LOCUS       c00149_gnlPro..        13302 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPCEGDJH_149.
ACCESSION   c00149_gnlPro..
VERSION     c00149_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:04:42
            Original ID  :: gnl|Prokka|KPCEGDJH_149
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13302
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13302
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[343:3302]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      344..3302
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13302
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13302
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..131)
                     /locus_tag="ctg149_1"
                     /transl_table=11
                     /translation="LQRFKRKALLNRSSGEVAEWSIAAVLKTVVLRGTRGSNPCLSA"
     CDS             344..2572
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_2"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2577..3302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.8e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(3535..4797)
                     /locus_tag="ctg149_4"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(4849..5397)
                     /locus_tag="ctg149_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTVLQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5585..6337
                     /locus_tag="ctg149_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6442..7440)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg149_7"
                     /sec_met_domain="LysR_substrate (E-value: 6.6e-47,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.8e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7510..7983
                     /locus_tag="ctg149_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8087..9085)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 8.3e-70,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9140..10408)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg149_10"
                     /sec_met_domain="MFS_1 (E-value: 2.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10658..11671)
                     /locus_tag="ctg149_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEVET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11694..12830)
                     /locus_tag="ctg149_12"
                     /transl_table=11
                     /translation="MKRITIKQCLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 tcagcggaga gacagggatt cgaaccccgg gtacctcgca gtacaacggt tttcaagacc
       61 gccgcaatcg accactctgc cacctctcca gaactacggt taagtagtgc ttttctctta
      121 aagcgctgca aaggtacgaa tcatttttta acttgcaaat tattccgcaa aaaaatatta
      181 gaaaagtata tttggaagta ataaccgccc tctggcttct ccccataaat aggtattttt
      241 atgctattca acataaaata ggaccctttt atatacctaa accgaaaaaa ggttgtaaat
      301 ttgcgcgctc taaaggataa ctaaccacta actgattaat tttatggaac tgaataagac
      361 ctttaaagat ggactttgga gcaaagaaat caatgtaagg gatttcgtta gtaacaacat
      421 cactccttat gaaggggatg cttctttcct gcaaggacct accgaacgca ccaaagctgt
      481 ctggaatcac tgtctcaaag ctcttgaaga agagagaaac aataatggta ttcgtgcact
      541 cgactacaca actgtatcta ctataacctc tcaccctgcc ggctacatcg ataaagagaa
