LOCUS       gnlProkkaOIKMCNEA_844   5927 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIKMCNEA_844.
ACCESSION   gnlProkkaOIKMCNEA_844
VERSION     gnlProkkaOIKMCNEA_844
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:40:38
            Original ID  :: gnl|Prokka|OIKMCNEA_844
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5927
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1701)
                     /NRPS_PKS="Domain: AMP-binding (11-401). E-value: 6.8e-84.
                     Score: 273.6. Matches aSDomain:
                     nrpspksdomains_ctg844_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (509-566). E-value: 8.2e-10.
                     Score: 31.0. Matches aSDomain:
                     nrpspksdomains_ctg844_1_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     261.7; E-value: 1.7e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg844_1"
                     /sec_met_domain="AMP-binding (E-value: 5.7e-89, bitscore:
                     286.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.3e-11, bitscore:
                     31.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNIQENLSRSLSTWGDKPAVVAKDGTVSYQMLERYSANIAQSI
                     RQRLSVTDPSGLRNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAEN
                     ADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNP
                     KGVRISYRNLDTFTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLIL
                     AGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNR
                     LKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGAT
                     GELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVK
                     IRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLR
                     AELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELKYVPPVHPGEVILCGILKEM
                     LGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRR"
     protocluster    1..5927
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:1701]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1701
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..5927
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5927
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        complement(4..174)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg844_1_PP-binding.1"
                     /evalue="8.20E-10"
                     /label="ctg844_1_PP-binding.1"
                     /locus_tag="ctg844_1"
                     /protein_end="566"
                     /protein_start="509"
                     /score="31.0"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLR"
     aSModule        complement(4..1668)
                     /complete
                     /domains="nrpspksdomains_ctg844_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg844_1_PP-binding.1"
                     /locus_tags="ctg844_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(472..534)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg844_1_0004"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg844_1"
                     /protein_end="410"
                     /protein_start="389"
                     /score="36.8"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        complement(499..1668)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg844_1_AMP-binding.1"
                     /evalue="6.80E-84"
                     /label="ctg844_1_AMP-binding.1"
                     /locus_tag="ctg844_1"
                     /protein_end="401"
                     /protein_start="11"
                     /score="273.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="SLSTWGDKPAVVAKDGTVSYQMLERYSANIAQSIRQRLSVTDPSG
                     LRNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSS
                     NEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPDDCAYIIYTSGTTGNPKGVRISYRNLD
