LOCUS       gnlProkkaHLBHOPLF_278   6613 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HLBHOPLF_278.
ACCESSION   gnlProkkaHLBHOPLF_278
VERSION     gnlProkkaHLBHOPLF_278
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:28:03
            Original ID  :: gnl|Prokka|HLBHOPLF_278
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6613
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6613
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1335:5609]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1336..5609
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..6613
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6613
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             39..1322
                     /locus_tag="ctg278_1"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             1336..2034
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 7e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             2054..3355
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_3"
                     /sec_met_domain="CTP_transf_like (E-value: 7.6e-13,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 5.5e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.8e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3367..4503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 9e-23, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4500..5609
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 3.7e-34.
                     Score: 110.0. Matches aSDomain:
                     nrpspksdomains_ctg278_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 79.7; E-value:
                     3.4e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg278_5"
                     /sec_met_domain="Aminotran_5 (E-value: 2.7e-32, bitscore:
                     100.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDSTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAKMSLNNK"
     aSDomain        4590..5393
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg278_5_Aminotran_5.1"
                     /evalue="3.70E-34"
                     /label="ctg278_5_Aminotran_5.1"
                     /locus_tag="ctg278_5"
                     /protein_end="298"
                     /protein_start="30"
                     /score="110.0"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDSTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             5626..6612
                     /NRPS_PKS="Domain: NAD_binding_4 (8-140). E-value: 3.2e-08.
                     Score: 24.8. Matches aSDomain:
                     nrpspksdomains_ctg278_6_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 99.3;
                     E-value: 4.7e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg278_6"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.5e-105,
                     bitscore: 341.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.8e-11, bitscore:
                     29.9, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKDKVLMITGGTGSFGNAVLKHFINSDLKEIRIFSRDEKKQEDM
                     RIEYKNDKLNFIIGNVRDFDSINNAMAGVDYVFHAAALKQVPSCEFYPMQAIRTNLYGA
