LOCUS       gnlProkkaHBPKLCAG_9    15110 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBPKLCAG_9.
ACCESSION   gnlProkkaHBPKLCAG_9
VERSION     gnlProkkaHBPKLCAG_9
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 12:14:28
            Original ID  :: gnl|Prokka|HBPKLCAG_9
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 38975
            Orig. end    :: 54085
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15110
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11410]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11410
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15110
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15110
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2282..2842
                     /locus_tag="ctg9_37"
                     /transl_table=11
                     /translation="MAKKRNYENDEAYKNFRLEDYLPSMNRREPEAKISEPEQDTATEE
                     TALFPPLDAPDISAIQAAASETIRPDGQDVQEDEAGTDDADEEDVEIASVETEIPVKRT
                     VTGRISSKQRRLSLEEYRSTYLQVPRITDRKPVFVSGEVRDRLDEIVRRLGGRGMSVSG
                     LVENLARQHFASYGNDIEQWRKL"
     CDS             3426..4355
                     /locus_tag="ctg9_38"
                     /transl_table=11
                     /translation="MIAKIMKGSDFKGVVYYILNDEKGTQIIDADGLFLENNDTIAQGF
                     TGQARMNPRVTKAVGHIALSFSKEDAPRLNNAVMARIAREYMERMGIKDTQYIIGRHFD
                     KEHPHVHIAFNRIDNNGKTISDRNDRFRSERICKELIKKYGLHFANGKEQVKVERLREP
                     DKTRYGLYQILKAEVGRCKDWNTLLERLKRQGVDVQFKYKGQTNEIQGIVFTMNGYRFN
                     GSKIDRAFSYSKIDAALSRNNYEERQMRPQPHPQSNRDEISQISDSGGNLIEGSLGLFS
                     PSNQPEEQQPYDPYLRNKKKKKQRKINW"
     CDS             4358..5026
                     /locus_tag="ctg9_39"
                     /transl_table=11
                     /translation="MADNNNVFILFEEIKTTLNGIKSKLEELPDVADRQPQIGNDKPDL
                     SPIKEAVVETTKAQSEEIKDLLARQWEAYAQVTTVILKRIGFLEEQFKVPDVQQQLPRQ
                     DHIHRHSFDIKSSKVFSFVVGIGVICALSLWGNIGQWQSKRQYADDALKFRAIRSWGGC
                     NANDVLWLNKVFDIRRDEKAIEWVRKQADGYGTTLKAVSDSIMQEDMKGKSPTDNLKSD
                     "
     CDS             5030..6226
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 71.5; E-value: 1.8e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg9_40"
                     /transl_table=11
                     /translation="MASVKVKFRPSTVVDKEGTIYYQVIHNRVIRQIKTDYRVFREEWN
                     EKSGVVILSANGRTDILRSIKERIGWDLKRLKAIIGRMENSGNVFTADSIVEEYQEATR
                     EQSFFRFMEGVIVRLKLLNKERTAENYAATLKSFMRFREDSDVLLDEFSSDLMMEYEAY
                     MKAQDITMNTVSFYMRILRAVYNRAVEKGLTEQRNPFRHVYTGIDKTVKRAIPLKAIKQ
                     IKELDLSMNPSLEFARDMFLFSFYTRGMSFIDMAYLKKKDLQNGILSYRRRKTGQQLFI
                     RWEKCMQEIVDKYQRNGTDYLLPIINKVGNEQRQYRNALRLVNNKLKEIAIIVGLQVNL
                     TMYVSRHSWASIAKNKNVPLSVISEGMGHDSEATTQIYLASLDNSLVDKANEMILKNL"
     CDS             6639..7940
                     /locus_tag="ctg9_41"
                     /transl_table=11
                     /translation="MRLEKWFISNLDDSQRKIIIQSITDDIIVQGAAGSGKTNLAIHRA
                     LQAKNKGSYAIVIFTVALKRMIAYGMQALGLDKERIAYEWAWTHRGFDLTGDVYWEKGN
                     RNTLYLVNDLSVRKFERTEKDKTTYGIDFADWVDYKFYSAFGRRVSWFREIPYTSGFSV
                     TNTEKFELIPSGTMYKQSEDRIDYLIIDEAQDFNVSDYQSRMIAHRGKSLSLFGDSVQQ
