LOCUS       c00052_gnlPro..        13926 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONKPDECO_52.
ACCESSION   c00052_gnlPro..
VERSION     c00052_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:20:18
            Original ID  :: gnl|Prokka|ONKPDECO_52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13926
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13926
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[967:3926]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      968..3926
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13926
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13926
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             968..3196
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_1"
                     /sec_met_domain="Gly_radical (E-value: 2.3e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             3201..3926
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_2"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(4158..5420)
                     /locus_tag="ctg52_3"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVEMGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(5472..6020)
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LLHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             6208..6960
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(7065..8063)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg52_6"
                     /sec_met_domain="LysR_substrate (E-value: 1.2e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 4.8e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             8133..8606
                     /locus_tag="ctg52_7"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8710..9708)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_8"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.5e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9763..11031)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_9"
                     /sec_met_domain="MFS_1 (E-value: 4.1e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(11281..12294)
                     /locus_tag="ctg52_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTTALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFLVVLKNIEKLTNPDGYVLPVALKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTLLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(12317..13426)
                     /locus_tag="ctg52_11"
                     /transl_table=11
                     /translation="LLACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 ataccaatta attggtattt tattacaaat aaccattcaa tttcattatt atgcccaaag
       61 catgaaaata aaagtataac atacaagagc tgtaaacaaa tccacgatca acacaataaa
      121 ataaatcgtt tttgcatctt tgcgatatgc atttatgcaa aatcatacaa atttctttat
      181 cagtaaaata cccattaatt agtatttcat tgacaaaatg aaatgtactt taaaagccca
