LOCUS       c00630_gnlPro..        15211 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KEKHGNPL_630.
ACCESSION   c00630_gnlPro..
VERSION     c00630_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:48:49
            Original ID  :: gnl|Prokka|KEKHGNPL_630
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15211
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15211
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[26:5211]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      27..5211
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15211
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15211
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             27..908
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_1"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-09, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 9.4e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.5e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 1.6e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.2e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             933..2270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_2"
                     /sec_met_domain="Fer4_10 (E-value: 2.8e-09, bitscore: 27.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 7.8e-17, bitscore: 51.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.6e-51, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.4e-29, bitscore: 92.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSTTLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVANPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDHCRLGKGKVGAMIRARQAKK"
     CDS             2276..3283
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.8e-120,
                     bitscore: 392.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIHAADKSAAMDALNQIPDALSLLIGQNGGCLGEVSALALLIGLVYMLWKKIIT
                     WHIPVSILATVFIFAGIMHLADPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGM
                     LIYGVCIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             3310..4017
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_4"
                     /sec_met_domain="FMN_bind (E-value: 2.6e-23, bitscore:
                     73.0, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKGEQAVSHEESKKSILGMNPGEAPLTV
                     SKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEGGKVNGVSGASQKATGADSDTATGA
                     TIKVELTDSVSAK"
     CDS             4032..4616
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.9e-71, bitscore:
                     228.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVMMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATM
                     FVLICSNVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLI
                     VVNCIVLGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMP
                     EEYGMLVFVLAPGAFIALGYLIALINSFKKA"
     CDS             4639..5211
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg630_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.5e-63, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5435..6469