                     ENVLEAAARNNVKKVVVLSTDKAAYPINAMGMTKALMEKLAISKARDARVEANNGIICA
                     TRYGNVMCSRGSIIPLFIKQIKEGLPLTVTEPRMTRFMMSLDDAVDLVLFAFQNAEPGD
                     LFVQKAPAATIHDLAIAVKEIFNANNEIRIIGPRHGEKMYETLCTKEEMSKATDMGSFY
                     RIPADFRDLNYTKYLQKDGPRLVDHEYNSENTQRLSLDELKNLLLSLD"
     aSDomain        5650..6045
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg278_6_NAD_binding_4.1"
                     /evalue="3.20E-08"
                     /label="ctg278_6_NAD_binding_4.1"
                     /locus_tag="ctg278_6"
                     /protein_end="140"
                     /protein_start="8"
                     /score="24.8"
                     /tool="antismash"
                     /translation="ITGGTGSFGNAVLKHFINSDLKEIRIFSRDEKKQEDMRIEYKNDK
                     LNFIIGNVRDFDSINNAMAGVDYVFHAAALKQVPSCEFYPMQAIRTNLYGAENVLEAAA
                     RNNVKKVVVLSTDKAAYPINAMGMTKAL"
ORIGIN
        1 ttggaagcta atccatatcc gtacagcgaa ctacacgaat gattcgttcc tttctttccc
       61 gttctcccct ttacgttttg gctctctatg ccagcgtttt gatttttctg gtttatactt
      121 gtgcctatgc ctaccgtaag ccatttaccg cagccattta tgaaggtgag attctttggg
      181 gattcgatgt caaaatcctg tatgtccttt ctgagattat cggctacgcc ctttccaagt
      241 tcatcggtgt tcgtattctg ccttcgatga aagcgggtca ccgcatctat tatataatag
      301 ggctgcttac tttttccgaa gttgctttgt tgggttttgc acttcttccg gttcctttga
      361 aggtgtgttc tatttttctg agcggtcttc ccctgggtat gatctggggt gtcattttta
      421 gctatatcga aggacgtcgt atcagtgaaa tattgaatgt cgggctgagc gttgctttga
      481 tagtctcttc cggtttggtg aaaaccttgg gacaattcgt gatggataat ttgcatgtgt
      541 cggaatattg gatgcctttt accaccggtt tgttggtata ccctgttatg ttgctttgca
      601 gctggcttct caatcagatt ccggctccca atgagcaaga tatcatacag cgtaccaaac
      661 gtgctccgat ggatggtaaa gacaggcgta aatttttgag gcaattcttc tggggaatct
      721 gcatgctggt tgttttttac ggtgccctga ccgtgttccg tgagcttcgt gactctttcg
      781 ctgccgatat ttggaaggag ctccatattg agggtgcaat gatctttact cagacagagg
      841 ttcccattgc cgtttttgtc cttgtactga tgttcctgat tgtgtttgtc cgtaataacc
      901 gtttggctct taatatcatt tattgcattg ccgttacagg cggttcctta atggtttttt
      961 ccacattgct ttatgtgtac ggttttcttt ctcctatttg gtggatgatt ctttccggtc
     1021 ttggtctgta tatggggtat attcctttca cttacctgat agaacgcctg attgcttccc
     1081 ttagggtggt tagtacggct gtttttatta tttatttggc cgattctttc ggctatctgg
     1141 gcactacggg tgtgtttatg gtcaagaact tcgtttctgc tgacatttcc tggactgtca
     1201 tgctaatgcg tactgccctt ttttcaggat ttgtttctgt cctgtcgatt tttgcgattt
     1261 actgttattt caagcaacaa ttgaattcac ttatattaat tccctctgaa attcatgatt
     1321 aaaacagcaa tgatcatggc tgccggtctt ggtacccgct tcgggcatta taccgagctt
     1381 gtgcccaaag gttttgtgga ggttggtgga aaacctatga ttatccgctc tatcgaaacc
     1441 cttctttcct gcggtatcga acgtatcatc ctcggtacgg gttataaaaa agaggcttat
     1501 gaagcccttc aggcggattt cccccagata gagacctgtt tcagtccccg ttatgccgat
     1561 actaacagta tgtacactct gtacaatacg cgtgacgtga taggcgatga cagtttcctg
     1621 ctgcttgaat cggaccttgt ttttgaacgc aaggccatcc tctcgctact ggatgacgaa
