LOCUS       gnlProkkaHLBHOPLF_332   5380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HLBHOPLF_332.
ACCESSION   gnlProkkaHLBHOPLF_332
VERSION     gnlProkkaHLBHOPLF_332
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:28:03
            Original ID  :: gnl|Prokka|HLBHOPLF_332
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5380
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2022
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 162.2; E-value: 4.6e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg332_1"
                     /transl_table=11
                     /translation="MTLVTASQQVETPEEAPVPVTLITEEMIRAIHARCLRDVLIAYVP
                     GISGLSSNEEMNLAMRGVYSPEQENILIMQDGQRLNSYITNAVSPDYGISLAKVKQIEV
                     LRGPASSLYGSVALTAVINIVTKDGVDVRNGSISVSAGNRGQLAADLLLGKHDMNMDFM
                     AWFSLYRATGESVFVPAEKQYALYPRDGFIRLDNYSGFPAMDGGIKLQRGNLLFSFSMN
                     YAKKRQPYSMWLFSSPYSYERFRTFDGSGPGYSRWSAREQAVYSHTWQRITFSTAFYTD
                     WNKNVHYETSGDTLQDYPIFPNYDYQPIIYPTRGAFQYIRWMDFNVGFNGRVNYAYDWG
                     KLGKGNMLGGVEWNRYTLYDSEYLEGMNFKEIVRTWIEKRLYTGHEMNTDAFLQIKHNL
                     HKNWIVNAGIRYDYKRRSNKRTLQAFSPRLSLIYLRNGLNIKASYSRAFVDAPYYYRNN
                     EMDTYSGGENLQAEYLSSYQVTCAYHHSPSHIDVECNLFYNRASHFLFTQPETRVYENA
                     GSLDMGGVEVVARYKADRLSLDGNLCFQKVLNYTNFFVTDGSVNNVPGFSMNLVANYFL
                     LKKKVQSWSAHLKLNCSSHCYTQVSVLEDGLNGDATNYTVRLPGYAVFSFTTRYKYKRI
                     EGSLGIENLFNNRYECGGATVPIRQKGRWISASILYNF"
     protocluster    1..5380
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2034:4464]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2035..4464
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..5380
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5380
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             2035..4464
                     /NRPS_PKS="Domain: AMP-binding (12-401). E-value: 2.4e-83.
                     Score: 271.8. Matches aSDomain:
                     nrpspksdomains_ctg332_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (509-568). E-value: 2.7e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg332_2_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     259.9; E-value: 6.2e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_2"
                     /sec_met_domain="AMP-binding (E-value: 6e-89, bitscore:
                     286.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-11, bitscore:
                     32.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNIQENLSRSLSTWGDKPAVVAKDGTVSYQMLERYSANIAQSI
                     RQRLSVTDPSGLRNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAEN
                     ADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNP
                     KGVRISYRNLDTFTRNLIDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLIL
                     AGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNR
                     LKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGAT
                     GELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVK
                     IRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLR
                     AELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELKYVPPVHPGEVILCGILKEM
                     LGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRRLLLVPRQEP
                     IYWYRQQNLKKPVIILVCGSAYFNHLYFNLADRLYPKYDFLVVDAIYDHFNKVATDIPE