                     MNFNGSSIDEIAKTLGYKRFSLDYNYRLPKTIAKVAQQIQSVKVDLMTNNMKDGGNSDY
                     PNYPKPIITKYSSKEKELEGILNRIKMEDLDDVAILVPDESDVREVNDFLTQRGINTQV
                     HYRTGNVVPFRTINTLDFSNNDLPCILTYYAAKGSEFDNVFVPFANEANTCKRNAFYVA
                     CTRSSRNLYISYTGKKTSFLKDVSKEYVVEIENN"
     CDS             7945..9711
                     /locus_tag="ctg9_42"
                     /transl_table=11
                     /translation="MFYYIGINSWNLLESFVSESISPFSFYQVRGYGNNLSRYIDGTNE
                     RVNYLILSTKEIEGDYVLKVNEEILDKSNITPVKKSKTLFTYSKTIYYKKGAVAFLFSS
                     NDLLESFVAESQILFEVKCIEKYKSEFVINTGKTKKPLVTDRIANSFSFQRHEYIVQDN
                     VYDRLKGMIVAYTHAMVFAEDPHEQRLSCQLRDLKNSFAGLNTQVMVSESAVSNAGEYM
                     SLIKKAKAAYNGIIKTKTNLFDILIQLFSEIIKLSKARADELSENKQVSGTDRIENLMA
                     QKEELENKLYNIEYRDGISDLVEELNSIKNQELNNGIKMGKTREYFKKGTLEYERKQYL
                     KNKIKKYEEDNDEYKSIKQDICNIKQQITNIDTGASVYDTTLGALFVRVSEIMNELISK
                     AKTSSKNNGQVNYSCLSLRNSAVSIDVNASVEEKAFLDIIINEALKSEKRVLSDDVVLN
                     LIVESANKYKCREYANTENGKLILRSLREFWAYKHNQCSSFSIPNNLVVLKSLMAFFIK
                     PFGFDQIERYVQNKGVENKEYGYMLRGAFIGYAAFPKTFTDALYGDKNIYIPMDEYLTT
                     IHKQVEAQYPCD"
     CDS             9750..9941
                     /locus_tag="ctg9_43"
                     /transl_table=11
                     /translation="MGVLKLSVIEEQNKQLKNKLRIAGQKGNVVRISNCYCPCECFIRE
                     GEITMCDDVASAGSWNID"
     CDS             10001..11410
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_44"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.7e-08, bitscore: 25.5, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.3e-10, bitscore: 31.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESIAFQTQHSNYYLYSPSTKTILPLPKDLYDIISNGKNKETETL
                     RQLREYGYIDDFTSSLDACITGNAIQNALINLSQIIFETTTLCNLRCEYCCYSEGYDTF
                     DSRRGVLGNLKFETAKSIIDYLVVLFQREAKSDAPKEPFAISFYGGEPLVNFDVIRQIV
                     EYAKCVEFRNRSLFFTMTTNAMLLSKHADFLSHHNFKMLISLDGNKEHDSYRKTPNGSP
                     SFDIVMKNLMDVESMFPKWFATFRYNAVFSNISDVRNIVEWFKSQLNTTPNFSPVHTPT
                     KDTKNGDRILSMLKTFEIPEDIALEHGLITQNPLFNRILLFSTRLLNNSFNKETDLLID
                     DNTDNKILPTGTCIPFSKRMFVSYDGKIHPCEKVNRDSPLGFIDNNGCVRIDCNDIASR
                     FMKRITEFSFLCKKCYMQFCCTKCSFCYSNGKCEEFTSKNKFAKLLSEAVSYIESHPNI
                     IEILENNIIIK"
     CDS             11407..12549
                     /locus_tag="ctg9_45"
                     /transl_table=11
                     /translation="MNRLYIFFPHCYIKATSTELLIYDTITFKGVYLKDVVLANHNIDR
                     LNRFGYIEENCDTKFLLQKIATNHFGYYIQYDGFMPYIPERKLRIATSLQKEKKALGYN
                     LTSYTNMMLTSLTLLLNNTIFTYLNAFSYQQLEYPDTNCVEIDMEKISLQLRSFCLEKI
                     ILSGELSYGKLEKFLEYARDRNIQVIYRIHYLAYPFSYIKEILRKFDSLVIELLVDSHT
                     PFHMLNFNEERLLYKYIITSISDVDKISKIGKDVILCPVFLDTKTITLQSQMIMTKDEI
                     LQSCHTLKECYVKEYINPSCFGHLTINFNGEVCCLNERIESLRDMDLPYIINKWVGSQG
                     CLWYLARNKRCCCKECAIQVLCPSVSIYELLNIYKCPCTV"
     CDS             complement(12714..13757)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 69.8; E-value: 5.7e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg9_46"
                     /transl_table=11
                     /translation="MKKEVRIKEPVRIRTKRLSNGCESIYLDIYMDGRRRYEFLKLYII
