LOCUS       c00008_gnlPro..        13472 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBPAGIDJ_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:58:15
            Original ID  :: gnl|Prokka|PBPAGIDJ_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13472
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13472
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3472](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3472
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13472
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13472
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..3472
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="PFOR_II (E-value: 2.3e-18, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.2e-81, bitscore: 263.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.6e-31, bitscore: 100.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 9.4e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.5e-08, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.2e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.7e-25, bitscore: 78.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AAIYPITPSSTMAEYVDEWAAAGRKNIFGETVLVQEMQSEGGAAG
                     AVHGSLQAGALTTTYTASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQ
                     DVMSARQTGFAMLAEGSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLE
                     NDDLAPLIDQEALAEFRARALNPMKPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEY
                     MNEISKITGRKYGLFDYYGAEDAERVIIAMGSVTEAAREAIDYLVANGEKVGMVAVHLY
                     RPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGL
                     GSKDTTPAQILSVFENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYG
                     LGADGTVGANKNSVKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDNPIRSTYLVNT
                     PNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYY
                     INATQIALEIGLGNRTNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKN
                     YAAVDRGGEYKTLAVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGI
                     EDGTWYQGTAKYEKRGVAAFVPEWNPENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKF
                     EQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLAQAEN
                     WTYCAENVKTKQHLVDIKANVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMV
                     ANATGCSSIYSGSVPSTPYTTNENGHGPAWANSLFEDFCEFGLGMELANEKMRARLVKV
                     MNEAIAADCTPAEVKELFAEWINNMLDADKTKELAAKIIPVVEANKDKCNHCKQIAELQ
                     QYLVKRSQWIIGGDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVG
                     AIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIA
                     YAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQ
                     GFLKGEVRYASVMKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGAE"
     CDS             complement(3625..4491)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAILLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(4512..5336)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="BPD_transp_1 (E-value: 5.9e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(5333..6559)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGHEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(6859..7254)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="LQILFFLSSFGNEINKVQAMKDYKVDKASLSTSFCQEVYQVVREI
                     PVGKVSTYGGIAALLGMPQCSRMVGRALKQVPDDLSTPCHRVVNASGRLVPGWTEQKQL
                     LLEEGISFKQNGCVDLKKHLWNYSVSE"
     CDS             7280..8668
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGV
                     FAFSSCEKNLYDESKQPEKEIQVKDLDIPAGFQWKLTQVAAGTVAATTPTMVSFFLDEA
                     CSKEEKIADIPVDTEISSLPLSIPTYVNTLYAQYKTSTNETKKVAIPVNADRSFSLNIA
                     NDAKSKSNTTRSITRGHDIEDDIQLSKGVIFHPKDGWGTIMFEDQFPSLGDYDFNDFVV
                     NYKVQFQGIRKVDKKYTAQYIQIGLRLKAIGGIFPYSPYLRLKEIDSDEVESIEVYETK
                     NVIPAIDGVELVPNKHLIIDYSPLIKNLAKPAGSQYYNTEKNALVATSDLPEINILITL
