LOCUS       gnlProkkaHEBFBKGL_684  15095 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEBFBKGL_684.
ACCESSION   gnlProkkaHEBFBKGL_684
VERSION     gnlProkkaHEBFBKGL_684
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:49:26
            Original ID  :: gnl|Prokka|HEBFBKGL_684
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6258
            Orig. end    :: 21353
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15095
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10786]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10786
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15095
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15095
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(67..1341)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 146.3; E-value:
                     1.9e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg684_7"
                     /transl_table=11
                     /translation="MNDIAIRFDHVGKLYKLGLVGTGTLSHDLNRWWKTTILRQEDPYL
                     KIGETNDRSKKGASEYVWALKDITFDVHQGDVVGIIGKNGAGKSTLLKLLSRVTSPTTG
                     AIRARGRIASLLEVGTGFHPELTGRENIYMNGSIMGMTRHEISHKLDEIVDFAGVERYV
                     DTPVKRYSSGMTVRLGFAVAAFLEPEILVVDEVLAVGDAEFQKKAIGKMQDVSKGEGRT
                     VLFVSHNMGSMQRLCSRGVLLENGKVKYMGSISDTIRTYQSDEIIQNSFEGTDGNKQIL
                     YLKKASVSSSDGNIFYNSSTIKIEFEICVKKHIPSLVIGFNLYSIFQYPLARADYNDEN
                     KKTSLEPGSYHFTFEIPPYTLSNGEYKIVFDVAERNVKCYTTKKSQLTFNVLQGEDCFG
                     NVFAEDIPIKSSLIRENWLKEIKTY"
     CDS             complement(1370..2215)
                     /locus_tag="ctg684_8"
                     /transl_table=11
                     /translation="MTKENWTIEIKPKKKWLDIDLKGIWRYRDLYYMYVKRDIVTVYKQ
                     TILGPLWFLIQPIFTTVMYMFIFGGLAGISTDGVPQPLFYMAGIMLWNYFSSAFNVSSN
                     VFTANAGVFGKVYFPRLVVPLSGITSNLIKFGIQLLLFIAMYLYFYVKGASLHVNAALL
                     LFPFLTFLIAFHAMSWGLIVSALTTKYRDLTQLVTFGLQLFMYATPVIYPLNAAPEKYR
                     DIIALNPLTPIFETFKYSCMGCGSLDWGGLAYSTLFMLSTLFCSVVIFSRVERNFMDTV
                     "
     CDS             complement(2234..3238)
                     /locus_tag="ctg684_9"
                     /transl_table=11
                     /translation="MRVFNCLSGGILCGLTLLLIFLPCFTPEWAGNLIFISLSAIPICI
                     ADGIIFAILLWKHNRWWMLYLLLLLGSSPILSGYFPLHFLHREEVPDSNQLKLVCWNAE
                     GFRLNKDTLAKAIHSIRILQPGIVCLQERPHTNLLAWDTIRAAFPDYPYCIVNSREDEI
                     LNLAVFSRWPVGNVQEYYFPDSYNKMLQADIRMIGQTFRLFNVHLQTTGMNESSSMKDR
                     LQTMRHHAIRRNRQADLLANAIAESPYPVIVCGDFNDTPASYVYRKISRSLQDCFLQAG
                     RTWKGSYQRWGDFLRIDYTLCSPAFQVNCYQLVSNPWSDHKQQHCVLYLDKRY"
     CDS             complement(3225..3803)
                     /locus_tag="ctg684_10"
                     /transl_table=11
                     /translation="MESIGLRKVWLTPHIMEDYPTPNKKLRQQLDVLKAAYSGPLDLRL
                     SSEYMMDAAFTNKLDGEVLPLGSSHLLVETSYMYPPPGLPDILMKVWNAGYQPVIAHPE
                     RYLYMEEKDYLLLKEKGYSFQLNLMSLSGYYGPHPKVVSEKLLKQKMYDFVGTDLHHLE
                     RYRPMLDQLRLTRRQLEALEGLIANNARI"
     CDS             complement(3968..6178)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 283.7; E-value: 4.6e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg684_11"
                     /transl_table=11
                     /translation="MIKDAYSNNIGRGLDRFNTYSYTNVSNEILQFQSHKLMRDVVNRL
                     HANVCYLIMDDLREEELYTQAPVKVSFPEEEDHLDFSLTVRTLNRKQVRLSDFSTDATG
                     ITLTANLGDTIQSPVGKIVVSPTLYYTDKWFNTPITIRRQSTDTMASLFRSNLNISQAE
                     NDASILYLSLRDYSTARAEDVLNMLITVYNEETIKDKNQIAINTSSFINERLVIIEKEL
