LOCUS       gnlProkkaOIKMCNEA_864   5628 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIKMCNEA_864.
ACCESSION   gnlProkkaOIKMCNEA_864
VERSION     gnlProkkaOIKMCNEA_864
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:40:38
            Original ID  :: gnl|Prokka|OIKMCNEA_864
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5628
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5628
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1444:5628]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1445..5628
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..5628
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5628
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             127..1431
                     /locus_tag="ctg864_1"
                     /transl_table=11
                     /translation="MIYMFTRMIRSLLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTA
                     AIYEGEILWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVAL
                     LGFALLPVPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKT
                     LGQFVMDNLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKD
                     RRKFLRQFFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFV
                     LVLMFLIVFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMG
                     YIPFTYLIERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRT
                     ALFSGFVSVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             1445..2143
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg864_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.7e-15, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             2163..3464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg864_3"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-13,
                     bitscore: 39.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.6e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.3e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             3476..4612
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 71.8;
                     E-value: 7.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg864_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-23, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-21, bitscore:
                     64.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGVALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             4609..5628
                     /NRPS_PKS="Domain: Aminotran_5 (30-292). E-value: 5.8e-34.
                     Score: 109.4. Matches aSDomain:
                     nrpspksdomains_ctg864_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 79.5; E-value:
                     3.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg864_5"
                     /sec_met_domain="Aminotran_5 (E-value: 3.5e-32, bitscore:
                     100.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     "
     aSDomain        4699..5484
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg864_5_Aminotran_5.1"
                     /evalue="5.80E-34"
                     /label="ctg864_5_Aminotran_5.1"
                     /locus_tag="ctg864_5"
                     /protein_end="292"
                     /protein_start="30"
                     /score="109.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAI"
ORIGIN
        1 aatatagcta atccttataa ttctttattt atggataaat agatttctga gtgtttttta