      241 aagttatatt caattcataa cctaaatgcc tatccaatat aaaaataatg cgtttagcac
      301 caagatacaa acagaataac acaaaatcaa gctctaaagg aatgtattac tattataaaa
      361 gacagaatta ttcgggagat tccctactct aaaaaagtta aagaaagaaa atgattcaaa
      421 taaatattag tataacaata tcaccaacaa cacaatatcc ccttttcaaa ttatacaata
      481 aataatagtt aagcaaccaa agacagtgca aagccaaata agtaataaaa gaacaaagta
      541 ttaaataaag caaaaacacc caattttact ttttagggtg taaaattggg tgtttttctt
      601 gtaaatcact gattttcagc atttattgcg gagagacagg gattcgaacc ccgggtacct
      661 cgcagtacaa cggttttcaa gaccgccgca atcgaccact ctgccacctc tccagaacta
      721 cggttaagta gtgcttttct cttaaagcgc tgcaaaggta cgaatcattt tttaacttgc
      781 aaattattcc gcaaaaaaat attagaaaag tatatttgga agtaataacc gccctctggc
      841 ttctccccat aaataggtat ttttatgcta ttcaacataa aataggaccc ttttatatac
      901 ctaaaccgaa aaaaggttgt aaatttgcgc gctctaaagg ataactaacc actaactgat
      961 taattttatg gaactgaata agacctttaa agatggactt tggagcaaag aaatcaatgt
     1021 aagggatttc gttagtaaca acatcactcc ttatgaaggg gatgcttctt tcctgcaagg
     1081 acctaccgaa cgcaccaaag ctgtctggaa tcactgtctc aaagctctcg aagaagagag
     1141 aaacaataat ggtattcgtg cactcgacta cacaactgta tctactataa cctctcaccc
     1201 tgccggctac atcgataaag aaaacgaact gatcgtcgga ctacagaccg atcaggtgtt
     1261 aaaacgtgcc atcaaaccgt ttggcggaat caatgtggtt atgaaagctt gccgtgaaaa
     1321 cggagtggaa gtagatgaca gagttaagga tatcttcact cactatcgca agactcataa
     1381 tgatggggta ttcgatgtgt ataccgaaga aattcgttcg ttccgttcat tgggattcct
     1441 taccggactt cccgacaact atgcacgcgg acgtatcatc ggtgattatc gccgcctggc
     1501 tctctatggt cttgaccgtc tgatagaagc taaaaaagaa gatctgcata atctgacagg
     1561 tcctatgact gaagcccgca ttcgtcttcg cgaagaagta gccgagcaaa tcaaggccct
     1621 gaaagagatt aaagtattgg gcgaatatta tggtttggat ctgagccgac cggcatatac
     1681 cgcacaggaa gctgtacaat gggtgtatat ggcttatctg gctgccgtaa aagagcagga
     1741 tggtgctgcc atgtcactgg gtaatgtatc ttcattcctc gacatctatc ttgaatatga
     1801 attaagccag ggtacgataa ccgaaacatt cgctcaggaa ctgatcgacc aattcgttat
     1861 caaactccgt atggtacgcc acttgcgtat gcagtcgtac aacgatattt ttgcgggtga
     1921 tcccacatgg gtgaccgaat ctatcggtgg acgtttcaat gacggacgta ccaaagttac
     1981 taaaacttct ttccgcttct tgcagacact ttataactta ggcccgtcac cggaacctaa
     2041 catgactgta ctatggagcc ctgagttacc cgaaggtttc aaagcattct gtgcacaagt
     2101 atctatcgac acttcttccg tacaatacga aaacgacgac ctaatgcgtg aagtccgtca
     2161 atcggatgac tacggaatcg cttgttgtgt ttcatatcag gaaatcggaa agcagattca
     2221 gttcttcggc gcacgtgcca accttgccaa agccctgcta ctggctatca acggaggacg
     2281 ttgcgaaaat acaggtacag ttatggtaaa agacatccct gtattgaccg gtgaaacact
     2341 gaagttcgaa gaagtaatgg ccaactataa gaaagtattg atacaaattg cacgtgtata
     2401 caacgaagca atgaatatca tacattacat gcacgataag tattactacg aaaaggcgca
     2461 gatggctttc gtggatactg atccccgcat taacctcgct tatggtgtag ccggactttc