                     PEHTRTDKDLNQSTMKLASAVKAQRIIELQNGVYGFNHQQEKKDIMLIDYIKYLADKDI
                     EKTSRKVSMYTLIYHLQHYDKMGIRLRQVDKKYILGFVEYLKTATQKHCKSVKNISANT
                     QVHYYKVFHHCLNSAVIDEIITSNPMDKIKNEEKPKRRRTERAFLTIDELKILSQTDFH
                     NATLKKAFLFSCFCGLRHSDIVALTWGNLKKGKVGKMELHMTQQKTQEILSLPLSKEAL
                     KQLPVRGKVPDTEKVFKGLISLGRTNEILPKWAAKAGIQKHITFHQRRHYPNSFPLKTN
                     DLQRIVS"
     CDS             14288..15082
                     /locus_tag="ctg9_47"
                     /transl_table=11
                     /translation="MYKVDITIYPELSLKNLVITQIYQVLFNLSPAIEVSFWKGMKFTA
                     QMVIPVYNDGYASRYDKLHPGFLELSQTVRLPYNFWATLAIGSFNNSRYGIDFNLIHHF
                     KDERFSIEGRIGYTGTGYWEGFTMHYGTKMRATWSLGGSFYWPRYNVELNARVEQYLLK
                     EKAVRVEAIRHFRYASIGFYAMKAKDVKANGGFRFQIALPPYRYKRKGYIPRITPSNNM
                     GMSYNAGNEQYYYKTYRSAPDDNIMKNNSFNPYFIKSELLNF"
ORIGIN
        1 gcggatattg tcgctgtata acacgaccga tgacgagaag cccgtgtttc ctcttcccaa
       61 ccgtgatgcc ctatggtttg aggttcacga gttgggaata accataggga aagaggaaaa
      121 cttgacctat caccaaagtc ggcacagttt cggaacattt ttgatttcgg cagatatacc
      181 gattgagagt atcgccaaga tgatgggaca ctccaatatt cggacgacac agggttatgc
      241 acggataacc gatgataaaa tctcaaagga catggacaag ctgatggaac gcagaaagat
      301 gcaatttacc tgcgaaaaaa caaataacag taaataaaca atatcaattc agcatattat
      361 gaaaagagga ataataacaa tcagtgaaac gggtgctgtc attatgccga ccgcacccgt
      421 gtggatgacg caatttgaga ttgccgacct gttcggtgtg ttctcctgcg atgtccgcaa
      481 ggcgatacgg gtaatctaca agaacaagga actgaatgaa gccgatacaa tgcgatatat
      541 cagacaacca gacggtatca gctgtgacac ttacaacctt gaaatggtcg tagccgttgc
      601 attcaggata tgcagtaaag aaagtattct gttcagacgg tttgtaataa gtgaaatctg
      661 cgccaccaag aaagggaatc cgttcacact gttcttctct tgtggcagag gtaacaaccg
      721 atggtatagt tgaagtccat cccgccagcc acttgttccc aatgtcggat gcaaaggtag
      781 cgtgtggctc tgacggcatt ggcaaggtca ggcggcagag ccgttccgtg gacaatcttc
      841 ctctttcaga gcgtattctc cacggaaacc ttgccactgc ccgccacacg caaaagaggc
      901 atccgtgggc ggaaacaagc gactgacggg aaatcagaag atagaaagga acggcttaca
      961 gacgaagcaa gatattgatg cttcatccgt aagccgttcc tttttgccga gagttcattg
     1021 ctccgcaatc atggggcaga cggcaaactg cgctccttca agaaaatcag gttgccctct
     1081 gtcggtaggc ggagcggtat ccgtcagcca gcatcctttc gatgtccgat tcacggtaga
     1141 ggattttgcc gcctaattgt atgtagggta tgcgaccctc gttgcggtag tcctgaagcg
     1201 tacggcggct cactttcagc cgtgccgaca cctccttgtc ggtgaagaaa cgctcgccgc
     1261 ctaatgtcgg gcggtagtga gcggtcagat gctctacatt gtccagcagc cggtcaaggc
     1321 tgcccatgaa atggattatc cactcgttgt ctctgttaat cagttcgttc atattacttt
     1381 ggatttagtg gaattattgt tgttactcta ttcggttatc agattgtcct gcccttgaac
     1441 ttcgcttcct ttcgtttgtc ctccacgatg gaaacgatac gcttcacatc ttcgggacgg
     1501 tagtaggttt tgtgattgat ttggctatat gccaatgtgc cgttatcccg aagagtctgc
     1561 aacgtgcgtg ggctgatgtt gagcatccgg cacacgtcct gattatccat ccactcgctc
     1621 attgtctttt ctccatgccg ccggcagacg gcatccatac ggcgtacaaa atggtcgaac
     1681 ttggcgacca tcgcctcaaa ggtctttctt tcgattgata cgatttccat attgtctttc
     1741 ttttaattgt tactgtttct tttgccgcaa aggaatacag aatcagctgt tctgcaatgg
     1801 atttctccaa agtggcagcg tgttgcgccg atacggtagc ctttgtccgg gttaccgttt