                     GGVENELQSYKQNNDIIDIGSAASMSMSDKRQYSSTTQELELQARMARYIKSYLVDPSK
                     ETELIPSNTGIADINIETQITAYNANKLKRDKLIEGSSDKNPIVQELNKNLIAMRQNII
                     RAIDNMIVSIDVKLNEARSRAGEAQWRVTNIPRQQQQMLSIERQQRIKEELYLYLLNKR
                     EENALSQATTETDARVLDPAGGGDAPISPNGRSMIMAGVMKGIALPAIVLLLFLFFDTR
                     IRNRKDIEDAVTVPFLGEIPKDSSKGKTENKETAHGIAVRAQGRDIVSEAFRIIRTNMD
                     FMRVKSKNMQVVTFSSFGPGAGKTYVSSNLAASFAQTDKKVILIDMDIRKGTLTSHTRL
                     HTKEKGMTSFLAGKATTDEIIKHNEICENLDFIPAGPIAPNPSELLLSEQLEVLITELR
                     NRYDYIFVDNVPVGVVADAAITNRIADLTIFVVRVGKLDRRMLPEVEKIYRSGQLNNMS
                     LVLNGAIVKTGGYGGYGYGYGYGYGYVDGSESCWKRLFRKKS"
     CDS             complement(6393..7202)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 74.2;
                     E-value: 1.3e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg684_12"
                     /sec_met_domain="Poly_export (E-value: 5.1e-16, bitscore:
                     49.2, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIKLACLLAMVIFSSCASRKDFVYLQDMDELQEYPMVQKYEA
                     IIHRDDRLSIIVNSKNPELSLPFNMSGSRSYSVEADGTISNNEVGALSDEKEKGYLVDI
                     NGNIDFPVLGQLHVEGLTRRQLTEQIKKRLINEELLKDPMVTVNFLNFKFSVLGEVGHV
                     GTFEVKGDRITLLEALAMAGDLTPRSRLDRIAVIREYGNKRRILFHDIRSKDIFTSPYY
                     YLQQNDIVYVEPTNMKATEQAQRKLSTWSMILSFITTITSLVLLTTK"
     CDS             complement(7224..8912)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 222.9; E-value:
                     1.3e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg684_13"
                     /transl_table=11
                     /translation="MKKLLKKFLQKLTRKNLSNTYQLGRKAFKWVMQVTEGYHWLISFS
                     VFSGIFGVVMSLVNVAMSKWIIDVATGAQKGNIYLVATIVVLSFLSGMGIKLVSPWIFG
                     KINMRISIRMQNSLSDALMMCSWKGAGKWHTGDLLTRIGSDASEVLGMGMGILPNLLVT
                     GLQLTGSFLYLWILDARLAWFILGATPLVLLSKIYFRKVRELSRAQKEMNSEMGTVMQE
                     NLSKRILVRSLGATGYRKQKLHETQEKLFKLGMEQIKFSTFTQGVMGITFGGGYLCAFL
                     WGIFQLHNHEITFGTMTAFLQLVGQVQGPFLGLISIPPSLVRGWTSVERLMALFEDVEP
                     DEHPVYIDQPLTLDFREVSFGYEEGQPVLDRFTATFHPGNSTAIAGPTGTGKTTIIRLI
                     LALVYPEKGRIDLTTDDGRTLSVTPDLRINFVYVPQGNTLLSGTIRENLWLGSPGVDEE
                     TLHKVIRLACAEFVFSLPEGLDTRIGEHGYGLSEGQAQRIAIARALLRPGRIWLFDEAS
                     SALDTGTTTRLMDNLLQWGKNNTLIFVTHDPRLMERCDQVIHIKE"
     CDS             complement(8909..9772)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg684_14"
                     /sec_met_domain="NTP_transf_5 (E-value: 4.9e-26, bitscore:
                     82.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEVDTLERVNRQHGETLKGLQQIYAQPPSIPLLLLKGIGLAGFY
                     PHPEHRIAGDIDLWFGNEAQTEEANQRMEKLGLPVKRGANGEASCLINRVLVEHHSRLI
                     ELHNPFLQKKIRQWEAEVFANSQGKLPSEANHLLLSTHILKHLINEGIGLRQLCDVAMA
                     FNALHSVTNKNELERICHKWHIHRWNQLLYALLIKYLGVPADLLPFSTSLCPDKLMQEI
                     WESGNFGHGDERYGERPSGKWANKRYTLKRVFHKMHLSSGYAFDETFWWLSGLALLRFK
                     EMIKGK"
     CDS             complement(10001..10270)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg684_15"
                     /sec_met_domain="PF05402 (E-value: 1.8e-16, bitscore: 50.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.3e-10,
                     bitscore: 29.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNPNLILRQVGGEYMIVNPFSEAMDMAQVYSMNETAAWLWKQL
                     ENKEFTADEAGALLCNEYEVNKDTARNDANELCRQWLETGLAIE"
     CDS             complement(10289..10459)
                     /locus_tag="ctg684_16"
                     /transl_table=11
                     /translation="MLEERSVFFARSAGSVKNVRSSKFKTLYYQRIINELTFYSPLHLP
