LOCUS       c00033_gnlPro..        11054 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBHKHHEM_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:03:07
            Original ID  :: gnl|Prokka|DBHKHHEM_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11054
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11054
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[68:4679]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      69..4679
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11054
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11054
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             69..485
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.5e-26, bitscore:
                     82.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVAGALAEVEEKGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             542..2095
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_2"
                     /sec_met_domain="CT_Btheta (E-value: 9.4e-292, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             2127..3059
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_3"
                     /sec_met_domain="OAD_gamma (E-value: 7.6e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             3083..3517
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.9e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             3519..4679
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_5"
                     /sec_met_domain="OAD_beta (E-value: 3.5e-153, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             4849..6201
                     /locus_tag="ctg33_6"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALILIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAISITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDVSKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             6312..8162
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_7"
                     /sec_met_domain="Alpha-amylase (E-value: 1.6e-64, bitscore:
                     207.8, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRKDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKDSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(8633..9643)
                     /locus_tag="ctg33_8"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(9926..10933)
                     /locus_tag="ctg33_9"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
ORIGIN
        1 aaatgtcttt ctttgtgctg ttttatgcca tataagcaca taattaaacc atataaaaaa
       61 atatagttat gaagatttca cacattgagc atctgggcat tgccgttaag agcattgaag
      121 aagcccttcc gtactacgaa aacgttttag gtttgaaatg ctacaacatc gaaaccgtgg
      181 aagatcagaa agttagaacc gctttcctga aagtgggcga tgtaaagatc gaattgttgg
      241 aacctacttc tcccgaaagc acaattgcca agttcatcga aaagaacaac ggtaacggtg
      301 gcatgcatca tctcgcattc gccgttgaag acggagtggc cggtgcgctt gccgaagtcg
      361 aagaaaaagg tatccgcctt atagacaaag ctccccgcaa aggtgcagaa ggtctgaaca
      421 ttgcattcct gcatccgaag tcaaccctcg gcgttctgac tgaactttgc gaaaaaccgg
      481 aataagcacg accataaatc gtccaaccat aaattgtata aacattaaag aatataaatt
      541 catgagtaat caacttgaaa agattaaaga gcttatagac cgccgcgctg cagcacgtct
      601 cggtggtggt gaaaaagcga ttgcaaagca acacgagaag ggtaaatata cagctcgcga
