LOCUS       c00022_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POPEFCFF_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:16:52
            Original ID  :: gnl|Prokka|POPEFCFF_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43786
            Orig. end    :: 68424
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[53786:58424]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(1023..3755)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_25"
                     /sec_met_domain="Peripla_BP_1 (E-value: 4.4e-07, bitscore:
                     22.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRICFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVVHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIRLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCTFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMSEEVSMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
     CDS             3852..4319
                     /locus_tag="ctg22_26"
                     /transl_table=11
                     /translation="MKIINEALLDETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSVIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             complement(4558..6387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_27"
                     /sec_met_domain="Peptidase_U32 (E-value: 9.4e-74, bitscore:
                     240.5, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARAAAG
                     NSLEDIRELCEYAHLYGARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVSNKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDAGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTTFLLEGRTADITAFNTPKSLGEPVGMVKEIKGNSFTVAGLKQL
                     NNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLTPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSVEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARREQQDNIRTQLSKLGNTP
                     FEASKVVVGLSENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(6410..7342)
                     /locus_tag="ctg22_28"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGDL"
     CDS             7451..9856
                     /locus_tag="ctg22_29"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDVDGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             10001..10408
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_30"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.5e-26, bitscore:
                     85.9, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             10521..12074
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_31"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12090..12983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_32"
                     /sec_met_domain="OAD_gamma (E-value: 1.1e-11, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGKTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             13006..13437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_33"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.1e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             13442..14638
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_34"
                     /sec_met_domain="OAD_beta (E-value: 1.6e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(15259..17307)
                     /locus_tag="ctg22_35"
                     /transl_table=11
                     /translation="MHSRDMEYIVGLLKNGKDAEAILSVRRKLNMAFLARTTDLSGKLP
                     VLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAAALPQTLLAFVGLSG
                     RSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSIISLKEPFLSRGCRM
                     SVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAPGADRNGQIATLFSV
                     ILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRYEALKKYKIDVRMAF
                     RTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMSGGVEYLDRSMIQFV
                     YKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDHFLGNLPAWDGKERI
                     RALAGRVPCDNPIWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLVGGQGCGKSTFCLNL
                     LPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVKSSHQSFLKHILQKAVVNTR
                     LPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRIDYAQPIDYDQLYAEA
                     KELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAEDIEEAKPLLASEIL
                     DMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEVDG"
     CDS             complement(17349..17735)
                     /locus_tag="ctg22_36"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             complement(18338..19057)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_37"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.8e-23, bitscore:
                     76.6, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCILNIETSTSVCSVALSMDGEVLFAKASFDGPSHAALLGVFVE
                     EALSVLKKKGKKALDAVAVSSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAAT
                     VNSKGDSQIVSITDDCLYCAMLDARRMEVYAAIYDASLKPVRETKADIVEVGTYASYLE
                     KGKVCFFGNGASKCKSVITSPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFY
                     LKEFQATVAKNKVLLAR"
     CDS             19281..20153
                     /locus_tag="ctg22_38"
                     /transl_table=11
                     /translation="MIQSMTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEK
                     EMQIRSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPA
                     DWFQTLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIA
                     NISRLLSEVEPYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKN
                     RLDNHLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQ
                     IKEQVLNVL"
     CDS             20163..20732
                     /locus_tag="ctg22_39"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAQKEALKVIKEFLKKA"
     CDS             20729..20902
                     /locus_tag="ctg22_40"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             20887..21498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_41"
                     /sec_met_domain="CTP_transf_like (E-value: 2.2e-24,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTVSKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             21589..23319
                     /locus_tag="ctg22_42"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             23330..24325
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_43"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 8.1e-33,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
ORIGIN
        1 cgtacagaca taagcagctg tgcggacggc aaattcatgc gcttccctta gcgaagcccc
       61 tttcaacaac gaaatgacca gtgctccgga gaaagcatca cctgctccaa ccgtatccgc
      121 cacctgcact tccggggttt gcaaagtcga ttcttcatta gcggtatata tcgtactata
      181 agctcctccg gccgtcagaa ccaccaagcg gagattatag tgttctataa accaatgagc
      241 cacctccttg tccgttcctt ccaaatgaaa catatcccgc aggacgacca actccccatc
      301 attcaccttc aacatatttg ctagataaag cgactcttcg atcaactctt tcgtataata
      361 atgctgacgc aaattgatgt caaaacaacg ataagcatcg tccggagcaa aagaaagaat
      421 cgcttgtatc gtctctctcg actgtgcgga acgctgtcct aacgtaccga agcaaatggc
      481 acccgcccgt tcggccaaat caatcgcatt tgacgtcgga gaaagatgat cccaagctac
      541 acgttcatta ataatatagt cagggacacc atcctgcaga gtaacctgta ccgttccggt
      601 cggataaggg actttctcga tcagataccg gatcgaatta ttatccagtt cttcgaggat
      661 ttcgcgcccc agcccatcgt ctcccacggc gctgatagca tatccttccg cccccaaccg
      721 cgacgcatgg tagacaaaat tgataggagc accacctgct ttctttcctg ttggcaacat
      781 gtcccacagg agttctccta tgcctactac gaccggtttc ttattgttgc tttgcattgt
      841 ttcattatag tttatttgac aaggataatt tattatctac gatgcaaaga tagagacagg
      901 tagcagatgc gacgataact aatgctacaa gattgataac acttgttaca ttatactctt
      961 attttcgagt tacatgcaca agtgttacac aaatgtaacg agcgttatca aagagaagaa
     1021 tattattcct tttccagata ctccgtcgga gtaatattgt aaacggcttt aaaacatttc
     1081 gagaaataag caggcgaacc gaagcccgtc gcataagcca cctcattcac attcccggct
     1141 ttccgtcgga gtagagcagc agctttcttc aaacgatagt tacgcaggaa atcggtcggt
     1201 gtcactccgg caagctcctt caccttccgg taaagatgca cacgcgacaa gcccaatttt
     1261 tcactacctt tctcaatact gaaatccgga tcggcatagg actcttcgat cagtttcaag
     1321 aaacgattca taaaaagatc gtccatgctt cccgcttttt cctccttcac ggaaacagca
     1381 ggcgaagaag catcgcgagc ataagcctca cgcaaccgga cacggtcctc cagcagcttg
     1441 atgatacgca gtttcacgac ttctatgtta aaaggtttct ggatatacgc gtccgcacca
     1501 ctggcagccc cgtacatctg ttgcttgtcg tcggacaaag cagtcaacag cataaccgga
     1561 agatgactca ggacaatatc cgacttgatc ttacgacaaa gatcgaaacc gttcatttcc
     1621 ggcatcatca catcgctgat aaccatcgaa acctcttcgc tcatcagcac ctccaaagcc
     1681 ttcacgccgt tatcggcaac caacacacgg aagttctgtt ttaattccgc ctgcaagtaa
     1741 ctctgtatat caagatcatc ttctacgacc agaacagtat aattgtaggt acggttcaaa
     1801 acctcctgca attcatccgt gttcaagtcg gcgacaccac tggaaagctc ggttacggaa
     1861 agatcgaatg tacaagattc gtcaaaatga gatttacctt tcaagaggat gaccgtaaag
     1921 acagtactct tatgcggaac actctccacc cggatcgtgc ctttgtgcat gtggacgaac
     1981 tcacgcgtca agtgcaggcc gatccccgtc cccgtcacat agttctggtc accggtaaag
     2041 aaacggtcaa agacggaagc aatattttcc gacggaatgc ctttgccatt atcttcgaca
     2101 gaaagctcga cctgatctcc tttatctttc agacggatcg tgaccgtacc tccgtccagc
     2161 gtgaacttga atgcattgga caaaagattg gccagaatct tctccatctt atccctgtct
