LOCUS       gnlProkkaBCNCMMLM_68   12337 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BCNCMMLM_68.
ACCESSION   gnlProkkaBCNCMMLM_68
VERSION     gnlProkkaBCNCMMLM_68
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:29:20
            Original ID  :: gnl|Prokka|BCNCMMLM_68
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12337
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12337
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1983:2337]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1984..2337
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12337
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12337
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             287..418
                     /locus_tag="ctg68_1"
                     /transl_table=11
                     /translation="MEQAQQEEQTNPYNLPVGTTAPKTDAAAPVEAPATETPATPAN"
     CDS             697..1977
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 87; E-value: 1.7e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg68_2"
                     /transl_table=11
                     /translation="MSPLKPMLEKELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDK
                     MGVRFTGMGACILMVLGCGLKYYAISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIA
                     GITVSKIIVKWFKGKEMALAMGLEMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNI
                     PMPILLCLIMLCIGTIAFFIYTFYDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWL
                     IALLCVLFYSAVFPFIKYATDLMVQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRI
                     GKGATLMIIGAVMLIGVHTLFALPILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIP
                     EKQLGTAYALIFWVQNWGLMGVPLLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGV
                     LALIVALMLKAEDKKKGYGLQEANIKK"
     CDS             1984..2337
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_3"
                     /sec_met_domain="PF05402 (E-value: 4e-17, bitscore: 53.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 6.2e-10, bitscore:
                     29.7, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSTDIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(2471..3526)
                     /locus_tag="ctg68_4"
                     /transl_table=11
                     /translation="MKKLIILTGLLLSTSAYAQTEVTAGVTRGKDYGVTYALPKTAINI
                     EVKVNKVTYTPGEFSKYADRYLRLTDVSGEPQEYWELVSVKAKSVGIPDSEHTYFVKLK
                     DKTVAPLIELTEDGIVKSINVPLSPKKSAPMQPATTQKKKINPRDFLTEEILMAGSTAK
                     MAELVAKEIYNIRESKNALVRGQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKD
                     EKIFNIRLTPDKEMDNEVAFRFSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKK
                     VDGIAYNVPGKAQVTLTEGKKQWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTG
                     GLIKVDREEGE"
     CDS             complement(3599..4738)
                     /locus_tag="ctg68_5"
                     /transl_table=11
