LOCUS       c00374_gnlPro..        12597 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BJNGDNFJ_374.
ACCESSION   c00374_gnlPro..
VERSION     c00374_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:38:27
            Original ID  :: gnl|Prokka|BJNGDNFJ_374
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3753
            Orig. end    :: 16350
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12597
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13753:16349]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12596
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12597
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12597
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2295..2999)
                     /locus_tag="ctg374_3"
                     /transl_table=11
                     /translation="MKKLRMTLAASMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGKNDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
     CDS             3181..3729
                     /locus_tag="ctg374_4"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYECYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             3742..5058
                     /locus_tag="ctg374_5"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAVR
                     TNSIEPAYRAHGNASAPNREASRPLVAQHIRISVGDEQQEEMLPVETTDEAVGIGQQAE
                     EPVVEDTDHETTMQAEEPERTREDRYRPSGRDKLHLPEKNSSGRDTKGWAVGLSVGNTG
                     GFSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREK
                     KIADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIP
                     VRANWNFVDTKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRV
                     GLYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             5235..7697
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 78; E-value: 1.5e-24)"
                     /gene_kind="other"
                     /locus_tag="ctg374_6"
                     /sec_met_domain="Fn3-like (E-value: 2.1e-25, bitscore:
                     78.0, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 5.2e-57, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.6e-51,
                     bitscore: 164.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQAEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SLLYKDMSQQIYTDDSFTQNGFKSEYYNTRNLTGELFQAAIEPAIDYAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLTSSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVTVVVNAGGGIDFRNWGQNVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYDNYYDNRNVPHKRVQYAEGVFVGYRGYERNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGNRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRIRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             7728..9932
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 87; E-value: 2.2e-27)"
                     /gene_kind="other"
                     /locus_tag="ctg374_7"
                     /sec_met_domain="Fn3-like (E-value: 3.2e-28, bitscore:
                     87.0, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 3e-75, bitscore:
                     242.7, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 6e-53, bitscore:
                     169.1, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGFGNSFTSAQTTEKEKFISGLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRMGSMLDVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKAGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAADKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRSKVVTLYDALVRKGLEVNYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALQQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKDAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNAGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.7;
                     E-value: 2.9e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg374_8"
                     /sec_met_domain="Radical_SAM (E-value: 3.1e-30, bitscore:
                     95.0, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILHMAVSQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKVNGIHICLDSNG
                     SIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHERPFWLRYV
                     LVPGYSDSEEDIRLLGENLGKYRQIQRVEILPYHRLGVHKYEVMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(10728..12596)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg374_9"
                     /sec_met_domain="Gly_radical (E-value: 3.8e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 7e-301, bitscore:
                     987.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPDNY
                     ARGRIIGDYRRLALYGIDRLVEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIKVM
                     GEYYGLDLSRPATSAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIFIEYDLAHGK
                     IDETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKTSF
                     RFLQTLYNLGPSPEPNMTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNCDD
                     YGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGNTLKF
                     EEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGLSI
                     AIDSLSAIKYAKVTARRNDIGLTEGFDMEGSFPCFGNNDDRVDHLGVDLVYYFSEELKK
                     LPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIASLS
                     SVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLNRE
                     MLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
ORIGIN
        1 tcggtggaag ccaatattcc ggagaatccc acaatggcat tgagcggcgt acggatttca
       61 tggctcatgt tggcgaggaa tgcggatttc agtttattcg actcttccgc acggttcttg
      121 gcggaaacca gttccgtctc catctttttc cgttcggtga taaccagcga agagcccacc
      181 agggtcagcg gcttattgtt ctcgtcgtag gtttctacgg cggcctgggc ctccacccag
      241 tcgaagtgtt tgtgtctgtc ggcatgattg atgacgcggt attcctcctt gactttctgg
      301 atacgtccct caatcaggtc tgtataggct tgtttcactt tttccaggtc ttccttgtgt
      361 attttggaga aatactggct gtcgggtacg gacagctgtt catcgtccat gataccggca
      421 ttattgctga gctctatcgg cttgttgaca tcgcagagta tggtgtgtgt ccggaggttc
      481 catttccatg gtacgatgtt ggcaacgtcg agtgccatgg aaagtttccg gtttgtcgaa