      661 gcgcatagcc atgcttctcg acgaaggcag tttcgaagaa atggacatgt tcgtagaaca
      721 tagatgcacc aacttcggca tggaaaagaa acactacccc ggtgacggtg tagtaaccgg
      781 ttgcggtaca atcgaaggcc gtctggttta tatcttcgca caggacttca cagtttctgc
      841 cggttcactg tccgaaacca tgtctctgaa aatctgtaag attatggacc aagccatgaa
      901 aatgggtgct ccgtgtatcg gtatcaacga ctcgggcggt gcacgtattc aggaaggtat
      961 caatgccttg gctggctacg ctgaaatctt ccaacgtaac atccttgctt ccggtgtcat
     1021 cccgcagatt tccggtattt tcggtccttg tgccggtggt gccgtttact ctcctgcatt
     1081 gactgacttt acgctgatga tggaaggtac atcctacatg ttccttaccg gtccgaaggt
     1141 agtaaagact gtaaccggag aagacgtaag ccaggaaaac ctgggtggcg cgagcgttca
     1201 ctccaccaaa tcaggtgtta ctcatttcac tgcacagact gaagaagaag gcttggctct
     1261 tatccgcaaa ctgttgagct acattccaca gaacaatctg gaagaagctc cttatgtaga
     1321 ctgcacagac cctatcgacc gtctggaaga ttccctgaac gacatcattc ctgataaccc
     1381 gaacaaaccg tacgatatgt acgaggtaat tggcgctatc atagataatg gtgagttcct
     1441 cgaaatccaa aaagattatt caaagaatat cattatcggt ttcgcacgtt tcaacggaca
     1501 gtccgtaggt atcgttgcca accagccgaa gtatctggca ggtgtgctcg acagcaacgc
     1561 atcccgcaag ggcgcacgct tcgtccgttt ctgcgacgcc ttcaatattc ctatcgtatc
     1621 attggtagac gtaccgggat tccttccggg aaccggccag gagtacaacg gcgtcatcct
     1681 gcacggtgcc aaactgctgt atgcatacgg tgaagctact gtacccaagg ttaccatcac
     1741 actgcgtaaa tcctacggtg gttcgcacat cgtgatgagc tgtaagcagc tgcgtggcga
     1801 catgaattat gcttggccta ctgctgaaat cgctgtaatg ggtggtgcag gtgccgtaga
     1861 agtattatat gcccgcgaag ccaaagagca ggaaaatccg gctcaattcc tggctgaaaa
     1921 agaggctgaa tacaccaagt tgtttgccaa tccttataat gcagctaaat atggctacat
     1981 tgatgatgtt atcgaaccgc gtaacacacg tttccgcatc attcgtgccc tgcaacagtt
     2041 gcaaaccaag aaattgacta acccggctaa gaagcatggt aatattccct tgtaatcaag
     2101 cttttcacac taaaacaaga acgattatga ataaaacaaa aatcggaata ttcctttcat
     2161 tgatgctggt gttaggcttt tgctcttctt gcaaagaaca gaaatcgaac aacaaactgc
     2221 tgctgaatga agtgctggtc aacaacgaaa gcaactatca ggatgactac ggtgtgcaca
     2281 gcgcatggat tgaaatattc aacagatcat acggcagcgc cgaccttgca ggttgctatc
     2341 tgaaattcag cagccagccg ggtgatactg ccagttattt cattcccaaa ggtgacgttc
     2401 tgacactcat aaaaccacgt cagcatgcac ttttctgggc tgatggagaa ccaagacgcg
     2461 gtacatttca tacgaacttc aaactggatg ccacaaatgc caactggatt gggttgtatg
     2521 attccggcaa gaaattgctt gatcaagtca tagtgcctgc cggtacttta aaagccaacc
     2581 aatcctatgc ccgtgtcagt gatgcagccg accaatggga agtaaagggt ggaagcgaag
     2641 ataaatatgt cactccgagt accaacaaca agactatcga cagcaatgcc aaaatggaaa
     2701 aattcgaaga gcatgacagc gtaggtatcg gtatggctat ttctgccatg agcgttgtat
     2761 tctgcgggct gatattactc tacatctcct tcaagattat aggtaaaata tcagttaacc
     2821 tcagcaaacg caatgctatg aaagctaaag gtattactga taaacaagaa gcaaaagaga
     2881 aacaactggg gcaggctccg ggagaagttt ttgctgccat ttcaatggcc atgcacgaat
     2941 tccaaagcga tgtacacgat gtggaagaca cgatacttac cattacccgt gtaaaacgca
     3001 gttactcacc gtggagttca aagatttata cgttgcgtga gactcctcac aaaaagtaag
     3061 tcacccataa taaaataaaa cgatgaaaga atataaatat aaaattaacg gtaacgtata
     3121 taaagttgcc attggagata ttgaagacaa catcgctcac gtagaagtga acggtactcc
     3181 ctacaaagtt gaaatggaaa aagcaccgaa ggtagtcgtt aaaccggtag cacgtccggc