                     /translation="MDGLFGSGLNKPLSGGFAAVVKYINASPATVVAIDIPSGLMGEEN
                     TFNVKANIIRAQLTLSLQLPKLAFLFAENSEFVGEWKLLDINLSREAIEETESNYALLE
                     AEEIHTLIKPRNTFSHKGNFGHALLIAGSYGMAGASILAARACMRSGVGLLTVHAPIRN
                     NAILQISVPEAIIESDASDTYFACPTDTDDYQAVGIGPGIGRSEETEAALLEQLSGCQT
                     PLVLDADALNILANHRHALTTLPKGSILTPHPKELERMVGKCQNSYERLMKACELARTA
                     KVHIILKGAYSAIITPSGKCYFNSTGNPGMATAGSGDVLTGVVLALLAQGYPAEEAAKI
                     GTYVHGLAGDFARKKQGVISMTAGDIISNLPLAWRLVSE"
     CDS             4745..5128
                     /locus_tag="ctg68_6"
                     /transl_table=11
                     /translation="MIHRQGRRYKLCAYFAELHIIHHLYQLLVGLAVGRQFPFRVKQIG
                     FDLVFLFRQHSGHGKGISAIVARSGKYRDGSCDVPAFGDGFGQCLCGPLHQVDRCNRFM
                     FYGVSIQFLDAATWKNLHGELSF"
     CDS             complement(5154..5417)
                     /locus_tag="ctg68_7"
                     /transl_table=11
                     /translation="MGFFIAMNDFLGYTGTVIVLAVKEFFSPDINWTAFYNLMAGYVGI
                     ICFVAFVCSFIYLHQRYRRENYGKTGVFRKKEEEKEVPDFVY"
     CDS             complement(5419..5700)
                     /locus_tag="ctg68_8"
                     /transl_table=11
                     /translation="MDVCTGRQRSNPHYSDNFRINGVRQKQLESTVDITGIDHCQHGSD
                     GSRFVWLRTIAAERHRLAIHPEPVSLSGFSHFPDYLLRPFYRLLQNSR"
     CDS             5866..6159
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="MAMSSAVGCGSRLRAYPNKASRGRATPPIRAGIQNSLMFKVSMTY
                     KPADLAVPELMTILTPSKLARMSVIRLPSIKLKMIPHIHPSESPFRNMAPIL"
     CDS             6929..7432
                     /NRPS_PKS="Domain: oMT (8-107). E-value: 3.1e-13. Score:
                     40.4. Matches aSDomain: nrpspksdomains_ctg68_10_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 92.7; E-value:
                     4.3e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_10"
                     /transl_table=11
                     /translation="MQWQPEWSVLDIGCGGANLLQILQRCPQGKAYGIDISPESVTFAR
                     KKNKKYLGTRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGS
                     FLICCEISDPANKAWTGLVEGMEIHSCDELKAILSKSGFTDTVIFRTKKEELCLVSHRQ
                     TVRL"
     aSDomain        6953..7249
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg68_10_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.10E-13"
                     /label="ctg68_10_oMT.1"
                     /locus_tag="ctg68_10"
                     /protein_end="107"
                     /protein_start="8"
                     /score="40.4"
                     /tool="antismash"
                     /translation="VLDIGCGGANLLQILQRCPQGKAYGIDISPESVTFARKKNKKYLG
                     TRCFIEQGGVHRLPYPDYAFDAVTAFETVYFWGNLQHAFTEVARVLKPGGSFLI"
     CDS             7580..7765
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MLTSYSSLIKILLFDNQLLIFWMRSAVKFFSYVQDVRSCLFIKLP
                     LRLSIACLSTYFHILL"
     CDS             8116..8664