       61 tttagcgaat agaatatttt tacattcagc cctgttaaat cgtaatttga attgtcgtta
      121 cattggatga tttatatgtt tacacgaatg attcgttccc ttctttcccg ttctcccctt
      181 tacgttttgg ctctctatgc cagcgttttg atttttctgg tttatacctg tgcctatgcc
      241 taccgtaagc catttaccgc agccatttat gaaggtgaga ttctttgggg attcgatgtc
      301 aaaatcctgt atgtcctttc tgagattatc ggctacgccc tttccaagtt catcggtgtt
      361 cgtattctgc cttcgatgaa agcgggtcac cgcatctatt atataatagg gctgcttact
      421 ttttccgaag ttgctttgtt gggttttgca cttcttccgg ttcctttgaa ggtgtgttct
      481 atttttctga gcggtcttcc cctgggtatg atctggggtg tcatttttag ctatatcgaa
      541 gggcgtcgta tcagtgaaat attgaatgtc gggctgagcg ttgctttgat agtctcttcc
      601 ggtttggtga aaaccttggg acaattcgtg atggataatt tgcatgtgtc ggaatattgg
      661 atgcctttta ccaccggttt gttggtatac cctgttatgt tgctttgcag ctggcttctc
      721 aatcagattc cggctcccaa tgagcaagat atcatacagc gtaccaaacg tgctccgatg
      781 gatggtaaag acaggcgtaa gtttttgagg caattctttt ggggaatctg catgctggtt
      841 gttttttacg gtgccctgac cgtgttccgt gagcttcgtg actctttcgc tgccgatatt
      901 tggaaggagc tccatattga gggtgcaatg atctttactc agacagaggt tcccattgcc
      961 gtttttgtcc ttgtactgat gttcctgatt gtgtttgtcc gtaataaccg tttggctctt
     1021 aatatcattt attgcatcgc cgtcacaggc ggttccttaa tggttttttc cacattgctt
     1081 tatgtgtacg gttttctttc tcctatttgg tggatgattc tttccggtct tggtctgtat
     1141 atggggtata ttcctttcac ttacctgata gaacgtctga ttgcttccct tagggtggtt
     1201 agtacggctg tttttattat ttatttggcc gattctttcg gctatctggg cactacgggt
     1261 gtgtttatgg tcaagaactt cgtttctgct gacatttcct ggactgtcat gctgatgcgt
     1321 actgcccttt tttcaggatt tgtttctgtc ctgtcgattt ttgcgattta ctgttatttc
     1381 aagcaacaat tgaattcact tatattaatt ccctctgaaa ttcatgatta aaacagcaat
     1441 gatcatggct gccggtcttg gtacccgctt cgggcattat accgagcttg tgcccaaagg
     1501 ttttgtggag gttggtggaa aacctatgat tatccgctct atcgaaaccc ttctttcctg
     1561 cggtatcgaa cgtatcatcc tcggtacggg ttataaaaaa gaggcttatg aagcccttca
     1621 ggcggatttc ccccagatag agacctgttt cagtccccgt tatgccgata ctaacagtat
     1681 gtacactctg tacaatacgc gtgacgtgat aggcgatgac agtttcctgc tgcttgaatc
     1741 ggaccttgtt tttgaacgca aggccatcct ctcgctgctg gatgacgaat tcccggatgt
     1801 gatgcttgtc tcttctctga ccaagttcca ggatcagtat tatgtggaat atgaccgcaa
     1861 tcacatcctt acttcctgtt cggtagacaa ggacgccctt gaggcaaaag gcgagctggt
     1921 cggtatccat aaactttcca atactttcta ccgccggatg tgcgccgatt atgcgaccat
     1981 cctggagtcc cagcctaaac tgggttacga gtacgaactg ctccgcatgt cccgttccgt
     2041 ttcccctgtc cgtgtgctca gggtggaggg tcttaaatgg tatgaaatcg atgatgaagc
     2101 cgacctttcg tatgctgagg agcacatcat ccgctattgt taaaaacaaa tcttttccat
     2161 atatgaacaa gaaaatctat gtcggtatga ccgcggatat catgcatccg gggttgatcc
     2221 atattattca tgaagctact aaatacggtg atgtcatcgt cggtctgctg acggacaagg
     2281 ccatcgccga acacaaacgc ctcccttacc ttacctatga tcagcgtaag gaggttgttg
     2341 agaatatcaa aggggtttgc gaagttgttc cccaggagga ttggagctat gttccgaatc
     2401 tggaaaaact caagcctgac tatatcatcc acggcgacga ctggaaaacg ggcccgttgc
     2461 gcgaggtgcg cgaacaggtt tttgaggtga tgaacgccca ggggggcaag gtaatcgaga
     2521 tcccttatac ccggggcatc aactcctcct cgctcgacaa ggatatcaag gcgatcggga
     2581 ctacccctga cgtacgtctt aagtccctcc gccgcctgat ccaggccaag cctgtggtcc
     2641 gtatcctgga ggctcacgac ggtctttgcg gtctgattat tgagaatctt gaagtccaga
     2701 agggtgataa gcgcgaggtc tttgacggca tgtggtccag cagcctgacc gactccacga
     2761 gtaagggtaa accggatatt gaagcggtcg accttaccac ccgtttacag gacctgaaca
     2821 atatccttga atgtaccacc aagcctatta tttttgatgg agacacgggt ggcaagatcg
