LOCUS       c00012_gnlPro..        13828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KMGAFAAA_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 14:00:53
            Original ID  :: gnl|Prokka|KMGAFAAA_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 14746
            Orig. end    :: 28574
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13828
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[24746:28236]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13828
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13828
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(467..1057)
                     /locus_tag="ctg12_16"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             complement(1195..2805)
                     /locus_tag="ctg12_17"
                     /transl_table=11
                     /translation="MQGFLCQGTDEVHIVGDEDQCSFIMLQSLHQGFYGQKVQVGGRLV
                     HQQEVGRIHQEFDQAEPRFFPAGKNADAFFHIQPPEQEGTQDGTRFFLPDFSAAFHDFL
                     QHGIFRIQVFRSRLGEVADARRGTGSALSGVNGDDARQDFEKSGFARAVRAYKNSALPA
                     FHQQVQVFINPAVAIGLADFFQLNDFLGAARRLGEVEFKYFPAGYRFLNDFHLFQLLDA
                     ALDLPGFGIDGAETVNKFLNVRYFLLLVAVGRLKLLEAHVLLLEEVRVIAAVFHQFFVV
                     DVVHAFHQLIHEIPVVGNHQDGSGVVFQVSLEPQQGQEVQVVGRFVQHQEVRLQDKELG
                     QVRAHDPAAGHFPGGAVEVAFPKGQPFENFLGFGLQLVTVGGVESVNGFRVFRRIRFVG
                     VFRRPDGVDGLFHFRRDAQGDFQNGFILRFAGFLGKIAHDGVFIHADGAFVRRVFSQNH
                     AEQGGFACSVGADQSHPFPPVNGHFRFPEQGPSGVGFCEIFDRQHGEERMYSTGMERGR
                     QEPSGRRQAFLKALLDFYA"
     CDS             2971..3489
                     /locus_tag="ctg12_18"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             3591..4364
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_19"
                     /sec_met_domain="adh_short_C2 (E-value: 1.3e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4745..5593
                     /locus_tag="ctg12_20"
                     /transl_table=11
                     /translation="MGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGR
                     PRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEW
                     LSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKK
                     PNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDS
                     LRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKGE
                     P"
     CDS             5607..5807
                     /locus_tag="ctg12_21"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWKYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             5860..6054
                     /locus_tag="ctg12_22"
                     /transl_table=11
                     /translation="MGPIAVLPKYQRRGIGRRIILYAAALQVCELQRGSLSGLKGRYVK
                     AAVYHMDEKRAAEFDGIFR"
     CDS             complement(6272..7012)
                     /locus_tag="ctg12_23"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAEGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7187..7276
                     /locus_tag="ctg12_24"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKRKCIH"
     CDS             7307..8014
                     /locus_tag="ctg12_25"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGIAFNGYGTNNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDFGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg12_26"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLVAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg12_27"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg12_28"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_29"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_30"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.1e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.9e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_31"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.7e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 ctgtaatgcc gtgacatgga acaagaaaat ctcttgattt ctacttgcca ccatttacat