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MLKLFLTNVVLETTDSDKHWYVVLTRTNSERKVRDYFQLQEVDTF
                     LPVQNRVIEREGKRIERERLLLPRMVFVHISRQEMAAVRSTLNVYDFLRDRSTGAPTCI
                     PDAQMADFRYMLDYSQDQVILTGESIPKGTRVVVAKGDLQGLRGELVRYNNKYHILVRI
                     DMFGSAMVTIPASYVRKEK"
     CDS             complement(8593..8835)
                     /locus_tag="ctg68_13"
                     /transl_table=11
                     /translation="MNYDSSILFGFYLYRRVIISNRIVSNDVTGHYIYCYHPLHILLSP
                     LHIMVFSLHIYFLFLFPDVASRNCNHSATEHIDTY"
     CDS             8847..9245
                     /locus_tag="ctg68_14"
                     /transl_table=11
                     /translation="MKNSLCNSVSSVVKKLLEYGEDGTPVYVNELTALNQELRNLCADL
                     LLQKGESPEEEAEILVTLFKGYDTMLFNFSSENEQVIQELLDRSMTVLEKLPASVLKCQ
                     LLLECFEQTGDEELITSLGTVLDVMSIM"
     CDS             9374..10891
                     /locus_tag="ctg68_15"
                     /transl_table=11
                     /translation="MNKGGKHIAKNTVILYLRMMVTMLVTLYTSRIILESLGIEDYGIY
                     NVVGGVVTLFSFINGAMTSATQRYITFAIGKGDAIGLPKVFCISLLSHISIIAIVLFFS
                     ETIGLWFLNSYISIPNGKIVEANLVYQFSILAFCFQIIKVPYDANIIAQEKMSIYAYVS
                     IAEVIMKLCIAFLLQLFFSDRLVLYAFLIFFSSVLFFFLNKFFCLKMYPYCKYHFYWDK
                     DIYKELMSFSGWSFLGQVAIVFSSQGNNILLNMFYGVVVNAALGISNQVNSALMSFVSN
                     FQTAFKPQITKSYANNDFEYLFNMMFYTSKMSFYLIYLLAIPIIFNIDAILNCWLTVVP
                     TYTANFCILMIIYSLLDAVTGPFWMAIFATGKIKKYQIILSVFIFSSIILSYFSLYFGG
                     SPESVLWIRVGINVLVLLIRVYFVKYLLGVPLELFLHKVLLPVGYVVILSIPLSYLVYM
                     QIYNFHFIFILVVILLLNGVIVMFAGINKNERRQICNMVYNLKLKRV"
     CDS             10894..11367
                     /locus_tag="ctg68_16"
                     /transl_table=11
                     /translation="MESHDIGFYWDDFEVGKTFVHSLSKTIFESDNNLFCLLTMNYHPV
                     HTNVDYAAKNQHGRILVVGTLVFSLVVGMTVPDISGKAIANLCYEDIQHLGPVFIGDTI
                     YSKTIILEKYPSNSKKDRGIVYVKTIGYNQNGEEVISFKRKVLVKRREYESSI"
     CDS             11351..12235
                     /locus_tag="ctg68_17"
                     /transl_table=11
                     /translation="MSHLFRSLMFVPAHNERLLNSASRSDADVLILDIEDSVQPVSNKI
                     VARNNIVKYISGNIFFDRPIYPRINDRESGELLKDIYALTIPGVSGFMYPKSTKGEDIY
                     FIGKLLETVEYEKGFPIGTFKIIPLIETAGAIVNLKDICTACSRVVAVAFGCEDYVTDL
                     RGEHDEKGESIFMARSLISACARACNIYPIDTVHIKVHDLEDLEKNLILSKKLGFEGML
                     VLNPKELPLVHRYFSPTQEEVEWAKEMLALASDSVSEGKGVAVKGDKFIGPPMVKMANN
                     ILMKQQLIREKVQ"
ORIGIN
        1 gagaaattga ttattaacgc taaatcaaaa taacaaaatg tacttattat tagttatctt
       61 aatggttatt gcagccatac tgatgtgctt cattgtgttg attcagaact caaaaggcgg
      121 tggtcttgct tcagggttct catcatctaa ccagattatg ggtgtacgca aaactacaga
      181 ctttctggaa aaagcaactt ggggcttagc tgcatttatg gttgtgatga gcattgctac
      241 tgcgtatgtc gttccgactt cttcttctaa aacacaagat gtcattatgg aacaggcaca
      301 gcaggaagag cagaccaacc cttataacct gcccgtaggt actactgcac cgaagacaga
