LOCUS       c00247_gnlPro..        12763 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CEHKHCCC_247.
ACCESSION   c00247_gnlPro..
VERSION     c00247_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 09:41:56
            Original ID  :: gnl|Prokka|CEHKHCCC_247
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12763
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12763
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3990:6949]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3991..6949
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12763
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12763
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..364)
                     /locus_tag="ctg247_1"
                     /transl_table=11
                     /translation="MEATTLSAARVYVGTYGKYNAGSLFGEWLDLSDYSDKEEFYDACR
                     ELHKDEEDAEFMFQDWENVPENLIGESWLSENFFALRDAVEDLGDTEQEAFFVWCNYKS
                     HDLGEEDADDLVRDFRD"
     CDS             complement(978..1475)
                     /locus_tag="ctg247_2"
                     /transl_table=11
                     /translation="MDLQIIQNKIFEIRGYRVMLDFHLAELYGVQTKALKQAVKRNEKR
                     FPPDFRFTMTKEEWDELVTICDQLPESLKHSYILPDCFTEQGVAMLSSVLRSQTAIDVN
                     ISIMRAFVLMRQMVIGYEELLKRIEELEVSTDAQFNEIYQALTQLLSQSQQQKERRPIG
                     FR"
     CDS             complement(1487..2071)
                     /locus_tag="ctg247_3"
                     /transl_table=11
                     /translation="MKRQYHKEYLTREELTAFLKAKLSSEHLEKVRDVFVFSCFTGLVY
                     EDLKKLRAEQLMTLPSGSHYLRIYVPMTRFPRTIPLLDIPYKIIKKYKGQQEDGGLFPL
                     FPLPVMNIRLREIAFECGINKTITTFSARRTFATTIASENGIPLETAAKILGHSLLKST
                     LSVTCFTKNKIASDMSAISGQFKDMETMFNL"
     CDS             complement(2150..3376)
                     /locus_tag="ctg247_4"
                     /transl_table=11
                     /translation="MKSTFKVLFYLKKGSEKKNGEVMIMARITIDGKLCQFSTKQSILP
                     ENWNIAAGKAKGKDAGKINALLEDIKASLNNIYHEQQRRDNYVTAEKVKNEFLGHSEKH
                     ETILNLFKKHNDDVKQLVGISKTIATYRKYEVTRRHLAEFVQSKYNISDIAINEITPMF
                     ITDFELYLRTTCKCGYNTTAKFLQFFKRIILIARNNGILIGDPFVNYKIRLEKVDRGYL
                     SEDEIKIILKKKMVSERLENVRDLFIFSCFTGLAYVDVANLTQENIRKSFDGKLWIITK
                     RQKTNTDVNVPLLDIPKMILKKYKGKLPNGKVLPVISNQKLNAYLKEIADVCGIKKNLT
                     FHLARHTFATTTTLAKGVPIETVSKMLGHTNIETTQIYARITNNKIGNDMQGLDKKFVG
                     IEKIYKEAL"
     CDS             complement(3788..3901)
                     /locus_tag="ctg247_5"
                     /transl_table=11
                     /translation="MLNSIKIPIYGEKLDSSYYFQIYFSNIFLRNNLQVKK"
     CDS             3991..6219
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg247_6"
                     /sec_met_domain="Gly_radical (E-value: 4.6e-47, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1164.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVETDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             6224..6949
