LOCUS       c00081_gnlPro..        14739 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GHFDAKAO_81.
ACCESSION   c00081_gnlPro..
VERSION     c00081_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 13:57:18
            Original ID  :: gnl|Prokka|GHFDAKAO_81
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14739
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14739
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1268:4739]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1269..4739
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14739
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(222..923)
                     /locus_tag="ctg81_1"
                     /transl_table=11
                     /translation="MKNRIEYTPESSYCISSQLGKFLYRLDFGMILQDKVVEGISILGK
                     RMYQHGKLIVGVVISKNESKFFPFETKHFPANLLLGQIGLGTFQKELQLGSNGQRIEYQ
                     WRGNLFHNMVIPVLTEEFRLTEPVTNAFHIRHGKYFVLGTNSLKDELTCMQHSSRILLT
                     VDKHFSFQQENYNIFLTLSRRQMESSEVGSIYYCIVHSLGTLSALFFTSASRRVGHRQV
                     DLFVCCSDKNR"
     CDS             complement(1269..2024)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_2"
                     /sec_met_domain="Fer4_7 (E-value: 3.4e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(2058..3902)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201.2; E-value:
                     1e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.5e-62, bitscore:
                     201.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.9e-37,
                     bitscore: 119.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDIIVVGTGLAGASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQG
                     GINAAKNYQNDGDSVYRLFYDTVKGGDYRAREANVYRLAEVSNNIIDQCVAQGVPFARE
                     YGGTLDNRSFGGAQVSRTFYAKGQTGQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVL
                     IDGRARGIIAKNLVTGKLERFAAHAVVIATGGYGNAYFLSTNAMACNCSAAMACYRKGA
                     WFANPAYVQIHPTCIPVHGDKQSKLTLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKD
                     IPEEDRDYYLERRYPAFGNLVPRDVASRAAKERCDKGYGVNNTGLAVFLDFSEAINRLG
                     KDVVAQRYGNLFDMYEEITDVSPYENPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGE
                     CNFSDHGANRLGASALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQ
                     DKIDWMMNIKGKKSVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFI
                     PGDKEGMNVELDKAIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDEN
                     YFYVACWEYQGSDEKEPVLLKEPLVYEAIKVQTRNYKS"
     CDS             complement(4041..4739)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_4"
                     /sec_met_domain="SucD_FumR (E-value: 2.7e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(4902..5735)
                     /locus_tag="ctg81_5"
                     /transl_table=11
