LOCUS       c00457_gnlPro..        12836 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIKMCNEA_457.
ACCESSION   c00457_gnlPro..
VERSION     c00457_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:48:31
            Original ID  :: gnl|Prokka|OIKMCNEA_457
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12836
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12836
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[99:3344]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      100..3344
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12836
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12836
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..103)
                     /locus_tag="ctg457_1"
                     /transl_table=11
                     /translation="MKKLESSLKNMLLVLTGVTAISVALLAYVNELTK"
     CDS             complement(100..1092)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg457_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 6.9e-120,
                     bitscore: 389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFIVSLVYFGLGA
                     LIVTATSVIACLFFEWAIGKFLLKKETTTICDGSAVITGVLLAFNLPSNLPVWIIILGA
                     LFAIGVGKMSFGGLGNNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTAATPL
                     ALMKQAIHGDVSAFGQLPDAWSLFIGNNGGCLGEVSAAALILGLLYMLWKRIITWHIPV
                     SILVTVFVFSGIMHLANPEAYVSPVIQLLSGGLMLGAIFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(1098..2435)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg457_3"
                     /sec_met_domain="Fer4_7 (E-value: 1e-09, bitscore: 28.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 8.3e-17, bitscore: 50.6,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2e-51, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 8.9e-32, bitscore: 98.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.4e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIVTAEVPAKAVILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEANGFVSAAIHSSVSGKVAKIDSIVDASGYAKPAIFIDVDGDE
                     WEESIDRSPELVKECELTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVAILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSVAQPSNFLARIGTPMQQLIDACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNRKEAKRGEVQNCIRCAKCVSACPMGLEPYLLSALAENTEFERM
                     ESERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             complement(2472..3344)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36.6; E-value:
                     1.8e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg457_4"
                     /sec_met_domain="Fer4_7 (E-value: 9.1e-13, bitscore: 38.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.6e-09, bitscore: 26.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.3e-09, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.2e-09, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.5e-09, bitscore: 27.4,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.6e-11, bitscore: 32.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.5e-07, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAVLYVASKKFAVYEDPRIAQVSEVLP