      541 ctcaactgta tttgagtgtg gtgcaactcg gtgctgtcaa cgcagaagac gtgcatgtat
      601 tcgccattgt cgcttgcctt gactacaatg tcgtagaaag tgtctatctt cttgtaataa
      661 taggggaaag ttacggaacg tttctccttc aatgcaatat tcatgaaatg gaggaactcg
      721 ttcatggatt cgggaaatag ttcgcttccc cgcttgccga cagcctcttt gcgcatgata
      781 aatctgtctt cgaagaattt gttgacatct atatataagg tgtcagtaat gcgccctttt
      841 tcatctttta taagtttctc atacatgtat aggatgggca tgttgtttat cagatttcgg
      901 tatttgagat tgctgtccag ttgttgctgt tgtaatcttt tgattctact cagtgactgt
      961 aggcggagat attggaaaaa gaacagcaga gttatgattg cggcagtgat actgataatg
     1021 acatattcgt acttctccca gaaggtggga ggcatgttgt agaatatggt acccttgggg
     1081 catagcttcg gattcaggtc acgctgcaga agagacttat agttgaatac gggggatccg
     1141 tcgtcgggat agtagaacgg gatgttgcgt gccggggtac cgttcaatat cttgtggatg
     1201 gtttccagta gccgggcatt ataattctct ttgttgtaaa tgtatccgcc tacaatcccc
     1261 ccttcttctt caataccgat ggcccttagc gaaaacaaag ggatgggggc ggtagagatg
     1321 acccggtggg agttactcct catgatattg tcatggggag agctcttgta cagccaggat
     1381 gaaaagatga ctccggtagt atggggactc acgtggttca gtatattgaa aaggctgtcc
     1441 gtccggatgt ccttcgcact caagaactgg taatccaact ccggatactt ttcacggata
     1501 atctcggaca agtcatagtc gttctgctgg cagatgtatg tttcatcccc tatatacatg
     1561 accttatcca tttgggggat gagttgcttc atgagttgca ggttctcgtt caggtataca
     1621 ctggattgca ttaaggtcag attgtacttc ttctgtaggt cactgatggg aatacgctct
     1681 gtgcggggca gggcgtgctc gcgtatcatt gtttccttag gaccggtata atccctctca
     1741 ccacataata tcatggggat atcgggccac tgccggttca gttcatcgca catgatgaaa
     1801 cttccgcatc cgataagcac gataagttta gggttcttgt aactcttgaa caagctctct
     1861 ttgaatgtct ccagtttatt ttcctcgtca agtgtcagca ttttcatgtg tgcggtgtat
     1921 actccgatgt ggctgttctg tgatgccatg ttcacaatgg aggtgatgaa atcattactc
     1981 cagggattgg cttctgtata agtgttgatt atcagaatat cgtcgacgtc tgttgcggga
     2041 gattttccat atagggtgtc tgtgcaggtg aacgagcaga gtattgcaat tactgctccc
     2101 agtatgtatt tcatatcctt tggaccgttt taatgtttgc tattgtgaaa attcttacaa
     2161 atgtaggggt ttcccggtgg atagacaaag aaaaagatga atttaagcgg gatatggaaa
     2221 aataaagcgg agcaacatat tgcaatgtca ctccgcttct cattgagatg ttgaaagatg
     2281 tgttttcagg agatttagtt gttttctttt ttaatgtcta tggtcatgaa ccgttcaccg
     2341 tcatatagac ttttgacacg gatgttcagt ccttttttct ctttcagctg ttccgctata
     2401 ttgtccagct tgaaggaggc cagtccggtg cccagcgtga gctggctgtc attgtaggca
     2461 ttgtggcgga attcgagatt gacgtaatcc ggtttgtcgt ttttgccggt ggatgcttca
     2521 ttgatgacca ggttcagcat gtgcttcttg tcttcgttgt tgctgtggta gaattgatat
     2581 ttgatgttca gatactcgcc cgtaatccat aaatccgtgg cgttgatgtt gtcgtctccg
     2641 atactgtccg ccttttcggc aggcatggag tagatgtctt tggtcagaat gttttcgatg
     2701 tgctttattt gggcattgta ttcgtagcct ggaagtttct cttccagttc gcggaagtag
     2761 atgaaagccc tctggccgtc tattacggca tagtcgtgaa cataggttgt gtcactggga
     2821 tatagtttac tgccttcgtc cagtgagaaa tagtagtctt ttccttcgat gacctttacc
     2881 gtacctacgg cgaacaaagt gtcatatttg tcatcccaat cgtccaggca tgattgcaat