     3241 agccacatcc gctcctgctg ctcctgctac tccggtagta aaaccggccg ctgcttctac
     3301 cggcaagtca ggtgtaaaat ctccgcttcc cggtgtaatc ctcgatatca aagtaaatgt
     3361 cggcgataca gtaaagaagg gacaagttat catcattttg gaagccatga agatggaaaa
     3421 caatatcaat gctgataaag acggtaagat tacagccatc aatgtaaaca aaggggactc
     3481 tgttctcgaa ggtactgacc tcgtaattat tgaataatat gggagaattt atcacatttt
     3541 taggaaacaa ccttgccgac ttctggactt atacaggttt tgccaatgca acggtaggac
     3601 atgtggtaat gcttctggta ggtttgtttt tcatatactt ggctgtagcc aaggaatttg
     3661 agccgatgct attaattcct atcggtttcg gtatgctgat tggtaatata cctttcaata
     3721 tggaagccgg attgaaagtt ggtatctatg aagaaggttc cgtacttaat attctgtacc
     3781 agggagtaac ctccggttgg tacccgccac tcatattcct gggtatcggt gccatgacgg
     3841 atttctctgc tttgatatcg aaccccaaat taatgttggt tggtgcagca gcccaattcg
     3901 gtatattcgg tgcttatatg attgcccttg ccataggatt tgacccgatg caggctggtg
     3961 caatcggtat cattggtggt gccgatggtc cgactgccat cttcctctct tccaaactgg
     4021 ctcctaactt aatgggtgcc attgcggtat cagcctattc atatatggca ttagtaccgg
     4081 tgatacagcc gcctattatg cgttggctga ccagtaaaaa tgaacgtctt atccgtatga
     4141 aacctccccg tgtggtttca catacggaaa aagtaatgtt cccgattatc ggtttgttac
     4201 taaccacatt ccttgtacca tccggtctgc ctttgctggg tatgctgttc ttcggtaatt
     4261 tactgaaaga aagtggagtt acacgtcgtc tggcaaacac agccagtggt ccgctgattg
     4321 ataccattac tattctgctt ggtttgacag taggtgcttc tacgcaagca tccgagttct
     4381 taacccttga ttcaatcaag atattcggtc tgggcgcctt atcatttgtc attgccacag
     4441 catccggtgt catcttcgtg aagattttca acctcttcct gaagaaaggc aacaagatta
     4501 atccgttgat cggtaatgcc ggtgtatctg ccgtacccga ctctgcacgt atctcccaag
     4561 tagtaggtct ggaatacgat cctaccaact atctgctgat gcatgccatg ggcccgaacg
     4621 ttgccggtgt aatcggttcc gctgtagcag caggtatcct gctgggattc ttaatgtaat
     4681 acatttattc attccgttat ccggcttgaa ttccgaacta ttttagagcc ccttcatttt
     4741 tggaggggct ttttcgttaa tctatctaaa acagattacg attatttcgt aaatatattc
     4801 tttttagtaa cttgcagtca gtttaacctc atataaatga tatactgtat gcgaaagctt
     4861 tttatctcct tatgtttcag tgcatgctgt tcgcttctgg cggcacagac cacaaatccc
     4921 attcaagagg cgatggccaa ctacgattat gaaacagcct tgatactaat cgatcaagaa
     4981 accccgaccg tccccctact ctaccaaaaa gggaaagcgc tgaaagggct gggcaataac
     5041 cttgaagctc tgagcgtatt tcaggaagtc gtagctcagg attctctcaa tccccgagca
     5101 tacattgaag ctgccgaatg ctgcaaatca ctcgccaaat atagtgaggc gctggattac
     5161 taccagaatg cgctccacat aaatccggac aataaatacg cacgcatcca gtatatcagt
     5221 ctgctgatga acatgaagag ataccgtgag tctctaaagg aaagcaacct gctggcagaa
     5281 agggacagtt ccgcctatgt actacacctt agagccgaaa gtatggggca agtctatgac
     5341 aacacagaaa tcatgcatgt gatagatgcc tacctggaca tacagaaaag gtatcccaat
     5401 gattacctgt ctgctgccaa actcggcaac atctatgtag caggccacca gtatgaagac
     5461 gccataagca taacggagaa ataccgttcc atagactcca ccaacgtcct tgtgaaccgc
     5521 atcaatgccc aagcctattg cctgaacaaa gattacccca aagcaataga aagatatgaa
     5581 caactgttac aggaaaaaga cagttctttc caaacctgct tctacgccgg aatcagctat
     5641 tatgccctcg aagacttcta cccagcacac gacctgctgg aaagggctct taaagatgac
     5701 aataccaaca tcaacgttct ctattatctg ggacgcgcct gctccaagac atcatggaaa
     5761 gaggatggag tgacttatct ggaaactgcc gtaagcctcg ccatgcccag cgacagtgtc
     5821 atgtcccgcc tatatgtggg gcttgcggac tgctacaaga tggcatttca atacaccgac