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg630_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.4e-51, bitscore:
                     166.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKTQKEKVEVFNIGTGRGVSVLELING
                     FERATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             6516..6605
                     /locus_tag="ctg630_8"
                     /transl_table=11
                     /translation="MRFVYLMLIDLKLFMSMRIYVNSTYASPA"
     CDS             complement(6726..7550)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg630_9"
                     /sec_met_domain="GHMP_kinases_C (E-value: 4.1e-10,
                     bitscore: 30.5, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.5e-10,
                     bitscore: 31.8, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSS
                     ETEKKITLHQYGMEIAGNPEDNLVAKAYSLLDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHFQLELSEEQLEVYAATLGADCAFFIKNKPTYAEGIGNLFSPIELSLS
                     GYQIMIVKPNVFVSTREAFSNIHPHRPEYPVKEAILRPVAEWKDILINDFEASVFPQHP
                     VIGEIKRELYHQGAIYASMSGSGSSVFGLFAPGTSLPETIGESDVFCFKGKL"
     CDS             7750..9312
                     /locus_tag="ctg630_10"
                     /transl_table=11
                     /translation="MAEQKRNTRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLIANVCEIPSEKIKS
                     GQLANYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKMNTGDAGSMPPPPAPDFAPQTANPFGAPGDGP
                     LPF"
     CDS             9425..11887
                     /locus_tag="ctg630_11"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPETAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGRQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVIVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAQDFIVDLAYGKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGLEAYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFNADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDVFAAALSVNTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNIQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDENQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             11921..12658
                     /locus_tag="ctg630_12"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGEE"
     CDS             12668..12913
                     /locus_tag="ctg630_13"
                     /transl_table=11
                     /translation="MEYVYKTQGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGISRLVR
                     GMKVEEVIAKLEGVRCGGRPTSCPDQLCHALHEMGY"
     CDS             13172..14425
                     /locus_tag="ctg630_14"
                     /transl_table=11
                     /translation="MKNIFQDLRRKDHKRYLGGLDVFKYIGPGLLVTVGFIDPGNWASN
                     FAAGSEFGYSLLWVVTLSTIMLIVLQHNVAHLGIVTGLCLSEAATKYTPKWVSRPILGT
                     AVLASISTSLAEILGGAIALEMLLDIPIIWGAVLTTLFVSIMLFTNSYKKIERSIIAFV
                     SVIGLSFIYELFLVEIDWPAATAGWVTPSFPKGSMLIIMSVLGAVVMPHNLFLHSEVIQ
                     SHEYNKKDDASIKKVLKYELFDTLFSMIVGWAINSAMILLAAATFFKSGIQVEELQQAK
                     SLLEPLLGSNAAIVFALALLMAGISSTITSGMAAGSIFAGIFGESYHIKDSHSQVGVLL
                     SLGIALLLIFFIGDPFKGLIISQMVLSIQLPFTVFLQVGLTSSRKVMGDYVNSRWSTFV