                     VKVYVILTIIG"
     CDS             complement(10401..10508)
                     /locus_tag="ctg684_17"
                     /transl_table=11
                     /translation="MNSNLFNSDMTNKTIRNVRRKIRFLREKRRICKKC"
     CDS             complement(10505..10786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg684_18"
                     /sec_met_domain="PF05402 (E-value: 6.8e-18, bitscore: 55.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-15,
                     bitscore: 47.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKEFIKRNIAGEIVLVPSGQTAREFNGMVTLTGTGEFIWEHI
                     EETESFSHLVQLILEEYEVDKDTASQDAAGFIMQLLQAGMVRPTGINW"
     CDS             complement(10783..11190)
                     /locus_tag="ctg684_19"
                     /transl_table=11
                     /translation="MLRTLIEEGKQVSMIISGSSMAPFLIHARDHICLERPSGELRKGD
                     MVFYQRSNGEYVMHRIYNVKKEEYYLIGDAQTVIEGPIQREQIFAVVTKVKRKGEWIVP
                     ENFRWKFFAHVWLNIIPLRETIIKTYRFFKR"
     CDS             complement(11241..12116)
                     /locus_tag="ctg684_20"
                     /transl_table=11
                     /translation="MRLNIGPLTIELSGVTEQEIPVNSRLFLDRKPADKRADRHYTFHF
                     VGRLPLPSNDWQAIFRRNDIVIFRKEERETRLLAIGNLNACYALYQEKDERNADIYFIE
                     GLKRELQTDTLFISCLCLERPLSARGCYILHCAFLDYRGQAILFSGPSGIGKSTHAALW
                     CRHIPDTRVLNGDRALLCPVPNGGYEITGWPVCGSSGICHNERHPLKTIVFIEQAPDNA
                     IRPQTVLKHFKALCSQVTINWWNPKLTRKALDDLLVLTGQTSISTYACNMNPEAAFTLH
                     RYLTELGIIR"
     CDS             complement(12129..12884)
                     /locus_tag="ctg684_21"
                     /transl_table=11
                     /translation="MVRILQTHKPRRINVTLYGSSRETYGRLCHNPQGYTLCVEALKRL
                     KKAGIDVKLNVSIVRKNEKDYDEIIRLTRQLDIPAEVNSYMFPLSRPECGSLRNIPAER
                     LDADKAARIEMQYVEYKKGNDMARYMHNLKYTLALVEGTQACSLECRAAKSSCWINWQG
                     ILTPCVMMDQPAVNLKKVPMTTAWRLLLEEAKELVSHTECEGCHLRPVCNVCYAAAHCE
                     KTITGNMDYLCQMAKAKEQIIMDYPSVTH"
     CDS             complement(13574..13723)
                     /locus_tag="ctg684_22"
                     /transl_table=11
                     /translation="MNKLTPIDIHATTVVHYPMVKKVNMFLKTQVKNAYSLIRPKEILS
                     LFIN"
     CDS             13993..14496
                     /locus_tag="ctg684_23"
                     /transl_table=11
                     /translation="MRYCDLNLLEDYVTKILRNIVMQCFINMLCYMNIVVIENRDCIMF
                     KRSYNKSIYMRFCCRFIFFIASSIEIFIFVNSRIILLIFICIQIYHATYVTITYIRSRI
                     FARCHIFIRYKLLADKRWFCIHFLFHSISFFFDSCSGGREIRKDLRQSRELSSRGTMVK
                     ENLK"
     CDS             complement(14667..15095)
                     /locus_tag="ctg684_24"
                     /transl_table=11
                     /translation="MIVSQELNQKKMEKKKYIKPILESEVFIPQEYVASCYDYDALFYC
                     EKGKKGQDGHGAPCATTTVEVRGAQAQGWETGNKTGNSISNIDLNGFNLNEELSIGTVI
                     PSVKWISVDPNGTGTYYHSGSGKITSKITQIIGRPNHS"
ORIGIN
        1 aattgttttt tgatatattt ttcatcatta ataggtgcaa agtgcgacag ataatttcat
       61 gctgatttaa tatgttttaa tttctttcaa ccaattttct ctgataagag aagacttaat
      121 gggaatatct tctgcaaata cattaccgaa gcaatcttcc ccttgaagta cattgaatgt
      181 caattgcgac ttttttgttg tgtagcactt tacatttctt tctgccacat caaaaacaat
      241 tttatattct ccattggata gggtgtaagg aggaatctcg aaagtaaagt ggtaacttcc
      301 cggttctagc gatgtctttt tgttctcatc attgtagtcg gctcgtgcca gtgggtattg
      361 gaagatgcta tatagattaa atccaataac caaagaagga atatgtttct ttacgcatat
      421 ttcaaattct attttaatag tagaagaatt gtagaatatg tttccatcgc tggatgaaac
