LOCUS       gnlProkkaOIKMCNEA_631   9502 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIKMCNEA_631.
ACCESSION   gnlProkkaOIKMCNEA_631
VERSION     gnlProkkaOIKMCNEA_631
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:40:38
            Original ID  :: gnl|Prokka|OIKMCNEA_631
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9502
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..639
                     /locus_tag="ctg631_1"
                     /transl_table=11
                     /translation="MQKKKINPRDFLTEEILMAGSTAKMAELVAKEIYNIRESKNALVR
                     GQADNMPKDGEQLKIMLANLEEQEAAMTEMFSGTLNKDEKIFNIRLTPDKEMDNEVAFR
                     FSKKLGIVANNDLAGEPVYITLKNLKTVNVPEDDGKKKVDGIAYNVPGKAQVTLTEGKK
                     QWFNGELPVTQFGTIEYLAPALFNKKSTVQVTFNPDTGGLIKVDREEGE"
     protocluster    1..9502
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[773:1127]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      774..1127
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..9502
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9502
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(774..1127)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg631_2"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 53.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.3e-10, bitscore:
                     29.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVKEKINLLDVIPFRSENITAEKGSDGTVTIAFPRFKYEWMRR
                     FLLPKGMSADIHVRLEDHGTAVWELIDGKRTVRRIIEELAEHFNYEENYESRITAYITQ
                     LQKDGFVKLVIEN"
     CDS             complement(1134..2522)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97.1; E-value: 1.4e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg631_3"
                     /transl_table=11
                     /translation="MTEQLKNKLSDSKTLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACILMVLGCGLKYY
                     AISTTFPEGALIMGFKTQVFLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPIADYFGYTDESGSFHTNIPMPILLCLIMLCIGTIAFFIYTF
                     YDKKLDASLDAQGEEPEEPFRMKDVMLIVTNKGFWLIALLCVLFYSAVFPFIKYATDLM
                     VQKYNVDPKLAGNIPGLLPIGTIFLTPLFGTLYDRIGKGATLMIIGAVMLIGVHTLFAL
                     PILNVWWFATVIMIVLGIAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFACFGVLALIVALMLKAEDKKKGYGLQEA
                     NIKK"
     CDS             complement(2693..3073)
                     /locus_tag="ctg631_4"
                     /transl_table=11
                     /translation="MYLLLVILMVIAAILMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWGLAAFMVVMSIATAYVVPTSSSKTQDVIMEQAQQEEQTNPYNLPVGTTA
                     PKTDAAAPVEAPATETPATPAN"
     CDS             complement(3078..3833)
                     /locus_tag="ctg631_5"
                     /transl_table=11
                     /translation="MISANLQQWIQHPETLNKDTLYELRTLVTRYPYFQSLRLLYLKNL
                     YLLHDISFGAELRKAILHVADRRKLFYLIEGERYILKPRKKNALPETEVLEEEPSLDRT
                     LSLIDAFLATVPEEVSAQTSLDYATDYTTYLLQEDDTPELEETPKLRGHELIDGFIERS
                     EEETSIRLQPADENKAISEEEESETHHEEDEDDSCFTETLAKIYVKQHRYSKALEIIKK