      361 cgctgctgct ccggttgaag cacctgccac agaaactccg gctactccgg caaactaaca
      421 acagattctt tttaagaaac gataagcgaa gctgcaattt caaaccgaaa cttgcagctt
      481 cgcttatttt ttgccgtaaa atgcatcttt ttgttaggca tacaaggcag atttagttac
      541 ctttgttcgc aataacactt ttactaattt ctgagtttaa atattacaat gacagaacaa
      601 ttgaaaaaca aattgagtga ctccaaaaca cttcgttgga gtgtgctcgc tctggtcgcg
      661 tttactatgc tttgcggcta tttcctcacc gatgtaatgt cccctttaaa gcctatgctc
      721 gagaaagagc ttctctggga tagtttggac tacggattct ttaccagtgc ttacggatgg
      781 ttcaatgtat tcctactcat gttgattttc ggtggtatta ttctcgataa gatgggagtt
      841 cgtttcaccg gtatgggagc ttgtatactg atggtgttgg gttgtggact aaaatattat
      901 gctatctcta ctacttttcc tgagggagct ttgattatgg gtttcaagac tcaggtcttt
      961 ctggcggctt taggatacgc tatctttggt gtcggcgtag agatcgccgg tatcactgtc
     1021 tctaagatta tcgtgaaatg gtttaaaggt aaagagatgg ctttggctat gggacttgag
     1081 atggcaaccg cacgtatcgg taccactttg gctatggtgc ttaccgttcc cattgccgat
     1141 tatttcggct atacggatga aagcggcagt ttccatacca atattccgat gcctattttg
     1201 ttgtgcctga tcatgctgtg catcggtact atcgcctttt tcatttatac cttttatgat
     1261 aagaaacttg acgcttcttt agatgctcaa ggagaagaac cggaagaacc gttccgtatg
     1321 aaggacgtta tgctgattgt caccaataaa ggcttctggc tgattgcttt attgtgtgta
     1381 ctattctatt ctgctgtttt cccctttatt aaatatgcaa ccgacttgat ggtgcagaag
     1441 tataacgtag accctaagct ggccggaaat attccgggat tactaccgat aggtaccatc
     1501 ttcctgactc cgttgtttgg tactctttat gaccgtatcg gtaagggagc gacgttgatg
     1561 attatcggtg ccgtcatgct gattggtgtg catactttgt ttgcgcttcc cattctgaac
     1621 gtatggtggt ttgccactgt gattatgatt gttctgggta ttgctttttc actggtgcct
     1681 tcggccatgt ggccttctgt tccgaaaatt attccggaga aacaactggg tactgcctat
     1741 gctttgattt tctgggtgca gaactgggga ttgatggggg tacctctgtt gatcggatgg
     1801 gtgttgaata cctattgcaa aggtcctgtt gtggatggag cgcagactta tgactatact
     1861 ttgcctatgg ctatctttgc ttgtttcggt gttttggctc tgattgtagc tttaatgttg
     1921 aaagcggaag acaagaagaa gggatacgga ctgcaggaag caaatatcaa aaaataacag
     1981 tatatggcag acgtgaaaga gaaaataaat cttttggatg taattccttt ccgtagtgaa
     2041 aatattacgg ccgaaaaggg aagcgatggt accgttacca ttgctttccc ccggtttaaa
     2101 tacgagtgga tgcggcgatt cttgttgcct aaaggaatgt ctacggatat tcatgtccgg
     2161 ctggaagatc atggcactgc cgtatgggag ttgattgacg gaaagagaac cgtacgccgg
     2221 attattgaag agctggcaga acacttcaat tatgaagaaa attacgaatc acgtattacg
     2281 gcttatatca ctcagttgca gaaagacgga tttgtgaaat tagtgattga gaactgattg
     2341 cattacgata tactatcgga atataataaa gagactccgg ctgatttaaa aatgaagtgc
     2401 accctaaaag ttaaacatga acttttgggg tgcacttcat ttaagatcgg ccggagtttt
     2461 tgattatgct ttattctcct tcttctctat ctaccttgat caagcctcct gtatccgggt
     2521 tgaaagtaac ctgaacagtc gatttcttat tgaaaagcgc cggagccaga tattcgatag
     2581 taccgaattg tgtgacagga agttctccgt taaaccattg ctttttcccc tccgttagtg
     2641 ttacttgtgc tttgccgggc acattatagg caatgccgtc caccttcttt ttgccatcgt
     2701 cttccggtac gttgacggtt ttcagattct tcagcgtgat ataaaccggc tctcctgcaa