                     LYSIAIIVSVLNIMLLFS"
ORIGIN
        1 taaaaccaat aaataactaa aacattatga atttgattct gattgcagtg atttcattgg
       61 gagctatagc gctcgtgctg gccgctattc tttatgtagc ttccaagaaa tttgccgtgt
      121 atgaagaccc gcggattgcc caggtggggg aagtgttgcc ccaggcaaac tgtggtggat
      181 gtggctatcc tggatgtagc ggatttgccg atgcttgcgt caaagccggt tcgctggatg
      241 gtaaattctg ccctgtaggc ggtcagcctg tcatggcaca aattgctgat attctcggac
      301 tggcagctac tgaagctgaa ccgatggtag cagtagtaag atgtaacgga agctgtgcca
      361 accgtccgcg tattaatcaa tacgacggtg cgaagagttg cgctattgcc gcttcattgt
      421 atggtggaga aacaggttgt agctacggat gcctcggatg tggcgactgt gtggctgcct
      481 gccagttcga tgctatccac atgaatcctg aaacgggact tccggaagtg gatgaagcca
      541 aatgtacagc ttgtggcgct tgtgtaaagg cttgtccgaa ggcgatcatc gagattcgtc
      601 cgcaaggcaa gaaatcacgc cgtgtgtaca tctcttgtgt gaacaaagac aagggagccg
      661 tagcacgtaa ggcttgtaca gtgagctgta tcggctgtgg taagtgtgtc aagacttgtc
      721 cgttcgaagc cattacgctg gagaacaacc tggcttacat cgatccgaac aagtgtaaat
      781 catgccgtaa gtgcgtggaa gtttgtccgc agaacacgat tatcgagctg aacttccctc
      841 cacgtaaacc gaaggcagaa gaagcaccga aaacagttgc tgcagaagct ccgaaggtaa
      901 cagaataata acagaataaa atacagaatt gtatgttaaa gacattttca attggtggag
      961 ttcatccaca cgaaaataaa ttgtcggcac atcaacctat tatcacagcg gaagttcctg
     1021 caaaggctgt tattttgctg gggcagcaca tcggtgcgcc tgcaaaaccg gttgtagcga
     1081 aaggggatgt ggtaaaggta ggcacacgga ttgccgaacc tgccggcttt gtttcggcag
     1141 caattcactc ttcggtcagt ggtaaagtgg cgaagattga taccatagtc gatgccagcg
     1201 gttatgcgaa acctgccatc ttcattgatg tggaaggcga cgaatgggaa gagacaatcg
     1261 accgtagcac cacactggtg aaagagtgtg aactttccgc agaagagatc gtgaagaaga
     1321 ttgccgatgc cggaatcgta ggtctgggcg gtgcttgttt ccctacgcag gtgaaacttt
     1381 gtcctcctcc ttctttcaag gctgaatgtg tgattatcaa tgccgtagag tgtgaacctt
     1441 acctgactgc cgaccatcag ctgatgttgg aacacgcgga agaaatcatg gtgggtgttt
     1501 ctatcctgat gaaagcggtg aaagtgaaca aggcatttat cggaatcgaa aataataagc
     1561 ctgatgctat cgaactgatg accaaagtgg cttccagcta tgcaggtatc gaagtagtgc
     1621 ccttgaaggt gaaatatccg caaggaggtg aaaagcagct gatcgacgcg atcaccaaac
     1681 gtcaagtggc gagcggtgca ttgcctatct ctacgggagc agtcgtgcag aacgtgggaa
     1741 cagcatttgc cgtttatgaa gctgtacaga aaaataagcc gttgttcgaa cgtgtgatta
     1801 ccgtgacagg aaagtcagtt gcgaaccctt ccaacttctt ggctcgtatc ggtacaccga
     1861 tgaaacagtt gattgacgct tgcggtggtc tgcccgaaga tacgggtaag gtgatcggtg
     1921 gcggtccgat gatgggtaag gcgctcgtaa atatcgaggt tcctactgcg aagggcagtt
     1981 ccggtatcct gattatgaat cagaaggaag ccaaacgtgg tgaggcgcag acttgtatcc
     2041 gttgcgcgaa gtgcgtgagt gcctgtccga tgggactgga accgtacttg ctcggagctt
     2101 tgtccgaaaa cggagatttt gaaacaatgg aaaaagaaag aatcatggat tgtatcgagt
     2161 gcggctcttg ccagttcact tgtcctgcca accgtccgtt gctcgaccac tgtcgtctgg
     2221 gcaaaggcaa agttggtgct atgattcgtg cacgtcaagc taaaaaataa cgaatatgga
     2281 aaataaatta atcgtatcac tatcacccca cgttcatggc ggagacagcg tacagaaaaa
     2341 tatgtatggc gtgctgatcg cactgattcc ggcttttctg gtgtctctct atttcttcgg
     2401 actgggtgcc ctgattgtca cggctacttc cgttgcagct tgtttgttct tcgaatgggc
     2461 gatcgggaaa tatttaatga agaaacctac caccaccatc tgcgacggct ctgccatcat