     2221 acccatatat taacagaagg gcagtcatgc tcaaacgtga aatgtatctg cttggtggca
     2281 gccatcgtat cgaaataaga tttcacttct gccacaaaag caactaaatc tacctctccg
     2341 acccgcatat tcatcttatt gctctctacc tttcgaaaat caagtaactg gtccacgact
     2401 ctcttcaacc tttccgcatt tttccgaatg atacggatat cgtctgccaa tgaagaacct
     2461 tccggagcct ctttcgacag cttgccgagc ggaccaagga tcaacgtcaa cggcgtcttg
     2521 atctcgtgtg tgatattggt aaagaattgc agtttctgag ccgtcgactt ctcaatataa
     2581 cggtttgcct cagccaattc ttctttttgc tgttgtacct gcaagttcgt acgtttcagc
     2641 tcgcggttct tccgcttcac cgcccggttc acatggacca cgtacaaggc ggacaaaagc
     2701 aacatcccca tcagcaaaag gataatgccg acggagtttt ggaggaacgt gtatttggaa
     2761 agcatactct ccaaattctc ccgttgcaac tcgatctggt gctgatagtc gaccacctgt
     2821 tcggactgga taaacagcgt tccggcattg ttcttatcga tcaaggcaga agagagcaaa
     2881 tattgccggg acacatcttc tccgttcaat atctgcatgg ctacacggat agcaaggctc
     2941 ccacccgtcg gatacaagac cgaagcggcc aactctccgt gcatgacggc ttccagcccc
     3001 gatccccgtc ccgaaacggc atcgatcccc acaaaacaaa tcctgtccgc caatccggga
     3061 tgcatccttt cgattgccct gcgggcagcc attgccatca catcattatg tgcaaacaca
     3121 acatccacct cctccagcga atccatttcc gctatctcct tctccaccgt ttccggcttc
     3181 catttcccaa atatttcctt caccttgatg cgggagttca aaacctccat aaaaccgcga
     3241 tggcgatcct gcgccggaga agaaccggac aagccccata cttccaatac ggtaggatat
     3301 ttctctttca cctgtcggtt cacgaaaaag ccggcctggc gaccgatctc gtaattgtta
     3361 ccaccgatat aagtcgtata ttcgtccgaa ctgatcttcc ggtctaccag gatagtcgga
     3421 atgccggcac ggtaggcctc aatcgcaata ggagtgacag gttccgattc attggcggag
     3481 ataatcaata gatcgacctt acgttttatc aggctgcgta tctgctccac ctgcaacaaa
     3541 ctactgtccg ctgcatcctc gactaacagg gagacgcccg gatattcgga ggcctgcacc
     3601 ttcatatcca gcaacatcga tttacgccaa gaaccttcaa gcgtacactg cgagacgccg
     3661 ataacaaact ttttcttctc cgaatctgtt ttgcaggaaa agcaggatgc cagaagtaag
     3721 accagcagag cgtaataagt tagagcaggt ttcattctgt tttatttaca ggtttctgca
     3781 aatgtacgga gaaatggcat accagccaat atttattttg tacattcgtc ctccagtaat
     3841 caattattcg catgaagatc ataaacgaag ctttattgga tgaaacgacc gggcgtgcca
     3901 aacagtcgcc tcggctacgc atgaactaca attttcatga gcatttggac gatcccgtca
     3961 accgtttgct caatgccctg gaaccgggaa cctacctccg cccacaccgc catctgaacc
     4021 ctaaaaaaga tgaaatattc ctcctgctgc gcggtcgcat tgctgtattc ctctttgaca
     4081 acaaaggaga aatcacccaa acacagatac tcgatccgaa agaaggtgtt tacggcgccg
     4141 aaataaaggc gggaacatgg cacgggctgt tagttctaga atccggctct gtcatatatg
     4201 aaatcaagga agggccgttc gctccgctcg ctccggaaaa tttcgctccc tggagtccgg
     4261 ctccagaaga cacgaaaggg gtggcaaaat atatggagtt attaggaaag gcaatataac
     4321 cttgcactac cttcccgttc cccttaaaga aaactttagt ttctcttaag ggaaacttta
     4381 ttttcatagg gatgaaactt ctttttcatc cccatgaaac tgtcgttcca tccttatgaa
     4441 actgttatca catacctatc ggctccttta ttgctggaat acttttgtca aacggatcat
     4501 ggctttttca ccggacagtc attcttatcc gtcctgacaa tagcgttctc ataattttta
     4561 actttcaaat accaacatct gacaatgctt gcagtcgaac tgcaaccgga ggcgcgtatc
     4621 tttataaagc agataatacg gttccttgta gggagacttg tctttctgat aagtaggaca
     4681 ccaccccatg ctgtagcgca ggcagtgttt ggtaaacatc aacggaacat ctttccgggg
     4741 agacagttca aatgccgggt caatctgttc caccccgtga tcctggtaga acgaacgggc
     4801 tttcccgttg gcaacattcc ccaaataagt aagttggcgt tcggggaaag gtatcgacac
     4861 ggacggctgc acacgtttca ctgtctcacg aggatagcgg gcacggcgtg cttccagcaa
     4921 cttctccact cctctacggc gcatatcggc aagcagagaa gagggaacga accagttttc
     4981 agacaaaccg accaccacct tcgatgcctc gaaaggcgta ttccccaact tggatagctg
     5041 tgtccgtata ttatcctgct gttcacgacg cgccagctct ttcgcaaacg gctcggtcag
     5101 catgatccgt gctcccgtct catcctccat acaaagcgta aaaccgaagg gattgtccaa
     5161 gaactcgatc tccacggaca gcttgcgttc ggctgaaggc ttggcgagca gtttatcaaa
     5221 tgcctggtcg aaattgcggt aaagcggagt cttgggggta agctgcggca tatccagcgg
     5281 aaacacccgg tttgcctcca cccggttgac gcggaaaccc tccaactcgc ctttcctatt
     5341 aaagaaaaca agcccgtctc cattgttcaa ttgcttcaag ccggccacag taaaagaatt
     5401 gcctttgatc tctttgacca tcccgacagg ttcgcccaac gacttaggtg tattgaaagc
     5461 ggtaatatcc gccgtccgcc cctccaaaag gaacgtagtg aacccacggt taaaactctt
     5521 ttcagctacc ggctcgaacg tataagtgct tcgaccagca gaagcacgac gatattccgg
     5581 acggcgggac aggactgcat ctaacttctt ccgataataa gccgtgatat tcttgacata
     5641 gccggcatct ttcaaccgcc cttcgatctt gagggaagaa acacctgcat ccaacagggc
     5701 ttccagctga tccgaacggt tcatgtcctt gagcgaaagc agatgtttgt tgctgacgat
     5761 ctccgtccct gtcgcatcga ccatcgtata gggcaggcgg caatattggg cgcattctcc
     5821 gcgattggca ctacgtccac tcaaagcggc gctcagataa cattgcccgc tatagctgac
     5881 gcagagggcg ccgtgcacga atacttccag cggaacggta gtcgcttccg atatccggcg
