LOCUS       c00218_gnlPro..        14703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBHKHHEM_218.
ACCESSION   c00218_gnlPro..
VERSION     c00218_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:03:07
            Original ID  :: gnl|Prokka|DBHKHHEM_218
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14703
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14703
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[140:4703]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      141..4703
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(141..707)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-70, bitscore:
                     227.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILPEEYGML
                     VFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(742..1377)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_2"
                     /sec_met_domain="FMN_bind (E-value: 2.5e-24, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPAAVDTLSAK"
     CDS             complement(1404..2396)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.4e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(2403..3740)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_4"
                     /sec_met_domain="Fer4_10 (E-value: 2.2e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.5e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.3e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.4e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(3801..4703)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_5"
                     /sec_met_domain="Fer4_7 (E-value: 7.3e-13, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-09, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.8e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.3e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.4e-06, bitscore: 16.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDTA
                     PQVKVAVPKAEVETPKAEV"
     CDS             complement(4741..5160)
                     /locus_tag="ctg218_6"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADANAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLIPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(5391..6791)
                     /locus_tag="ctg218_7"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLEEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(6863..7069)
                     /locus_tag="ctg218_8"
                     /transl_table=11
                     /translation="MPRAYTACRSGCALLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             7101..8720
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg218_9"
                     /sec_met_domain="GATase (E-value: 8.3e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKEAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             8752..10605
                     /locus_tag="ctg218_10"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYSMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKIAGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDAKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPIMFLFILNDYPSGLNYYYFISTLISVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKERQNKK"
