LOCUS       gnlProkkaILDBNLHE_77   11807 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILDBNLHE_77.
ACCESSION   gnlProkkaILDBNLHE_77
VERSION     gnlProkkaILDBNLHE_77
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 12:09:01
            Original ID  :: gnl|Prokka|ILDBNLHE_77
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11807
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11807
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2533:6807]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2534..6807
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11807
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11807
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..136
                     /locus_tag="ctg77_1"
                     /transl_table=11
                     /translation="MKKFFVQLLYNIHFFIEKKLKNAVSKDERFLKHIRSFSTSKNVS"
     CDS             227..751
                     /locus_tag="ctg77_2"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             755..1240
                     /locus_tag="ctg77_3"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             1237..2520
                     /locus_tag="ctg77_4"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWIPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAAFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             2534..3232
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-14, bitscore:
                     44.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDNFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             3171..4553
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.7;
                     E-value: 2.7e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_6"
                     /sec_met_domain="CTP_transf_like (E-value: 4.3e-13,
                     bitscore: 39.7, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.5e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8.2e-65, bitscore:
                     208.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSMMKPTFRMPRSTSSAIVKNKSFPYMNKKIYVGMTADIMHPGL
                     IHIIHEATKYGDVIVGLLTDKAIAEHKRLPYLTYDQRKEVVENIKGVCEVVPQEDWSYV
                     PNLEKLKPDYIIHGDDWKTGPLREVREQVFEVMNAQGGKVIEIPYTRGINSSSLDKDIK
                     AIGTTPDVRLKSLRRLIQAKPVVRILEAHDGLCGLIIENLEVQKGDKREVFDGMWSSSL
                     TDSTSKGKPDIEAVDLTTRLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGI
                     SAVIIEDKVGLKKNSLFGTDAIQTQDSIEGFCDKIRAGKNAQVTGDFMIIARIESLIAG
                     KPMSDALERAYAYVQAGADGIMIHSKDKSGEDIREFCRTFRKEYAHVPIVVVPTTYDHV
                     HESELHEWGANVVIYANHLLRAAYPAMMNVARTILENERAEEVRPLCMPIKEILELIPV
                     TK"
     CDS             4565..5701
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_7"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.3e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             5698..6807
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 4.5e-34.
                     Score: 109.8. Matches aSDomain:
                     nrpspksdomains_ctg77_8_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 81.8; E-value:
                     7.7e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg77_8"
                     /sec_met_domain="Aminotran_5 (E-value: 1.1e-31, bitscore:
                     100.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKALSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMKSVNTVLVNK"
     aSDomain        5788..6576
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg77_8_Aminotran_5.1"
                     /evalue="4.50E-34"
                     /label="ctg77_8_Aminotran_5.1"
                     /locus_tag="ctg77_8"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.8"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKALSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             6820..7638
                     /locus_tag="ctg77_9"
                     /transl_table=11
                     /translation="MLKKRLDYSQLKVIQLNILKDVDAFCRENNITYYLTYGTLLGAVR
                     HQGYIPWDDDIDIAMPRKDYEKFLSNYNLNGSKKNVYQVVAIELNNAYPYPFGKVQDLS
                     TVLLEYSDINYPLGINIDIFPIDGLPVDLKKSDKHFLKIKWLMMIMNLKKVKITIKRSF
                     LKNLILLIGKILTLLIPYRFIVCKMSYIAQRYDYEKSDYVSNLSCPDGKHERTSKRVFE
                     NSIEILFEGNNFYAPIGYHEWLHNIYGDYMKMPPVPERVSHHKFEIYKIL"
     CDS             7641..8636
                     /locus_tag="ctg77_10"
                     /transl_table=11
                     /translation="MCSKDNFLQEVRALCIFTVILLHVPFQGHDNISFNTWLMSKQLIT
                     FPVAVFFFLSGYFYSFRNYKSRIVKLLCPFLFWNMSVHLIKFIRGESGFNIENFLLGNG
                     LPYYYLAVLLQIVLFHYIIFKYWSEMVYRVLSISISIISLMAYYYFSISYSIHFNCYLY
                     FPFWILFYTLGTFGKKYWRNLISKIPFCVILLFILISVFLMFFEANLMYYILFQEGIAG
                     SQVKFSSWVYSILIVLLLLKIDYSIDENVTRNFGTLIGDYSYGVYLIHIFILSLIYKLC
                     IVVFNDNYNVLLPFIAASITLVISVFMIYILNKCLPPFILKFLGLYVKSN"
     CDS             8620..9792
                     /locus_tag="ctg77_11"
                     /transl_table=11
                     /translation="MLKVTDECTACGACLSICPKNCISFKSNEEGFLYPHIDIEKCVDC
                     DLCSKVCFLNDHITPTFRENDISYYAAKAIERCNLSSSGGIFPLLAESVLKNDGVVIGA
                     AWDDKFNVKHILIKSKSELPLLCGSKYIQSNTEKVFKIVKEHLSIQTVLFSGTPCQVKG
                     LKTFLGKDYDNLITVELVCHGVPSPLVFRRYLNGVLKYNNLDISQCSKINFREVKDDIY
                     RFVIYNKTKIPFYEQYTNLYTKTFLQNLFLRNSCYNCKCKLENSVGDFILGDFWGCRDF
                     YPEFYDPKGVSLVIVCTERAKKIWLNLKLSRIEVKKKIVFRSNRHLLKSASYNRNRDLF
                     FKTFIHEAEISLDDILMGYTNKDIWVKVKGLIISVLRFVGLFQLVQLYRK"
     CDS             9789..10847
                     /locus_tag="ctg77_12"
                     /transl_table=11
                     /translation="MKIALLTLPFVNNYGGILQAYALKHFLELRGHSVCIIDRNSNFKI
                     SFIDILRLAKRKFLGNRIRNFAYFKKQYLLPMTSEIITNKEMLLLDEKYQFDIYIVGSD
                     QVWRAIYYRDIKYNFYLDFVSSKRKISFAASFGISSWEYTNTETDIIAKLLMDFSFVSV
                     REDTAVRLCSDYLNINAVQFLDPTFLLDKNEYCCLADCFYSSKKIDIFAYIMGPDSSKD
