LOCUS       gnlProkkaDEAPHNHP_23    5552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DEAPHNHP_23.
ACCESSION   gnlProkkaDEAPHNHP_23
VERSION     gnlProkkaDEAPHNHP_23
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:31:18
            Original ID  :: gnl|Prokka|DEAPHNHP_23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5552
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1041
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MIYYIIGLLTFSEVALLGFALLPVPLKVCSIFLSGLPLGMIWGVI
                     FSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMDNLHVSEYWMPFTTGLLVYPVML
                     LCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQFFWGICMLVVFYGALTVFRELR
                     DSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLIVFVRNNRLALNIIYCIAVTGGS
                     LMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYLIERLIASLRVVSTAVFIIYLAD
                     SFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFVSVLSIFAIYCYFKQQLNSLILI
                     PSEIHD"
     protocluster    1..5552
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1054:5319]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1055..5319
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5552
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1055..1753
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             1773..3074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_3"
                     /sec_met_domain="CTP_transf_like (E-value: 7.6e-13,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 5.5e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.8e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3086..4222
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 69.7;
                     E-value: 3.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 4.2e-23, bitscore:
                     70.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHVIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4219..5319
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg23_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="Aminotran_5 (E-value: 4.6e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVLKY"
     aSDomain        4309..5097
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg23_5_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg23_5_Aminotran_5.1"
                     /locus_tag="ctg23_5"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             5339..5551
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MKDKKNVVKWNFVFYLLEFLYTILVGIILVPLYLKYIPKDLYGFW
                     LATGNILSILTLINPGFSDVIQQKVA"
ORIGIN
        1 cgcatctatt atataatagg gctgcttact ttttccgaag ttgctttgtt gggttttgca
       61 cttcttccgg ttcctttgaa ggtgtgttct atttttctga gcggtcttcc cctgggtatg
      121 atctggggtg tcatttttag ctatatcgaa ggacgtcgta tcagtgaaat attgaatgtc
      181 gggctgagcg ttgctttgat agtctcttcc ggtttggtga aaaccttggg acaattcgtg
      241 atggataatt tgcatgtgtc ggaatattgg atgcctttta ccacaggttt gttggtatac
      301 cctgttatgt tgctttgcag ctggcttctc aatcagattc cggctcccaa tgagcaagat
      361 atcatacagc gtaccaaacg tgctccgatg gatggtaaag acaggcgtaa atttttgagg
      421 caattcttct ggggaatctg catgctggtt gttttttacg gtgccctgac cgtgttccgt