     5881 caggcgaata cccttctgac gcaatacgaa aaatacgacc ggcagaaaca caaactgctc
     5941 tacgacgcag cctttatcta ttattactat ctgaaagatg tgtccaaagc agagagatat
     6001 ctgacggcat acctgaaaac ccgtccgaaa aacagcaagg acaaagtgca ggaagtagat
     6061 gcggacggag ttcccatcat cggagaagac aaccgataca atgccgccga aaactggctg
     6121 aaggacatca gagaaaagcg caagaaagag gacttcttca agggaaaggt cgataccgcc
     6181 agcgtaaccc ccatcaaata gccccaatga aaacgtttgc ataatataat aaggtacagt
     6241 aacggagaaa gattaacttt ctccgttatt tgttttaaat tagcgcaaaa attaaccgta
     6301 aagttactat catgaaaaaa gtattcttaa tcttgggaac actcttactc tccctcagta
     6361 cgtatgcagc tatgaatgtg aacaaaatcg accctccgtt ttggtacacc ggcatgcaga
     6421 acccggaact ccagctgatg gtctatggcg aaggcatcgg caacgcggca gtatccgtca
     6481 attatcccgg cgtctcattg agcagcaccg tcaagctgga aagcaacaac tacctcctgg
     6541 tctatctgaa actggacaag gatgtaaaac ccggcaaatt caacctcacc ttcactgaag
     6601 gaaaaaagaa actcgtaaag gaatatgaac tgaaggcacg caacaagaaa ggttgcgaac
     6661 ataaaggttt cgacgcctcc gacgcactgt acctgctgat gcccgaccgc tttgccaatg
     6721 gcaacccgga caatgaccag attgcgggca tggccgagta caagatagac cgcaaagacc
     6781 ccaatgcacg ccacggcggt gaccttgccg gcatcgaaca acacctggac tacttctccg
     6841 acctcggcgt cacagccctc tggtttactc cggtactgga aaacaacatg accggcggtt
     6901 cctatcacgg ctatgccacc acagactact acaaggtaga cccgcgcttc ggtaccaacg
     6961 aagaatacaa gcaactgatt gaaaaagccc atgcacgcgg catcaaaatc gtaatggaca
     7021 tgattttcaa ccactgcggc gtagagcatg tatggattaa ggacatgccc tccaaagact
     7081 ggttcaacaa ccccgaccac gaaaacaact tcgtgcagac ctccttcaaa ctgaccccgc
     7141 acgtagaccc ttatacttcc cagtacgatg ccgaccagat gaacgacggc tggttcgtac
     7201 cttccatgcc cgacctcaac cagaagaacc ctcacgttta ccgctacctg gtacagaaca
     7261 gtttctggtg gattgaattc gccaacatcg acggcatccg catggacact tacccgtatg
     7321 ccgactatga tgccatgagc aactggatga aagagctcaa cgaagaatat cccaactaca
     7381 acaccgtggg cgagacctgg gttaccgaac ccgcctacac cgcctggtgg cagaaggatt
     7441 ccaagctatc agcccccaag aacagtaacc tcaagaccgt tatggacttc agcttctttg
     7501 acaagataaa caccgccaag aatgaacaga ccgaaacttg gttcaaggga ctggaccgca
     7561 tatacaataa cttcgtatac gacttcctct accccaaccc cgcttccgta ctggcattca
     7621 tcgaaaacca cgacaccgac cgcttcctgg gcgaaggcaa caaccttccg atgctgaagc
     7681 aagcctctac cctgctgctt accacccgcc gcattccgca actctactac ggaacggaag
     7741 tcatgatgaa tggcgtgaag agcaagagcg acggctatgt ccgcaaggac ttccccggcg
     7801 gatggaccgg tgacgcaaca aacgcactga ccccagccgg acgtaccaaa atacagaacg
     7861 agtgctacga cttctacaag accatcctaa actggcgcaa aggaaacgat gtgattgcca
     7921 aaggcagcat ggtgcagttc atggtacaga atggtgttta tgcctacgca cgccagtacg
     7981 aaggcaagac gatattcgtg atgctgaacg gtacagatgc agagaccacc gttcctttga
     8041 aattctacaa ggaaatccta aaagacagca agcagggaaa agatattctt agcggcaagg
     8101 ccatcacctt cggtgaagag ctgaagatgg gccccagaga atcattagtg atagaattat
     8161 aacgcgcact ccacacagag agctcattct tgcaaatctc ccttgcagat agcttgcaga
     8221 cacctcgcct gccagccatc tgcaagggat ttttagtatg gaataggtgt cacggggata
     8281 tgcttttcac cggtctcaaa tatagctaat ctgttagttc ataacggtga acactttgtt
     8341 ccagtataga gaaacaaagt gttcggatat gtagaaacaa agtgttctta cgtattggaa
     8401 cgaagtgttt ttgcatattg gaacgaagtg ttctctttat tgaaacaaac tgttcagtta