     1861 ttcttttagt cgttatcatt cctttttccg caaagaaata tacaatccgt tacccgacaa
     1921 tggattttcc ggaagtggca gcatgtggca cagggtggta gcggttggct taggcacagc
     1981 tcaccgatag cccgatccgt tcagccctta attccgatat ttaataaaga agtcacagtc
     2041 aaaataagag cttaattctg aaattgcccg tgcctgaacc tttaccccct ggggcattca
     2101 catccggcaa atcggtgaaa tcctcaccga tgtttctatc gccatacggc aaaaccgcac
     2161 aaaattgcct aagagaatcc gaatgcttga cctattgaat cacaggcagt tattttgctt
     2221 ccgacaatcg gtcgactatg cgcatacaga ccacgagtat taacttttaa aatgtaacaa
     2281 gatggcaaag aaaagaaatt acgagaacga tgaagcgtac aagaacttca gactggaaga
     2341 ctatctgcct tccatgaaca gacgtgagcc ggaagcaaag atttccgagc cggagcaaga
     2401 cacagccacg gaagagacgg cactctttcc tccgttggat gcaccggaca tatccgcaat
     2461 acaggctgcg gcttcagaaa caatccgacc tgacgggcag gatgtacagg aggatgaagc
     2521 tggaaccgac gatgccgatg aagaggatgt ggagatcgct tcggttgaaa cggaaatacc
     2581 cgttaaacgg actgttaccg gacgcatcag cagcaaacaa cgcagactct ctttggagga
     2641 gtatcgctcc acgtatctgc aagttcccag aatcacagac cgcaagcctg tgttcgtcag
     2701 cggtgaggtg cgtgacaggc tggatgagat agtccgccgt ctcggaggca gggggatgag
     2761 cgtgtcgggg ctggtcgaaa acctcgcccg tcagcacttc gcctcctacg gaaacgacat
     2821 cgaacagtgg cgtaaattgt aggaattaag acaagaccga cggggtgtgt tcggggtatc
     2881 tttcatagat gctcaaaatc acttgtaacg aagtttggag ggagcaagtt tatgtttcgg
     2941 gcagaccgaa accgcttgcc ccgctccaaa cctcgcaggg aaggcacatc ccgttggtct
     3001 attcttcatg taatcattgc acttagtgaa tacattaaat tttaggatat tatggacaac
     3061 gaaaagagaa aggacaacgg acgggaacga gccaacaagg gcggtcgccc cgtcaaggga
     3121 gctgccgaga aactgaaata ccgtatcacg gtaaagatgg caacggagga ctactacctg
     3181 ttgaagtcca aggcgaagtc ggcaggaatt tcagccagtg aatttatccg tggttgcatc
     3241 acgaaaggcg gagtgaaaga acggctctcg aaagagcacg gcgaccttat ccgcaaactg
     3301 tgcggcatgg cgaacaacct gaaccagttg gcgagaaaag cgaatgcgga gggctacact
     3361 tccgtgttca taccctgtcg cacactggtg atagagatag acaaccttgt aaaccggata
     3421 cgcctatgat agccaaaatc atgaaaggct cggacttcaa gggtgtggtt tactacattc
     3481 tgaacgatga aaaaggtact caaatcatag atgcggacgg cttatttttg gaaaataacg
     3541 acacgatagc gcagggattc accggtcagg cacggatgaa tccgagggtg acaaaggctg
     3601 tcgggcatat cgcattgagc ttctcaaagg aggatgcgcc acggctgaac aatgcggtca
     3661 tggctcggat agcccgtgag tatatggagc ggatgggcat caaggatacg caatacatca
     3721 tcgggcggca cttcgacaag gagcatccgc acgtgcatat agcgttcaac cgtatcgaca
     3781 ataacggcaa gaccatttcc gacaggaacg accgctttcg cagcgagcgc atctgcaagg
     3841 agcttatcaa aaaatacggg cttcactttg ccaatggtaa ggagcaagtg aaggtagagc
     3901 gtttgcgaga gccggacaag acgaggtacg ggctatatca aatcttgaag gcggaagtcg
     3961 gcagatgcaa ggattggaac accttgcttg aacggttgaa gcggcagggc gtcgatgtgc
     4021 agttcaagta caaggggcag acaaacgaaa ttcaaggtat agtctttacg atgaacggct
     4081 accgcttcaa cggctcgaag atagaccgcg ctttcagcta ttccaagatt gacgcggcat
     4141 tgagccgtaa caattacgag gaacgacaga tgcgaccgca accacatccg caatctaatc
     4201 gggacgagat aagccaaatt tcagatagtg gcggcaatct tatcgagggg tctttaggct
     4261 tgttttctcc aagcaatcaa ccggaggaac agcagcctta tgatccttat ttgagaaaca
     4321 agaaaaagaa gaaacaacgt aaaatcaatt ggtaactatg gcagacaata acaatgtatt
     4381 catcctcttt gaggaaatca agacaacctt aaatggcatc aaaagtaaat tggaagagtt
     4441 gcccgacgtg gcagaccgac agcctcaaat cgggaatgac aagccggatt tatccccgat