      601 cgaactgatc gtcggactac agaccgatca ggtgttaaaa cgtgccatca aaccgtttgg
      661 cggaatcaat gtggttatga aagcttgccg tgaaaacgga gtggaagtag atgacagagt
      721 caaggatatc ttcactcact atcgcaagac tcataatgat ggggtattcg atgtgtatac
      781 cgaagaaatt cgttcgttcc gttcattggg attccttacc ggacttcccg acaactatgc
      841 acgcggacgt atcatcggtg attatcgccg cctggctctc tatggtcttg accgtctgat
      901 agaagctaaa aaagaagatc tgcataatct gacaggtcct atgactgaag cccgcattcg
      961 tcttcgtgaa gaagtagccg agcaaatcaa ggccctgaaa gagattaaag tattgggcga
     1021 atattatggt ttggatctga gccgaccggc atataccgca caggaagctg tacaatgggt
     1081 gtatatggct tatctggctg ccgtaaaaga gcaggatggt gctgccatgt cactgggtaa
     1141 tgtatcttca ttcctcgaca tctatcttga atatgaatta agccagggta cgataaccga
     1201 aacattcgct caggaactga tcgaccaatt cgttatcaaa ctccgtatgg tacgccactt
     1261 gcgtatgcag tcgtacaacg atatttttgc gggtgatccc acatgggtga ccgaatctat
     1321 cggtggacgt ttcaatgatg gacgtaccaa agttactaaa acttctttcc gcttcttgca
     1381 gacactttat aacttaggcc catcaccgga acctaacatg actgtactat ggagccctga
     1441 gttacccgaa ggtttcaaag cattctgtgc acaagtatct atcgacactt cttccgtaca
     1501 atacgaaaac gacgacctga tgcgtgaagt ccgtcaatcg gatgactacg gaatcgcttg
     1561 ttgtgtttca tatcaggaaa tcggaaagca gattcagttc ttcggtgcac gtgccaacct
     1621 tgccaaagcc ctgctactgg ctatcaacgg aggacgttgc gaaaatacag gtacagttat
     1681 ggtaaaagac atccctgtat tgaccggtga aacactgaag ttcgaagaag taatggccaa
     1741 ctataagaaa gtattgatac aaattgcacg tgtatacaac gaagcaatga atatcataca
     1801 ttacatgcac gataagtatt actacgaaaa ggcgcagatg gctttcgtgg atactgatcc
     1861 ccgcattaac ctcgcttatg gtgtagccgg actttcaatc gccatcgatt cactgtccgc
     1921 catcaaatat gcacatgtga aagcccgtcg caacgacatc ggactgacgg agggattcga
     1981 tatcgaaggt gctttccctt gtttcggtaa tgacgatgac cgtgtagacc acttgggtgt
     2041 ggacctggta tatttcttta gcgaagaatt aaagaaactc cccgtatata agaatgcccg
     2101 tcctaccctt tcgctgctga ctatcacttc gaacgtaatg tatggcaaga agaccggtgc
     2161 cactcctgac ggacgcgcca aaggcattgc ctttgctccc ggtgccaacc ccatgcacgg
     2221 acgtgataaa aatggtgcaa tcgcctcact gagttctgta gccaagttgc gttatcgcga
     2281 ctcacaggat ggtatcagca atacattctc aatcgttccc aaatcattgg gagcaacaca
     2341 agaagaccgt atcgacaatc tggtgaccat gatggacgga tattttacaa aaggcgcaca
     2401 ccacctgaac gtaaacgtgc tgaaccggga aatgttgcag gatgcgatgg aacatcccga
     2461 aaagtatccg caactgacta tccgtgtctc aggatatgcc gttaatttcg tgaaattgag
     2521 ccgcgaacat cagttggaag taatcagccg cagtttccac gaaagaatgt aattgaatga
     2581 taaacgtaca ctcatacgag tcaatgggaa cattcgacgg gccgggtctc cggctcgtcg
     2641 ttttccttca agggtgtaac ttccgttgcc tctattgtgc caatccggac acaattgaag
     2701 ccaaaggagg gacagcaacc gaccctgagg aaatagttcg catggccgtc agtcagaaag
     2761 ctttcttcgg taaaaaggga ggtatcacct tttccggcgg agagcctact tttcaagcaa
     2821 aatcgcttat cccacttttt aaaagactaa aggaagcagg aatccatatt tgccttgata
     2881 ccaatggcgg gctatggaac aatgatgtag aggaactatt ggaattgact gatctggttt
     2941 tattagatat caaagaattt aatccggaac atcatcagtc tttaaccgga agaagcaacg
     3001 agcagaccct gaaaaccgca gcctggcttg aaaccaatca taaaccattc tggttgcgat
     3061 acgtattagt gcccggctac agtgacttcg aagacgatat ccggcagctg ggagagcatc
