LOCUS       c00084_gnlPro..        16491 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKCNNKHK_84.
ACCESSION   c00084_gnlPro..
VERSION     c00084_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:22:39
            Original ID  :: gnl|Prokka|AKCNNKHK_84
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16491
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16491
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2012:6491]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2013..6491
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16491
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16491
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             2..757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 8.2e-56, bitscore:
                     182.2, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="PVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKL
                     VTAMVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALAL
                     ARDTAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPEL
                     RNIICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRH
                     VIVVVLGCHPSRIWTESENLIRWALGYAV"
     CDS             816..1937
                     /locus_tag="ctg84_2"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVNPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVRDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             2013..3098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_3"
                     /sec_met_domain="GCV_T (E-value: 2.1e-87, bitscore: 285.9,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 1.9e-22, bitscore: 72.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGDSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRISAEGTDLIVCRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSQRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             3169..3549
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_4"
                     /sec_met_domain="GCV_H (E-value: 2.4e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             3645..6491
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 4.2e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 2e-178, bitscore: 586.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIKNKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             6847..7812
                     /locus_tag="ctg84_6"
                     /transl_table=11
                     /translation="MIFHHVFGLYALPAGVDTAWIAPQLTKAAPIFKICVPIFIFITGY
                     AMGWKTNSSPTFGSLIKTGFSHYFKFWKIYFLCLLLAILVSWAFPLPILPSVADMGWKN
                     GLLVVTGLRPCYPDWWYMALFAAATMALYPICAWITHHIAPVPSMAALLGVSLLLQSTA
                     HIPSLPGIAYSFPPFLPCFILGYMCAFLASRLSALSISQSLGAILLLVLEILSIHLFSF
                     SKAKTLTVIFLFTLWCLPWITRKLRLTPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGT
                     QSISVVFIVTLVSSLLLAMAMQKLFNRMIPSNPQTQSKTL"
     CDS             complement(7844..8476)
                     /locus_tag="ctg84_7"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPSMTVMDDDGEPSVLPDPGSEPGGADSGWSRKKYWIRVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGFFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8485..10593)
                     /locus_tag="ctg84_8"
                     /transl_table=11
                     /translation="MGASGQATKPAARSVKTSKPNVIFILVDDMGWGDLDSNWSQQKLN
                     GRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASLLLGVHQGNSRVVRNNRF
                     DQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAGPHQRGFNYFYGILDHLA
                     GHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFAARAKQWIVDQRKFARKT
                     GKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGTESVNTAFDAKAEKNKDT
                     YIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDDNTMIVFSSDNGPHNEGG
                     ADSRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWPARIPKGQISLHPGQFHD
                     WLATLADVAGVPVPARSDGVSLLPTLTGHADQQKPGIVYAEYNFAGKTPEYKDFLGEHK
                     GAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESKDLASSKPELQARMKAAA
                     LSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFPWVPDFRQWKKPASAHGV
                     TPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGSKAFVRLHGMELIDADKT
                     YEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLVLKWEGPGLSKKEIPASA
                     FSHGKESR"
     CDS             complement(11063..12919)
                     /locus_tag="ctg84_9"
                     /transl_table=11
                     /translation="MFSFFRDFDRSFFPMTQTSSFSALGISPEILEAIEVLGFDTPSSI
                     QEQAIPAAISGADIVGLSHTGSGKTLAFAIPALECIEPEERCVQVLALCPTRELAVQIC
                     REVDKLALFMDGVSAVPIYGGASFRPQLDALRRGVQFVVGTPGRVMDLMESGALRLDGL
                     RMLILDEADEMLDMGFLEDIERIAEAMPETKQTLFFSATMSPEINRLVSRFMKEPIQIS
                     IERPTLTVPTIEQVYYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVDGLTAR
                     GYPVDRLHGDMPQMMRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFELPRDPE
                     DYVHRIGRTARAGRKGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQLRTES
                     LVDDILERLKPDAVLPEELKEVEAAPEAMAAALFDLLRERTHREVQPIPEDKPARRARR
                     MPQTGEEAESPQKGDSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKGAVGDI
                     RIFPKHSLIEVDASVAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRNGGFRN
                     SYRGERDRSDRSGFRGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             13069..13872
                     /locus_tag="ctg84_10"
                     /transl_table=11
                     /translation="MIQIFPSEFMDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANP
                     LERPEGENFWHIGPVWALVIALSLPLVYGIRSLVVSRKFDLMSVVGMAGVLLTGVISIF
                     VIGPEGRIHSATPWLFAGKEALIPLILAAAVVVSRSAGTPLLNMFIYTPELFDVRRIEQ
                     TVAANGEERAYQKLLANSSWILAGTLVASSIGNFFLSLSFMSSVIQQPEAEQQVAYNAA
                     IGSITWWGFLIIGIPILAALVFIMTRLIKRLGRLTGLSRDELLLK"
     CDS             13883..15421
                     /locus_tag="ctg84_11"
                     /transl_table=11
                     /translation="MRLHTSCILAAAIALHAAWADTPRFDRVFGSHMVLPHGKNIPVSG
                     TAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCATGQTLAAVQNGDSAKLEDVLV
                     GEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNVPQAHTNNAPYSAKDFDAVT
                     TDNFYKGQWAASSPATSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGSEIAAWIPRQV
                     INANNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPAFLYESGIAWT
                     TALPITGVIWYQGESDAEIIDNAQNSMLLKTMISSWRKAFRNPEMPFVMIQLPRINDPS
                     KIRAGWPEFREMQDAVAKTVPKVYSVNTIDLGSTNSDVHPPFKRPVGERAGNTALNKVY
                     GKKIPCEGPALKAFKPSGSNILVQLDQAAGLTTTDGKEPAQFEIAGTDGTYHPAAAEII
                     NRKGNTAVIRLSSPEVKSPKHARYCWNRFVTPNLVNGNQLPARPFRTDEPVLKK"
     CDS             15443..16420
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg84_12"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 3.9e-26, bitscore:
                     85.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLILASLTATLSLGIAAQAAPAKVACVGDSITFGTGLKPGET
                     RYPQVLATLMGPDFDVRGFGNPGKTAGDYPGQAGRWYGSTREHKQALEFKADIYICNLG
                     INDTGRWWNPELFSKGYDALLHAWKNANPKTRFFAWGLLGPDYRGPLNKKAFPGNCYPD
                     VRKYAGSDNGSSANRPEAEKLIAAVARKYKVSLFDALHPLSDHPEWYVDGLHPTEQGAR
                     RIAEITFAKLAKSLRLKQPAPRLEPGTGNVIINNPGNSGILLDGWKLTDGTNTLIFENS
                     TVIHPKDRLIIAIGPETQKDPTKPLQIKSSQSPAAFRLIPAKKY"
ORIGIN
        1 ccctgtagcc atcccctcaa gcgccccgcg cacgccccgc tgcgccagtg cctgcgtcat
       61 ggacgccctt accggcaaag tgctcttttc ccacaacggc ctccagcacc gccaggtagc
      121 cagcacgcag aaactcgtga cagccatggt cgtgatggaa cacggcagcc tggacaaaaa
      181 agtggtcatc cagccttccg ataccaaggc ggaccccacc aaactgggat tccgggcggg
      241 ggaagtctat tcacgccgcg aactgctcaa tgccatgatg atccgcagtt tcaacgacgt
      301 agccctggcg ctggcccgcg atacggcggg ttccgttccc cgtttcgccc agttgatgaa
      361 tgccaaagcc cggcagatgg gcatgtacaa ctcacgcttc gccaatccca acggcctccc
      421 ggcagatcaa tattccactg ccattgacat ggcccgctgc gcctattacg tgtaccgcaa
      481 cccggaactg cgcaatatta tctgcaaacg ccaatatgcc tttacccgcg ccaacggcag
      541 aacgcttctg ttgagaaaca ccaacaagct gctcacccag aacccctggg ttaccgggat
      601 gaaaactgga tacacgaacg ccgccggacg ctgcctggtt tcctcagccg gcgtcaacgg
      661 gcgccatgtc atcgtcgtcg tcctcggctg ccatccgtcc cgtatctgga cggaatcgga
      721 aaacctgatc agatgggctc tgggatacgc cgtataaatg cccgtcggca attggtattt
      781 gactttcacg gcgtgacccg ctatcagtcc tgcctatgtt acaggcaggt attgtaggtc
      841 tccccaacgt cggcaaatcc actctattca atgcggtcac ccggacgcgc aaggcccagg
      901 cggccaacta tcccttctgc accattgacc cgaacgtggg tatggtaaca gtcccggatc
      961 cccgcctgca ggttctttcc gacatgtccg gttctgaaaa aatcatcccc acgcttattg
     1021 aattcgtgga tattgccggc ctggtcaagg gcgcctcgga aggcgccggc ctgggcaacc
     1081 agtttctggc gaacattcgt gaagtggacg ccatcgtgca ggtagtccgc tgctttgaca
     1141 atgatgatat cattcatgaa ctcggttccg tgaatcctct gcgcgacatt gacatcatca
     1201 actcggaact cattctggcg gatatcgcca ccatggaaaa gagactctct tcccgcgaac
     1261 gcaaggcacg cagcggcgac aaggaagcca aggccgaagt ggccctcatc accaaactcc
     1321 tgccccacct gaacgaaggc aatcccgccc tcacccttga accgcagctg gacgacgatg
     1381 aacgcaagct gctccattcc ttccagctgc tttcggataa aaaaagcatt ttcgcctgca
     1441 atgtcaatga agacgaactg gcggacgcca tctccaaccc ggacgcccat ccctacgtct
     1501 cccaggtgaa aaaatacgta gcggaacacc acaacgcgga agccattgtc atctctgccc
     1561 ggattgaaga ggaactcatc gacgtctcgg aggaagaatc ccgcgaattt ctggaatccc
     1621 tgggcgtgcg ggattccggc gtttccgacc tcatccgggc cgtgtaccac cttctgggcc
     1681 tgcgcaccta cctcaccacg ggaatcaagg aaacgcgggc ctggaccatt ccgtccgggg
     1741 caaaagcacc tcaggcggcc ggcgttatcc acacggactt tgaacgcggt tttatcgccg
     1801 cagaggtagt gcactacgac gacctggttt cctgtggcgg caaggccgga gcgagggaac
     1861 acggcaagct gcgcatcgaa ggaaaagaat atgtcgtcaa agacggggac gttatcgaat
     1921 tccgcttcaa tgtctagacg gaagcgttac cggaattcca ttgactttta ctgatataag
     1981 gagcagattg ctcacaacct tcacatcgcc tcatgactga tacagacgtc aaatccaccc
     2041 ccctggcagc taaacacgtt gaactgggag ccagaatggt tccttttgcc ggctggaata
     2101 tgccggtgca gtacaccggc attctggacg aacacaaagc agtgcgcgaa acctgcggca
     2161 tctttgacat ctcccacatg gggcagttca cggtagccgg cgattctgcc gcggcctggc
     2221 tgaactccat gctgaccaat gacatcaaca aattgaatgt agggcagggg caatactccg
     2281 tcatgctcaa tgacagagcc ggagtcattg acgaccttat cctgtaccgg atggaaccgg
     2341 aaaccttctt cgtagtggtg aacgcctcca agattgatga agacttcgca tggctttccg