      481 gagcttcgtg actctttcgc tgccgatatt tggaaggagc tccatattga aggtgcaatg
      541 atctttactc agacagaggt tcccattgcc gtttttgtcc ttgtactgat gttcctgatt
      601 gtgtttgtcc gtaataaccg tttggctctt aatatcattt attgcattgc cgttacaggc
      661 ggttccttaa tggttttttc cacattgctt tatgtgtacg gttttctttc tcctatttgg
      721 tggatgattc tttccggtct tggtctgtat atggggtata ttcctttcac ttacctgata
      781 gaacgcctga ttgcttccct tagggtggtt agtacggctg tttttattat ttatttggcc
      841 gattctttcg gctatctggg cactacgggt gtgtttatgg tcaagaactt cgtttctgct
      901 gacatttcct ggactgtcat gctgatgcgt actgcccttt tttcaggatt tgtttctgtc
      961 ctgtcgattt ttgcgattta ctgttatttc aagcaacaat tgaattcact tatattaatt
     1021 ccctctgaaa ttcatgatta aaacagcaat gatcatggct gccggtcttg gtacccgctt
     1081 cgggcattat accgagcttg tgcccaaagg ttttgtggag gttggtggaa aacctatgat
     1141 tatccgctct atcgaaaccc ttctttcctg cggtatcgaa cgtatcatcc tcggtacggg
     1201 ttataaaaaa gaggcttatg aagcccttca ggcggatttc ccccagatag agacctgttt
     1261 cagtccccgt tatgccgata ctaacagtat gtacactctg tacaatacgc gtgacgtgat
     1321 aggcgatgac agtttcctgc tgcttgaatc ggaccttgtt tttgaacgca aggccatcct
     1381 ctcgctactg gatgacgaat tcccggatgt gatgcttgtc tcttctctga ccaagttcca
     1441 ggatcagtat tatgtggaat acgaccgcaa tcacatcctt acttcctgtt cggtagacaa
     1501 ggacgccctt gaggcaaaag gcgagctggt cggtatccat aaactttcca atactttcta
     1561 ccgccggatg tgcgccgatt atgcgaccat cctggagtcc cagcctaaac tgggttacga
     1621 gtacgaactg ctccgcatgt cccgttccgt ttcccctgtc cgtgtgctca gggtggaggg
     1681 tcttaaatgg tatgaaatcg atgatgaagc cgacctttcg tatgccgagg agcacatcat
     1741 ccgctattgt taaaaacaaa tcttttccat atatgaacaa gaaaatctat gtcggtatga
     1801 ccgcggatat catgcatccg gggctgatcc atattattca tgaagctact aaatacggtg
     1861 atgtcatcgt cggtctgctg acggacaagg ccatcgccga acacaaacgc ctcccttacc
     1921 ttacctatga tcagcgtaag gaggttgttg agaatatcaa gggggttttt gaggttgttc
     1981 cccaggagga ctggagctat gttccgaatc tggaaaaact caagcctgac tatatcatcc
     2041 acggcgacga ctggaaaacg ggcccgttgc gcgaggtgcg cgaacaggtt tttgaggtga
     2101 tgaacgccca ggggggcaag gtaatcgaga tcccttatac ccggggcatc aactcctcct
     2161 cgctcgacaa ggatatcaag gcgatcggga ctacccctga cgtacgtctt aagtccctcc
     2221 gccgcctgat ccaggccaag cctgtggtcc gtatcctgga ggctcacgac ggtctttgcg
     2281 gtctgattat tgagaatctt gaagtccaga agggtgataa gcgcgaggtc tttgacggca
     2341 tgtggtccag cagcctgacc gactccacga gtaaaggtaa accggatatt gaagcggtcg
     2401 accttaccac ccgtttacag gacctgaaca atatccttga atgcaccacc aagcctatta
     2461 tttttgatgg agacacgggt ggcaagatcg aacactttgt ctttactgtg cgcactctgg
     2521 aacgtcacgg catttctgcg gtaatcattg aagataaagt cggtctgaag aagaattccc
     2581 tttttggtac tgacgctatc cagactcagg atagtatcga gggtttctgc gataagatca
     2641 gagcagggaa gaatgcccag gtcaccggtg actttatgat cattgcgcgt atcgaaagcc
     2701 ttattgccgg caaacccatg agtgacgccc tcgaacgtgc ttatgcctat gtacaggcgg
     2761 gtgcggacgg catcatgatc cacagcaagg ataagtcggg tgaggatatc cgtgagttct
     2821 gccggacttt ccgcaaagaa tacgcccatg ttcccattgt cgttgttccg acgacttatg
     2881 accatgtgca cgaatccgaa cttcacgaat ggggtgccaa cgtagtcatt tacgccaacc
     2941 accttctccg tgccgcttac ccggccatga tgaacgtggc caggaccatc cttgaaaacg
