LOCUS       c00169_gnlPro..         3440 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OCCIACMC_169.
ACCESSION   c00169_gnlPro..
VERSION     c00169_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 14:57:06
            Original ID  :: gnl|Prokka|OCCIACMC_169
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3440
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..381
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_1"
                     /sec_met_domain="ILVD_EDD (E-value: 5.2e-52, bitscore:
                     165.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGT
                     SGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRYV
                     PKSLKAYASMVSSADKGAVRII"
     protocluster    1..3440
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2805]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2805
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3440
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3440
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(306..455)
                     /locus_tag="ctg169_2"
                     /transl_table=11
                     /translation="MTVENEWFTIIALSAAQLTITYQLYYIILTAPLSAELTMLAYAFR
                     LFGT"
     CDS             496..2190
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.5e-48, bitscore:
                     150.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLITGAEALMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNIL
                     NHILVRHEQGAAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQ
                     VGTGFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDF
                     AKNAQVEKTKYEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNA
                     QSELREFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGM
                     RFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKNTH
                     TEWIDSFKEYEKVEEEKVIRPELHPATNSLSMGEVVRAVSDATHHEAVLVTDVGQNQMI
                     SARYFKYTKERSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGT
                     IMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKVASAYDIPSKRAFT
                     REELKEAIAEMLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             2248..2805
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_4"
                     /sec_met_domain="ALS_ss_C (E-value: 9.9e-20, bitscore:
                     59.1, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDIIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQENP
                     EASKLIRRYNARIVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQ"
     CDS             2811..3440
                     /locus_tag="ctg169_5"
                     /transl_table=11
                     /translation="MNEENRIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHANDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESY"
ORIGIN
        1 gtcgtcatta cgcacgaagg tccgaagggt ggtcccggta tgcaggaaat gctttatcct
       61 acctcttata tcaaatctcg tcatctcgga aaagaatgtg ctttgattac cgacggacgt
      121 ttcagtggtg gaacttccgg attgagtatc ggacatattt ctcctgaagc ggcagctgga
      181 ggcaatatcg gaaaaattgt agacggagac attatcgaaa tcgatattcc ggcccggaag
      241 attaacgtgc gactgacgga tgaagaactg gcggcccgtc cgatgactcc tgtcactcgt
      301 gaccgttatg taccgaagag cctgaaggcg tatgccagca tggtaagctc tgccgataag
      361 ggagcagtga gaattatata atatagttga taggtaatag ttagctgcgc agcacttagc
      421 gcaatgattg taaaccattc attttcaact gtcatttctc aactatcatt tatcatttat
      481 caactatcaa ctaatatgaa agatttaata acaggtgcag aggctttgat gcgctccttg
