaatgacg gcaccggcat tctttataat ctttacgtct
     5101 ccgttgtgaa tccccaaagc ggcgggcaac agttctgtca ggcgggtatc catacaggaa
     5161 aggatggcga ttttcttatc aggatacttg ttagtgatat acttttcgta tcccctgttc
     5221 tcaacgaact ttttgttgaa ttcaagaatt tcttctaaca taatcaaaaa cggattttat
     5281 tgtagtatct ccacaaagat agtcacaaaa cgacagctca acaaaataag ccctgcaaat
     5341 gttgtaaaga gaaataaaaa atgtaaattt gtcccgatat gccattaaaa ctgactacat
     5401 attaccaagg aagtgagatt ccggattttc ccggaaccaa tacgtttcat tcgaaagagc
     5461 tatttcagat ctacgaagaa actccgggct acaccccact cctgattatg gcttcggaag
     5521 acggaaaacc cgttgcgcga ctgcttgctg ccatccgcaa aagcatccgc atgtttcctc
     5581 ccgctttcat caaacgctgc gaaatctatg gcacgggcga atatctgata gcggaagccg
     5641 acaaggaaag gatattcagc gaaatgctgg agcacctcac cacggaggct ttgcggaact
     5701 cgtttctgat agaattccgc aatctggaga acgccatgtt cggctacaaa tatttccggt
     5761 ccaacagata cttccctgtc aactggctgc gggtacgaaa ctcgcttcac ggcatcgaaa
     5821 acgccgaaca gcgtttcagc ccctcccgta tccgccagat caaaaaaggc ctgaaaaacg
     5881 gagcaaaagt agacgaggca cgtacggtag aagagatacg cgaattttcg aatatgctga
     5941 ggcatctcta ttcgtcccgc atccgtaaac attttcccaa catcatcttt ttccaacaca
     6001 tggacacccg gctgattcac agccggcagg caaagatttt catcgtccgc tacaaagaca
     6061 aaattatcgg aggctctgcc tgtatctatt cgggaaacga tgcctatctc tggttttcgg
     6121 gaggtatgcg aaagacctat gccttgcaat acccgggtat actggctgta tggaaagccc
     6181 tccaggatgc ccatcaaaac ggattccgtc acatggagtt catggacgcc ggactcccat
     6241 ttaagaagca cggctatcgt gacttcgtgc tccgcttcgg tggcaagcaa agcagcaccc
     6301 ggcgatggtt ccgtttccgc tggcaatggc tgaacgacct gctgatcaaa atatacgtct
     6361 gaacatccgc ctgtctcagg gatcagcgcc aaccctctcc gccttttaaa ccacctccct
     6421 taggttttaa accaacgata cctgcctttt aaacccatgc accttaggtt ttaaacctat
     6481 tttcaccata attaattgca gaaaaatttc tttattaaac aagaattgat tttctttgtg
     6541 ctgttttata ccattccgaa aagacgatta ataccaaaat ttaaaaatat agttatgaag
     6601 atttcacaca ttgaacattt gggcattgcc gtaaaaagta tcgaagaagc ccttccgtat
     6661 tatgaaaacg ttttaggttt gaaatgctac aacatcgaaa ctgtagaaga tcaaaaagta
     6721 agaacagcct tcctgaaagt aggtgatacc aaaatcgaat tactggaacc cacatgtccg
     6781 gaaagtacca tcgcgaaatt cattgaaaac aaaggtgcag gtgttcatca cgtagcattc
     6841 gccattgaag acggcgtagc caatgccctg gccgaagccg aaagcaaaga gatccgcctg
     6901 atcgacaaag ctccgcgcaa aggtgccgaa ggcctgaaca ttgctttcct tcacccgaaa
     6961 tcaactctgg gcgtactgac agaactctgc gaacactaaa aagatgtacg attcggacga
     7021 tccgcgccac ggacaaacgg aatttttctt tgcattaaat tccccatccg ggttgtcaat