     2401 cccatcaacc tgcaggcgta accctggaaa accactccga cgaatacgtg gggctggctg
     2461 ttcaaggtcc cgaatgcgga gaagtattct cccgcgtcat ccccggtgtg gaacttcccc
     2521 cccgcaatgg aatttcccgc atctcggcgg aagggacgga tctcattgtc tgccgcaccg
     2581 gctataccgg ggaagatggt tttgaattct tctgcccggc taaggaaggc gtcaaatggt
     2641 ttgaagcctt tcttggagca ggagccaaac cctgcggcct gggcgcccgc gacagtctgc
     2701 gtctggaaat gtgctatcct ctgaacggct ccgacctctc tccggacaag acgcctctgg
     2761 aagccgggct cggcttcttc tgcgcgctgg atacggattt catcggttcc gatatcctcc
     2821 gggaacaaaa agccaacggt ctcagccagc ggctggcggc tattgaatac accggcaagg
     2881 gagcccctcc ccgcgcccat tatgccgttc acgtccccgg cggagaagcc atcggagaac
     2941 ttaccagcgg cgtgctctct ccttcgctga tgaagggtat tgccctggcc tacctgcctg
     3001 ccgcccatgc caaggtcggc acggagctgg aaattgacgt aaggggaagg aaatttccgg
     3061 ccgtggtcgt aaaaaaaccc ttttataaaa aaggctgaca cgacggcgca aaaataaact
     3121 gacaaacacc tcattttact acactctcac ttcaaacaat tacatcttat gcacgacgta
     3181 ccagaaaatc tgctgtattc caaggatcac gaatggattg aaattgacgg ggacatcggc
     3241 accatcggca tttcagacca tgcccaggcc gaactctccg atgtcgtctt tgtagacctt
     3301 cccgaagtag gcgccaccgt cgcggccggc gaccccgtcg ccgtcgtgga atctgtcaaa
     3361 gccgccagcg acgtgtacac ccccgtttca ggagaaatcc tggaagtgaa tgaagagctt
     3421 tccaatgacc cctccctcat taactccgac ccctacggcg caggctggct gtacaaaatc
     3481 cgcctggacg ttcccacgga aacggaagat atgatgaacg ccacggatta cgaggaatac
     3541 tgctcctgaa ccattctttc ctcccccgcc ccggtgattc catcccgggg cattttgttt
     3601 ggcccgtccc gcggccggac gctattacca gccagagata ccacatgaat acccactcag
     3661 attttgccag ccggcacatc ggcccccagg gggaagaacg ccgggaaatg cttgacagcc
     3721 tcggctaccg gacgcttgac gaactcattg cggacatcgt ccccgcagat atccgcatga
     3781 aggccccgct ggacctgccc gcagccaaat cggaaacgga agccctggag gaactccgtt
     3841 ccattctgcg gaaaaacaag ctcctgaaaa ccttcattgg ccagggctat tacggcacca
     3901 tcactccctc cgtcatcctc cgcaatgtac tggagaaccc cggctggtac acggcctaca
     3961 ccccttatca accggaaatc gcccagggac ggctggaaat gctcatgaat ttccagacca
     4021 tggtctcttc cctgacaggg ctgccggtag cgaacgcctc cctgctggat gaaggcaccg
     4081 cagcagcaga agccgtcacc atgtgccgga acgcgcgccc caaagcaaac accttctttg
     4141 tggcggacac ctgccatccc cagaccatca gcgtcatccg tacccgcgcc gccttccagg
     4201 gcgttaacat catcgtggga gattgctcat cctttgaccc cgcatccatc ggtgcggatc
     4261 tggccggagt gcttgtccaa tatccggaca cgctcggccg catctgcgac tacacggact
     4321 tcttttcccg cgtgcatgcc acgggcgcgc tctgcgtcgt ggcggcggat ctcatggccc
     4381 ttaccgtcat ccgggaaccc ggcgccttcg gagccgatat ctgcatcggc aacacgcagc
     4441 gcttcggcat cccaatgggc ttcggcggcc cccatgccgc ctacatgtcc tgcacggacg
     4501 ctctcaaacg ccgcatgccc ggccgcctta tcggcatgtc catagatacc ctgggccgcc
     4561 cggcctaccg cctggccctg caaacgaggg aacagcatat tcgccgcgac aaggcgacct
     4621 ccaacatctg caccgcccag gtgctcctgg ccgtgcttgc cgccttttac gccgtatacc
     4681 acggacagga aggcctcaaa cgcatcggca cggaaatcca cttgaaaacc aaaagcctgt
     4741 acaaggcgct cacggaagcc ggcatcgcca ttaaaaacaa aaacttcttt gacaccctgc
     4801 tgctgtccgt tcccggacaa gcggacgcca tggtgcaaaa agccctggaa gccgggtaca
     4861 acatccgcag ggtggatgcc gaccacgcag ccatctctct ggatgaaacc gcaacctgtg
     4921 cggatatagc ggcactggcc tccgcccttg caggtgcgga aacatccgct gcctgcgatt
     4981 gcgacgctcc tgcctgggat cccgtccaca cgcgccagac gcctttctgc acggaaaagg
     5041 ctttcaactc ctaccattcc gaaacggaaa tgatgcgcta catccgccgc ctggaatccc
     5101 gggacctggc tctaaatgaa gccatgatcc ctctgggctc ctgcacgatg aagctgaacg
     5161 ccgcctctga aatgattccc atcacgtggc cggaagccaa ctccctgcat ccctttgttc