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg247_7"
                     /sec_met_domain="Radical_SAM (E-value: 6.3e-31, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(7182..8441)
                     /locus_tag="ctg247_8"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKQPEAVTEEKRAEPQQEATAAIEK
                     KESVTAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGVVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(8496..9044)
                     /locus_tag="ctg247_9"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             9232..9984
                     /locus_tag="ctg247_10"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(10089..11087)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg247_11"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-46,
                     bitscore: 147.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 9.7e-19, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPYLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             11157..11630
                     /locus_tag="ctg247_12"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(11734..12732)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg247_13"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 2.9e-70,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
ORIGIN
        1 cgtcccggaa atcacgtaca aggtcgtccg catcttcctc gcccaaatca tggcttttat
       61 agttgcacca cacgaaaaag gcttcctgct cggtgtcgcc taaatcttcc accgcatcac
      121 gcaaagcgaa aaagttttcc gaaagccagc tttcgccgat taagttctcc ggcacattct
      181 cccagtcctg aaacataaat tcggcatctt cttcgtcctt gtgcaattcc cggcaggcat
      241 cgtaaaattc ttccttgtcc gaatagtccg aaaggtcgag ccactcgcca aaaagtgaac
      301 ctgcattgta cttgccgtat gtgcctacat aaactcttgc tgctgataat gtcgttgctt
      361 ccatgattgt aattttttta agttcatgcg gatttgagag gtgagggagt tgagtttcat
      421 aacctttttc ctgtttctcg taaatccgac ttttttttta tgcgtcttcc ggtcgggtcg
      481 gtcgttttcg tttcacatag gcgtaaaagg gtagtgttta gactttgcaa gtttttggca
      541 aaaaatacct cgcaaccagc gggcgcaggg aagatttttt gccaaacctg aaaggctcga
      601 acttgcaaag tcgtgaagaa cacgtaacta cctttgccta ttgaaatgat aaaaacgact
      661 gtcccggctg ggggactgct aaagaggaag atttacatta agaggaacag gtaaaaggtc
      721 taatctatat tttgtaggga aagttcctga tgagaactta ttttctaaaa tgggaaaatg
      781 cgggcggcaa agacaagtgt atcgtcagtt tatcttacga taggcttgtg cgggttttca
      841 taggctcttt tttgaaaagc cccgcaagtg gataaacttt tgtgcagcaa cggcggggat
      901 tttggaaaat gtgccggaga aaaaagaata gcgggacgta tgcccgctat tctgatggga
      961 atatttcaat ctattcatta tctaaagcca ataggacggc gttctttctg ctgttgggac
     1021 tggcttaaca actgggtaag ggcttggtag atttcattaa attgtgcatc cgtacttact
     1081 tccagttcct cgatacgttt cagcaattct tcgtagccga ttaccatttg gcgcataagg
