LOCUS       c00115_gnlPro..        12815 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPLCELAE_115.
ACCESSION   c00115_gnlPro..
VERSION     c00115_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:42:20
            Original ID  :: gnl|Prokka|IPLCELAE_115
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12815
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12815
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[43:2815]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      44..2815
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12815
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12815
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             44..2023
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 202.3; E-value:
                     4.6e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_1"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.5e-62, bitscore:
                     202.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.6e-37,
                     bitscore: 117.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLYKEPLVYEAIKVQTRNYKS"
     CDS             2060..2815
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg115_2"
                     /sec_met_domain="Fer4_7 (E-value: 3.5e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIAKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(3440..4279)
                     /locus_tag="ctg115_3"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQKCEENLILF
                     LMKGEILVNSKEYAGTMLKGGEFILQAIGSMFEMLVMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSPPLIYTPLKIIPELQYFLNGSITYLKGDKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYVNSFQYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSKYSISEICYKYGFESLPHFSNFCKKSFGASPRNLRRQDIS"
     CDS             complement(4544..5509)
                     /locus_tag="ctg115_4"
                     /transl_table=11
                     /translation="MKKILLAVTAALAITGCSQNEEFEAPSQKAEINFNTAVTRATELD
                     IDGLKSSGFQVYAYNTKAEEMSATVTLSTPWINGSATYSDSKWTVSGGPYYWPLAENLQ
                     FFAYSPKDGVTYTAPNGTTDKGYPKFTYTVGNTAALQKDLVIASVANAQKKTNEAATDV
                     SLTFKHALTQVNIEVTKEAGYTYTISKVELTGIKGSGTFTYAGVNAGTWTAGTETSVSY
                     AYELGAFSDDKTAVKAGNALMLIPQALTDAKISIEYTVEKDGSKIAENSKEVSLTSTAA
                     WAFGKKILYKLTLPIGAQEVGITATVTGWDAEDPVTPTVD"
     CDS             complement(5564..6523)
                     /locus_tag="ctg115_5"
                     /transl_table=11
                     /translation="MLTGCSRRDILDDYPVSGVDIKLDWDGMTDQLPEGVRVIFYPKNG
                     EGRKVDKYLSVRGGEMKVPPGRYSVVTMGYNFNSDRIRIRGEESYESIEAYTEYCNDLG
                     IAGMEKMVWSPDSLYVLNIDELKIEKSEEVLHLDWKMESVVKKYFFAVEAKGLEYVATV
                     VGSIDGLSDCYCIGKGRGVCSSQPIYFEVKKGDNKVTASFTAFKQVKEMTMPTRMSISE