     2521 aatcgccatc gattcactgt ccgccatcaa atatgcacat gtgaaagccc gtcgcaacga
     2581 catcggactg acggagggat tcgatatcga aggtgctttc ccttgtttcg gtaatgacga
     2641 tgaccgtgta gaccacctgg gtgtagacct ggtatatttc tttagcgaag aattaaagaa
     2701 actccccgta tataagaatg cccgtcctac cctctcgctg ctgactatca cttcgaacgt
     2761 aatgtatggc aagaagaccg gtgccactcc tgacggacgc gccaaaggca ttgcctttgc
     2821 tcccggtgcc aaccccatgc acggacgtga taaaaatggt gcaatcgcct cactgagttc
     2881 tgtagccaag ttgcgttatc gcgactcaca ggatggtatc agcaatacat tctcaatcgt
     2941 tcccaaatca ttgggagcaa cacaagaaga ccgtatcgac aatctggtga ccatgatgga
     3001 cggatatttt acaaaaggcg cacaccacct gaacgtaaac gtgctgaacc gggaaatgtt
     3061 gcaggatgcg atggaacatc ccgaaaagta tccgcaactg actatccgtg tctcaggata
     3121 tgccgttaat ttcgtgaaat tgagccgcga acatcagttg gaagtaatca gccgcagttt
     3181 ccacgaaaga atgtaattga atgataaacg tacactcata cgagtcaatg ggaacattcg
     3241 acgggccggg tctccggctc gtcgttttcc ttcaagggtg taacttccgt tgcctctatt
     3301 gtgccaatcc ggacacaatt gaagccaaag gagggacagc aaccgaccct gaggaaatag
     3361 ttcgcatggc cgtcagtcag aaagctttct tcggtaaaaa gggaggtatc accttttccg
     3421 gcggagagcc tacttttcaa gcaaaatcgc ttatcccact ttttaaaaga ctaaaggaag
     3481 caggaatcca tatttgcctt gataccaatg gcgggctatg gaacaatgat gtagaggaac
     3541 tattggaatt gactgatctg gttttattag atatcaaaga atttaatccg gaacatcatc
     3601 agtctttaac cggaagaagc aacgagcaga ccctgaaaac cgcagcctgg cttgaaacca
     3661 atcataaacc attctggttg cgatacgtat tagtgcccgg ctacagtgac ttcgaagacg
     3721 atatccggca gctgggagag catcttggaa cgtaccagat gattcagcgt gtagaaatat
     3781 tgccttacca caccttgggt gttcacaaat atgaagcaat gaacaaagaa tatatgctga
     3841 aaggagtgaa agagaatact ccagagcaga tagaaaaggc tgagaaacta ttcaggcaat
     3901 atttccagac cgtacaagta aattgactta tataagtgtc gaaattcgta ttcaccacag
     3961 attacacgaa tttacacaaa taaagatcat tggcaatcaa tagattaagt tcattctgcg
     4021 gtgaattatg acgactgcac ttatttataa ttttgtaagt cacgatataa aagtctccct
     4081 gttcttgcct taattcatta caatacaagg caagaacagg gagataatgt aaccggcata
     4141 ttttttgcca tcctacttta ataagtgaat cgcaatcctg cctgcaagtt aaagttacaa
     4201 ggcctttctt ttcggatggt ttgtactttg gagccatcat caaagaaata cgaaactccc
     4261 ggttccacat ataggccgac atgatctgtc gcattgaatt gcgctcccac ggcaccggct
     4321 acagaaaatt gcaaaggctt cacattcacc ttatcatccg ccaactttcc ataaacacac
     4381 ttttcaacca ttcctccggc agatacatag agtgtaaaat atttcttttc cagaaaattc
     4441 cagtttccac gtacaggaat acctatataa tgcaatttct gactctgcat cttggtatcc
     4501 ccctgccgtt tgatgtcaga agacaacaac gtataagtca atcccatctc tacagaaaaa
     4561 cctttgggaa gagacttacg tacagacagt ccgaagctaa ccggctgatg atgttcataa
     4621 tccaccacgg cagttgtatt ggacttcagg taagggactc cttcttcaaa tataacttcc
     4681 tgatcggcag gaatactcac agctccattc atgatcgtca tcaagtcgac cctgttagtc
     4741 atcggacggg gcgcaaaatt ttcggaacca tttgtcggaa gtccacctcc attaccgata