     2761 gatcgttatt agcaactatg cccagcttct tcgaaaagcg gaaggctact tcgttgtcca
     2821 tttccttatc cggagtgagg cggatgttga atatcttttc gtctttattc aaggtacccg
     2881 agaacatttc ggtcatggca gcctcttgct cttccaggtt ggcgagcata atcttcagtt
     2941 gctccccatc tttgggcatg ttgtctgcct gtccgcgtac cagggcattt ttactttcac
     3001 gaatgttata aatctctttg gcaaccaact ccgccatttt agctgtagaa cctgccatca
     3061 gaatctcttc ggtcagaaaa tcacgtggat ttatcttctt tttctgtgtc gtggcgggtt
     3121 gcatcggagc cgacttttta ggagatagcg gtacgttgat tgattttacg ataccatctt
     3181 cggtcaattc tattagcgga gctactgttt tatctttcag cttgacaaaa taggtatgtt
     3241 cgctatcggg gataccgaca gattttgctt tgacgctgac cagttcccaa tattcctgag
     3301 gctcacccga cacatcggtc aaccggagat aacggtcggc atacttgctg aattctcccg
     3361 gagtatatgt cactttattg actttgactt caatattgat tgctgtttta ggaagtgcat
     3421 aggttacacc gtaatctttt ccccgggtaa ctcccgctgt aacttcggtc tgggcataag
     3481 ccgaggtaga gagtaacagc cctgtcagta taattagctt tttcatttcc ggtttatttt
     3541 aactggttta aaaaacaaag ttaatgaagt tatttggaaa atcataagtt gttaactttt
     3601 attcgcttac cagacgccaa gccaatggca gattactgat aatgtctcct gccgtcatgc
     3661 tgataacgcc ttgctttttg cgtgcgaaat cacctgccag accatgtaca taagtaccga
     3721 ttttggcagc ttcttcagcc ggatatccct gtgcgagcaa agccagcacg acacctgtca
     3781 atacatctcc gcttccggct gttgccatac ccggattacc cgtagagttg aaatagcact
     3841 tgcccgaggg ggtgataatt gccgaatagg ctccttttaa tatgatatgt actttggcgg
     3901 ttcgggccag ttcacaggcc ttcatcagtc gttcgtatga gttctggcat ttgcccacca
     3961 tgcgttccag ttctttggga tggggagtca gaatagagcc tttgggcaat gtggtcagtg
     4021 cgtggcggtg gttggccaat atgtttagtg catcggcatc cagtaccaga ggtgtctggc
     4081 aaccactgag ttgttcaagc agtgcagctt cggtctcttc cgagcgtccg atgcccggac
     4141 cgattcctac agcctgatag tcatccgtat ctgtagggca ggcaaagtag gtatcgctgg
     4201 catccgattc gataattgcc tccggaaccg aaatctgcag gatagcattg ttgcgtatag
     4261 gtgcatggac tgtcagtaag cctacacccg aacgcataca ggcgcgggct gccagtatcg
     4321 acgcgcctgc catgccgtac gaaccggcaa tcagcagagc atgcccaaag tttcctttgt
     4381 gtgagaaagt gttacggggt ttgatcagag tgtgtatttc ttccgcttcc aataaggcat
     4441 aattgctttc cgtttcttca atcgcttcac gactgaggtt gatatccaac agtttccatt
     4501 cgcctacgaa ttcggaattt tcggcaaaga ggaaagccag tttcggcaat tgcaggctca
     4561 atgtcaattg ggcacggatg atattggctt ttacattaaa tgtgttctct tctcccatca
     4621 gtcccgaggg gatatcgatg gcgactacgg tggcaggcga tgcattgata tatttcacta
     4681 ctgccgcaaa accgccactt agcggcttat taagtcccga accaaaaagt ccgtccacta
     4741 ccagatgatc catcgtcagg gcaggaggta caaactgtgt gcttacttcg ctgaacttca
     4801 cattatccat catctctacc agctccttgt tggtctggca gtcggcagac agttcccctt
     4861 tcgggttaaa cagataggct tcgaccttgt attccttttc cgccaacatt cgggccacgg
     4921 caagggcatc tccgccattg ttgcccggtc cggcaaatac cgtgacggga gttgtgatgt
     4981 cccagcgttc ggtgatggct ttggtcaatg cctgtgcggc ccgctccatc aggtcgatcg
     5041 atgcaatcgg ttcatgttct atggtgtaag catccagttt cttgatgctg ctacttggaa
     5101 aaatcttcat ggtgaacttt cattttaagt tttttgaccc acaaagatag caattaatat