     2521 cacaggtgtg ttgctggcat tcaacttacc gtctaatctc cctatctgga ttatcattct
     2581 gggtgcactg tttgctatcg gtgtaggcaa aatgtctttc ggcggattag gttgcaatcc
     2641 ttttaatccg gcactggcag gacgtgtgtt cctgttgctt tctttcccgg tacagatgac
     2701 cagctggccg gtagtcggac agttgaccgc ctatacggat gctaccaccg gtgccactcc
     2761 gctggcattg atgaaacaag cgattcatgc tgcagataaa agtgcggcta tggatgcttt
     2821 aaaccagatt ccggatgcat tgagtttgct gatcggacag aatggcggat gcttgggtga
     2881 agtgagtgca ttggctctat tgatcggact ggtttatatg ctctggaaga agatcattac
     2941 ctggcatatt cctgtgtcta tcctggctac cgtgtttatc tttgcaggta tcatgcactt
     3001 ggcagatccg gaaaaatatg tttctccgat attgcagttg ctctccggtg gtctgatgct
     3061 gggtgctgtc tttatggcaa ccgactatgt gacttctccg atgagtaaga aaggaatgtt
     3121 gatttatggt gtatgtatcg gtctgctgac ggttgtcatc cgtctgttcg gtgcttatcc
     3181 cgaaggtatg tcgttcgcca tcctgattat gaatgcgttc actccgctga ttaacaccta
     3241 ttgtaaacca aaacgctttg gggaggtagc gaagaagaaa tgaaaaagtt agaatcatct
     3301 ttaaagaata tgttgctggt acttacgggc gtgactgctg tctccgtagc gttgctggct
     3361 tatgtaaatg aactgacaaa aggccccatt gccgaagcga atgcgaagac actgaacgag
     3421 gctttgaaaa aggttcttcc cgaatttacc aataatccgg tagcggaaag cgatacgatc
     3481 ttcagcgaga aagacggaaa gaagaatgtt gactttatcg tttatccggc taagaacggc
     3541 gaagaattgg taggaacggc cgtcgaagct aaatcaatgg gatttggcgg cgaactgaaa
     3601 gtgttggtag gctttaacgc cgaaggtaaa atctataatt actcgttact cgctcacgcg
     3661 gaaactccgg gactgggttc taaagccgac aaatggttcg gagcatacga cccggccaag
     3721 ggagaacagg ctgtgtctca tgaagagagt aaaaagtcta ttttggggat gaatccgggt
     3781 gaagctccgt tgaccgtcag caaagatggg ggagcggtgg atgccattac agcttctacc
     3841 attacttcac gtgcgttttt gaatgctgta aatgctgctt atcaggctta taaggcagaa
     3901 ggtggtaaag tgaatggtgt cagcggtgct tctcaaaagg ctacaggcgc agactctgac
     3961 actgctacgg gagctacgat aaaagttgaa cttactgatt cggtcagtgc taaataagaa
     4021 aggagacaga tatgaataac tttaaagtaa tgatgaacgg gattatcaaa gagaatccta
     4081 cgtttgtact cctgctcggt atgtgtccta cattgggtac gacttcgtcg gccatcaatg
     4141 gtatgggtat gggactggct accatgttcg tattgatctg ctcgaatgtg gtgatctctt
     4201 taatcaagaa cctgattccg gatatggtgc gtatcccgtc gtttatcgtg gtgatcgcgt
     4261 ctttcgtaac cttgcttcaa atggtgatgc aggcatacgt gcctggactg tacgctacgc
     4321 tcggactttt catcccgttg attgtagtga actgtattgt gttgggacgt gccgaagcat
     4381 tcgccgccaa gaataacgca gttgcttcta tgttcgacgg tatcggcatg ggacttggtt
     4441 tcaccattgc cctgacattg ctgggggctg tccgtgaatt tctgggaacc ggtaagattt
     4501 tcgatctgac catcatgccg gaagaatatg gaatgttggt atttgtattg gctccgggtg
     4561 ctttcatcgc tttgggatac ctcattgcgc tgattaacag tttcaagaaa gcctaattca
     4621 attaaataag aaaagaatat ggaatatata ttgatattta tttcggcaat ctttgtaaac
     4681 aacatcgtgt tgtcgcagtt cttgggtatc tgtccgttcc taggcgtatc taagaaagta
     4741 gagactgcga tgggtatgag cgctgcggtt gctttcgtgt tgaccatcgc taccatcgtt
     4801 accttcctga ttcagaagtt tgtattggat gttttcgggc tgggatattt gcagacgatt
     4861 acgttcattc tggtcattgc cggattggtg cagatggtgg aaatcattct gaaaaaagta
     4921 tcgcctgctc tgtatcaggc tttgggcgtg ttcttgcctt tgattacaac caactgttgt
     4981 attcttggtg tggctatcct ggtgattcag aaagactacg acctgctgac aggtgttgtg