                     LSLKYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(3839..4339)
                     /locus_tag="ctg631_6"
                     /transl_table=11
                     /translation="MRISLLVFTLVVGISCTVSYKFNGGNINYDKVKTISIADFPIKSD
                     YVYAPLGTKFNEDLKDIFLRQTRLKLVNNNADLEIDGEITGYNQYNQAVSADGYSSETK
                     LTITVNVRFVNNTNHEQDFEQQFSAFRVYDSRELLTAVQDGLIAEMTKEITDQIFNATV
                     ANW"
     CDS             complement(4347..5573)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 389.6; E-value:
                     3.4e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg631_7"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNTEALTRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGEDVLLLFRKFASDFAEKYRMPAIQLTEDAKRV
                     LLSYSWPGNVRQLKNITEQISIIETNREINAPILQSYLPAQSTQRLPALFGVKTGKSFE
                     SEREILYQVLFDMRQDVTELKKLVHEIMSERGAVTSNVGTFYTPAPVVAPTPSVPAIIH
                     PVKPNCPDDDDIQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAKDLNISERTLY
                     RKIKEYGLE"
     CDS             complement(5598..6695)
                     /locus_tag="ctg631_8"
                     /transl_table=11
                     /translation="MEDNKIKIGITQGDINGVGYEVILKTFADPVMLELCTPVIYGSPK
                     VAAYHRKSLDLPTNFSIVNTAAEAAHNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     KAIEEFREGLIDVIVTAPINKHTIQSEGFAFPGHTEYIEQRLGNGSKSLMILMKEDFRV
                     ALVTGHIPVREIASSITKELIQEKLAIFNRSLKQDFGIGAPRIAVLALNPHAGDDGLLG
                     TEEQEIISPAIQEMAAKGILCYGPYPADGFMGSGNFTHFDGVLAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDTVDDDI"
     CDS             complement(6700..7746)
                     /locus_tag="ctg631_9"
                     /transl_table=11
                     /translation="MKKYLFYLSMALVAVVLFSCKSGKKSVFTPTSSGRAYEVLVVVEK
                     PVWERPAGRALYNVLDTDVPGLPQSERSFRIMSTSPKDFDAILKLVRNIIIVDIQDIYT
                     QPKFKYAKDVYASPQMILTIQAPDEASFEKFVEENKQPIIDFFTRAEMNRQISFLEKNH
                     NDYISTKVGSMFNSDIWLPAELSSSKTGEDFFWAGTNAATGDQNFVIYSYPYTDKDTFT
                     KEFFIHKRDSVMKANIPGAKEGMYMATDSSTVEVRPIDIHGDYTMEARGLWRIKGDFMG
                     GPFVSHTRLDKASHRIITTEVFIYSPDKMKRDLMRRLEASLYTLQLPTEKAQEQIPMGI
                     EQEEKTNK"
     CDS             complement(7821..8855)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg631_10"
                     /sec_met_domain="PF04055 (E-value: 8.3e-19, bitscore: 58.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKYPLLGMTLTELQSVTKDLGMPAFAAKQIASWLYDKKVTSIDE
                     MTNLSLKHRELLKGEYDLGISAPVDEMRSVDGTVKYLYQVSDNHFVEAVYIPDEDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTASLTANQILNQIAALPERDKLTNVVMMGMGEPLDNL
                     DEVLKALHILTASYGYGWSPKRITLSSVGLRKGLQRFIEESECHLAISLHSPFPSQRSE
                     LMPAERAFSIKEMVDLLKNYDFSKQRRLSFEYIVFKGVNDSLIYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGAGMEAMTSFRDYLTSHGLFTTIRASRGEDIFAACGMLSTAKQEE
                     SNKN"
     CDS             complement(9033..9500)