     CDS             10708..12039
                     /locus_tag="ctg218_11"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMAAVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCRKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFAVFPKLILG
                     IYTDIPDLQDASVHSLWAMCSTYLFLVPANVYFQAVSGTGNTRTAWGLEMATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             12101..14200
                     /locus_tag="ctg218_12"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAAALIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSGNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSQSIYFIGVWHGETQIYNIDLAGNDKLTQLTDGMYDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRTFFEWLDKW
                     LKPAK"
ORIGIN
        1 atgttgttta caaagattgc cgagataaat atcaatatat attccataat cattaaatta
       61 agaattaaaa actaaaaatt aaaagcccgg cagcctaccg ccgatacgtt ctcaattttt
      121 tcatttttaa tttttcatta ttaattcttc ttcatactgt tgattaaagc aatgagatag
      181 cccaatgcga tgaatgcacc cggagcaagg acaaatacca acatgccgta ttcttcagga
      241 aggatactca agttgaatat cttgccggtt cccaggaact cacgcacggc acccagtaat
      301 gtcagtgcaa tggtaaagcc caagcccatg cccagaccgt cgaacaagga agccaccgga
      361 ttgtttttgg cagcaaatgc ctcggcacgt cccaatacga tacagtttac aacaatcagc
      421 ggaatgaaca ggcccagtgt ggcgtacaat gcaggaacgt aagcttgcat tatcatctgc
      481 aacagtgtca caaatgatgc tatgactaca atgaatgaag ggatacgcac catatcggga
      541 atcagattct tgatggcaga aatcaccaca ttggaacata tcagcacgaa cattgtagcc
      601 agtcccatac ccataccgtt aatggcagag gaagtggtac ccagtgtagg acacataccc
      661 agcaggagca caaacgtagg attctctttg ataatcccgt tcatcataac tttaaaatta
      721 ttcatatctt ctactccttt cttatttagc gctgagtgta tccacagctg cgggagctgc
      781 ggaatcagca ggttgttcaa cattcttttg agtagcgccg gtagtgccgt cggcagtttc
      841 ctgaccggca taggcagcat aagccgcatt cactgcattc aaaaaagcac gtgaggtgat
      901 ggtagacgct gtaatggcat ctactttacc accgtccttg ctcactgtca atgcagcttc
      961 acccggattc atgccggtga tgtcaccttt attgcctttc ttgaaccagt cggcagcctt
     1021 ggaacccaac cccggagttt ccacatgcga caacaaggag tagtcgatga ttttgccttc
     1081 agcatcgaaa ccgaccaaca ctttcagctc accgccaaaa cccatggcaa cagcttccac
     1141 agcagctccg atatattctc cacctttggt ggcaggatat acagaatact gtactccgtt
     1201 tacttcctgc atcttcttct cggcaatggg gtcattgtcg aagcccggaa ccaccgcact
     1261 tacggcatcg ctcaaggtct ttgcattggc ctgcgcaatg ggctccttcg tcaattcgtt
     1321 tacataagcc agcaacgcta cggagattgc ggtaacgccc gtaagtacca gcaacatatt
     1381 cttcaaggat gattctaact ttttcatttc ttcttcgcta cctccccaaa gcgtttaggt
     1441 ttaacatagg tgttgatgag cggagtgaac gcattcataa tcagaatggc aaacgacata
     1501 ccctccggat atgcaccgaa cagacggatg atgacagtca gtaggccgat gcaaacacca
     1561 taaatcagca tacctttgtg gctcatcgga gaagtcacgt agtccgtagc cataaagaca
     1621 gcacccagca tcagaccacc ggacaacaac tgtacgaccg gggatacata aagttccgga
     1681 ttgaccagat acatgatacc ggagaacacg aataccgtca ccagaataga taccggaatg
     1741 tgccaggtga tgattttctt ccacaacatg tagaacaaac caagcagcag cgccaaagca
     1801 ctcacctcac cgagacatcc tccattatta cctatcagaa ggtcgaaagc tcccggaagg
     1861 tcgctcaggg acatgcccgg agcaccattg atgacacctt tcataatagc cagcggcgta
     1921 gcagccgtcg tggcatccgt ataggctgtc aactggccta cagccggcca tgtcgtcatc
