LOCUS       c00466_gnlPro..        16328 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJOMKGMG_466.
ACCESSION   c00466_gnlPro..
VERSION     c00466_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:33:02
            Original ID  :: gnl|Prokka|JJOMKGMG_466
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16328
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16328
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8440:11911]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8441..11911
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16328
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16328
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             103..1146
                     /locus_tag="ctg466_1"
                     /transl_table=11
                     /translation="MANMKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGA
                     ASVAKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIV
                     GCTALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFF
                     TIFLSYTFAIAKRDGSMKEPEKEYLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVD
                     GASGIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFF
                     VLGCSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYT
                     AVLIYNL"
     CDS             1297..2433
                     /locus_tag="ctg466_2"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             2551..4485
                     /locus_tag="ctg466_3"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRTAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             4482..4940
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg466_4"
                     /sec_met_domain="CTP_transf_like (E-value: 6.3e-19,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             4963..6585
                     /locus_tag="ctg466_5"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(6668..7270)
                     /locus_tag="ctg466_6"
                     /transl_table=11
                     /translation="MKKAIFFVYFIYLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             7376..8278
                     /locus_tag="ctg466_7"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNSM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             8441..9139
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_8"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-129, bitscore:
                     419.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLSALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             9176..11122
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.7; E-value:
                     2.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_9"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.8e-62, bitscore:
                     199.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             11156..11911
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_10"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4.1e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(12050..12997)