                     LLEYYVRTVQPMIRERTVYALTGFCMGAELAVGLAEMLHRSMGIMPKVFALDGQAWQNP
                     ALCQNYPLLVFPGDTDEMVRERNEIINIYFRTTPNLIYQGEVIVLLSGFFHQQAGLSPE
                     ESWTEENYRIFRTEYDNCERLWNKYYPNAPVLRLPADHWHFLEGESLEQLITVFLK"
     aSDomain        2071..3237
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg332_2_AMP-binding.1"
                     /evalue="2.40E-83"
                     /label="ctg332_2_AMP-binding.1"
                     /locus_tag="ctg332_2"
                     /protein_end="401"
                     /protein_start="12"
                     /score="271.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LSTWGDKPAVVAKDGTVSYQMLERYSANIAQSIRQRLSVTDPSGL
                     RNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSN
                     EVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNPKGVRISYRNLDT
                     FTRNLIDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLILAGEDERRDISLL
                     DELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVY
                     GPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSL
                     GYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     aSModule        2071..3738
                     /complete
                     /domains="nrpspksdomains_ctg332_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg332_2_PP-binding.1"
                     /locus_tags="ctg332_2"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2263..2304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg332_2_0001"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg332_2"
                     /protein_end="90"
                     /protein_start="76"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS_motif       2485..2541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg332_2_0002"
                     /evalue="1.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg332_2"
                     /protein_end="169"
                     /protein_start="150"
                     /score="26.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       3043..3129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg332_2_0003"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg332_2"
                     /protein_end="365"
                     /protein_start="336"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       3202..3264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg332_2_0004"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg332_2"
                     /protein_end="410"
                     /protein_start="389"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        3562..3738
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg332_2_PP-binding.1"
                     /evalue="2.70E-10"
                     /label="ctg332_2_PP-binding.1"
                     /locus_tag="ctg332_2"
                     /protein_end="568"
                     /protein_start="509"
                     /score="32.6"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     CDS             4469..5362
                     /locus_tag="ctg332_3"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLTLVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGVISIMILNKTLQQTGVLHHDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNTVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMNLVRRVQTEYSSFIKDILYYIPLAETISSRKKLNYDQLMDYTLSQYDYLQGQ