                     KKRKEVKEILEGDEFDLYLKRNDSGTEIHMNGIEPITYQYPFNDKNLLPIYTNGDEEDD
                     NYYFSAGRLIWGLRVPGNAAHAIEKANFLEAYKGFAKWAQSSGKNEQNWYNQGNADKSL
                     LIHN"
     CDS             complement(8749..11577)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 61.6; E-value: 2.6e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.8e-19, bitscore:
                     61.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMGYTKWIAVLLCLLGMTACRQDTHRFRIGVAQCSDDSWRHKMND
                     EILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDEGVDLLIISANEAAPMTPIVEEAY
                     QKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGSTPA
                     MERHQGFMAAISNFPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRIAPG
                     AYQAAKKVGREKEMIFVGIDALPGKGNGLEMVLDSVLNATFIYPTNGDKVMQLAMNILE
                     KKPYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQVVMY
                     GGLVILLLVAGLLLVVYKSLRAKNRLNKELSEQKKQLEEQRDKLEEQRDQLEEQRDKLE
                     EQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADHTLSGDQHRML
                     MLIQRNVNILLRLVNQILDFRKYENGKMEYTPVQIDVLSSFEGWNESFLAAARKKHIHF
                     SFDNMPDTDYHTLADMEKLERIYFNLLSNAFKFTPENGKITVRLSSLTKEDTRWIRFTV
                     ANTGSMISAEHIRSIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTISVESDEKQGTVF
                     TVDLPVQTCETILAEDSLKSSISAVPLNPASPGSPASSDLNGTLAAEEEELEKGYDSSK
                     PSVLVIDDNADIRSYVRGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGI
                     ECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLID
                     SHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGLSRVQ
                     LYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCYREQF
                     GESPTDLLKRKG"
     CDS             complement(11967..13085)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKHVSILFRSKCWNVFLLLCIALPSLAQKEFKIDQVSVVNVGDGR
                     FLYRDLMTEKPLNGEHRIIDGYHSAYILASFKDGFYDGKYEEHLDNILINEGVYKDGRK
                     NGLFKIYSKFDGKLKEEKSYKEGKLNGTSKTFFTDGKIESEKNYRMGKEDGKHLSYDYD
                     GTLRMDHNYKDGKQVGKQYTFMKGTYELYETVYYNNEGLKDGEYSSIFTFGAPHVLGSY
                     KNGQKNGRWTEIAESGDTIVIETYLNGKEEGLHVSYSGETGMRTKEYYLKNDRKDGIYR
                     EYDLKNGELKYEATYQFGRLHGKARQLVVDNRFDYWETSTYVNGRQNGPFESRYVKNNK
                     LRECGEYKNGHRVGRWKLYTIDGKLEREWDEN"
ORIGIN
        1 agcagctatc taccccatca ctccttcttc gactatggct gagtacgtag acgaatgggc
       61 tgccgcagga cgtaagaaca tcttcggcga aacagtatta gtacaggaaa tgcaatctga
      121 aggtggtgct gccggtgcag ttcacggttc tcttcaggct ggtgcgttga ctactactta
      181 cactgcttcc cagggtcttc tcctgatgat ccctaacatg tacaaaattg ccggtgagtt
      241 cttgccttgc gtattccatg tatctgctcg tacattggct tctcacgcat tgtgtatctt
      301 cggtgaccac caagacgtaa tgtcagctcg tcagactggc tttgctatgt tggctgaagg
      361 ctctgtacag gaagttatgg atttggctgg tgttgctcac ttggctacca tcaaatctcg
      421 cgttccgttc atgaacttct tcgatggttt ccgtacatct cacgaaatcc aaaagattga
      481 aatgttggaa aatgatgatc ttgctccgct gatcgaccaa gaagctttgg ctgaattccg
      541 tgcccgcgca ctgaacccga tgaaaccggt agctcgtggt atggctgaaa atcctgacca
      601 tttcttccaa catcgtgaat catgcaacaa ctactatgaa gcagttcctg ctatcgtaga
      661 agaatacatg aatgaaattt ctaagatcac aggtcgtaaa tacggtttgt tcgattacta
      721 tggtgcagaa gatgcagaac gcgtaattat cgctatgggt tctgtaacag aagctgcccg
      781 cgaagctatc gactacctgg tagcaaacgg cgaaaaagtg ggtatggttg ccgtacacct
      841 gtatcgtccg ttctctgcta aacacttctt ggctgctgta cctaagactg ctaagactat
      901 cgcagttctt gaccgtacta aagaaccggg tgctaacggt gaacctcttt accttgacgt
      961 taaagactgc ttctacggtg cagaaaatgc tccggttatc gttggcggtc gctacggttt
     1021 gggttcaaaa gatactactc ctgctcaaat cctttcagta ttcgaaaact tggctatgcc
     1081 aatgccgaag aaccacttca ctatcggtat cgtagacgac gttactttca cttctcttcc
     1141 tcaaaaagaa gaaatcgctt taggcggcga aggtatgttc gaagctaaat tctacggttt