                     QANCGGCGYPGCSGFADACVKAGSLEGKFCPVGGQPVMSQVASILGLDAGTAEPMVAVV
                     RCNGTCTNRPRTNMYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACVKACPKAIIELRAKGKKSRRVYVSCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDYNKCKSCRKCVEVCPQHTIIELNFPPRKPKEEMPV
                     AEAAKTAEA"
     CDS             complement(3350..3769)
                     /locus_tag="ctg457_5"
                     /transl_table=11
                     /translation="MTNIITHQGIVENISGSQVFVRIIQTSACSTCSVKGHCSSADSKE
                     KVIEVTDTSSAWKIGDKVTIIGATSMGMQAVLLAFLIPLFLLIFGLFIFKTVLHSELYG
                     AFAALAVLIPYYYIIWLNRTRLKQKFSFTIKPINN"
     CDS             complement(4020..4424)
                     /locus_tag="ctg457_6"
                     /transl_table=11
                     /translation="MIKQDYLIRMIQEIISLIVNAILNKKKFRKDEWTEYDCLTRQILG
                     VSQEELLSMSLDEMIDCYEGDPNRMGKIELAAVTLLKVSDEAESDILQKSKLRQDGLSL
                     LKYVQKESSTFSIQRTNLIRMIEINESLKM"
     CDS             complement(4553..5986)
                     /locus_tag="ctg457_7"
                     /transl_table=11
                     /translation="MKTSHISTLAFAILFSSSVMAQKTNKPVSETVQSEVKADTLSETL
                     QQYLVLKLNLDGPKPKIDTVSILYNKYIGELEYLNDPSVPMRYIKTDPDYYRLFVPLTY
                     YNSPIAEYSTMHWKFKEPFVTPSLSSQLLPPYDTLQFSKAERASRLVNVALMDLYLNHP
                     NLVVNTEDHIMSRKLYHGDKKIEVPKTEVKSLFRADKVEDNVGEAEMVISKPNWWVTGG
                     NGSLQITQNYISDNWYKGGESNNAVMANLQLFANYNDREKVQFENLFEAKLGFNSSPSD
                     EYHKYLVNTDQLRLYSKLGIQAANNWYYTITGEFKTQFVKGYKANSEELVAAFLAPADV
                     IVSVGMDYKLKKKKFNLSVFMSPLTYNLRYIGNKNVDETKFGLDKGKCSKNDFGAQVQP
                     TISWTIIPSIVVDSRLNYLTNYKWVRVEWENTFNFVLNRYLSTKLFVHARFDDSAKPTT
                     GSSYFQLKELLSFGLNYKW"
     CDS             6072..6179
                     /locus_tag="ctg457_8"
                     /transl_table=11
                     /translation="MNLYNNSAVLLERALSLRTIQIELRTAFPRLDSAS"
     CDS             6370..7971
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg457_9"
                     /sec_met_domain="GATase (E-value: 7.6e-56, bitscore: 178.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGQNALCVHLTYVPFLSAAQELKTKPTQHSVKELQSLGVQPDILVLRTEHDLNTNL
                     RKKVALFCNVAENAVVQSIDASTIYEVPLLMQEQGLDETILQKMGLPVGERPPLGPWKD
                     FLNRRANATETVTIAMVGKYVELQDAYKSILESLSQAATYNDRKVKIEYVSSEHLTPDN
                     VDEQLGHVNGVVICPGFGSRGIEGKFVAAKYTREHNIPTFGICLGMQCMAIEFARNVLG
                     YADANSIEMDEKTKHNVIDIMEEQKAITNMGGTMRLGAYECVLKKDSKVYEAYKEEHIQ
                     ERHRHRYEFNNDYRKQFEEAGMKCVGINPESDLVEIVEIPTLKWYIGTQFHPEYSSTVL
                     HPHPLFVSFIKAAIDK"
     CDS             8020..9876
                     /locus_tag="ctg457_10"
                     /transl_table=11
                     /translation="MDKNTITGLVLIGILLVGFSFLSRPSEEQIAAQKRYYDSIAVVQQ
                     QEEALRAKTEAALANEKEETAADSASLFFNATKGKEAFTTIQNNLVEITLDNKGGRVYS