     5161 acgaaatcgg gaacttcttt ttcttcttct ttttttctga atacccctgt ctttccgtaa
     5221 ttctccctgc ggtagcgttg gtgcaggtag atgaaagagc atacaaaagc aacgaaacag
     5281 attattccca catatcctgc catcagattg tagaaagctg tccagttaat gtccggtgaa
     5341 aagaattctt tgacagccaa tactatgact gttcccgtat agcccagaaa atcattcata
     5401 gcaatgaaga aacccacgtt acctcgaatt ttgaagcaag cgataaaacg gtcgaagaag
     5461 atagtctgga aagtgagaaa agccagatag agacacaggc tctggatgaa tagccaggcg
     5521 atggcgttca gctgcaattg ttcgtaacca aacgaaacga ctgccatcac taccatgctg
     5581 gcaatgatca atcccagtaa tatcgacagt gctttcaagt tgcttctgac gaacaccatt
     5641 aatccgaaaa ttatcagaat aatgagggtt actacgctgt ctacctgtgc aaacatccac
     5701 gaagagtatt gagagacatc gataattttt accaggaagt cctcctttat atctctcaag
     5761 atagtcagta ccacattggc tataaagagc agagtgagga aaggcatgaa attcttaaat
     5821 agctcccatc gttgcttgcc gttcagtgtt tcccgtttcg atttcatggc aatgtcttcg
     5881 gctgttggct gtggaagccg gttgagagca taccccaaca aggcaagtag aggaagggca
     5941 actccgccta tcagggcagg catccagaat tcgctgatgt tcaaagtgtc catgacatac
     6001 aaaccggccg acttggcggt acccgagctg atgaccatac tgactccgag taagctggca
     6061 agaatgtccg tcattcgtct tccctcgata aagctaaaaa tgattcccca catacatccc
     6121 agtgaaagtc cgttcagaaa catggctcct atattataag gtgcgggcaa cagtccgaac
     6181 aatattaacg aagcttcagc cagaattatg gagatcagaa taaacttcat ccggttttcc
     6241 cgttttaatt cggagattaa tttaattccg atgaatttag aaagtacata tcctaatatt
     6301 tgtgcgatgg taactaccac tttgtagtcc attccaaacg cttcaagtcc gtcaaatccg
     6361 gctgctgtat aaggctttct cagtgcatat accaatgaat aggagagcag cgctgctccg
     6421 cctgcccaaa gaatgaaaag gaaatcagaa atttttctct gcgaataagt ttttacttgc
     6481 tgtacattgt tcataacatc tgcttgttgt tttccggtgc aaaaatagga gggtagtgtt
     6541 acagacctgt tactgaatat atgaatgttt attattaata gatattgata atgaatctgt
     6601 tatgttgtaa tgtttatgta atatttatga aacggaaacg aaaagagcat cgcacctccg
     6661 ggcatctgtt cgtcataatt ttaacgggaa gcagatgcat acctgcaaat atcttttagg
     6721 aaataaattc cctatttctg ggtattgcct gtttgggcag aaactgtact tttgcctgaa
     6781 atattaaatc agcagacaaa tgaataagag aggctttgta agcaggatct tacagaattt
     6841 ccggaagcct gaaggttttt tcggaagaat gatactttgg gggatgaata caggacatgc
     6901 atcattggcg caatggggaa tgtcatgctt gcaatggcaa ccggaatgga gtgtactcga
     6961 catcggttgc ggtggtgcca atttgctaca gatattgcaa cgttgcccgc aagggaaagc
     7021 gtatggcata gatatttcac cggagagtgt cacctttgcg cgtaaaaaaa ataaaaagta
     7081 tctcggtaca cgctgcttta tcgagcaggg aggagtccac cgacttccct atcctgatta
     7141 tgcgttcgat gcggtcactg ctttcgagac tgtctacttc tggggtaacc tgcagcatgc
     7201 ttttacggaa gtggcgcgtg tgttaaagcc cggtggatcg tttcttatct gttgtgagat
     7261 aagcgatcct gccaataagg cttggacggg acttgttgaa gggatggaga ttcattcctg
     7321 tgatgaactg aaggcgattc tttccaaaag tggttttacc gatacggtca tattccggac
     7381 gaagaaagaa gaactgtgcc tggtaagcca tcggcaaact gtgcggttgt aatcaatgcc
     7441 gggacgctct taccaacgaa tacgttaaca atgttaatgc ccgtaagagt gctttccctc
     7501 cttatcaata gcttattaac ttcgtatctc taaagaatta atatcttgca attacgaagt