     5941 aatctcgttc agcgacaatt cacgtgccag aaccacctgt gtaaagcctg cggcttcgag
     6001 gaaacggacc ttttccggtg tacgattgtc cgtctgcgtg ctggcgtgaa gcggaatagg
     6061 aggcaggttc agccgggtaa tccccatatc ctgaatgatc agggcatccg tcccgacacg
     6121 ccagagatcc cagatcatcc gttcggcttc ttccaactca tcttctttca atatcgtgtt
     6181 aagcgtaaca tagatgcggg cgccatacag atgcgcatac tcgcaaagct cgcgtatatc
     6241 ttccaaagag ttgccggcag cagcacgcgc accgaacttg ggtgcaccga tatagacggc
     6301 atcggcaccg tgattaatcg cttcaatccc gcaattgagg tctttagccg gagagagaag
     6361 ttctatagga cgggattttg tttgcatgct attatttctt atttcttgat tacaaatcac
     6421 ccaacttgct gatatcctcg atacggaacg gggtttcctg atagacataa tagttcagcc
     6481 agttggtgaa cagaagattg gcatgaccac gccagcggac caccggaccg agggccggat
     6541 tgttattacg gtaatagtta cggggaacgg caattggcaa tcccttgttc acgtcgcgca
     6601 tatactcgtc attcagcgtg taaggcgagt attcggaatg cccggtgata aaaaactcgc
     6661 gtcctccgcg cgccatcgcc atatagacac cagactcttc gctttcggac aagagcgtca
     6721 aatcgggaac tttcatcaca tcctcgcggc gtatctccgt atgccggctg tgcggcacat
     6781 agaactcgtc gtcgaagcct cggaagatcg gcacataggg ctcgcgcaac gtatggcgga
     6841 acacgccgaa catcttggct ggcagatcat atttggggac accataaaaa tggtacaacc
     6901 cggcttgcgc cgcccagcat atatataagg tagaagtcac atgcgtacgc gcccaatcga
     6961 atatctcggt cacttcctcc caatagttca cttcctcgaa aggcatctgc tctaccggag
     7021 cacctgtgat aatcatgccg tcgtaaaaat catcctgcat ctcgtcaaag tctttataga
     7081 attccttcat atgctcgatc ggcgtgttct tgggagtatg gccttttatc ttcataaagt
     7141 cgagctccac ttgcaagggg gtattgctca ggaggcgaac aaggtccgtc tccgtcgtga
     7201 tcttcagtgg catcaagttc agcacaacta cacgtagcgg acgaatgtcc tgctcagacg
     7261 cacgcaacga gtccatcaca aagatgtgct ctttcttcaa cagctcaaca gctggcaagt
     7321 tcttctgtag gtttaaaggc atcttctttc cttaattatt tatataaggc acaaagatag
     7381 tgagaaattg cctttcattg aaaataaatc gttgtttccc gcgtttgtag atttaataat
     7441 tagatggaat atgaagattc gtgcaatagc tacactacta tttatattat tttcgataag
     7501 tgctttcggg cagggacgtg ccaaaatcag cggttatatc cgcgacgtgg acggtaatcc
     7561 gctggacttg gtcaatatcc gggtcaagaa cacgttaaac gggacgatga gtaatgaaaa
     7621 aggccactac tcgctttcgg tcgctaccgg tgactcggtg acgcttatct attcatgcct
     7681 gggctacaac aaggccgaaa ggatcctacc tcaggtaacc aaagatatgc gtctcaacgt
     7741 gcagatgaac tatacatcac tcgaactggg agaagtcgta gctaccgcca tccgaaagca
     7801 gacaaccacc cttgaaaccc tgaatgccga ccgcgtcaaa ctactccccg accctgccgg
     7861 aggaagcatt gaaagtctgg tcgttacatt tgctggcgtt acttccaata acgaattaag
     7921 ttcgcaatac tccgtacgcg gcggcagcta tgacgaaaac atcgtatatg tgaacggact
     7981 ggaagtgttc cgtccgctgc tcatccgttc cggacaacag gaagggttga gttttatcaa
     8041 cccggacatg acggaagccg tcaatttctc cgccggagga ttcgaagccc gttatgggga
     8101 caagatgagt tccgtgctgg acatcaccta caaaaaaccg aaaggattcg aaggttcggc
     8161 ttccgccagc ctgctgggag ccaatgctta tgtgggcagt tcttccggca agttcacaca
     8221 ggtgaccggt ttccgttaca aaacaggacg atctcttttg aaaacaaccg atacggatgc
     8281 cgaatatgat cctaatttca ttgatttgca gacttatatg acataccagc ttgcccccaa
     8341 atgggagatc aactttctcg gaaacttagc cataaacaat tataagttca ttccccacac
     8401 ccgagagact tcttttggaa cggcaacaaa tgccaaaaaa tttaaagtat tcatgagtgg
     8461 ccaggaacgg gataagttcg aaacgttatt cggagcactc actttaaagc ataacctgaa
     8521 cgacaatacg gaactcggct tgcaagcatc cgcctttacc agtaaggaag aggaaggata
     8581 tgatattgcc ggtgattact ggctgggaga tgcagccgaa gaaggaggcg gagaaataca
     8641 gaaattatcc atcgcacgct ataacgagca cgctcgcaac cgtctgcact ccaatatcat
     8701 gaatgtcggg cattatggtg tcgctcgcat aaaaaacaat acgttgaaat ggggtgctac
     8761 cgtccagttg gagaaaatca acgacaagat cagcgaatgg gaaaaacgcg actccgccgg
     8821 atactcgtta ccgcaagggg gcgggaatgt caacgtgatc gcaaacctgt tctcggataa
     8881 caaactggaa agcacacgta tttccggcta tttgcaggat gtattcaagt ttcgtaccaa
     8941 acaaggactg ttcacgctgg ttggtggtgt acgcggcagc tattggagtt ataacaggga
     9001 atttatattc agcccgcgtg cttcaatagg tttcattccg aacttcgacc agaacctgac
     9061 atttcggctg gcttccggtc tgtattatca gtctccgttc tataaggaat tacgtacaac
     9121 tgtgcaggac gaacacggca acagtatcat acaactgaac aaaaacctga aatcacagcg
     9181 ttccatccat gtcattgcag gaggcgatta tacattccgg gcatccggca gaaatttcaa
     9241 agtcagtgcc gatatgtatt ataaaaaatt ggataacctg aacccctata cggtggataa
     9301 tgtcaaaatc cgatactacg gcgagaactg tgcgcaaggc catgcgatgg ggctcgatgt
     9361 caaattcttc ggcgaatttg ttccgggtac ggactcctgg atcagcttct ccctaatgaa
     9421 agcggagcaa agcatccgag ggagcgaata tgtaccgatg cctaacagcc aaggttataa
     9481 tgtctcgctc ttttttcagg attatttccc cggatacaaa cgtgtcaaac tgaatctgaa
     9541 aggcgtactg tccggcggcc ttcccgtcac agccccacgt acaggctacg aggacggcta
     9601 tttccgtact ccgacctaca aacgcgtgga cctcggtttc tcctaccagc ttgccggggg