                     ALLKNYMGQDKKPVVLFNGSDASMNFNFYNKKGALQTKDFYFEAVNKTDSSVTMRLAAD
                     SASYIDFIYTLKPDNYLMSFVIKATGMDGKLAASTNYVDISWSQRARQIEKGYTYENRL
                     ADLTYKYTGDDVDNLSASKDDEKSVSERLDWIAFKNQFFSSVFIAEQDFEKTTVKSKME
                     KQGSGYIKDYSAEMSTFFDPTGKQPTDMYFYFGPNHYKTLTALDKGREEKWELNNLVYL
                     GWPLIRWINKWITINVFDWLSGWGLSMGIVLLLLTIMVKIVVFPATWKTYMSSAKMRVL
                     KPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLLQFPILMALFMFVPSA
                     IELRQQSFLWADDLSTYDAFITFPFHIPFLGNHLSLFCLLMTVTNILNTKYTMQQQDTG
                     AQPQMAAMKWMMYLMPIMFLFVLNDYPSGLNYYYFISTLISVVTMIILRRTTDENKLLT
                     ELEAKKKDPKQMKKTGFAARLEAMQKQQEQLAKERANKQNKK"
     CDS             9965..11296
                     /locus_tag="ctg457_11"
                     /transl_table=11
                     /translation="MTTKYTYKEIWIIAYPILISLIMEQLIGMTDTAFLGRVGEVELGA
                     SAIAGVYYLAIFMMAFGFSIGAQILIARRNGEQQYQAIGPIFYQGVYFLLSLAVVAFTL
                     SLCFSPHILKKVISSEHIYDASISYINWRVFGFFFSFVGVMFRAFFVGTTQTKTLTLNS
                     VVMVLSNVVFNYILIFGKFGAPQLGIAGAAIGSSLAEMVSVIFFVIYTWRRIDCKKYAL
                     NHLPGFRPEMLKRILNVSFWTMIQNFFSLSTWFMFFLFVEHLGERALAITNIIRNVSGI
                     PFMVTMAFAATCGSLVSNLIGAGEIKCVPGTIRQHIRIGYIFVLPLVILFALFPNLILS
                     IYTDIPDLREASIPSLWVLCSAYLILVPANVYFQAVSGTGNTRTALGLELCVLAIYLIY
                     ITYMILYLRVDVAVCWTTEHLYGICILFLSYLYIKKGNWQKKQI"
     CDS             11394..12836
                     /locus_tag="ctg457_12"
                     /transl_table=11
                     /translation="MSAAMMLASCGGTKDAGKTDQALIGKSDIKIEGKRMTPEALWAMG
                     RIGGLAVSPDGKQIAYTVAYYSVPENKSNREVFVMNADGTDNRQITHTPYQENEVTWAA
                     DGSKLLFLSNDNGSSQLYEMNPDGSGRKQISKYDGDIEGYSISPDGKKILFIAQVKTVK
                     STADKYPDLDKATGIIITDLMYKHWDEWVTTAPHPFIADFDGKSISNIIDVLEGEPYES
                     PMKPWGGIEQLAWNTTSDKMAYTCRKKTGLAYAISTNSDIYVYDLNTKKTVNITEGMMG
                     YDTNPQYSPDGKSIAWQSMERDGYEADQNRLFVMNLETGEKRFVSKAFDSNVDAFIWSR
                     DAKTIYFTGVWHGETQIYSLDLANDSVRPVTSGMYDYEGVALFGDKLIAKRHSMSMGDE
                     IYAIALDGQTTQLTQENKQIYDQIEMGKVEGRWMKTTDSKEMLTWVIYPPQFDPNKKYP
                     TLLFCEGGPQSPVSQFWSYRWNM"
ORIGIN
        1 ctttagtcaa ctcattcaca taagccagca aagctaccga aatagctgtt actccggtga
       61 gtaccagcaa catatttttc aatgatgatt ctaacttttt catttcttct tcgctacctc
      121 cccaaagcgt tttggtttgc aatacgtatt gattagcgga gtgaatgcat tcataatcag
      181 aatagcaaac gacatacctt ccggatatgc accaaacaga cggataacaa ccgtcagcaa
      241 accgatgcag acaccataaa tcaacatacc ttttttactc atcggagagg tgacatagtc
      301 tgttgccata aagatagcac ccagcatcag acctcccgaa agcaactgga tcaccggaga
      361 aacataagct tcgggatttg ccagatgcat gataccggaa aatacaaata cagtaaccag
      421 aatggataca gggatatgcc atgtaatgat tctcttccat aacatataaa gaagacccaa
      481 aatcagggca gcagcactca cttcacccag acatccacca ttgttaccaa taaacagact
      541 ccaggcatcg ggcagttgac caaaagccga gacatcccca tggatagcct gtttcatcaa
      601 tgccaaagga gtggcggcag tagtagcatc ggtataagca gtcaactgac cgaccaccgg