                     RETSSEKDAIILILKFIKTDNTVQEATIDVTEIIGTLENAGTGEDGKPTPPPEIELPPD
                     DKIEVDKPETPPNPDGGGGMGGNVDGWGPEDNVELPVK"
     CDS             complement(6581..7858)
                     /locus_tag="ctg115_6"
                     /transl_table=11
                     /translation="MKHGIYILAILMVLLGLPESGYASIPFFAVANDTIRRVMIYFDAN
                     DAGVNSCYKSNNQAIATLDSLLSGNLGTKYVTALNVKTFVSPDGNESYNRGLAARRNDS
                     IKEFLQRYNSDVSVDKIHFFSEGEDWSEFRKLVASDSNLPDREEVLMLIDYHKNDIDKR
                     KRLLRKLNRGIAYRYIVHNIFPELRRSVITIVGETSKLGKEAFEPVSSVFGLFVSNQEE
                     ALPKDQPDKSVGESEEKQACEVDISETEGPVKSQTVLAVKNNLLYDLALAPNIEVEIPI
                     GKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRCWLGNRQKRNRLTGHFIGLYAEGGI
                     YDFQLRGDGYQGKYYGAAGVTYGYARQLARHFSLEFSLGIGYLTTEYKKYTPYEGDIIW
                     TNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             8008..8220
                     /locus_tag="ctg115_7"
                     /transl_table=11
                     /translation="MSLVTHLRDNTVLLFRLHQQFTFIGSSDKRLFHIHMDAKLHRLHT
                     NREIAMIGSRQEFSTRYFIPTQKLH"
     CDS             complement(8404..8790)
                     /locus_tag="ctg115_8"
                     /transl_table=11
                     /translation="MQSISNADILDMLLFVEERINTTIERCGSVISVNDFLASPDKMDI
                     FDATCMRLQTIGETVKNIDNLTNHELLINYAGTPWRSIIGLRNIISHEYLSIDPEEIFK
                     IVKVHLPGLLLAIQQIRNDIAASI"
     CDS             complement(8774..9067)
                     /locus_tag="ctg115_9"
                     /transl_table=11
                     /translation="LKTKDEIIAILRNFKEEFGERYGIEKLGLFGSVARGEQKEDSDID
                     ICVKLQDPDYFTRMEIKESLEERFNAKVDVVSLTAIMRSLFRNHIEKDAIYI"
     CDS             complement(9283..10533)
                     /locus_tag="ctg115_10"
                     /transl_table=11
                     /translation="MMVISMTAFAQEDVFSGDWLGANKEGDLKVAFTLNCDGNWQLNPY
                     NENARCNGFMEVNMLEPGGRESLMATYEFYVESMNGNELTLSFVGGRPEVDAGISGQCK
                     VVYKDDKLSFSGLDKGGKDAAFNGLTLVKSGSGADAIADAAADDGVPLGVKILAVLQLI
                     LYIAVVLFIVGHMFFVWYKGARYKEVFTVEGMLNKRLAAGMPEKMTDEEITEAWKLMDE
                     AFATWTVIEKTDDDEFRKPTKMKQIKKSVLLIDQVIGMCPTDADVIERLNSLTDVINSG
                     EERHFDGSRKLIWLGVIVGILMYWMMGVGMMFSTLIATGLYVVASRTPQFLIDKRALRG
                     GGNIHNGIFAGVFGLLAGAQTVRTIYKFNDGHKEYSDDHSQHWIALAIGLVVLFVLAMM
                     MAFWALLNYLRNYVLYF"
     CDS             complement(10582..12156)
                     /locus_tag="ctg115_11"
                     /transl_table=11
                     /translation="MRKNRIRILSMVVFSLCLPFSLFAQIDKDMKEFDDFVKQQQKEFD
                     DFVSEQNKEFAEFLKETWKEYDLQKPVARPQRPEPVKPVSFDHKKPATKPQEVKVGEVT