                     /locus_tag="ctg466_11"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACGGKKQCAQCP
                     KAVDNAIIYASHPRGFHLPARKCEENIVIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(13062..14030)
                     /locus_tag="ctg466_12"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATAMASVATFDAMKEFMTDVKVTYSAPDWSLTGGTYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAAGAIYPSITYTVADVAAQTDLVAAKVTDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSTWKSQEGTATYA
                     HTIDGGALEVTTTGVEVNAAWMLMPQTLDANAKINVVYDIEKDGTLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             complement(14076..15080)
                     /locus_tag="ctg466_13"
                     /transl_table=11
                     /translation="VASNVGEMSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSG
                     VQIKLDWKGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNT
                     ESIQIRGDESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLNWK
                     PEAVVDHYSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLL
                     WGYFSSFVLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPD
                     VGVPGSEIHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(15056..15679)
                     /locus_tag="ctg466_14"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLRNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKVSLVWLLTSGR"
     CDS             16116..16328
                     /locus_tag="ctg466_15"
                     /transl_table=11
                     /translation="MKKSALILLSIILLIAGCSRQPAPAAKIPITSAHRGAATIAPENT
                     MASVDSCIKYGVGNIECDVCISKDSV"
ORIGIN
        1 ggataatgca gtagataact aactaaatcg taacctatta ctatcaagag caattaacct
       61 acgctcattt ccaataaatt acactctttt cgtaacttca gtatggcaaa catgaaagtt
      121 ctgtatccgg tttgcattat ctttgtactc aaaattgaca tacctatgga tatattgttt
      181 cttgtcggag gactgctcct cattcttctg ggtgccaatg gcttgacaga cggtgccgca
      241 tccgttgcca aacgtttcca cataccgtcc atcgtcatcg ggctcaccat tgttgccttc
      301 ggcacttccg caccggaact caccgtcagc atatcctctg ccctaaaagg cagtgcagac
      361 attgccattg gcaatgtggt gggaagcaat acgttcaata ccctgatgat tgtgggttgt
      421 acggcccttt ttgccccgat agccattacc cgtaacacac tgaaacgcga aatacccctt
      481 tgcatccttt catccttcgc cctgctgatt tgtgccaacg acgtcttact ggacagcagt
      541 ggggagaaca tactcagcat caccgacggc ctattgctgc tatgcttctt taccattttt
      601 ctgagttata cttttgccat tgcaaaaagg gatggaagta tgaaggaacc ggaaaaggag
      661 tacttacagg aagaagacga aatcaggctg ttacccgcgt ggaagtccgc cctatacatt
      721 ctcggcggac ttgccggcct catcatcgga ggtaatttct ttgtagacgg tgccagcggc
      781 atagcccgcg gattgggtgt cagcgaatcc atcatcgggc tgacgctcgt agcaggcggc
      841 acttcactgc ccgaactcgc cacctccatc gtagccgcct tgaagaaaaa ccccgaaata
      901 gccatcggaa acgtcatcgg aagtaatctc ttcaatatat tcttcgtact gggttgttcg
      961 gcctccatca ctccactgcg tctgacgggc atcaccaatt tcgatttgtg ggtactcgta
     1021 gggtccagca tcctgctttg gctgttcggt atctttttcg ggaaacgcat catcacccgg
     1081 gtggaaggaa gcattctgat tctctgctac attgcctaca cagcggtact gatatacaac
     1141 ctctaacagc aaatttacaa acaccctacg cggtatttta aagattatca cgtattttta