     5221 cggcggacca gtcggaaggc atccgggaaa tgctctccgt cctgtccgac cgtctggcga
     5281 aaatcaccgg ctttgccgcc gtatccctcc agcccaacgc cggcgccgca ggggaatatg
     5341 ccgggctact ggccatccgc cgctaccaga agcacgccgg agaaggccac cgcaatgtct
     5401 gcctcattcc cacctccgcc cacggaacaa atcccgcatc ctccgccatg gccggcctca
     5461 aggtggtgcc cgtcaaatgc gacgaaagag gcaacatcga catggcagac ctgaaatccc
     5521 aggcggaagc ccataaggac aatctctcct gcatcatggt cacgtacccc tccacgcacg
     5581 gggtatatga acagacaatc aaggaactct gcgacatcgt ccatgccaat ggcggccagg
     5641 tgtacatgga cggcgccaac atgaatgccc aggtaggtct gacttgcccc ggctgcattg
     5701 gcgcggacgt ctgccacctg aacctgcata aaacctttgc catgccgcac ggcggcggcg
     5761 gtcccggcat cgggcccatc ggcgtagcgg aacacctcgt acccttcctg cccgggcacc
     5821 tcacgctggg ccatgaagaa ggggccgtag cgtctgcggc gtggggaagc gcctccatcg
     5881 ccgccatctg ctggatgtac ctctccatga tggggccgga cggcctcagg gaagccacgg
     5941 aaatggccat ccttaacgcc aactacattg ccaagaaact cggacatctc ttcccggttc
     6001 tctactccgg caacaagggg ctggtggcgc atgaatgcat tctggatccg cgtcagctca
     6061 ctcatgacgc cggcctcacg gtggatgaca ttgccaaaag gctcatggac tacggcttcc
     6121 acggccccac catgtccttc cccgttccgg gcaccctgat ggtggagccg acggaatcgg
     6181 aacccaaaaa agaactggac cgcttcattg aagccatgga acgcattcat gcggaaatca
     6241 cggccattat caacggtacg gcagacaagg aagacaacgt cctgaaaaac tcgccccata
     6301 ccgcagaaat ggtctccgcc gacgaatggc ggcaccccta ctcccgcagt gaagcggctt
     6361 atccggtctc cggtctcctt attcacaaat tctggccgta tgtaggccgg gtggataatg
     6421 tgtacggaga ccgcaatctg gtctgcacct gcgacacggt ggaggaattc tccaaggccg
     6481 tagagttata aaaatctcat ccttcctttc aaaaaggctg ttccattcat ttggagcagc
     6541 ctttttctta tgttcaagaa tcggatttcc aatccgaaag agcaaacata tccagaaaac
     6601 aattaagccc aaaagcaata tgggttgaaa aagaaaaaag gaacatttct cccaccccgc
     6661 ttttcctccc ctttcatttt gatgacccat ttgttctcaa aatagagtgt tgacttcgga
     6721 ttggaaatcc gttgagctac gtctcagatg agctttttct ctgcccttac tgttcctggc
     6781 cttcaacagc atctttcttt ttccagggaa gattccgcta tcctcaaagg gtatggaatt
     6841 ctcttcatga tctttcatca tgtcttcggc ttatacgctc tacccgcagg tgtggatacg
     6901 gcatggattg ctccccagct taccaaagcc gctcccatct ttaaaatttg cgtgcccatt
     6961 tttattttca tcacggggta cgctatggga tggaaaacaa attcatcccc aaccttcggt
     7021 tccctcatta aaacaggctt ttcccattac tttaaattct ggaaaattta tttcttatgc
     7081 ctccttctgg ctattctggt ttcctgggca ttccccttgc ccattttgcc atccgttgcc
     7141 gacatgggtt ggaaaaatgg cctgcttgtc gtaacaggat tgaggccctg ttatcccgac
     7201 tggtggtaca tggctctttt cgcggcagcc accatggccc tttatccaat ctgtgcgtgg
     7261 atcacgcatc acattgcgcc tgtcccgtcc atggcagctc tgctgggagt gtctctttta
     7321 cttcaaagta cggctcacat tcccagcctg ccgggaatcg cctattcctt ccctcctttc
     7381 ctgccctgct tcattcttgg ctacatgtgc gcctttctgg cttcacgcct ctctgctctt
     7441 tcaatttccc aaagcctggg ggcaatcctg ttgctggttc ttgaaatact atccatccat
     7501 ctcttcagtt tttcaaaagc caaaaccctg acggttatct ttctcttcac cctctggtgt
     7561 ctgccttgga taacccggaa actccgcctc acaccgctct tgacgctgct gggaacttat
     7621 tccgcactta tgtggctgaa tcacagattc attttcggct accacttcag ctgggacctc
     7681 tatggaaccc aaagcatcag cgtagtattc atcgtgacgc tggtctcctc ccttctgctg
     7741 gccatggcca tgcaaaaact ttttaaccgg atgattccct caaatccgca aacgcagtca
     7801 aaaactttgt agcaacttta caaggtccgg attccaacac ctcttaattc caagggggat
     7861 ctccgtactt attttctcca atccggcttt ccccatggga taaataccac aacagcagcc
     7921 accctatgaa gggaacggcc agaaaaacca ggaaaaagcc gctcctcccg acatcatgca
     7981 gacgccggac catggtagcc gccagcggaa tagacagcac ggcgagcacc acgtacagca