                     /locus_tag="ctg631_11"
                     /transl_table=11
                     /translation="MLVSVIEEGYRPLAQVQDQLRAEIIRDKKAEKIMADMKAANATTI
                     AQYTSMANAVSDSVKHVTFAAPAYVAALRSSEPLVGAYASVSDINKLSAPIKGNGGVFV
                     LQVYAKDKLNETFDAQSEEATLENMHARLASRFMNDLYLKGDVKDKRYLFF"
ORIGIN
        1 acacagaaaa agaagataaa tccacgtgat tttctgaccg aagagattct gatggcaggt
       61 tctacagcta aaatggcgga gttggttgcc aaagagattt ataacattcg tgaaagtaaa
      121 aatgccctgg tacgcggaca ggcagacaac atgcccaaag atggggagca actgaagatt
      181 atgctcgcca acctggaaga gcaagaggct gccatgaccg aaatgttctc gggtaccttg
      241 aataaagacg aaaagatatt caacatccgc ctcactccgg ataaggaaat ggacaacgaa
      301 gtagctttcc gcttttcgaa gaagctgggc atagttgcca ataacgatct tgcaggagag
      361 ccggtttata tcacgctgaa gaatctgaaa accgtcaacg taccggaaga cgatggcaaa
      421 aagaaggtgg acggcattgc ctataatgtg cccggcaaag cacaagtaac actaacggag
      481 gggaaaaagc aatggtttaa cggagaactt cctgtcacac aattcggtac tatcgaatat
      541 ctggctccgg cgcttttcaa taagaaatcg actgttcagg ttactttcaa cccggataca
      601 ggaggcttga tcaaggtaga tagagaagaa ggagaataaa acataatcaa aaactccggc
      661 cgatctaaaa atgaagtgca ccccaaaagt tcatgtttaa cttttagggt gcacttcatt
      721 tttaaatcag ccggagtctc tttattatat tccgatagta tatcgtaatg caatcagttc
      781 tcaatcacta atttcacaaa tccgtctttc tgcaactgag tgatataagc cgtaatacgt
      841 gattcgtaat tttcttcata attgaagtgt tctgccagct cttcaataat ccggcgtacg
      901 gttctctttc cgtcaatcaa ctcccatacg gcagtgccat gatcttccag ccggacatga
      961 atatccgcag acattccttt aggcaacaag aatcgccgca tccactcgta tttaaaccgg
     1021 gggaaagcaa tggtaacggt accatcgctt cccttttcgg ccgtaatatt ttcactacgg
     1081 aaaggaatta catccagaag atttattttc tctttcacgt ctgccatata ctgttatttt
     1141 ttgatatttg cttcctgcag tccgtatccc ttcttcttgt cttccgcttt caacattaaa
     1201 gctacaatca gagccaaaac accgaaacaa gcaaagatag ccataggcaa agtatagtca
     1261 taagtctgcg ctccatccac aacaggacct ttgcaatagg tattcaacac ccatccgatc
     1321 aacagaggta cccccatcaa tccccagttc tgcacccaga aaatcaaagc ataggcagta
     1381 cccagttgtt tctccggaat aattttcgga acagaaggcc acatggccga aggcaccagt
     1441 gaaaaagcaa tacccagaac aatcataatc acagtggcaa accaccatac gttcagaatg
     1501 ggaagcgcaa acaaagtatg cacaccaatc agcatgacgg caccgataat catcaacgtc
     1561 gctcccttac cgatacggtc ataaagagta ccaaacaacg gagtcaggaa gatggtacct
     1621 atcggtagta atcccggaat atttccggcc agcttagggt ctacgttata cttctgcacc
     1681 atcaagtcgg ttgcatattt aataaagggg aaaacagcag aatagaatag tacacacaat
     1741 aaagcaatca gccagaagcc tttattggtg acaatcagca taacgtcctt catacggaac
     1801 ggttcttccg gttcttctcc ctgagcatct aaagaagcgt caagtttctt atcataaaag
     1861 gtataaatga aaaaggcgat agtaccgatg cacagcatga tcaggcacaa caaaataggc
     1921 atcggaatat tggtatggaa actgccgctt tcatccgtat agccgaaata atcggcaatg
     1981 ggaacggtaa gcaccatagc caaagtggta ccgatacgtg cggttgccat ctcaagtccc
     2041 atagccaaag ccatctcttt acctttaaac catttcacga taatcttaga gacggtgata
     2101 ccggcgatct ctacgccgac accaaagata gcgtatccta aagccgccag aaagacctga