     1201 aataaggcaa gctgtacctc ggcataaaaa ataagcaagc ttattttgtt ctgctctcag
     1261 tttgcattac ctttgtggtc tcaatattga acaactatgg caattacaat caagaaagta
     1321 accacaagac gggaactgga gcgctttatc cgtttcaact acctgctata caaaaacaac
     1381 ccttattccg tccccgacct tttcgatgac atgctcaaca ccttcaacaa gaagaaaaac
     1441 gctgcattcg aattttgtga agccgactat ttcctggctt atcgggaagg taaaatcgta
     1501 ggacgtgtag ctgccatcat caaccacaag gcaaaccaaa cctggaacaa aaaggaagtc
     1561 cgcttcggct ggatagactt catcgatgat gcggaagtct ccgatgccct gattcgcacc
     1621 gtggaagaat ggggaaaaga acggggaatg acacatatac aaggcccgct gggattcaca
     1681 gatttcgatg ccgaaggtat gctcatcgaa ggattcgacc agctcagcac catggccacc
     1741 atttataact atccctacta tccgcaacat ctggaacgca tgggctttga gaaggatgcc
     1801 gattgggtgg agtacaaaat ctacattccc gacgccatac ccgacaagca caagcgcatc
     1861 tccgacctca tccagcgcaa gtataacctc aaggtaaaga aatacacatc tgccaagaag
     1921 attgcccaag actacggtca ggccatcttc gaactgatga acgaagccta tcagccactc
     1981 tatggctatt ctgcactgag ccaacggcag attgaccaat acgtcaagat gtacctgccc
     2041 atcctcgacc tacgcatggt gacattgatt accgatgccg atgaccagct gcttgccgta
     2101 ggcatttcca tgccgtcact tgccgaagcg ttgcaaaaag cccacgggcg cctgcttcct
     2161 atgggttggt atcacctggc caagaccatc ttcttgaaga aatatcccaa gatgctcgat
     2221 ttgctgctgg ttgccgtgaa accggagtat cagaacaagg gggtaaatgc attgttgttc
     2281 tccgacctta tccccgtcta tcagcaactt ggtttcgagt atgccgagag taatccggag
     2341 ctggagctga acggcaaggt gcaagcgcag tgggagtact tcaagacgga acagcataaa
     2401 cggagaagat gctttgtgaa aggaataaaa taagttctaa atccagaata taagcttgtc
     2461 agaagtccat aaaagacatt atttttttgc gaacccccga atttctcatt acctttgtcg
     2521 caatgcgcaa tatgaaggaa taacgtactt atggaagata acaacaatat gaccctgccg
     2581 ctggaagaag cagacaacaa tatcacagag agccccgttt ccagcgtgga atataccgac
     2641 gacaacatcc gccacctgga cgacatggag catatccgtg tccgttccgg tatgtacata
     2701 ggccgtctgg gcgacggctc acagaacgat gacggcatct atgtgttgct gaaagaagtg
     2761 atggacaaca gcatcgacga gttcaagatg ggtgccggaa agcgtataga agtgactata
     2821 gaagacagtc tgcgtgtcag cgtacgcgac tatggacgag gcattccgca aggcaaactg
     2881 gtagaggcgg tcagcaaact gaataccggg ggtaaatatg actcgaaggc tttcaagaaa
     2941 agtgtcggac tgaacggcgt gggcatcaag gcggtcaatg cgctgagtag ccgtttcgag
     3001 gtacgcagtt accgcgacgg caaagtacgt accgccatct tcgagaaagg aacgctgttg
     3061 agtgatgtga ccgaagactc gacagaagaa agcggaacct atatcttctt cgaaccggac
     3121 gccacactct tcctgaacta ttccttccag aaccagttcg tagaaaccct gctgcgcaac
     3181 tacacctacc tgaatacggg cctcaccttc atttacaacg gccagcgcat cgtttcccgc
     3241 cacgggctgg aggacttgct gaaagacaac atgaccagcg aaggccttta cgacatcatc
     3301 cacctgaaag gagaggacat cgagattgcc ttcacacaca ccaaccaata cggcgaagag
     3361 tactactcct ttgtcaacgg gcaacacacc acccaaggcg gcacacacca gactgccttg
     3421 aaggaacaca ttgcccgtac catcaaggag ttctacaaca agaaccagga atatgccgac
     3481 atccgcaacg gactggtagc cgccattgcc atcgacgtgg aggaacccat gttcgagagc
     3541 cagaccaaaa cgaaactggg cagcaacaac atgtggcctg ccgcgccgca ggaacacaag
     3601 cccgccggcc ccacggtgaa caaatacgta ggagacttca tcaagacgga agtggacaac
     3661 tacctccaca agaacccgct tgtggccgaa gtgatgctgc aaaagataca agactccgag