                     KLIKIISDYSGLSVQSITQSKFSFKKNESIQEWLQNFYKSKFVVTDSFHGLAFSLIFNK
                     PFIVCGFSNRGMGRYESLLRYFSLENRLLYSLEDLKELNLSTIWDINWKEVNAKIAENK
                     RFVLELMQTVGV"
ORIGIN
        1 gcaaaaaaag ttctttgttc agctacttta caatattcat tttttcatcg aaaaaaaact
       61 caaaaatgct gtttcaaaag acgaacgttt tttgaaacac attcgttcgt tctcaacttc
      121 taaaaatgtt tcgtaaaatt tgacggtttg aaagagaaaa gatgtctcgt tcaaaccgcg
      181 aagcgcaccc gaaataaagg aaaatttccc caagtataaa tcgtaaatgt ctgaacaaca
      241 gaagtattgg tttgccgccc gtacccgaga taaacaagag tttgctattc gtgactctct
      301 tgaaaaattg aagactgaac ttgatctcaa ttactatctt cccactcagt ttgtcatccg
      361 gcagttgaaa tatcgtcgaa aacgggtgga agtccctgtt attaagaatc ttatcttcat
      421 ccaagctacc aagcaagatg cttgtgatat ttctaataaa tacaatatcc agctttttta
      481 tatgaaagac ctgcttacca gggctatgct gatagttcct gataaacaga tgcaggactt
      541 catatttgtc atggatttag atccgaatgg cgtcagtttc gataatgacc atttatctgt
      601 cggtagcagg gttcaggtag ttaaaggtga tttctgtggt gtcgagggcg aacttgccag
      661 cgaggccaac aaaacttatg ttgttattcg tattgccggt gtattgagcg ccagcgtcaa
      721 agttcctaaa agttatttac gtgtcattta agttatgaat acactcactt ctcaaattga
      781 acaattacag agtctcgcgc acgagttact ctatttaggt gtggatggtg ctcctattta
      841 taccgatcat ttccgtcagt tgaacaaaga agttttagaa caatccgatg cgttgtatcc
      901 tcagcgtggt gctactcccg aagaggaagc aaacatctgt ctggcattat tgatgggtta
      961 caatgcaacc atctataatc agggtgacaa ggaggagaaa aagcaagttg ttctcaatcg
     1021 ttgttgggac gtgcttgacc aacttcctgc tactttattg aaatgccagt tgttgactta
     1081 ttgttatggt gaggtgtttg aagaggagtt ggcgaaagag gcgcatacta tcatagaaag
     1141 ttggagcaat cgagaacttt taaaagctga aaaagaaata gctgaaagtt tgaataattt
     1201 ggaagctaat ccatatccgt acagcgaact acacgaatga ttcgttcctt tctttcccgt
     1261 tctccccttt acgttttggc tctctatgcc agcgttttga tttttctggt ttatacttgt
     1321 gcctatgcct accgtaagcc atttaccgca gccatttatg aaggtgagat tctttgggga
     1381 ttcgatgtca aaatcctgta tgtcctttct gagattatcg gctacgccct ttccaagttc
     1441 atcggtgttc gtattctgcc ttcgatgaaa gcgggtcacc gcatctatta tataataggg
     1501 ctgcttactt tttccgaagt tgctttgttg ggttttgcac ttcttccggt tcctttgaag
     1561 gtgtgttcta tttttctgag cggtcttccc ctgggtatga tctggggtgt catttttagc
     1621 tatatcgaag gacgtcgtat cagtgaaata ttgaatgtcg ggctgagcgt tgctttgata
     1681 gtctcttccg gtttggtgaa aaccttggga caattcgtga tggataattt gcatgtgtcg
     1741 gaatattgga taccttttac caccggtttg ttggtatacc ctgttatgtt gctttgcagc
     1801 tggcttctca atcagattcc ggctcccaat gagcaagata tcatacagcg taccaaacgt
     1861 gctccgatgg atggtaaaga caggcgtaaa tttttgaggc aattcttctg gggaatctgc
     1921 atgctggttg ttttttacgg tgccctgacc gtgttccgtg agcttcgtga ctctttcgct
     1981 gccgatattt ggaaggagct ccatattgag ggtgcaatga tctttactca gacagaggtt
     2041 cccattgccg cttttgtcct tgtactgatg ttcctgattg tgtttgtccg taataaccgt
     2101 ttggctctta atatcattta ttgcattgcc gtcacaggcg gttccttaat ggttttttcc
     2161 acattgcttt atgtgtacgg ttttctttct cctatttggt ggatgattct ttccggtctt