      661 ccaggaagtc atctgtaccg ggaatgacaa taacagaaac acacgccctg ccagtgccgg
      721 gttaaacgga ttgttcccca agccgccaaa tgacatctta ccgacaccaa tagcaaacaa
      781 agcacctaaa ataataatcc atacaggtaa gttagacggt agattgaacg ccagcaacac
      841 tcccgtgatg acagcagaac cgtcacaaat agtagtggtt tctttcttca gcaagaactt
      901 accgattgcc cattcaaaaa acaaacaggc tatcacagaa gtagctgtga caatcagtgc
      961 acccagtccg aaatatacga gcgaaacgat aaaggcagga atcagcgcaa tcagcacacc
     1021 gtacatattc ttttgtacgc tgtctccacc atgaacgtga ggcgataatg atacaattaa
     1081 tttattttcc atacttatta ttttttagct tgacgtgcac gaatcatagc tcctactttc
     1141 cccttaccca gacgacagta gtcgagtaac ggacgattgg caggacaagt gaactggcaa
     1201 gagccacact cgatacaatc catgattctt tctgattcca ttctttcaaa ttctgtgttc
     1261 tcagccaaag cggaaagcag atacggctcc agtcccatcg ggcaggcact cacacacttt
     1321 gcacaacgaa tgcagttctg tacttctccg cgttttgcct ctttccggtt cataatcaaa
     1381 attccggaac ttcctttagc agtgggcaca tcagtattaa ccaatgcttt acccatcatc
     1441 ggaccaccgc caattatttt tccggtatcc tccggcaaac cgccacaggc atcgatcaac
     1501 tgctgcatcg gagtaccaat acgcgccaaa aagttagaag gctgggcaac agacttaccg
     1561 gtcaccgtaa tgacacgctc aaacaaaggc ttatttttct gtacagcttg atatacggca
     1621 aatgcagtac ctacattctg cacaactgct cctgtagaga taggtaatgc gccgcttgca
     1681 acctggcgct tcgtaatagc atcgattaac tgcttctcac ccccttgagg atatttcact
     1741 ttcaaaggaa caacttcaat accggcataa ctggatgcga ctttcgtcat cagttggata
     1801 gcatcgggtt tattgttttc gatacctata aaagccttat tgactttcac cgccttcatc
     1861 agaatagcca cccctaccat tacctcctcg gcatgttcca acatcagttg atggtcggct
     1921 gtcaagtaag gttcacactc tacagcgttg ataatcacgc attctgcttt aaatgaagga
     1981 ggcggacaaa gtttgacttg agttgggaaa caagctcctc ccaaaccaac aatgcctgca
     2041 tctgctatct tcttcacaat ctcttccgaa gtcaattcgc actcttttac caattcagga
     2101 ctacgatcga tagactcttc ccattcatcc ccgtctacat caataaaaat agcaggttta
     2161 gcataaccgc tcgcatcgac aatagagtca atcttagcga ctttaccact gacagaagag
     2221 tgaatggctg ccgaaacaaa gccattagct tcggctattt tagtgcccac cttcaccaca
     2281 tcaccttttg ccacaatagg cttagcaggc gcaccgatat gctgccccag cagtatcaca
     2341 gcttttgccg gaacctctgc cgtaacaata ggttgatgtg ctgagagttt attttcgtgt
     2401 ggatgaacac caccaattga aaatgtcttc aacatacaat tctgtatttt atctgtttat
     2461 tactcgtttt tttaagcttc ggcagttttg gcagcttcgg caacaggcat ttcctcttta
     2521 ggtttacgag gagggaaatt caactcgatg atagtgtgct gcggacaaac ttcaacgcac
     2581 ttgcgacaag acttacattt attgtaatcg atgtaagcga gattgttttc aagtgtaatt
     2641 gcctcgaacg gacaagtttt gacacactta ccacaaccga tgcaacttac cgtacaggct
     2701 ttgcgtgcga cagccccttt gtctttgttg acacaagata catatacacg acgcgatttc
     2761 ttacctttgg cacgaagctc gattatcgct ttcggacagg cttttacaca agctccgcaa
     2821 gccgtacact tttcttcatc cacctcagga agtcctgttt ccggattcat gtgaatagca
     2881 tcgaactggc aggcagccac acagtcgcca catcccaaac atccatagct acagccggtc
     2941 tctccgccat aaagcgaagc agcaatagca cagctctttg caccgtcata catatttgta
     3001 cgcggacggt tcgtgcaggt tccgttacat ctaaccactg caaccatcgg ttctgcagtt