     4501 taaggaggct gttgtggaaa cgacaaaggc tcaatccgaa gagattaagg acttgttggc
     4561 aaggcaatgg gaggcttatg cacaggtgac aaccgtgatt ttgaagcgaa tcggtttcct
     4621 tgaagaacag tttaaagtac cggatgttca acagcaactg ccccgacagg atcatatcca
     4681 caggcacagc ttcgacatca aatcgagcaa ggtcttttct ttcgttgtgg ggattggtgt
     4741 gatatgcgcc ttgtccctgt ggggcaacat cggacaatgg cagtccaaac gtcagtatgc
     4801 cgatgatgcg ctgaagttcc gtgccatccg ctcttggggc ggatgcaatg ccaatgatgt
     4861 gctttggctg aacaaggtgt tcgacatccg ccgggacgaa aaagccatcg agtgggtacg
     4921 gaaacaggcg gacggatatg gcacgacttt gaaagccgtt tccgacagca tcatgcagga
     4981 agacatgaaa ggcaaatctc cgaccgataa ccttaaatcc gattgatata tggcatcggt
     5041 aaaggtcaag ttccgccctt cgactgtcgt agacaaggaa gggacaatat actaccaagt
     5101 catccataac cgagtaatcc gtcagataaa gacggattac cgggtgttca gggaggaatg
     5161 gaatgagaaa agcggtgtag taattctttc tgccaatgga agaacagata ttctacgttc
     5221 gataaaggaa cgtatcggat gggatttgaa gaggctgaaa gccatcattg gaagaatgga
     5281 aaacagcggt aatgttttca cggcagatag tattgtggag gaatatcaag aggccacaag
     5341 ggaacaatcc ttcttccggt tcatggaggg tgtcattgtt cgtctgaaac tgcttaacaa
     5401 ggaacggaca gcggagaatt atgcagccac gctaaaaagc ttcatgcgct tccgggaaga
     5461 tagcgatgtc ctgttggacg aatttagctc cgaccttatg atggaatatg aggcttacat
     5521 gaaggcgcag gatataacca tgaacacagt ctcattctat atgcgcatac tccgtgcggt
     5581 gtataatcgt gccgtggaga aaggactgac ggaacagcgc aatccattcc ggcacgtcta
     5641 tacaggcata gacaagaccg tgaaacgtgc cattccactg aaagccatta aacagattaa
     5701 ggaattggac ttgtccatga atccgtcatt ggagtttgca agggatatgt tcctcttctc
     5761 gttctataca cgtggaatgt cgttcattga catggcctac ttgaaaaaga aagacttaca
     5821 gaatggaatc ctttcttacc gcagacgcaa gacggggcaa cagcttttca tcaggtggga
     5881 gaagtgtatg caggaaatag tcgacaaata ccagagaaat gggactgatt acctgctgcc
     5941 tataatcaat aaggtgggta atgagcagcg acaataccgt aatgcactac gcctcgtcaa
     6001 taacaagcta aaagaaatag caataatcgt aggattgcaa gtgaatctca ctatgtatgt
     6061 cagccgccat tcttgggcaa gcatagcaaa gaacaagaat gtaccgcttt ccgtcatcag
     6121 cgagggaatg ggacatgatt ccgaggcgac tactcaaatc tatctggcat cattggacaa
     6181 ttctttggtg gacaaggcga acgagatgat attgaaaaat ctgtaggagt gtgtttagca
     6241 aaataggtta tctcttcgta agagagggat ttgtcggtgt aaaaatactc aaaatagcgc
     6301 aaatcaaaga atgtatcggg gagaaaatca actttttata tcaaaaaaca tagaaagaac
     6361 atagaaatgt ttagcaaaaa gataactatc atgatttgaa gtgttgattt ttagtacgtt
     6421 tctatcctaa tccctctctt acgaagagag ggagaaaaat tcgacgtaaa agataagaaa
     6481 tggaaaagaa aagtctttat attgtcatag gaatagttat gagcattgtg ttatgcgcat
     6541 tgagtggatg tggatatgat agaattggaa cttcttctga aaaaagtaag atccgtccaa
     6601 ttctcgttat agcctttctc taataaatcg gttaagttat gagattagaa aagtggttta
     6661 tttcaaactt ggatgattcg caaagaaaaa tcatcataca aagtataacc gatgatataa
     6721 tagtacaagg agcggctggt agtggaaaaa cgaatctcgc catccatcgt gctctacagg
     6781 caaaaaataa aggaagttat gctattgtca tttttaccgt ggccttgaag agaatgatag
     6841 catatggtat gcaggcactt ggtttagaca aggaacgtat agcatatgaa tgggcttgga
     6901 ctcaccgcgg tttcgatttg actggagatg tgtattggga gaaaggaaat agaaatacgc
     6961 tctatttggt aaatgattta agcgtcagaa aatttgaacg cacagaaaag gacaagacta
     7021 cctatggaat tgacttcgca gattgggttg attataagtt ctactctgcc tttggacgaa
     7081 gagttagttg gtttagagaa attccataca catcaggctt tagcgtgaca aatacagaaa
     7141 aatttgaact gattccaagt ggaaccatgt acaaacaatc tgaagaccgt attgattatc