                     TFTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLILAGEDERRDISL
                     LDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNV
                     YGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVS
                     LGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     CDS_motif       complement(607..693)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg844_1_0003"
                     /evalue="7.80E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg844_1"
                     /protein_end="365"
                     /protein_start="336"
                     /score="27.9"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       complement(1195..1251)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg844_1_0002"
                     /evalue="9.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg844_1"
                     /protein_end="169"
                     /protein_start="150"
                     /score="27.4"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       complement(1432..1473)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg844_1_0001"
                     /evalue="2.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg844_1"
                     /protein_end="90"
                     /protein_start="76"
                     /score="11.5"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS             complement(1714..4080)
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 168.9; E-value: 4.4e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg844_2"
                     /transl_table=11
                     /translation="MKRCLLYILCCFGVVQLSAQPADNIRNSFVKAETFYKSGDIDEAC
                     RILEENLSSFQGTMHTEACRLAALCCLALDRFPEAEKYVSLLLKDEPYYYISLQDPERF
                     ADMVRKHRETKVTLVTASQQVETPEEAPVPVTLITEEMIRAIHARCLRDVLIAYVPGIS
                     GLSSNEEMNLAMRGVYSPEQENILIMQDGQRLNSYITNAVSPDYGISLAKVKQIEVLRG
                     PASSLYGSVALTAVINIVTKDGVDVRNGSISVSAGNRGQLAADLLLGKHDMNMDFMAWF
                     SLYRATGESVFVPAEKQYALYPRDGFIRLDNYSGFPAMDGGIKLQRGNLLFSFSMNYAK
                     KRQPYSMWLFSSPYSYERFRTFDGSGPGYSRWSAREQAVYSRTWQRITFSTAFYTDWNK
                     NVHYETSGDTLQDYPIFPNYDYQPIIYPTRGAFQYIRWMDFNVGFNGRVNYAYDWGKLG
                     KGNMLGGVEWNRYTLYDSEYLEGMNFKEIVRTWIKKRLYTGHEMNTDAFLQIKHNLHKN
                     WIVNAGIRYDYKRRSNKRTLQAFSPRLSLIYLRNGLNIKASYSRAFVDAPYYYRNNETD
                     TYSGGENLQAEYLSSYQVTCAYHHSPSHIDVECNLFYNRASHFLFTQPETRVYENAGSL
                     DMGGVEVVARYKADRLSLDGNLCFQKVLNYTNFFVTDGSVNNVPGFSMNLVANYFLLKK
                     KVQSWSAHLKLNCSSHCYTQVSVLEDGLNGDATNYTVRLPGYAVFSFTTRYKYKRIEGS
                     LGIENLFNNRYECGGATVPIRQKGRWISASILYNF"
     CDS             complement(4077..4913)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 141.1; E-value: 1e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg844_3"
                     /transl_table=11
                     /translation="MEKNISQEKRIEELEARLKEQEKLGSLGLLSAGIAHEIQNPLNFV
                     INFSKLSGQLLADLADRVDEAKARIPEAELEDIKDILSGLRENVDKIKEHGDRAISIIR
                     GILLYSRGKEDEFMPTQIQKLTKEYVWLAYHAMRANYKNFNIAIREDYAKDIPSIRLIP
                     QDFSRAVLNVMNNACYAVWKKWQNAPEGYSPEIMVTLEKLDKRVVLSIRDNGEGMSPEV
                     KRKLFDSFFTTKPVGQGTGLGMAIVRDIIENKHHGKVLFDSVLHEYTCFRFIIPIA"
     CDS             complement(4936..5268)
                     /locus_tag="ctg844_4"
                     /transl_table=11
                     /translation="MSLLNNGMYAIAKKYGKKAYPAEIGLALESKDGQAVIRLYDNGVG
                     IEQSILDKIFDPFFTTKTTGEAAGIGLYLSKEIILNHHGQIAVRSEKDELTEFTITLPL
                     WEEKSV"
     CDS             complement(5265..5927)
                     /locus_tag="ctg844_5"
                     /transl_table=11
                     /translation="MLYTVAFGMLLFVLFKWRMRSLLKEKERLEALVGQRTKQLVQQKN