     1141 acaaacgccc gcatgatgga tatattcacg tctatggcgg tctgactgcg caacacgctg
     1201 ctaagcatgg caaccccctg ttccgtgaaa caatcgggaa gtatatagct gtgtttcagg
     1261 ctctccggca actggtcaca aattgtgacc agttcgtccc attcctcttt cgtcatggta
     1321 aaacggaagt cgggcgggaa gcgtttttcg ttacgcttta ctgcctgttt caaggctttt
     1381 gtctgtactc cgtaaagttc tgccaaatga aagtcaagca ttacacggta acccctgatt
     1441 tcaaaaattt tgttctgaat gatttgcaag tccataattc tattatttat aaattaaaca
     1501 tggtttccat atctttgaat tgcccggaaa tagcggacat atcactggct atcttgtttt
     1561 tcgtaaagca agtgactgaa agcgtacttt tcaaaagact atgccccaat attttggctg
     1621 cggtttcaag gggaataccg ttttccgaag ctatcgtggt ggcaaatgtc cggcgggctg
     1681 aaaaagtggt gatagttttg tttatgccac attcaaaagc tatttcccgt aaccgaatat
     1741 tcattacagg caaaggaaaa agcggaaaca acccgccgtc ctcttgttgt cctttgtatt
     1801 tcttaattat tttataagga atatccaaca ggggaatagt acggggaaaa cgggtcatag
     1861 gaacatatat tcgcaaatag tggctaccac tgggtaacgt cataagttgc tctgcacgta
     1921 gcttttttaa atcttcataa accagcccgg tgaagcagga gaatacaaaa acatcacgga
     1981 ctttttcaag atgttcggaa gaaagtttag cctttaaaaa ggcggttagt tcttcacggg
     2041 tcagatactc tttatgatac tgtcttttca tgtgcttatt tgttttaaaa gtgagtaata
     2101 ataaggtaga gaacctgccg ttttaacggc aagttcctta tttaaatggt tacagggctt
     2161 ctttataaat cttctcgata ccgacaaatt tcttatcaag tccctgcata tcgttgccta
     2221 tcttattatt ggtaatgcgg gcgtaaattt gcgtggtttc tatattggtg tgtcccaaca
     2281 ttttgctgac cgtttcgatg ggaacaccct ttgcaagcgt ggttgtggtc gcaaatgtgt
     2341 gtcttgcaag gtgaaatgtc aagttctttt taatcccgca aacgtccgct atttctttca
     2401 aatacgcatt aagtttttga ttgctgatta ccggaagtac cttaccgttc ggcagcttgc
     2461 ctttatattt cttcaatatc attttaggaa tatccagcaa aggaacattt acgtctgtat
     2521 tggtcttttg gcgtttggtg attatccata acttgccgtc aaatgatttg cgtatattct
     2581 cttgggtaag gttggcgaca tcaacataag ccaaaccagt gaaacaggaa aagataaaca
     2641 agtccctgac gttttccaac cgttcggaaa ccatcttctt tttaaggatg attttaattt
     2701 catcctctga caaatacccc ctatctactt tctccaaacg gattttataa ttgacgaacg
     2761 ggtcgcctat caggatgccg ttattacggg ctatcaagat aatgcgtttg aagaactgca
     2821 aaaacttggc agtcgtatta taaccacatt tacaggtagt acgcaaatac aactcgaagt
     2881 ctgtaataaa catcggggtg atttcattga tggcaatatc cgatatattg tacttgcttt
     2941 ggacaaactc ggcaaggtgg cggcgggtca cttcatattt acgataggtg gcaatcgtct
     3001 tagatatgcc gaccaactgc ttcacatcgt cattgtgctt tttgaaaagg tttaaaatgg
     3061 tttcgtgttt ttcactgtgt cccaaaaatt catttttcac cttttcggct gtcacatagt
     3121 tatcacgccg ttgttgttcg tggtagatat tattcaggga tgcttttata tcctctaata
     3181 aggcatttat tttgcctgca tctttacctt tggctttacc cgctgcaata ttccagtttt
     3241 cgggcaggat gctttgtttc gtactaaact ggcataactt accgtcaatg gtaattcttg
     3301 ccataatcat aacctcgccg ttcttctttt cagaaccttt ctttaaatag aaaaggactt
     3361 tgaatgtact cttcataacc tcacattttt taagttacaa aactaatgat aacactttaa
     3421 atgtgagata tttagacggt ggacaaattc ggacttcctg cggtcatttt cggacaaatc