     2221 ggtctgtata tggggtatat tcctttcact tacctgatag aacgcctgat tgcttccctt
     2281 agggtggtta gtacggctgt ttttattatt tatttggccg attctttcgg ctatctgggc
     2341 actacgggtg tgtttatggt caagaacttc gtttctgctg acatttcctg gactgtcatg
     2401 ctaatgcgta ctgccctttt ttcaggattt gtttctgtcc tgtcgatttt tgcgatttac
     2461 tgttatttca agcaacaatt gaattcactt atattaattc cctctgaaat tcatgattaa
     2521 aacagcaatg atcatggctg ccggtcttgg tacccgcttc gggcattata ccgagcttgt
     2581 gcccaaaggt tttgtggagg ttggtggaaa acctatgatt atccgctcta tcgaaaccct
     2641 tctttcctgc ggtatcgaac gtatcatcct cggtacgggt tataaaaaag aggcttatga
     2701 agcccttcag gcggatttcc cccagataga gacctgtttc agtccccgtt atgccgatac
     2761 taacagtatg tacactctgt acaatacgcg tgacgtgata ggcgatgaca atttcctgct
     2821 gcttgaatcg gaccttgttt ttgaacgcaa ggccatcctc tcgctactgg atgacgaatt
     2881 cccggatgtg atgcttgtct cttctctgac caagttccag gatcagtatt atgtggaata
     2941 tgaccgcaat cacatcctta cttcctgttc ggtagacaag aacgcccttg aggcaaaagg
     3001 cgagctggtc ggtatccata aactttccaa tactttctac cgccggatgt gcgccgatta
     3061 tgcgaccatc ctggagtccc agcctaaact gggttacgag tacgaactgc tccgcatgtc
     3121 ccgttccgtt tcccctgtcc gtgtgctcag ggtggagggt cttaaatggt atgaaatcga
     3181 tgatgaagcc gacctttcgt atgccgagga gcacatcatc cgctattgtt aaaaacaaat
     3241 cttttccata tatgaacaag aaaatctatg tcggtatgac cgcggatatc atgcatccgg
     3301 ggctgatcca tattattcat gaagctacta aatacggtga tgtcatcgtc ggtctgctga
     3361 cggacaaggc catcgccgaa cacaaacgcc tcccttacct tacctatgat cagcgtaagg
     3421 aggttgttga gaatatcaag ggggtttgcg aggttgttcc ccaggaggat tggagctatg
     3481 ttccgaatct ggaaaaactc aagcctgact atatcatcca cggtgacgac tggaaaacgg
     3541 gtccgttgcg cgaggtgcgc gaacaggttt ttgaggtgat gaacgcccag gggggcaagg
     3601 taatcgagat cccttatacc cggggcatca actcctcctc gctcgacaag gatatcaagg
     3661 cgatcgggac tacccctgac gtacgtctta agtccctccg ccgcctgatc caggccaagc
     3721 ctgtggtccg tatcctggag gctcacgacg gtctttgcgg tctgattatt gagaatcttg
     3781 aagtccagaa gggtgataag cgcgaggtct ttgacggcat gtggtccagc agcctgaccg
     3841 actccacgag taagggtaaa ccggatattg aagcggtcga ccttaccacc cgtttacagg
     3901 acctgaacaa tatccttgaa tgtaccacca agcctattat ttttgatgga gacacgggtg
     3961 gcaagatcga acactttgtc tttactgtgc gcactctgga acgtcacggc atttctgcgg
     4021 taatcattga agataaagtc ggtctgaaga agaattccct ttttggtact gacgctatcc
     4081 agactcagga tagtatcgag ggtttctgcg ataagatcag agcagggaag aatgcccagg
     4141 tcaccggtga ctttatgatc attgcgcgta tcgaaagcct tattgccggc aaacccatga
     4201 gtgacgccct cgaacgtgct tatgcctatg tacaggcggg tgcggacggc atcatgatcc
     4261 acagcaagga taagtcgggt gaggatatcc gtgagttctg ccggactttc cgcaaagaat
     4321 acgcccatgt tcccattgtc gttgttccga cgacttatga ccatgtgcac gaatccgaac
     4381 ttcacgaatg gggtgccaac gtagtcattt acgccaacca ccttctccgt gccgcttatc
     4441 cggccatgat gaacgtggcc aggaccatcc ttgaaaacga gcgcgccgag gaggtccgtc
     4501 cgctttgtat gcctatcaag gaaattctgg aattgattcc ggtcactaaa taaatcagac
     4561 ggttatggta agtgtagaaa agatatacga tacgttcctt catcacggtg ttgacttctt