      481 agaggctttt ttcaaataga gtatttgttt gtttccgtca gttccttcaa atgagttttg
      541 aatgatttca tcactttgat aagtacggat ggtatcggat atgcttccca tatatttaac
      601 cttcccattt tccaataata ctccacgtga acatagccgt tgcatactac ccatattatg
      661 actcacaaac aacaccgtcc tcccttcgcc tttcgacacg tcctgcatct tgccgatagc
      721 tttcttctgg aattcggcat cacctacggc aagtacctca tctactacca gtatttccgg
      781 ttccagaaaa gcggctacgg caaagcccag acggacggtc atgccgctgg aatagcgttt
      841 tacgggggta tctacatagc gttccacacc ggcaaagtcg actatctcgt ccaacttgtg
      901 ggagatttcg tggcgagtca tgcccatgat ggagccgttc atgtagatgt tctcacggcc
      961 ggtcagttcc ggatggaaac cggtaccgac ttccaagaga gaggcaatgc ggccacgggc
     1021 acggatggct ccggtggtag gggaggtgac acgcgacaga agtttcaaca aggtggactt
     1081 cccggcaccg ttttttccga taatgcctac tacatcgcct tgatgcacat cgaaggtgat
     1141 gtctttcaac gcccagacat attccgacgc gcctttcttg ctgcggtcgt tggtttcgcc
     1201 tatcttcaga taggggtctt cctggcggag aatggtcgtt ttccaccagc ggttgaggtc
     1261 gtggctcagt gtgccggtgc cgaccagacc gagtttgtag agtttgccca catggtcaaa
     1321 ccggattgct atatcgttca ttcttattct ctttttttaa ttctgctgct tacactgtat
     1381 ccataaaatt gcgttccacc cggctgaaga tgactactga gcagaacagg gtggagagca
     1441 taaacaaagt gctatatgcc aatccgcccc aatcaagtga accacacccc atgcagctgt
     1501 atttaaaggt ctcgaatatg ggggtcaacg ggttgagcgc gatgatgtca cggtattttt
     1561 ccggagctgc gtttagcgga taaatgaccg gagtggcata catgaacagt tgcaggccga
     1621 aggtgaccaa ctgggtgagg tcacggtatt tggtggtcag cgccgatacg atcaaccccc
     1681 acgacatggc atggaatgca atcagaaatg tcaggaacgg aaacaacagc agggcggcat
     1741 tgacatgcag tgaagctcct ttcacataaa aatagagata catggcaatg aacaacaaca
     1801 attgtattcc gaacttgatt aggttggagg tgatgccgga caacggcacg accagacggg
     1861 ggaagtagac tttgccgaac acgcccgcat tagccgtgaa cacattggag gatacgttga
     1921 acgcggaact gaaataattc cacaacatga tacctgccat gtagaataaa ggctgtggta
     1981 ctccgtccgt cgagatacct gccaggccac cgaatatgaa catatacatc acggtagtga
     2041 agatcggttg gatgaggaac cagagaggac ccagaatagt ttgtttgtac acggtgacaa
     2101 tgtcgcgttt cacgtacata tagtataggt cacggtaccg ccatatacct ttcagatcta
     2161 tatccagcca ttttttcttt ggctttattt ctattgtcca gttttcttta gtcatttttt
     2221 gaaatcttgt tttttagtag cgtttgtcca gatagagcac acagtgctgc tgtttgtggt
     2281 cgctccaggg attggaaacc agttggtaac aattcacttg gaatgcaggt gaacagagcg
     2341 tataatctat tcgtaaaaaa tcgccccagc gttggtagct gcctttccat gtccggccgg
     2401 cctggaggaa gcaatcctgc agtgaccggc tgattttccg gtaaacatac gaagccggtg
     2461 tatcgttgaa atcaccgcac acgatgaccg gataaggact ctcggcaatg gcgtttgcca
     2521 agagatcggc ttgccggtta cgccggatgg cgtggtggcg catcgtctgg agtctgtctt
     2581 tcattgagga tgattcattc atgccggtag tttgcagatg gacgttgaat aaccggaaag
     2641 tttgccctat catccggata tccgcttgaa gcatcttatt gtagctgtcc gggaagtagt
     2701 actcttgaac gtttccgaca ggccagcggc tgaagacggc cagattaaga atttcatcct
     2761 cccgcgagtt gacgatgcaa taggggtaat cgggaaaagc agctcggatg gtgtcccatg
     2821 ccagaagatt ggtatgggga cgttcctgca ggcagacgat gccgggctgc aggatacgaa
     2881 tgctatggat ggccttcgcc agggtgtctt tgttcagtct gaacccttcg gcattccagc
     2941 aaaccagttt tagctgattg gaatctggca cttcttctct atgtaggaaa tgaagcggaa
     3001 agtaaccgga tagaataggt gaactaccta atagcaaaag caagtaaagc atccaccaac
     3061 gattatgttt ccaaagcaga atcgcgaaaa taatcccatc ggctatacat ataggaatcg
     3121 ccgatagact gatgaagata agatttccgg cccactcggg agtgaagcag gggagaaata
     3181 tcaacagcag tgtcagaccg cacaggatac ctcccgacag acagttaaat acgcgcattg
     3241 ttagcaatca gaccttctaa agcttcgagt tgtcttcggg tcaacctcaa ttggtcaagc
     3301 atgggccggt aacgctccaa atggtgcagg tccgtaccca caaaatcgta cattttttgt
     3361 tttaacagct tttcgctgac cactttgggg tgcgggccat agtaaccgct cagtgacatc