     7561 taatattaac gtactgttaa tgttaacttc ctacagttct cttattaaga tattattgtt
     7621 tgataatcaa ttgcttatat tctggatgcg ttctgccgta aaattcttct cttacgttca
     7681 agatgtgcgt agttgtctgt ttatcaagtt accgttaaga ctctccatag cctgcctctc
     7741 cacttatttc cacattcttt tataagccat attagtatta tgtatattgc tgctttcctt
     7801 atttgcaaag agataaatta tgtctttgat attcagtcat ataacttcct atgatgaaaa
     7861 taacctgtga aaagttttgg agactcaaaa gaaggtttta cctttgcacc cgtaaatata
     7921 taggcggaca aatatacttt tctttatgtc cgatatatgt ttaaaataaa ataattcaac
     7981 gtatcggata gtattcaaat ccggtgcgaa tactttttct gtacccgatt atcataaaac
     8041 ttaatttgta aattgctgaa aataaggcat gttttttgaa tattcctgtt tttaacaaat
     8101 tttcatcctt agtcattgct gaaacttttt cttacgaacg tagtcttgga gacaacagat
     8161 agcgataaac attggtatgt cgtactgaca cgaactaact cagaacgtaa agttcgggat
     8221 tattttcaat tgcaggaggt agataccttt cttcctgtac aaaaccgtgt catagagcgt
     8281 gaaggaaaac gcattgagcg tgagcgcctt ttgttgcccc gtatggtttt cgttcatatc
     8341 tcccgtcagg aaatggctgc cgtccgaagt acactgaatg tatacgattt ccttcgtgat
     8401 cgttccaccg gggctcctac ctgtatccct gatgcgcaaa tggctgattt tcgctatatg
     8461 ctcgattact cccaggatca ggtgatcctg acaggagagt ccattcccaa aggtactcgt
     8521 gtagtagttg ccaagggcga tttacaaggc ttgcggggag aattggtccg ctataataat
     8581 aaatatcata ttttagtacg tatcgatatg ttcggtagcg ctatggttac aattccggct
     8641 agctacgtcc ggaaagagaa ataaaaagta tatatgtaaa gaaaatacca ttatatgtaa
     8701 tggcgataac aatatatgta acgggtgata acaatatatg taatgtcccg ttacgtcgtt
     8761 agatacaatt ctattggata ttattactct tctatacaaa taaaaaccga aaagaatcga
     8821 cgaatcataa ttcattcctt tttaaaatga aaaattctct gtgtaattct gtgtcctccg
     8881 tagtgaagaa actcttggag tatggcgagg acggtactcc tgtctatgtg aatgaactta
     8941 ctgcgttaaa tcaagaactc cgtaacttgt gtgctgatct tcttcttcag aaaggagaat
     9001 ctcccgaaga agaggctgaa atacttgtta ctttgttcaa aggttacgat accatgctgt
     9061 ttaatttctc ctctgagaat gaacaggtta ttcaagaatt attggatcgt tcaatgactg
     9121 ttttagaaaa actaccagcc tctgtattga aatgtcagtt gctgctggag tgctttgagc
     9181 agacgggaga tgaggaactg ataactagct tagggaccgt tttggatgtc atgagtataa
     9241 tgtaagtcag ggataaacct ttttttagtg aattttttac aatcaataga gagttatgtt
     9301 gttccaaact gtaaaagtct aattaatgga atttatttct tttattagaa tattgtttat
     9361 aaatccttat taaatgaata aagggggcaa acatattgca aagaatactg tgatattgta
     9421 tttacgtatg atggtaacta tgttggttac attatatacg tcgaggatta tattagaaag
     9481 tcttggaatt gaagattatg gtatttataa tgttgtagga ggagttgtca cattattttc
     9541 atttataaat ggtgcaatga caagtgcaac tcagagatat ataacttttg ccatagggaa
     9601 aggcgatgca ataggacttc ctaaagtatt ttgcattagt cttttatcac atatttctat
     9661 aatagctata gtattgttct tttcggaaac tattggatta tggtttttaa actcttatat
     9721 aagtatacct aatggaaaaa tagtagaggc taacttggtc taccaatttt caattttggc
     9781 tttttgcttt cagattataa aggttccata tgacgcgaat ataattgcac aagagaaaat
     9841 gtccatttat gcatatgtaa gtattgcaga agtaataatg aagctttgta ttgctttctt
     9901 gttgcaattg ttttttagtg atagacttgt tttatatgct ttcttgatat ttttttcgtc