     1681 ttcccggatg tgatgcttgt ctcttctctg accaagttcc aggatcagta ttatgtggaa
     1741 tatgaccgca atcacatcct tacttcctgt tcggtagaca agaacgccct tgaggcaaaa
     1801 ggcgagctgg tcggtatcca taaactttcc aatactttct accgccggat gtgcgccgat
     1861 tatgcgacca tcctggagtc ccagcctaaa ctgggttacg agtacgaact gctccgcatg
     1921 tcccgttccg tttcccctgt ccgtgtgctc agggtggagg gtcttaaatg gtatgaaatc
     1981 gatgatgaag ccgacctttc gtatgccgag gagcacatca tccgctattg ttaaaaacaa
     2041 atcttttcca tatatgaaca agaaaatcta tgtcggtatg accgcggata tcatgcatcc
     2101 ggggctgatc catattattc atgaagctac taaatacggt gatgtcatcg tcggtctgct
     2161 gacggacaag gccatcgccg aacacaaacg cctcccttac cttacctatg atcagcgtaa
     2221 ggaggttgtt gagaatatca agggggtttt tgaggttgtt ccccaggagg actggagcta
     2281 tgttccgaat ctggaaaaac tcaagcctga ctatatcatc cacggcgacg actggaaaac
     2341 gggcccgttg cgcgaggtgc gcgaacaggt ttttgaggtg atgaacgccc aggggggcaa
     2401 ggtaatcgag atcccttata cccggggcat caactcctcc tcgctcgaca aggatatcaa
     2461 ggcgatcggg actacccctg acgtacgtct taagtccctc cgccgcctga tccaggccaa
     2521 gcctgtggtc cgtatcctgg aggctcacga cggtctttgc ggtctgatta ttgagaatct
     2581 tgaagtccag aagggtgata agcgcgaggt ctttgacggc atgtggtcca gcagcctgac
     2641 cgactccacg agtaagggta aaccggatat tgaagcggtc gaccttacca cccgtttaca
     2701 ggacctgaac aatatccttg aatgcaccac caagcctatt atttttgatg gagacacggg
     2761 tggcaagatc gaacactttg tctttactgt gcgcactctg gaacgtcacg gcatttctgc
     2821 ggtaatcatt gaagataaag tcggtctgaa gaagaattcc ctttttggta ctgacgctat
     2881 ccagactcag gatagtatcg agggtttctg cgataagatc agagcaggga agaatgccca
     2941 ggtcaccggt gactttatga tcattgcgcg tatcgaaagc cttattgccg gcaaacccat
     3001 gagtgacgcc ctcgaacgtg cttatgccta tgtacaggcg ggtgcggacg gcatcatgat
     3061 ccacagcaag gataagtcgg gtgaggatat ccgtgagttc tgccggactt tccgcaaaga
     3121 atacgcccat gttcccattg tcgttgttcc gacgacttat gaccatgtgc acgaatccga
     3181 acttcacgaa tggggtgcca acgtagtcat ttacgccaac caccttctcc gtgccgctta
     3241 cccggccatg atgaacgtgg ccaggaccat ccttgaaaac gagcgcgccg aggaggtccg
     3301 tccgctttgt atgcctatca aggaaattct ggaattgatt ccgggcacta aataaatcag
     3361 acggttatgg taagtgtaga aaagatatac gatacgttcc ttcatcacgg tgttgacttc
     3421 tttacgggtg ttcccgattc ccttttgaag aatatttgcg cctatatcac ggatcatgct
     3481 ccgcgtggta agcatatcat cgccgccaat gaaggttccg cggtgggcat tgcctgcggt
     3541 tattatatgg cttccggcaa cgttcctttg gtttatatgc agaactccgg tctgggaaat
     3601 acggtgaatc ccctcttgtc ccttgcggac gagaaagtgt acagccttcc tcttcttttg
     3661 ctggtcggct ggcgcggtga gcccggcacg aaagacgaac cccagcataa gaagcagggc
     3721 gaggttaccc ttgatcttct gaaagccatg aaaattcctt ttataattct ggatacggat
     3781 gaagacgagg ccctggcgca gatccatgac gcggttgtct cggcgaagag ccggtcgatt
     3841 ccccatgcga ttgtcatccg taaagatacg tttggaaaat ataaattgcg tcaggaagcc
     3901 ttgaatgact atcctctgtc ccgcgaggag gcgctaatgc aggttgtcga ccacctcggg
     3961 gacaatgaca ttgtggtttc caccacgggc aagctctccc gtgagctttt cgagtaccgc
     4021 gaatcgaaag ggcaggggca cgcaagggat ttcctaactg tgggttccat ggggcacagt
     4081 tcttccattg ccctgggggt tgcccttgag aagcctgacc gccgtgtcta ctgtcttgac