     3421 agattgagtt gaaagctgta acctttctct ttcagcagaa ggtaatcttt ttcttccatg
     3481 tacaggtaac gctccgggtg ggcgatgacc ggttgataac cggcattcca tactttcatc
     3541 aggatatccg gcaaaccggg aggagggtac atgtaggatg tctcgaccag caggtggctg
     3601 ctgcccaaag gcagcacttc tccatccagc ttgtttgtaa aagcggcatc catcatatat
     3661 tcggaagaca gccgtagatc caacgggccg gaataggccg ccttcaacac gtcgagctgt
     3721 tgtcgcagct tcttgttcgg tgtgggataa tcttccatga tatggggggt gagccacact
     3781 ttccgcaacc ctatggattc catatagcgc agcagggaca gactggcatt tatgtcgggc
     3841 gaaccgtcgt ccactcccgg aagaacatgg gaatggacat cggtcatacc cttcattaaa
     3901 ccagaattaa tcaaattgta tttggacttg aatataccaa acatcctact tcttttttgg
     3961 ggggatttta ggatttcttt ctgaacagcc gtttccagca tgattcggaa ccatccacat
     4021 aaccatagcc gtagccgtaa ccatatccat agcctccgta tccgcctgtc tttactatgg
     4081 ccccgttaag taccaacgac atgttgttca gttgtccgct gcgataaatt ttttccactt
     4141 ccggtaacat gcggcggtcc agtttgccaa cccgtaccac gaaaatggtc aggtcggcta
     4201 tgcggttggt aatggcggca tcggccacca ctcctacagg cacattgtcg acaaagatat
     4261 agtcataacg gttgcgcagt tcggttatca gtacttccag ttgttcgctg agcaatagct
     4321 ctgacgggtt gggggcgatg ggaccggccg gaatgaaatc cagattttca cagatctcgt
     4381 tgtgcttgat gatttcatcc gttgtggcct tgcctgccag aaaagaggtc attccttttt
     4441 cctttgtgtg gaggcgggta tgtgaagtca aagtcccttt acggatatcc atgtcaatca
     4501 ggatgacctt cttgtcggtt tgcgcgaagc tggctgccag attgctggat acgtatgtct
     4561 tgccggcacc cggtccgaac gagctgaaag tgacgacttg catgttcttt gacttgacac
     4621 gcataaaatc catgttggtg cgtattatgc ggaaggcttc cgatacaatg tcacgccctt
     4681 gggcacggac agcgatgcca tgtgccgttt ctttattctc tgttttccct ttggatgaat
     4741 ccttgggtat ttcgcccagg aaaggaacgg ttacagcatc ctcgatgtcc ttgcggttgc
     4801 gtatacgggt atcgaagaac aggaacaata gcaggacaat tgccggcagg gcgattcctt
     4861 tcatgacacc tgccatgatc atgctgcgtc cgttgggaga aatcggagca tcccctcctc
     4921 cagcaggatc gagcacacgg gcgtcagttt cggtggtggc ctggctcagc gcattttctt
     4981 cgcgtttgtt cagcagatag aggtaaagtt cctctttgat gcgttgctga cgttcgatag
     5041 aaagcatttg ctgctgttgt ctaggtatgt tggttacccg ccactgggct tctccggccc
     5101 tgcttcgtgc ctcgttcagt ttcacgtcga tgctgacaat catattgtcg atggcccgga
     5161 tgatattctg ccgcatggca atcagattct tgttcagttc ctggacgatg ggattcttgt
     5221 cgctgcttcc ttctatcagt ttgtcccgtt tcaacttgtt ggcattatag gccgttatct
     5281 gggtttcaat gttgatgtcg gctatgccgg tgtttgaagg gataagctcg gtttctttgg
     5341 acgggtccac caggtagctc ttgatgtagc gtgccatgcg tgcctgtaat tccagttcct
     5401 gagtggtcga actgtactgc cgtttgtctg acatggacat ggaagcggct gaaccgatat
     5461 cgatgatgtc attgttctgt ttgtaggact gaagttcgtt ttccacgcct cccagttctt
     5521 tttcgatgat gaccagacgc tcgttgatga agctggaggt attgatggct atctggttct
     5581 tgtctttgat agtctcttca ttatacactg taatcagcat attgagcaca tcttcggcac
     5641 gggcggtgga gtaatcacgg agtgacaggt agaggatgga ggcgtcattc tcagcttggc
     5701 tgatgttcag gttgcttctg aataggctgg ccattgtgtc cgtactctgc cggcgtatcg
     5761 taatcggtgt gttgaaccac ttgtctgtat aatataaggt gggtgagacc actatttttc
     5821 ctacgggcga ctggatagtg tcacccagat tggccgtcag cgttatacct gtggcgtctg
     5881 tcgagaaatc ggacaaccgg acttgcttcc tgttcagggt tctgactgtc aggctgaaat
     5941 caagatggtc ttcttcttcc ggaaacgaga ctttgacagg ggcttgtgta taaagttcct
     6001 cctcacgcaa gtcatccatg atgaggtagc atacattggc gtgaagacgg ttcaccacat
     6061 cgcgcatgag tttgtgtgac tggaattgca ggatctcatt ggatacgttg gtatatgaat
     6121 aggtgttaaa acggtccagc ccgcggccga tgttgtttga ataggcgtcc tttatcatga
     6181 cggtggccga ccgtgaatag ataaagggaa gtttggcata ttgataccat gcgtatccgc
     6241 cgaacaaact gacagacagt ataaaccagt accagttgga caacaggtac atgacgatgt