     1981 tgcacgggga atgaaagcaa caggaacaca cgtcctgcca gtgcagggtt aaagggattg
     2041 caacccaaac ctccgaagga catcttgcct accccgatgg caaacaaggc accaaggatg
     2101 ataatccaga tgggcaggtt ggaaggcagg ttaaaggcca gcaacacacc ggtaatgatg
     2161 gcagagccgt cggtgatggt tgtggtctct tttttcatga ggaatttgcc gatggcccat
     2221 tcaaagaaca agcaggctgc tacggaagtt gccgtaacaa tcagcgcacc cagtccgaaa
     2281 aagtaaagcg aaacgaggaa tgccggaatc aatgcgataa gcacaccgta catattcttc
     2341 ttcacgctgt caccgccgtg aacgtggggc gaaagggata cgattaattt attcatactt
     2401 cgttattttt tagcttgacg tgcacggatc atcgctccta ccttaccctt acccaagcgg
     2461 atataatcca gcatcggacg gttggaagga caagtgaact ggcatgaacc gcattctata
     2521 cacgacataa tgtcttcttt ctctactctt tcaaaatctc cgtgggccga aacggtagcc
     2581 agcagatacg gctccaaccc catcgggcag gctcccacgc acttggcaca acggatacaa
     2641 ggctgtactt cgccgcgctt ggcttccttc tcgttcataa tcagaatacc ggagcttcct
     2701 ttggctgtcg gtacatccgt atttaccaga gctttaccca tcatcgggcc accgccgata
     2761 atcttacccg tatcttcggg cagaccgccg caagcttcaa tcagctgctt catcggcgta
     2821 ccgatacgtg ccaggaaatt ggacggcttt gccaacgact taccggtcac ggtaatgaca
     2881 cgctcaaaca gaggtttgtt cttctgtacg gcctggtaaa cggcaaatgc ggtacccaca
     2941 ttctgcacca cagctcccgt ggagataggc aacgcaccgg ctgcaacctg gcgactgatg
     3001 acagcatcaa tcaactgctt ttcaccaccc tgcggatatt gtaccttcaa gggtaccacc
     3061 tcgatacctg catagctgga agcaaccttc gtcatcagct ggatggcatc gggcttgttg
     3121 ttctcaatgc cgatgaatgc cttgttcacc tttaccgcct tcatcagaat ggatacacct
     3181 accataattt cttccgcatg ttccagcatc agctgatggt cggcagtcag atacggttcg
     3241 cactctacgg cgttgatgat gacacactct gccttgaatg caggaggagg acacaacttg
     3301 acctgcgtag ggaagcatgc accgcccaga cctacgatac cggcatcagc gattttcttc
     3361 acgatttcct cggaggtcag actgcattcc ttcaccaacg tttcggaacg gtcaatggat
     3421 tcttcccatt catccccttc tacgtcaatg aatatagcag gcttggcgta accgctggca
     3481 tcgacaatcg tgtcaatctt agcgactttc ccgctgacag acgaatgaat ggctgctgat
     3541 acaaaaccgc cgggctcggc aatctttgta cccactttca caacatcacc tttggcaacg
     3601 ataggcttgg caggagcacc gatgtgctgt cccagcaaga tagcggcctt ggccggaatc
     3661 tctgccttga tgataggctg atgtgctgaa agtttatttt cgtgtggatg gactccacca
     3721 attgaaaatg tcttcaacat acaattctgt atttttagtc gtttatttac tttattaatt
     3781 catacctcaa cttgggaagt ctaaacctct gctttaggag tctcaacctc agctttagga
     3841 actgcaacct ttacttgggg agctgtatcg tcagccttcg gtttgcgcgg cgggaagttg
     3901 agggcaatga ttgtgttttg cggacaagct tcctcgcact tgcgacagga tttacactta
     3961 ttggggtcaa tgtaagccag attgttttcc agcgtgatag cctcgaacgg acaaaccttc
     4021 acacacttgc cgcaaccgat acatgccacg gtacaagcct tgcgtgctac ggcccccttg
     4081 tccttgttta cacactgtac gtaaatacga cgtgatttct tgccttgagg acggatttca
     4141 ataatagatt tcggacaagc cttggcacaa gctccacaag ccgtacactt ttcctcatcc
     4201 acttcgggaa gtccggtctc cggattcatg tggatagcat cgaactggca ggcagccaca
     4261 cagtcgccgc atcccagaca gccataacta caacccgttt caccaccata gagagaagcc
     4321 gcaatggcac aactcttggc gccatcgtat tggttcacac gaggacggtt ggcacaagtt
     4381 ccattacatc tcaccaccgc aaccataggt tcggcagcag cggcatccaa gcccagaatc
     4441 tcggcaatct ttgtcatgac gggctgtcca cccaccggac aaagtttacc atccagcgaa