                     RLPIPTVTPSATFSPSKGKTQVPVVPGGKDVAVEPEKDFAVLPEIKPEVKPEETVPAKR
                     SLSGVEFSFYSKDCVVNASLKNRLTLKGIAEKDISAGWETLSRSNYQPLIDDCLAFKKD
                     NALNDYGYLLLTRKVATELCGSTHSDEIALMQMFLLSQSGYRVKVARMDNRLTLFYASG
                     NMIYATCFITLNGVNYYRFDTTPNKTNSIYTYNRDFANAKNPVNMNITTPQPFSGTYVE
                     KTLQAKAYPSVKVCSKVNSGLISFYKDYPQCDFSVYVGAPVSQEVQQTVLPSLQAAIQG
                     KKQSEAANILINFVQTAFDYKTDGDQFGYEKPFFVDELFYYPYSDCEDRAVLYSYLVRT
                     LMGLDVVLLEYPNHMATAVCFDENIDGDYITVSGKKYIICDPTYIGASIGLAMPQFKNV
                     AAKVLKY"
ORIGIN
        1 tgctaaatag taaattgtaa atgattaaat tgtaaataat attatgatca agatagattc
       61 aaaaattcca gaaggcccgg tggctgagaa atggaccaac tataaagctc accagaaatt
      121 ggtgaacccc gctaataaac gtcgtttgga catcatcgtt gtgggtacgg gtctggcagg
      181 tgcttctgcc gctgcttcac ttggtgaaat gggtttcaga gtattcaatt tctgtattca
      241 ggattctccc cgtcgtgcac actctatcgc tgcacagggt ggtatcaatg ctgcaaagaa
      301 ttatcaaaat gatggtgact cggtttaccg tctgttctac gatactgtaa aaggtggcga
      361 ctatcgtgcc cgtgaagcaa acgtatatcg tttggctgaa gtgtctaacg ctatcatcga
      421 ccaatgtgta gcgcaaggtg ttcctttcgc tcgcgaatat ggcggtacac tagataaccg
      481 ttctttcggt ggcgcacagg tatcccgtac tttctacgct aaaggccaga ctggtcagca
      541 gttgctgctg ggtgcttact ctgcattgag ccgtcaggta aacgtaggta ctgttaaact
      601 gtatacccgc tacgaaatgc aggatgttgt catcgttgac ggacgtgccc gcggtatcat
      661 cgcaaaaaat cttgtaacag gcgaattgga acgtttcgcc gctcacgctg tagtaatcgc
      721 tactggtggt tatggtaacg cttacttcct gtctactaac gctatgggtt gtaactgtac
      781 agctgctatc tcttgctacc gcaagggtgc tgtattcgca aatcctgcat acgttcagat
      841 tcacccgact tgtattccgg tacatggtga caagcagtct aagctgactt tgatgtctga
      901 atctctccgt aacgacggtc gtatctgggt tccgaagaag aaagaagatg ctgtaaaact
      961 ccagaaaggc gaaatcaaag gaagtgatat tccggaagaa gaccgcgact attatttgga
     1021 acgccgctat ccggcattcg gtaacctggt tccgcgtgac gttgccagcc gtgccgctaa
     1081 agaacgttgc gacgctggtt tcggtgtaaa caacacaggt ttggccgtat tcctcgactt
     1141 ctctgaagct atcaaccgtt tgggtatcga cgttgttctt caacgttatg gtaacctctt
     1201 cgatatgtac gaagaaatca ctgatgttaa tccgggcgaa ctggctaaag aaatcagtgg
     1261 tgtgaaatat tataacccga tgatgattta tccggctatc cactatacaa tgggtggtat
     1321 ctgggtagac tacgaactgc aaaccactat caagggtctg ttcgctatcg gtgaatgtaa
     1381 cttctccgac catggtgcaa accgcctcgg tgcttctgca ttgatgcaag gtttggctga
     1441 cggttacttc gtattgcctt acactatcca gaactatctg gcagaccaga tcactgttcc
     1501 tcgtttctct accgatcttc ctgaatttgc tgaagctgaa aaagcagttc aagctaagat
     1561 tgacaagttc atgagcatcc agggtaaaga atctgttgat tctatccaca agaaactggg
     1621 tcatgtcatg tgggaatatg taggtatggg acgtacggca gaaggcctga agaaaggtat
     1681 cgccgaactg aaagaaatcc gcaaggaatt cgaaacgaac ttgtttatcc ccggttctaa