     8041 gaggggaaac cagctcaacc cacggaacca gggacgggaa aaaaccgcat tccgcaaaag
     8101 aggggactcc cgccacggcc agccacgcaa cccccactct ggaaaaaacc tcgtgcagct
     8161 cccctttccc ggcacggccc tcaaaacggc accatgcctt gatgacgcgt atccagtact
     8221 tcttcctgct ccagccggag tcggcgcctc caggctctga accgggatcc ggcagaacgg
     8281 agggctcccc atcatcatcc ataacagtca tggaggggat aaaagaggcc agaggcctcc
     8341 agtctccgcc gggaaccttc cggaccaaag tccggttgga caggcggccg aggttacggg
     8401 cccgcagcaa aagcaccagg tcaaccgggc ctttggaaga accgtcaatt gcctgatact
     8461 cgtacagatc gctcatgggg atgcttacct ggattccttc ccgtggctga aggcggaggc
     8521 gggaatctcc ttcttggaca aaccgggacc ttcccacttc aaaaccagtt tggaggcagt
     8581 accggagttc cccacatagc caatgcggat gggatgaagt ccagctttca aataaacggg
     8641 attcttccgg tcacccagat cggaggagac ctcggccccc ggctcataag ttttgtccgc
     8701 gtcaatcaat tccatgccgt gcagacggac aaaagccttg ctgcccttat tttcatccgt
     8761 ggtcagataa aacgtatatg ctccgtcctc tggaatcttc acatatcccg tcagctccac
     8821 accgcgcttg tccgaaccgt tcattttcac ggatggggaa ggcgtcacgc catgggcgga
     8881 agcaggcttc ttccactggc ggaaatccgg tacccaggga aaatccccct catacaaggc
     8941 ccatcgcaac ccgggagaaa cggttccctt cacatccacg gcaggcacca gcgcagaatc
     9001 aaacactgtt ttggaaggaa gggaagcccg gcgattggac aaagcggcgg ctttcatgcg
     9061 ggcctgaagt tccggcttgg aggatgcgag atctttgctt tcctgcggat cattcaaagt
     9121 atcaaaaatc atgaaatcct tgtccgcatc cttcaccccc atgcgcaagc ctttcaatcc
     9181 atccacaaaa acaatctgct gctggcctcg ctgcgctccc ttgtgttcgc ccaggaaatc
     9241 cttatactcc ggcgttttgc cggcgaaatt atattcggca taaacaatgc cgggcttctg
     9301 ctggtccgca tgaccggtca gcgtcggcag cagggaaacg ccgtcactgc gggctggaac
     9361 cggcaccccg gcgacatccg ccagcgtagc cagccagtca tggaactgtc caggatgcag
     9421 gctgatctgc cctttgggaa tgcgggcggg ccagcgtacc agcgtaggca cgcgcatgcc
     9481 tccttcccag caatcgcgct taataccgtc catcatgcca taactcttga aaaactgcgg
     9541 attttgcgct ccgtgccagt gcctggagtc ggcgccaccc tcattgtggg ggccattgtc
     9601 ggacgagaaa acgatcatcg tattatcgtc aatcttcaaa tctttcagca gacggatcaa
     9661 atcagccacg gcatcgtcca cgcggcggat catggtggaa tgacgtttgg ccacatcatt
     9721 cgggaaacgg gaattgtccg gatgaatata ggtatcctta ttcttttccg ccttggcgtc
     9781 aaaagccgta ttcacggatt ccgtgccttc cttctttacc cattgcaggc ctcctttcaa
     9841 tccgccgccg gaaggatagg gaacccccgg aaccaccaga ttgccgtggg gcgccggaaa
     9901 agccaggtac aggaaaaacg gctttccggt cttgcgggcg aacttgcgct ggtccacaat
     9961 ccactgcttg gcgcgggcgg caaataaatc cgtggaataa gccgtctggg gcacctggtc
    10021 cttgatattt ttccactcgg gattggaagc gtaaccgttg tattcgaaaa cgtcacggga
    10081 ttcggaagga tagtgaaaat gccctgccaa atggtccagg ataccgtaaa aataattgaa
    10141 tccccgctga tgggggccgg cggtcatggg cacatggctc tggcctccgc cgcctacacc
    10201 ccatttgcca atggcggcag tatcataccc ggcatcacgc atcacggtac ccagcgtatg
    10261 ggaatcttca ataggctggt cgaaacggtt gtttctcacc acgcgggaat tcccctggtg
    10321 cacccccagc agcagggagg cgcgcgccgg agcgcaaacc ggagcggcgg aataatgacg
    10381 gcgcagctga atcccctccc gagccagagc ggacagggca ggagtcttga actcgttctt
    10441 tctctccacc gtccggccat tcagcttctg ctggctccag ttggaatcca gatcacccca
    10501 gcccatgtcg tccaccagaa tgaaaataac attgggtttt gaagttttga cagaccgggc
    10561 agccggcttc gttgcctgcc cggaagcacc catgcacgga accagggaag tcagaagaac
    10621 ggatagtaaa gataccagct tcatgattca aagaaaatag actctaaaaa agacgttaaa
    10681 ataaagcgtt atcttacatg aattttctca tccctcaaga aaattacgag gaaagggcac
    10741 agaggattga atcgccagta ttatcggcaa aaaacatcag ggaaccagcc ttcacagccg
    10801 gaacaactac aacccgccat actgcaccaa tgagcggctt ttctggctga agccaggaat