     3061 ccggcgtcca atccgagaat agaggcaacc tgagacatca caggctgtcc acccaccgga
     3121 caaaacttac cttccagcga accggctttg acgcaagcat cggcaaatcc gctgcaaccc
     3181 ggataaccac atccaccgca gttagcctga ggcaacactt cggatacctg ggcaattcgt
     3241 gggtcttcgt acacggcaaa tttcttagaa gcaacataca atactgcagc caatacaagc
     3301 gcaatagctc ccaaagaaat cactgcaatc agaatcaaat tcataatttt tagttattta
     3361 ttggttttat agtaaaagaa aatttttgtt tcaaccgagt tctgttcaac catattatat
     3421 aataataagg aataagcacc gccaaagcag caaatgctcc atatagttca ctatgaagaa
     3481 ctgtcttgaa aatgaaaagg ccaaagatta aaagaaagag aggaatgaga aaagccagaa
     3541 gaaccgcttg catgcccatg gaggtggcac caataatcgt caccttgtcc cctatcttcc
     3601 atgcagacga agtatcggta acttcaatta ccttctcctt gctatctgcc gaagagcaat
     3661 gtcccttgac actgcaagtc gagcaagccg atgtctggat gatcctcaca aaaacctgag
     3721 aaccacttat gttttccaca ataccttgat gagttattat attagtcatt ttgcaaactg
     3781 cacattacaa attgcggcaa atttaagcat aagtttgaaa attacgaagt atttgaatgt
     3841 tttttatagt gcaatatgaa gtctttttaa agtaattttt gctctatcaa tcgggtatgg
     3901 atacagaaaa agcaggcttt tcacctgctt tactaagaaa atgttatcat cttctgatat
     3961 ttttaaagaa attagaaaca aaaaccaatt cttttatcac tttctgttta tttccccttc
     4021 tacattttaa gagattcatt aatctcaatc atccgaatca aattcgtccg ctgaattgaa
     4081 aaggtactgc tttctttctg aacatatttt agcaaggaaa gcccatcctg acgtaatttg
     4141 gacttttgca aaatatcaga ttccgcctcg tccgaaactt tcaacaaagt cacggccgcc
     4201 aattctatct tccccattct attaggatct ccttcataac agtcaatcat ttcatccagg
     4261 ctcatactta acaattcctc ttgagaaact cctaaaatct gtctcgtcag gcaatcatat
     4321 tcagtccatt catccttacg gaacttcttt ttattcaata tcgcatttac aattaacgaa
     4381 atgatttcct gaatcatccg tatcagatag tcttgtttaa tcataatatc ctctttttga
     4441 attagaactt acttaccacg gggagaatta acctcaccgg aaagaagaga gccgactgaa
     4501 gattccagtc ggcccctatt tcatatattt acattatgtc aattattccc gattaccatt
     4561 tataattcag accaaaactt agcaactcct tcagctggaa ataactgctg ccagtagtcg
     4621 gcttcgcact gtcgtcaaag cgtgcatgta caaatagttt agtagaaaga taacggttca
     4681 atacaaagtt gaaagtattc tcccactcta cacgcaccca tttatagttc gtcagatagt
     4741 tcaaacggga atcgactaca atagacggaa taatagtcca tgaaatagta ggttgaacct
     4801 gtgcaccgaa gtcattcttc gagcatttgc ctttatccaa tccaaacttg gtttcgtcca
     4861 cgtttttgtt acctatataa cgaaggttat aagtcaacgg agacatgaat acagaaagat
     4921 tgaatttttt ctttttcaac ttatagtcca taccgacact gactatcaca tctgcaggag
     4981 caaggaaagc agctaccaac tcttcactgt tagccttata tccctttacg aactgggttt
     5041 taaactctcc tgtaatagta tagtaccaat tattggcagc ctgaatacct aatttagaat
     5101 acaaacgcaa ctggtcggta ttaaccaggt atttatgata ttcgtctgac ggagaagaat
     5161 tgaatcctaa tttagcttcg aacagatttt caaactgtac tttctcacgg tcattgtagt
     5221 tagcaaacaa ctgcagattg gccattacgg cattattgct ctcacctccc ttgtaccagt
     5281 tgtccgaaat atagttctgg gtaatctgaa gcgaaccgtt acctcctgtc acccaccaat
     5341 tgggcttgga gatcaccatt tccgcttcac ccacattgtc ttccacctta tccgcacgga
     5401 acaggctttt cacttctgtt ttcgggactt caatcttctt atcgccatga tacaacttac
     5461 ggctcatgat atgatcttcg gtattaacga ctaaattagg atggttcaga tatagatcca