                     EIEEKSLKLEKALKELGQAQDELVRQEKMATVGKLTQGLIDRILNPLNYINNFSHLTSG
                     LLKDLYQNLESVKELLDEDTYLDSVDVINMMRDNLEKIEEHGSNTTRVLKAMEEILRDR
                     NRQLEKTELIGLCRKDMELLSSYYQKEITAMHIAVRTSLPDNPLFIDGNAEHWEKPL"
ORIGIN
        1 tcggcgcaga ttacgggcag tataaactgc agatacgttg atgggacatc cttttttatt
       61 ggcctcggta acaagcctca acatatccag cgaagttaat cccagatcat caatcaaatc
      121 ggcctcaaca ctgacttgag gcaaacctaa catttccttc aaaattccac ataagataac
      181 ctcccccgga tgaacaggag gaacatactt caactccaac gaagtaaaag ccgggagcgc
      241 ccggacatca atcttatcat ttatagtacg ctgaaaatga tctaccacct gccataaatt
      301 gggtatcatg tagtaaggaa gttctgcacg caaacgctct ttgacctctt ccggatgaaa
      361 gttaccggag actgagggtt gcaaataagc tcccaataat tgacgcccat tccgctcaac
      421 aactactacg tgggctctct ccacgtccgg atctctattc aatcgttctg ctatttcagt
      481 caattcgata cgaaaaccac gtatcttgac ctgagtatct tttcgcccga taaaccgtat
      541 tgaaccgtcc ggttgctgct gtaccaagtc acctgtcctg tacaaccgtt ctccatcgta
      601 cgagatgaat gatttttcat tcagctgaac actcccaata tatcccagcg aaacctgagg
      661 tcctcccaag caaagttctc ctgtagcccc aagagttgtc tgttggaggt tttcagacaa
      721 aacataacag acagttccct tgagcggata gccaatatcg tcatacgacg tatctttgcc
      781 tacaatccgt atggtactga gtacggtatt ctctgtcggt ccatatacat tcatcaaccg
      841 gtaaggctgc tgtttcagcc tgttaaataa cttttcacca atagcctccg caccaaagag
      901 cagagtctta aaggatggaa agtcaaggtc ggcaaacatg cccagcaacg aaggagggaa
      961 aaaagcaata ttcaccttct cgcgcctgat cagttcgtct agtaaagaaa tatctctgcg
     1021 ttcgtcctca ccggccagga tcaatgttcc tccgaccgga atacacatca tcagttctaa
     1081 tatggaagca tcaaaactga tactcgcaaa cgccagatac ctgtttgccg gatcagacaa
     1141 atgatacaat ttcttatcta ccagattcct cgtaaatgta tccagattcc gataactaat
     1201 acgtacacct ttgggattgc ctgttgttcc ggaagtatat ataatatagg cgcaatcatc
     1261 gggaagaact tcagtatagt caccaacaac cggttcggat agttgctccc cattcaggta
     1321 aagttggcgg acggacggaa ttccacctac ttcattcgat gaatcggtca acaacaaaac
     1381 catatccgca ttttcagcca tataccgttt acgattatcc ggcagcgagg gatctatcgg
     1441 taaataagtt gcccctaacc ggaaaatagc cagaatggca ggtactaaag ttttgtttcg
     1501 ttccatacaa actccgatac agatattccg aagtccggac ggatcagtta ccgataaacg
     1561 ttgacggata gattgtgcta tattggcaga gtaacgttcc agcatttgat aagagacggt
     1621 accgtctttt gcaacgaccg ccggtttgtc accccaggta gagagtgatc gagaaagatt
     1681 ttcttgaatg tttgttttca ttattagttt gatttagaaa ttatacaata tactggcgga
     1741 aatccacctt cctttctggc ggataggaac agtcgctcct ccgcattcat atcggttatt
     1801 gaaaagattc tcaatgccca gactgccttc tatcctttta tacttatatc tggtagtgaa
     1861 agaaaagaca gcataaccgg gcaaacggac tgtgtaattc gtcgcatctc cattgagtcc
     1921 atcttccaat acacttacct gagtgtagca gtggctactg caattcaatt ttaaatgggc
     1981 agaccagctc tgtactttct ttttaagtaa aaagtagttt gctacaagat tcatagaaaa
     2041 gccgggtacg ttattcacag atccatcggt aacaaaaaaa ttggtataat tcaatacttt
     2101 ctgaaaacac aggtttccat ccaggctcag tcggtctgcc ttataacggg caacgacctc
     2161 gacacctccc atatccagag aaccggcatt ttcataaaca cgtgtttccg gctgtgtgaa
     2221 caggaaatgg gacgcccgat tataaaataa attacactct acatctatat gtgaaggtga
     2281 atgatgataa gcacaagtca cctgatatga acttagatat tcagcttgca gattttcgcc
     2341 acccgaatag gtatccgttt cattgtttct gtaataatag ggcgcatcga caaatgctct
     2401 ggaataactg gctttgatat ttaatccgtt cctgagataa attagtgaca gacggggaga
     2461 aaaagcctgt aatgttcgct tattacttcg ccgtttatag tcatacctga tgccggcatt
     2521 gacaatccaa tttttatgca ggttgtgttt aatctgaaga aaggcatccg tgttcatctc
     2581 gtgtcccgtg taaagtcgtt ttttgatcca cgtcctgacg atctctttaa aattcatacc
     2641 ttccaaatac tcggaatcat aaagcgtata ccgattccat tccacaccgc caagcatatt
     2701 gcctttcccc agcttccccc aatcataggc atagtttaca cgcccattaa agcctacgtt
     2761 aaaatccatc cagcggatgt attgaaatgc tccgcgagtc ggataaataa taggttgata
     2821 atcatagtta ggaaaaatag gatagtcttg taaagtatct cccgaggttt cataatgtac