     3121 ttggaacgta ccagatgatt cagcgtgtag aaatattgcc ttaccacacc ttgggtgttc
     3181 acaaatatga agcaatgaac aaagaatata tgctgaaagg agtgaaagag aatactccag
     3241 agcagataga aaaggctgag aaactattca ggcaatattt ccagaccgta caagtaaatt
     3301 gacttatata agtgtcgaaa ctcgtattcg ccacagatta cacgaattta cacagataaa
     3361 gattcattgg ccatcaatag attaagttca ctctgcggtg aattatgacg actgcactta
     3421 tttataattt tgtaagtcac gatataaaag tctccctgtt cttgccttaa ttcattacaa
     3481 tacaaggcaa gaacagggag ataatgtaac cggcatattt tttgccaccc tactttaata
     3541 agtgaatcgc aatcctgcct gcaagttaaa gttacaaggc ctttcttttc ggatggtttg
     3601 tactttggag ccatcatcaa agaaatacga aactcccggt tccacatata ggccgacatg
     3661 atctgtcgca ttgaactgcg ctcccacggc accggctaca gaaaattgca aaggcttcac
     3721 attcacctta tcatccgcca actttccata aacacacttt tcaaccattc ctccggcaga
     3781 tacatagagt gtaaaatatt tcttttccag aaaattccag tttccacgta caggaatacc
     3841 tatataatgc aatttctgac tctgcatctt ggtatccccc tgccgtttga tatcagaaga
     3901 caacaacgta taagtcaatc ccgtctctac agagaaacct ttgggaagag acttacgtac
     3961 agacagtccg aagctaaccg gctgatgatg ttcataatcc accacggcag ttgtattgga
     4021 cttcaggtaa ggaacccctt cctcaaatat aacttcctga tcggcaggaa tactcacagc
     4081 tccattcatg atcgtcatca agtcgaccct gttagtcatc ggacggggcg caaaattttc
     4141 ggaaccattt gtcggaagtc cacctccatt accgataccc actcccatcg accatttacc
     4201 accacgttta gcagaagagt ctccgatagg caactgatac ttgtctttac cggacggtcg
     4261 ccgcgcttct ttcctctttg gaggctgcgc cgtcgcactt tcttttttct cgattgcagc
     4321 aattgcttcc tgttgcggct cagatctctt ttcctccgtc actgcctccg gtcgcttctc
     4381 taccagggag gatacctccg gaacaatcac cggatcagta ttctttgcca aatagcccga
     4441 aacagggtta atactcgtcg ttcctaccgg cttaactggt tcggatacag ctacctgtac
     4501 atccggcaag gcaggttccg gcaatacatc cgggttgaca gccagtgaag gagccgttgc
     4561 ataacggatt tcatcagcta ccggactatt cagaaaatac aaactgacag cagtcgttag
     4621 caccaatacc acagctgccg cagcaaccgc ccaccggcga tacggatata ttcgtttttc
     4681 ggttacaggc atcagttccc tttccagtcg ttcccaaccg gaagcaggca tcggctccga
     4741 ataatcttcg agcttatcct tgaatgcttt aatccatttt tcgtcttctt tcatcattct
     4801 atttcatttt tgaaatccaa ggttcacctc agtatctgta aatacatgtc aaccattggt
     4861 caccaaccat tctttcactt tctttgccaa tacacttttt gcgcgaaaaa gctgtgaggc
     4921 agaagatttt tcattaatcc ccaacatctg tgcgatttcc ttgtgcgact tatcttcaaa
     4981 ggtgtataaa ttgaatacgg tacgatatcc ggcggggagt tcattaataa attgcatcag
     5041 cactttctgt ggtattgctt caacagccga agcatccggt tcttcatacg tttcgggaac
     5101 ttcatccagt gccgtggtct ggttcatcac gtcgttcttt cttaagaact gtaaaaccgt
     5161 attcaccatt acacgctcca tccatgctct cagagagcct tcaccccgcc aggtaaactt
     5221 gtcgaaggag tcgaaaatct tcaggaaacc gtcgtgtacc aagtcttgtg ccatgtccct
     5281 gtctccggca taacgaagac agacaccaag catgcgccct gcgtactgct cataaagttc
     5341 tttgcgggca cgattatctc cctgcctgca acgttccgac agctctaatt cattcattct
     5401 cctaaacacg tgtttacctt ataaatgcag caaagataga aatactgcac agagagaaca
     5461 actcttttat cacttttgtt tctttaacat tttaggatgc aatatttcat cacttcctgc
     5521 attttctcaa tacaataaag aataaatctc aatggataaa taggataaaa ccaacaagaa
     5581 acttatgaag aaatttaatt taataacttt tgccgtcatc ctgatgttat tgcccatttt