     6301 caatggggtt gatgttgaat cctccgccac ttgtggcctt gtctcccgac aagtcttttt
     6361 gttcactcat tcttatcatg tcgtttcttt ttttatttgg tagttaacaa caccagtgag
     6421 gtgattgtgg tgataaagga caggatcata ctccacgtgc tcagttttct ctgggcctgt
     6481 tcggtggcct tcatgttggt gggttctacg taaacgatgt cattctgttg caggtaatag
     6541 taaggcgatg tgaagatgtc tttactgcgg atgtcgtgga acaggattcg tcgcttgttc
     6601 ccatattcgc ggatgacggc gatacggtcc agacgggagc ggggagtcag gtctccggcc
     6661 atggcaagag cctccagaag agtgatgcgg tcgcctttca cttcaaaggt tcctacatgt
     6721 ccaacttctc ccagcacgga aaatttgaag ttaaggaaat tgacggtgac cataggatct
     6781 ttcagcaatt cttcgttgat cagtcgtttc ttgatctgtt cggttaactg gcggcgggtc
     6841 agtccttcca catgcagttg tcccagcacg ggaaagtcta tattcccgtt gatgtccact
     6901 aaataacctt tttctttttc gtcacttaat gctcccactt cattgttgga aatggttccg
     6961 tccgcttcta cggaataact tctgcttccg gacatattga aaggtaggga cagttccggg
     7021 tttttgctgt tcacaataat gctcagtctg tcatccctat ggatgatggc ttcatatttc
     7081 tggaccatag ggtattcctg tagttcatcc atatcttgta aatagacaaa atctttgcgt
     7141 gaggcgcacg aactaaaaat gaccattgcc agcaggcagg ccagcttgat tgttttatcc
     7201 attgttttat aattaattgt tttttattct tttatatgaa tgacttggtc acatcgctcc
     7261 atcagtcgtg gatcgtgtgt cacaaatatt aaggtgttat ttttgcccca ttgcagcaaa
     7321 ttgtccatga ggcgtgtggt ggtcccggtg tcaagagccg atgatgcctc gtcaaacagc
     7381 cagatccgcc caggacgcaa cagtgcgcgg gcaatcgcga tccgttgggc ttgtccttca
     7441 gacaggccat atccatgttc cccgattcta gtatccagtc cttccggcag gctgaacaca
     7501 aattcagcgc aggccagccg gatgacttta tgcagagtct cttcgtctac tcccggacta
     7561 cccagccata aattctcacg tatggtaccg ctcagcaacg tgtttccttg gggtacatag
     7621 acgaagttga tgcgtaaatc gggggtcaca ctgagtgttc gcccgtcatc agtcgttaaa
     7681 tcgatacggc ctttttccgg atagaccaaa gccagtatca gccggataat ggtcgtcttt
     7741 cctgttccgg taggtccggc tatggcggtg gaatttcccg gatgaaaggt agcagtaaac
     7801 cggtcgagca ccggctgtcc ctcttcatac ccaaaagaca cttcccggaa gtccagtgtc
     7861 agcggctggt ctatgtagac agggtgctcg tccggttcca catcttcaaa gagggccatc
     7921 agccgttcca cggaagtcca tcctcgtacc aggctgggag ggatggatat tagccctaga
     7981 aaaggtccct gtacctgtcc gaccagttga agaaaggctg tcattgttcc gaatgttatt
     8041 tcgtggttat gtagttggaa tattccccat aggaacgcac acaagtagcc tccgccgaat
     8101 gtgattccca tcacgccttg tgtgaaggtg gagaacttga tctgttccat tcctaatttg
     8161 aacaactttt cttgtgtctc atgcagcttc tgcttccggt agccggtagc cccgagcgag
     8221 cggaccagaa tccgtttgga cagattctcc tgcatgacgg tgcccatctc gctgttcatc
     8281 tctttttggg cgcggctcag ttcccggacc ttccggaaat agattttcga taataagaca
     8341 agaggggtcg ctcccagtat gaaccaggcc aaacgggcgt caagaatcca caaatagagg
     8401 aaagagcctg tcagctgcaa gccggtaacc agcaggttgg gcaaaattcc cattcccatt
     8461 cctaatactt cggaggcgtc actaccaatg cgggtgagca ggtctcccgt gtgccatttt
     8521 cccgctcctt tccatgaaca catcatcagg gcgtcggaca gcgaattttg catgcggatg
     8581 ctgatgcgca tattaatttt gccaaaaatc caaggagata caagttttat ccccatacct
     8641 gacaggaagg ataagactac tattgtggct accaggtaaa tattcccttt ctgtgctccg
     8701 gtagccacat cgatgatcca tttggacatg gccacattga ccagcgacat gactactccg
     8761 aaaatacccg aaaagacaga gaagctgatg agccagtggt atccttctgt tacctgcata
     8821 acccatttga aagctttccg tcctaattga tatgtattgc tcagattctt ccgtgtgagc
     8881 ttctgcaaaa actttttcag caattttttc atttcccttt tatcatttcc ttgaagcgta
     8941 agagggctaa tccggacagc caccagaaag tttcatcaaa ggcatagcct gacgataagt
     9001 gcattttgtg aaagacccgc ttcaacgtgt atcgtttgtt cgcccatttc ccggagggac
     9061 gttcaccgta acgttcgtct ccatgtccaa aattgccact ttcccagatc tcctgcatta
     9121 acttatccgg acagagactg gtactgaatg gtaaaaggtc ggccggcacg ccaagatatt
     9181 ttattaatag ggcataaagc aactggttcc accggtgaat gtgccattta tggcagatac