                     /translation="LVYRHYPKGQHFSAEKCTQNCMIFMLKGELLVNSDEYPGTTLQSR
                     QLILQAIGSKVELLALTEVEYIVYWFTELPLICEERYKEILKRSEAPLTYTPLTAISML
                     EGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCYYPLHQISTFFYPISTYTESFQYF
                     VMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPVYEWILDKKREGILNDLQYTKQR
                     ISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRLANGEKISIICKEQGKDQEDE"
     CDS             5910..6512
                     /locus_tag="ctg81_6"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             6509..6616
                     /locus_tag="ctg81_7"
                     /transl_table=11
                     /translation="MILGANYAEYAELDKLNPHNPRLSLFQVGYWIIVL"
     CDS             complement(6595..8217)
                     /locus_tag="ctg81_8"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(8240..8698)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_9"
                     /sec_met_domain="CTP_transf_like (E-value: 1.7e-18,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(8695..10629)
                     /locus_tag="ctg81_10"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(10747..11883)
                     /locus_tag="ctg81_11"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(12034..13014)
                     /locus_tag="ctg81_12"
                     /transl_table=11
                     /translation="MDILFLVGGLLLILLGANGLTDGAASVAKRFHIPSIVIGLTIVAF
                     GTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCTALFAPIAITRNTLKREIP
                     LCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIFLSYTFAIAKRDGSMKEPE
                     KEHLQEEDEIRLLPAWESALYILGGLAGLIIGGNFFVDGASGIARGLGVSESIIGLTLV
                     AGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLGCSASITPLRLTGITNFDL
                     WVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVLIYNL"
ORIGIN
        1 gaaatggaca atgccgatta ctaactgggg attgattatg aaccaattta tgcttatttt
       61 tgaaaacaga atccagatat aagagaactt ataactgaat cccgtttcta tttacacaaa
      121 attatggata ctgcctaaaa aactgaatta cttctatttt attcattccc cgcaacttct
      181 ttatgaaagt tttcggggaa tgtttctttt atgagtatta tttatctatt tttgtcactg
      241 caacaaacaa acaaatctac ttgccgatgc ccaactcttc tgcttgcaga ggtaaaaaac
      301 aatgcgctca atgtcccaag gctgtggaca atgcaataat atatgcttcc cacctcagag
      361 gattccatct gccggcgcga aagtgtgagg aaaatattat aattttcctg ctgaaaggag
      421 aagtgcttgt caacagtaag gagtatgcgg gaactgtgtt gcatgcaggt gagttcatcc
      481 ttcaagctat tggttccaag tacgaaatac ttgccatgac ggatgtggaa tgcgtttgtt
      541 accggttcag taagcctgaa ttcttctgtg aggaccggta taaccatatt atgaaagagg
      601 ttacccctcc attgatattc tatcctttga ccattactcc cgagttgcag ctctttctgg
      661 aaagttccaa ggcctatttg tccgaggaga agatttgccg ggaaatgctt tgtttcaaac
      721 ggaaagaact tgctttcatt cttggaaatt actactccga ctatgagctt tccatgctga