     2881 aacactttgt ctttactgtg cgcactctgg aacgtcacgg catttctgcg gtaatcattg
     2941 aagataaagt cggtctgaag aagaattctc tttttggtac tgacgctatc cagactcagg
     3001 atagtatcga gggtttctgc gataagatca gagcagggaa gaatgcccag gtcaccggtg
     3061 actttatgat cattgcgcgt atcgaaagcc ttattgccgg caaacccatg agtgacgccc
     3121 tcgaacgtgc ttatgcctat gtacaggcgg gtgcggacgg catcatgatc cacagcaagg
     3181 ataagtcggg tgaggatatc cgtgagttct gccggacttt ccgcaaagaa tacgcccatg
     3241 ttcccattgt cgttgttccg acgacttatg accatgtgca cgaatccgaa cttcacgaat
     3301 ggggtgccaa cgtagtcatt tacgccaacc accttctccg tgccgcttat ccggccatga
     3361 tgaacgtggc caggaccatc cttgaaaacg agcgcgccga ggaggtccgt ccgctttgta
     3421 tgcctatcaa ggaaattctg gaattgattc cgggcactaa ataaatcaga cggttatggt
     3481 aagtgtagaa aagatatacg atacgttcct tcatcacggt gttgacttct ttacgggtgt
     3541 tcccgattcc cttttgaaga atatttgcgc ctatatcacg gatcatgctc cgcgtggtaa
     3601 gcatatcatc gccgccaatg aaggttccgc ggtgggcatt gcctgcggtt attatatggc
     3661 ttctggcaac gttcctttgg tttatatgca gaactccggt ctgggaaata cggtgaatcc
     3721 cctcttgtcc cttgcggacg agaaagtgta cagccttcct cttcttttgc tggtcggctg
     3781 gcgcggtgag cccggcacga aagacgaacc ccagcataag aagcagggcg aggttaccct
     3841 tgatcttctg aaagccatga aaattccttt tataattctg gatacggatg aagacgaggc
     3901 cctggcgcag atccatgacg cggttgtctc ggcgaagagc cggtcgattc cccatgcgat
     3961 tgtcatccgt aaagatacgt ttggaaaata taaattgcgt caggaagcct tgaatgacta
     4021 tcctctgtcc cgcgaggagg cgctaatgca ggttgtcgac cacctcgggg acaatgacat
     4081 tgtggtttcc accacgggca agctctcccg tgagcttttc gagtaccgtg aatcgaaagg
     4141 gcaggggcac gcaagggatt tcctaactgt gggttccatg ggtcacagtt cttccattgc
     4201 cctgggggtt gcccttgaga agcctgaccg ccgtgtctac tgtcttgacg gtgacggtgc
     4261 ctttatcatg cacatgggtg ctgtcagcaa tatcggcgat ctttctccca agaattacag
     4321 gcacgtcctt ttcaataacg gtgcccatga atctgtcggc ggtcaaccca cgctcggttt
     4381 ccgtctggat atcgcctcga tagcgaaagg ttgcggttat gcgcatgtac tgactgcctc
     4441 cgacaaggaa gggctttcgt gtgcgcttga gaagctgtcc ggcctgtccg gcccggttct
     4501 tcttgaaatt aaggtccgga tcgattcacg tgatgatctg ggtcgcccta cgactactcc
     4561 ggtagagaat aaagagcatt ttatggcatt tttaaaagat acgcattcat gaatatcgaa
     4621 agaaagatcc ttttgaatcc gggtcccgcc accacgacgg atacggtgaa gctggcgcag
     4681 gttgttcccg atatctgtcc gcgtgagaaa gagtttgcgg gtatgatgaa acagttacgt
     4741 gacgacctgg tccgcgttgc gcatggagac ctctccaaac atacggccgt cctgttttgc
     4801 ggctcgggta cgatcaatat cgatatctgc ctgaactctc ttcttcctgc ggataagaaa
     4861 gttctggttg tcaataacgg tgcctacagc acccgtgcgg tggaagtctg cgaatattac
     4921 ggtcttcccc atatcgattt gaagttttcc gtttacgaac ttcccgacct gtcggtaatc
     4981 gaaaagacgc tttccgacaa tccggacatc gctttggtct ataccacgca ccatgaaacg
     5041 ggtacgggta tcttgaaccc catccgtgag atcggaaaaa tagcccattc gcacggtgcc
     5101 gtttttgttg tcgacaccac ttcctccctg ggtatgattc cttttgatat cgggaaggat
     5161 aatgttgact tttgtatggc ttcggctcag aaaggccttc aggccatgac ggggctttcc
     5221 tttatcatag gtgatgaatc cctgatacgt gcttcaaggg attatccgaa acgttcctac
     5281 tattgtaacc tctatttaca atacgattac tttgagaaga cgggcgagat gcattttact
     5341 cctcctgttc aaaccgttta cgctgcccgt caggctcttg atgaatattt tgcagtaggt
     5401 gaagaggcta aattcgcccg tcacaagagg gtctttgaag ccatccataa aggtttgcaa
     5461 gagcttggtc ttcagtatgc gatcaaacgt gaatggcagt cgggtcttgt tgtttctgta
     5521 ttgtatcctg atgatcccct ctgggatttt gataaggttc atgattactg ctatgaacgt
     5581 ggctttacga tctacccggg taagatttcc acaacgaata cattccgg
//