     4801 cccactccca tcgaccattt accaccacgt ttagcagaag agtctccgat aggcaactga
     4861 tacttgtctt taccagacgg tcgccgcgct tctttcctct ttggaggctg cgccgtcgca
     4921 ctttcttttt tctcgattgc agcaattgct tcctgttgcg gctcagatct cttttcctcc
     4981 gtcactgcct ccggtcgctt ctctaccagg gaggatacct ccggaacaat caccggatca
     5041 gtattctttg ccaaatagcc cgaaacaggg ttaatactcg tcgttcctac cggcttaact
     5101 ggttcggata cagctacctg tacatccggc aaggcaggtt ccggcaatac atccgggttg
     5161 acagccagtg aaggagccgt tgcataacgg atttcatcag ctaccggact attcagaaaa
     5221 tacaaactga cagcagtcgt tagcaccaat accacagctg ccgcagcaac cgcccaccgg
     5281 cgatacggat atattcgttt ttcggttaca ggcatcagtt ccctttccag tcgttcccaa
     5341 ccggaagcag gcatcggctc cgaataatct tcgagcttat ccttgaatgc tttaatccat
     5401 ttttcgtctt ctttcatcat tctatttcat ttttgaaatc caaggttcac ctcagtatct
     5461 gtaaatacat gtcaaccatt ggtcaccaac cattctttca ctttctttgc caatacactt
     5521 tttgcacgaa aaagctgtga agcagaagat ttttcattaa tccccaacat ctgtgcgatt
     5581 tccttgtgcg acttatcttc aaaggtgtat aaattgaata cggtacgata tccggcgggg
     5641 agttcattaa taaattgcat cagcactttc tgtggtattg cttcaacagc cgaagcatcc
     5701 ggttcttcat acgtttcggg aacttcatcc agtgccgtgg tctggttcat cacgtcgttc
     5761 tttcttaaga actgtaaagc cgtattcacc attacacgct ccatccatgc tctcagagag
     5821 ccttcacccc gccaggtaaa cttgtcgaag gagtcgaaaa tcttcaggaa accgtcgtgt
     5881 agcaagtctt gtgccatgtc cctgtctccg gcataacgaa gacagacacc aagcatgcgc
     5941 cctgcgtact gctcataaag ttctttgcgg gcacgattat ctccctgcct gcaacgttcc
     6001 gacagctcta attcattcat tctcctaaac acgtgtttac cttataaatg cagcaaagat
     6061 agaaatactg cacagagaga acaactcttt tatcactttt gtttctttaa cattttagga
     6121 tgcaatattt catcacttcc tgcattttct caatacaata aagaataaat ctcaatggat
     6181 aaataggata aaaccaacaa gaaacttatg aagaaattta atttaataac ttttgccgtc
     6241 atcctgatgt tattgcccat tttacagtca tgtctggacg atgccaacaa cgacgagtgg
     6301 gtcacttgtc ctccgggtgg aatattagcc atcggcacaa tgaagattcc caatgcggac
     6361 actccaaggg actttttcat tgcgttggac aatggagaca atgtacttcc ggcagatacg
     6421 gccgatatac gcaacaggaa atacactgtt gcagaaggtc aaagagtctt cgttggctat
     6481 ctgcagatgg gagaagagaa acccggatat gagaacggta aaatattcac gatagaagat
     6541 atattgacga aagagatcat tccactgacg gaagctacag cagacagcat tggagacgac
     6601 cgtatcaacg tcacagcgca tgcacttacg aaagattatc tgaccatcga atatcaatat
     6661 ctgggcagca tgaatgaaaa taaaaaacac atgctgaact tggtacaaaa cgaaataaca
     6721 ggtcccataa aagatgacgg atatatctat ctggagttcc ggcataatgc ctttaatgac
     6781 tcccccaatc aattgggttc gagccttgtt tctttcaagc tggatagtat agccgagcaa
     6841 ttggcgacag ccaaaggaat aaaactccgt gtgaacacca tttatgacaa tatacagtat
     6901 gtcacaatag atatcaacga agacaaaaac ttaaaaataa aatcatttca ttctcaataa
     6961 aacaacaaga aacacctaca caatcaggca aaacgagtaa taattctgat acataaaaga
     7021 aataaggcgg cgatgtttgt gaaaatatcg ccgtcgtttt tatattatac cagacactga