     4621 tacgggtgtt cccgattccc ttttgaagaa tatttgcgcc tatatcacgg atcatgctcc
     4681 gcgtggtaag catatcatcg ccgctaatga aggttccgcg gtgggcattg cctgcggtta
     4741 ttatatggct tctggcaacg ttcctttggt ttatatgcag aactccggtc tgggaaatac
     4801 ggtgaatccc ctcttgtccc ttgcggacga gaaagtgtac agccttcctc ttcttttgct
     4861 ggtcggctgg cgcggtgagc ccggcacaaa agacgaaccc cagcataaga agcagggcga
     4921 ggttaccctt gatcttctga aagccatgaa aattcctttt ataattctgg atacggatga
     4981 agacgaggcc ctggcgcaga tccatgacgc ggttgtctcg gcgaagagcc ggtcgattcc
     5041 ccatgcgatt gtcatccgta aagatacgtt tggaaaatat aaattgcgtc aggaagcctt
     5101 gaatgactat cctctgtccc gcgaggaggc gctaatgcag gttgtcgacc acctcgggga
     5161 caatgacatt gtggtttcca ccacgggcaa gctctcccgt gagcttttcg agtaccgtga
     5221 atcgaaaggg caggggcacg caagggattt cctaactgtg ggttccatgg gtcacagttc
     5281 ttccattgcc ctggggattg cccttgagaa gcctgaccgc cgtgtctact gtcttgacgg
     5341 tgacggtgcc tttatcatgc acatgggtgc tgtcagcaat atcggcgatc tttctcccaa
     5401 gaattacagg cacgtccttt tcaacaacgg tgcgcatgaa tctgtcggcg gtcaacccac
     5461 gctcggtttc cgtctggata tcgcctcgat agcgaaaggt tgcggttatg cgcatgtact
     5521 gactgcctcc gacaaggaag ggctttcgtg tgcgcttgag aagctgtccg gcctgtccgg
     5581 cccggttctt cttgaaatta aggtccggat cgattcacgt gatgatctgg gtcgccctac
     5641 gactactccg gtagagaata aagagcattt tatggcattt ttaaaagata cgcattcatg
     5701 aatatcgaaa gaaagatcct tttgaatccg ggtcccgcca ccacgacgga tacggtgaag
     5761 ctggcgcagg ttgttcccga tatctgtccg cgtgagaaag agtttgcggg tatgatgaaa
     5821 cagttacgtg acgacctggt ccgcgttgcg catggagacc tttccaaaca tacggccgtc
     5881 ctgttttgcg gctcgggtac gatcaatatc gatatctgcc tgaactctct tcttcctgcg
     5941 gataagaaag ttctggtggt caataacggt gcctacagca cccgtgcggt ggaagtctgc
     6001 gaatattacg gtcttcccca tatcgatttg aagttttccg tttacgaact tcccgacctg
     6061 tcggtaatcg aaaaggcgct ttccgacaat ccggacatcg ctttggtcta taccacgcac
     6121 catgaaacgg gtacgggtat cttgaacccc atccgtgaga tcggaaaaat agcccattcg
     6181 cacggtgccg tttttgttgt cgacaccact tcctccctgg gtatgattcc ttttgatatc
     6241 ggaaaggata atgttgactt ttgtatggct tcggctcaga aaggccttca ggccatgacg
     6301 ggtctttcct ttatcatagg tgatgaatcc ctgatacgtg cttcaaggga ttatccgaaa
     6361 cgctcctact attgtaacct ctatttacaa tacgattact ttgagaagac gggtgagatg
     6421 cattttactc ctcctgttca aaccgtttac gcagcccgtc aggctcttga tgaatatttt
     6481 gcagtaggtg aagaggctaa attcgcccgt cacaagaggg tctttgaagc catccataaa
     6541 ggtttgcaag agcttggtct tcagtatgcg atcaaacgtg aatggcagtc gggtcttgtt
     6601 gtttctgtat tgtatcctga tgatcccctc tgggattttg ataaggttca tgattactgc
     6661 tatgaacgtg gctttacgat ctacccgggt aagatttcca caacgaatac attccggctt
     6721 tgtgcgttgg gagagattga tgtggaggat attgagaggt tctttgaggt gatgaaaagc
     6781 gtaaatacgg tattagttaa taaataattt agctcattca tgttgaaaaa aaggttggac
     6841 tattcccaat taaaggttat acagttgaat atattaaaag atgtagatgc tttttgtcgt
     6901 gaaaataata taacttatta tttaacttat gggactttgt tgggggctgt aagacatcaa
     6961 ggatatattc cttgggatga cgatattgat attgctatgc cgaggaaaga ttatgaaaag