     9661 aacggatgca atcatggatc gcggattctt ccgcaatctc aagaacattt ggctcggatt
     9721 ggatattttc aacttgttcg acataaagaa cactagttcc tattattgga ttaccaatat
     9781 agacaaccac cagtacgcaa tccctaatta cctgaccgga agacaattga atattcgact
     9841 tatcgttgat ttttaaccac atgatttcaa aaatatgctt tttaaacata tccggatcat
     9901 gctgataaat attaacgaat tatttctcta ttaataaaaa gagtgtacct ttgccaacat
     9961 agaacaaaaa gcaatattaa attactaaat tattattgac atggaactta cacatatcga
    10021 acatttgggt atcgcagtaa agagcatcga agcttgcctg ccgtattatg aagaagtttt
    10081 aggactaaaa tgctacaaca tcgaagaagt agcagaccag aaagtaaaaa ctgcattctt
    10141 taaagtaggc cagactaaga tcgagttgct ggagccgaca agtgaagaca gtacaatcgc
    10201 taaatttatc gaaaagaaag gtgaaggtat ccaccacatt gcatttgctg ttcccgacgt
    10261 acaggcagca ttggacgaag ccgaatcaaa aggtgtcaag ctgatcgaca aagctcctcg
    10321 tggaggtgca gaaggcttga acattgcatt ccttcacccg aaatcgacat gcagcgttct
    10381 gaccgaactt tgcatgccgg gaaaataaga aacaatggac aattgagaat tgacaattat
    10441 ttgatgctat tcaattgtca attctcaatc gttaattgcc aattaaataa gttcatttct
    10501 aacaacaaat ctatagtaca atgagtaacc aacttgaaaa agtaaaggag cttatcgccc
    10561 ttcgcgaaac agctcgttta ggtggtggag aaaaaagaat cgaatctcag cacaaaaaag
    10621 gtaaatacac cgcacgcgaa cgtattgcca tgttgctgga tgagggaagt tttgaagaat
    10681 tcgatatgtt cgtacaacat cgttgtacaa acttcggtat tgaaaaaact aagtatttgg
    10741 gcgacggtat cgtaacaggt tacggaacga tcgacggacg tctggtatat atttatgctc
    10801 aggatttcac cgtgttcggc ggtgctttat ccgaagcatt ggccatgaag atctgtaaag
    10861 taatggatca ggccatgaag atgggtgctc ccgttatcgg cttgaacgac tcgggtggtg
    10921 cacgtatcca ggaaggtgtc aacgccttgg ccggttatgc agaaatcttc caacgtaata
    10981 tcttggcttc cggggttatt cctcagattt ccggtatctt cggtccatgt gccggcggtg
    11041 cggtttactc tcctgccctg acagacttca atatcatgac ccgcggaaca agttacatgt
    11101 tcctgactgg tccgaaagtt gtaaaaacag ttacaggcga agacgttaca caggaacaat
    11161 taggtggcgc aagcgtacat acgaccaaat ccggtgtggc ccacttcgca gtcgatacgg
    11221 aagaagacgg tttacagttg atccgcaaat tgatcagctt cctgccgcag aacaacctgg
    11281 aagaaactcc tctgatcgaa tgtaaagacc cgatcgaccg tctggatgac aacctgaacg
    11341 acatcatccc tgacaatcct aaccaggctt acgatatgta tgaagttatc ggaaccatca
    11401 tcgataacgg cgaatttctg gaagtacatg ccgactatgc caagaacatt atcgtcggtt
    11461 tcgcccgttt taacggccag actgtcggta tcgtagccaa ccagccgaaa gtaatggcag
    11521 gctgtctgga cagcaacgcc tcccgcaagg caggccgttt cgtccgtttc tgtgatgctt
    11581 tcaacattcc tttggttaca ttggttgacg taccgggatt cttaccgggt acaggccagg
    11641 aatacaacgg tgttatcctg cacggagcca aattgcttta cgcttacggc gaagccacag
    11701 tgcctaaagt aactgtaaca ttgcgtaaat cttacggtgg tgcctattgt gtgatgagct
    11761 ccaaacatct gcgtggcgat atgaactacg catggccgac agccgaaatc gcagttatgg
    11821 gtccaagcgg cgctgtagaa gtgatctttg caaaagaagt ggctgcctcg gaagatccga
    11881 aagcttgcgc tgcagaaaaa gaagccgaat acaaaaaagc atttgcaaac ccatacaatg
    11941 cagctcaata tggctatatc gacgatgtta tcgaacctcg taacactcgt ttccgtatta
    12001 ttcgtgcttt acaacaattg cagaccaaga agttaagcaa tcctgccaag aaacatgaca
    12061 atctgcctct ataattctta aaacaggaaa tgaatatgat taataagaaa ataggggtat
    12121 tgctgctgtt tgcgttgctc gtttcattcg gggcaaaagc acagcgtgca acctccatgc
    12181 gaataaatga agtgctggtc atcaacgaag ataactttgt tgatgattac ggcaaacgcc
    12241 atgcctggat cgaattgttc aacaattcgg ccggttcggt caatatcgcc ggttgctact
    12301 tgactaatga caagagcaac ccgaaaaaat atccgattcc gaagggcgac gttctaacag
    12361 taattcctcc tcgccagcac actttgttct gggcagacgg agaaccggat cggggaacat
    12421 tccatgtcaa tttcacgctc gacccatcaa aagaaaatta cattgcgtta tacgatgcag
    12481 acggtaaaac tctgatcgat gagatcgtta tccctgcttc acaaaaagca gatgtcagct
    12541 atggtagaac tttagacgga caaggtgaat ggactgctct gacaaaagtt acacccagca
    12601 ccaataacgt aacattggat tctaacgaga aaatcgagaa ctttaaagaa aatgattctt
    12661 ggggtatcgg tatgaccctg actgccatgg cagttgtgtt ctccggatta ttcctgttgt
    12721 tcatcatctt taaacaaatc ggaaagctct cgatcgcggc cagcaaacgc aatgcacaga
    12781 aagcggccgg agcggctgtt attgcagaca atgcaggtca ggaatccggg gaaatctttg
    12841 cggctatcgg tgcggctcta tacgaaatga gcgacgacaa ccacgacatc gaacatacgg
    12901 ttctgacgat ccgcaaggtt caaagatctt attctccgtg gagttccaag atttacggtc
    12961 tgcgtgaagt tcccaaaaag taattatctc taaaaacaaa caagaatgaa aagttttaaa
    13021 tatactatta acggtaacgt atataaagta catatcagct cggtagtgga tgacatcgct
    13081 gaagtagaag taaacggtac tccctatcag gtaaaaatgg agaaaccggc aaaaaaacag
    13141 atggttacac tgaaacgccc ggctcaagct cctacaacgg caagtggcga accggttatt
    13201 tcccgtccgg cagcctcaac caccaagggc gctgtcaaat ctccgctgcc aggtgtaatc
    13261 ctgcaggtta actgtaaagt cggtgatact gtcaagagag gccagaatct acttgtcctc
    13321 gaagccatga agatggaaaa caacatcaat gccgaccgtg acggcaaaat cattgaaata
    13381 aaagtaaaca aaggggattc cgtactggaa ggtgctgacc tcgtcgtaat aggataatat