     7081 cgtcctgttg taaatattat aaccctttaa attaagaaaa actcatgagt aaccagcttg
     7141 aaaaagtaaa agagcttatt gaacttcgtg ctcaggctcg tttaggtggt ggcgaaaagg
     7201 ctattgaaaa acaacacgcc aaaggcaaat atacagcccg cgagcgtatt gcacagttgc
     7261 ttgacgaagg tagtttcgaa gaactggata tgtttgttca acacagatgt actaatttcg
     7321 gacaagagaa aaaacatttc ctcggcgacg gtgtggtaac cggttatgga acgatagaag
     7381 gtagattagt atatgttttc gcacaagatt tcacagtatt cggtggttca ctgtcggaaa
     7441 ccatggcaca aaagatctgt aaagtaatgg atatggccat gaagatgggt gcccctgtta
     7501 tcggtatcaa cgactcgggt ggcgcacgta ttcaggaagg catcaacgcc ctgtccggtt
     7561 atgctgaaat cttccagcgc aacatcatgg cttcgggtgt catcccacag atttcaggta
     7621 ttttcggtcc gtgtgccggc ggtgcggttt actctcccgc cctgacggac ttcacgctga
     7681 tgacggaagg tacatcttac atgttcctca ccggaccggc tgttgtgaaa acagtaacgg
     7741 gtgaagacgt gtctcaggaa gatctgggtg gtgcaagcgt acatgccagc aagtccggtg
     7801 taactcactt cactgccgaa accggtgaag aaggtctagc gattattcgc aagcttctca
     7861 gctttattcc gcaaaacaac ctggaagaag ctccattggt gaactgtacc gaccccatcg
     7921 accgtatgga cgacctgctg aacgagatca tccccgacag cccgaacaaa ccgtacgata
     7981 tgtacgaagt gatcggcgcc atcatcgata acggagaatt cctggaagta cagaaagact
     8041 atgcgaaaaa tcttattatc ggttttgccc gtatgaacgg acaatcggta ggtgtggttg
     8101 ccaatcagcc taaatacctc gccggagtac tcgacagcaa tgcttcacgc aaaggtgcac
     8161 gcttcgttcg cttctgcgac gcattcaaca ttccgctggt gacattggta gacgttccgg
     8221 gattccttcc gggtacgggt caggaatata atggtgtaat ccttcacgga gccaagttgc
     8281 tgtacgctta tggtgaagcc actgtgccca aggtaactgt taccctgcgt aaatcttacg
     8341 gtggttcgca catcgtaatg agttgcaagc aactccgcgg cgacatgaac tatgcatggc
     8401 cgacagccga aatcgccgta atgggcggtg ccggtgcagt agcggtattg tatgccaaag
     8461 aagccaaaga tcaggaaaac cctgctcaat tcctggcaga caaggaagcc gagtacacta
     8521 aactgttcgc caacccgtac aatgcagcca aatacggtta catcgacgat gttatcgaac
     8581 cgagaaacac tcgtttccgc gtgatccgcg ccctgcaaca gctgcagacc aaaaaattaa
     8641 ccaaccctgc taaaaagcac ggtaatattc cattgtaaca aattaaacat cgattgttat
     8701 gaataagaaa agaatcggga tatttatcgc tctgctggca atggtttgca tggggctcag
     8761 ggcgcaaagt gccaccagtc tgagaatcaa tgaggttttg gtcgtcaacg accagaacta
     8821 tcaggatgac tacggactgc acaatgcgtg gatagagata ttcaacacct ctttcgcttc
     8881 tgtaaatctg gaaggttgct ttctgacgaa cgataaaaac aatccgacca aatatcctat
     8941 tcccaaaggc gacgtgctga ctctgatcaa gccgcgccaa catgctttgt tctgggcaga
     9001 cggaatgcct aaccggggta cgttccacgt gaactttacg ctcgacccga acaaagagaa
     9061 ttacattgct ttgtatgact ctaacggtaa aactctgatt gacgaagtaa ccatacccgc