     1741 ggaaggtatg aacgtagagc ttgacaaagc aatccgtctg tacgacttca tcactatggg
     1801 tgagcttgtt gcttacgatg cattgaaccg taacgaaagt tgtggtggtc acttccgtga
     1861 agaataccag actgaagaag gagaagctaa acgtgatgac gaaaacttct tctatgtagc
     1921 atgttgggaa tatcaaggtg acgatgaaaa agctccggta ttatacaaag agccgttggt
     1981 atacgaagct atcaaggttc aaacccgtaa ctacaagagc taatcggtga agttaaacat
     2041 ttaaaagaat tagaagaaaa tggataaaaa tatatcattt acactgaagg tatggcgcca
     2101 agctggtccg aaggctaaag gtgcttttga aacctaccaa atgaaagata tccctggcga
     2161 tacttccttc ctcgaaatgc tggatattct gaacgaacag ctcatcagcg aaagaaaaga
     2221 accggtagta ttcgaccatg actgccgcga aggtatttgc ggtatgtgtt ctctttacat
     2281 caacggacac ccgcacggtc ctgcaacagg tgctactact tgccaaatct atatgcgtcg
     2341 tttcaacgac ggtgatacca tcactgttga accttggcgt tcggctggtt tccctgtcat
     2401 caaggatttg atggtagacc gtactgcata cgacaagatt atgcaagctg gtggttatgt
     2461 aagcgtacgc acaggtgctc cgcaggatgc taacgctatc ctgattgcga aacctatcgc
     2521 tgacgaagct atggatgctg cttcttgtat cggttgcggt gcttgtgtag ctgcatgtaa
     2581 gaatggttct gctatgttgt tcgtttctgc aaaagtcagc cagttgaact tgctgccgca
     2641 aggtaaaccg gaagctttgc gtcgggcaaa agctatgttg tcaaagatgg acgaactggg
     2701 attcggtaac tgtacaaaca ctcgtgcttg tgaagctgaa tgtccgaaga acatctctat
     2761 cagcaacatc gcccgcttga accgcgactt catcatcgca aaattaaaag actagaaatt
     2821 gctagatttc aatagcgaga gcttaatttg attaatgaca gaatcccctg ccggctagtc
     2881 cgacagggga tttctttatg tatgagtaga tcacaattat tattaatacg gatcagtaac
     2941 atgaactttt aattcataag tttcaccgat ttcaccttat agccgaaact gttatgaatg
     3001 agagaattac gggtgaaagc gaggattgaa ataaggtaaa atcattcgtt atcgctttca
     3061 cctgtcttat taaaatatcc cttgagctaa aacaattatc attatagcta atccggatat
     3121 gcttatagca aatccgcttt caggtgttaa tgagtgaact gtgcggatat aacactttgg
     3181 ccgccaggtc ttaacacctt agttctcatg tgttaatact tgagttgttg catctatata
     3241 tccagcatct tggagctata tatccagcat cttggatcta tatgtccaac agtcggtatg
     3301 aataaactca ataggtgaaa ccggaaaggt tcagtttcac ctgaatttct tccttgcttt
     3361 cacccgctgt taccttattc atcggcattt agagaattgg gtgaaaccgg tgaaccgcaa
     3421 ttatcttaca tagttgcatt tatgaaatgt cttgcctacg taaattacgt ggagaggcac
     3481 caaaagattt cttgcagaaa ttagaaaaat ggggtaaaga ttcaaagcca tatttatagc
     3541 atatctccga aatgctatat ttagagttat tcaagtcgtc gagaatacct tctttacgcc
     3601 gtgccagcat ccattcataa acaggttcat gaaagacgtt attgaaaata cgacggaatg
     3661 tactaagagt atatccgcct aattgagcga gttcttctac tgtctttact ttcttatagt
     3721 tttgaataac gaagtattgg aaactgttta cgtacttgga aagtggatgc accaagctcg
     3781 aaagatcata atcagaataa tagtatccca acacaaacgc taattctttt cgtttcagag
     3841 atagcaaatc ccgacagact ttatcccctt tcagataagt gatagaccca ttaaggaaat
     3901 attgcaattc aggtattatt tttaatggag tataaataag tggaggagat acttccttca