     5041 tacgcgtttt ctacggccat cggtttcggt ctggcactgg tgctttttgc cggattgcgc
     5101 gaacagatga gcctcgtgaa agtacctaaa ggaatgcaag gcactccgat tgccttgatt
     5161 accgccggtt tgcttgctat ggcattcatg ggattctccg gcgtggtgta aggatttaca
     5221 gttgataatt aaatagggga ttggaagctc tgctgtatgg cgtcatacag ctttgagttt
     5281 ccaattcttt tttatacctg attgccaccc aatcgtacct aaattacttt tcagcaaata
     5341 aaattgtggc aaattattgc tattccattt tatttccata catttgtaac tcaaacaatg
     5401 ataagccgag aaactaacca tttttataaa gtatatgaaa gaaagaattt tagtaacagg
     5461 cgggacagga tacatagggt ctcatactgt tgtagaacta caaaacagtg gatatgaagt
     5521 aatcatcatc gataatttat caaattcaag tgctgatgtt gttgacaata tagagaaagt
     5581 ttccggtatt cgcccagttt ttgaaaagct ggattgtctg gactttgctg gtcttgatgc
     5641 agtatttaca aaatataaag gaattaaggc gatcattcac tttgcagcga gcaaagcagt
     5701 aggagaatcg gtacagaaac cgttgcttta ctaccgtaat aacctggttt ctttgattaa
     5761 ccttctcgaa ctgatgccaa aacatggagt agaaggtatt gtgttctctt cttcctgtac
     5821 agtatacggc cagccggatg aattgccggt aacagaaaag gctccgatta agaaagcgga
     5881 atcgccatac ggaaatacga aacagattaa tgaagagatt attcgtgata cggtagcttc
     5941 aggtgctccg atcaatgcga ttatgctgcg ctatttcaat ccgattggtg cgcatcctac
     6001 ggcattgctg ggtgaactgc ctaatggggt tcctcaaaac ctgattccat atctgaccca
     6061 aaccgccatc ggcatccgtg agaaactaag tgtgtttggt gatgattatg atacaccgga
     6121 cggttcttgt atccgtgact ttatcaatgt tgttgacttg gctaaagccc acgtgatcgc
     6181 tatccgtcgt atcttggaaa agacacaaaa agaaaaagtg gaagtgttca atatcggtac
     6241 aggacgtggc gtttctgtat tggaattaat aaatggcttt gaaagagcca ccggcgtaaa
     6301 attgaattat cagattgtcg gacgtcgtgc aggcgacatt gaaaaagttt gggcgaatcc
     6361 ggatttcgca aaccaggaac tgggttggaa ggctgtagaa actttggaag atactttacg
     6421 ttctgcatgg aactggcagc tgaaactccg tgaaagaggg attcaataaa agagatttgt
     6481 tttaaaataa acataaaaga ttaaacaaat cgtgcatgcg atttgtttat ctgatgctaa
     6541 tcgacctgaa gctgtttatg agtatgcgaa tatacgtaaa tagtacttat gcctccccgg
     6601 catagacagg aaagattgca tagtagtttt gtcgtgtttt attttgtgtt tgtgttgtga
     6661 cggtactacg acgtgagtcg tggtaccgtt ttttgttcgc ccatactggg cgaacaaaac
     6721 tatgtttata gctttccttt gaaacagaaa acgtcgcttt ctcctattgt ttccggtaaa
     6781 gaagttccgg gggcgaacag tccgaacact gaagagccgg agccgctcat ggaggcgtag
     6841 atcgctcctt gatgatagag ttctctttta atttccccaa taacgggatg ttgcgggaat
     6901 acacttgctt caaaatcatt gattaggata tccttccatt ctgcaactgg acgcaggatt
     6961 gcctctttga ccggatattc cggacggtgg ggatgaatat ttgaaaaagc ttcccgggta
     7021 gaaacgaaaa cgttcggttt gacaatcatg atttggtaac cgcttaatga aagctcgatt
     7081 ggtgagaaca ggtttccgat tccttcggca taggtcggct tgtttttaat aaagaaagca
     7141 cagtccgctc ccaaagtggc ggcatatacc tccagctgtt cttcggataa ttccagctga
     7201 aaatgatcgt tgagcaactt tagcataaaa gcggcatcgg atgaaccgcc ccccagtccg
     7261 gctcccgagg gaatatgctt atacaaatga atttcgacag ggggaagatg aaactcctta
     7321 tccagcaatg aataggcctt tgccaccagg ttgtcttccg gattgccggc tatctccatg
     7381 ccatactggt ggagggtaat cttcttttct gtttcagaag aagtacggat ttcgagagcg
     7441 tcttcgaggg ctaccggata gaaaacggtt tccagattgt gatatccgtc cgggcgtttt
     7501 tccgtgatgg aaagtcccag gtttattttg atattaggaa aagcgagcat ttgatttatg
     7561 atttatgaat tatgatttat gggttgctaa attgcgatgt tgtggcaaag atactaaaat