                     EGESTASGAIIPRVMEIDPSDDIRKELERIMEERLTGRTYLYHLKSDLAEATHQLIIYE
                     ENRINSILHKPEREMN"
ORIGIN
        1 gtaactctgg tcacagcctc acaacaggta gagaccccgg aagaagctcc ggtgcctgtt
       61 actttaatta cggaggagat gatacgggct atccatgccc ggtgcctgcg ggatgtactg
      121 atagcttatg tgcccggtat atccggtttg tcttccaatg aagagatgaa tctggctatg
      181 cgcggggtat attctcccga acaggagaac atattgatta tgcaggatgg acaacgtctg
      241 aacagttata ttactaatgc tgtttcgccg gattatggta ttagcctggc aaaagtcaaa
      301 caaatagagg tgctgcgcgg accggcttct tcgctttatg gcagtgtggc tttgacagcc
      361 gtgattaata tagttactaa agacggggtg gatgttcgta atggttccat atctgtcagt
      421 gccggtaatc ggggccagtt ggctgctgac ctgctattgg gaaagcacga catgaacatg
      481 gactttatgg catggttctc cttgtaccgt gcaacgggag aatcggtttt tgtcccggcc
      541 gaaaaacaat atgctcttta ccccagggac ggattcatcc gtctggacaa ttattcggga
      601 tttcctgcca tggatggagg aattaaattg caacgtggaa atttgctttt tagtttcagt
      661 atgaattacg cgaagaaaag gcaaccttat agcatgtggc tcttttcttc tccatattct
      721 tatgagcggt ttcgtacttt tgacggttcc ggcccgggat attccagatg gtcggcaaga
      781 gaacaggctg tttatagcca cacgtggcag cggatcactt tcagtaccgc attttatacc
      841 gattggaata aaaacgtaca ttatgaaacc tcgggagata ctttacaaga ctatcctatt
      901 tttcctaact atgattatca acctattatt tatccgactc gcggagcatt tcaatacatc
      961 cgctggatgg attttaacgt aggctttaat gggcgtgtaa actatgccta tgattggggg
     1021 aagctgggga aaggcaatat gcttggcggt gtggaatgga atcggtatac gctttatgat
     1081 tccgagtatt tggaaggtat gaattttaaa gagatcgtca ggacgtggat cgaaaaacga
     1141 ctttacacgg gacacgagat gaacacggat gcctttctcc agattaaaca caacctgcat
     1201 aaaaattgga ttgtcaatgc cggcatcagg tatgactata aacggcgaag taataagcgg
     1261 acattacagg ctttttctcc ccgtctgtca ctaatttatc tcaggaacgg attaaatatc
     1321 aaagccagtt attccagagc atttgtcgat gcgccctatt attacagaaa caatgaaatg
     1381 gatacctatt cgggtggcga aaatctgcaa gctgaatatc taagttcata tcaggtgact
     1441 tgtgcttatc atcattcacc ttcacatata gatgtagagt gtaatttatt ttataatcgg
     1501 gcgtcccatt ttctgttcac acagccggaa acacgtgttt atgaaaatgc cggttctctg
     1561 gatatgggag gtgtcgaggt tgttgcccgt tataaggcag accgactgag cctggatgga
     1621 aacctgtgtt ttcagaaagt attgaattat accaattttt ttgttaccga tggatctgtg
     1681 aataacgtac ccggcttttc tatgaatctt gtagcaaact actttttact taaaaagaaa
     1741 gtacagagct ggtctgccca tttaaaattg aattgcagta gccactgcta cactcaggta
     1801 agtgtattgg aagatggact caatggagat gcgacgaatt acacagtccg tttgcccggt
     1861 tatgctgtct tttctttcac taccagatat aagtataaaa ggatagaagg cagtctgggc
     1921 attgagaatc ttttcaataa ccgatatgaa tgcggaggag cgactgttcc tatccgccag
     1981 aaaggaaggt ggatttccgc cagtatattg tataatttct aaatcaaact aataatgaaa
     2041 acaaacattc aagaaaatct ttctcgatca ctctctacct ggggtgacaa accggcggtc
     2101 gttgcaaaag acggtaccgt ctcttatcaa atgctggaac gttactctgc caatatagca
     2161 caatctatcc gtcaacgttt atcggtaact gatccgtccg gacttcggaa tatctgtatc
     2221 ggagtttgta tggaacgaaa caaaacttta gtacctgcca ttctggctat tttccggtta
     2281 ggggcaactt atttaccgat agatccctcg ctgccggata atcgtaaacg gtatatggct
     2341 gaaaatgcgg atatggtttt gttgttgacc gattcatcga atgaagtagg tggaattccg
     2401 tccgtccgcc aactttacct gaatggggag caactatccg aaccggttgt tggtgactat
     2461 actgaagttc ttcccgatga ttgcgcctat attatatata cttccggaac aacaggcaat
     2521 cccaaaggtg tacgtattag ttatcggaat ctggatacat ttacgaggaa tctgatagat
     2581 aagaaattgt atcatttgtc tgatccggca aacaggtatc tggcgtttgc gagtatcagt