     2161 gtcttgaaac ccataatcaa agctccctca ggaaaagtag tagagatagc ataatatttt
     2221 agtccacaac ccaacaccat cagtatacaa gctcccatac cggtgaaacg aactcccatc
     2281 ttatcgagaa taataccacc gaaaatcaac atgagcagga atacattgaa ccatccgtaa
     2341 gcactggtaa agaatccgta gtccaaacta tcccagagaa gctctttctc gagcataggc
     2401 tttaaagggg acattacatc ggtgaggaaa tagccgcaaa gcatagtaaa cgcgaccaga
     2461 gcgagcacac tccaacgaag tgttttggag tcactcaatt tgtttttcaa ttgttctgtc
     2521 attgtaatat ttaaactcag aaattagtaa aagtgttatt gcgaacaaag gtaactaaat
     2581 ctgccttgta tgcctaacaa aaagatgcat tttacggcaa aaaataagcg aagctgcaag
     2641 tttcggtttg aaattgcagc ttcgcttatc gtttcttaaa aagaatctgt tgttagtttg
     2701 ccggagtagc cggagtttct gtggcaggtg cttcaaccgg agcagcagcg tctgtcttcg
     2761 gtgcagtagt acctacgggc aggttataag ggttggtctg ctcttcctgc tgtgcctgtt
     2821 ccataatgac atcttgtgtt ttagaagaag aagtcggaac gacatacgca gtagcaatgc
     2881 tcatcacaac cataaatgca gctaagcccc aagttgcttt ttccagaaag tctgtagttt
     2941 tgcgtacacc cataatctgg ttagatgatg agaaccctga agcaagacca ccgccttttg
     3001 agttctgaat caacacaatg aagcacatca gtatggctgc aataaccatt aagataacta
     3061 ataataagta cattttgtta ttttgattta gcgttaataa tcaatttctc taaaaatctg
     3121 atttggtctg caaagtaagc attttttttt ggatatttca aacttaattt tttaataatt
     3181 tcaagtgcct tggaatatcg atgctgtttg acgtatattt tggccaatgt ttcggtgaaa
     3241 cagctatcat cttcatcttc ttcatgatgc gtctcgctct cttcctcttc ggagatagct
     3301 ttattttcat ctgccggttg caaacggatg gatgtttctt cttcacttct ttcgataaag
     3361 ccgtcaatca attcatgacc gcgaagtttg ggagtttctt ccagttccgg tgtatcgtct
     3421 tcttgcagca aataggtggt atagtccgtt gcatagtcca ggcttgtctg ggctgaaacc
     3481 tcttcgggca cggtggccag aaaagcatcg attagggaaa gcgtacgatc gaggctgggc
     3541 tcttcctcta aaacttctgt ttcgggaagt gcgttctttt tccgaggttt caaaatatat
     3601 cgttcaccct caatcagata aaacagcttc cggcgatcag ccacatgcaa tatggcttta
     3661 cgaagctcgg caccgaaaga gatatcgtgc aacaaatata gatttttaag atagagtaat
     3721 cgcagtgact gaaaataagg atagcgtgtg acaagcgttc gcaactcgta caaagtatct
     3781 ttattcagcg tttccggatg ctgaatccat tgttgtaagt tagcagaaat cattctaatt
     3841 accagtttgc taccgttgcg ttaaatattt gatctgtaat ctctttggtc atctccgcaa
     3901 tcagtccgtc ctgaacggct gtcagcaact ccctcgaatc atagacacgg aaggccgaga
     3961 actgttgttc gaagtcctgt tcatgattcg tattgttcac aaaacgaaca ttcactgtga
     4021 tggtcagctt ggtttcagaa gagtatccgt cggccgaaac agcctggtta tactggttgt
     4081 atccggtaat ctctccatca atctcgaggt cggcattgtt attcaccagt ttcagacggg
     4141 tctgacgaag gaaaatgtct ttcaggtcct cgttgaactt agtgcctaac ggtgcataaa
     4201 catagtccga cttaatagga aagtcggcaa tagagatagt ctttacctta tcgtaattga
     4261 tattaccacc attaaactta taagaaacag tacacgaaat tcctactacc agtgtgaaaa
     4321 ccagcagtga aattcgcatt atctttttat tccaatccat attcttttat ttttcggtaa
     4381 agggtacgct cggatatatt aagatccttt gccgcgcttt ttcgcttgcc atgatgcttt
     4441 tcaagggctt tacgtatcat ttctttctcg acttcgtcca acgaaagcga ctcttccaca
     4501 tactcttcgg tatcttgtat gtcatcgtca tcgggacaat tgggcttgac cggatgaatg
     4561 attgcaggca ctgagggcgt aggggctact accggagccg gcgtataaaa cgtaccgaca