     7201 tcatcatcga tgaagcgcaa gatttcaacg tatcagacta tcaatcaaga atgatagccc
     7261 atagaggaaa aagcctttcc ttgtttgggg attctgtaca acaaatgaac ttcaatggta
     7321 gttccattga tgaaattgct aaaactttgg gatataaacg tttctcgtta gattacaatt
     7381 atcgtttgcc aaagaccata gcaaaagtag ctcagcaaat tcaaagtgtc aaggtggatt
     7441 tgatgacaaa taacatgaaa gatggtggta atagcgacta tcctaattat ccaaaaccca
     7501 ttatcacgaa atactcttcc aaagagaaag agttagaagg catcttaaat aggataaaaa
     7561 tggaagattt ggacgatgtg gcaatcttgg ttcctgatga gagtgacgtg cgtgaagtaa
     7621 acgatttttt aacacaaaga gggataaata ctcaggtgca ttatcgaact ggaaatgtcg
     7681 ttccttttag gacaatcaac actttggatt tttcaaataa cgacctacca tgtattctta
     7741 catactatgc agcaaaaggg tctgaattcg acaatgtttt tgttccattt gctaatgagg
     7801 cgaatacctg taaaaggaat gctttctatg tagcatgtac tcgttcttca cgtaatcttt
     7861 atatttccta cacgggcaag aaaacatcat ttttaaaaga tgtatcgaag gaatatgttg
     7921 ttgaaataga aaataattag aaatatgttt tattatatag gcataaattc atggaactta
     7981 ctggagtcgt ttgtttcaga aagtatatct ccattctctt tctatcaagt aagaggatat
     8041 ggcaacaatt tgagccgtta tatagatgga acaaatgaaa gagttaacta tcttatcttg
     8101 tcaacaaagg aaatagaggg tgattacgta ttaaaagtca atgaggaaat tttggacaaa
     8161 tcaaatataa ctccagtcaa gaaaagtaaa accctattta catatagtaa aacaatttat
     8221 tacaaaaagg gtgctgtcgc ttttctgttc tcttcgaatg atttacttga atcttttgtt
     8281 gcagaatcac aaatattgtt tgaggtaaaa tgtatagaaa aatataaatc tgaattcgtg
     8341 ataaatacag gtaaaacaaa gaagcctttg gttactgata gaattgcgaa ttccttttct
     8401 tttcagcgtc atgaatacat tgtccaagac aatgtttatg atagattaaa gggaatgatt
     8461 gttgcataca cccatgcaat ggtatttgca gaggaccctc atgagcaacg actttcatgc
     8521 caattgcgag atttgaaaaa ttcatttgca ggattaaata cgcaagtaat ggtttctgaa
     8581 agtgcagttt cgaatgcagg tgaatatatg tcacttataa aaaaagccaa ggctgcatat
     8641 aacggaatca ttaagacaaa aacgaatttg ttcgacattc ttattcaatt gttctcagaa
     8701 atcataaaat tgtctaaggc gcgtgcggat gaactctcag aaaacaagca agtaagcggt
     8761 actgacagaa tagagaattt aatggctcaa aaagaagaat tagaaaataa gctttacaac
     8821 atagaatatc gtgatggcat ttctgatttg gttgaagaat taaactctat aaagaatcaa
     8881 gaactcaaca atggcatcaa gatgggtaaa acacgtgaat atttcaaaaa ggggactttg
     8941 gaatatgaac gcaaacaata tctcaaaaac aaaatcaaaa aatacgaaga agataatgac
     9001 gagtacaaat ccattaaaca agacatatgt aatataaaac agcagataac taacattgat
     9061 acaggagctt ctgtgtatga cacgactttg ggagcattgt ttgttcgtgt cagtgaaatt
     9121 atgaatgaac ttatcagtaa agcaaaaaca tcaagcaaaa ataatggtca agttaattat
     9181 tcatgcctat cgttaagaaa ctctgctgtg agtattgatg taaacgcttc tgttgaagag
     9241 aaagcgtttc ttgacattat tattaatgaa gctctaaaaa gtgagaaaag agtgttgtct
     9301 gacgatgtgg ttctgaacct catagtagaa tcagccaata aatacaagtg ccgagaatat
     9361 gcgaatacag aaaatggcaa gctaatactt cgtagtcttc gagagttttg ggcatacaag
     9421 cataatcaat gttcttcatt cagcatacca aataatctgg ttgtactgaa gtccttgatg
     9481 gcgttcttta ttaagccttt tggctttgac caaatagaac gatatgttca aaataaaggt
     9541 gtggaaaata aagagtacgg gtacatgcta agaggagcct ttatcggata cgcagctttc
     9601 ccaaaaactt ttaccgatgc tctttatggc gataagaata tttacattcc tatggatgaa
     9661 tatctaacaa caatacacaa acaggtcgaa gcgcaatacc cctgcgattg acttgtgaac
     9721 aatgaaatgg ggtttaaaaa gaaaaactta tgggagtatt aaaattgtct gttatagaag
     9781 aacagaacaa acaactcaaa aacaaattga gaattgcagg acaaaaaggc aatgttgttc
