LOCUS       c00498_gnlPro..         4319 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KELFKKGH_498.
ACCESSION   c00498_gnlPro..
VERSION     c00498_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:19:50
            Original ID  :: gnl|Prokka|KELFKKGH_498
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4319
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4319
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4160]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4160
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4319
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4319
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..1034)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg498_1"
                     /sec_met_domain="IlvN (E-value: 3.4e-47, bitscore: 148.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.7e-42, bitscore: 131.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYNSVKTGNEAQISIDSNSQPDYREKLNEELRQLRESEMWQTAVTVR
                     KLRP"
     CDS             complement(1102..1845)
                     /locus_tag="ctg498_2"
                     /transl_table=11
                     /translation="MSEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVVCRSKVIFE"
     CDS             complement(1851..2408)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg498_3"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEEVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             complement(2466..4160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg498_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-48, bitscore:
                     152.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRVFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             4208..4318
                     /locus_tag="ctg498_5"
                     /transl_table=11
                     /translation="MTVENEWFTIIALSAAQLTITYQLSPTILYNSHCSLI"
ORIGIN
        1 tccggacgaa gtttacgaac agttacagca gtctgccaca tttcgctctc gcgtaattga
       61 cggagttctt cgttcaattt ttcacgataa tcaggttgtg aattactgtc gatagaaatc
      121 tgtgcttcat taccagtctt cacactgtta tacaactttt caactaccgg tttgatagca
      181 tcgtggaatg ggcccatcca atcgagagca ccacgttgag cagtagtaga gcagttagcg
      241 tacatccagt ccataccgtt ctttgcaaac aacggcatca acgactgtgt cagttcttcc
      301 actgtttcat tgaatgcttc agaaggacta tgaccgtttt cacgcaatac ttcgtactgt
      361 gccagcaaca aaccttggat agcacccatc aatgaaccac gttcacctgt caagtcagaa
      421 gtagcttcac gttggaaagt tgtttcgaac agataaccgg aaccgatacc gatacctagt
      481 gcgatagttc tttcgtaagc cttgcctgta gcatcctgat agatagcata agaagagttc
      541 aagccacgtc cttcgaggaa catagtacgc aaagatgtac ccgaaccttt aggagcaacc
      601 atgataacgt cgatatcagc aggaggaact acacctgtac ggtcgttcca agtgatagca
      661 aaaccgtgtg agaaataaag agcttttccg gcagtcaggt aaggcttgat agtaggccat
      721 actgacatta ctgctgcgtc agacaacaga cacattacaa tagtaccttt ctcacaagct
      781 tcttcgatac cgaacaaagt ttcacccgga acccatccgt ctgctactgc cttatcgtat
      841 gtttttcctt cacgttgacc aacgattaca ttgaaaccgt tatcacgcaa gttcagtgcc
      901 tgtccaggac cctgtacgcc ataaccgatt acagcgattg tttcattttt caatacttca
      961 cgagcttttt ccaatggaaa ttcgtcacgg attactacag tttcagtagt acctccaaaa
     1021 ttcaactgtg ccattttctt tttgttttta gtttttgatg acttacgcca tctgttatta
     1081 attgatttta tattctcaca tttattcaaa tatcactttc gagcggcaaa caacttcgtt
     1141 gccattcttc ttcacttcta cgtgaaactc gtttgcgttc acttcatcgc agaagaaaga
     1201 gagttcatca ccaaaatagc tttccgccac atacgccatt tcaaaacgac ggatacgttt
     1261 ggtcttatac aattcaatcg ggaacaaatc aaggatatgc tcgatgtaac ggatgctgtt
     1321 tacatgaccg ttgatatcta tatcactgta ttttgccgtc agggtagcta tcggctgatc