     4501 cctgccttta cgcaagcatc tgcaaatccg ctacaaccgg ggtaaccaca tccaccgcaa
     4561 tttgcctggg gaagcacctc tgctacctgg gcaatccgcg gatcttcata cacggcgaat
     4621 ttcttggaag ccacgtaaag aatagcggcc gataccagcg ctataactcc caatgaaatc
     4681 actgcaatca gaattacatt cataaattag ttgtttatta attatttgtt ttattattag
     4741 ttagttcatc ggtcgtacgg agaatgagaa cttcttaccc atccgcgact tgttcagcca
     4801 caatatataa taataaggta taagaagtgc cagcgaacaa agtgcagaac gcagctcgtc
     4861 attccagata gccataaaga caaacagtga gattatcaga ataaggaaag gaaatataaa
     4921 ggcaaacaga actgccatca ctcccattga aagttcgccc gtcacccata cacggtcacc
     4981 gggctggtag gatgcggcat tggcatcggc cacatcgaca agtttctctt tcgtatccgc
     5041 agaggtacaa tgccccttga cactacacga agcgcacgct gaagtctgga tgattctcac
     5101 ttggagatga gaaccgttta tgttttccac aataccttga tgttttatag tattcgccat
     5161 tttgcaaagt gtgcattaca aatcgcggca aatttacgca ttatttgtga actgcaaacc
     5221 tttcctatgc attttctgtg ttcgtaaacg tgctttttct atgtttttat gttttttcac
     5281 ctgccacaga ctacaaaaag acaaaaaaca gacggtctgt caaggaaaaa cagaccgtct
     5341 gactaaccaa aacagataat ctgttcactc cgaacagacc atttgtttat ttaccattta
     5401 taattgatac cgaaactgag caattctttt acctgaaaat agctgtcccc ttccgtcggc
     5461 ttggcactgt cgtcatagcg ggcgtgcaca tagagcttgg tggaaagata gcggttcagc
     5521 acaaagttca ccgtgttttc ccattcgata cgcgtccact cataactggt ctggaagtcc
     5581 aggcgggaat ccagcgtaat ggaaggaatg atggtccacg aaagtgtagg ctgtatctgc
     5641 gaaccgaagt tatgcttcac gcacttgccc tcctcaagac cgaaactcac ttcattcaca
     5701 cccttattcc ccacatagcg cagcatgtac gtcagcggag ccatgaaaac ggacaagctg
     5761 aatttctgct tcttcaactt gtagtccata ccgatactgc ttgaccagtc cgccggagca
     5821 aagaaagccg aaaccagctc ttcactgttg gccttgtagc cattgcagaa ctgggtctta
     5881 aactcagtcg tgatggtata ataccacttg gacgcagcct gaatacccag tttactgtac
     5941 agccggagtt ggtcggtact taccagatag ttatgaaact cgtcggaagg tgcggagctg
     6001 aagcccaact tggcatcgag cagattttcc cactgcacct tttcacggtc attatagttg
     6061 gcaaacaatt gcaggttggc aagcacggcg ttagtgctct cacctccctt gtaccagttg
     6121 tcggagatat agttctgggt aatctgcaat gaaccgtttc cacccgtcac ccaccagttg
     6181 ggcttgtgga taatcacgtc ggcttcctcc ttcactccca ccatattctc ttgtgcaaac
     6241 agtttcacga cggacggctt ggaagaaacc tccttctcta tattatcctt gaatatcttc
     6301 cctttcatca cctccttctc ggtcattaca accagattgg gacaattcac atacgtgttc
     6361 agcagcgtac ggtccaccag tttgttggct cggtcctttg aggtgaaact cagtgtgtcg
     6421 aacggcaaca tctcgcgcgt cagggcaggc accgtatcag gcacctggaa atgccagtcc
     6481 accttggaaa ggcgtctcat gggggcataa taataggtaa ggggaaggaa caacctatag
     6541 tagttcggat tggaaggtat ataacgctcc ggagtcgtgg ggtcattcaa ataatccagc
     6601 actccgatat acctttcata taatatggaa acagtatcca gcctgtaccc cataccttcc
     6661 ggtttcaatt tcagaatcat gtattctttc attatatccg gcaaggtgtc ggctttggca
     6721 gttgtttcct gtccactgtt cttcgaggcg gtatccagcg tattctgtgc catcaccgac
     6781 gaagaaatca tcgtagcaat taaccaaaat gcaatgtgtc tattcttcat aatgccctaa
     6841 agtctatgtt tcgagcgcaa atttagctta aaatgtttag aaaacataga aaagccataa
     6901 gaaaaaggca agaaggactt tcttcgatga aatcgtattt tttaataatt gtttcatcga
     6961 aactttctct acttcctctt ttttttataa ttttgcgctt tttaagttct acgtgtactg
     7021 acgggagcag tgcgcaccct gaacgacaag ccgtataggc tcttggcatt agattaaaca