     7081 acggcctgca gggtaagcat ctccttggga accgccgcct gaatctcctc tttcaaaacc
     7141 tgcagcagac tggtgcggat gaagtctttc cgggtcacca ggacaatctg acgggtaggc
     7201 cgcgggatag caaacggacg gaccagttct ttctgctctt cgctcaattg catcactgcc
     7261 agttcgggaa taaacgtaat ccccttacca ctctccacca tatgcataaa ggtttccata
     7321 ctacccagcc gatacgccat ttggctgatc ttaaccgctt ccatctgaca aaaacgaacc
     7381 aactgatcgc ggaagcaatg cccttcgtca agaagccaaa gccgttcccc tgtcacatcg
     7441 gacgtacgaa tcacatcgtg cttgaacaac ggttccttct ttgagacata gcccaggaat
     7501 tgctcgtaaa ataaggtctc ttccgttaat gcggcatcat ccagcatgct ggcaatgata
     7561 gcagcatccg cttcaccggt cagcagagcc ttgcgaatgt cgggcgtctt catctccatc
     7621 acccgtatat caagatccgg gtatttctcc atcagttgcg gaaagaaacg gggcagaaga
     7681 taaggtgcaa tcgtcggtaa cactgccaat cggaatgtac ccgacaggga gtgctgttct
     7741 tcgctgatga tctccttgac acagataact tccgaaagaa tcttacgggc ctgttccagc
     7801 actttcttac caatggcagt agggcaaacc ggtgtcatgc tacggtcgaa cagtttcacc
     7861 cccaattcgt cttccagctt ctggatcatt gcactcaaag taggttgcgt cacccggcaa
     7921 tactcggcag ctttagcaaa atgccggaac tggtccacag ccagaatata ttccaattgt
     7981 tgtatagtca tcgttctctg atttattaaa gatatagaat ctatcaatgc aaagatagaa
     8041 attttcagtt tgacacgaat cattttgtgc cgtatctttg ttccagataa aaagaagaaa
     8101 tatagtatta actcaaaaaa aacaatatca ttatgaagac tttaaattat acacatttgg
     8161 aagaaaaagg agctaacacc atcgtactgt cattacagca actgcttgcc gattttcaga
     8221 ttcattatgc aaacctgaga ggatttcact ggaacatcaa aggacacggt ttcttcgtac
     8281 tgcacagcaa gtttgaagat ttatataatg gagccgccga aaaggtggac gaaatagccg
     8341 aacgtatact gatgctggga ggaactcccg ccaataaata cagtgactat ctgaagatgg
     8401 cgcagatcaa ggaagtggac ggagtgaata aggccgacga cgctctgaat catattctcg
     8461 aaacttacgg gcatctgatt gcggaagaac gtaaaatcct gtctctcgcc tcttcacaca
     8521 acgacgaagt aacagtggcc atgatgagcg actacctgaa agaacaggaa aagatggttt
     8581 ggatgctgac tgcatacaac ggataacagc cgaaagggtg tagccatctg accgaaaagg
     8641 tgtagccata caaacaaaag ggtgtagcca tcccggcggg atagctacac ccttcctgtt
     8701 ttattcgatt cagatgatac ttgtacgttt ggtaaattca ataatctccg gaatgtatcc
     8761 gaatgcgagc ccggtcactg tatccgcaca cccataatag atggcaatcc gtccggtctc
     8821 cgaatcatga agcgccgcgc atgggaaaca gacattaggc acatcaccca tacattcgta
     8881 atccttctga ggtgaaatca gataaggccc cgaacggaat tttactttcc agggctgatc
     8941 gatgtcaagc agtgccgaac caaaactata cacaaaaccg ttgcaggaag ccaatacacc
     9001 atgatagatc agtaaccagc cttccgaggt ttcaatcggg ataggccctg caccgatctt
     9061 ggtacactgc caggcactgt cttcgaacgg agccggcgac ataacatgac gatgacgtcc
     9121 ccaaaactcc atatcgggag actcgctata gaaaatatct ccaaaaggag tatgcccatt
     9181 atcactcggg cgactcaaca tcgcaaaacg accgtttatc ttacgaggga acaagactcc
     9241 attccgattg aaaggaataa aggcattctc caactggtga aaagtaacaa aatcataggt
     9301 gtaggccaca ccgatagtag gaccatgata gccattacac caggtcacat agtagcggtc