     3481 gttaccgttt ttgtccggta gggaataggt aacgatttag taacgaaact atgtcttttc
     3541 aagtcctttt gttgtcttgg aaacaagact tataggcaat aaaaaaacct acaaatcgct
     3601 gatttgtagg tttttgtcct cttactgtcc ttttttgtcc agtaggttct gcggagagac
     3661 agggattcga accccgggta cctcgcagta caacggtttt caagaccgcc gcaatcgacc
     3721 actctgccac ctctccagaa ctacggttaa gtagtgcttt tctcttaaag cgctgcaaag
     3781 gtacgaatca ttttttaact tgcaaattat tccgcaaaaa aatattagaa aagtatattt
     3841 ggaagtaata actgctatct agcttctccc cataaatagg tatttttatg ctattcaaca
     3901 taaaatagga cccttttata tacctaaacc gaaaaaaggt tgtaaatttg cgcgctctaa
     3961 aggataacta accactaact gattaatttt atggaactga ataagacctt taaagatgga
     4021 ctttggagta aagaaatcaa tgtaagggat ttcgttagta acaacatcac tccttatgaa
     4081 ggggatgctt ctttcctgca aggacctacc gaacgcacca aagctgtctg gaatcactgt
     4141 ctcaaagctc tcgaagaaga gagaaacaat aatggtattc gtgcactcga ctacacaact
     4201 gtatctacta taacctctca ccctgccggc tacatcgata aagagaacga actgatcgtc
     4261 ggactacaga ccgatcaggt gttaaaacgt gccatcaaac cgtttggcgg aatcaatgtg
     4321 gttatgaaag cttgccgtga aaacggagtg gaagtagatg acagagttaa ggatatcttc
     4381 actcactatc gcaagactca caatgatggg gtattcgatg tgtataccga agaaattcgt
     4441 tcgttccgtt cattgggatt ccttaccgga cttcccgaca actatgcacg cggacgtatc
     4501 atcggtgatt atcgccgcct ggctctctat ggtcttgacc gtctgataga agctaaaaaa
     4561 gaagatctgc ataatctgac aggtcctatg actgaagccc gcattcgtct tcgcgaagaa
     4621 gtagccgagc aaatcaaggc cctgaaagag attaaagtat tgggcgaata ttatggtttg
     4681 gatctgagcc gaccggcata taccgcacag gaagctgtac aatgggtgta tatggcttat
     4741 ctggctgccg taaaagagca ggatggtgct gccatgtcac tgggtaatgt atcttcattc
     4801 ctcgacatct atcttgaata tgaattaagc cagggtacga taaccgaaac attcgctcag
     4861 gaactgatcg accaattcgt tatcaaactc cgtatggtac gccacttgcg tatgcagtcg
     4921 tacaacgata tttttgcggg tgatcccaca tgggtgaccg aatctatcgg tggacgtttc
     4981 aatgatggac gtaccaaagt tactaaaact tctttccgct tcttgcagac actttataac
     5041 ttaggcccgt caccggaacc taacatgact gtactatgga gccctgagtt gcccgaaggt
     5101 ttcaaagcat tctgtgcaca agtatctatc gacacttctt ccgtacaata cgaaaacgac
     5161 gacctgatgc gtgaagtccg tcaatcggat gactacggaa tcgcttgttg tgtttcatat
     5221 caggaaatcg gaaagcagat tcagttcttc ggcgcacgtg ccaaccttgc caaagccctg
     5281 ctactggcta tcaacggagg acgttgcgaa aatacaggta cagttatggt aaaagacatc
     5341 cctgtattga ccggtgaaac actgaagttc gaagaagtaa tggccaacta taagaaagta
     5401 ttgatacaaa ttgcacgtgt atacaacgaa gcaatgaata tcatacatta catgcacgat
     5461 aagtattact acgaaaaggc acagatggct ttcgtggaaa ctgatccccg cattaacctc
     5521 gcttatggtg tagccggact ttcaatcgcc atcgattcac tgtccgccat caaatatgca
     5581 catgtgaaag cccgtcgcaa cgacatcgga ctgacggagg gattcgatat cgaaggtgct
     5641 ttcccttgtt tcggtaatga cgatgaccgt gtagaccacc tgggtgtaga cctggtatat
     5701 ttctttagcg aagaattaaa gaaactcccc gtatataaga atgcccgtcc taccctctcg
     5761 ctgctgacta tcacttcgaa cgtaatgtat ggcaagaaga ccggtgccac tcctgacgga