     7081 attaataaaa taatatagtt gtgggagaaa caaagtatat tttcgtcacc ggtggtgttg
     7141 cctcttcatt aggtaaaggt atcatctcat cctccatcgg taaattgctg caagcaagag
     7201 gttacaaggt aaccatccag aagtttgacc cgtacatcaa catcgacccg ggtacactga
     7261 acccttatga acacggcgaa tgctacgtta ccgtggatgg gcacgaagcc gacctcgatt
     7321 tgggccatta cgaacgcttc ctgggcatcc agaccaccaa ggccaacaat atcacgaccg
     7381 gacgcatcta caaaagcgtc atcgacaaag agcgccgggg tgactatctg ggaaagacca
     7441 tccaggttat tccccatatt acagacgaaa tcaagcgtaa tgtaaaactg ctgggaaaca
     7501 aatacaaatt cgactttgtt attaccgaga ttggcggtac agtgggtgac atcgagtctc
     7561 tgccctatct ggaaagcatc cgtcagctga agtgggaact gggaaaagac gccttgtgcg
     7621 tacaccttac ttatgtcccc tacctggctg ctgccggtga actgaagacc aagcccaccc
     7681 agcactccgt aaaggaactg caaagtgccg gtatccaacc tgatgtcctc gtactgcgta
     7741 cggaacacga gttgagtacc accctgcgca agaaagtggc tctgttctgc aatgtggacg
     7801 aaaatgccgt ggtgcagagc atcgacgcgc ctaccatcta cgaggtgccc atcttgatgc
     7861 agagccaggg actggacgtt accattttga agaaaatggg acttcccgtc ggcgacactc
     7921 cgggactggg accgtggcgc gctttcctcg aacgccgtca caaagccgaa gagactgccc
     7981 cgctgcacat cgcattggtg ggcaaatatg acttgcagga tgcctacaag tccatccgcg
     8041 aggccctttc acaagcagga acctacaatg accgcaaggt atcggtagac ttcgtgaaca
     8101 gtgaaaagct gactgacgag aatgtggcag aagccctgaa aggcatggca ggcgtactta
     8161 tcggtccagg cttcggcgaa cgcggcgttg ccggcaagtt cgtagccatc aaatatgcgc
     8221 gtacgcacga catccccacc ttcggtatct gtctgggtat gcagtgtatc gccatcgaat
     8281 ttgcccgtaa cgtactgggt tatgccgatg ccaactcacg tgagatggac gaaaagacac
     8341 cgcacaatgt catcgacatc atggaagagc agaagtccat caccaatatg ggtggaacca
     8401 tgcgtctggg tgcctatgaa tgtgttctgc agaaaggcag caaggcatac gaggcatacg
     8461 gtaccgagca tatccaggag cgtcaccgtc accgctacga gttcaacaac agcttcaagg
     8521 aggcctacga agcagcaggc atgaagtgtg tgggtataaa ccccgaatcg gacctggtag
     8581 aaattgtcga aatacccgca ttgaagtggt ttgtcggtac ccagttccat cccgaataca
     8641 gcagtacggt attgcatccg cacccgctgt tcgtagcatt cgtgaaggcc gccatcgaaa
     8701 atgaaaacga aaagaaataa tttgtaataa gtaatttgta atcaacaaag aatggataaa
     8761 aataccatca caggtcttgt tctgatagcg atattgttag taggtttcag ctttctgagc
     8821 cgtcccagcc aggagcagtt ggaagcacag caacgttact acgactccat agcccaggtg
     8881 caacagcgcg aagccgactt gaaagccaag gcggaagcag ccctggccaa cgaaagcgga
     8941 gcggaagcaa gcgttgactc cactgccctc ttcttcgacg cccgtcaagg aaccaactcg
     9001 caggtaacca tccagaacaa cctggcagaa ataaccgtag atacaaaagg cgggcgcata
     9061 gcttcggcca cgctgaagga atacatggga caagacaaga cgacccccgt cacactgttc
     9121 agcggcaatg acgcttccat gaatttcctc ttttacaaca agaaagagac tatccagacg
     9181 gaagactatt atttcaccgc agtaaaccgt acggacagta ccgtcaccat gcgtttgtcg
     9241 gcagacagca acagctatat cgactttacc tacagcatgc acaatgacac atacctgata
     9301 gactttacta tccaggcagt caatatggaa ggcaagctgg ccgccaccaa caattatgtg
     9361 gacatcgagt ggtctcagcg tgcccgtcag atagagaagg gttacaccta cgagaaccgt
     9421 ctggctgagc tgacttacaa aatcgccgga gagggtaccg attatctgtc tgccaacaag
     9481 aacgatgaaa aggaagttcc ggaacgcctg gactggattg ctttcaagaa ccagttcttc
     9541 tcttcagtat ttttggcaga tgccgacttt gaaaagacca agctgagttc caagatggag