     3721 aaagagcgca aagccattgc cggcgtcacc aagctggcac gcgaacgcgc caagaaagcc
     3781 aacctgcaca accgcaagct gcgcgactgc cgctaccact tgagtgacgg taaaggcaaa
     3841 gaccaggaaa ccgaatcctg catcttcatt accgagggag actccgccag cggttccatc
     3901 accaagagcc gcgacgtgaa tacccaagca gtattcagcc tgcgtggtaa accgctaaat
     3961 tcctacggac tcaccaagaa agtagtttat gaaaacgaag aattcaactt gcttcaagca
     4021 gccttgaata tagaagacgg catagagaca ctgcgctaca acaaagtcat cgtagctacc
     4081 gatgccgatg tggacggcat gcacatccgc ctgctcatca tcaccttctt cctgcagttc
     4141 ttccccgacc tgataaagaa agggcatgta tatatcctgc aaacccctct cttccgcgtg
     4201 cgcaacaaaa agaagacaag ttattgctat acagaggagg aacgtgtgaa agccattgaa
     4261 gaactgggtc ccaaccccga aatcacccga ttcaaaggtc tgggagaaat ctcgcccgac
     4321 gagttcaagc attttatcgg caaggatatg cgtctggaac aagtgtccct gcgcaagaca
     4381 gacctcgtaa aagagctgct ggaattctac atgggtaaga ataccatgga acgacaaaac
     4441 tttattatca acaacttggt tatagaagaa gatttggcat catgagaaga gctatctttc
     4501 cgggaacatt cgacccgttt actatcggac actcttcggt agtgagccgt gcactgactt
     4561 ttatagacga aatcgtcata ggcatcggca tcaatgaaaa taagaatacg tatttcccct
     4621 tggaaaagcg cgaacaaatg atacgagact actaccggaa cgagccgcgc atcattgtgc
     4681 agtcctatga ctgcctgact atcgactttg cccggcaggt agatgccagt ctgataatac
     4741 gcggcatacg caccgtgaag gatttcgaat acgaggaaac cattgccgac atcaaccgca
     4801 aactgaccgg catagaaacc atcctgctct tcaccgagcc ggaacttacc tgcgtcagtt
     4861 ccaccaccgt gcgcgaactg ctgcaatacg gcaaggacat aagcatgttc ataccggagg
     4921 gaatggagat tagggattaa ggataaagga ttagggatta aaatggaaat gatgaaaaaa
     4981 ctatttacta ttataatatg tatatgcgcg gtgacggcgc aagcgcaaaa gccgaacaat
     5041 gaagccctgc gcaaactgca aatggcagag tttgccatca ccaaccttta tgtggacaag
     5101 gtggatgaag acaagctggt ggaagaagcc atcatcaaga tgctggcaca actcgacccg
     5161 cactccacct acaacaacgc cgaagaagtg aagaagatga acgagccgtt gcaaggcaat
     5221 ttcgagggca tcggcgtaca gtttcagatg atagaagata ccctgcttgt gatacaaccc
     5281 gtgagcaacg gaccttccga gaaggtgggc atccttgccg gcgaccgtat cgtagccgtc
     5341 aatgacagcg ccattgccgg agtaaaaatg agcacggaag atattatgag ccgcctgcgc
     5401 ggaccgaaag actcggaagt gaaactcacc atcgtgcgcc gtggcgtgga cgaccagctg
     5461 tacttcaccg tgaagcgtga caaaattccc atcctcagcc tggacgcatc ttacatgata
     5521 caacccaaaa ccggctatat ccgtatcaac cgcttcgggg caaccaccgc cgaagagttt
     5581 gcagaagccc tgaaaagcct gcaaaagaaa ggaatgaaag acctcatcct cgacctgcaa
     5641 ggaaatggag gagggtatct gaatgccgcc atcgaccttg ccaacgaatt tctgaagcaa
     5701 aaagaactca tcgtctacac cgaaggaaga gccgcacgcc gcagtgattt ctttgccaaa
     5761 ggtacgggca acttcaagaa cggccgtctc atcatattgg tggacgagta ctccgcttct
     5821 gccagtgaaa tcgtgaccgg agccatccag gactgggaca gaggcgtggt agtaggacgc
     5881 cgcaccttcg gcaagggatt agtacagcgt cctatcgacc tgccggacgg ttccatgatt
     5941 cgcctcacta tcgcccgcta ctatactcct tcgggccgtt gtatccagaa gccttacgac
     6001 agcaccgcca acctcgacgg ccgcctaacc ggcgagaaca gtcaggataa gtataaccag
     6061 gaactgatag accgcttcaa tcatggagaa atgattcatg cggacagtat ccattttgcc
     6121 gactccctga aagcacagac caagcgtatg ggacgtaccg tttacggagg tggaggtatc
     6181 atgcccgact tcttcgtccc catcgacact acccagtaca cagactatca ccgcaacctc