      781 tacatcctct tgcccagtat actaattcct tccactactt tgtcttgcag aatcatgcca
      841 aagtcaagac ggtagaggaa cttgcccagt tgggaggata tacagtagct actttccggc
      901 gtatattcaa ttctgttttt catcaaccgg tgtacgagtg gatgatggaa cggaggaagg
      961 aaagcgtggt ttatgaactt cgttatacgg atgcttctat atcagagatt tgctataaat
     1021 atggctttga atcgctgcct catttttcca atttctgcaa aaagaatttc ggggcttctc
     1081 cccgtagctt gcgtgccggc aatttatctg aagtaaacgg catgtcataa aaaaactcct
     1141 ccggcggttt cccggcagag gagtctcttg tgatattaat caaatatagt gaaagctgag
     1201 tgataaattt gagcttgctc aaaaggttta tccgaagcgc atcctatatt atttgcagaa
     1261 agaccggatt agtctttcag tttcgcaatg ataaagtcgc ggttcaggcg agcaatgttg
     1321 ctgatggaaa cattcttcgg gcattcagct tcgcacgcac gagtgtttgt acagttaccg
     1381 aaaccgagtt cgtccatctt gctcaacata gccttggcac ggcgcaatgc ttccggtttg
     1441 ccttggggca acaggttcag ctggctcacc ttggcagaaa cgaacagcat agcagaaccg
     1501 ttcttacaag cagccacaca agcaccacaa ccgatacagc tggcagcatc catagcctcg
     1561 tcagcgatgg gcttcggaat caggatagcg ttggcatcct ggggagcacc ggtacgtacg
     1621 ctgacgtagc cgcctgcctg cataatcttg tcgtaggctg tacggtcgac catcaagtcc
     1681 ttgataactg ggaaaccggc agagcgccac ggttcaacag tgatggtatc gccgtcgttg
     1741 aaacgacgca tataaatctg gcaagtcgta gcgccggttg caggaccgtg ggggtgtccg
     1801 ttgatgtaga gcgaacacat accgcagata ccttcgcggc agtcgtggtc gaatacaacc
     1861 ggttctttac cttcagaaat cagctgttcg ttcaggatat ccagcatttc gaggaatgaa
     1921 gtatcgcccg ggatatcttt catttggtat gtttcaaaag cgccttttgc tttcggaccc
     1981 ttctggcgcc ataccttgag cgtaaatgat atatttttat ccattttctt taattcttta
     2041 aatgttcaac ttcccgatta gctcttgtag ttacgagtct gtaccttgat tgcttcgtaa
     2101 accagcggct ctttcagcaa taccggttcc ttttcgtcag aaccctgata ttcccagcaa
     2161 gccacgtaga agtagttttc atcgtcacgc ttggcttcgc cttcttcagt ctgatattct
     2221 tcacggaagt gaccaccgca gctttcgtta cggttcagtg catcgtaagc aaccagctcg
     2281 cccatagtga tgaagtcgta cagacggata gccttgtcga gttctacatt cataccttcc
     2341 ttgtcgcccg ggatgaacag ttctttctcg aactccttgc ggacttcttt cagcttcttc
     2401 agaccttcct tcaagccttc agccgtacgt cccatgccta catattccca catgatgtgg
     2461 cccagttcct tgtggataga gtctacagac ttcttaccct taatattcat catccagtca
     2521 atcttgtcct gaacagcctt ttctgcagct gcaaattcgg gcaggtcggt agagaaacgg
     2581 ggaactgtaa tctggtcggc cagatagttc tggatagtgt aaggcaatac gaagtaacca
     2641 tcggccagac cttgcatcag ggcggaagca ccgaggcggt ttgcaccgtg gtcggagaag
     2701 ttacattcac cgatggcgaa cagtcccttg atggaggtca tcagttcgta gtcaacccag
     2761 ataccaccca tggtatagtg gatagccgga taaatcatca tcgggttttc gtatgggctg
     2821 acatcagtga tttcttcata catatcgaag aggttgccgt aacgttgtgc aacgacatct
     2881 ttacccagac ggttgatagc ttcggagaag tcaaggaata cggcaaggcc ggtgttgttc
     2941 acgccataac ccttgtcgca gcgttctttg gctgcgcggc tggcaacgtc acgcggaacg
     3001 aggttaccga atgctggata acggcgttcc aggtagtagt cgcggtcttc ctcgggaata
     3061 tcttttcctt gcagtgtacc ttcctgcagt ttcttggcat cttccagctt cttcggaacc