     5641 acagtcatgt ctggacgatg ccaacaacga cgagtgggtc acttgtcctc cgggtggaat
     5701 attagccatc ggcacaatga agattcccaa tgcggacact ccaagggact ttttcattgc
     5761 gttggacaat ggagacaatg tacttccggc agatacggcc gatatacgca acaggaaata
     5821 cactgttgca gaaggtcaaa gagtcttcgt tggctatctg cagatgggaa aagagaagcc
     5881 cggatatgag aacggtaaaa tattcacgat agaagatata ttgacgaaag agatcattcc
     5941 actgacggaa gctacagcag acagcattgg agacgaccgt atcaacgtca cagcgcatgc
     6001 acttacgaaa gattatctga ccatcgaata tcaatatctg ggcagcatga atgaaaataa
     6061 aaaacacatg ctgaacttgg tacaaaacga aataacaggt cccataaaag atgacggata
     6121 tatctatctg gagttccggc ataatgcctt taatgactcc cccaatcaat tgggttcgag
     6181 ccttgtttct ttcaagctgg atagtatagc cgagcaattg gcgacagcca aaggaataaa
     6241 actccgtgtg aacaccattt atgacaatat acagtatgtc acaatagata tcaacgaaga
     6301 caaaaactta aaaataaaat catttcattc tcaataaaac aacaagaaac acctacacaa
     6361 tcaggcaaaa cgagtaataa ttctgataca taaaagaaat aaggcggcga tgtttgtgaa
     6421 aatatcgccg tcgtttttat attataccag acactgaacg gcctgcaggg taagcatctc
     6481 cttgggaacc gccgcctgaa tctcctcttt caaaacctgc agcagactgg tgcggatgaa
     6541 gtctttccgg gtcaccagga caatctgacg ggtaggccgc gggatagcaa acggacggac
     6601 cagttctttc tgctcttcgc tcaattgcat cactgccagt tcgggaataa acgtaatccc
     6661 cttaccactc tccaccatat gcataaaggt ttccatacta cccagccgat acgccatttg
     6721 gctgatctta accgcttcca tctgacaaaa acgaaccaac tgatcgcgga agcaatgccc
     6781 ttcgtcaaga agccaaagcc gttcccctgt cacatcggac gtacgaatca catcgtgctt
     6841 gaacaacggt tccttctttg agacatagcc caggaattgc tcgtagaata aggtctcttc
     6901 cgttaatgcg gcatcatcca gcatgctggc aatgatagca gcatccgctt caccggtcag
     6961 cagagccttg cgaatgtcgg gcgtcttcat ctccatcacc cgtatatcaa gatccgggta
     7021 tttctccatc agttgcggaa agaaacgggg cagaagataa ggtgcaatcg tcggtaacac
     7081 tgccaatcgg aatgtacccg acagggagtg ctgttcttcg ctgatgatct ccttgacaca
     7141 gataacttcc gaaagaatct tacgggcctg ttccagcact ttcttaccaa tggcagtagg
     7201 gcaaaccggt gtcatgctac ggtcgaacag tttcaccccc aattcgtctt ccagcttttg
     7261 gatcattgca ctcaaagtag gttgcgtcac ccggcaatac tcggcagctt tagcaaaatg
     7321 ccggaactgg tccacagcca gaatatattc caattgttgt atagtcatcg ttctctgatt
     7381 tattaaagat atagaatcta tcaatgcaaa gatagaaatt ttcagtttga cacgaatcat
     7441 tttgtgccgt atctttgttc cagataaaaa gaagaaatat agtattaact caaaaaaaac
     7501 aatatcatta tgaagacttt aaattataca catttggaag aaaaaggagc taacaccatc
     7561 gtactgtcat tacagcaact gcttgccgat tttcagattc attatgcaaa cctgagagga
     7621 tttcactgga acatcaaagg acacggtttc ttcgtactgc acagcaagtt tgaagattta
     7681 tataatggag ccgccgaaaa agtggacgaa atagccgaac gtatactgat gctgggagga
     7741 actcccgcca ataaatacag tgactatctg aagatggcgc agatcaagga agtggacgga
     7801 gtgaataagg ccgacgacgc tctgaatcat attctcgaaa cttacgggca tctgattgcg
     7861 gaagaacgta aaatcctgtc tctcgcctct tcacacaacg acgaagtaac agtggccatg
     7921 atgagcgact acctgaaaga acaggaaaag atggtttgga tgctgactgc atacaacgga
     7981 taacagccga aagggtgtag ccatctgacc gaaaaggtgt agccatacaa acaaaagggt
     8041 gtaggcatcc cggcgggata gctacaccct ttctgtttta ttcgattcag atgatacttg
     8101 tacgtttggt aaattcaata atctccggaa tgtatccgaa tgcgagcccg gtcactgtat
     8161 ccgcacaccc ataatagatg gcaatccgtc cggtctccga atcatgaagc gctgcgcatg