     6241 gtagccaaag gcgtggttat caaagccact accggctaca tcgagaagca ccggaaggag
     6301 ttgcagaaca aatacaagaa attcgaagcc ttcaacgaga agttcgagat agacgataac
     6361 ttccttgccg aaatacgtac gcttgccgac aaagagaaaa tcaagtttga cgagaaacag
     6421 tacaaccaat ccctaccgct catcaagaca caacttaaag ccttgatagc ccgtgaccta
     6481 tgggacatga acgaatactt ccaggtgatg aacagcacga accagagcgt gcagcaagct
     6541 ctaaaagtgc tgaacgaagg catctacagc actattatcc aatagccgac ttgaaacaaa
     6601 cttaggcgcg gattatgcgg atttagttta tctaactccg cgtattccgc gtaattcgcg
     6661 cctaaaatca ttctccgaac agccacttat tcagccactt gttgacgtag atgttgacca
     6721 cagcacatcc agcaccgatt gcagcccccg ccaacacatc tgacggataa tgcactccct
     6781 cgttcatacg ggaaactccc acggaacaag cccacagggc agacggagct atcacatacc
     6841 atttaggata ctttacactg agcgaggtgg caagggcaaa agccgtcgcc gtatgtccgg
     6901 aaggaaaaga cgggctgcct tcatggctat atgcatgcac tctgtcggga tatttatcat
     6961 aaggacgctc acggtccacc agatatttca ttccataagt cacaacaaaa gcccccgcta
     7021 cacttgtacc tacgtagacc gcatctttca gcaaaccctt atcatgtttt atccaagcgg
     7081 caaccgccat cgccaccgga acaccgacag caacataggg ctccgaacgt gaaattatct
     7141 tattatagtt acggacaaac ttgccatccc aactgttaac ccggtgcaaa gtgttaatat
     7201 cccaattctg tgccgaaaga ccggatacaa caaggtagat aaaatataca aaaaaaatag
     7261 cctttttcat aagtccttta tattagtttg acgcaaagat aggacaaata gatagagttt
     7321 tcacaaaaaa attctatctt tgttgccaca tttataataa ttcgctaatc atttcatgag
     7381 actggaaact tgctgcaacc gacagattga ttgtatggta tgtccccaaa aatcagaagg
     7441 agtattggtt taccgccact accccaaggg acaacatttc tctgctgaaa agtgcacaca
     7501 gaacagcatg atatttatgc tgaaaggtga attacttgta aacagtgacg aatatccggg
     7561 caccactctc caaagccgcc agctcatctt gcaagccatc ggctccaaag tagaactcct
     7621 ggctttgacc gaagtggaat atattgtgta ttggttcacc gagcttcctc tgatttgcga
     7681 agagcgctac aaggagatac tgaaacgctc ggaagccccc ttgacttata ccccgcttac
     7741 cgcgatttcc atgctcgaag ggctcctgaa aagccttgcc tgctacctca acgagcaacc
     7801 ctatgcgtgc agcaaataca ttgaaatgaa atgccaggaa ttggtataca tattgacatg
     7861 ctactatccg ctacaccaaa tcagtacatt cttctatccc atcagcactt atacggaaag
     7921 cttccaatat ttcgtcatgc agaactacga caaggtgaag aatgtggaag agtttgccca
     7981 cctcggtgga tataccacca ccacattccg ccgtctgttt aaaaatatgt atggggtccc
     8041 ggtctatgaa tggattctgg acaagaaacg tgaaggaatt ctgaacgacc tgcaatacac
     8101 caaacaacgc atttcagtca tcagcgcccg ctatggcttt gattccctat cccactttgc
     8161 ccacttctgc aaagactctt tcggagacac gccccgcgcc ctgagaaaac gttcagcaaa
     8221 cggagaaaag atttccatta tctgcaaaga gcaaggcaaa gaccaggagg acgagtaaac
     8281 cttttacttg tccgtaaact tcgcattctg ccggattacg gaattatttc tttaatcgct
     8341 tgctttatcg ctggatttct cctatttttg cgaaacattt acagaagtat cctgatagaa
     8401 caaattttca aactattaaa taacttaaat tcaatcattt atgtggttaa gtaattcatc
     8461 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctgacatt
     8521 tcacatggcg atgaacctgg ttgcattagt ctcggctaat ggctacaaca tggtttgtga
     8581 gttcctggga gcaaactggt acgcattggt ggctacggta ggtctggctg ccttattcat
     8641 catccacatc atctacgctt tctggctgac tatgcagaac cgtaaggcac gtggtagcga
     8701 acgctatgcc gttacggaaa agcccaagac tgtggaatgg gcttctcaaa acatgctcgt