      541 gaacatcagg gagtgactac catctttggt taccccggtg gttctattat gccggtattc
      601 gatgccttgt acgatcatca aaatatattg aaccatatct tggttcgtca cgagcaggga
      661 gccgcccatg ccgcacaagg ttatgcccgt gtatcgggtg atgtaggtgt ttgcctggtg
      721 acgagcggtc ccggagcaac caatacggta acaggcattg cggatgcgat gatcgatagt
      781 acgcctatcg tggtgattgc cggacaggta ggaacaggct ttcttgggac ggatgctttt
      841 caggaagttg acttggtagg tatcacccag ccaatcacta aatggagtta tcagattcgc
      901 cgtgcggaag atgtagcctg ggcggtagca cgtgcgtttt acattgcccg tagtggtcgt
      961 ccgggtccgg tggtattgga ctttgccaaa aatgcgcaag tagagaaaac gaaatacgaa
     1021 ccgacgaaag tcgattttat ccgtagttat gttcctgttc ccgatacgga cgaggagact
     1081 gtacaggctg ctgccgaact gattaataac gctgaacgtc cgcttgtatt ggttggacaa
     1141 ggtgttgaac tgggaaatgc acagagcgaa ttgcgcgagt ttatcgaaaa agcggatatg
     1201 cctgcgggtt gtacgctgct cggactttcg gctttgccga cagaacatcc gttgaataaa
     1261 ggtatgttgg gtatgcacgg caatctggga ccgaatatca ataccaataa atgcgatgtg
     1321 ctgattgctg ttggtatgcg ttttgacgac cgtgtgaccg gtaatttggc tacttatgcc
     1381 aaacaggcaa aagtgattca ttttgatatc gatcctgcgg aagttaataa gaatgtaaag
     1441 gtagatgtag ctgtattggg agattgcaag gaaacactgg cttctgtgac gaaacttctg
     1501 aaaaagaaca ctcataccga atggattgat agcttcaaag aatatgagaa agtggaggag
     1561 gaaaaagtaa tccgtcccga acttcatcct gccacaaact ctttgagtat gggggaagtg
     1621 gtacgtgcgg ttagtgatgc tactcaccat gaagctgttt tggtaacaga tgtaggtcaa
     1681 aatcagatga tatctgcacg ctactttaaa tatacgaaag aacgcagtat cattacttcc
     1741 ggaggacttg gaacaatggg cttcgggctt cccgcagcta tcggggcaac tttcggagca
     1801 ccggaacgta ccgtatgcgt atttatggga gatggcggac tgcaaatgaa tattcaggaa
     1861 ctgggtacga ttatggagca gaaggctccg gtgaagatta tctgcctgaa caataattac
     1921 ctaggaaacg tacgtcagtg gcaagctatg tttttcaacc gtcgctattc gtttaccccg
     1981 atgttgaatc cggattatat gaaagtggcc tcggcttatg atattccttc caaacgtgct
     2041 ttcactcgtg aagaactgaa ggaagctatt gctgaaatgc tggcaacgga cggtccgttc
     2101 ctgctcgaag cttgcgtggt ggaagaaggc aatgttttgc cgatgactcc tccaggtggt
     2161 tcggtaaacc agatgttgct ggagtgctag gagaagttga gagttgagaa tggagagttg
     2221 agggttcgca tttaaaaaat tagagttatg agtgataaaa cgttatatac aatcattgtt
     2281 cattcggaga atatagccgg gttgctgaat caggtaactg ctgtatttac ccgtcggcaa
     2341 ataaatattg agagtctgaa tgtatctgct tcttctatta aaggtgtaca taagtataca
     2401 ataacagcct ggactgataa ggacatcatt gagaaggtag tgaaacagat cgaaaagaag
     2461 atcgacgtga ttcaggcaca ttatttcaca gaggatgaaa tttatttcca cgagattgca
     2521 ttatataagg tgtctactcc tgcttttcag gagaatccgg aagcatccaa gctgatccgt
     2581 agatacaatg cacgtatagt ggaagtcaat ccggtatttt ccattgtcga gaaaaatgga
     2641 atgagcgaag atataacttc gctctatggt gaactgaagg ctttgaattg tgttttgcag
     2701 tttgttcgtt cgggacgtgt agcgattact accagctgtt ttgaacgggt gaatgagttt
     2761 ctcgatggac gggaagctat gtataaccaa agtaaaaacc aataagaata atgaatgaag
     2821 aaaatagaat agggacttat cagtttgtgg cagaaccgtt ccatgttgac ttcaacggac
     2881 gtttgactat gggggtactg ggaaatcatc tgctgaattg tgcaggtttt cacgccaatg
     2941 accgtggttt tggtattgca acgctgaatg aggacaatta tacatgggtg ctttcacgtc
     3001 tggctattga gttggatgaa atgccttatc agtatgagaa tttctcggtt cagacgtggg
     3061 tggaaaatgt ctaccgcttg tttacggacc gtaattttgc tattattgat aaggatggga
     3121 agaagattgg ctacgcacgt tccgtatggg caatgattaa tcttaatacc cgcaagcctg
     3181 ccgacttgtt gactttgcat gggggaagta tcgtagacta tgtctgtgat gagccttgtc
     3241 cgattgaaaa gccttcacgc atcaaagtga caagcgatca gccaatagct accctgacgg
     3301 caaaatacag tgatatagat atcaacggtc atgtaaacag catccgttac atcgagcata
     3361 tccttgattt gttcccgatt gaattgtata agaccaagcg tatccgtcgt tttgaaatgg
     3421 catatgtagc cgaaagctat
//