     3121 cagatacgac catcgttacg cagagattcg gacatcaaag tcagcttaga ttgcttgtca
     3181 ccgtgaaccg ggatacaagt ggggtgaatc tgtacgtaag cagggttggc aaaccaggca
     3241 cctttacggt agcaagccat tgctgcagag cagttacatg ccattgcatt ggtagaaagg
     3301 aagtaggcat tgccgtaacc accggtagcg attaccacag cgtgggcggc aaaacgttcc
     3361 aatttaccgg taacgaggtt ctttgcaatg ataccgcggg cacgtccgtc aatgaggaca
     3421 acgtcttcca tttcgtagcg ggtatacagt ttcacagtgc ctacgttcac ctggcggctc
     3481 aatgcagagt atgcacccag caacagctgt tgtccggtct gacccttggc atagaaagta
     3541 cgggatacct gagcaccacc gaaagaacgg ttgtccagtg taccgccgta ttcgcgggcg
     3601 aaaggaacac cttgtgcaac gcattggtcg ataatattgt tggatacttc agccagacgg
     3661 taaacgttag cttcgcgggc acggtagtcg ccacccttta ctgtatcgta gaacagacgg
     3721 tatacagagt caccgtcgtt ttggtaattc ttagcagcat tgataccacc ttgtgcagcg
     3781 atggagtgtg cacggcgcgg agagtcctgg atgcagaagt tgaatactct gaaacccatt
     3841 tcgcccagag aggcggcagc actggcaccg gcaagtccgg ttcctactac gatgatgtcc
     3901 aaacggcgtt tgttggcagg gtttactaat ttttggtgag ccttataatt ggtccatttc
     3961 tcagccaccg gtccttccgg tattttagaa tctatcttag tcataatgca atttacaatt
     4021 tagtcattta caatttgaat ttagcaagcg ccgcacaatg attttgcaaa gaatacgaca
     4081 actaccagag cgaagcagag gacaacgata gtagaataga tgttggagat acatttccaa
     4141 cggttaatcc atactttgtt gttccagccc aaagactgca tggagctcca gaaaccgtga
     4201 gtgaggtgga accacaatgc gcccagccaa acgaggtaaa gcactacgaa taccggattg
     4261 ctgaaggtgt tttgaatgtg atagacaccg ttggctgcat atgccagcgt gagggtgtcg
     4321 gcatgcatgc ccatgttgtg catcaactcg ggaagctgca ttttagccca gaagtttacc
     4381 aggtgcaggc ccaaacccac gattacgatg atacccagta cgagcatgtt ctgagaagcc
     4441 cattccacag tcttgggctt ttccgtaacg gcatagcgtt cgctaccacg tgccttacgg
     4501 ttctgcatag tcagccagaa agcgtagatg atgtggatga tgaataaggc agccagacct
     4561 accgtagcca ccaatgcgta ccagtttgct cccaggaact cacaaaccat gttgtagcca
     4621 ttagccgaga ctaatgcaac caggttcatc gccatgtgaa atgtcagaaa caggacaagg
     4681 gcgataccgg taacgctcat caccactttc cttcctacag atgaattact taaccacata
     4741 aatgattgaa tttaagttat ttaatagttt gaaaatttgt tctatcagga tacttctgta
     4801 aatgtttcgc aaaaatagga gaaatccagc gataaagcaa gcgattaaag aaataattcc
     4861 gtaatccggc agaatgcgaa gtttacggac aagtaaaagg tttactcgtc ctcctggtct
     4921 ttgccttgct ctttgcagat aatggaaatc ttttctccgt ttgccaaacg ttttctcagg
     4981 gcgcggggcg tgtctccgaa agagtctttg cagaagtggg caaagtggga tagggaatca
     5041 aagccatagc gggcgctgat gactgaaatg cgttgtttgg tgtattgcag gtcgttcaga
     5101 attccttcac gtttcttgtc cagaatccat tcatagaccg ggaccccata catattttta
     5161 aacagacggc ggaatgtggt ggtggtatat ccaccgaggt gggcaaactc ttccacattc
     5221 ttcaccttgt cgtagttctg catgacgaaa tattggaagc tttccgtata agtgctgatg
     5281 gggtagaaga atgtactgat ttggtgtagc ggatagtagc atgtcaatat gtataccaat
     5341 tcctggcatt tcatttcaat gtatttgctg cacgcatagg gttgctcgtt gaggtagcag
     5401 gcaaggcttt tcaggagccc ttcgagcatg gaaatcgcgg taagcggggt ataagtcaag