     9121 cggtcagctt gccgaccgtt catacgctcg cgaaaaagac ggaagtgcca actgggtagt
     9181 aaaaggtgaa ggagaacaca gctatgtcac tccgagcacc aacaatatga ctatcgacaa
     9241 aaacccgaag atcgagaact tcaagaaaca cgactctatc ggtatcggta tggccatcat
     9301 cgccatgtcg gtcgtattca taggtttggt actcttgtat ctttcattca aggcggtagg
     9361 taacgtagct gtcagactgg gtaagaaaaa cgcgatgaaa gccaccggta tcaccgacaa
     9421 gacggaagcg aaggaaaaga acctaggtag ccacacaggt gaagaaaccg ccgcgatcgc
     9481 catggctttg catgaatacc tgaatgacgc tcacgacgtt gaagacatga ttttgaccat
     9541 caacaaagtg aaacgcacct actccccctg gagttcgaag atctacacac tgcgtcagac
     9601 tccgaaaaga taattactaa ccctaataaa atgaagcaat gaaacaatat aaatataaaa
     9661 tcaacggcaa cctttacaac gttacagtga acgatgtaga agataacata gccaacgttg
     9721 aagtgaacgg aacctcttat aaagtagagt tggacaagcc cgtcaaagcc gctccgaaac
     9781 cggtgacccg tccggcagcc gctccgaaaa cggaaacagg tgctccggta gtaaccaaac
     9841 aaccgacagc ttccaaaaaa gacggtgtga aatctccgct tccgggcgtt atcctcgaca
     9901 taaaagtgaa agaaggggat accgtgaaga aaggccagac gatcatcatc cttgaggcta
     9961 tgaagatgga aaacaacatc aatgccaata aagacggaaa agtagcagaa attaaagtta
    10021 ataaaggaga ttctgtactt gaaggtacag acctcgtaat cattgaataa ttatgggaga
    10081 tttcgtatca ttcttaggga ataaccttgt tgacttctgg ggatacaccg gttttgcgaa
    10141 cgcgacaccc ggacatcttt tcatgttgct aatcggtctc ttctttatct accttgccgt
    10201 agccaaagaa tttgaaccga tgctgctgat ccccattggc ttcggtattc tgatcggtaa
    10261 tattccattc aatatggaag ccggattaaa agtgggtatt tacgaagaag gttcggtact
    10321 gaacatcctt tatcaaggag taacctccgg ctggtatccg ccgctcattt tcctgggtat
    10381 cggagccatg acggacttct cggcgctgat ctccaacccc aaattgatgc tgatcggagc
    10441 tgccgcgcaa ttcggtatct tcggcgcgta tatcattgcc ctgctcattg ggttcgaacc
    10501 caaccaggcg ggtgctatcg gtatcattgg cggtgccgac ggaccgacgg ccatcttcct
    10561 ttcgtccaaa ctggctccca acctgatggg tgccatcgct gtgtcagcct attcttacat
    10621 ggcactggtg ccggtgatac agccacctat catgcgtgcg ctaaccacca aacacgagcg
    10681 tctgatccgc atgaaaccac cgagaatcgt atcgcatacg gaaaaagtaa tcttccccat
    10741 cgtgggtctg ttgcttacat gcttcctggt tccttcgggt ctgcctttgc tgggtatgct
    10801 gttcttcggt aatcttctga aagaaagtgg agtaacccgt cgtttggcaa atacggccag
    10861 tggtccgttg atcgatgtga tcactatcct gttgggactg actgtgggag cttctaccca
    10921 agcttcacaa ttcctcacct gggattctat cttgatcttt atcctcggtg cattctcttt
    10981 catcatcgca acagcgtcag gtgtcatgtt tgtcaaattc ttcaatctat tcttgaagaa
    11041 aggcaataag atcaatccgc tgatcggtaa tgcaggtgta tccgccgtac ccgactcggc
    11101 acgtatttca caggtaatcg gtttggaata tgatccgacc aactatctgc tgatgcacgc
    11161 catggg
//