     9601 actcaaggca gcggctacat caaggactat tctgcagaga tgagcacgaa gttcgaccct
     9661 gctggcaagg aacctaccca gctgttcttt tacttcggcc ccaatcacta caagactctg
     9721 accgcactcg acaagggacg tgacgccaag tgggagctga accgtctggt ctatctgggc
     9781 tggccgctca tccgctggat aaacaaatgg ttcaccatca acatcttcga ctggttgtcc
     9841 agttgggggt tgagcatggg tatcgtactg ttgttcatga cgttaatcgt aaaagctgta
     9901 gtattccccg caacgtggaa aacctacatg tcctctgcca agatgcgcgt actgaaaccg
     9961 aaaatcgacg agataaacaa gaagtacccc aagcaggaag atgccatgaa gaagcagcag
    10021 gaagtgatgg gcctctacag ccagtacgga gtcagtccga tgggtggatg tctgccgatg
    10081 ctgatacagt tccctatctt gatggccttg ttcatgttcg tgccgagtgc cattgaactc
    10141 cgccagcaga gcttcttgtg ggcagacgac ctttccactt acgatgcgtt catcaacttc
    10201 ccgttccata tcccgttcct gggaagccac ctcagcttgt tctgcctgct gatgacggtt
    10261 accaacatat tgaacacgaa gtacatgatg cagcagcagg atacgggtgc caatccgcag
    10321 atggctgcca tgaagtggat gtcatacctg atgcctatca tgttcctctt catattgaac
    10381 gattatcctt cgggattgaa ctattactac ttcatctcta cgttaatcag tgtggtaaca
    10441 acgctcatca tgcgcaagac aaccaatgag gaagcccttc ttgcccagtt ggaagccaac
    10501 aagaaagacc cgaagaagat gaagaaaacc ggtttcgccg cccgtctgga agccatgcag
    10561 aaacagcagg aacagatgat gaaagagaga cagaacaaaa agtagtaaga ctaccgttca
    10621 agatattctt ttgcagaaag ccggacaatg acatttgccc ggctttctta tccttacgcc
    10681 aatgaaaaaa ctcacagact ctaaattatg cagactaaat acacctacaa acagatctgg
    10741 cttatagcct accccatcct aatcagcctc cttatggagc aactgatagg tatgacggac
    10801 actgccttcc tcgggcgtgt gggcgaagtc gaactgggag catctgccat cgccggtgtc
    10861 ttctacatgg tcatcttcat ggttgccttc ggtttcagca tcggggcaca gatactcatt
    10921 gcccggcgca acggcgaacg gcagtataag gaaatcggtg acttgttcta tcagggcatc
    10981 tatttccaag tcggaatggc ggcagtcatg ttcctgctat cctattgttt ctcaccgatt
    11041 atcctgaaac gcatcgtcgc ttcggaacat atctacgaag cagccaccag ctacctgcat
    11101 tggcgtgtat tcggtgcctt cttctcgttc agcgcagtca tgttccgtgc ctttttcttg
    11161 ggaaccaccc agaccaagac actgacactg aactccatcg tcatggtgtt gagcaatgtc
    11221 gtattcaact atatcctgat tttcggtaaa ttcggtttcc cggcgctcgg cattgccgga
    11281 gccgccatcg gctcctcact ggccgagctg gtttcgctgt tattcttcat cctctatacc
    11341 cgcagccgca tcgactgccg caagtacggg ctggatcgta ttcctaagtt ccggctggac
    11401 gtattgaaac ggatgctgaa cgtctctttc tggaccatga tacagaattt cttctccctc
    11461 tccacctggt tccttttctt cctttatgtg gagcatctgg gagagcgctc gctggcagtg
    11521 accaacattg tccgcaacgt gtccggcata ctgttcatgg tactcatggc gtttgcctct
    11581 acctgcgggt cactggtcag caacctcatc ggtgcaggcc actccgattg cgtggcaggc
    11641 accatccggc agcacgtacg catagcctac gtcttcgtac ttccgctggc attgcttttc
    11701 gcggtgttcc ccaagctgat tctgggaatt tataccgaca tacccgacct gcaggacgct
    11761 tccgtgcatt cgctctgggc gatgtgctcc acctatctgt tcctggttcc tgccaatgtc
    11821 tatttccagg cagtttccgg aaccggcaac acgcgtacgg catgggggtt ggagatggct
    11881 acgctggtca tctacacagc ctatatcacc tacattattc tgattctgca actcgacgtg
    11941 gccatttgct ggacctcgga aatggtttat tccagcttta ttctcatttt ctgctggcta
    12001 tatatcaaac gtgggaattg gcaaggaagg aaaatttagt atctttgcat tgaaataacc
    12061 gaaacaaaaa acatatatga aacaagtaaa tctactactt atgtcagcag ccatgacatt
    12121 ggcctcctgc ggaggaacaa aagatgccgg acagcagcag gacgcagcag cgctcatcca