     4621 ttggaggtta ccgctccgcg ctcggacatg atttcgtgta caagcttttt cagttcggtc
     4681 acatcttgtc gcatgtcaaa aaggacctga tataagattt cacgttcact ttcgaagctc
     4741 ttccctgtct ttacaccgaa cagggcaggc aatcgctgcg tactctgggc aggcagataa
     4801 gattgcaaga taggggcatt aatctcacga ttggtctcaa ttatagagat ttgctccgtg
     4861 atattcttca actgacgcac gttacccggc caggaataag acagcaaaac ccgtttggca
     4921 tcttcggtca gctgtatggc gggcatacga tacttctctg caaagtcact tgcaaactta
     4981 cggaacagta acagcacatc ttctccacgc tcccgcaaag gagggatctg gatgggcacc
     5041 gtgttgagac gatagtataa atcctcacgg aaacgtccct ctgcaatggc ctgggtcaaa
     5101 ttgacattgg tagcagccac aatgcggaca tccgttttct gtactttgga ggagcctact
     5161 tttataaact ccccactctc gagtacacga agcaaacgtg cctgcgtggg caaaggcaat
     5221 tctccgactt catccagaaa aatagttccg ccgtcggctt caccaaaata gccctttcgc
     5281 tcaccgatgg ctcccgtaaa agcccctttt tcatgaccga acagttccga atcgatggtt
     5341 ccttcaggaa tagcaccaca gttgacagca atatactgtc catgctttcg gcgactgtat
     5401 tggtgaatga tctgagggaa actttcctta ccaacaccac tctctccggt tattagcacg
     5461 gacaaatcgg taggtgccac ctgtatggca acatctatcg cacgcgtcaa agcttcagtg
     5521 ttaccaataa taccgaacct tagttttacc tgttgtattt ccgcttttgt catattcgca
     5581 ctaaactccc ttcctgatta aatatcatca tctactgtat cgagcttcag tttatcactg
     5641 tcgtctcgtt tctcgtaata ctgtttacgt aacggattgg catgtgcttc cttctcacgt
     5701 tgacggttac ggaatacgtc gatcgctaca taaatagcct gacggaatga atcttcgcaa
     5761 gcaacgcctt ttcctgcaat atcataggct gtgccatgcg cgggagaagt gcgtatcacc
     5821 ggcaaacccg ccgtgtagtt cacaccttca tccatggcca atgccttgaa aggagccaat
     5881 ccctgatcgt gatacatggc cagtactccg tcaaaatggg tgaaattgcc cgatcccata
     5941 aatccgtcag ccggataagg gccatagcac aagattccct tggcagccat ttcctgaata
     6001 gcaggagaaa tgatttcctg ttcttctgta ccgagcaatc cgtcgtctcc ggcatgcgga
     6061 ttcagtgcca acactgcgat gcgcggtgca ccaatcccga aatcctgttt caacgaccgg
     6121 ttgaatatgg caagtttctc ctgaatcagt tccttggtta ttgaagaggc tatctcgcga
     6181 accggaatat gtcctgtcac caaagctacc cggaaatcct ctttcatcag gatcatcagt
     6241 gattttgaac cattccccag acgttgttcg atgtattccg tatgtccggg aaaagcaaat
     6301 ccttcggact gaatcgtatg cttattgata ggagccgtca ctatgacatc gatcaagcct
     6361 tccctgaact cctctatcgc cttctcaagt gctcccaaag ctgctttacc ggcttccgga
     6421 tcgggttttg agaactctac tttcacctcg tcatccgtac agttgaccac gctcaggcga
     6481 ttgtgggcag cttctgcagc ggtattgaca atactgaagt tagtaggcaa atcaagcgac
     6541 ttgcggtgat atgcagccac tttcggagag ccgtaaatga ccggtgtaca gagttccaac
     6601 atgacggggt cggcaaacgt ttttaaaatg acttcgtatc ctaccccatt tatgtctccc
     6661 tgagtgatgc caatttttat tttgttatct tccattttgt tatttgttag ttttctcctc
     6721 ctgctctatg cccatcggaa tctgttcctg cgccttctcg gtaggaagtt gcaaagtata
     6781 cagagatgct tccaatcggc gcatcaggtc acgtttcatt ttatcgggtg agtaaataaa
     6841 tacttctgta gtgataatac ggtggctggc tttatccaga cgggtgtgcg aaacaaacgg
     6901 gccacccatg aaatcgccct ttatgcgcca cagtccgcgt gcttccattg tgtaatctcc
     6961 atgaatatca atcggacgaa cctctacggt agacgaatca gtcgccatgt acataccctc
     7021 tttggcaccc ggaatattag ccttcatcac tgaatcgcgc ttatggataa agaactcttt