     8221 ggaaacagac attaggcaca tcacccatac attcgtaatc cttctgaggt gaaatcagat
     8281 aaggccccga acggaatttt actttccagg gctgatcgat gtcaagcagt gccgaaccaa
     8341 aactatacac aaaaccgttg caggaagcca atacaccatg atagatcagt aaccagcctt
     8401 ccgaggtttc aatcgggata ggccctgcac cgatcttggt acactgccag gcactgtctt
     8461 cgaacggagc cggcgacata acatgacgat gacgtcccca gaactccata tcgggagact
     8521 cgctatagaa aatatctcca aaaggagtat gcccattatc actcgggcgg ctcaacatcg
     8581 caaaacgacc gtttatctta cgagggaaca agactccatt ccgattgaaa ggaataaagg
     8641 cattctccaa ctggtgaaaa gtaacaaaat cataggtgta ggccacaccg atagtaggac
     8701 catgatagcc attacaccag gtcacatagt agcggtcttc gataaagcaa acccgtgggt
     8761 catatccata gacccaggtt ccaacctcag cgtcatcaca ttgaaacttt aacggttctt
     8821 cgttgatatc ccaatgaaca gcatccttgc tgaatcccac atgcaaacgc atgcgacgat
     8881 tagtatcatc acaacggaac acccctgcat agccatcctt aaacggaact acggcactgt
     8941 tgaatatact gtttgaagta gggagcaagt cgcgcggaat aatcggattg gccgaacaac
     9001 gccacactac atctttacat cctgccggac gttcttccca aggcatagcc ggcaaagcag
     9061 cacctgcaat tttaatttct tccatgattc gattaaatta atattatgta tatatcttgt
     9121 ttatattgaa aatctctttt tatttcttct ttccgtccgg atatgtgaaa ggtaccagcc
     9181 aagtcacgat aaaagccggt atggtagcga taagtaccca gataaagaaa tcgcgataac
     9241 ccagccaatc gctcaggtat ccgctcatca ttccgggaag catcaccccc agattcataa
     9301 taccggtagc aaaagcataa tgtgccatct gatgtttgcc gggagccact tgctgcatca
     9361 taaagagcat caatccgaca aaaccaaacc cgtaacccaa gtattcagac acaatggcca
     9421 taccaataat ccatagatcg gaaggctggt aaagggctaa caggaaatat accaagaacg
     9481 gaatattaaa agcgcaacat aaagaaaaca aagtcttccg aagtccgaaa gccgaaatgt
     9541 aataaccggc caaaagcgaa ccgagaataa aagctcccgc tccgaacgta ccatatacca
     9601 gtccgatatc ctgagtgctg agtcccaatc caccatccgc aaccgacgct ttcaggaaca
     9661 acggtacaat cttgatggca tatccttcgg caaaccggta caaaatgata aagacaatgt
     9721 agaaagcaat atgttttttt tggaaaaaag agcggatgac ttcccaaagc atattcaatg
     9781 cgtcactcat cgtattcact tcaccggaag cgcctcctcc cgaaggcaaa atccggatgt
     9841 ggtaaagacc gatcagaatc ataatacccg cacacatcaa catgacaatc atccaggcat
     9901 gtaccactcc aaattcatcc ttcagcatac ctgccaacca aaccaagcct ccgttggcaa
     9961 gtatcttggc cagattataa aaagctccct gccaaccgat atacttggct tgctgggtag
    10021 cagtcagttc agtcaggtat actccgtccc ccgcaatgtc atgagtcgca ccactgagag
    10081 caatgatccc catcagagcg atggcataac gaaaaaagtc gggcagcggc agcgaaagtg
    10141 ctaccaatgc aaatgccagt ccggtaataa tttccgtagc gacaacaaag tactttttcg
    10201 ttttaaacat ttccagaaac ggactccata aaggcttcaa tgtccaggga agcataatga
    10261 gagaagtcca gaaagcaatc tgtgcattcg acacttccat atcggaaaac ataaggacag
    10321 aaaccatcga aagggccaca aacggcaatc ccatagcaaa gtaaacagta ggcacccaac
    10381 atacagggct tatcggcttt ttattcatca gttagttttt tataataatt ccatcggtta
    10441 acaattccag taagcaaaga taggggatat taaaaacata acccaagatt acgacaagaa
    10501 gttgctttca ttatttaata atacaactca cccgggaaaa ctactaacct ctatcaccct
    10561 ttttttatta aactttatca atacgacaca cgcaaagaag caccgaagac tttcatcccc
    10621 gatgcctctc gcccccttat ctacaatcta aacacctcta ttgcttcaca tataaattta
    10681 tctcagcaaa cccggtataa ttatccggag tcagacagtt tattctgaat tcctttacat