     4141 ggtgacggtg cctttatcat gcacatgggt gctgtcagca atatcggcga tctttctccc
     4201 aagaattaca ggcacgtcct tttcaacaac ggtgcccatg aatctgtcgg cggtcaaccc
     4261 acgctcggtt tccgtctgga tatcgcctcg atagcgaaag gttgcggtta tgcgcatgta
     4321 ctgactgcct ccgacaagga agggctttcg tgtgcgcttg agaagctgtc cggcctgtcc
     4381 ggcccggttc ttcttgaaat taaggtccgg atcgattcac gtgatgatct gggtcgccct
     4441 acgactactc cggtagagaa taaagagcat tttatggcat ttttaaaaga tacgcattca
     4501 tgaatatcga aagaaagatc cttttgaatc cgggtcccgc caccacgacg gatacggtga
     4561 agctggcgca ggttgttccc gatatctgtc cgcgtgagaa agagtttgcg ggtatgatga
     4621 aacagttacg tgacgacctg gtccgcgttg cgcatggaga cctctccaaa catacggccg
     4681 tcctgttttg cggctcgggt acgatcaata tcgatatctg cctgaactct cttcttcctg
     4741 cggataagaa agttctggtt gtcaataacg gtgcctacag cacccgtgcg gtggaagtct
     4801 gcgaatatta cggtcttccc catatcgatt tgaagttttc cgtttacgaa cttcccgacc
     4861 tgtcggtaat cgaaaagacg ctttccgaca atccggacat cgctttggtc tataccacgc
     4921 accatgaaac gggtacgggt atcttgaacc ccatccgtga gatcggaaaa atagcccatt
     4981 cgcacggtgc cgtttttgtt gtcgacagca cttcctccct gggtatgatt ccttttgata
     5041 tcggaaagga taatgttgac ttttgtatgg cttcggctca gaaaggcctt caggccatga
     5101 cgggtctttc ctttatcata ggtgatgaat ccctgatacg tgcttcaagg gattatccga
     5161 aacgctccta ctattgtaac ctctatttac aatacgatta ctttgagaag acgggtgaga
     5221 tgcattttac tcctcctgtt caaaccgttt acgctgcccg tcaggctctt gatgaatatt
     5281 ttgcagtagg tgaagaggct aaattcgccc gtcacaagag ggtctttgaa gccatccata
     5341 aaggtttgca agagcttggt cttcagtatg cgatcaaacg tgaatggcag tcgggtcttg
     5401 ttgtttctgt attgtatcct gatgatcccc tctgggattt tgataaggtt catgattact
     5461 gctatgaacg tggctttacg atctacccgg gtaagatttc cacaacgaat acattccggc
     5521 tttgtgcgtt gggagagatt gatgtggagg atattgagag gttctttgag gtgatgaggg
     5581 aggcgaaaat gagtttgaat aataaatagg ataatagtat gatatatgtt taaagataaa
     5641 gttctaatga ttactggggg aacaggctct tttggtaatg ctgttttaaa acattttatt
     5701 aattctgatt taaaagaaat cagaatattc agtcgtgatg aaaagaagca ggaagacatg
     5761 cgcattgaat ataaaaacga taaattaaat ttcattatcg gtaatgtgcg tgattttgat
     5821 agtattaaca atgcaatggc aggcgttgat tatgttttcc atgctgctgc attaaaacaa
     5881 gtaccttctt gtgaatttta tccaatgcag gctattcgta ctaacttgta tggcgctgag
     5941 aatgtattgg aggctgctgc tcgtaataat gttaaaaaag ttgttgtttt gagtaccgat
     6001 aaggctgctt atcctataaa tgctatggga atgacaaaag ccttaatgga aaagttggct
     6061 atatctaaag caagggatgc tcgtgtagaa gctaataatg gtataatctg cgccactcgt
     6121 tatggaaatg taatgtgttc tcgtggttct attatacctt tatttataaa acagataaaa
     6181 gaaggtttac cattgactgt tacagagcca agaatgactc gttttatgat gtctttagat
     6241 gatgcagtag atttagtcct ttttgcattt cagaatgcag aaccgggtga tttatttgtt
     6301 cagaaagcac cggctgctac tattcatgac ctcgcaatag ctgtcaagga aatatttaat
     6361 gcaaataatg agattcggat tattggacca cggcatggcg agaagatgta tgaaactctt
     6421 tgtacgaaag aggagatgtc taaggccaca gatatgggtt cattttatcg tatccctgca
     6481 gattttcgtg atttaaatta taccaaatat ttgcaaaagg atggaccacg cttggttgat
     6541 catgagtata attcggaaaa tactcaacgt ttaagcctag atgagcttaa aaatcttttg
     6601 ttaagtcttg att
//