    10861 gggagaaaat tcctcctgca ttcccggcgc cccggtcacc agccccgccc ggccatgctt
    10921 tatcctgaat aaaacggcaa tccccccgcc gggcagaaaa tacagaaacc ggcggaaaca
    10981 gcaatcatga accggaacgt tccaaaatgt ccgcgccaat tccggaacag cgttaataac
    11041 cctgtccgga atagcgaagg catcagaaac gcttcttcct gtcgtccctg cgggaacgtt
    11101 cgccccagcg ttcgccgcgg tcactgcgga agcccccgcg gtttcccctg aatccgctcc
    11161 ggtcactgcg gtcccgctct ccgcggtaac tgttgcggaa tcctccattg cggcgggaag
    11221 agcgcggagt tccggaatat tccggagccc ccttgtcttc acggacatta acttcatagc
    11281 cgcagacggt agccgtcgcc agggcctcca gaagcagggg cgccacggaa gcgtccactt
    11341 ctatcaggga atgcttgggg aaaatccgga tatcgcccac ggctcccttt tccatttcca
    11401 ccgtattgta aaataacccg gctatgtctt tgggccgcaa gccaatcatc cggcctccat
    11461 tcataaacag cgtaaccgta tcccccttat gctgccagga atcacccttc tgcgggctct
    11521 ccgcctcctc cccggtctgc ggcatacgcc gcgccctgcg ggcgggcttg tcttccggaa
    11581 tgggctgcac ttcccggtgc gtacgttccc ggagcaagtc aaacagggcc gcagccatgg
    11641 cctccggcgc agcctccact tccttcaatt cctccggcag cacggcatcc ggcttgagac
    11701 gttccaggat atcatccacc agggactctg tccggagctg gtccacctga acggcagtca
    11761 acacaggttc cggagtcaac ttaacgccga tgaaacgttc aatgcggctc atcagggaaa
    11821 aatcacggcg ccccacaaaa gtgatggcct tccccttgcg gccggcgcgt gccgtgcggc
    11881 cgatgcggtg cacgtaatcc tccggatcac gcggcaattc aaaattcacc acggcatcca
    11941 catcgtccac atccaggccg cgagcggcaa tatccgtcgc caccagaagg cgcaggctcc
    12001 ccttgcggaa ggaatccatc acgcgctccc tcatcatctg gggcatatcc ccatgaaggc
    12061 gatccaccgg ataaccgcgg gccgtcagac cgtccaccac gtcatccacc acctttttgg
    12121 tattggcgaa caccagcccc attttaatct ttccggtgtc aagcagccgg ctgagtacct
    12181 caatccggga ggaaaacacc acttcgtaat aaacctgttc aatggtaggc accgtcagcg
    12241 taggccgttc aatggaaatc tggatgggct ccttcatgaa cctgctcacc agacggttga
    12301 tttccggaga catggtagcg gaaaaaaaca gggtctgctt cgtttccggc atggcctccg
    12361 caatgcgttc gatgtcttcc agaaaaccca tatccagcat ctcgtccgcc tcatccagaa
    12421 tcagcatgcg gagtccgtcc agccttaatg cccccgactc catcagatcc atgacgcgtc
    12481 cgggcgtccc caccacaaac tgcaccccgc ggcgcagggc gtccagttgc ggacggaaag
    12541 aagccccccc gtaaatgggg acggcggaaa cgccgtccat aaataaagca agcttgtcca
    12601 cctcccggca aatctgaacg gccagttccc gagtaggaca aagagccagc acctgaacgc
    12661 agcgttcctc aggctcaatg cactccaggg ccggaatggc gaaggcaagc gtttttccgg
    12721 aacccgtatg ggacagcccc acaatatcgg ccccactgat cgcggcggga atcgcctgct
    12781 cctgaatgga ggaaggagta tcgaagccga gcacttcgat agcctccaga atctccggtg
    12841 aaataccaag agccgaaaaa gaagatgttt gagtcatggg gaaaaatgat ctgtcaaagt
    12901 cacggaagaa gctgaacatt cttccctccc gtgtccagcc aaaagaacgg aagataccgt
    12961 agatgccacg atttccgcaa agccgcctgc gaataaaaaa acggctctcc ccgcttctgg
    13021 tctttactgt cacacacggg gttgcaactt gcaggggcgc attcgcgtat gatacaaata
    13081 tttccctccg aattcatgga taaaacgcca aacaaatcac agtcctccct gctggggatt
    13141 ttcatcaaca tcctcctccc ggtgttgatt ctggactatt gcagcgcggg gcccgccaat
    13201 cccctggaac gcccggaagg agaaaatttc tggcatatcg gcccggtatg ggccctcgtc
    13261 atcgcccttt ccctccccct tgtctatggt atccgttccc tggtcgtctc caggaaattt
    13321 gacctgatgt ccgtcgtagg catggccggc gtgctgctga cgggtgtcat cagcatcttc
    13381 gtcatcggcc cggaagggcg catccacagc gccacaccct ggctgttcgc cggaaaagaa
    13441 gccctgatcc cccttatcct ggcggcggcg gtcgtcgtct cccggtccgc cggcacgccc
    13501 cttctcaaca tgtttatcta cacgccggag ttattcgacg tgcgcaggat agaacaaacg
    13561 gtggccgcca acggcgagga acgggcttat cagaaactgc tggcaaactc gtcctggatt
    13621 ctggcgggca cgctggttgc ctcctccatc ggcaatttct tcctgagcct ctctttcatg