     2941 acaatggcag tcaggaataa aagcatggat gctgccaatg tcattctcag tttcttcata
     3001 agtggtaggt tttagctctt tttctgttta aaacttattt ttgtattcag aaaatgcggt
     3061 gaaaagctaa atactgcgta gtatactgtt aaagaaatga aagtatgatt ttcttctctg
     3121 cctgatgcag tatttttgcg ccgattgcat ttatagggta aacacgtgtt aaaagagaga
     3181 atggaagaac aggaattggc agaacgctgt aggcaaggag acaatcttgc ccgcaaagaa
     3241 ctgtatgagt gctatgcggg acgcatgctc agcgtatgcc tccgttatgc aggtgaccgg
     3301 gagactgccc aagacttgat gcatgacggt tttctgaagc tttttgattc tttcgataag
     3361 ttcacttggc ggggagaggg ttctctgcgg gcatggatgg aacgcgtaat ggtgaatacg
     3421 gtgttgcagt atttgcggaa aaatgatgtg atgaatcagt catcggcctt ggagaatgca
     3481 cccgaagctt atgaggaacc ggaaggttcg tcaatagatg tcattcctca aaaagtactg
     3541 atgcagttta tcagtgaatt gcctgccggc tatcgtaccg tattcaactt atatattttt
     3601 gaagagaaat cccataagga gattgctcga ctattgggaa ttaatgaaaa atcctctgcc
     3661 tcgcagttga cgcgtgctaa agcgacttta gcggcaaaag tacgtgagtg gatgaaaaga
     3721 aatgattaaa tgaaggaacg tatggaagat gaattgtggt tgaaaaagat aaaggacaag
     3781 ctggaagact attccgaacc gctgccggtt gccggatggg agcggttgga gaaggaattg
     3841 tccgtttccg gagctccgat aaccggaccg cataggatga tacctttccg tcgctgggcg
     3901 gtggccgcgg cagctgtgtt gctggtggcg gtttcgtccg tcagtctgtg gctgttgcag
     3961 agtccggtag ggaatgaaat gcggcatacg tcagtgcctg ctttggctgt ggctccggac
     4021 gtcttgccgg aacagacggt acctgccgta cggactaatt ccatagagcc tgcctatcgg
     4081 gcacatggaa atgcatcggc acccaatagg gaggcaagtc gccctttggt tgcacaacat
     4141 atcagaatat cggttggcga tgaacagcag gaggaaatgt tgccggttga aactacagat
     4201 gaggctgtcg gtattgggca gcaggcggaa gaaccggtag tggaagatac agaccatgaa
     4261 actacaatgc aggcagagga accggagaga acaagggaag accgctatcg tccgtcaggc
     4321 cgggacaaac tgcatcttcc ggaaaaaaac agttctggta gggatactaa aggatgggcg
     4381 gttggcttgt ccgtaggaaa tacgggaggt ttttcattgg cgaatgaagg ggaagcgaat
     4441 gtgatgtcgg actacatgcc tggaagtcct atttatggcg gtaacgtaga tttatcctct
     4501 acggccaatg gcattgttac tattcccgac gggcaggaac tggtttttaa ggatggtatg
     4561 ccctatctgc aaagacgcga aaagaaaatt gcggatatag accataaaca accgctcagt
     4621 ttcggtgttt cggtgcggaa aaacttggcg aagggtttct ctgtggaaag cgggctgacg
     4681 tatacctatc ttgcttctga cgtaaggtat gagggcagct cggaaaagat aagccagaag
     4741 ctgcattata ttggcattcc ggtacgggcc aactggaact ttgtggatac aaagaacttt
     4801 acgatgtatg tttcggcggg gggtgccatt gaaaaatgtg tgtatggcaa gattggtact
     4861 gagagtgaga ctgtgaaacc ggtacagctt tctgtcatgg gtgctgtcgg tgcccagtat
     4921 aacataagca atagggttgg cttgtatgtg gaaccgggag tatcctattt ctttgatgac
     4981 ggttcgtcga tacagactat acgcaaggag aacccgtgta actttacgtt gcaggccggc
     5041 atacgtctta cttattgatg gcaggacaga catgtttttg tccactttct tgtagattca
     5101 gaattttctt aataactttc ggccgtgttt cttcgttggt ggatgaaggg acacggtttt
     5161 ttattggttg agaagaaaga aagtaggtcg ggacatgccc ggcaatataa caaacacgta
     5221 gtaaaataga caaaatgaag attaaaaaga aagtagcctt aagcgggcta ttgctttgtt
     5281 gtgcaatcac ggcaaaagca caagtgtgta ttactcccca ggcggagcag cgtgccaggg