    13441 tatgttagga tcagtattat tacaggcagc gggtacggct catgaaagct ttctccagtt
    13501 cttgggagaa aacttggagt tgttcctcac ttatacagga gtctacaacg cgacaccggg
    13561 tcaccttatc atgatccttg tcggtctgtt gttcatcttc ctggctatta aatatgaatt
    13621 cgagcctatg ctccttatcc ctatcggatt cggtatcctg atcggtaaca ttccgttcaa
    13681 agatgcagga ttgcaggtgg gtatttacga acaaggttct gtgctgaaca tcctctacca
    13741 gggtgtaacc tccggatggt atccgccgtt gatcttcctc ggtatcgggg ccatgaccga
    13801 tttctccgca ttgatctcca atcctaaact gatgttgatc ggtgcagcgg ctcagttcgg
    13861 tattttcgga gcatatatca tcgctcttca aatgggattt gaaccgaacc aggccggtgc
    13921 aatcggtatc atcggtggcg ccgacggccc gacagcaatc ttcctttctt ccaagttagc
    13981 tccgaacttg atgggtgcta ttgcagtatc agcatactct tatatggcgc tggttcctat
    14041 tatccagcct ccgttcatgc gcctgctgac gactcagaaa gaacgtctga tccgcatgaa
    14101 accgccgaga gccgtttctt ccacggaaaa gatcgtattc ccgatcgtag gcttgttgct
    14161 gacttgcttc ctagttcctt ccggtctgcc tctgttgggt atgctgttct tcggaaattt
    14221 gttgaaagaa agtggtgtaa cacgtcgttt ggctgaaaca gcccgtggtc cgctgattga
    14281 tacaatcacg atcctgttag gtattacggt aggtgcttct actcaagcaa cccagttcct
    14341 gacattgaac tccatcaaga tcttcggttt gggagcgttg tcattcgtga tcgcaacttg
    14401 tgcaggtatc ctgttcgtga agttcttcaa cctgttcttg aaagaaggca ataagatcaa
    14461 tccgcttatc ggtaactccg gtgtgtctgc cgtgcccgac tctgcccgta tctctcagaa
    14521 cgtaggtctg gaatatgatc cgaccaacta cctgttgatg cacgccatgg gtccgaacgt
    14581 agcaggtgta atcggttctg ccgtagcagc cggtatcctg ttgggattct taggataatt
    14641 cacttattct acataaaaag gagctgaact ccaagtcatc tccaaatata aaaacttacc
    14701 caagtttacg gactttaacg tattcttggg taagtttgta tatgcgcaca acgattcatc
    14761 agaagtatat taatggctgt atcataaaaa actatttacg acacagcctc cctttttata
    14821 tccgacctta tcagatattt tgttcgacgg tcatcggatc tgtctctgga tttgcctcct
    14881 gttccaatgt tgtccccaaa aacaaccaaa tcattaacag gataatcgcg atcaccacac
    14941 caaagaccag cagtacattc gtattctttc gtctcatgtc cattcttcaa tattgatttg
    15001 aagattaaac aagacacccc cttttttggt ttaaccgttc cttacttttg ttctttattt
    15061 aactgagtaa atattttaga aagaatgttt ttttcttcac ttacaaatac aattggaaat
    15121 agacgatcca actatcatac catcataatt ggcaataacc cactatatat caacacaaaa
    15181 tagccatgac agttcgcaaa acaactgtca tggccactat cataccatca tacataaaat
    15241 tagtcaatca attatatatc aaccatctac ctcttccaca taataacaag tccccctcat
    15301 cgtccgctta ttcggcacac tattccgctt caaaagcttg ccgaaattaa ggatcatcgt
    15361 ttttgtaatg ttaaaaccag gttgtttctc cgcgatcata tccagtatct cggacgccag
    15421 aagcggcttt gcctcttcaa tatcctccgc gatcttgaaa taacgcagga acagttgctc
    15481 ttcagccggc tgctgctgga aatccctgtt gttttcagtg atcagcgcct cttcctccgg
    15541 agtaaaccaa aaacgttcac cacgcctcaa caattctttc gcttccgcat acaactgatc
    15601 ataatcgatc ggctgggcat aatcgatccg gcccttcacc tccacgcaaa tgaagcggcg
    15661 gctaccggtc ggatccgtca gcaaatcata attgttgctg gtcgcgataa acgtggcata
    15721 gcgacgcaag ttacggctcg cgctctgata aggcaaacgg gtgttcacaa ccgctttttg
    15781 caggatatgc ttcaaaaaac tttgatgaga acttttcact gaatcaaatt catcgatatt
    15841 aatcaacgca taccggtgca aagccaactc cgccccacga cgattgccga aatcgatact
    15901 gtccgtataa taaggacgca acactggtgg caacaaattc aagcaaaacg tggacttccc
    15961 acacccttgg ccaccgacca acagaggtgt cgtactattc ccgtgttccg aatccagttc
    16021 catccaatgt gctaccatgc ttaggaacca gcggtaaaac aaatctcccc atatcggatt
    16081 gtcacaaggg acacgcccgg ctaatgccct gatgcgttct tttccgtccc aagccggaag
    16141 attcccaaga aaatgatcga taggatgata tatcggaaca cgatcggaat tgacataccg
    16201 gtcgatatcc ttgtcccata cattcaaccc ttcctgctgg gcttccaggc aaatggaatt
    16261 ccgaactttc gtcgtataag gcttgtaaac gaactgtatc atcgaacggt ccaaatattc
    16321 cactccaccg ctcatctcat tcgtccggaa gaaataacgc cggttcataa actcgtccaa
    16381 ccgcaacacc aacgacatgg atggcgggac ggaagagagc ggctccgccc gatttgaaac
    16441 attctccaac gtatatgccg tacggaaagc catacggacg tctatcttat attttttcaa
    16501 agcctcatag cgcaatgtcc agcctaccgc ctcttcctcc ggtattccaa gccggcagca
    16561 agcctgcgcc aagtcgatga acagcagttg gatatcatct tccgggcttt ctgaaaaccg
    16621 gcgcgtcatc tccatcagga tgacactgaa cagcgtggcg atctgcccgt tccgatccgc
    16681 tcccggagcc atcatctcca acggatcccg aaccggagaa ggcacgatct tcaagtcacc
    16741 cccgtccggc atctgcaaag gttgctcgat ccggatcgcc accgcatccg gattgtaata
    16801 ggcgtccgga tccacactca tccggcaccc ccgcgacagg aacggttctt tcaacgatat
    16861 aatgctgccc aactgcggct ggtaatgccg caccgccagc tgataagccg cagcatgaaa
    16921 catacgggcc tgctcctctt ttttcggcag cgagccgtcg ggcagcacaa aaggaaccac
    16981 gatcttgacc gaacgcccgc tcagcccgac gaacgccagc aaggtctgcg gcagggcggc
    17041 agcttcacgg cggacggcct ccgcctcact ctggctttcc aagccgttca cttccaacaa
    17101 gacatacccg ttatagcgcc tcaactgtat tccatcgcca ttcttcttga acgtcgagcc