     3001 agcgcgccga ggaggtccgt ccgctttgta tgcctatcaa ggaaattctg gaattgattc
     3061 cgggcactaa ataaatcaga cggttatggt aagtgtagaa aagatatacg atacgttcct
     3121 tcatcacggt gttgacttct ttacgggtgt tcccgattcc cttttgaaga atatttgcgc
     3181 ctatatcacg gatcatgctc cgcgtggtaa gcatatcatc gccgccaatg aaggttccgc
     3241 ggtgggcatt gcctgcggtt attatatggc ttctggcaac gttcctttgg tttatatgca
     3301 gaactccggt ctgggaaata cggtgaatcc cctcttgtcc cttgcggacg agaaagtgta
     3361 cagccttcct cttcttttgc tggtcggctg gcgcggtgag cccggcacga aagacgaacc
     3421 ccagcataag aagcagggcg aggttaccct tgatcttctg aaagccatga aaattccttt
     3481 tataattctg gatacggatg aagacgaggc cctggcgcag atccatgatg cggttgtctc
     3541 ggcgaagagc cggtcgattc cccatgtgat tgtcatccgt aaagatacgt ttggaaaata
     3601 taaattgcgt caggaagcct tgaatgacta tcctctgtcc cgcgaggagg cgttaatgca
     3661 ggttgtcgac cacctcgggg acaatgacat tgtggtttcc accacgggca agctctcccg
     3721 tgagcttttc gagtaccgtg aatcgaaagg gcaggggcac gcaagggatt tcctaactgt
     3781 gggttccatg ggtcacagtt cttccattgc cctggggatt gcccttgaga agcctgaccg
     3841 ccgtgtctac tgtcttgacg gtgacggtgc ctttatcatg cacatgggtg ctgtcagcaa
     3901 tatcggcgat ctttctccca agaattacag gcacgtcctt ttcaacaacg gtgcccatga
     3961 atctgtcggc ggtcaaccca cgctcggttt ccgtctggat atcgcctcga tagcgaaagg
     4021 ttgcggttat gcgcatgtac tgactgcctc cgacaaggaa gggctttcgt gtgcgcttga
     4081 gaagctgtcc ggcctgtccg gcccggttct tcttgaaatt aaggtccgga tcgattcacg
     4141 tgatgatctg ggtcgcccta cgactactcc ggtagagaat aaagagcatt ttatggcatt
     4201 tttaaaagat acgcattcat gaatatcgaa agaaagatcc ttttgaatcc gggtcccgcc
     4261 accacgacgg atacggtaaa gctggcgcag gttgttcccg atatctgtcc gcgtgagaaa
     4321 gagtttgcgg gtatgatgaa acagttacgt gacgacctgg tccgcgttgc gcatggagac
     4381 ctctccaaac atacggccgt cctgttttgc ggctcgggta cgatcaatat cgatatctgc
     4441 ctgaactctc ttcttcctgc ggataagaaa gttctggttg tcaataacgg tgcctatagc
     4501 acccgtgcgg tggaagtctg cgaatattac ggtcttcccc atatcgattt gaagttttcc
     4561 gtttacgaac ttcccgacct gtcggtaatc gaaaagacgc tttccgacaa tccggacatc
     4621 gctttggtct ataccacgca ccatgaaacg ggtacgggta tcttgaaccc catccgtgag
     4681 atcggaaaaa tagcccattc gcacggtgcc gtttttgttg tcgacaccac ttcctccctg
     4741 ggtatgattc cttttgatat cgggaaggat aatgttgact tttgtatggc ttcggctcag
     4801 aaaggccttc aggccatgac gggtctttcc tttatcatag gtgatgaatc cctgatacgt
     4861 gcttcaaggg attatccgaa acgctcctac tattgtaacc tctatttaca atacgattac
     4921 tttgagaaga cgggtgagat gcattttact cctcctgttc aaaccgttta cgctgcccgt
     4981 caggctcttg atgaatattt tgcagtaggt gaagaggcta aattcgcccg tcacaagagg
     5041 gtctttgaag ccatccataa aggtttgcaa gagcttggtc ttcagtatgc gatcaaacgt
     5101 gaatggcagt cgggtcttgt tgtttctgta ttgtatcctg atgatcccct ctgggatttt
     5161 gataaggttc atgattactg ctatgaacgt ggctttacga tctacccggg taagatttcc
     5221 acaacgaata cattccggct ttgtgcgttg ggagagattg atgtggagga tattgagagg
     5281 ttctttgagg tgatgaggga ggctgtttta aaatactaga gaaattgtca attgggatat
     5341 gaaagataaa aaaaatgtag taaaatggaa ttttgtattt tatctcttgg aatttttgta
     5401 tacaatttta gttgggatta ttttggttcc gttgtatttg aaatatattc caaaggattt
     5461 atatggtttc tggctagcta ctggtaatat attgtctatt ttaactctta tcaatcctgg
     5521 gttttcagat gtgatacaac aaaaagttgc at
//