     9841 gcattagtaa ttgctattgt ccttgtgagt gcttcattag agaaggcgaa atcacaatgt
     9901 gtgatgacgt tgcctctgca ggaagttgga acattgatta aaatcactaa ttgaaggaga
     9961 gccattgttt tattactttg gctttcctta ttttaaattt atggagtcca ttgcttttca
    10021 aacccaacat agcaattatt atctgtatag tccatcaacg aagacgatat tgcctttgcc
    10081 caaagacctg tacgatatca tatcaaatgg taaaaataaa gagaccgaga cccttcgaca
    10141 attaagggaa tatggttaca tcgatgattt tacctcatcg ttagatgcat gcataacagg
    10201 caatgcaata caaaatgcat tgataaattt gtcccaaatc atattcgaaa cgacgacact
    10261 ctgtaacctc agatgcgagt attgctgtta tagcgaaggt tatgatacat ttgacagcag
    10321 aaggggcgtt ttggggaatc tgaaatttga aacagcaaaa agcatcattg actatttggt
    10381 cgttcttttt cagcgcgaag caaaatcgga tgcgcctaaa gagccttttg ccatcagctt
    10441 ttacggaggt gagccattgg taaactttga tgtcattcgt caaattgttg aatatgccaa
    10501 atgtgttgaa tttcgaaatc gttcactatt ttttacgatg acgacaaatg caatgctttt
    10561 atcaaagcat gccgactttt tgtcacatca taatttcaaa atgttgatta gccttgacgg
    10621 aaacaaagaa catgactctt atcgaaaaac ccctaatggc tccccatcgt tcgacatcgt
    10681 aatgaagaac ttaatggatg ttgaaagtat gttcccaaaa tggtttgcaa catttcgata
    10741 taatgccgtt ttttccaata taagtgacgt taggaatata gttgaatggt ttaaatctca
    10801 attaaatacg acaccaaatt ttagcccagt tcatactcct acaaaggaca caaaaaatgg
    10861 agataggata ttgtctatgc tcaaaacttt tgaaattcct gaagatattg cgttggagca
    10921 tggcttaatc actcaaaatc ctctttttaa tagaatattg ctatttagta caagactatt
    10981 gaataattca tttaataaag agacagactt actcatagat gacaatacag acaacaagat
    11041 actgccaaca ggtacctgta ttcctttctc aaaacgaatg ttcgtaagtt acgatgggaa
    11101 aatacatcca tgtgagaaag taaacaggga ttcaccatta ggatttatag acaacaatgg
    11161 atgtgtccgt attgattgca atgatattgc aagtagattc atgaaaagga ttacagaatt
    11221 ttcattcttg tgcaagaaat gctatatgca gttttgttgt acaaaatgtt ctttttgtta
    11281 tagcaatggt aagtgcgaag aatttacatc taagaataag tttgcaaagc tattgtcaga
    11341 ggctgtatca tacatagagt cacacccgaa tataatagaa attcttgaaa ataatattat
    11401 tataaaatga atagactgta tatatttttc ccacattgct atatcaaagc gacatcaacc
    11461 gaactgctca tatatgacac tataacgttc aaaggtgtat atctgaaaga cgttgtattg
    11521 gctaaccata atatagacag attaaaccga tttggctata tcgaggagaa ctgcgacacc
    11581 aagttcttgc tgcaaaagat agctactaac cactttggat attacatcca gtatgatggg
    11641 tttatgccat acatcccaga aagaaaatta aggattgcaa cttcactaca gaaggaaaag
    11701 aaggctttag gctataatct cacgtcatac acaaatatga tgctgacatc ccttacatta
    11761 ttactgaaca atacaatatt cacatatctt aatgcgttct cataccaaca attagaatac
    11821 ccagatacta attgtgtaga aattgacatg gaaaagattt ccctgcaact tcgttctttt
    11881 tgtttggaga aaatcatatt gtcaggagaa ttatcatatg gtaagttaga gaagtttctt
    11941 gaatatgcaa gagatcgaaa tatacaggtt atctaccgaa ttcattattt agcatatcct
    12001 ttttcttata ttaaagaaat cctacgtaaa tttgattcgc tggtaattga gttgttggta
    12061 gactctcaca cgccgtttca tatgctaaac tttaacgaag aaagattgct atataaatat
    12121 ataataacat cgatttctga tgtggacaaa atatcaaaga taggaaagga tgtaattctc
    12181 tgcccggtct ttttggatac aaagacaatt actttacagt cacaaatgat tatgactaaa
    12241 gatgaaattc ttcaatcatg ccatacacta aaagaatgtt atgtaaaaga gtatataaat
    12301 ccctcttgtt tcggccattt aactatcaat tttaatggtg aagtttgttg cttaaatgaa
    12361 agaatagaat ctttgcgaga tatggattta ccttacatta taaacaagtg ggttggttca
    12421 cagggctgtc tttggtatct tgcaagaaat aaaagatgtt gttgcaagga atgtgctatt