     5821 cgcgccaaag gcattgcctt tgctcccggt gccaacccca tgcacggacg tgataaaaat
     5881 ggtgcaatcg cctcactgag ttctgtagcc aagttgcgtt atcgcgactc acaggatggt
     5941 atcagcaata cattctcgat cgttcccaaa tcattgggag caacacaaga ggaccgtatc
     6001 gacaatctgg tgaccatgat ggacggatat tttacaaaag gcgcacacca cctgaacgta
     6061 aacgtgctga accgggaaat gttgcaggat gcgatggaac atcccgaaaa gtatccgcaa
     6121 ctgactatcc gtgtctcagg atatgccgtt aatttcgtga aattgagccg cgaacatcag
     6181 ttggaagtaa tcagccgcag tttccacgaa agaatgtaat tgaatgataa acgtacactc
     6241 atacgagtca atgggaacat tcgacgggcc gggtctccgg ctcgtcgttt tccttcaagg
     6301 gtgtaacttc cgttgcctct attgtgccaa tccggacaca attgaagcca aaggagggac
     6361 agcaaccgat cctgaggaaa tagttcgcat ggccgtcagt cagaaagctt tcttcggtaa
     6421 aaagggaggt atcacctttt ccggcggaga gcctactttt caagcaaaat cgcttatccc
     6481 actttttaaa agactaaagg aagcaggaat ccatatttgc cttgatacca atggcgggct
     6541 atggaacaat gatgtagagg aactattgga attgactgat ctggttttat tagatatcaa
     6601 agaatttaat ccggaacatc atcagtcttt aaccggaaga agcaacgagc agaccctgaa
     6661 aaccgcagcc tggcttgaaa ccaatcataa accattctgg ttgcgatacg tattagtgcc
     6721 cggctacagt gacttcgaag acgatatccg gcagctggga gagcatcttg gaacgtacca
     6781 gatgattcag cgtgtagaaa tattgcctta ccacaccttg ggcgttcaca aatatgaagc
     6841 aatgaacaaa gaatatatgc tgaaaggagt gaaagagaat actccggagc agatagaaaa
     6901 ggctgagaaa ctattcaggc aatacttccg gaccgtacaa gtgaattgac ttatataagt
     6961 gtcgaaattc gtattcgcca cagattacac gaatttacac agataaagat tcattggcaa
     7021 tcaacagatt aagttcattc tgcggtgaat tatgacgact gcacttattt ataattttgt
     7081 aagtcacgat ataaaagtct ccctgttctt gccttaattc attacaatac aaggcaagaa
     7141 cagggagata atgtaaccgg catatttttt gccaccctac tttaataagt gaatcgcaat
     7201 cctgcctgca agttaaagtt acaaggcctt tcttttcgga tggtttgtac tttggagcca
     7261 tcatcaaaga aatacgaaac tcccggttcc acatataggc cgacatgatc tgtcgcattg
     7321 aattgcgctc ccacgacacc ggctacagaa aattgcaaag gcttcacatt caccttatca
     7381 tccgccaact ttccataaac acacttttca accattcctc cggcagatac atagagtgta
     7441 aaatatttct tttccagaaa attccagttt ccacgtacag gaatacctat ataatgcaat
     7501 ttctgactct gcatcttggt atccccctgc cgtttgatgt cagaagacaa caacgtataa
     7561 gtcaatcccg tctctacaga gaaacctttg ggaagagact tacgtacaga cagtccgaag
     7621 ctaaccggct gatgatgttc ataatccacc acggcagttg tattggactt caggtaaggg
     7681 actccttctt caaatataac ttcctgatcg gcaggaatac tcacagctcc attcatgatc
     7741 gtcatcaagt cgaccctgtt agtcatcgga cggggcgcaa aattttcgga accatttgtc
     7801 ggaagtccac ctccattacc gatacccact cccatcgacc atttaccacc acgtttagca
     7861 gaagagtctc cgataggcaa ctgatacttg tctttaccgg acggtcgccg cgcttctttc
     7921 ctctttggag gctgcgctgt cacactttct tttttctcga ttgccgcagt tgcttcctgt
     7981 tgcggctcag ctctcttttc ctccgtcact gcctccggtt gcttctctgc cagggaggat
     8041 acctccggaa caatcaccgg atcagtattc tttgccaaat agcccgaaac agggttaata