     2881 gtttttattc caatcggtat aaaatgcggt actgaaagtg atccgctgcc acgtgcggct
     2941 ataaacagcc tgttctcttg ccgaccacct ggaatatccc gggccggaac cgtcaaaagt
     3001 acgaaaccgc tcataagaat atggagaaga aaagagccac atgctataag gttgcctttt
     3061 cttcgcgtaa ttcatactga aactaaaaag caaatttcca cgttgcaatt taattcctcc
     3121 atccatggca ggaaatcccg aataattgtc cagacggatg aatccgtccc tagggtaaag
     3181 agcatattgt ttttcggccg ggacaaaaac cgattctccc gttgcacggt acaaggagaa
     3241 ccatgccata aagtccatgt tcatgtcgtg ctttcccaat agcaggtcag cagccaactg
     3301 gccccgatta ccggcactga cagatatgga accattacga acatccaccc cgtctttagt
     3361 aactatatta atcacggctg tcaaagccac actgccataa agcgaagaag ccggtccgcg
     3421 cagcacctct atttgtttga cttttgccag actaatacca taatccggcg aaacagcatt
     3481 agtaatataa ctgttcagac gttgtccatc ctgcataatc aatatgttct cctgttcggg
     3541 agaatatacc ccgcgcatag ccagattcat ctcttcattg gaagacaaac cggatatacc
     3601 gggcacataa gctatcagta catcccgcag gcaccgggca tggatagccc gtatcatctc
     3661 ctccgtaatt aaagtaacag gcaccggagc ttcttccggg gtctctacct gttgtgaggc
     3721 tgtgaccaga gttactttag tctccctgtg tttccttacc atatccgcaa agcgttccgg
     3781 atcttgaagc gagatataat aataaggttc gtctttcaat aacagcgaaa catacttttc
     3841 cgcttccggg aagcggtcta aagctaaaca gcataatgca gccaaacggc acgcctcggt
     3901 atgcatcgta ccttgaaaag acgacagatt ctcctccaag atacgacaag cttcatcgat
     3961 atctccgctc ttataaaatg tttccgcctt tacaaacgaa ttacggatgt tatccgccgg
     4021 ctgagctgac agttgcacaa ccccaaagca gcaaaggata tatagcagac agcgtttcat
     4081 gcgataggaa tgataaaccg gaaacaagta tattcatgca ggaccgaatc aaacaatact
     4141 tttccatggt gtttgttttc tataatatca cgaacgattg ccataccaag gcctgtcccc
     4201 tgccccaccg gttttgttgt gaaaaaagag tcaaatagtt ttcgtttgac ctccggactc
     4261 atgccctctc cgttatcacg aatagaaagt acaactcttt tatccaactt ttctaaggtc
     4321 accattatct cgggggaata tccttcggga gcattctgcc attttttcca tactgcatag
     4381 caggcattat tcatcacatt caagactgcc cgactgaaat cctgcgggat cagccggatc
     4441 gaggggatat ctttagcata atcttcacgg atagcaatat tgaaattctt ataattggcc
     4501 cgcatggcat gataagccag ccacacatat tccttagtca atttttgtat ttgtgtaggc
     4561 atgaattcgt cttctttccc cctggagtaa agcaaaatac cacgaataat gctgatagcc
     4621 cgatcaccat gctctttgat tttgtccaca ttctctctca gcccggaaag tatatctttg
     4681 atatcttcca gttccgcttc cggaatacga gcttttgctt catccaccct atcggccagg
     4741 tcggccaaca attgaccgga cagtttactg aaattgatga caaaattcaa aggattctgt
     4801 atctcgtgtg caatgcctgc actcaacaag cccaatgatc ccagcttttc ctgctctttg
     4861 agccgtgctt ccaactcttc aatacgtttc tcttgtgaaa tgtttttttc cataatcaat
     4921 ctgttctatg tttatttata ctgacttttc ctcccacaat ggcagagtga tagtgaattc
     4981 tgtcaattca tctttttcag aacgtactgc tatctgccca tggtgattta atatgatttc
     5041 cttactcaga tacaaaccga tacctgctgc ctctccggtt gttttggtag taaagaacgg
     5101 atcgaagatt ttatccagaa tactctgctc gatccccact ccattgtcat ataggcgaat
     5161 gactgcctgt ccgtccttac tttccaatgc caggccaatc tctgccggat aggctttctt
     5221 accgtatttt ttggctatgg catacatacc attgttaaga agactcataa tggtttttcc
     5281 cagtgttcgg cattcccgtc aataaacaac ggattatcgg gcaaggaagt acgaaccgca
     5341 atgtgcatag ccgtaatctc cttctgataa taactgctca atagctccat gtctttccgg
     5401 cataaaccga ttaattctgt tttttccagt tgcctgttac ggtctctcag gatttcttcc
     5461 atggccttca gtacacgagt ggtgttactt ccatgttcct caatcttttc cagattatct
     5521 ctcatcatgt tgatgacatc taccgaatcc aagtaggtat cttcatccaa aagttctttt
     5581 acactctcca gattctgata tagatccttc agtaatcctg aggtcaggtg ggaaaaatta
     5641 ttaatgtaat tcaacggatt cagaatacgg tcaatcaacc cttgagtcag tttgcctaca
     5701 gtagccattt tttcttgtcg aaccaattca tcttgtgcct ggcccagctc cttcaatgct
     5761 ttttccaatt ttaaggactt ttcctcaatt tcattttttt gttgtaccaa ctgtttggta
     5821 cgttggccga caagggcctc taacctctcc ttctctttca gcaaactgcg cattctccat
     5881 ttaaacaata cgaacaacag cattccaaaa gcaacggtat ataggat
//