     7621 cttcattttt ctttattcat tcttcattat tatattctat ctttgtcgtt ccgattggaa
     7681 aaagcctgcc aatggaagcc atccaatcat aaatcataaa tcaaaattca taaatcataa
     7741 aagtttttca tggccgaaca gaaaagaaat acccgcaata caaagtctac taaggtacaa
     7801 ccggtaaatg attatggtcg tattcagccg caggcacctg aactggaaga agcagttctg
     7861 ggagctttga tgattgaaaa ggatgcttac tcattggtga gtgagattct tcgtcccgaa
     7921 tctttttacg aacgccggca tcagttgatt tattctgcta tcaccgatct tgcggtgaat
     7981 cagaaaccgg tggatattct gactgtaaag gaacaactta gcaaacgcgg agaactggaa
     8041 gaggtgggag gcccgttcta tattactcaa ttgagtagta aggtggcttc atcagcgcat
     8101 attgagtatc acgcccgtat tattgcacag aaatctttgg cgcgtgagtt gattacgttt
     8161 acgagcaata tccagagtaa agcgtttgat gaaacgctgg atgtggacga cttgatgcag
     8221 gaagcggaag gtaaactttt tgagatttcg cagcagaaca tgaaaaagga ttatacgcag
     8281 atcaatccgg tgattgacga agcctataag ctgattcaga aggctgcggc gcgaaccgac
     8341 ggtttgagtg gtcttgagag tggttttaca aagctcgaca agatgacttc cggttggcag
     8401 aattccgacc ttatcattat cgctgcacgt cctgcgatgg gtaagaccgc ctttgtcctt
     8461 tctatggcta agaatattgc tgtcgattat cggaacccgg tggcgttgtt ctctcttgaa
     8521 atgagtaacg ttcagttggt gaatcgtttg attgcgaatg tctgtgagat tccgagtgag
     8581 aagatcaaaa gtggacagtt ggcaaattat gaatggcagc aattggacta taaactgaag
     8641 aatctgatgg atgcaccgct ttacgtggat gatactccgt ctctgtctgt atttgaactt
     8701 cgaacgaaag cgcgtcgtct ggtacgtgaa catggagtga gaatcattat tattgactac
     8761 ctccagttga tgaatgcgag cggtatggcg tttggtagcc gtcaggaaga ggttagtacc
     8821 atttcccgtt cgttgaaagg actggcgaaa gagttgaata ttccgattat cgcactgtcg
     8881 cagttgaatc gtggtgtgga aagtcgtgaa ggtattgatg gtaaacgtcc gcagttgagt
     8941 gaccttcgtg aatcgggagc catcgagcag gatgccgata tggtgtgctt tatccaccgt
     9001 ccggaatact ataagattta tcaggatgat cgtggtaatg acttgcgtgg tatggcggag
     9061 attgtcatcg ccaagcatcg taatggtgcg gtaggcgagg tgttgctccg gtttaaggga
     9121 gaatttaccc gtttctccaa tccggaggac gatatggtta tcccgatgcc gggtgagcct
     9181 gccggggcta tgctaggatc gaagatgaat acaggtgatg ccggctcgat gcctcctcct
     9241 cccgcgcctg attttgcacc gcagacagcg aatccgttcg gagcaccggg ggatggacct
     9301 ttgccgttct agttgcgtcc tctgtggtga aataacgcgc aattttttat caaaccttct
     9361 cggtcaaccg aaaaatctta ttaactttgc gaatcttttt gagaaacaat aaaaaattaa
     9421 gtatatgaat atctcttata actggctgaa agagtatgtc aacttcgacc tgacgcccga
     9481 tgaaacggct gctgcgttga cttctatcgg cttggaaaca ggtggtgtag aagaagtgca
     9541 aaccattaaa ggtggtttgg aaggacttgt gatcggtgaa gtgctgacct gcacggaaca
     9601 tcctaattct gaccatttgc atattactac tgttaatctg ggagacggtg aaccggtaca
     9661 gattgtttgt ggtgccccga atgtggctgc cggacagaaa gtggtggtag ctactttagg
     9721 tacgaaactt tatgacggtg acgaatgttt taccatcaag aaatcaaaaa tccgtggggt
     9781 agaatctaca ggtatgattt gtgccgaaga cgaaattggg atcggtacgg atcatgcagg
     9841 tatcatcgta ttgccggaaa ctgctgttcc gggtacgctt gccaaggatt attataatat
     9901 caagagcgat tatgtactgg aagtggatat cacgcctaac cgtgcggatg cctgctctca
     9961 ctatggggta gctcgtgacc tgtatgctta tctgattcag aacggtcgtc aggcaacttt
    10021 acaacgcccg tcagtggatg gctttaaagt ggaaaaccat gacttgaata tcgaagtgaa
    10081 ggttgaaaac agcgaagctt gtccgcatta tgccggtgtt atcgtgaaag gtgtaacggt