    12181 gcggtcggac atcaagattg aaggaaagcg tatgacaccc gaggcactct gggcgatggg
    12241 acgtatcggc agtgtagccg tatctcccga cgaaaagcaa attgcctaca cggtatccta
    12301 ttacagcgtg ccccagaaca agagtaacag cgaagtcttc gtcatgaatg ccgacggtag
    12361 tggcaatacc cagataacgc atgacgcctg gcaagaagga cagcccacat ggttcaagga
    12421 cggcaagaag cttgccttcc tttgcaacga aagcggcagc agccaggtat gggaaatgaa
    12481 tcccgacggc agcggacgca agcagctgac ccaatacgag ggagacatcg aagggttctc
    12541 tttctcgccc gacggcaaga aactcctttt cattgcccag gtaaagaccg tgaagagtac
    12601 ggcagacaaa catccggacc ttcctaaagc caccggcatc atcgttaccg acctgatgta
    12661 caagcattgg gatgaatggg tgactactgc tccccatccg tttgttgctg atttcgacgg
    12721 caatgccatc agcaatgtca ctgatattct tgagggagag ccatacgaaa gcccgatgaa
    12781 gccctggggc ggtatcgagc agctggcatg gagcccgtct tctgataaag tggcctatac
    12841 atgccgtaag aaaaccggac tggcgtatgc catttccacc aactccgaca tttatatcta
    12901 cgaccttgcc tccaaggaaa ccaaaaacat cacggaagaa aacaagggat atgatacgaa
    12961 tccccaatac tctcccgacg gcaaatacat cgcctggcag agcatggagc gtgacggcta
    13021 cgaagccgac ttgaaccgct tgtttatcat gaacctcgag accggcgaga aacgttttgt
    13081 aagcaaagct ttcgaatcga acgtggacgc cttcttgtgg aacaaagatt cccagagcat
    13141 ctacttcatc ggtgtatggc atggcgagac acagatttac aacatcgacc ttgccggaaa
    13201 cgacaagctt acccagctca ccgacggcat gtacgactat gcttcgcttg ccctttgcgg
    13261 agacaagatt atcgccaaac gtcattccat gagcatgggc gacgaaatct atgccgtaaa
    13321 cagtgcacgt aacggcgacg cttttgcaga agcagtgcaa ctgaccacag aaaacaagca
    13381 gatttacgac cagctggaga tgggtaaagt ggaagcccgc tggatgaaga ccaccgacgg
    13441 caagcagatg ctgacctggg tgatttatcc tccgcagttc gaccctaaca agaagtaccc
    13501 caccctcctc ttctgtgaag gtggtcctca gagtcccgtc agccagttct ggagctaccg
    13561 ttggaatttc cagattatgg cggcaaacga ctatatcatc gtagctccca accgtcgtgg
    13621 tcttccgggc ttcggtgtag agtggaacga agccatcagc ggtgattatg gcggccagtg
    13681 catgaaggac tacttcactg ccattgacga aatggccaag gaacctttcg tcgacaaaga
    13741 ccgcctgggt tgcgtaggcg ccagcttcgg aggcttctcc gtatattggc ttgccggaca
    13801 ccatgacaaa cgcttcaagg cattcatcgc acacgacggt atcttcaaca tggaaatgca
    13861 atatctggaa acggaagaga aatggtttgc caactgggat atgggcggtg cttattggga
    13921 aaagaacaac gctacggcac aacgcacttt cgccaactcc ccgcacctct ttgtcgacaa
    13981 atgggacacc cctatcctct gcatccacgg agagaaggac ttccgcatcc ttgccaacca
    14041 ggcaatggcc gccttcgatg cagccgtgat gcgtggcgtt cctgccgaac tgcttatcta
    14101 tccggacgaa aaccactggg tactgaaacc tcagaatggc gtgctgtggc aacgtacctt
    14161 ctttgaatgg ctggacaaat ggttgaagcc ggctaagtaa agcccctcaa aaacgataaa
    14221 aacaaatagt cccggattct tgacaaagaa tccgggacta tttgttttta ttgtacaccg
    14281 cccgattcat tttttatgac tataatttga aagtattagg tgtaatacgt accttgatag
    14341 aagtccaaga aaaaatcaaa tctcatcccg atttaaagaa acgttacttt cttaagcctg
    14401 atgaagttat tttattggca gacggaacaa aaattgttgt caacaaccag tggggaacat
    14461 tatttccaag atttcttgaa gcagcaaaga aactatacca agtaaccaat gatacggaaa
    14521 gcaatactcc aatatcccgg ttaaaaatta cttttggtaa tgggaaagta attcaagaaa
    14581 cacaagcagc cgagactttc cggcaatttg tgatgacagt aggtgtggaa caagtgcaat
    14641 ctttaaatat caaggtatgc aagattccct tgatatcaaa cacacttcat gagaaatacc
    14701 agc
//