     8101 ctcgtcgttc ctaccggctt aacgggttcg gatacagcta cctgtacatc cggcaaggca
     8161 ggttccggca atacatccgg gttgacagcc agtgaaggag ccgttgcata acggatttca
     8221 tcagctaccg gactattcag aaaatacaaa ctgacagcag tcgttaccac caataccaca
     8281 gctgccgcag caaccgccca ccggcgatac ggatatattc gtttttcggt tacaggcatc
     8341 agttcccttt ccagtcgttc ccaaccggaa gcaggcatcg gctccgaata atcttcgagc
     8401 ttatccttga atgctttaat ccatttttcg tcttctttca tcattctatt tcatttttga
     8461 aatccaaggt tcacctcagt atctgtaaat acatgtcaac cattggtcac caaccattct
     8521 ttcactttct ttgccaatac actttttgcg cgaaaaagct gtgaggcaga agatttttca
     8581 ttaatcccca acatctgtgc gatttccttg tgcgacttat cttcaaaggt gtataaattg
     8641 aatacggtac gatatccggc ggggagttca ttaataaatt gcatcagcac tttctgtggt
     8701 attgcttcaa cagccgaagc atccggttct tcatacgttt cgggaacttc atccagtgcc
     8761 gtggtctggt tcatcacgtc gttctttctt aagaactgta aagccgtatt caccattaca
     8821 cgctccatcc atgctctcag agagccttca ccccgccagg taaacttgtc gaaggagtcg
     8881 aaaatcttca ggaaaccgtc gtgtaccaag tcttgtgcca tgtccctgtc tccggcataa
     8941 cgaagacaga caccaagcat gcgccctgcg tactgctcat aaagttcttt gcgggcacga
     9001 ttatctccct gcctgcaacg ttccgacagc tctaattcat tcattctcct aaacacgtgt
     9061 ttaccttata aatgcagcaa agatagaaat actgcacaga gagaacaact cttttatcac
     9121 ttttgtttct ttaacatttt aggatgcaat atttcatcac ttcctgcatt ttctcaatac
     9181 aataaagaat aaatctcaat ggataaatag gataaaacca acaagaaact tatgaagaaa
     9241 tttaatttaa taacttttgc cgtcatcctg atgttattgc ccattttaca gtcatgtctg
     9301 gacgatgcca acaacgacga gtgggtcact tgtcctccgg gtggaatatt ggccatcggc
     9361 acaatgaaga ttcccaatgc ggacactcca agggactttt tcattgcgtt ggacaatgga
     9421 gacaatgtac ttccggcaga tacggccgat atacgcaaca ggaaatacac tgttgcagaa
     9481 ggtcaaagag tcttcgttgg ctatctgcag atgggagaag agaaacccgg atatgagaac
     9541 ggtaaaatat tcacgataga agatatattg acgaaagaga tcatcccact gacggaagct
     9601 acagcagaca gcattggaga cgaccgtatc aacgtcacag cgcatgcact tacgaaagat
     9661 tatctgacca tcgaatatca atatctgggc agcatgaatg aaaataaaaa acacatgctg
     9721 aacttggtac aaaacgaaat aacaggtccc ataaaagatg acggatatat ctatctggag
     9781 ttccggcata atgcctttaa tgactccccc aatcaattgg gttcgagcct tgtttctttc
     9841 aagctggata gtatagccga gcaattggcg acagccaaag gaataaaact ccgtgtgaac
     9901 accatttatg acaatataca gtatgtcaca atagatatca acgaagacaa aaacttaaaa
     9961 ataaaatcat ttcattctca ataaaacaac aagaaacacc tacacaatca ggcaaaacga
    10021 gtaataattc tgatacataa aagaaataag gcggcgatgt ttgtgaaaat atcgccgtcg
    10081 tttttatatt ataccagaca ctgaacggcc tgcagggtaa gcatctcctt gggaaccgcc
    10141 gcctgaatct cctctttcaa aacctgcagc agactggtgc ggatgaagtc tttccgggtc
    10201 accaggacaa tctgacgggt aggccgcggg atagcaaacg gacggaccag ttctttctgc
    10261 tcttcgctca attgcatcac tgccagttcg ggaataaacg taatcccctt accactctcc
    10321 accatatgca taaaggtttc catactaccc agccgatacg ccatttggct gatcttaacc
    10381 gcttccatct gacaaaaacg aaccaactga tcgcggaagc aatgcccttc gtcaagaagc