     9361 ttcgataaag caaacccgtg ggtcatatcc atagacccag gttccaacct cagcatcatc
     9421 acattgaaac tttaacggtt cttcgttgat atcccaatga acagcatcct tgctgaatcc
     9481 cacatgcaaa cgcatgcgac gattagtatc atcacaacgg aacacccctg catagccatc
     9541 cttaaacgga actacggcac tgttgaatat actgtttgaa gtagggagca agtcgcgcgg
     9601 aataatcgga ttggccgaac aacgccacac tacatcttta catcctgccg gacgttcttc
     9661 ccaaggcata gctggcaaag cagcacctgc aattttaatt tcttccatga ttcgattaaa
     9721 ttaatattat gtatatatct tgtttatatt gaaaatctct ttttatttct tctttccgtc
     9781 cggatatgtg aaaggtacca gccaagtcac gataaaagcc ggtatggtag cgataagtac
     9841 ccagataaag aaatcgcgat aacccagcca atcgctcagg tatccgctca tcattccggg
     9901 aagcatcacc cccagattca taataccggt agcaaaagca taatgtgcca tctgatgttt
     9961 gccgggagcc acttgctgca tcataaagag catcaatccg acaaaaccaa acccgtaacc
    10021 caagtattca gacacaatgg ccataccaat aatccataga tcggaaggct ggtaaagggc
    10081 taacaggaaa tataccaaga acggaatatt aaaagcgcaa cataaagaaa acaaagtctt
    10141 ccgaagtccg aaagccgaaa tgtaataacc ggccaaaagc gaaccgagaa taaaagctcc
    10201 cgctccgaac gtaccatata ccagtccgat atcctgagtg ctgagtccca atccaccatc
    10261 cgcaaccgac gctttcagga acaacggtac aatcttgatg gcatatcctt cggcaaaccg
    10321 gtacaaaatg ataaagacaa tgtagaaagc aatatgtttt ttttggaaaa aagagcggat
    10381 gacttcccaa agcatattca atgcgtcact catcgtattc acttcaccgg aagcgcctcc
    10441 tcccgaaggc aaaatccgga tgtggtaaag accgatcaga atcataatac ccgcacacat
    10501 caacatgaca atcatccagg catgtaccac tccaaattca tccttcagca tacctgccag
    10561 ccaaaccaag cctccgttgg caagtatctt ggccagatta taaaaagctc cctgccaacc
    10621 gatatacttg gcttgctggg tagcagtcag ttcagtcagg tatactccgt cacccgcaat
    10681 gtcatgagtc gcaccactga gagcaatgat ccccatcaga gcgatggcat aacgaaaaaa
    10741 gtcgggcagc ggcagcgaaa gtgctaccaa tgcaaatgcc agtccggtaa tgatttccgt
    10801 agcgacaaca aagtatttct tcgttttaaa catttccaga aacggactcc ataaaggctt
    10861 caatgtccag ggaagcataa tgagagaagt ccagaaagca atctgtgcat tcgacacttc
    10921 catatcggaa aacataagga cagaaaccat cgaaagggcc acaaacggca atcccatagc
    10981 aaagtaaaca gtaggcaccc aacatacagg gcttatcggc tttttattca tcagttagtt
    11041 ttttataata attccatcgg ttaacaattc cagtaagcaa agatagggga tattaaaaac
    11101 ataacccaag attacgacaa gaagttgctt tcattattta ataatacaac tcacccggga
    11161 aaactactaa cctctatcac ccttttttta ttaaacttta tcaatacaat acacgcaaag
    11221 aagcaccgaa gactttcatc cccgatgcct ctcgccccct tatctacaat ctaaacacct
    11281 ctattgcttc acatataaat ttatctcagc aaacccggta taattatccg gagtcagaca
    11341 gtttattctg aattccttta cattcgggat aggtggttcg atggccgcat attgcggatc
    11401 agccccttta aaatttctga aagtcaagac tctcgggtaa gtaacccact cggtttcacc
    11461 ctctttccga accttaatct cagcacttct caggttataa cccgatccgt aggcactctg
    11521 tttagtgacc gaaaatccgg ttaaggtaac aggccggtcc agtagcgtat tccaccaaca
    11581 ctctccggca ttagccactc cccatgtaaa ccaagtagta tttatctcac cgtcaatagc