     9961 tgttttattt ttctttttaa acaaattttt ttgtttgaag atgtatccat attgtaaata
    10021 tcatttctat tgggataagg atatatataa agaattaatg agtttttctg gttggagttt
    10081 ccttggtcaa gtcgctattg tattttctag tcaggggaat aatatattat taaatatgtt
    10141 ttatggagta gttgtcaatg cggcattagg aatttcaaat caagtaaatt ctgcactgat
    10201 gagttttgtt agtaattttc agacagcttt taagcctcag ataactaagt cttatgcaaa
    10261 taatgatttt gaatatcttt tcaatatgat gttttataca tctaaaatgt cattctattt
    10321 gatatattta ttggctattc caattatttt taatatagat gctattttga attgttggct
    10381 aactgttgtt ccaacttata ctgccaattt ttgtatatta atgattattt attcattact
    10441 tgatgctgtg accggtcctt tttggatggc tatttttgca actggaaaaa taaagaaata
    10501 tcaaataata ttgagtgtgt ttattttttc tagtattatc ttgtcttact tttcacttta
    10561 ttttggagga tctccggaaa gtgtgttatg gataagagtt ggtataaatg tcttagtatt
    10621 gttgattaga gtctattttg taaaatattt gttgggagtt cctttagagc tttttttgca
    10681 taaagtgtta cttccagttg gttatgtcgt tatattaagt attcctttat cttatctagt
    10741 atacatgcaa atttataatt ttcattttat ttttattctt gttgtaatat tactattaaa
    10801 tggagttata gtaatgtttg ctggtataaa taagaatgaa agaagacaaa tatgtaatat
    10861 ggtatataat ttaaaactta aaagagtgta aatatggaat ctcatgatat cggtttctat
    10921 tgggatgact ttgaggttgg gaagacattt gttcatagcc tttctaaaac gatttttgaa
    10981 agtgataata atcttttttg tcttttgaca atgaattatc atcctgtaca tacaaatgtt
    11041 gattatgctg ctaagaacca acatggtaga atattagttg ttggaacatt agttttctct
    11101 ttggttgttg gaatgactgt tcctgatatt agtggcaaag caattgctaa tttatgctat
    11161 gaagatattc aacacttggg tcctgtattt attggagata ccatatattc taaaacaata
    11221 attcttgaaa agtatccttc caattctaaa aaggatagag gaattgttta tgtgaagact
    11281 attggatata atcagaatgg agaggaagtt ataagtttta agcgtaaagt tttagtaaaa
    11341 cgaagagaat atgagtcatc tatttagaag tttgatgttt gtgcctgctc ataatgagcg
    11401 cttattgaat agtgcatcta gatcggatgc agatgtatta attttagaca tagaagattc
    11461 tgttcaacca gtgtcgaata agatagtagc acgaaataat attgttaaat atattagtgg
    11521 taatattttt tttgaccgtc ctatctatcc tagaattaat gatagagaaa gtggtgaatt
    11581 attgaaagat atttatgcgt taacaattcc aggtgtttcg ggatttatgt atcctaaatc
    11641 gactaaagga gaagatatat attttattgg taagctgtta gaaactgtag agtatgaaaa
    11701 aggttttcct attggaactt ttaaaataat tcctttgata gaaactgcag gggcaattgt
    11761 taacttgaaa gatatttgta cggcatgttc cagagttgtg gctgttgctt ttggttgtga
    11821 agattatgtg acagatttac gtggagaaca tgatgagaaa ggagaaagta tatttatggc
    11881 tagatcttta atctcagctt gtgctagagc ttgtaacatt tatccaattg atactgttca
    11941 tatcaaggta catgatttag aggatctaga gaaaaatttg attttgtcta aaaaattagg
    12001 atttgaaggt atgcttgtat taaatcctaa agaattacca ttggtacaca gatatttttc
    12061 tcctactcaa gaagaagttg agtgggcgaa agagatgtta gcgttagcgt ctgattctgt
    12121 tagtgaaggc aaaggagttg cagtcaaggg agacaaattc ataggtcctc caatggtaaa
    12181 aatggctaat aatatactga tgaagcaaca attaataaga gaaaaagtac aatgataact
    12241 tttgatagtt tgcgtaatga tttaaaggcg ctaggggttt ccagtggtga tttgcttttt
    12301 ttacgaatat cttataaagc tattggaagg gtagaag
//