     7081 cgtaaaggta tccttatctg tatacgggta agagtagatt acaaagttct ggtctccggt
     7141 agcggcatta gtacctgccc agaaaaagtc ttctcctgtc ttcgaactgc tcagttcggc
     7201 cggaagccag atatcactgt tgaacatgct acctactttc gttgaaatat agtcattatg
     7261 atttttctcc aggaaagaga tctgacggtt catttcggca cgggtaaaga agtctataat
     7321 cggctgtttg ttctcttcga caaacttctc aaacgatgcc tcgtccggag cctgaatagt
     7381 caaaatcatc tggggagatg catatacatc cttggcatac ttgaatttag gttgggtata
     7441 aatgtcctgt atatctacga taataatgtt gcgcaccaac ttcaggatgg catcaaaatc
     7501 tttgggagaa gtagacatga tcctgaacga acgttccgat tgcggaagtc cgggcacatc
     7561 tgtatcaagc acattgtaca aagctctacc ggcaggacgc tcccacacag gcttctcaac
     7621 cacaacgagg acttcataag cacgtccgct ggaagttgga gtaaacacac tcttcttgcc
     7681 gcttttacaa gaaaacaaca ctactgctac aagagccata ctgaggtaaa acaggtactt
     7741 tttcatatgc atcaatttta atgttttcac aaatctacga aatggtcgta tactttcatc
     7801 caatgtgctg ataatttata ttaattcttg ttactctcct cctgtttagc cgtcgataac
     7861 atcccgcaag cggcaaaaat atcttctccc cgggaagctc gaatggtagt gaacagtcca
     7921 tgtgaggtca ggtagtcacg aaatgacgtc atagcctcca taccggcacc ctcgaggtct
     7981 accccaggaa tggcatgaaa ccggattaag ttcacccggc agtcaagccc acgcagcaat
     8041 ttcaacagct ccttagcata aatcagcgaa tcattgacgc ccttaaaaac aatgtattca
     8101 aacgaaagtc tgcgctgttt actaaaatca tagtttttta acagatcgac catttcttta
     8161 atcgagaaag ccctttcggc cggcatcagc tcagaacgtt gtgaaggaaa aggagaatgc
     8221 aggctgatag ccagatgaca ttcgctttct tcaataaagc gttgaagtcc tttccgcaat
     8281 cctacagacg acaaagtaat acgcttgggg ctccatccgt atccatacga agcggtcagg
     8341 atatgcagtg cttttaatac ttcatccaaa ttatcgagag gctcgcccat ccccatcatc
     8401 acgacattag tcaacttatc ccgctctggc aatgctgcga tttgattcaa gatctgattg
     8461 gctgtcagac ttgcggtaaa tccttgttta cccgtcatgc agaacttaca gttcatttta
     8521 cagcctacct gagaagacac gcacaatgtc gcccgatcct cgtccggaat atacaccgct
     8581 tcaacaaaat gattgtcact cacctgataa agatacttca ccgtaccatc tacggaacgc
     8641 atctcatcaa caggcgcgga tatccccaaa tcatactctc ccttgagcaa ctctctatgc
     8701 ttcaacgaca gattggtcat ttcatcaata gaagtcactt ttttatcgta taaccaggaa
     8761 gcgatctgtt tggctgcaaa agcaggcatc cccaaatctt tggtgacaga ttgcaattcg
     8821 gtaagggtca ttcctaaaag cggatatttg ggcatattta ctacaaatat ttatttattc
     8881 atgcaaatgt aaggaataaa agtcgatttt aaaaaagaga agggacaaaa gttaatagga
     8941 agagggaaag agatagcaaa aagaaaggcc gttccgtgcg gaacagcctt tcgtatatta
     9001 aaacgacgtt atctaaaaaa acaaatccgt ttttagaaga acaggtatcg tttatctttt
     9061 acatcgcctt tcagataaag atcgttcata aaacgacttg ccagacgggc atgcatgttt
     9121 tccaatgtag cctcttctga ttgggcatcg aatgtttcgt tcagcttatc tttggcatat
     9181 acctgcaaca caaacacacc gccattaccc ttgataggag cgctcagctt attgatatcc
     9241 gaaaccgaag cgtatgcgcc taccagcggc tcactactac gcaaagcggc tacataagca
     9301 ggcgctgcaa atgttacgtg ttttacagaa tcacttactg cattggccat cgatgtgtac
     9361 tgggcaattg tagttgcatt ggcagccttc atgtcggcca tgatcttctc agctttctta
     9421 tcacgaatga tttcagctct caactgatcc tgaacctggg ccaaaggacg ataaccttct
     9481 tcgatcacgc taaccagacc aa
//