     8761 actgggtatc atcgtaatcg tgggtttggg cctgcacctg gtaaacttct gggctaaaat
     8821 gcagcttccc gagttgatgc acaacatggg catgcatgct gacaccctca cgctggcata
     8881 tgcagccaac ggtgtctatc acattcaaaa caccttcagc aatccggtat tcgtagtgct
     8941 ttacctcgtt tggctgagcg cattgtggtt ccacctcact cacggtttct ggagctccat
     9001 gcagtctttg ggctggaaca acaaagtatg gattaaccgt tggaaatgta tctccaacat
     9061 ctattctact atcgttgtcc tctgcttcgc tctggtagtt gtcgtattct ttgcaaaatc
     9121 attgtgcggc gcttgctaaa ttcaaattgt aaatgactaa attgtaaatt gcattatgac
     9181 taagatagat tctaaaatac cggaaggacc ggtggctgag aaatggacca attataaggc
     9241 tcaccaaaaa ttagtaaacc ctgccaacaa acgtcgtctg gacatcatcg tagtaggaac
     9301 cggacttgcc ggtgccagtg ctgccgcctc tctgggcgaa atgggtttca gagtattcaa
     9361 cttctgcatc caggactctc cgcgccgtgc acactccatc gctgcacaag gtggtatcaa
     9421 tgctgctaag aattaccaaa acgacggtga ctctgtatac cgtctgttct acgatacagt
     9481 aaagggtggc gactaccgtg cccgcgaagc caacgtttac cgtctggctg aagtatccaa
     9541 caatattatc gaccaatgcg ttgcacaagg tgttcctttc gcccgcgaat acggcggtac
     9601 actggacaac cgttctttcg gtggtgctca ggtatcccgt actttctatg ccaagggtca
     9661 gaccggacag cagctgttgc tgggtgcata ctctgcattg agccgccagg tgaacgtagg
     9721 cactgtgaaa ctgtataccc gctacgaaat ggaagacgtt gtcctcattg acggacgtgc
     9781 ccgcggtatc attgcaaaga acctcgttac cggtaaattg gaacgttttg ccgcccacgc
     9841 tgtggtaatc gctaccggtg gttacggcaa tgcctacttc ctttctacca atgcaatggc
     9901 atgtaactgc tctgcagcaa tggcttgcta ccgtaaaggt gcctggtttg ccaaccctgc
     9961 ttacgtacag attcacccca cttgtatccc ggttcacggt gacaagcagt ctaagctgac
    10021 tttgatgtcc gaatctctgc gtaacgatgg tcgtatctgg gttccgaaga agctggaaga
    10081 tgccaagaaa ctgcaggaag gtacactgca aggaaaagat attcccgagg aagaccgcga
    10141 ctactacctg gaacgccgtt atccggcatt cggtaacctc gttccgcgtg acgttgccag
    10201 ccgcgctgcc aaagaacgct gcgacaaggg cttcggcgtg aacaacaccg gtcttgccgt
    10261 attccttgac ttctccgaag ctatcaaccg tctgggtaaa gatgtcgttg cacaacgtta
    10321 cggcaacctc ttcgatatgt atgaagaaat cactgatgtc agcccatacg aaaacccgat
    10381 gatgatttat ccggctatcc actataccat gggtggtatc tgggttgact acgaactgat
    10441 gacctccatc aagggactgt tcgccatcgg tgaatgtaac ttctccgacc acggtgcaaa
    10501 ccgcctcggt gcttccgccc tgatgcaagg tctggccgat ggttacttcg tattgcctta
    10561 cactatccag aactatctgg ccgaccagat tacagttccc cgtttctcta ccgacctgcc
    10621 cgaatttgca gctgcagaaa aggccgttca ggagaagatt gactggatga tgaacatcaa
    10681 gggtaagaag tctgtagact ctatccacaa ggaactgggc cacattatgt gggaatatgt
    10741 aggtatggga cgtacggccg aaggcttgaa ggaaggtctg aagaagctga aagaagtccg
    10801 caaggagttc gagaaagaac tgttcatccc gggcgacaag gaaggtatga atgtagaact
    10861 cgacaaggct atccgtctgt acgacttcat cactatgggc gagctggttg cttacgatgc
    10921 actgaaccgt aacgaaagct gcggcggtca cttccgtgaa gaatatcaga ctgaagaagg
    10981 cgaagccaag cgtgacgatg aaaactactt ctacgtggct tgctgggaat atcagggttc
    11041 tgacgaaaag gaaccggtat tgctgaaaga gccgctggtt tacgaagcaa tcaaggtaca
    11101 gactcgtaac tacaagagct aatcgggaag ttgaacattt aaagaattaa agaaaatgga
    11161 taaaaatata tcatttacgc tcaaggtatg gcgccagaag ggtccgaaag caaaaggcgc
    11221 ttttgaaaca taccaaatga aagatatccc gggcgatact tcattcctcg aaatgctgga