       61 tggtgccagc aaacctccgt ggatgcggag gttccagtag ttaacaaaca ctgtatttaa
      121 ttcgaattat gaagaacatc gctatcctcg ccatcgccgg cgccgcttgc ctggtcgctt
      181 cttgctccca gcagcagcag caacagcaaa ccaccgctcc tgctcccgct ccggttgtgc
      241 aggccaaggg caagtaagtt tgcagcgggg ttttgccctg caacactagc aaattatcca
      301 attaatccgc actcggtgta cgcactgagt gcgtttttat ttgccctgag tccggattcc
      361 ctccgccatt tgccgattcg ccgggatttt ccttaaaaac ggcggatacc gcaaaccgcc
      421 gcggcgcagc accgtgtgcc ggttcctgcc ggatcaggct tcccctttat tcagcggccg
      481 ccttcgcctc attctgctga tcggactgaa atatccgctg aaccagcatg gggcgtttcc
      541 tggcccaccc gggccagacc aggtgatgtt ccatgccgta ggaatggccc tccggaaagg
      601 ccttggaaac aaatggttcc cgccagtcct cctcccattt gccgccttcc cggtccttct
      661 gggtcagcgt caccagatgc ccgcagttct tccaggcatc cagaacaatg gagccctgca
      721 atcccttccc cgcggcattg acatacacgc aactgtgctc cctgcccgtt ccacggtctc
      781 gaatcgtcag ccctatgcgg aaatacttca cggggcggcg gcgcaggtcc cggtacaaat
      841 cctgctggac ctgccagcac agccccctgt cgcgcaggtt ggaattgacc agaatattgt
      901 tcagccagcc aaacagcaca gtcctgttgt cccgggcaat cgctgcggac tggaccacgg
      961 ccgtgtccgc cagccacctg gcctccgctc cggcagcggg aagagaggcc tgatccggcg
     1021 gcagcagcgc caggaaggca ttagccagcc cggacatttg ctgctgcacg taagtttgtt
     1081 gtatataatc ctccgccgga ggagtacagc aggaactcca tccgcacaaa agggcggcag
     1141 caagcaaaag cctgaatgtc tgcgtggtcg gcatggcgcg ccaaggctag cagactacgc
     1201 gtaaaaatcc agtaaagctt tcaaaaatgc ctgcctccgc cctgacggct cttgccttcc
     1261 cctttccatc ccggtagaat acatcctctc ttcaccatgc tgacgatcaa aaatctcaca
     1321 aaatcccacg ccggacggac cttgttcagg gaaacggaaa tgaccattaa ctggggggaa
     1381 cgggtggctc tggtcggccc caacggagca ggcaaatcca ccctgttccg catgattctg
     1441 ggagaagaca cgccggacga aggctccatc agcatggatg aatacgccat cgtgggctat
     1501 cttccccagg aagccagcga accgaaggat gaaaccgttc tggaaatcgc cctgggcatc
     1561 acgccggaaa tggaacaggc catccacacc atccggacgg cggaaaacgc caacaaaacg
     1621 gatacgccgg aatacgcgga agccattgac actttcaacg ccgccaacgg ttaccagctg
     1681 gagcccaaag ccaagaaaat tctcaaaggg ctggcctttc gggaaagcga cttccaccgc
     1741 cccgcccggg aaatgtccgg cggctggatc atgcgcgcgt acctggccaa gctccttgtc
     1801 ctggagccgg acctcctgat gctggacgaa cctaccaacc acctggacct cctgtccctg
     1861 ctgtggctcc agcgatacct gaaaaactac cccggagcca tcctgatgat ttcccacgac
     1921 cgggatttca tggatgagct ggtggaaagc gtgtacgaca tcgacaacga agaactggtg
     1981 gaataccgcg gcaattactc ggacttcctc caacaaaagg acgtgcgctt cgagcagctt
     2041 caggcggcct accgcaacca gcagaaggaa atagcgcaca ttcaggaatt tattgaccgt
     2101 ttccgctcca tcaattccaa agccgggcaa gtccagagcc gcatcaagca gctggaaaag
     2161 atgaaaatca ttcaaaaacc ggtagcccgc aggaaagtat ttaaattcaa cttcccccag
     2221 cctccgcgca gcacccagaa agtcattgag ctggaaaaag tctgccaatc ctatggcgac
     2281 cgcagggttt atgaaaacct ggacctgctg gtggaacgcg gggagcgcac tgttcttgta
     2341 ggcccgaacg gcgcgggcaa atccactctt ctcaaaatcc tggcgggcat catccccatt
     2401 gactccggac aacgcactcc cggtaccacg acgcgcatcg gctacttctc ccaggcgcga
     2461 acggaaaacc tgaatccgga aaataccgtg ctggaggaaa tcatgaaatg cagcgctgaa
     2521 atccgggagg aagaagcgcg ttccatcctg ggttccttcc tgttccggag gctggatgtg
     2581 gaaaaacgcg tcagcgttct ttccggcggg gaaaaatcgc ggctcagcct ggtcaaattc
     2641 ctggtggatc cgcccaacct cctgctgatg gacgagccga ccacccacct ggaccttttg
     2701 tccgtagaag ccctggtgca ggctctgaag cattatgaag gaacactggt cttcatctcc
     2761 cacgatgtgc acttcatccg ttccctggca caaaaaaccc tgcatgtgaa ccgggggacc
     2821 atcaccgcct acgcaggcgg atatgactac tatctggaaa agtcaggcat tctggacgat
     2881 gaaaaaggcg gcatcacggc ggaataaggc tcttttttca gtttcccctt tttccttgcc