    17161 aaaagccaga accggtagtt ttccggacaa atccgtggtt cgtgccaaaa acgccatatt
    17221 caattttcga cgaaccgaca gtatcgcttc cgcatctttg ccgtttttca gcaacccgac
    17281 aatatattcc atatcacgcg agtgcatccg caacacgcct tttttatgcc tgtaatatgt
    17341 gatttgcatt accaaggatt tctttcgaat ttgacaaatt tcatgctctt tctcacacag
    17401 ggagccatcc tgaaacagac acgacgcgcc ttcacccgat ggggagtaca ttttttcgga
    17461 tcttcgaagc cttcgctccc tgccgaaaga taaaaatcac ccaacccgtc caactccacg
    17521 gaatagccgt ctttcaacaa ttcaagaatc atccctccga tctcgcaaac cgaagcgaac
    17581 acatcacctc ggctcaacga gcaacgatcg gcaaccaaat cagccagctt tttcgttgaa
    17641 acccgcccgc acgtaaccgg aacaccataa tagcgtactt tatcttccgc tcccgtcttg
    17701 tccagttttt gccggactac atagtaatgt gccataaata acagtatttt taatattaaa
    17761 caaccagata ttcttcttaa gacgcccatt ttaacacttt tgacaccccc atctgaacgg
    17821 tatcaacacc cgggtctcac cccttccgac acccggatga cgggcttctt ttcttattac
    17881 aaatatacaa ataaaacatc tataatgcaa atatttacag cactttattc aattatatct
    17941 acacttattt ttccccagca cgaagacaga agcatgtgat atacgacatg atagtatgat
    18001 agtatgaaat gatagttgaa aatagatact atcatatttt tataaactaa tatacagaca
    18061 tttataagaa aatatgatag tatgatagtt ggatttaaaa aaaatcatat gtatataata
    18121 ggtggatgtt tacagcagct tatttatatt gcttgcagga ggaagactta catggatggc
    18181 aaccctaaat aacacatcgt cctgtttcca tgtttgacat tgcagctatc aaacacaaga
    18241 aacaggacga ttttgcatat ctaagttctt ttccgattga ccggacttac ataaaaattt
    18301 cgacaaacgt gccattccga catagtacac aactacatca tcgagctaaa agcaccttat
    18361 tttttgcaac cgtcgcctga aactctttca ggtagaacgg ttcgaaatag gcggtgtctt
    18421 caaacttgcc ggcggcaaaa gcttgttccg agagcggaat catgtttacg gcaagaggat
    18481 ggatgtcctc gataaagatg gcattcggag aagtgatgac cgatttgcat ttggaagcac
    18541 cgttgccaaa gaaacaaact ttcccttttt ccagataaga agcatacgta ccgacttcca
    18601 caatatcggc cttcgtctcg cggacaggct ttaaggaagc atcgtagata gcggcataaa
    18661 cctccatacg ccgggcatcc aacatagcac aataaaggca atcatcagta atagagacga
    18721 tttgcgaatc gcccttactg ttgacagtag cagccatgat gtccaacgta tgaatgccga
    18781 tcagaggaat accgaaacca aagcaaagac ctttagcgac agacactccg atacggagtc
    18841 cggtataaga accaggaccg ctactgaccg ctacggcatc caaggctttc ttccccttct
    18901 ttttcaatac ggaaagagct tcttcaacaa atacgcctaa tagggctgca tgcgaagggc
    18961 cgtcgaacga ggccttcgca aaaaggactt caccatccat agacaacgct acagagcata
    19021 cagaagtcga tgtttcgata tttaatatac aagacatttt aattgacaat tgacaattga
    19081 caattgacaa ttaaaatatg tgtcaaaagc caatcggttg ataatggatg caaaagtata
    19141 aaacataact gtaatctcat gatcaaaacc gattttatta aggctgacac ggatggtttc
    19201 ggctttttct caattatatt gtcaatcgtc aattgtcaat tatcaattga ttagctatct
    19261 ttgcacaaat ttttagaaca atgatacaat caatgactgg attcggtaag gttacagccg
    19321 aacttccttc taaaaaagta accgtagaaa taaaagctct gaacagcaag caactggatt
    19381 tgtcgacccg cattccttcc atctacaaag aaaaagaaat gcaaatacgc agtttgttac
    19441 tccagtcgct tgaacgtgga aaagtcgaat ttaatatatt tgtcgaatat atcggtaaag
    19501 acacgcccac acagatcaac ttggctgcgg tagaaaacta ttacaatcaa atcaaagata
    19561 ttgccgaccg cctgaacatc ggacttcccg ccgactggtt ccagaccctg ctccgcatgc
    19621 cggacgtgat caagacagag gcccaggaag taaacgaaga ggaatggaat gtggttgaga
    19681 aagcgatcaa agaggccata gggcaccttt gcgatttccg tattcaggaa ggcgccatgt
    19741 tacaaaagtt gttcgaacag aaaattgcca atatctcccg cctgctttca gaagtagaac
    19801 cgtatgaaaa ggagcggatc gaaaaaatca aagcccgtat catggacaat ctcgaaaaga
    19861 ttgccggaca ggactacgac aagaaccggt tcgaacagga gatgatctat tatatcgaaa
    19921 aactggatgt aaacgaggaa aagaaccgcc tggacaacca cctgaaatat tacatcagca
    19981 cgatggagag cggacacgga caaggtaaga aactcggttt catcgcccag gaaatgggac
    20041 gtgaaatcaa cacccttggt tcgaaaagca accatgccga gatgcaaaaa cttgtcgtcc
    20101 agatgaaaga cgaactggaa caaatcaaag aacaagtatt aaacgtatta taaaaacgat
    20161 atatggctgg caaactgatc atattctccg cgccgtccgg ttcgggcaaa tccactatca
    20221 tcaatttcct gctgaagcag aatctgaacc tgcatttttc catctcggct accagccggg
    20281 ccccacgtgg tacggaaaag gacggagtgg aatattattt ccttacaccg gatgaattcc
    20341 gtgcccgtat agcagcagga gattttctgg aatacgaaga ggtctatacc gacaaatatt
    20401 acggcacgct gaaaagcgag gtggaacgaa ggctgatgag tggcgataac gtcatattcg
    20461 atgtcgatgt cgtaggaggt tgcaacatca agaagtttta tggcgaccgt gctctttcgg
    20521 tctttatcca gcccccttcg atcgaagatt tgcggagtcg tctggaagga cgcggtacgg
    20581 atgctccgga agtaatcgaa agccgcattg ccaaagccga atttgaactg ggttttgccg
    20641 acaaatttga cgtaatcgtg gtgaacgaca agctggaagt cgcacaaaaa gaagcactaa
    20701 aagtgataaa agagttcctt aaaaaagcat gaacggcaag aagttatcca agaaatggct
    20761 atatacattc attggtatag catttgtcgc tcttgccact tgtacagccg ccctatatta
    20821 taaggagtat atcatagcga ccggtaccgg attggtattc ggtgcacaag tcataaatat