    11281 tatcttgaac gaacagctga tttctgaagg taaagaaccg gttgtattcg accacgactg
    11341 ccgcgaaggt atctgcggta tgtgttcgct ctacatcaac ggacatcccc acggtcctgc
    11401 aaccggcgct acgacttgcc agatttatat gcgtcgtttc aacgacggcg ataccatcac
    11461 tgttgaaccg tggcgctctg ccggtttccc ggttatcaag gacttgatgg tcgaccgtac
    11521 ggcctacgac aagattatgc aggcaggcgg ctacgtcagc gtacgtaccg gtgctcccca
    11581 ggatgccaac gctatcctga ttccgaagcc catcgctgac gaggctatgg atgctgccag
    11641 ctgtatcggt tgtggtgctt gtgtggctgc ttgtaagaat ggttctgcta tgctgttcgt
    11701 ttctgccaag gtgagccagc tgaacctgtt gccccaaggc aaaccggaag cattgcgccg
    11761 tgccaaggct atgttgagca agatggacga actcggtttc ggtaactgta caaacactcg
    11821 tgcgtgcgaa gctgaatgcc cgaagaatgt ttccatcagc aacattgctc gcctgaaccg
    11881 cgactttatc attgcgaaac tgaaagacta atccggtctt tctgcaaata atataggatg
    11941 cgcttcggat aaaccttttg agcaagctca gatttatcac tcagctttca ctatatttga
    12001 ttaatatcac aagagactcc tctgccggga aaccgccgga ggagtttttt tatgacatgc
    12061 cgtttacttc agataaattg ccggcacgca agctacgggg agaagccccg aaattctttt
    12121 tgcagaaatt ggaaaaatga ggcagcgatt caaagccata tttatagcaa atctctgata
    12181 tggaagcatc cgtatagcga agttcataaa ccacgctttc cttcctccgt tccatcatcc
    12241 actcgtacac cggttgatga aaaacagaat tgaatatacg ccggaaagta gccactgtat
    12301 atcctcccaa ctgggcaagt tcctctaccg tcttgacttt ggcatgattc tgcaagacaa
    12361 agtagtggaa ggaattagta tactgggcaa gaggatgtat cagcatggaa agctcatagt
    12421 cggagtagta atttccaaga atgaaagcaa gttctttccg tttgaaacaa agcatttccc
    12481 ggcaaatttt ctcctcggat aaataggcct tggaactttc cagaaagagc tgcaactcgg
    12541 gagtaatggt caaaggatag aatatcaatg gaggggtaac ctctttcata atatggttat
    12601 accggtcctc acagaagaat tcaggcttac tgaaccggta acaaacacat tccacatccg
    12661 tcatggcaag tatttcgtac tttgaaccaa tggcttgaag gatgaactca cctgcatgca
    12721 acacagttcc cgcatactcc ttactgttga caagcacttc ccctttcagc aggaaaatta
    12781 caatattttc ctcacacttt cgcgccggca gatggaatcc tctggggtgg gaagcatata
    12841 ttattgcatt gtccacagcc ttgggacatt gagcgcattg ttttttacct ccgcaagcag
    12901 aagagttggg catcggcaag tagatttgtt tgtttgttgc agtgacaaaa atagataaat
    12961 aatactcata aaagaaacat tccccgaaaa ctttcataaa gaagtttcgg ggaatgaata
    13021 aaatagaagt aattcagttt tttattgcgg acagtgccgt tttatttttc cacgttcgta
    13081 tcatcagccg tactccatgg accaacttca ggtacaaagg ttactttcgc cgccttattg
    13141 gccagcgtca gcgtataacg tatctttttg ccttcacccc aggcttgtgt atcattcaag
    13201 tcaatggcgg aagttacagt atcaagaaga gtaccatcct tctctatgtc atagacaaca
    13261 ttgattttgg cattcgcgtc caacgtctgg ggcatcaaca tccaggctgc attcacttcc
    13321 acacctgttg tagtcacttc caatgcacca ccgtcaatcg tatgtgcata agtggctgtt
    13381 ccttcctgtg acttccatgt tgaatcatca aaaccataag ttcctttatt gtgcacgccg
    13441 gatattgtaa gtgttttcag tttataagtc aaagcgtcgg ctgccttgac agtgaaattt
    13501 atttgggtca gtatatggcc gaatttcaaa gataccccac tggcatttga tgccttggtt
    13561 gcatccgtca ctttcgcggc taccaagtcc gtttgggcag ctacatctgc taccgtataa
    13621 gtaatggaag gatatatagc accagcagcc ggttgattgt acgtcaaggc cccggtaccc
    13681 ggattcccgt aagcaaagaa ctgcaagtta tccgtcattg gccaataata tgttccccca
    13741 gtcaaactcc agtcgggagc actataggtt actttaacat ctgtcatgaa ttccttcatc