    13681 tcttccgtca tacaacagcc ggaagcggaa cagcaagtgg cctacaacgc cgccatcggc
    13741 agcatcacct ggtggggctt cctgatcatc ggaatcccca tcctggcagc ccttgtcttc
    13801 atcatgaccc gcctgattaa acggctcggc aggctgaccg gcctctcgcg ggacgaactc
    13861 cttctcaaat aacccccaaa ccatgcgcct ccatacttca tgcatcctgg ctgccgccat
    13921 cgcccttcat gcggcgtggg cggacacgcc ccggttcgac cgggtcttcg gttcccatat
    13981 ggtacttccc cacgggaaaa acattcccgt ttccggtacg gccgccccca acagggaaat
    14041 aaccgtcact tttggaaaca ctgccctgaa aacaaaaacc gactccaagg ggaaatggag
    14101 cgtcacgctg ccccccatgc ctccctgcgc cacaggccag acgctggcgg ccgtgcaaaa
    14161 cggggactcc gccaaattgg aagatgtgct cgtgggagaa gtgtggctgg cttccggcca
    14221 atccaacatg ctgttccgcc tgaaccagac cacgacggcc aaagaagaca tagcggcttc
    14281 cggagacgac cagctccgtc tgctcaacaa cgttccgcaa gcccacacca acaatgcccc
    14341 ctactccgcg aaagactttg acgccgtcac cacggacaac ttctataaag ggcaatgggc
    14401 tgccagctct cccgccacct cagggccaat gactgccgtg ggctactact tcgggaaaaa
    14461 actccgcgaa gggctgggca ttccggtagg catcatccac tcctccctgg gaggctcgga
    14521 aatcgcagcg tggatccccc ggcaggttat taatgccaac aacagcttcc gcaccctgcg
    14581 cggtaatcac tggctggact ccccccttat ctccgactgg gtgaggggac gggccaggaa
    14641 aaacatctct ccgcgtctga accagggctc tccggaccat ccctacaagc cggcgttcct
    14701 ttacgaatcc ggcatcgcat ggacaacggc cctccccatc acgggcgtca tctggtatca
    14761 gggcgaatcc gatgcggaga tcattgacaa tgcccaaaac agcatgctgc tgaaaaccat
    14821 gatctcctcc tggagaaaag ctttccgtaa cccggaaatg cctttcgtca tgatccagct
    14881 cccccgcatc aacgacccgt caaaaatccg tgccggatgg ccggaattcc gtgaaatgca
    14941 agacgccgtg gccaaaaccg ttccaaaagt ttacagcgtc aacaccattg atcttggctc
    15001 caccaattcc gacgttcatc ctccattcaa gcgccctgtg ggggaacgtg caggaaatac
    15061 tgccctgaac aaggtttacg gtaaaaagat cccctgtgaa ggccctgccc tcaaggcctt
    15121 caaaccttcc ggttccaaca tcctggttca actggatcaa gctgccggac tgaccaccac
    15181 ggacggcaaa gaaccggccc agtttgaaat tgccgggacg gacggaactt atcatcccgc
    15241 cgcagcggaa atcataaaca gaaaaggcaa cacagccgtt atccgcctct catcaccgga
    15301 agtaaaatcc cccaaacacg cccggtattg ctggaaccgt ttcgtgaccc ccaacctggt
    15361 caacggcaac cagctccccg cccgtccctt ccggacggac gaacctgttc tgaaaaaata
    15421 acttttacca caccatcact ccatgaacct tcatcttatc ctcgcttctc tgacagccac
    15481 actctcactg ggcattgcgg cacaagctgc tcccgccaaa gtagcctgtg tgggggacag
    15541 tatcaccttc ggcaccggcc ttaaacccgg agaaacccgg tatccgcaag tgctcgccac
    15601 actcatgggg ccggactttg acgtcagagg cttcggcaat cccggaaaaa cggcaggcga
    15661 ctacccgggc caggcaggac gctggtacgg cagcaccagg gaacacaagc aagccctgga
    15721 attcaaggcg gatatttata tctgcaacct tggcatcaac gacacgggcc gctggtggaa
    15781 ccccgaactg ttctccaaag gctatgacgc tctgcttcat gcgtggaaaa acgccaatcc
    15841 caaaacacgg ttctttgcct gggggctgct ggggccggac taccgcggcc cgctcaacaa
    15901 aaaggcattt cccggcaact gctatccgga cgtacgtaaa tatgcaggct cggacaacgg
    15961 ctcatccgcc aaccgcccgg aagcggaaaa actgatcgcc gccgtagcgc gcaagtacaa
    16021 agtcagtctc tttgacgcgc tgcacccgct ctccgaccat ccggaatggt acgttgacgg
    16081 gttgcaccct acggaacagg gcgcacggcg cattgcggaa atcacctttg ccaagctggc
    16141 aaaaagcctc aggcttaagc agcccgcccc cagattggaa ccgggcaccg gcaacgtgat
    16201 tatcaacaac ccaggcaact ccggcatcct tttggatgga tggaaactga cggacggaac
    16261 caatacgctc atctttgaaa actccaccgt cattcatccc aaggacaggc ttatcatcgc
    16321 cattggcccg gaaactcaaa aagacccgac caagcccctg caaatcaagt cctcccaatc
    16381 ccccgcagct ttccgcctca ttcctgcgaa aaaatattaa aaacttccag aaccgcttat
    16441 gggaacatgc ggaactcctg catgttccca taagcccggc acacgctatt c
//