     3961 tgatatgatt aaaacggaaa tcacaaaaca gttccggctg aataaaacga taataaatgc
     4021 actcacattc agtcataaca agcatctcaa acatagaacc aatggcctga aggataaatt
     4081 cacctccctt aagcatggtc cctgcatatt ccttactatt gaccagtatt tctcccttca
     4141 tcaaaaaaag gataagattt tcttcacact tttgagccgg tttatgaaaa ccacgctgat
     4201 aaatcacatg agtaatggca ttactcaccg cttttggaca tatttggcaa tcccaagttc
     4261 cttgacaaat agatggcata cgctggctgt gtttgcattt attttacgtt aacagcaaaa
     4321 tatatgaaat ttttcatatt gccataaaaa aagagagaaa agtgaaaaag aggttaggta
     4381 agagaaaaaa ggtatccact acaaaaatgt aagtaacata tagaattaaa attcccagtc
     4441 tttttctgga gaaactaggc tatattttct atcataattc caaaacacaa gaagaaccga
     4501 tgtaacatac aaattacatc ggttccatag atttaatctt gtgttagtca acagttggag
     4561 ttacaggatc ttcagcatcc caaccagtaa cagttgcagt gataccaact tcttgagcac
     4621 caataggcaa tgttagttta tatagtattt tctttccaaa cgcccatgca gcagtacttg
     4681 tcaaagatac ttccttacta ttttcagcaa tcttacttcc atctttctct acggtatatt
     4741 ctatagatat ttttgcatca gtaagagctt gcggtattaa catcaacgca ttacctgctt
     4801 ttacagctgt cttatcatct gaaaaagccc caagttcata tgcataagag acacttgtct
     4861 ctgtacctgc agtccaagtc cctgcgttaa cacctgcata tgtaaatgtt ccacttccct
     4921 taattccagt caattccact ttagatatag tataggtata accagcctct tttgtcacct
     4981 cgatatttac ttgagtcaat gcatgtttaa aagttaaaga aacatctgtt gctgcttcat
     5041 ttgtcttctt ttgagcattt gccacagatg caatcactaa atccttttga agggcagctg
     5101 tatttcccac tgtataagta aacttaggat atcctttatc agtagtacca ttcggagctg
     5161 tatatgtaac tccgtctttt ggagagtatg caaagaattg cagattttct gcaagaggcc
     5221 aataatatgg acctccagat accgtccatt tagaatccga ataagtagca gaaccattta
     5281 tccatggtgt cgaaagagtc accgtagcac tcatctcctc tgccttcgta ttatacgcgt
     5341 aaacctgaaa gccagaactc tttaaaccgt ctatatccag ttcagtagct ctagttaccg
     5401 ccgtattaaa attaatttcg gccttctgtg aaggggcttc aaactcttca ttctgtgagc
     5461 aacccgtaat tgccaaagca gctgttactg ccaataaaat cttcttcata actgtatttt
     5521 tttaagttta taatattgtt atattttgtt tatagcatct atttcatttc acgggtaact
     5581 caacattatc ttcgggtccc catccatcaa cattgccacc cattcctcca cctccatcag
     5641 gattcggtgg tgtttccggc ttatcaactt caatcttatc atcaggcggt aactcaatct
     5701 ccggtggtgg ggttggtttt ccatcttccc ctgttccagc attttcaagt gtacctatta
     5761 tttcagtaac atcaattgtt gcttcctgaa ctgtattatc tgttttgata aatttcaata
     5821 ttaatattat agcatctttc tcactagaag tttccctctc tgatattgac attcgcgtcg
     5881 gcattgtcat ttcctttact tgtttgaaag cggtgaaaga tgccgttacc ttattgtctc
     5941 ccttctttac ctcaaagtag ataggttgtg agctacacac tccacgacct ttgcctatac
     6001 agtaacaatc ggataatcca tcaatgctcc ctaccactgt tgcaacatac tccaaacctt
     6061 tagcctctac tgcaaaaaaa tatttcttca ctacagattc catcttccag tctaaatgaa
     6121 gcacttcttc actcttctct attttcagct catctatatt caatacatac aacgaatcgg