     5521 tcaaagcaac attcaccagc cgggaagctc tctcagcttt agaaaactgc aatgtgtcat
     5581 acggcggcaa taattgcgaa gaaagagagg gagtaacaaa aggttcctta aacttccagt
     5641 gcatggtaga atattccgcg atgggagagt tataataagt cagcggtaca aacagtcggt
     5701 agtaatccgg atccgtctta atataacgca tgggtacaga aggatcatta agatattcca
     5761 actctcctat atacttatta tataagatgg acaccgtatc tatcttaggc ttcggaccat
     5821 ccagattcag tttcaggaca aggtactgtt gaagcgtctc ggaaagtgta tctgctttca
     5881 cttcactctg cactgtttca gaaaccggtt tgttcgtctt ctgcgccatc actgacgaag
     5941 aaaacaggat cgcaaatgct aatgttgaga tgtgactagt cttcattttt ataacaaatt
     6001 tggggcaaat ttacattaaa tagtttagat tacataaaat ttgctcgatt ttaataggaa
     6061 taacctatca aatgaatcta tacaacaatt cagctgtttt attggaacgt gcattatctc
     6121 tcagaacaat acagatcgaa ctgagaaccg ccttcccccg gctcgatagt gcaagttgaa
     6181 taaaggcgtg cttatatgcc ggcaaacatg tgactgtttg tcgttcaaac atttcggtac
     6241 ccggaattgc attttttaat aaatttgttt tgtagaaagc atccgttctt ccccattttt
     6301 ttgtaatttt gcggttttta agattcaaat caaaggattt agaaacaaat tattaaaaca
     6361 gttatagctg tgggagaaac aaagtatatt ttcgtcaccg gtggtgttgc ctcttcttta
     6421 ggaaaaggta tcatttcatc ttccatcggt aaattgctgc aagcaagagg ttataaagta
     6481 actatccaga agtttgaccc gtacatcaac attgacccgg gaacattgaa cccttatgaa
     6541 cacggagaat gctacgtgac tgtagacggc catgaagccg atcttgactt aggacactac
     6601 gaacgtttcc tgggcatcca gacaacgaag gccaacaaca tcacgacagg ccgtatctat
     6661 aagagcgtca tcgataaaga acgccgtgga gattatttgg ggaaaaccat tcaggtgatt
     6721 cctcatatca ccgatgaaat caaacgtaac gtcaagttac tgggtaacaa gtataagttc
     6781 gactttgtaa tcacagaaat tggcggaaca gtaggtgata tcgaatcttt gccttatctg
     6841 gaaagtattc gtcagttgaa atgggaactg ggtcagaatg ccttgtgtgt acacctgact
     6901 tatgtacctt tcctgtccgc cgcccaagag ttaaaaacca aaccgactca acattccgta
     6961 aaagagttgc aatcactcgg tgtacagccg gatatcctgg tgctacgtac cgaacatgac
     7021 ctgaatacca acttgcgcaa gaaggtcgct ctgttctgta atgtagccga aaacgcagtt
     7081 gttcagtcaa tcgacgcttc aactatttat gaagtacctc tgttgatgca agagcaaggc
     7141 ctggacgaaa ccatactcca aaagatgggt ctgcctgtag gcgaacgtcc gccgttgggt
     7201 ccttggaaag acttcctgaa ccgtcgtgcc aatgcaactg aaacagtaac cattgcaatg
     7261 gtaggtaaat atgttgaatt gcaggatgcc tacaaatcta ttctggaatc cttgtcacaa
     7321 gctgctacct acaatgaccg taaagtaaaa atagaatatg tatcatccga acatctgact
     7381 ccggacaatg tagacgaaca attgggacat gtaaacggag tagttatctg tccgggattc
     7441 ggttcacgcg gtatcgaagg taagttcgta gctgccaaat acacccgcga acacaacatt
     7501 ccgacattcg gtatctgtct gggtatgcaa tgtatggcta tcgagtttgc ccgtaatgtg
     7561 ttgggttatg ccgatgccaa ctccattgaa atggatgaaa agaccaagca caacgtgatc
     7621 gacatcatgg aagagcagaa agccatcacc aatatgggag gtactatgcg tctgggagct
     7681 tacgaatgtg tattgaagaa agactctaag gtatacgaag cctacaaaga agaacacatt
     7741 caggagcgtc atcgccaccg ctacgaattc aacaacgact atcgcaaaca attcgaagag
     7801 gccggcatga agtgtgtagg tatcaacccc gagtccgact tggtagaaat tgtagagatt
     7861 cctacattga aatggtacat cggaacacag ttccatccgg aatacagcag taccgtacta
     7921 cacccgcatc cgttgttcgt gtcgttcatc aaggctgcaa tcgataagta aagatcgtta