     2641 tttgatgctt ccatattaga actgatgatg tgtattccgg tcggaggaac attgatcctg
     2701 gccggtgagg acgaacgcag agatatttct ttactagacg aactgatcag gcgcgagaag
     2761 gtgaatattg ctttttttcc tccttcgttg ctgggcatgt ttgccgacct tgactttcca
     2821 tcctttaaga ctctgctctt tggtgcggag gctattggtg aaaagttatt taacaggctg
     2881 aaacagcagc cttaccggtt gatgaatgta tatggaccga cagagaatac cgtactcagt
     2941 accatacgga ttgtaggcaa agatacgtcg tatgacgata ttggctatcc gctcaaggga
     3001 actgtctgtt atgttttgtc tgaaaacctc caacagacaa ctcttggggc tacaggagaa
     3061 ctttgcttgg gaggacctca ggtttcgctg ggatatattg ggagtgttca gctgaatgaa
     3121 aaatcattca tctcgtacga tggagaacgg ttgtacagga caggtgactt ggtacagcag
     3181 caaccggacg gttcaatacg gtttatcggg cgaaaagata ctcaggtcaa aatacgtggc
     3241 tttcgtatcg aattgactga aatagcagaa cgattgaata gagatccgga cgtggagaga
     3301 gcccacgtag tagttgttga gcggaatggg cgtcaattat tgggagctta tttgcaaccc
     3361 tcagtctccg gtaactttca tccggaagag gtcaaagaac gtttgcgtgc agaacttcct
     3421 tactacatga tacccaattt atggcaggtg gtagatcatt ttcagcgtac tataaatgat
     3481 aagattgatg tccgggcgct cccggctttt acttcattgg agttgaagta tgttcctcct
     3541 gttcatccgg gggaggttat cttatgtgga attttgaagg aaatgttagg tttgcctcaa
     3601 gtcagtgttg aggccgattt gattgatgat ctgggattaa cttcactgga tatgttgagg
     3661 cttgttaccg aggccaataa aaaaggatgt cccatcaacg tatctgcagt ttatactgcc
     3721 cgtaatctgc gccgattatt gctcgttccg cggcaagaac ctatctattg gtacaggcag
     3781 caaaacctga agaaacccgt aatcattctg gtttgtggat ctgcctattt taatcatttg
     3841 tactttaatt tggccgaccg cctttatccc aaatatgact ttctagttgt agatgctatc
     3901 tacgatcatt ttaataaagt ggccacggat attccggaac tgttggaata ttatgtccgg
     3961 acggttcagc caatgatccg ggagcgtacc gtctatgcgc ttaccggctt ctgtatggga
     4021 gctgaactgg ctgtcggcct ggccgaaatg ttacatcgct ccatggggat aatgccaaaa
     4081 gtttttgctc tggatggaca ggcttggcaa aatccggctc tctgtcaaaa ttatcctttg
     4141 ttggtatttc ccggagatac cgatgaaatg gtacgtgaac ggaacgaaat cataaatatt
     4201 tattttcgaa ccactcctaa tctgatttat cagggagagg ttattgtttt gctgtccgga
     4261 ttcttccatc aacaggcggg attgtctcct gaagagtcgt ggacggagga aaattatcgt
     4321 atattccgga cagaatatga caattgcgaa agattatgga ataaatatta tccgaacgct
     4381 cctgttttgc gattgccggc agatcattgg cactttttag aaggggaatc attggaacaa
     4441 ttaataactg tgtttttgaa gtagatttat gcagactgaa aacttcactt taggtaagaa
     4501 agagcttctt attttgcttg gcttgactct tgtactgcct tttccaatca attgggcatt
     4561 aatcgaactg aatccgttga ctctgatggc gggtgcagac gatgtgccca cctggattgg
     4621 tttcggcggc agttatattg gaggaatcat cggaggggtc atctcgatta tgattctgaa
     4681 caagacactt cagcagacag gtgtacttca tcacgatttg aaactcctgc agttagatac
     4741 cataatttat actcagcaac aagattggtt taccggtttc aaacaagaac tggcagagaa
     4801 tctcaaatct attgatttgt atgtgttgaa tacggttgtt tcgtctatat ccatgaaaaa
     4861 ctatgcatat gccaaagagg tgttgacaga aatcaataaa gggctcgaat atcagatggt
     4921 tgccgcatcc ttttctttca cttctacgca tttatcatcc gaagaaaaaa agtatatgaa
     4981 tctggtacgc cgcgtacaga ctgaatatag ctcttttatc aaggatattc tttactatat
     5041 tcctttggca gaaacgatat cttccaggaa aaaactaaac tatgatcagc tgatggacta
     5101 tactttgtcc caatatgatt atttgcaagg tcaggaaggg gagtctacag cttcgggagc
     5161 catcataccg cgtgttatgg aaatcgatcc atctgatgat atacggaaag aactagaacg
     5221 gataatggaa gaaagattaa ccggtcgtac ctatttgtat cacctgaagt cagatcttgc
     5281 agaggctacg catcaattaa ttatttatga agagaaccgt ataaactcta ttctgcataa
     5341 acctgagaga gaaatgaatt gacatatatt aatataatat
//