     5461 ggggcttccg agcgtttcag tatctccttg tagcgctctt cgcaaatcag aggaagctcg
     5521 gtgaaccaat agacaatata ttccacttcg gtcaaagcca ggagttctac tttggagccg
     5581 atggcttgca agatgagctg gcggctttgg agagtggtgc ccggatattc gtcactgttt
     5641 acaagtaatt cacctttcag cataaatatc atgcagttct gtgtgcactt ttcagcagag
     5701 aaatgttgtc ccttggggta gtggcggtaa accaatactc cttctgattt ttggggacat
     5761 accatacaat caatctgtcg gttgcagcaa gtttccagtc tcatgaaatg attagcgaat
     5821 tattataaat gtggcaacaa agatagaatt tttttgtgaa aactctatct atttgtccta
     5881 tctttgcgtc aaactaatat aaaggactta tgaaaaaggc tatttttttt gtatatttta
     5941 tctgccttgt tgtatccggt ctttcggcac agaattggga tattaacact ttgcatcggg
     6001 ttaacagttg ggatggcaag tttgtccgta actataataa gataatttca cgttcggagc
     6061 cctatgttgc tgtcggtgtt ccggtggcga tggcggttgc cgcttggata aaacatgata
     6121 agggtttgct gaaagatgcg gtctacgtag gtacaagtgt agcgggggct tttgttgtga
     6181 cttatggaat gaaatatctg gtggaccgtg agcgtcctta tgataaatat cccgacagag
     6241 tgcatgcata tagccatgaa ggcagcccgt cttttccttc cggacatacg gcgacggctt
     6301 ttgcccttgc cacctcgctc agtgtaaagt atcctaaatg gtatgtgata gctccgtctg
     6361 ccctgtgggc ttgttccgtg ggagtttccc gtatgaacga gggagtgcat tatccgtcag
     6421 atgtgttggc gggggctgca atcggtgctg gatgtgctgt ggtcaacatc tacgtcaaca
     6481 agtggctgaa taagtggctg ttcggagaat gattttaggc gcgaattacg cggaatacgc
     6541 ggagttagat aaactaaatc cgcataatcc gcgcctaagt ttgtttcaag tcggctattg
     6601 gataatagtg ctgtagatgc cttcgttcag cacttttaga gcttgctgca cgctctggtt
     6661 cgtgctgttc atcacctgga agtattcgtt catgtcccat aggtcacggg ctatcaaggc
     6721 tttaagttgt gtcttgatga gcggtaggga ttggttgtac tgtttctcgt caaacttgat
     6781 tttctctttg tcggcaagcg tacgtatttc ggcaaggaag ttatcgtcta tctcgaactt
     6841 ctcgttgaag gcttcgaatt tcttgtattt gttctgcaac tccttccggt gcttctcgat
     6901 gtagccggta gtggctttga taaccacgcc tttggctacg aggttgcggt gatagtctgt
     6961 gtactgggta gtgtcgatgg ggacgaagaa gtcgggcatg atacctccac ctccgtaaac
     7021 ggtacgtccc atacgcttgg tctgtgcttt cagggagtcg gcaaaatgga tactgtccgc
     7081 atgaatcatt tctccatgat tgaagcggtc tatcagttcc tggttatact tatcctgact
     7141 gttctcgccg gttaggcggc cgtcgaggtt ggcggtgctg tcgtaaggct tctggataca
     7201 acggcccgaa ggagtatagt agcgggcgat agtgaggcga atcatggaac cgtccggcag
     7261 gtcgatagga cgctgtacta atcccttgcc gaaggtgcgg cgtcctacta ccacgcctct
     7321 gtcccagtcc tggatggctc cggtcacgat ttcactggca gaagcggagt actcgtccac
     7381 caatatgatg agacggccgt tcttgaagtt gcccgtacct ttggcaaaga aatcactgcg
     7441 gcgtgcggcc cttccttcgg tgtagacgat gagttctttt tgcttcagaa attcgttggc
     7501 aaggtcgatg gcggcattca gataccctcc tccatttcct tgcaggtcga ggatgaggtc
     7561 tttcattcct ttcttttgca ggcttttcag ggcttctgca aactcttcgg cggtggttgc
     7621 cccgaagcgg ttgatacgga tatagccggt tttgggttgt atcatgtaag atgcgtccag
     7681 gctgaggatg ggaattttgt cacgcttcac ggtgaagtac agctggtcgt ccacgccacg
     7741 gcgcacgatg gtgagtttca cttccgagtc tttcggtccg cgcaggcggc tcataatatc