     2941 gtggatttca tcctgcctta aaagaacagg atgaaggctt ttcttgttcc tctcttatat
     3001 tctgcgcttc tgtccggagc ctctcttgca tttggtgaaa cggccgccgg aacggcttcc
     3061 cccgcagcag cggctccggc ggaaaaaatt ccttccgcgg aatccctgat caaccaggcc
     3121 ttttcctttg ccatcaatat ccagcagacg ttggcaggcg ttcaggacaa ggaaagcgcg
     3181 gacaacgccg tcaaaacgct gcaggacatt cagaaggaca tccggcattt cctccagctt
     3241 caggataaat tgaacgatgc ggaaaaggag aaagaagacg ccttgataga aaaaatggaa
     3301 aaacgaatgg aaatgctgga caaccgctgc aggcaggaag gcaaacgcct gtttgaggcc
     3361 cgctattacg gttccgccgc cttaaaggac attttggaaa attcggatga attcagcgac
     3421 ctggtagaac cggatgaaga cggggcgccc cccggtgcac tccgggaaaa tgaagaggcc
     3481 ggacagtagc cccccgcccc gtttctcccc ccctcttttt tcattcccgg cacgcccctt
     3541 ccccgtatgg gttcctgcgc ggccaagtcc atttcaagct tgccggaacc gtgaaaaacg
     3601 ggtttactgt gggcagcatg caaaagttag caggtaaaac agccatcgtt accggcgcgg
     3661 gccgcggaat cggcaatgcc gtcgcgcgcc gcttcgcttc ggaaggagcc agggtcatcc
     3721 tgatcagccg cagtccatcc agctgcgggg gggccgcaga agaaatcaac aaggaatttc
     3781 cggattcctg caaggcctac ccctgcgacg tagcggatta cgcggccgtt caggaaacca
     3841 tggccgccat tttgaaagac ttcccgcaga ttgacatcct ggtgaacaac gccggcatca
     3901 cgcgggactc cctgatgctc cgcatgaagg aggaagactg ggatgccgtt ctggacacca
     3961 acctgaaaag cgcgttcaat acggtcaagg ccctccagcg cgttctcatg aaatccccgg
     4021 ccgggcgcat catcaacatg agctccgtca tcggtctcgt cggcaacatc ggccaggcta
     4081 attacgccgc ttccaaggcg ggcctcatcg gtttcaccaa atcactggct caggaattcg
     4141 ctccgcgcaa agtcacgtgc aacgccattg ctcccggctt catctccacg gaaatgtcca
     4201 atgccattcc cgacaatctc aaggaagaaa tcgttaagaa aatacctttg aaagaacaag
     4261 gttccgtgga agatatcgcc gccctgacgg ccttccttgc ctctgacgat gcccgttaca
     4321 tcaccgggca ggtcattgcc tgcgacggag gcatgacgat gtagggcatt ccggttttct
     4381 ccattccatg cgcggcattt tccttgtttc ctgctttctg ggaggaagcg ccctgctggc
     4441 cgggtgccgg gaagaaaata attccccccg cccggccacg gaagatgccg cgcgcattac
     4501 cagcgcacgc cagtggggag aaagccgatc cgcgctgcaa aaacgggaac tggaccgcgc
     4561 tgccggtcct gcccttccca ttccggatga cctgccgtcc cgggagctgg tcggcacaac
     4621 gcgccaaatc catcagctca ttgaagcttc cggaaatccg gcacgttttg aatcctacac
     4681 ggaaacggtt cccgtggcgg gagcttccct gcgcatggtc gccataccgg gaggaacgtt
     4741 cctcatgggg agtcccgcgg aagagccgca ccggaaaccg gacgaaggtc cgcagcataa
     4801 agtgagcatc tcccccttct ggatctcgga aacggaaatc ccctgggaac tttatacggc
     4861 cttcatggaa aacgggcgtc cgcgcgccaa ggacggccag cttctggagg aacagccgga
     4921 tgacgaactg tgggactccg ttacgcagcc taccgccccc tacaccgcca tgaacctggg
     4981 catgggccac ggctatgaac acggtctgcc cgccatctcc atgtcccacc acgccgccag
     5041 caaattctgc gaatggctga gcgcccagac cgggcattac taccgcctgc ccacggaggc
     5101 ggaatgggaa tacgcctgcc gggccggctc ccccggcgcc tattcttacg gaaacgggga
     5161 agcctctctg gaccagtacg cctggtactg gaacaactcc aatgaccgct accagaaaac
     5221 aggctctaaa aaaccaaata agtggggact ccgggacatg cacggaaatg tggcggaatg
     5281 ggttttggac tcttacgttc cggatgccta cggcaaacgg agcggcttgc ccgcgaaaga
     5341 ccccctggtc atcatccccg gcgcccctca catcgttcgc ggcggttcgt gggaagacga
     5401 cccggacagc ctgagaagcg ctgcgcgccg cgccagcacc cccgcctgga accgtcagga
     5461 tcctcaaaac cctaaaagca tctggtacct gacggacgga ggcatgatcg ggttccgcgt
     5521 ggtgcgcccc atgaacattc cggacattat gacgatgcac cgcctctgga atttctccaa
     5581 gggggagccg taaagaacaa cctttcatga ccattgcatt aagaacggaa caatcctcag
     5641 accatgccga aacggaacat gtcacgagag aagcgttctg gaaatatttc gtccccggct
     5701 gccatgaaca ttacctgctc catatcatgc gcgtcagtcc gtccttcatc ccggagctgg
     5761 atgcagtcgc cgtccacggc agccgcatcg tcgggaaaca tcgttgatgc aacgtccgtc
     5821 atcagggcag acgatggaaa agaatatgaa gtgctgggca tggggcccat tgccgttctt
     5881 ccgaaatacc agcgccgggg aataggacgg cgaataatat tgtatgcggc ggccctccag