     5341 agttggtttc tcaaatgact ctggaagaaa aaatcgatta catttccggt cccaaatctt
     5401 tttatatccg ggctgtgccc cggcttggca tacccgaaat caggatggcc gatggtccgc
     5461 aaggcatacg taacaatact caaagtaccc tgtatccttg tggtatcttg tcggcttcga
     5521 catggaaccg taagttggct agagaactgg gacatggttt ggcccgggat gcaaaggccc
     5581 gtggggtaag tattctgttg gggcccggag tcaatatcta ccgttctcct ctatgcgggc
     5641 gaaactatga gtattttggt gaagaccctt atctgacggg cgaaacagcc aaagaatata
     5701 ttctgggagt gcaggaagag ggagtcatgg ctacggtgaa gcattttgca gccaataacc
     5761 aggagtggag caggcatcat gccagctcgg atgtggatga acgcacgttg caggaaattt
     5821 attttcccgc gttccgaaaa gctgtgcagg aagcaggagt aggagcggtc atggatagct
     5881 ataatccgct gaacggggtg catgccaccg aaaacagctg gctgaacatt gatgtactgc
     5941 gcaagcagtg gggatttaaa ggtatcctga tgtctgactg gacatctgta tattccggtg
     6001 tgggagccgc taatggaggg ttggatttgg aaatgcccgt cggtaaattc atgaccaggg
     6061 agattcttat tccggcaata gagaatggta tcgtgaagga agagaccatt gacgccaaag
     6121 tccggcatat actccagaca ttgattgctt ttggagcact tgatactccg agagaagata
     6181 aatctatcga taaagacaat gcacagtcta aggaaattgc acttgacttg gcgagggaag
     6241 gagtagtgtt attgaaaaat gataacggta cgttgcctta ccggaacggt agaacattgg
     6301 taatcgggcc taatgccgat attattccca caggaggggg aagcggattt gtcacccctt
     6361 attcggtagt gtcgctctat gacggtatgg ttcagttgaa gggcggcaga cagatagaac
     6421 tgctgtctga cagccttctt tataaggata tgtcccaaca gatttatacg gatgacagtt
     6481 ttacgcaaaa cggttttaag agcgaatatt ataatactcg taatcttacc ggagaactct
     6541 ttcaagctgc tatagagcct gccatagact atgcctggaa atacggtgca ccgttcgacg
     6601 gcatgccggt agatcagttt tctgcccgtt ggacgggagt ttacaaggct gacaaggatg
     6661 gaactgtcaa gttccagctg gctggcgatg acggataccg tctgtttgta aacgataagc
     6721 tgattaccgg agattggggg aaccattcat ttagtacccg cagtgcattt atgcaggtca
     6781 gtgcagggga gatataccgg ctgcgtattg aatattttga taatgtgggt gaggcgactg
     6841 tcagtttcca ggcaggaatg atggatgagg agcgtttgac ctcttcactg aagcatgcca
     6901 ggaatgttat tgtatgtgcc gggttcaaca gcagtacaga aggtgaaggg ttcgaccgtc
     6961 cgtttgcatt gtcatacggg caggaatatc tcattaataa agtggcttca cttcatgata
     7021 atgtgactgt ggtggtgaat gccggaggtg gaatagattt ccgcaattgg gggcagaatg
     7081 tacaagctat tttgatggca tggtatccgg ggcaggaagg cggaaaggcc cttgccgaaa
     7141 tcattacggg caagctttcg ccaagtggca aactaccggt cagcatcgag gaaaaatggg
     7201 aagataatcc ggtatatgat aattattatg acaatcgcaa tgtacctcat aaacgggtgc
     7261 agtatgccga aggcgttttc gtaggttata ggggatatga acggaacgga aagcagccac
     7321 tctatccttt tgggtatgga ttgtcataca gtagttttga atacagtaat ctgagtgttg
     7381 agaagacggg tggaaaccgg gttacggtaa gctttgacat caagaatacc ggaaagatgg
     7441 atgctgcaga agcggctcag gtatatgtgc gggatgtgga atgttctgtt ccgcgtccat
     7501 tgaaggagtt gaaaggctac gataaggttt acttgaagaa gggggaaacc aagcgcatcc
     7561 ggatattgct ggatgaggaa gcctttgcct actatgatgt ggaatcacat cggtttgtag
     7621 tggaaaaggg gacttttgag attctggcag gtccttcttc ggctgatttg ccgttgaagg
     7681 caactgttgt tttatgataa aataaatatc aaaacaagaa tggcggtatg aaaaagataa