     9241 gctccagttc gtttttgttt gtaacagaat gcaacgcgtt aaaagccatg gctacatcac
     9301 acaattgtcg tagtccgatc ccttcattga taagatgctt cagtatgtgg gtggaaagta
     9361 atagatgatt cgcttcgctc ggaagtttgc cctggctgtt ggcaaagact tccgcttccc
     9421 attggcggat tttcttttgg aggaaagggt tgtgcaactc gatcagcctg ctgtgatgtt
     9481 caaccagaac tctgtttatc agacaggaag cctcaccgtt ggctcccctt tttaccggta
     9541 atcctaattt ttccatccgt tggttggcct cttcggtttg tgcctcgttt ccgaaccaca
     9601 gatcgatgtc tccggctatg cgatgttccg gatgtgggta gaagccggct aaccctatcc
     9661 cttttagcaa caggagaggg atagaaggtg gctgtgcata aatttgttgc aggcctttaa
     9721 gtgtttcccc gtgttgccgg ttcacccgtt ccaaggtgtc aacttccacc atccagccaa
     9781 gtaatacctt ccggggaggt acggcttcat ccggcaacag gcggatgccg tcgtaaataa
     9841 tgccttgtac ggtttgtttt cttgccatgc tgtgaatttc attccattcc ttttcatcca
     9901 gaggaaaaag ggcggaacag tcttcctgcc ggtcccacag tccttgcctt agcaaaagca
     9961 tgaaagcctt ttgtaatggg gctgagatca tctttttgtc ttattctatg gctaaaccgg
    10021 tttctaacca ttgtcggcac agctcgttgg catcgttccg ggctgtatct ttatttactt
    10081 catattcatt gcacagcagt gctccggctt catctgccgt gaattccttg ttctccaatt
    10141 gtttccataa ccaggcggct gtctcattca tggaatagac ctgtgccata tccatggctt
    10201 ctgaaaatgg gttgacaatc atatattctc cacctacttg gcgaagaatt aaattaggat
    10261 tgagtctcat tgtctttata ttattgcatt atcctattat agttaaaatt acatagacct
    10321 tcacaggcag atgtaatggg gaataaaatg taagttcatt tattatcctc tgataatata
    10381 gggtcttgaa cttacttgat ctaacatttt ttacagatcc ggcgcttctc gcgaagaaaa
    10441 cggatctttc ttctaacatt tcttattgtc ttgtttgtca tatctgaatt gaacaggttg
    10501 ctgttcacca gtttataccc gtgggacgga ccatgccggc ttgcagcagc tgcatgataa
    10561 atcctgcggc atcttgcgat gcggtgtcct tgtctacttc gtattcctcc agaattaact
    10621 gtaccagatg gctgaagctt tctgtctctt cgatatgctc ccagataaat tctcctgttc
    10681 cggtcagggt gaccattccg ttgaactccc gggcggtctg tccggaagga accagtacga
    10741 tttctccggc tatgtttcgt ttgatgaatt ctttggttct tttcatcttt tgaaaaagcg
    10801 gtatgtttta atgatggttt cgcgtaaagg aattatgttc agccatacgt gggcgaagaa
    10861 tttccaccgg aaattttccg gaactatcca ttcccctttc cgcttcacct tggtgacgac
    10921 ggcgaaaatc tgttctctct gaattgggcc ttcgatgaca gtctgggcgt caccgataag
    10981 ataatattct tcttttttaa cattataaat acggtgcatg acatattcac cgttgctccg
    11041 ctgatagaac accatatctc ctttccggag ttcaccggag ggtctttcca ggcagatgtg
    11101 gtctcttgcg tggatcaaga atggagccat gctgctgccc gaaatgatca tgctcacctg
    11161 ctttccttcc tcaataaggg tacgcagcat ggatatgtat tcttttgtat cgacaacttt
    11221 cataatgggg tgtattccat ttatcggata attcccagtt cagtcagata ccgatgtagg
    11281 gtgaaggctg cttccggatt catgttgcac gcataggtgc tgatgcttgt ctgtccggtc
    11341 aaaaccagca gatcgtcgag tgctttgcga gtgagcttcg gattccacca gttgattgta
    11401 acctgagagc agagagcctt gaaatgcttc aagactgtct ggggacggat ggcgttatcg
    11461 ggtgcttgtt cgatgaagac gatggtcttc aacgggtggc gttcattgtg gcagataccg
    11521 ctggaaccgc atacaggcca tcccgttatc tcgtagccgc cgtttggaac aggacagagc
    11581 agggcacggt cgccattgag tacccgggtg tcgggaatat gccggcacca cagggcggca
    11641 tgtgttgatt tgccaatgcc gctgggaccg ctgaacagga tggcttgccc acgataatcc
    11701 agaaaggcac aatgcagtat gtagcatccc cgggcagaca aaggacgttc cagacaaagg
    11761 caggaaatga acagggtatc tgtttgcagt tctcttttca gtccttcgat gaaatagatg
    11821 tcggcattcc tttcgtcttt ttcctgatag agcgcatagc aggcgttcag atttcctata
    11881 gccagcaggc gtgtttcccg ttcttccttt cggaagatca cgatgtcgtt gcgtcggaat
    11941 atggcctgcc agtcgttgga cggcaaaggc agacggccga caaaatggaa tgtatagtgc
    12001 cggtctgctc ttttatcagc gggtttacgg tcgaggaaca gacggctgtt aacaggaatt
    12061 tcctgttctg tcactcccga caattcaatc gtcagcgggc cgatattcag tctcacaatc
    12121 ttcggttttt agtgtgttac ggagggataa tccataatga tctgttcttt ggctttcgcc