     6181 gtgaccaaac catcttttcc attcctgcaa tccccaaatc attgcaatat tctgtataag
     6241 cttctataga ttcataggac tcttctcctc taattcgtat acgatccgag ttaaagttat
     6301 aacccatagt tactaccgaa taccgtcccg gaggaacttt catttctcca cctcgtaccg
     6361 aaaggtattt atctactttc ctgccttctc cgttcttcgg ataaaaaatc acccgaactc
     6421 cctccggcag ttgatctgtc attccatccc aatccagctt tatatctacc ccacttacgg
     6481 gataatcatc caatatatcg cgacggctac acccggtcag catcagcagc gaggacaaaa
     6541 gcacaagaaa cctgtatctt gtatttcgca ttgcgccctc ctatctcttt gttgttatca
     6601 accataccaa agaaactttc gccttggtag ggccaataaa gttataacgc ccactgtttg
     6661 tccatataat atctccctca taaggagtat atttcttata ttctgttgtc aaatacccta
     6721 tgccaagact gaactctaga gaaaaatgcc gtgccaattg ccgtgcatat ccataagtca
     6781 ctccggcagc tccatagtac ttaccctgat acccatctcc acgtaactgg aaatcgtata
     6841 ttccaccttc agcataaagt cctataaaat gtccggtcag tcggttgcgt ttctgccggt
     6901 ttcccagcca acaacgtcct tccatccctc cagaaaggag ctgatagcag aaatcgtgtt
     6961 tactattcag ccaccacgga catttatatt cagtattcaa agaccacctc ttacctatcg
     7021 gaatttctac ttctatattc ggtgccaatg ccaaatcata taacagatta ttcttcactg
     7081 caagtacagt ttggcttttc accggccctt ctgtctccga tatatcgacc tcacaggcct
     7141 gtttttcttc actttctccc acagacttat caggttgatc tttcggaagc gcctcttcct
     7201 gatttgaaac aaacaacccg aagacagaag ataccggttc aaaagcctct ttacctaatt
     7261 tcgaagtttc tccaacaatc gtaataaccg atcgccgcag ttccggaaaa atattgtgaa
     7321 caatgtatcg gtaagcaatt ccccgattca attttcgcaa cagtcgcttc cgtttgtcga
     7381 tatcattctt atgataatca atcaacatca gcacttcttc ccgatccggc aagttggagt
     7441 cggatgccac caacttacga aactccgacc aatcctctcc ctctgaaaaa aaatgaatct
     7501 tatcaacact aacatccgaa ttataccgtt gtaagaattc ctttatcgaa tcatttcttc
     7561 gggcagccaa acctctatta taagactcat tgccatcagg agaaacaaaa gttttcacat
     7621 taagcgcagt tacatatttc gtacccaaat tcccggaaag caaagaatcc aaagttgcaa
     7681 ttgcctgatt attactttta taacatgaat tcactcccgc atcattcgca tcaaaatata
     7741 tcattacccg ccggattgta tcattcgcaa cagcgaaaaa tggaatcgaa gcatacccac
     7801 tttctggaag gcctaataaa accataagaa tagccaatat atagatacca tgtttcattg
     7861 tcgttcgttt ctgctgacaa atatagaagt tagaaaacaa accgaatcat acttttaaaa
     7921 caaaaatcaa gacatgaaag attctgtgaa acgattgaaa cgattttgca agttttgaga
     7981 gtttaaggtc aataataaac agaaagaatg tccttggtaa ctcatctgcg tgataacacc
     8041 gtacttctgt tccgcctgca tcagcagttc acattcatag gaagttctga caagcggctt
     8101 ttccacatac acatggatgc caagcttcat cgtctccata caaatcggga aatagctatg
     8161 atcgggagtc gccaagaatt ttctacgaga tattttatcc ccacccaaaa acttcattaa
     8221 agaacaacgg atcaattttg catcaagact tcttgtgacc acttcactca ccattgaaga
     8281 aatcatgtat caaagtgggt ttatgaatag atcacatttc tataagaagt ttacaaagcg
     8341 gataggagtg gcacctaaag actaccgttt gcataataaa aaaataggaa agctacaaag