     7801 ttccgtgctc atttttactc cggcaatggc gctgtcattg acggctacga tacggtcgcc
     7861 ggcaaggatg cccaccttct cggaaggtcc gttgctcacg ggttgtatca caagcagggt
     7921 atcttctatc atctgaaact gtacgccgat gccctcgaaa ttgccttgca acggctcgtt
     7981 catcttcttc acttcttcgg cgttgttgta ggtggagtgc gggtcgagtt gtgccagcat
     8041 cttgatgatg gcttcttcca ccagcttgtc ttcatccacc ttgtccacat aaaggttggt
     8101 gatggcaaac tctgccattt gcagtttgcg cagggcttca ttgttcggct tttgcgcttg
     8161 tgccgtcacc gcgcatatac atattataat agtaaatagt tttttcatca tttccatttt
     8221 aatccctaat cctttatcct taatccctaa tctccattcc ctccggtatg aacatgctta
     8281 tgtccttgcc gtattgcagc agttcgcgca cggtggtgga actgacgcag gtaagttccg
     8341 gctcggtgaa gagcaggatg gtttctatgc cggtcagttt gcggttgatg tcggcaatgg
     8401 tttcctcgta ttcgaaatcc ttcacggtgc gtatgccgcg tattatcaga ctggcatcta
     8461 cctgccgggc aaagtcgata gtcaggcagt cataggactg cacaatgatg cgcggctcgt
     8521 tccggtagta gtctcgtatc atttgttcgc gcttttccaa ggggaaatac gtattcttat
     8581 tttcattgat gccgatgcct atgacgattt cgtctataaa agtcagtgca cggctcacta
     8641 ccgaagagtg tccgatagta aacgggtcga atgttcccgg aaagatagct cttctcatga
     8701 tgccaaatct tcttctataa ccaagttgtt gataataaag ttttgtcgtt ccatggtatt
     8761 cttacccatg tagaattcca gcagctcttt tacgaggtct gtcttgcgca gggacacttg
     8821 ttccagacgc atatccttgc cgataaaatg cttgaactcg tcgggcgaga tttctcccag
     8881 acctttgaat cgggtgattt cggggttggg acccagttct tcaatggctt tcacacgttc
     8941 ctcctctgta tagcaataac ttgtcttctt tttgttgcgc acgcggaaga gaggggtttg
     9001 caggatatat acatgccctt tctttatcag gtcggggaag aactgcagga agaaggtgat
     9061 gatgagcagg cggatgtgca tgccgtccac atcggcatcg gtagctacga tgactttgtt
     9121 gtagcgcagt gtctctatgc cgtcttctat attcaaggct gcttgaagca agttgaattc
     9181 ttcgttttca taaactactt tcttggtgag tccgtaggaa tttagcggtt taccacgcag
     9241 gctgaatact gcttgggtat tcacgtcgcg gctcttggtg atggaaccgc tggcggagtc
     9301 tccctcggta atgaagatgc aggattcggt ttcctggtct ttgcctttac cgtcactcaa
     9361 gtggtagcgg cagtcgcgca gcttgcggtt gtgcaggttg gctttcttgg cgcgttcgcg
     9421 tgccagcttg gtgacgccgg caatggcttt gcgctctttc tcggagtctt gtatcttttg
     9481 cagcatcact tcggccacaa gcgggttctt gtggaggtag ttgtccactt ccgtcttgat
     9541 gaagtctcct acgtatttgt tcaccgtggg gccggcgggc ttgtgttcct gcggcgcggc
     9601 aggccacatg ttgttgctgc ccagtttcgt tttggtctgg ctctcgaaca tgggttcctc
     9661 cacgtcgatg gcaatggcgg ctaccagtcc gttgcggatg tcggcatatt cctggttctt
     9721 gttgtagaac tccttgatgg tacgggcaat gtgttccttc aaggcagtct ggtgtgtgcc
     9781 gccttgggtg gtgtgttgcc cgttgacaaa ggagtagtac tcttcgccgt attggttggt
     9841 gtgtgtgaag gcaatctcga tgtcctctcc tttcaggtgg atgatgtcgt aaaggccttc
     9901 gctggtcatg ttgtctttca gcaagtcctc cagcccgtgg cgggaaacga tgcgctggcc
     9961 gttgtaaatg aaggtgaggc ccgtattcag gtaggtgtag ttgcgcagca gggtttctac
    10021 gaactggttc tggaaggaat agttcaagaa gagtgtggcg tccggttcga agaagatata