    10741 tcgggatagg tggttcgatg gccgcatatt gcggatcagc ccctttaaaa tttctgaaag
    10801 tcaagactct cgggtaagta acccactcgg tttcaacctc tttccgaacc ttaatctcag
    10861 cacttctcag attataaccc gatccgtagg cactctgttt agtgaccgaa aatccggtta
    10921 aggtaacagg ccggtccagt accgtattcc accaacactc tccggcatta gccactcccc
    10981 atgtaaacca agtagtattt atctcaccgt caatagccag atgtgcacca tatttggcat
    11041 catcatcggc ataaacattg ctgcaactta cactccacgc acttcgatct acagcggacc
    11101 aattcccggg tttcgtataa ctggtataaa gcacgctggt ataaatccgg atataaaccg
    11161 tcttcataga tgtactgaca gcctgttcgt ccatgcccgt aactccttta agcgccacgg
    11221 gaagcacata tccgtcagga ttagtcaact tttctatatt cttcaaaacg acctgaaaag
    11281 atgaatcggc cactgtctgt cccgttttta agacaacttc acttgtttca atggtataat
    11341 tatcttgggg caacaactta catttcgtct tattggcaga attgtaagta tccactttca
    11401 gcgtatctac tcccaaagcg gcagtgacat cccgcgtaac cggctgtacg gcacacaatt
    11461 gtatttcaaa atcagaacgg tcggcagtag aggaattgct cacacaatcc accactaccg
    11521 cagcacccat ttcggccccc ggtgcaactc ccgttctgat atatatcttt tgatatttgt
    11581 ccatttcatc atcatcgttg ctgcacgaag ccaacgatac aaagcctgtt atcaggcaga
    11641 ttaaggtcac aaaattcaaa tgtctattca tatcttatct tctttttaca tagttattgc
    11701 ttatcaaaac gaacatgctc tttccagaca agagttcctc ctgccaccaa atcgtatccg
    11761 tgtccggtac agtcgacaaa ggcatttccc ttaccttcat ccattttcca atagcctatc
    11821 aggttcggat cggcgggctt cacggcaaaa tacatgttgg actgaatttg cgtctggctg
    11881 attgcgctct tccaaagacg cacctgggcc atctgacaat tgttgcggaa gtaactaccg
    11941 ctcgaaacca tgttcatctt gtcgaatcta accgggccac cctttgtctg cagagtcacg
    12001 tcgagcactc cgttgatata aatcgacaat aacccggaag aattataaac gaaggccaga
    12061 tgataccact tattcttctc aaacaaagtc accgtattga cctgacttcc aagtgtcttc
    12121 acctgtaatg aattataagg gatcatagcg tcaccgaaac ggatataaac ctcgtggtcg
    12181 ctgctgcccg aattaaatat agcctgatta ttaatatcga atccgtccat ctgtacccaa
    12241 gcctcgagtg accattcatt ggttgtcact ccccacaatt cgtccttggc gggcttcacg
    12301 gcattggtcg tattcataaa cggtacagac tgtatcagcg gcttatccag caaaatgata
    12361 aacttcgacg aaagcccgat tgtggacacc ggcccctgaa tttctgtgag agataccgga
    12421 atagcataca attctccgtt ttcgtttgaa taaggtttca ctctaaactc actggggatt
    12481 gcgctaacat cgcctgccgc tatctttatc tctttgtcat aagtaaaata ctgctcggga
    12541 aggacttcgt acgaagtttc attagcttca ttgtactctt taagaataga aggatctacc
    12601 gtcaggacag cagtcacatt ttcggttaca ggctgtccca cacgtacggt cagagtagtt
    12661 gttgttacat tttcaggatc aacggtaacc tttgccgaac cattctcgga tgcttcattc
    12721 aaataaatcg cattgtcgat aacctggtaa tcggcatcgt tgcatcctgc caggatcatc
    12781 ggcagaacga aacaggcaag caaacattgt tttattgtta ttcttttcat aatcaaattc
    12841 tttaaagtca ttttacagca ggattcatta ttctgattgc ttcacgcagg tacttatatt
    12901 cgatgtcgcc cggatagtca tattccatgt gataggtgcc tactccaccc ttccgtacct
    12961 gttttccgtc aatagtcgga gtccagcgtg ccatgccggc aagtgctctc attttgtttc
    13021 cgtaacgatc tacataatca cctcctcctg tcggagcata agattcgaaa ttctccgtaa
    13081 cgatgtacat attagccact ttctccggag gaagtattcc tttaaagttg gcaatcgtac
    13141 cagccagacg tctgtcaaga ttagcgtcgg aattacccgc aaggttagag tatgcctgca
    13201 caatgaaata gtcaaagtaa ggcccggttt ccggatgaat actttgaggc tcgccatcaa
    13261 tcacaagtaa ccgtcccgta cccgatttag gtccgattct tt
//