     8401 gtctcatata ctagcagcaa tatcattcct gatctgctga attgcaagaa gcaatccagg
     8461 cagatgcact tttactattt taaaaatttc ttcggggtca atagataaat attcatgaga
     8521 aataatattg cgcagtccaa tgatgctcct ccatggagta ccggcataat ttatcaataa
     8581 ttcatgatta gtcagattat ctatattctt aacagtctca cctatggttt gcaaacgcat
     8641 acaagttgca tcaaaaatat ccatcttatc aggagaagct aagaaatcat ttacagaaat
     8701 gacactacca catctttcta tagttgtatt aatacgctct tctacaaaaa gaagcatatc
     8761 caatatgtca gcattagata tagattgcat ctttctctat atgattgcga aataaactac
     8821 gcataattgc ggttaaagac acgacatcca cttttgcatt aaaacgctct tctaatgact
     8881 cttttatttc cattcgagta aaataatccg gatcttgaag ctttacacaa atatcaatat
     8941 cactatcctc tttctgctca ccacgagcca cagaaccaaa aagtcctaac ttttcaattc
     9001 catatctctc cccaaattct tccttaaaat tccggagaat agcgattatt tcatcttttg
     9061 ttttcaactg acactattgt tataatgcaa atattaaaat taatattgga attagcaaat
     9121 tcttaatcat attttgtggt atcactaatt aaaaaaagat gcacaggtca tcaaattttc
     9181 atcgatcccc tgtacaccta ctactctaaa ttctacttca aaacataaat agcctaatta
     9241 tgctgccgaa tccattatta acaatcatgt tagttttatc catcaaaagt acagaacata
     9301 attacgtaaa tagttcagaa gtgcccagaa cgccatcatc attgccaata caaacaaaac
     9361 gacaagtccg attgccaaag caatccaatg ttgtgaatga tcatcagaat attctttatg
     9421 accatcatta aacttgtata ttgtccgcac tgtctgcgct cctgccaata acccgaacac
     9481 tccggcaaaa ataccattat gaatgtttcc accgccacga agtgcccgct tatcaattaa
     9541 gaattgaggc gtcctgctcg ctaccacata caaaccggta gctattaaag tagaaaacat
     9601 cataccgact cccatcatcc aatacatcaa gatacccaca atgacaccta accagattaa
     9661 tttcctggaa ccatcaaaat gacgttcttc accactatta atcacatcag tcaatgagtt
     9721 taagcgttct atgacatcag cgtcagtagg acacataccg ataacctgat caatcaaaag
     9781 aacagatttc ttaatttgct tcatctttgt cggctttctg aattcatcat catctgtttt
     9841 ttcaatcacc gtccaagtag cgaatgcctc atccatcagt ttccacgcct ccgttatctc
     9901 ttcatccgtc attttctccg gcattccggc tgcaaggcgt ttattcaaca ttccttctac
     9961 cgtaaaaacc tctttataac gtgcgccctt ataccataca aaaaacatat gccccacaat
    10021 aaataaaaca acggcaatat acaaaatcag ttggagaaca gccaatatct ttactcccaa
    10081 aggaactccg tcatccgccg cagcatcagc tattgcatca gctccactac cgctttttac
    10141 aagtgtcaat ccattaaagg cagcatcttt tccgccttta tcaagtccgg aaaacgacaa
    10201 cttatcatct ttataaacga ctttgcattg accggaaatc ccggcatcaa cctccggacg
    10261 tccgcctaca aaagaaagag tcagttcatt cccgttcata ctctcgacgt aaaactcata
    10321 agttgccatc aaagattccc ttccaccggg ttccagcata ttcacttcca taaatccatt
    10381 gcatctggca ttctcattat aaggattcaa ttgccaatta ccatcacaat tcaatgtgaa
    10441 cgcaaccttt aaatcgcctt ctttatttgc tcctagccag tcaccgctaa aaacatcttc
    10501 ctgcgcaaat gcagtcatcg aaataaccat cattacaatg gcacacaaat actttttaat
    10561 attcttcata atataataaa attaatattt caacactttg gctgccacgt tcttaaattg