    10081 ggttccgctt tcttctgtcg agtcttcggt cacatcactc aacagcgttc ctttttcaaa
    10141 gatggcgata cgtaccttgc cgtcgcggta gctgcgtact tcgaagcggc tgctcagcgc
    10201 attgactgcc ttgataccta cgccgttcag tccgacactt ttcttgaaag ccttcgagtc
    10261 atatttaccc ccggtattca gtttgctgac cgcctctacc agtttgcctt gcggaatgcc
    10321 tcgtccatag tcgcgtacgc tgacacgcag actgtcttct atagtcactt ctatacgctt
    10381 tccggcaccc atcttgaact cgtcgatgct gttgtccatc acttctttca gcaacacata
    10441 gatgccgtca tcgttctgtg agccgtcgcc cagacggcct atgtacatac cggaacggac
    10501 acggatatgc tccatgtcgt ccaggtggcg gatgttgtcg tcggtatatt ccacgctgga
    10561 aacggggctc tctgtgatat tgttgtctgc ttcttccagc ggcagggtca tattgttgtt
    10621 atcttccata agtacgttat tccttcatat tgcgcattgc gacaaaggta atgagaaatt
    10681 cgggggttcg caaaaaaata atgtctttta tggacttctg acaagcttat attctggatt
    10741 tagaacttat tttattcctt tcacaaagca tcttctccgt ttatgctgtt ccgtcttgaa
    10801 gtactcccac tgcgcttgca ccttgccgtt cagctccagc tccggattac tctcggcata
    10861 ctcaaaacca agttgctgat agacggggat aaggtcggag aacaacaatg catttacccc
    10921 cttgttctga tactccggtt tcacggcaac cagcagcaaa tcgagcatct tgggatattt
    10981 cttcaagaag atggtcttgg ccaggtgata ccaacccata ggaagcaggc gcccgtgggc
    11041 tttttgcaac gcttcggcga gtgacggcat ggaaatgcct acggcaagca gctggtcatc
    11101 ggcatcggta atcaatgtca ccatgcgtag gtcgaggatg ggcaggtaca tcttgacgta
    11161 ttggtcaatc tgccgttggc tcagtgcaga atagccatag agtggctgat aggcttcgtt
    11221 catcagttcg aagatggcct gaccgtagtc ttgggcaatc ttcttggcag atgtgtattt
    11281 ctttaccttg aggttatact tgcgctggat gaggtcggag atgcgcttgt gcttgtcggg
    11341 tatggcgtcg ggaatgtaga ttttgtactc cacccaatcg gcatccttct caaagcccat
    11401 gcgttccaga tgttgcggat agtagggata gttataaatg gtggccatgg tgctgagctg
    11461 gtcgaatcct tcgatgagca taccttcggc atcgaaatct gtgaatccca gcgggccttg
    11521 tatatgtgtc attccccgtt cttttcccca ttcttccacg gtgcgaatca gggcatcgga
    11581 gacttccgca tcatcgatga agtctatcca gccgaagcgg acttcctttt tgttccaggt
    11641 ttggtttgcc ttgtggttga tgatggcagc tacacgtcct acgattttac cttcccgata
    11701 agccaggaaa tagtcggctt cacaaaattc gaatgcagcg tttttcttct tgttgaaggt
    11761 gttgagcatg tcatcgaaaa ggtcggggac ggaataaggg ttgtttttgt atagcaggta
    11821 gttgaaacgg ataaagcgct ccagttcccg tcttgtggtt actttcttga ttgtaattgc
    11881 catagttgtt caatattgag accacaaagg taatgcaaac tgagagcaga acaaaataag
    11941 cttgcttatt ttttatgccg aggtacagct tgccttattt aaaaatacgt gataatcttt
    12001 aaaataccgc gtagggtgtt tgtaaatttg ctgttagagg ttgtatatca gtaccgctgt
    12061 gtaggcaatg tagcagagaa tcagaatgct tccttccacc cgggtgatga tgcgtttccc
    12121 gaaaaagata ccgaacagcc aaagcaggat gctggaccct acgagtaccc acaaatcgaa
    12181 attggtgatg cccgtcagac gcagtggagt gatggaggcc gaacaaccca gtacgaagaa
    12241 tatattgaag agattacttc cgatgacgtt tccgatggct atttcggggt ttttcttcaa
    12301 ggcggctacg atggaggtgg cgagttcggg taatgaagtg ccgcctgcta cgagcgtgag
    12361 accgatgatg gattcgctga cacccaatcc gcgggctatg ccgctggcac cgtctacaaa