     7021 tttttatcaa attataatct aaatggaagt aaaaaaaatg tgtatcaagt tgttgctata
     7081 gagttaaata atgcttatcc ttatcctttt ggaaaggttc aagatttatc aactgtttta
     7141 ttagaatatt cagatattaa ttatccgttg gggataaata ttgatatttt ccctattgat
     7201 ggattacctg tagaccttaa aaaatcagac aaacattttt tgaagataaa gtggttaatg
     7261 atgataatga atcttaaaaa agtaaaaatc acaataaaac gttctttttt gaagaactta
     7321 atattattaa tagggaagat tttgacactt ttgattccat atcgatttat agtgtgcaaa
     7381 atgtcttata ttgcacagag gtatgattat gagaaatctg attatgtttc taacttgtct
     7441 tgtccagatg ggaaacatga acggacgtct aaaagagttt ttgaaaatag tatagagatt
     7501 ttatttgaag gtaataattt ctatgctcct ataggatatc atgaatggct tcataatatt
     7561 tatggagatt atatgaaaat gcctccagtt ccggaaagag tatctcatca taaatttgaa
     7621 atttataaga tactgtaatc atgtgttcta aggataattt tcttcaagaa gttcgtgcat
     7681 tatgtatatt tactgtaata ttgttacatg taccatttca gggacatgat aatataagtt
     7741 ttaatacttg gctaatgtca aagcagttga ttactttccc tgttgctgtg ttcttctttt
     7801 tatctggata tttttattct tttagaaatt ataagagtag aattgttaaa ttgctttgtc
     7861 cttttttatt ttggaatatg agtgtacatc taattaagtt tattagaggg gaaagcggat
     7921 ttaatattga aaatttttta ttaggtaatg gattacctta ttattattta gcagtacttc
     7981 ttcagattgt gttatttcat tacataatct ttaaatattg gagcgaaatg gtatatagag
     8041 tattgtccat aagtattagt attataagtt tgatggccta ttattatttt tccatttctt
     8101 attctatcca ttttaattgt tatctctatt ttcccttttg gatattattc tatactttag
     8161 gaacatttgg gaaaaaatat tggcgtaatt taatatctaa aatacctttt tgtgtaattc
     8221 tattgtttat tttaatatct gtctttttga tgttttttga agctaattta atgtattata
     8281 ttttgtttca agagggaatt gccggctctc aggttaagtt ctcttcctgg gtgtattcta
     8341 tactaattgt gttgctttta cttaaaatag attattcaat agacgaaaat gttactcgaa
     8401 attttggtac acttataggt gactattcat atggagtcta tttaattcat atatttatat
     8461 tatctttaat ttataaatta tgtattgtcg tttttaatga taattataat gtattattgc
     8521 cttttatcgc agcttctata acattggtta tttcagtttt tatgatttat attttaaata
     8581 aatgtcttcc tccctttata cttaaatttt taggattgta tgttaaaagt aactgatgaa
     8641 tgtacggctt gtggagcttg cttgtctata tgtccaaaga actgtatttc ttttaaaagt
     8701 aatgaagaag gttttttata tccacatatt gatatagaaa aatgtgtaga ttgcgatttg
     8761 tgttctaaag tttgtttttt aaatgatcat attactccga cttttaggga aaatgatatc
     8821 agttattatg cggctaaggc tattgaacga tgtaatttga gctcttctgg aggaatattc
     8881 ccattgcttg cagaatcagt tttgaagaat gacggcgtag taataggagc tgcttgggac
     8941 gataaattta atgtcaaaca tattcttatt aaatcaaaaa gtgaactgcc attattatgt
     9001 ggttcaaaat acatacagag taatacagaa aaggtcttca agatagttaa agaacatctg
     9061 tctattcaaa ctgttctttt ctcaggaaca ccttgtcaag tgaaaggact taaaacattt
     9121 ttgggaaaag attatgataa tttgattacg gtcgaattgg tttgtcatgg agttccttca
     9181 ccattggttt ttagacggta tttgaatggg gttttgaaat ataataattt agatatttca
     9241 cagtgtagta aaattaattt tagggaagta aaagatgata tctatagatt tgtgatatat
     9301 aataagacca aaataccatt ttatgaacaa tatacaaatc tttatactaa aacatttctt
     9361 caaaatttat tcttacgtaa ttcttgttat aactgtaaat gtaaattgga aaattccgta