    10441 caaagccgtt cccctgtcac atcggacgta cgaatcacat cgtgcttgaa caacggttcc
    10501 ttctttgaga catagcccag gaattgctcg tagaataagg tctcttccgt taatgcggca
    10561 tcatccagca tgctggcaat gatagcagca tccgcttcac cggtcagcag agccttgcga
    10621 atgtcgggcg tcttcatctc catcacccgt atatcaagat acgggtattt ctccatcagt
    10681 tgcggaaaga aacggggcag aagataaggt gcaatcgtcg gtaacactgc caatcggaat
    10741 gtacccgaca gggagtgctg ttcttcgctg atgatctcct tgacacagat aacttccgaa
    10801 agaatcttac gggcctgttc cagcactttc ttaccaatgg cagtagggca aaccggtgtc
    10861 atgctacggt cgaacagttt cacccccaat tcgtcttcca gcttctggat cattgcactc
    10921 aaagtaggtt gcgtcacccg gcaatactcg gcagctttag caaaatgccg gaactggtcg
    10981 acagccagaa tatattccaa ttgttgtata gtcatcgttc tctgatttat taaagatata
    11041 gaatctatca atgcaaagat agaaattttc agtttgacac gaatcatttt gtgccgtatc
    11101 tttgttccag ataaaaagaa gaaatatagt attaactcaa aaaaaacaat atcattatga
    11161 agactttaaa ttatacacat ttggaagaaa aaggagctaa caccatcgta ctgtcattac
    11221 agcaactgct tgccgatttt cagattcatt atgcaaacct gagaggattt cactggaaca
    11281 tcaaaggaca cggtttcttc gtactgcaca gcaagtttga agatttatat aacggagccg
    11341 ccgaaaaggt ggacgaaata gccgaacgta tactgatgct gggaggaact cccgccaata
    11401 aatacagtga ctatctgaag atggcgcaga tcaaggaagt ggacggagtg aataaggccg
    11461 acgacgctct gaatcatatt ctcgaaactt acgggcatct gattgcggaa gaacgtaaaa
    11521 tcctgtctct cgcctcttca cacaacgacg aagtaacagt ggccatgatg agcgactacc
    11581 tgaaagaaca ggaaaagatg gtttggatgc tgactgcata caacggataa cagccgaaag
    11641 ggtgtagcca tctgaccgaa aaggtgtagc catacaagca aaagggtgta gccatcccgg
    11701 cgggatagct acaccctttc tgttttattc gattcagatg atacttgtac gtttggtaaa
    11761 ttcaataatt tccggaatgt atccgaatgc gagcccggtc actgtatccg cacacccata
    11821 atagatggca atccgtccgg tctccgaatc atgaagcgct gcgcatggga aacagacatt
    11881 aggcacatca cccatacatt cgtaatcctt ctgaggtgaa atcagataag gccccgaacg
    11941 gaattttact ttccagggct gatcgatgtc aagcagtgcc gaaccaaaac tatacacaaa
    12001 accgttgcag gaagccaata caccatgata gatcagtaac cagccttccg aggtttcaat
    12061 cgggataggc cctgcaccga tcttggtaca ctgccaggca ctgtcttcga acggagccgg
    12121 cgacataaca tgacgatgac gtccccagaa ctccatatcg ggagactcgc tatagaaaat
    12181 atctccaaaa ggagtatgcc cattatcact cgggcggctc aacatcgcaa aacgaccgtt
    12241 tatcttacga gggaacaaga ctccattccg attgaaggga ataaaggcat tctccaactg
    12301 gtgaaaagta acaaaatcat aggtgtaggc cacaccgata gtaggaccat gatagccatt
    12361 acaccaggtc acatagtagc ggtcttcgat aaagcaaacc cgtggatcat atccatagac
    12421 ccaggttcca acctcagcgt catcacattg aaactttaac ggttcttcgt tgatatccca
    12481 atgaacagca tccttgctga atcccacatg caaacgcatg cgacgattag tatcatcaca
    12541 acggaacacc cctgcatagc catccttaaa cggaactacg gcactgttga atatactgtt
    12601 tgaagtaggg agcaagtcgc gcggaataat cggattggcc gaacaacgcc acactacatc
    12661 tttacatcct gccggacgtt cttcccaagg catagccggc aaagcagcac ctgcaatttt
    12721 aatttcttcc atgattcgat taaattaata ttatgtatat atc
//