    12421 gaaattacct ccgatgatga ggccggcaag tccgccgaga atgtataggg cggattccca
    12481 cgcgggtaac agcctgattt cgtcttcttc ctgtaagtgc tccttttccg gttccttcat
    12541 acttccatcc ctttttgcaa tggcaaaagt ataactcaga aaaatggtaa agaagcatag
    12601 cagcaatagg ccgtcggtga tgctgagtat gttctcccca ctgctgtcca gtaagacgtc
    12661 gttggcacaa atcagcaggg cgaaggatga aaggatgcaa aggggtattt cgcgtttcag
    12721 tgtgttacgg gtaatggcta tcggggcaaa aagggccgta caacccacaa tcatcagggt
    12781 attgaacgta ttgcttccca ccacattgcc gatggcaatg tctgcactgc cttttagggc
    12841 agaggatatg ctgacggtga gttccggtgc ggaagtaccg aaggcgacaa tggtaagccc
    12901 gatgacgatg gacggtatat ggaaacgttt ggcaacggat gcggcaccgt ctgtcaagcc
    12961 attggcaccc agaagaatga ggagcagtcc tccgacaaga aacaatatat ccataggtat
    13021 gtcaattttg agtacaaaga taatgcaaac cggatacaga actttcatgt ttgcatgaaa
    13081 aagttatgtt gattaggata ggaagttaaa aacattccgt atgtttgaag catttattgg
    13141 gtatatttgc ataattaaag aatcaaatca agaagtttat atatgaaggt tatccgtgct
    13201 ttctgtcttt gttggctgtt gatgctggca gacggagtgt cagctcagtt ggtagataaa
    13261 gtgctcagtg ttttaggtga ggatagtgtg gggagtgtca cagtggcaag gactgactcc
    13321 gattcgattc agttgtcgct tgtccggcag gagttggaaa cagcccggct gaatgaggcg
    13381 aacctgcgga tggaaatgga gcagatgaag ttggcgggct atgcggccga ttcggtgaag
    13441 ctggcattgc agaaacaacg cattgattcg ttgcggacgg tgacaccggg tattccggtg
    13501 gtggtggaga aggacacttt gttctatctg tatgccaagc gtggagggca tacgccccaa
    13561 cagcgagcca aagatgtaag caacgtcatc gaagcattgg gcacgcgttt caatctgcgt
    13621 ccggactctg tttatttaga gagtacggat attgttacag acttgatgta tggcgaaaag
    13681 gtcatcattt cctttaccga tcaggatgct ttgtgggaaa actgtacccg cgaccagctg
    13741 gccgccagca agaggcatgt cgtggtggac aaactgaaag ccatgcagaa ggagcatagc
    13801 ttgtggcagt tgggtaagcg tatcttgtac tttatcctgg tgcttgtggg acagttcttc
    13861 ttgttcaagt ttaccaactg gctgttcaga aaactcaaac tacgcattca gaagctgaag
    13921 gataccaagc tgaaaccgat ctctattcag gattatgaat tgctggatac gcagaagcag
    13981 gtcaacctgc tggtgtttgt tgccaacctg gtgcgttatg tagtcatgct gttgcagttg
    14041 ctgctgacgg ttccgttatt attctccatt ttccctcaga ccaagagctt ggcttataca
    14101 ttattctcct acatctggaa tcctataaag gtcatcttga atggaatagc cgactatata
    14161 cccaatctgt tcactatctt tgtgatatgc tatgcggtga agtatctggt cagactggtg
    14221 cgttatcttg ccaatgaggt gcaggctgaa cggctgaaga taaacggctt ctatccggat
    14281 tgggccattc ctacctatca tattgtgcgc ttcttgcttt atgcgtttat gattgccatg
    14341 atttaccctt atctgccggg ttccaagtcg ggagtcttcc agggaatctc cgtgtttgtc
    14401 ggcttgattg tttcgctcgg ttccagtacg gttatcggca atatcattgc aggactggtc
    14461 ataacctaca tgcggccttt caagctgggt gaccgcatca agctgaacga tactacgggc
    14521 aacatcattg agaaaacacc gctcgtcacc cgcatccgta ctccgaagaa tgaggtggtg
    14581 accattccga actctttcat catgtcttcc catacggtca attacagcca gtctgcccgt
    14641 gagtatggat tgattatcca ttcggaggtc agtattggct acgatgttcc gtggcggaag
    14701 acacatcagc tgttgataga ggctgcattg aatactcct
//