     1381 gcttgtcact ttgatgcgtg aaggcttttc aatcgggcaa ggctcatcac agacatagtc
     1441 tacgatactt cccccatgca aagtcaacaa gtcggcaggc ttgcgggtat taagattaat
     1501 cattgcccat acggaacgtg cgtagccaat cttcttccca tccttatcaa taatagcaaa
     1561 attacggtcc gtaaacaagc ggtagacatt ttccacccac gtctgaaccg agaaattctc
     1621 atactgataa ggcatttcat ccaactcaat agccagacgt gaaagcaccc atgtataatt
     1681 gtcctcattc agcgttgcaa taccaaaacc acggtcattg gcgtgaaaac ctgcacaatt
     1741 cagcagatga tttcccagta cccccatagt cagacgtccg ttgaagtcaa catggaacgg
     1801 ttctgccaca aactgataag tccctattct attttcttca ctcattattc ttattggttt
     1861 ttactttggt tatacatagc ttcccgtcca tcgagaaact cattcacccg ttcaaagcag
     1921 ctggtagtaa tcgctacacg tcccgaacga acaaactgca aaacacaatt caaagccttc
     1981 agttcaccat agagcgaagt tatatcttcg ctcattccat ttttctcgac aatagaaaat
     2041 accggattga cttccactat acgtgcattg tatctacgaa tcagcttgga tgcttccgga
     2101 ttctcctgaa aagcaggagt agacacctta tataatgcaa tctcgtggaa ataaatctca
     2161 tcctctgtga aataatgtgc ctgaatcacg tcgatcttct tttcgatctg tttcactacc
     2221 tcctcaatga tgtccttatc agtccaggct gttattgtat acttatgtac acctttaata
     2281 gaagaagcag atacattcag actctcaata tttatttgcc gacgggtaaa tacagcagtt
     2341 acctgattca gcaacccagc tatattctcc gaatgaacaa tgattgtata taacgtttta
     2401 tcactcataa ctctaatttt ttaaatgcga actctcaact ctccattctc aactctcaac
     2461 ttctcctagc actccagcaa catctggttt accgaaccac ccggaggagt catcggcaaa
     2521 acattgcctt cttccaccac gcaggcttcg agcaggaacg gaccgtccgt tgccagcatt
     2581 tcagcaatag cttccttcag ttcttcacga gtgaaaacac gcttggaagg aatatcataa
     2641 gccgaggcca ctttcatata atccggattc aacatcgggg tgaacgaata gcgacggttg
     2701 aaaaacatag cttgccactg acgtacgttt ccgaggtaat tattgttcaa gcagataatc
     2761 ttcaccggag ccttctgctc cataatcgta cccagttcct gaatattcat ttgcagtccg
     2821 ccatctccca taaatacgca tacggtacgt tccggtgctc cgaaagttgc cccgatagct
     2881 gcgggaagcc cgaagcccat tgttccaagt cctccggaag taatgatact gcgttctttc
     2941 gtatatttaa agtagcgtgc agatatcatc tgattttgac ctacatctgt taccaaaaca
     3001 gcttcatggt gagtagcgtc acttaccgca cgtaccactt cccccatact caaagagttt
     3061 gtggcaggat gaagttcagg acggattact ttttcctcct ctactttctc atattctttg
     3121 aagctatcaa tccattcggt atgagtgttc tttttcagaa gtttcgtcac agaagccagt
     3181 gtttccttgc aatctcccaa tacagctaca tctaccttta cattcttatt aacttccgca
     3241 ggatcgatat caaaatgaat cacttttgcc tgtttggcat aagtagccaa attaccggtc
     3301 acacggtcgt caaaacgcat accgacagca atcagcacat cacatttatt ggtattgata
     3361 ttcggtccca gattgccgtg catacccaac atacctttat tcaacggatg ttctgtcggc
     3421 aaagccgaaa gtccgagcag cgtacaaccc gcaggcatat ccgctttttc gataaactcg
     3481 cgcaattcgc tctgtgcatt tcccagttca acaccttgtc caaccaatac aagcggacgt
     3541 tcagcgttat taatcagttc ggcagcagcc tgtacagtct cctcgtccgt atcgggaaca
     3601 ggaacataac tacggataaa atcgactttc gtcggttcgt atttcgtttt ctctacttgc
     3661 gcatttttgg caaagtccaa taccaccggc cccggacgac cactacgagc aatgtaaaac
     3721 gcacgtgcta ccgcccaggc tacatcttcc gcacggcgaa tctgataact ccatttagtg
     3781 attggctggg tgatacctac caagtcaact tcctgaaaag catccgtccc aagaaagcct
     3841 gttcctacct gtccggcaat caccacgata ggcgtactat cgatcatcgc atccgcaatg
     3901 cctgttaccg tattggttgc tccgggaccg ctcgtcacca ggcaaacacc tacatcaccc
     3961 gatacacggg cataaccttg tgcggcatgg gcggctccct gctcgtgacg aaccaagata
     4021 tggttcaata tattttgatg atcgtacaag gcatcgaata ccggcataat agaaccaccg
     4081 gggtaaccaa agatggtagt cactccctga tgttccaagg agcgcatcaa agcctctgca
     4141 cctgttatta aatctttcat attagttgat agttgataaa tgataaatga taaatgatag
     4201 ttgagaaatg acagttgaaa atgaatggtt tacaatcatt gcgctaagtg ctgcgcagct
     4261 aactattacc tatcaactat caccaactat attatataat tctcactgct cccttatcg
//