     7981 tcgtatagat tattaatcat taatcactta aaaaagagaa tggataaaaa caccatcaca
     8041 ggcctcgttt taataggtat attactggta ggattcagtt ttctgagccg tcccagcgag
     8101 gagcaaatag ccgctcaaaa gcggtattat gactctatag ccgtggtaca gcagcaagaa
     8161 gaagcactga gagccaaaac cgaagctgcg ctggctaacg aaaaagaaga aacagcagcc
     8221 gactcagcat cgctcttctt caatgccacc aaaggtaaag aggcgtttac tactatccag
     8281 aataatttgg tagaaatcac tctggataac aaaggcggcc gtgtttactc tgccctgttg
     8341 aaaaactaca tgggacagga taagaaaccg gttgtgttgt tcaacggcag cgatgcttcc
     8401 atgaacttca acttctataa caagaagggg gccctccaga caaaagactt ctattttgaa
     8461 gcagtcaata agacagatag cagtgtaacg atgcgtctag ctgccgacag tgccagctat
     8521 atcgatttca tttatacact gaaacctgat aactacctga tgagctttgt gatcaaagct
     8581 acgggaatgg acggaaaatt ggctgccagc acaaactatg tggacatctc atggtcacaa
     8641 cgtgcccgcc agatcgaaaa gggatatact tacgaaaacc gtttggcaga cctcacctac
     8701 aaatacaccg gtgatgatgt ggataacctt tcggcaagta aagacgacga aaagtccgtt
     8761 tcggaacgtc tggactggat cgctttcaag aatcagttct tctcttccgt attcatcgca
     8821 gaacaggatt tcgaaaagac tacggttaaa tcgaaaatgg agaaacaggg aagcggttac
     8881 ataaaggact attccgccga gatgagtacg ttctttgatc cgaccggtaa acaacctacc
     8941 gatatgtatt tctacttcgg cccgaaccac tacaaaacgc tgactgcgtt ggataaggga
     9001 cgtgaagaga aatgggaact taacaacttg gtatatctgg gctggccgtt gattcgttgg
     9061 attaacaaat ggatcaccat caacgtgttc gactggttgt ccggctgggg attaagtatg
     9121 ggtatcgttc tgttgttact caccatcatg gtgaaaatag tcgttttccc ggcaacatgg
     9181 aagacctata tgtcatcagc caaaatgcgg gtgctgaaac cgaaaatcga tgagatcaac
     9241 aagaaatacc ccaaacagga agatgcgatg aagaaacagc aggaggtgat gggattgtac
     9301 agccagtacg gtgtaagccc gatgggtggc tgtctgccga tgttgttgca attccctatc
     9361 ctgatggcat tgtttatgtt cgtaccgagt gctatcgaac ttcgtcagca gagtttcctt
     9421 tgggcggatg acttgtcgac ttatgacgca ttcatcactt tcccgttcca tattccattc
     9481 ttgggtaatc acctcagttt gttctgcttg ctgatgactg ttaccaacat cctgaatacg
     9541 aagtacacaa tgcaacagca ggatacgggt gcccagccgc aaatggctgc gatgaagtgg
     9601 atgatgtacc tgatgccgat catgttcctc ttcgtcttga acgactatcc ttcgggattg
     9661 aactattact acttcatttc gactctgatc agtgtagtaa ccatgatcat actgcgccgg
     9721 acaactgacg aaaacaaatt gcttaccgaa ctggaagcta agaagaaaga tccgaaacag
     9781 atgaagaaga ccggatttgc cgcacgcctg gaagctatgc aaaaacaaca ggaacaattg
     9841 gcaaaagaac gggctaataa gcagaataag aaataagaga tagaaatcag cttaaatacc
     9901 gaagagccgg acaagcagtg tatgtttgtc cggctttctt ttcctttatt gaacagatta
     9961 caacatgact actaaataca catacaaaga aatatggatt atcgcctacc ccatcctgat
    10021 cagcctgatc atggaacagc tgataggcat gaccgacact gcttttctgg gacgtgtggg
    10081 cgaagtcgaa ctgggagcct cggccattgc cggtgtatac tatctggcta tttttatgat
    10141 ggcattcgga ttcagtatag gtgcacaaat cctgattgcc cgtcgtaacg gtgaacagca
    10201 ataccaggct atcgggccca tcttttatca gggtgtctac tttctgcttt cactcgcagt
    10261 ggtagcattc actctttcgc tgtgcttctc accgcacata ctgaaaaagg tcattagctc
    10321 ggagcatata tacgatgcgt ccatcagcta catcaactgg agggtcttcg gctttttctt