     7741 taatactgat ggtttgtctg tggggatttg gtaacagctt tacttcagca cagactacgg
     7801 agaaggagaa atttatctcc ggtttgatga aacagatgac gctggacgaa aagataggcc
     7861 agcttgcaca atgcacctac cgggggaatt ttaccggacc cgacggtgga aatattccta
     7921 aggaagaata cgtacggcag ggcagaatgg gctctatgct ggatgtgata ggagtaaagg
     7981 acatacgccg ttatcaagaa cttgctctgc agtcgcgttt gcgcattcct ttaatttttg
     8041 gactggatgt tatccacggc tatcgtaccg ggtttccgct tcctcttgcc gaggctgcaa
     8101 gttttgattt ggccatgatt gaggaagctg cacgctacaa tgctttggaa agtgccgccg
     8161 atggtttgaa ctgggttttt gccccgatgg tggatatttc gtgggacgca cgttggggac
     8221 gcgtcatgga aggggccggt gaggaccctt attatggttc tcgggtagcg gaggcgcgtg
     8281 tcagaggctt gcaaggagac gatttggcgg acacgacgac tgtcatggca tgtatgaaac
     8341 attttgccgg atatggtgca ccgatagcag gaaaggagta taatagtgtg gatatgtcaa
     8401 tgggccactt tgccaatttt tatatgcctc cctataaggc ggccataaag gcaggagcag
     8461 ctaccgtgat gagtgctttc aatgatttta ataatattcc ttgtactgcc aatgatttct
     8521 tgctcaaccg gctattgaga gagcagtggg gatttaaggg atttgttgtg tccgattata
     8581 attcggtaga ggaattggtg aaccaccgtt atgctgctga caagaaagat gccgcagcca
     8641 aagcgctgaa tgctggtctg gacatggaga tggtaagtac ctgctacttg acttatctga
     8701 aggagcttgt tcaagaaggg aaagtaaagg agagtgtgct tgatgatgca gtacggcgta
     8761 ttttggagaa gaaatatgag ttgggattgt ttgaggaccc ttttcgctac tgtaatccgg
     8821 aaagagcagc cagaatactc aatgcacccg aagtccgcaa tgcttcgctc cgtatggccg
     8881 agcgttccgt tgtattgctg gagaataggg aatccgtact tccgttgacg gcgcagacga
     8941 ggaagatagc cttgatagga ggactctcaa aatcccaata cgatatggca ggcgcttggg
     9001 ccgccactac ggaccggagc aaagtggtga ccttgtatga tgcactggtc cggaaaggac
     9061 tggaggtgaa ctatgctgaa ggctatgata tgaagagcaa tcaattgacc ggactgcagg
     9121 aagcattgca ggctgctgag gcttcggatg tcattgttgt ggcggtaggc gagagattcg
     9181 gtcagagtgg cgagaaggct tccaaagtga atatagctat acccgagggg cagcagaagc
     9241 tggtgtcgga actggcaaag actggaaaac ctgtcattgc tcttgtcatg tgtgggcgtc
     9301 cggtaatctt caatgagata agggaacatg ctgatgcggt actgtgtact tggtggctgg
     9361 ggagtgaggc cggcaatgcc atatgcaatg tgttgtgggg agagtataat ccttcggcta
     9421 aattgcccat gacatttcct gcacacgtag ggcagattcc catttattac cagaataaga
     9481 gtaccggtcg tcctaccgca ttgcaacaga cttataaggc atcctatatc gatgcttcca
     9541 ctgagcctgc ctatcctttc ggatatgggc tttcgtatac ggattttgga tattctgatt
     9601 tgaaactgct gccgggcaag gatgcaggcg tccatacgga ggtgtcggta aaagtgacta
     9661 ataccggtaa gtgtgcagga gaggaagtag tccagttgta tgtgcaggat aaggtagcgt
     9721 ctgttacgcg cccgataaag gagttgaagg gcttcaggaa aattcatctg aatgcgggtg
     9781 aaagcaaaac tgtagctttt cagataactg acgatgcact gggattctat gacaatgaga
     9841 tgaattatat ggtagaacct ggtgatttcg tctttatggt gggtggcagt agtgatgatg
     9901 tacagcagat tacctataac ttgaaagaat aggattcttg tcctataaat gaaaagcaag
     9961 gctgtctgga atcatatccg gacagccttg cttttctgtt ttagttggtt atcacattcg
    10021 tgaaatactc tttgaacagt ttttctgccc gttccagttg ttccggagta ttttccttca
    10081 cttctttcaa tttgtaatcc catcccatga cttcgtattt gtgaacgccc agacggtggt
    10141 aaggaagtat ttccacccgt tgtatctgcc ggtatttgcc gagattttca cccagtaggc