    20881 catcaagtgg aaacgggact gaaagaaaat acggtcagca aacgtaaaac cggcatttat
    20941 tccggttcat tcaatccggt tcatatcggc catctggcat tagccaactg gttgtgtgaa
    21001 tttacggagc tggacgagct atggtttctg atcacccccc ataacccgct aaaagagaag
    21061 gaagaactga tggatgaccg gcttcgctat gaactggtta aaaaatccat cgctggttac
    21121 cctaagttcc acgccagtga cttcgagttt tctcttcctc aacccactta taccatcaac
    21181 acactccgga cattggaagc aagttatccg gaccgtgaat tctatttcat catgggtgcg
    21241 gacaattgga aatatattac ccggtgggta gaatacgaag ccatcatttc caattatccg
    21301 atcttcatct atccgcgtaa aggattcgat gttgaaattc cggcacaata tcctcacata
    21361 aaaaaagtag acgccccttt ggtcgaaata tcctcaacct ttatacgcga agctttcaag
    21421 accggaaaag atgtccgctt cttcctgccc gaagccatac gtaatctgcc ttttccatta
    21481 caaaacaata ccttttaaga acataaagcg taaagtcgca tacgttttta ggcaataagt
    21541 aagaaaagtt ttgtattttt gcgccgtatt atacaaaata atagcgtaat gaatctatta
    21601 gaactgagtg aacaggaaat cataagacgt aacagcatgg agcagttacg tcagatgggg
    21661 atagaacctt atcccgcagc tgagtatgta acgaatgcat tttccaaaga gataaaagag
    21721 aattttaaag acgatgcaga gccccgcccc gtaagtattg ccggtcgcat catgagccgc
    21781 cgcatcatgg gaaaggcttc cttcatggaa ttgcaggatt cagaaggcag aatacaggtt
    21841 tatatctctc gtgacgacat ttgcccggaa gaaaataaag atctgtataa cattgttttc
    21901 aagaaattgc tcgatatcgg cgactttgtc ggaatcaaag gtttcgtatt ccgtacacag
    21961 atgggcgaaa tttccgtcca tgcacaagag ataacggtat tatccaaatc actcaagccg
    22021 ctaccggtcg tcaaatacaa agacggtgta gcatacgatg gattcaacga tccggaattg
    22081 cgttatcgcc aacgctatgt cgacctggtg gtcaatgatg gcgtaaagga tattttcatg
    22141 aaacgtgcgg cagttatcaa gaccatgcgt accgccctgg acgaagctgg atatacggaa
    22201 gtggaaactc cgatcctgca atccatcccc ggaggggcaa gcgcacgtcc gttcattacg
    22261 caccataact cgctggatat cgacctctat ctgcgtattg ctaccgaact gtatctgaaa
    22321 cgattgatcg tcggaggttt cgaaggtgtc tacgaaatcg gtaaaaactt ccgtaacgaa
    22381 ggtatggatc gcacccacaa tccggaattt acctgtatgg aactttatgt ccaatataag
    22441 gactacaact ggatgatgag cttcaccgaa cagctgttgg aacgtatctg tatcgccgtc
    22501 aacggtacat gtgaaagtgt agtcgacggc aagaccatca actttaaagc tccttaccgc
    22561 cgtctgccga ttttggatgc catcaaggaa aagacaggtt acgacctgaa tggcaagagc
    22621 gaagacgaga tacgcacgat ttgcaaggat ttgaaccttg aaatcgatga aacaatgggt
    22681 aaaggcaagc tgatcgatga aatcttcggt gaattctgcg aaggtacgtt tatccagccg
    22741 actttcatta tcgactaccc ggtcgagatg agtccgctaa ccaagatgca ccggagcaaa
    22801 cctggattga ccgaacgttt cgaattgatg atcaacggta aagaagtggc aaatgcctat
    22861 agtgagctga acgatccgat cgatcaggaa gagcgcttca aagagcaatt gcgcctgagc
    22921 gaaaaaggag atgacgaagc gatgttcatc gaccaggact ttttgcgtgc actgcaattc
    22981 ggtatgcctc cgacgtctgg tatcggtatc ggcatcgacc gtctggtgat gttgatgact
    23041 ggccaaacga ctattcaaga agtgttgctc ttcccgcaga tgcgcccgga aaagacagtt
    23101 aagaaagaca ccgcagacaa atatgtcgca ctgggtatcg atgaagcatg ggttcctgct
    23161 ttacataaag ccggatatct cacaaccgac acgttggtag atgctaatcc caacaagctg
    23221 agacaggaac tctgcgaaat gaataagaaa tacaaactgg aattgcaaaa ccccactgcc
    23281 gaagaagtag aggcatggat tgcaggcgca gccaaataag agtaatacta tgaagttgcc
    23341 cggaaaaatt gcaataatgg gaggtggtag ctgggctacc gccttggcca agattgtact
    23401 ttctacacaa gatagtatta actggtatat gcgtcggcca gaccaagtag aagagttttt
    23461 gttgttggga cataacccca gctatctttc cgccgtcaaa tttgatactg acaaaatcaa
    23521 attctacacg gatatcaaca aagtaatcaa agattcggac actttgattt tcgccacccc
    23581 ttctcctttt ttgaaacaac atttgatgaa ggtgacgacc tccatgcaag acaaattcat
    23641 catttcggcc atcaaaggaa tcgttccgga cgaaaacatg ctcgtagccg attattttgc
    23701 cgaatactac aatgtcccga ttgacaatat cgctgtcatc ggcggtccgt gccatgccga
    23761 agagatcgct ctcgaacggt tgtcctatat cacgctggct tgccctaata tcgagaatgc
    23821 aagagctttc tcctccgtat ttaagaacca gtatctgaac aactcctgtt gcaaggatgt
    23881 tacaggtatt gaatatgctt ccgtattgaa aaacgtatat gccatcgtcg caggtatctg
    23941 ccacggtatg aagtatggag ataattttct ggcagttttc atctgcaacg cgatcgaaga
    24001 gatgcgtaac ttcctcaacg ccgtacatgg cctggaacgg gatgtgacag attcggtata
    24061 tctcggtgat cttctggtaa ccgcatattc tcgcttcagc cggaaccgta cgttcgggac
    24121 catgatcggg aaaggttatt ccgtcaaaat agcccagctc gaaatggaga tgatcgccga
    24181 aggatactac gggacaaaat gtattcggga gataaacgaa aaatataaag taaacatgcc
    24241 gatcttggat actttatata gtattctata cgaaaagaaa tcgccgacta ccgcgatacg
    24301 gcagttgact gaaacattta aataataatg taaatatgaa gaacatcagt cttaacattg
    24361 acaaagcgct gggtaccgta acgaaagaac aggtatatgc tcaggctgca aaggcccacg
    24421 aatgtaatgc cactttacaa aatggaaatg gtgcaggtaa cgacttttta ggttggttgc
    24481 acctcccctc ttctattaca gatgctgaac tgacagacat cgaaaataca gctaacgtac
    24541 ttcgttctaa atgtgaagtt gttgtcgcca tcggtatcgg cggtagctat ttaggaacaa
    24601 aagcagtggt agaagcatta aacaatagct tcgactgg
//