    13801 gcatcaaaag tcgcaacgga ggccattgct gtcgctcccg tattataagc atacacagtg
    13861 aaccctacct tctgcaattc cggcaaatca gtcactgtgg ctctcgtagt gttacccact
    13921 actgttccca atttaatctc cgccttttgt ccggcattct ctatctcctc actttccgag
    13981 caactcatta ctgctgctgc agccaaagcc aaaaataaaa ccttcttcat aattgtctgt
    14041 tattaaagtt aatatattta tttgtctgtt tgctatcaat tcaccggtag ctccacatcc
    14101 gtctcatcat cccaatcatc cacatcgcca ccaatccctc catctccttc atcggttccc
    14161 ggttccaaat catccaccac aaccttgtcc tccggtacgg gaacctcgat atggatttcc
    14221 gacccaggaa cgcccacatc aggttcttct tcgcctcctc ccgagggagg agctgtttca
    14281 atcacttccg tgatatccac cttcacctct tgaaccgttt tatctcgttt cacaatcttc
    14341 agtgtcagca acataggact atccgcacgg gtcttggtat ctttcagtaa tacaaaactg
    14401 gagaaatacc cccataaaag cccgttttca cgctttgtat ccacacatat aggtacctcg
    14461 ctcaaatggc aagcacggtt gcctataaag taacttccgt tcaagccgtc cacatggcag
    14521 atgatgctcg atattctatc ccatccttcc acctttatat caaaggaata atggtccact
    14581 accgcttccg gcttccagtt caacggaagc gccacatcac tctgccttat ttccacctcg
    14641 tccaaagcca ccacatacaa agggtcgggc gaccaaacca tatcttcgtg tacatccagc
    14701 cccgtacagt gtcccgtaaa agcctcaatc gtctcataac tctcgtcgcc ccgtatctgt
    14761 atactctccg tattgaagtt ataggccacc accgcatact tccccggcgg taccttcacc
    14821 tcaccccctc cggcaggcag ataactttca acctttctcc cctgagtatc tttcggatag
    14881 aagataatcc gcatggtctg cggcagctta tccgtcaccc ctttccaatc cagtttaatc
    14941 tgtactccgc taacgggata atcatccagc atatcgcgga agtcacagct tcccagcatt
    15001 ggcaacagcc cgaagaacag ccagagaatc atatgccgtg catctttcat accactcatc
    15061 tccccgacgt tagaagccac accaaagaaa cttttgcttt tgtcggcccg ataaagtgat
    15121 actttccact gctgacccaa accaagtcat ttccataaga agtatatttc cggtactccg
    15181 tatccaagta tccaataccc acactgaatt caatcgccag atgccgagcc agtggacgca
    15241 cgtatccata agttattcct gcagctgcgt aatacttccc ccggtatccc ttctcctttt
    15301 tcaactgaaa atcataggta cctccttcgg catatgctcc cagaaagtgt ccggacaatc
    15361 ttccgcgcgt atggcggttt ctcaaccagt aacgcgcctc tgtccctccc gaaaggagct
    15421 gatagcagaa attacatccg ctgtcagacc accaagggca tttgtactca acattcaaag
    15481 accacctctt tcccaatggc agctccactt ctatgttcgg agccaaggcc aggtcgtaaa
    15541 gcaaattatt ttttaacgcc agcaccgttt tacaagtatg gctatgggat tctaccgact
    15601 tattctgccc tattacctgc cccgacatca tgcaaaaaag gagtagccaa aagacatata
    15661 taaaaatgcg ttttcccata atttcgcgtt gtatacaaac aaaagtagaa gataattacc
    15721 gaataaaaat cactttccat cactcttttc aaaggctgaa aggttctgtg aaacgattga
    15781 aacagatttg caacttctgc cttcttcggg accctatgaa taggttcttt ccatactctc
    15841 tcagaaagtc aatccgtgtg cgaaaacagt aaaattcagt gaaagaaata caaaagaagt
    15901 agcaggagca ttctgaaatt tggaagataa caacgggaac cttacatttg caatgtgatt
    15961 tttttcatag tattagattt aaggttaaca aaggttggag tacagcggta ctcctttttt
    16021 ttatgcccat acgtttctcc gaatgacaaa aaatagctat cttcgatgac ttttataacc
    16081 attaaagata aatatatcac catcccacac tcattatgaa aaaatcggca ctcatattac
    16141 tctccataat cctgcttatt gctggatgtt ctcggcaacc tgcccctgcc gccaaaattc
    16201 ccattaccag cgcacaccgt ggtgcagcta ccatcgctcc cgaaaacaca atggcatccg
    16261 tagattcgtg catcaaatac ggtgtaggca atatagaatg cgatgtctgc atcagtaagg
    16321 acagtgtc
//