    11641 cagatgtgca ccatatttgg catcatcatc ggcataaaca ttgctgcaac ttacactcca
    11701 cgcacttcga tctacagcgg accaattccc gggtttcgta taactggtat aaagcacgct
    11761 ggtataaatc cggatataaa ccgtcttcat agatgtactg acagcctgtt cgtccatgcc
    11821 cgtaactcct ttaagcgcca cgggaagcac atatccgtca ggattagtca acttttctat
    11881 attcttcaaa acgaccagaa aagatgaatc ggccactgtc tgtcccgttt ttaagacaac
    11941 ttcacttgtt tcaatggtat aattatcttg gggcaacaac ttacatttcg tcttattggc
    12001 agaattgtaa gtatccactt tcagcgtatc tactcccaaa gcggtagtga catcccgcgt
    12061 aaccggctgt acggcacaca attgtatttc aaaatcagaa cggtcggcag tagaggaatt
    12121 gctcacacaa tccaccacta ccgcagcacc catttcggcc cccggtgcaa ctcccgttct
    12181 gatatatatc ttttgatatt tgtccatttc atcatcatcg ttgctgcacg aagccaacga
    12241 tacaaagcct gttatcaggc agattaaggt cacaaaattc aaatgtctat tcatatctta
    12301 tcttcttttt acatagttat tgcttatcaa aacgaacatg ctctttccag acaagagttc
    12361 ctcctgccac caaatcgtat ccgtgtccgg tacagtcggc aaaggcattt cctttacctt
    12421 catccatttt ccaatagcct atcaggttcg gatcggcggg tttcacggca aaatacatgt
    12481 tggactgaat ttgcgtctgg ctgattgcgc tcttccaaag acgcacctgg gccatctgac
    12541 aattgttgcg gaagtagcta ccgctcgaaa ccatgttcat cttgtcgaat cttaccgggc
    12601 caccctttgt ctgcagagtc acgtcgagca ctccgttgat ataaatcgac aataacccgg
    12661 aagaattata aacgaaggcc agatgatacc acttattctt ctcaaacaaa gtcaccgtat
    12721 tgacctgact tccaagtgtc ttcacctgta atgaattata agggatcata gcgtcaccga
    12781 aacggatata aacctcgtgg tcgctgctgc ccgaattaaa tatagcctga ttattaatat
    12841 cgaatccgtc catctgtacc caagcctcga gtgaccattc attggttgtc actccccaca
    12901 attcgtcctt ggcgggcttc acggcattgg tcgtattcat aaacggtaca gactgtatca
    12961 gcggcttatc cagcaaaatg ataaacttcg acgaaagccc gattgtggac accggtccct
    13021 gaatttctgt gagagatacc ggaatagcat acaattctcc gttttcgttt gaataaggtt
    13081 tcactctaaa ctcactgggg attgcgctaa catcgcctgc cgctatcttt atctctttgt
    13141 cataagtaaa atactgctcg ggaaggactt cgtacgaagt ttcattagct tcattgtact
    13201 ctttaagaat agaaggatct accgtcagga cagcagtcac attttcggtt acaggctgtc
    13261 ccacacgtac ggtcagagta gttgttgtta cattttcagg atcaacggta acctttgccg
    13321 aaccattctc ggatgcttca ttcaaataaa tcgcattgtc gataacctgg taatcggcat
    13381 cgttgcatcc tgccaggatc atcggcagaa cgaaacaggc aagcaaacat tgttttattg
    13441 ttattctttt cataatcaaa ttctttaaag tcattttaca gcaggattca ttattctgat
    13501 tgcttcacgc aggtacttat attcgatgtc gcccggatag tcatattcca tgtgataggt
    13561 gcctactcca cccttccgta cctgttttcc gtcaatagtc ggagtccagc gtgccatgcc
    13621 ggcaagtgct ctcattttgt ttccgtaacg atctacataa tcacctcctc ctgtcggagc
    13681 ataagattcg aaattctccg taacgatgta catattagcc actttctccg gaggaagtat
    13741 tcctttaaag ttggcaatcg taccagccag acgtctgtca agattagcgt cggaattacc
    13801 cgcaaggtta gagtatgcct gcacaatgaa atagtcaaag taaggcccgg tttccggatg
    13861 aatactttga ggctcgccat caatcacaag taaccgtccc gtacccgatt taggtccgat
    13921 tctttc
//