    10621 cggcatagca agcccgatag aagctccaat ataagtcgga tcacaaatta tgtacttctt
    10681 tccgcttaca gttatataat ctccgtcaat gttttcatca aaacagaccg ctgttgccat
    10741 gtgattggga tattccaaca atacaacatc aagccccata agagtacgta ccaaataaga
    10801 gtataacaca gcacggtctt cgcaatcgga ataaggatag tagaacagct catccacaaa
    10861 gaaaggcttt tcataaccaa actggtcacc atctgtctta taatcaaaag ctgtctgcac
    10921 gaaattaatc agtatattag cggcttccga ttgttttttc ccttgtatgg cagcttgcaa
    10981 tgatggaagc accgtctgtt gtacttcctg actgacagga gctcccacat agacagaaaa
    11041 gtcacattgc ggataatcct tatagaaaga aataagtccc gaatttactt tcgagcagac
    11101 tttgacggat ggataagctt tcgcttgcaa cgttttctcc acgtaagttc ctgaaaaggg
    11161 ttggggagta gtgatattca tatttaccgg gttcttcgca ttggcgaaat cacggttgta
    11221 agtgtaaata gaattagttt tattcggggt agtatcaaac ctgtaatagt ttactccatt
    11281 caaagtaata aaacaggtag cataaatcat gttacccgaa gcatagaata aagtaaggcg
    11341 gttatccata cgcgccacct taaccctata tcccgattga gaaaggagaa acatttgcat
    11401 aagagctatt tcatcggaat gagtacttcc acatagttca gtagccactt tcctcgtcaa
    11461 cagcagataa ccatagtcat tcagggcatt atccttttta aaagccagac agtcgtctat
    11521 caaaggctga tagttgctac gcgataacgt ctcccatccg gcagaaatat ctttctctgc
    11581 aatccctttt aaagtgagcc ggttcttcaa tgaagcattg acaacacaat ctttactgta
    11641 gaacgaaaac tctacaccgg aaagtgagcg tttggccgga acggtttctt caggcttcac
    11701 ttccggtttt atttcaggga gcaccgcaaa atccttttcc ggttctacag ccacatcttt
    11761 acctcccggt acaaccggaa cctgtgtttt cccctttgaa ggagaaaatg tcgcacttgg
    11821 agtcactgtc ggaatgggga gtcgtgtcac ctcccctact ttaacctctt gcggttttgt
    11881 tgccggcttc ttatggtcaa agctgaccgg ttttacaggc tccggccttt gaggacgtgc
    11941 caccggcttc tgcaagtcat actctttcca ggtttctttc agaaattcgg caaattcctt
    12001 attctgttcg ctcacaaaat catcaaactc tttttgctgc tgcttcacaa aatcgtcaaa
    12061 ctccttcatg tctttatcta tttgcgcaaa aagactaaac ggcaaacaca atgaaaaaac
    12121 taccatagat agtattcgta tcctattttt cctcatttcc ttattatatt ttgttgttct
    12181 gttatctgcc aatccacata cagcttatta ttccgtatat ctttgataaa gggggaaata
    12241 gacaagacag cgacaacctt ctcccgatac aaaccacaac cggaatcagt gccgccattg
    12301 aaacgatcgt ccacctgctt gacatttaca tcagaaaacg gatataacaa caacgccttc
    12361 actaaagaag acatataggc attccaaaag gcattcctca tatccatctt ctccagtccg
    12421 ccctgacctc cgaaaccgac atcttcatac caacagtctt cttgtgaaga acaaatttca
    12481 actccgttca tatatgaaat tatttgagga gacgactgtg ttcccttaag ctgaaaccat
    12541 gactggtctg attgctccct acaactatcc gattccaaca ataaattgaa tttcacctct
    12601 tcttcctcaa ccctttcttt cgtaaacaaa agcatcaact cactaatgga atgataagaa
    12661 aaatcgcaac tatcattcga tggagtaaaa gatacctcca gaaatttctc tccaaatata
    12721 gaagtatatt catgctcaat ccggtaggaa acatgttgaa cgggatgttc gatcactccc
    12781 aatacaagca ttttgtctct ttggtcttcg tatgt
//