    10141 gaaggagagt ccggaatggc tgcaaaacaa attgcgcctg atcggtgtgc gccctattaa
    10201 taatgtagtg gatattacga actatatcgt tcatgctttc ggtcagccgt tgcattgctt
    10261 cgatgccgga aagattaaag gcaatgaagt gattgtgaaa acaatgcccg aaggtactcc
    10321 gttcgttacg ttggatgaag tggagcgtaa gttgaacgaa cgcgacctga tgatttgcaa
    10381 caaggaagag gccatgtgta ttgccggcgt attcggcgga ctggactccg gttctacgga
    10441 agccacgaca gacgtattca tcgaaagtgc ttatttccat cctacatggg tgcgtaagac
    10501 ggctcgtcgt catggcttga atacggatgc ttctttccgt ttcgaacgtg gtatcgatcc
    10561 gaacggcgtg atttattgcc tgaaactggc tgctttgatg gtgaaagaac tggctggcgg
    10621 tacgatttct tctgaaataa aagatgtatt cactacccct gcacaggatt ttatcgtcga
    10681 tcttgcttac ggaaaagtac attctttggt aggtaaagtg attccggtag agacaatcaa
    10741 gagcattgtg accagcttgg aaatgaagat taccaatgaa acggcagaag gactgacatt
    10801 ggctgttcct ccttatcgtg tagacgtgca acgtgattgc gatgtgattg aagatattct
    10861 tcgcatctat ggatataata atgtggaaat tccgactacg ttgaactcca gtctgactac
    10921 aaagggtgag cacgacaagt cgaataaatt gcagaatctg attgcagaac aactggtggg
    10981 ctgtggattc aatgaaattc tgaacaactc actgactcgt gctgcttatt atgatgggtt
    11041 ggaggcttat ccgtccaatc acctggtgat gttgctcaat ccgttgagtg ctgatttgaa
    11101 cgctatgcgt cagactttgc tgttcggcgg actggaaagc attgctcata acgccaatcg
    11161 taagaacgct gatctgaaat tcttcgaatt cggtaactgt tattatttca atgctgacaa
    11221 gaagaacgaa gagaaggtac tggctcctta ttcggaagat tatcacctgg gcttgtgggt
    11281 aaccggtaag aaggtttcca attcatgggc gcatgcggat gaaaatagtt cggtgtatga
    11341 attgaaagcg tacgtagaaa atatattaaa acgtctggga ctggatttgc acaatctggt
    11401 tgtaggtaat ctgacagacg atgtttttgc tgccgcactc tctgtcaaca caaagggcgg
    11461 aaaacgtctt gcttctttcg gtattgtaac taagaagctg ttgaaagcat ttgatatcga
    11521 caatgaagta tattacgccg acttgaactg gaaggaattg atgaaagcca tccgttctgt
    11581 gaagatcagc tacaaggaaa tttccaaatt ccctgctgtg aaacgcgact tggcattgtt
    11641 gcttgataag aatatacaat ttgccgaaat cgaaaagatt gcatacgaaa cagagaagaa
    11701 gctgttgaaa gaagtggaac tcttcgatgt atatgaaggt aagaacctcg aagcgggtaa
    11761 gaagtcgtat gcggtgagct tcctgcttca ggatgaaaac cagactttga atgataagat
    11821 gattgataag atcatgtcga aactggtgaa gaacctggaa gataaactgg gtgccaaact
    11881 tagataaact taaaattgtc attattaaaa atataaacca atgggaagag catttgaata
    11941 tagaaaggcc gctaaactga aaagatgggg ccacatggct aaaactttta caagactggg
    12001 taaacaaatc gctatcgctg taaaggcagg cggtccggaa cctgaaaaca acccgacgct
    12061 gcgttcggtg atcgctactt gtaagcgtga aaacatgccg aaggataaca ttgaacgtgc
    12121 tatcaaaaac gcaatgggta aagaccagag cgactacaag agcatgactt atgaaggata
    12181 cggccctcac ggtattgctg tgtttgtaga cacattgaca gacaacacaa ctcgtacggt
    12241 ggctgacgtt cgttcggtat tcaataagtt cggtggcaat ctgggtacaa tgggttctct
    12301 tgcgttcctt ttcgaccaca aatgtgtgtt cactttcaag aagaaagacg gattggatat
    12361 ggaagaactg attctcgatc tgatcgacta tgacgtggaa gatgaatatg aagaagatga
    12421 tgaagaggga acaattacta tctatggtaa tcctaagagc tacgccgcta ttcagaagca
    12481 tttggaagaa tgtggctttg aagatgtcgg tggagacttc acttatatcc cgaacgactt
    12541 gaaagaggtt actccggaac aacgcgaaac attggataag atgatcgaac gtctggaaga
    12601 atttgatgac gtgcagactg tctataccaa catgcaaccg gaagagggtg aagagtaaag