     5941 gtctgtgagc tgcaaagggg ttccctatcc ggcctgaaag gccgctatgt gaaagctgcc
     6001 gtgtaccata tggacgaaaa gcgcgctgcc gaatttgacg gcattttccg gtaaagaaaa
     6061 agctttccgg tactgcgtct caaaaacgtt tccagcaaat tgccgccatg ccgaaaaaac
     6121 cggatacggc cccctgcccc cggaaattcc gtaccttccg gagggcatga atcccgcata
     6181 cggataagca attcttcctc tctggatata aaaaacaaga gctgttccgc aagaacagct
     6241 ctcatccgcc gatttttcgc catcaggaag ctcaagccct gcggcggcgc atcatcagcg
     6301 cggccagtcc cagcaggccc agggaaaccg tggctggttc cggcaccatt tcccctcgga
     6361 tttccgtgaa aatcggggat aataagctga aagtattggt tccgttggct cccgtaataa
     6421 cgacagaatc accaggcgct ccctcggcgt cataatggcc gcggatgccg ggagcagtca
     6481 atccgccgct gatcgttacg gtatctcctt ccgtgttagc agtaggggcg gctgttccct
     6541 ccgcagcata taaatacgtt ttagacgtat cctgcatcaa gtccatcacg gactggctca
     6601 cggccaggaa acggtatgtc aatgccgcgt caagaagcag gggagaacca tccagggaag
     6661 aaaaactgaa cgtcagatta atccctgctg cagtagttcc cgtattggtg ctccagccga
     6721 tgaccgaatt gtcggagcca ttcagcacca ggaagccgta agtgacatta gcgcccaaat
     6781 tgttggcggc tccgcgcagc gtaaaactgt ccagtctgat ctctccggac agggaggagg
     6841 gagaagagga atcggaagga gccagggaag aagaccccag gccaagataa aacccatgga
     6901 tggtactatt gtaattatcc gtaccgggag tgtaataatt aaaaacggtc gctgcctccg
     6961 aggaaacagc aaagcttccc atcgcgatta aaaatgtcag tgttttcttc atatttatta
     7021 ttccttttgg atggcaactt gtagcgaatt tggaattccc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gattgccccg
     7141 tcatcttgac aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaata
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagcg
     7261 caagtgcata cattgaatct tgcatcattt tattaagata ctgaccatga agaaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctgagcgcc accgcgaata ccactctgct
     7381 ggatagctct atcgtgggat attcggactt tacctcccaa acggcggatt tcggcaccct
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggatagcctt
     7501 caacggatac ggtaccaaca accgcgacgt tatgtctgtg acgatggttc ttgatctgtc
     7561 caaaatcaac actccggacg cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 cagcgggccc gtcgttgaca ccccgctggg cacggaaggg tccctgacca tttccgtagt
     7741 caccggagat tttggcaccc gcatctattt tggagacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcaact
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 ggccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatggca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa caacccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggtcgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgccg
     8701 cgggcggaac taacgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcaactc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgctg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagtc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatca aggcgacgct
    10321 ctcctcccgc tacatgatct ataccggcct gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgttggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggg tgcaacgtca ctgccgccta caaagcctac aagcgtggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaaaggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaagaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca tgtcctcggt gaagccaact tctccgacca
    12061 cggagccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaaa cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcttt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attcctcacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgt ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggcttcggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 caggtttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga gaccgtactt ggcaatgccg
    13681 gacgaaacct aagcaggccc cgtccgacag cgacggcccc atctttctcc gagaaagaga
    13741 aacattgatt acaggaattg gactgatgcc cggaagggat ggcctcctgt caagggctca
    13801 gcatgagagg aaaacatttt ctaacaaa
//