    10381 ctcctttgtc ggagtaatgt ttcgtgcatt cttcgtgggt acaactcaga ccaaaaccct
    10441 gacactgaac tctgtggtca tggtattatc caatgtggtg ttcaactaca tactgatttt
    10501 cggtaagttc ggtgctccac agttaggtat cgccggagcc gccatcggtt cgtcactggc
    10561 cgaaatggtt tcggtcatct tcttcgtcat ctacacctgg agacggatag actgtaaaaa
    10621 gtatgccttg aatcatctgc ccggattccg gccggagatg ctgaaacgga tcctgaacgt
    10681 atccttttgg acaatgattc agaacttttt ctcactgtcc acttggttca tgttcttcct
    10741 atttgtcgaa cacttaggcg aacgtgcact ggccataacc aatatcatcc gtaacgtatc
    10801 gggcatcccg tttatggtca ccatggcatt tgcagctact tgcggctccc tggtgagtaa
    10861 cctgatcggt gcgggcgaaa tcaagtgtgt tcccggaacg atccgccagc acatccgtat
    10921 cggttatatt ttcgtgctgc cgctggttat actcttcgca ctgtttccta acctgatatt
    10981 gagtatctat acggatattc ccgatttgcg ggaggcctcc atcccttctt tatgggtact
    11041 atgctccgct tatctgatac tcgtacctgc caacgtctat tttcaggcag tatccggaac
    11101 gggcaacaca cgtacggcat tgggattgga actctgtgta ctggccattt atctgatcta
    11161 tatcacctat atgattctct atctgagagt ggatgtagcc gtctgctgga ctacggaaca
    11221 tctgtacgga atctgtatcc tgttcctttc atacctttat ataaagaaag gaaactggca
    11281 gaaaaagcag atttgacctg atttttgctt atcttcgcag cactattatg gaagagaaca
    11341 caagtaaatt actaattatt aaaataacta tgagacaagt aaacctattt attatgtcgg
    11401 cagcaatgat gttagcatct tgtggtggaa ccaaagatgc aggcaaaaca gatcaggcgc
    11461 tgatcggtaa atccgatatc aagatcgaag gaaagcggat gactcccgaa gcgctttggg
    11521 cgatgggacg tatcggcgga ctggccgtat cgcctgacgg aaagcaaata gcctatactg
    11581 tggcttatta cagtgtcccc gagaacaaga gcaaccggga agtttttgtg atgaacgcgg
    11641 atggaacgga taatcgacag attacccaca ctccttatca ggaaaatgaa gtgacttggg
    11701 cggcagacgg aagcaagctg ctcttcctga gcaatgacaa cggcagcagc caactgtatg
    11761 aaatgaatcc ggacggtagt ggacgcaagc agatctccaa gtatgacgga gacatcgagg
    11821 gatattccat ctcaccggac ggtaaaaaga tactcttcat cgctcaagtg aaaacagtaa
    11881 agagcacggc tgataaatac cccgacctgg ataaagcgac cggaatcatc atcaccgacc
    11941 tgatgtataa acattgggac gaatgggtga ccaccgctcc acatcctttc atcgccgact
    12001 ttgatggcaa atcaatctcc aacatcatag atgtgctgga aggagaacct tacgaaagcc
    12061 cgatgaaacc ttggggaggt atcgaacaac tggcttggaa tacgacttcg gacaagatgg
    12121 cttatacctg ccgcaaaaaa acgggactgg cttatgccat atctaccaac tcggatatct
    12181 atgtatatga cctgaatacc aagaaaacag taaacatcac cgaaggtatg atgggttatg
    12241 atacaaaccc gcaatattct ccggatggaa aaagcattgc ctggcaaagc atggagcgcg
    12301 acggttacga agctgaccag aaccgcctct tcgtcatgaa cctggaaacg ggcgagaaac
    12361 gttttgtaag taaagctttc gattcgaatg tagatgcatt catatggagc cgggatgcca
    12421 agacgatcta cttcaccggt gtatggcatg gtgagacaca aatttattca ctcgatctgg
    12481 ctaacgattc cgtacgcccc gtcacttcgg gcatgtacga ctacgaaggc gttgccctct
    12541 tcggagacaa actgattgcc aaacgccatt caatgagtat gggtgacgaa atttacgcaa
    12601 tagctttgga cggacaaacc acgcaactga cccaagagaa caagcaaatc tatgaccaga
    12661 tcgaaatggg taaagtagaa ggccgctgga tgaaaacaac tgacagcaaa gagatgctga
    12721 catgggtcat ctatccgcct caattcgatc cgaataagaa gtacccgaca ctgctcttct
    12781 gcgaaggtgg tcctcagagt ccggtaagcc agttctggag ttatcgttgg aacatg
//