    12661 taaggttatg gaatatgttt ataagaccca gggaacttgc agcacgaata tcgaactgaa
    12721 tgtggaagat ggagtggtga aggaagttgc tttctgggga ggatgtaatg gtaaccttca
    12781 aggtatttcc cgccttgtga gaggaatgaa ggtggaggag gtgatcgcaa aacttgaagg
    12841 agtgcgttgt ggtggcaggc cgacatcttg tcccgatcaa ttatgtcatg cattgcatga
    12901 gatgggatat tgattgatct tcatttatgt aaattatata ttgatttgtg acctctggca
    12961 attggtttgt cggaggtcat tttttttgca gaaagtcctt atttcctttt ctcgagtagt
    13021 ccttactcaa tccttttata ataatgtcct cataattagt gtatcatctg tgtccatagg
    13081 tcatctactt attggtcggt attttgaact aaaattgatt ctcactcgtt atttataagt
    13141 atatttgtac tggataaact attatgcaaa aatgaagaat atttttcaag acttaagacg
    13201 caaagatcat aaacgctatc tgggtggact ggatgttttt aaatatattg gtccggggct
    13261 actggttact gtaggattta ttgatccggg aaactgggct tctaatttcg ccgccggttc
    13321 cgaattcggc tattccttgc tttgggtggt taccttgtct actatcatgc tgattgtcct
    13381 tcagcacaat gttgctcact tgggaatcgt taccggactt tgcctttcgg aggcggccac
    13441 taagtacact cctaaatggg tgtcacgacc tattcttggt acagcagtac tggcgtcgat
    13501 ctctacttcc ctggcggaaa ttctgggagg tgccatcgcg ttggaaatgt tattggatat
    13561 tcctattata tggggagctg tattgactac gctttttgtc tccatcatgc ttttcactaa
    13621 ttcgtataaa aagatagaac gttccatcat tgcgttcgtt tctgttatcg ggctttcatt
    13681 tatttatgag ttgtttctgg tggaaataga ctggccggct gcaacggcgg ggtgggtgac
    13741 tccttctttc ccgaaaggta gtatgctgat tatcatgagt gtgttgggag cggtagtgat
    13801 gcctcacaat ctgttccttc attcggaggt gatacagagt cacgagtaca ataagaaaga
    13861 tgatgcttct attaagaagg tattgaaata tgagttgttt gacactcttt tctcaatgat
    13921 tgttggttgg gcgattaaca gtgccatgat tctgctggcg gccgccactt tctttaagag
    13981 cggtattcag gtagaggaac tgcaacaggc taagtctttg ctcgaacctt tattgggaag
    14041 taatgcggca attgtatttg cattggcatt gctgatggcg ggcatttcgt caactattac
    14101 gagcggaatg gcggcaggtt ctatttttgc aggtattttc ggcgagtctt atcatatcaa
    14161 ggacagtcac tcgcaggtgg gagttctctt gtctttggga attgccttat tgctgatttt
    14221 ctttattgga gatccgttta aaggattgat tatttcgcag atggtactta gtattcaatt
    14281 gcctttcacc gtgttcttac aggtgggact gacgtcttcc cgaaaggtga tgggcgatta
    14341 tgtcaatagt cgttggagta cgttcgtgtt gtactcgatt gctattatcg tttcggtact
    14401 gaacattatg cttttgtttt cataaaatga acatgaactt ataaatatag aatgatgaaa
    14461 attattactt ataacgtgaa cggactacgt gctgccgtat ctaaagggtt accggaatgg
    14521 ttggcacagg agaatcctga tattctttgt ctgcaagaga cgaaactgca accggaccaa
    14581 tatccgggag aagtgtttga agcattgggc tacaagtctt atttatactc ggcgcagaag
    14641 aagggataca gtggagtggc tatacttacc aagcgggaac cggaccatgt ggaatatggg
    14701 atgggaatgg aagcatacga taatgaagga cgtttcattc gtgcggactt cggagacttg
    14761 tcggtagtca gcgtttacca tccttcggga acgagcggag atgaacgcca ggcctttaaa
    14821 atggtctggt tggaagattt ccagaaatat gtgatggagt tgcagaagtc tcgtcccaac
    14881 ttgattcttt gcggcgatta taatatctgt cacgagccga ttgatattca tgaccctgtc
    14941 cggaacgcga ccaacagcgg tttccttcct gaagaacggg aatggatgac gcgtttcctg
    15001 tctgcgggat atgtggactc tttccgtacg ctttgtccgg agaaacagga atatacctgg
    15061 tggagctatc gttttaattc gcgtgccaag aataaaggct ggagaattga ttattgtatg
    15121 gtcagcgagc cggtacgccc gctgttgaaa cgggcgtata tcttgaatga ggccgtacat
    15181 tccgaccatt gtccgatggc tctggaaata t
//