     8461 agggaaacag actgttttgt taaaggaaac agactgttgt acacgttgaa acatccgctt
     8521 ctgaaataac cggcgaactt aaccatccca caacaccggc ctatatataa caagtcagcc
     8581 cttgcaacat caatattgca agggctgacg ctatattcgg attatctttc gattagtcca
     8641 gttgagccaa tttgttctct gaaccaagca cgttgatgat tttatgcttg tacagttttt
     8701 ccatattgtc acgagccgga cccagatact tacgcgggtc gaattctgcc ggtttttcag
     8761 caaatgtctt gcggatagca gctgtcatag ccagacgtga gtcagagtcg atgttgattt
     8821 tgcaaacagc agacttggca gccttacgca actgctcttc ggggataccg atagcagctt
     8881 ccagcttacc accatacttg ttgatagtat caacttcttc ctgaggaact gaagaagaac
     8941 cgtgaagaac gatggggaat cccggaagtt tctccattac agcatccaga acggcaaatt
     9001 ccaaaggagg aggaaccaga cgaccggtag cagggtcaac gtggcattgt tcgggtttga
     9061 acttgtatgc accatgagaa gtaccgattg agatagccag tgaatcgcaa cctgtacggg
     9121 tagcgaagtc aataacttct tcaggattag tatatgtatg gtgttctgca gaaacttcat
     9181 cttctacacc ggccaataca ccgagttcgc cttctacagt tacgtcgaac tgatgggcat
     9241 agtcaactac cttcttagtc agtgcaacgt tttcttcgta cggaaggtgt gaaccgtcaa
     9301 tcattactga agagaaaccg gagtcgatac agctcttgca agtttcgaat gtatctccgt
     9361 ggtcaaggtg aagaacaatt tcaggatgtt tgcaacccaa ttccttagcg tactcaacag
     9421 caccctgagc catgtaacgc aacagcgtag cgttggcata ctgacgggca cccttagata
     9481 cctgaagaat aaccggagac tttgtttcaa ctgcagcctt gatgatagcc tgcatctgtt
     9541 ccatattgtt gaagttgaat gccggaatag catatccacc tttgatagcc ttagcaaaca
     9601 tctctcttgt gtttaccagt cctaaatctt tgtaattaac cattttgttt aaattttatt
     9661 gttagtgaat taaaattcta cgcaaaagta atcattatcc tttaaagtaa agaacttgag
     9721 aggaataaaa tatccggctc atcctaccaa atccattcta ttttaaagct attggcttca
     9781 tttaacagat tattgtaatc tctatattac aaactctttg catttatctc tgccagccat
     9841 acttttgcca tctatacttc tatcaacaaa aaagccggag aacatgtttg ctctccggca
     9901 tctgtttaca cattattatg taatactaat ttttcagata gatgatggtc ggcaaatggt
     9961 cactgtaacc gttcagccaa gtcctgcccc catgcgtacg caagggggaa cctttgtatt
    10021 tgccatcctg ctgaatcaga taatcgcgga tgaaaacttc attgtgatca tagcgcaacc
    10081 ctttcttagc cttcagcaac ggtttcgaaa tgacaatctg gtcaaacaag ttccacttgc
    10141 cccgatagag caatgtcccc actcccttgt cttccagtgt ctcccaccag ggattgtaga
    10201 attcgccttt cttcacctgc ttcggatatt tgcgtgcacc cagcacctcc atgctttcat
    10261 ccatcgggtc gtcattcata tcccccatca cgatgagctt cagcttcttg tcgctacgca
    10321 tcagagagtc cttcaaggcc tttacctgcc tggctgcatg cacacgcacc ggtgactttg
    10381 ccccacggga gggccagtgg ttcactatca cgcagacacg ctctcccgcc agttgtccgt
    10441 ccacaatcag gaagccgcgc gtcaagtgca ccgtatcccc ctcaaaagga gtagaaagca
    10501 ccaactttga gtgggtaacg ctgaactgct tcgggtcgta cagcaaggca cagtctatac
    10561 cccgtctgtc cggtccttca taatgcacga actcataatt ggaaatggcc ggctgcttca
    10621 cgaggtcttc cagcacccgg ctgttctccg cctctgccac accgatgaat gccggacctt
    10681 ccggcactaa atcacgcgaa agggaaccca acactttgga aaggttctgc agcttggact
    10741 catacttctt tgccgtccat tggtaactgc cgtcgggcag gaactcatag tcattcttac
    10801 ctgcatcatg aatcgtatca aacaagttct caagattgta gaacgcaaca ctatacagtt
    10861 tccgttccgc attttgtgcc cccagcgttg ccacgcacag ccagaaagag cataagacaa
    10921 gtagtttcct cataaattca caagattaag tcctgcaaaa atcagaaata aaatgcgata
    10981 aacctactaa ataaaaataa atctgaattt attttgtaga gtctccaact tgcactatct
    11041 ttgcgctctg aaaa
//