    12181 atctggcaaa gatagtccat gtttccggtg attgtctttt cacagtgtgc ggcggcatag
    12241 catacattgc atacgggacg aaggtggcaa ccctcgcatt cggtatggga taccagttcc
    12301 tttgcttcct ctaaaagtag ccgccatgcg gttgtcatcg gaaccttttt taggttaacg
    12361 gccggctggt ccatcatcac acagggggtg aggatgcctt gccagttgat ccagcatgaa
    12421 ctcttggcgg ctctgcactc caaagagcag gcttgggttc cttccacaag ggcaagcgta
    12481 tattttaaat tgtgcatgta tcgtgccatg tcattccctt ttttgtactc cacatattgc
    12541 atctcgatgc gggccgcctt gtcggcatcc agcctttcag ctggaatgtt acgcagactt
    12601 ccgcattcgg ggcgggagag gggaaacatg tatgagttaa cttctgccgg aatgtccagc
    12661 tgtcgggtca gacggatgat ctcgtcgtaa tccttttcat tctttcgtac gatacttacg
    12721 ttcagtttca catcgatgcc tgcctttttc aaccgtttca gggcttccac gcacagggtg
    12781 tatccttgtg gattgtggca caagcgtccg taggtttctc tactgcttcc atacaaggtg
    12841 acgtttatcc gccgcggctt gtgggtctgc aagatgcgta ccatttcgtt gtcgataagt
    12901 gtgccgttcg tattgagagt taggatgaat cccatttcgc gcagccgggt gtacagctcc
    12961 ttgaagtgtg ggtagagcat cggttcacct ccggtgagga ggatgaagag tgtacccatg
    13021 tcctgaagtt gttccgccca gtcgagccat tgttgcaaag gtaacaatcc tccgtgccgt
    13081 tccaccacgt tgcgttcggt gtgtatgaag cacatgtcac agttgagcgt acaggtagga
    13141 gtcagctcga agttggcagt gatcgggaca tggttctgat tggctttgtt caccaatgcc
    13201 cgttccacag gatttatgtc ttgcagggat tccaagggag taatgtttgt ttatatctta
    13261 tttacaaatt gtttcgcttg atagacagat gatggtattc tcattattta ccccataaag
    13321 tatatgttaa ccatccatac ccggttgcta tacaatagtc tattgttaag tgattagaat
    13381 gggctgtgta agttgtatga ttactgatca tgctgggtga agatttagat aattacagct
    13441 cgtgtgaatg tgaaagttaa aggttcccta taacctattc gctaaaaaaa ctactggata
    13501 ggttataagg gaaaaccaat attttcatta aaagctcaag actatcatga atgattacct
    13561 ataataattt gatctagttt ataaacaatg atagaatttc ctttggtctt ataagcgaat
    13621 aagcgttctt tacttgggtc ttcaaaaaca tattgacctt tttcaccatt gggtaatgca
    13681 ccactgttgt cgcatgtata tcgattggag ttaatttgtt cattggtgtc taaaattcca
    13741 ttattgtttt tgtctatcca aaaatgtgaa tcacttgaat aaggtgtagc attaggctta
    13801 ggttgccagc taatatctgg actacatgct gccacatatt cttgtggaac aaactcttca
    13861 ctaaccatta aaggtttctg ataacttttc tttttcatat ctcaattatt ttaaaaaatt
    13921 ctttttatta aggaaaggaa tacgcttcga aaagcgtttc ctttttcctt tgttagaaag
    13981 atatctgaaa taatgagata ttgcgatttg aatctccttg aggattatgt aactaaaata
    14041 ttaagaaaca ttgtgatgca atgtttcatc aatatgctgt gttacatgaa cattgttgta
    14101 attgaaaaca gggattgcat tatgttcaaa cggtcttaca acaaaagcat ttatatgagg
    14161 ttttgttgta gattcatatt tttcattgca agcagtattg aaatattcat atttgtcaat
    14221 tcccggatca tattgttgat tttcatttgt atccaaatat accatgccac ttatgtcaca
    14281 ataacctaca taagaagtag gattttcgca cgctgccaca tattcattcg gtacaaactc
    14341 ctcgccgata agcgttggtt ttgcatacac tttctttttc attctatctc tttctttttt
    14401 gattcctgtt ccgggggaag ggagatcaga aaagacttga ggcaaagtcg tgagttgagt
    14461 tccagaggaa ctatggtaaa agaaaatttg aaataactga tatattgcga tttagcattt
    14521 ataatatcat tctttcattt tccttttcat tacactaata ctttgtagct caagcgatgt
    14581 cctgacttag ttcctctgga actataattt ttttataaac tctcttattg aagtataaaa
    14641 aagtgcattg aaaaaactga atggacttag gaatgatttg gacggcctat aatttgagta
    14701 attttggatg tgatttttcc tgatcctgaa tgatagtaag tgcctgttcc attaggatct
    14761 acacttatcc atttaacaga aggtatcaca gttcctattg aaagttcttc attcaaatta
    14821 aaaccgttta aatcaatatt agaaattgaa tttccagtct tgtttcctgt ttcccatcct
    14881 tgtgcttgag cacctcttac ctcaactgtt gtagtagcac aaggggctcc gtgcccatct
    14941 tggccttttt tccctttctc acaatagaaa agggcatcat aatcataaca actagctaca
    15001 tattcttgag gtatgaaaac ttctgattcc aatataggct ttatgtattt cttcttttcc
    15061 attttttttt gattaagttc ttgagagact atggt
//