     9421 ggagatttta tcttaggaga cttttgggga tgtagggatt tctatcctga attttatgat
     9481 ccaaaaggag ttagcttagt tattgtttgt actgaacgtg caaaaaaaat atggttaaat
     9541 ttaaaattat caagaataga agttaagaaa aagattgttt ttagaagtaa taggcattta
     9601 ttaaaatctg catcttataa tagaaataga gacttgttct ttaaaacttt tattcatgag
     9661 gctgagatat cactagatga tattttgatg ggatacacaa ataaggatat ttgggttaag
     9721 gttaaaggtt tgataattag tgttttacgt tttgtggggc ttttccaatt agttcaattg
     9781 tatagaaaat gaaaatagca ttacttactt taccatttgt taataattat ggaggaatat
     9841 tacaagctta tgctttaaaa cattttttag agttaagagg gcatagtgtt tgcattatag
     9901 atagaaattc aaattttaaa ataagtttta ttgatatatt acgtcttgca aaaaggaagt
     9961 ttctgggaaa tagaattcgt aactttgctt attttaagaa gcaatattta ttaccaatga
    10021 catctgagat tataactaat aaagaaatgt tattgcttga tgaaaaatat caatttgata
    10081 tttatattgt tggtagtgac caggtttgga gagcaatata ttatagagat attaaatata
    10141 atttttattt ggattttgtg tcgagtaaga ggaagatatc ctttgccgct tcttttggca
    10201 tatcttcttg ggaatataca aacactgaaa ctgatattat tgcaaaactg ttaatggatt
    10261 tttcttttgt ttctgttaga gaagatacag cagtaaggtt atgttctgat tacttgaata
    10321 ttaatgctgt gcaattccta gatccaactt tcttattgga taaaaacgaa tattgttgtc
    10381 ttgctgattg tttttatagt tctaaaaaga ttgatatttt tgcttatata atggggcctg
    10441 attcatctaa agataaatta attaaaataa taagcgatta ttctggcttg agtgttcaat
    10501 ctataactca aagtaaattc tcttttaaaa agaatgaaag tattcaagaa tggctacaaa
    10561 atttttataa gtcgaaattt gttgtaacag actcttttca tggtttagct ttttctttaa
    10621 tatttaataa accttttatt gtttgtggct ttagtaatag aggaatgggg agatatgaat
    10681 ctttattgag atatttctct ttggaaaata gacttttata ttcattggaa gatttaaaag
    10741 aactaaattt atctactatt tgggatataa attggaagga agttaatgct aaaattgctg
    10801 agaataaaag gtttgtattg gagttaatgc agacggtagg tgtataatgt cacttaaaga
    10861 aaatacaatt tatggtgtac tgtggagttc atttgagaaa tttggaactt tatcgataca
    10921 atttatttac atgattgtga tggcaagatt gctatctcct tctgattttg gtatagttgg
    10981 catgttgaca atttttattt ctgtaggcca agttatactt gatagtggtt ttggacaggc
    11041 tttaataaga ttacaaaaat atgatgattt acatttttct tcaattttta taattaatgt
    11101 tattatggga gttctactct atggaatatt attttatatg gctccatata tttctttatt
    11161 ctatagagaa cctagcttaa cattaatttc aagaatatct tttttgattt ttcccatcaa
    11221 ttcactaagt atagtccaat atactttatt agtgaaaaaa atggatttta aatctatttc
    11281 taaaatatct ttattctcga taattttatc tacaatttca ggtattacat atgggtattt
    11341 ttaccctaat atatttgcac tattaattca aaatgtctca ttttattttt ataggctact
    11401 tttattatgg tattatggaa actggaaatt atcatgtcga atttcatgga gtaaattaca
    11461 agatttgatg ccattctctt ttacgttatt agctacaggc tttatttcta ctgtcgtagg
    11521 agagttgtat tcattgtcta ttggtaagtt cttttcttca tctgttttag gtttatattc
    11581 tcaagcagaa aggttttcga aaattccatc tttttctata acagatgttg ttcaacgtgt
    11641 gacttatcct gcattatcag tgttacaaga cgatgatcaa aaattaaagc attcatatag
    11701 aatggttatt atgtgcacat tctttatagt attgcctgta atgctttttc tttttattag
    11761 cgctggcgaa atttttgaat tattatttac tgaaaaatgg gaacagg
//