    12481 caagttctgt gcccatcggt ttcaatatat gaactgctaa acatatataa gtgcccttgt
    12541 acggtttagt ctaataaaag aaagaatcct ttcgtaaaca ggaatttcat cctctataac
    12601 agtttgtatt tcaaaaaaat aatgctacct ttgcatttga agccagcgtt cttttgattt
    12661 aatgcaaaac aaggtaagat acggaacttc gctcgtttcc aaatcgttac ctatcaagaa
    12721 acaattcttt gtaagtcgtt tgttttcaat gggaaagaat ttgggtaatg tcttctctga
    12781 tgaaaagtaa tatgcttttg aataccggct ttagcagccc atttgggtaa tatttcattg
    12841 gttcttccta aactgataag ccctttgaac actttctctg tatcaggtac ttttccgcgg
    12901 acaggaagtt gtttcaaagc ctccttgctc agaggaagag agaggatttc ctgagttttc
    12961 tgttgcgtca tatgcagctc cattttaccg acttttccct ttttcagatt tccccatgta
    13021 agtgccacta tatcactatg tctcagtcca caaaaacaac tgaatagaaa agcctttttt
    13081 aaagtcgcat tatgaaaatc tgtttgtgac aatattttca attcatcaat agtcagaaat
    13141 gcccgttcag tccttctccg cttaggcttt tcctcatttt ttatcttatc cattggattt
    13201 gaagttataa tttcatcaat tacagcacta ttcaggcaat gatgaaaaac cttataataa
    13261 tgaacttgag tattggcact tatattcttc acacttttac agtgtttctg agttgccgtc
    13321 ttcaagtatt caacaaagcc aagtatatac tttttatcta cctgtctgag cctgataccc
    13381 atcttatcat aatgctgaag atggtatatc agtgtataca tagacacttt ccttgaagtt
    13441 ttttctatat ccttgtctgc caaatacttg atataatcta tcagcattat atctttcttt
    13501 tcctgttgat ggttaaagcc gtatactcca ttctgcaatt ctataatcct ttgtgccttc
    13561 actgcactgg ccagtttcat ggtgctctga tttaaatctt tatccgtccg tgtatgctcg
    13621 ggtattatat atagctttaa aaattcatat cgtcttcttc catccatata aatatctaaa
    13681 tatatagact cacaaccgtt cgacagacgt ttagtcctga tcctgaccgg ttctttaatc
    13741 cttacttctt ttttcatatt atttgtttgt atgtttttag ttataaatat agacattatt
    13801 ctgttataag taacaaacag gtaacaaaag tccatgaaaa aagatttcta ataaaaagcg
    13861 atcagacaaa aaccggtttt caaaatccac tataattctg ataaccaaaa tattataaat
    13921 aaaacaaaga ttctttatga atcttaatta aagtagcagc tcagtaacag agatacttcc
    13981 atatagaagc aaccagccaa agtcctaata gaaccgaaaa atctactaaa acatcaatcc
    14041 aatgtatatc aatacattag gaaacgaagt aagtgatgtg atattctaca aatcaaacta
    14101 ctgattaccc gaaagaaagc catgccgtat tatcgttttg aataacaatg tgccgcaaat
    14161 atctctttat tatcagccat ctttcaaaga tagtacagta aatattagca gacaagactg
    14221 ggaagttagt tataatctgg gaaatagctg gaacaaagta aaaaggaata aaaaagcaaa
    14281 tagctctttg tacaaagtag atatcacaat atatccggaa ttatcactaa aaaacttggt
    14341 aatcacacag atttatcaag tgcttttcaa tttatcaccc gccatagaag tctctttctg
    14401 gaaagggatg aaattcacgg ctcaaatggt gattccggta tataatgacg gatatgccag
    14461 cagatacgat aaactacatc cgggtttcct tgaactatcg caaacagtcc gtctgcccta
    14521 taatttttgg gcaacattgg ctatcggtag ctttaataat agccgatatg gcatcgactt
    14581 caacctgatc caccacttta aagatgaacg tttcagtata gaaggccgca tcgggtatac
    14641 cggtacagga tattgggaag gttttactat gcattatgga acaaagatgc gggctacatg
    14701 gtcattggga ggaagctttt attggccacg ctataatgta gaattaaatg caagagttga
    14761 acaatatcta ttaaaggaga aagcagttag agtagaagca atccggcatt ttcgctatgc
    14821 ttccattgga ttctatgcaa tgaaagccaa agacgtgaaa gccaatggag gattccgttt
    14881 ccaaatagct ttaccccctt accgatataa acgcaaagga tatattcctc ggatcactcc
    14941 ttccaataat atgggaatgt cttataatgc gggaaatgaa caatattact ataagactta
    15001 tcgctcagca cctgacgata acataatgaa gaacaatagt tttaatccat attttataaa
    15061 atctgaatta ttaaattttt aattttattg agatgaaaat gaaaagtaaa
//