    10201 ggatgtcttc ttccgaatcg ctgtaaccgg gaaccagtac ataacgcagc cagaaggggc
    10261 gctcatgttc ttcgagccag gcagcggtgc ggagtgtctg ttcgttgctc cgtcccgtca
    10321 gcgtgcggtg gcgttcggga ttgaattgct tgatgtccag cagcacgagg tcagtcaggc
    10381 taaagagctc ttccaccttt tcattccaga tgcttccgtt actatccagg cagatatgga
    10441 tgccgttcac cttcagttcc ttgaataggg gaatcagcgc ttctgcctgc agggtaggct
    10501 cgccgccgga gaaagtaata cctccttttt tcccgaagaa tgctttttgg ctgacagcca
    10561 tgtgcaggat ttcttctggg gtggtgggag tgcctccttt tacatcaatc gtatccggat
    10621 tggcacaata cagacaacgg aacggacatc cttgcaggaa aacaacgagc cggagacccg
    10681 gcccgtcgaa tgttcccata ctttcgtagg agtgtatgtt tatcatatta catcctttcg
    10741 tggaatgaac ggctgatgac ttccaactga tgctcgcggc tcaacttcac gaagttcact
    10801 gcatagccgg aaacgcggat ggtgagttgc ggatactttt cgggatgttc catggcatct
    10861 tccagcattt cgcggttcag tacgtttacg ttcaagtggt gggcaccttt ggtgaagtag
    10921 ccgtccatca tggttaccag gttctctaca cgttcttccg gtgtcgggcc cagtgatttg
    10981 gggacgatgg agaacgtatt gctgatacca tcctgcgagt cgcggtaacg caatttggct
    11041 acagagctca aggaggcgat ggcaccgttc ttgtcacgtc cgtgcatcgg attggcaccc
    11101 ggagcaaagg caacaccttt ggcgcgtccg tccggagtag cgcctgtctt tttgccatac
    11161 atcacgttgg atgtgatggt cagcaatgaa agagtggggc gggcattttt gtagacgggc
    11221 agtttcttca gttcttcact gaagtagtat actaaatcca caccgaggtg gtctacacgg
    11281 tcatcgttat taccaaagca agggaaagaa ccttccatat caaaaccctc tgtcagacca
    11341 atgtcattac ggcgggcagt gactttggca tatttgatgg cagagaggga atcgatggcg
    11401 atggaaagtc ctgccacacc gtaagccaga ttgatgcgcg ggtcggtatc gatgaatgcc
    11461 atctgagcct tttcgtaata atacttatcg tgcatgtagt ggataatgtt catggcttcg
    11521 ttgtatacgc gggcaatttc agtcagtacc ttcttgtagt tggccattac ttcctcgaat
    11581 ttcagcgtgt tgccggtcag tacgggaata cctttcacca tgacggttcc ggtattttcg
    11641 caacgtccgc cgttgatggc gagcagcaat gccttggcta ggttggcacg tgcaccgaag
    11701 aactggattt gctttccgat ggcttggtaa gatacgcagc aggcaatacc gtaatcgtca
    11761 cagttgcgta cttcgcgcat caggttatcg ttctcgtatt ggatagagct tgtgtctacg
    11821 gaaactttgg cacagaaatc cttgaaacct tccggcagtt ccgggctcca cagtaccgtc
    11881 atgtttggtt cgggagaagg accgagattg tatagggttt gcagaaaacg gaaagaggtt
    11941 ttggtcactt tcacacgtcc gtcgttgaaa cggccgccaa tggcttcggt cacccaagtc
    12001 gggtctccgg caaagatgtc attgtacgac tgcatacgca gatggcgtac catgcgcagc
    12061 ttgatgacga actggtctat cagttcttgt gcaaaagttt cgtcaatctt gccgtgagcc
    12121 aaatcatact cgatgaagat gtcgaggaat gaagatacat tgcccaatga catggcagca
    12181 ccgtcttgtt ctttcacggc agccagataa gccatatata cccattgcac agcttcttgc
    12241 gctgatgttg cggggcggct gaggtcgagt ccgtagtatt cgcccatcac tttgatgtct
    12301 ttcagagcct tgatttgctc tgctacttct tcacgcagac ggatacgggc ttcggtcatg
    12361 ggacctgtca gattgcgcaa gtcttcttgc ttggcttcga caagtcggtc gatgccgtag
    12421 agtgccagac gacggtagtc accgatgata cgtccgcgag catagttgtc gggaagaccg
    12481 gtcaggaatc ccaatgaacg gaaggaacgg atttcttcgg tatatacatc gaatacgccg
    12541 tcgttatgtg ttttgcggta atgggtgaag atgtctttta ctttatcgtc cacttcc
//