     1201 gggtgctgac ggtacagtag gtgctaacaa gaactctgta aagattatcg gtgacaacac
     1261 tgacaaacac tgccaggctt acttctctta tgactctaag aagtcgggcg gtttcacttg
     1321 ttctcacttg cgtttcggtg acaatccaat ccgttctact tatctggtaa atactccgaa
     1381 cttcgttgct tgtcacgttc aggcttacct gcacatgtac gatgtaactc gtggtttgcg
     1441 taagaacggt tctttcttgc tgaacacaat ctgggaaggt gaagaactgg ctaagaacct
     1501 gcctaacaag gttaagaaat attttgcaca gaacaacatt tctgtatact atatcaacgc
     1561 aacacaaatt gcactggaaa ttggtttggg taaccgtacc aacacaatcc ttcaatctgc
     1621 attcttccgt atcacaggcg ttattcctgt agaccaagct gttgagcaga tgaagaaatt
     1681 catcgttaag tcttacggca agaagggtga agacgttgtt aacaagaact atgctgccgt
     1741 tgaccgtggt ggtgaataca agactttggc tgttgatcct gcttgggcta accttccgga
     1801 tgacgcaaaa gctgaaaaca acgatcctgc attcatcaac gaagtagttc gtccgatcaa
     1861 tgcacaagac ggtgacttgt tgccggtatc tgcattcaag ggtatcgaag acggtacttg
     1921 gtatcaaggt actgctaaat acgaaaaacg tggtgtagct gcattcgttc ctgaatggaa
     1981 tccggaaaac tgtatccagt gtaacaagtg tgcatacgtt tgccctcacg cttctatccg
     2041 tccgttcgta ctcgacgctg aagagcagaa gggtgctaag ttcgaacaac tgaaagctgt
     2101 aggtaaagca ttcgacggta tgacattccg tatccaggtg gacgttctcg actgtctggg
     2161 ttgcggtaac tgtgctgaca tctgtccggg taatccgaag aagggtggca aagcattgac
     2221 aatgaaacac ctcgaaagcc aattggctca agctgaaaac tggacttact gtgctgaaaa
     2281 cgtgaagact aaacaacatc ttgttgatat caaggctaac gtgaagaact cacagttcgc
     2341 tactccgttg tttgagttct ccggcgcttg ctctggttgt ggtgaaactc cgtacgtgaa
     2401 attgatttct caattgttcg gtgaccgtga aatggttgct aacgctaccg gatgttcttc
     2461 tatctactct ggttctgttc cttctactcc gtatactaca aacgaaaacg gacacggtcc
     2521 tgcttgggct aactcactgt tcgaagactt ctgtgaattc ggtttgggta tggaactggc
     2581 taacgaaaag atgcgtgctc gtctcgtgaa agtgatgaac gaggctattg ctgctgattg
     2641 cactcctgct gaagtaaaag aactgttcgc tgaatggatc aacaatatgc tggatgcgga
     2701 caagactaag gaattggctg ctaagatcat tccggttgtt gaagctaaca aggataaatg
     2761 taaccactgc aaacaaatcg ctgaactgca acaatatctt gtaaaacgca gccagtggat
     2821 cattggtggt gacggtgctt cttacgatat cggttacggt ggtcttgacc atgtaatcgc
     2881 ttccggtaag gacgttaaca tcctcgttct ggatactgaa gtttactcta acacaggtgg
     2941 tcagtcttct aaagctactc cggtaggtgc tatcgctaag ttcgctgctg ctggtaagcg
     3001 cgtacgtaag aaagacctcg gtctgatggc tactacttac ggttatgtat atgttgcaca
     3061 gatcgctatg ggtgctgacc aagctcaaac tctgaaagct atccgtgaag ctgaagcata
     3121 tccgggacca tctttgatta tcgcttatgc tccatgtatc aaccacggtc tgaaagcagg
     3181 tatgggtaag agccaagaag aagaagaaaa agctgttaag tgcggttact ggcacttgtg
     3241 gcgttacaac ccggctttgg aagaagaagg caagaaccca ttccaattgg atagcaaaga
     3301 accgaactgg gaagatttcc aaggtttctt gaagggtgaa gttcgttacg cttctgtaat
     3361 gaaacaatat cctgctgaag ctgaagaact gttcaaagct gctgaagaaa acgctaaatg
     3421 gcgttacaac agctacaaac gtttggctag agaaaactgg ggtgctgaat aatagtaata
     3481 ccctataaat ataaaacggt aatcttgtag aagattaccg tttttttatt gtatgaactc
     3541 tgtctaacat aaacaatact ccctttttcc cactagagtt catgtctatt ttatatttaa
     3601 aattaaaaat aacaatgctc caatctattt attctctgac ttcggaatcc aactatccac
     3661 caactgccga tgttcatccc tccatttacg ggctatttct tcttcatcca tccgggcatc
     3721 cttcatagct gtcataaaag agctaagttc ttctgtcgtt agtttgatgt tgccaaagaa
     3781 ttcggcagca aacggatctt tctcactgaa tcctttccat gcaatagcat gtatttcttc
     3841 caagtctcca tatactttct tcggatcatc caagaatttc aagtcaaact ggtcgaacat
     3901 ccaatgcggt gtccaccccg tgatgacaat ccattctcct ttgtccatcg cttttttcaa
     3961 agaagccagc atggtggaac tacttgaagt catgagggta tacccatcaa gtccgtaagc
     4021 agcaatggcc ttatcggtcg tcttcataat tcctgctccg gcatcaattc ccactatttc
     4081 agaagagaaa cggtctttat tagcttccag ctcactaata gactggatcg taacatattg
     4141 aggaacaacc agtcctacac gggcttctcc atatacctca cccaaaaatt cgatgctgtc
     4201 tccatactga tccatataat ctttcatcgt tattggtaac caggcatcca gaaagacatc
     4261 agatttcttt cctgacatag atacaaagat gggggcaagg tcagcatttt gcagttcaac
     4321 ctcatatcca tgttcttcca ataccacctt agccaaatga ctcatggcaa taccttccag
     4381 ccaattggca taggctatct ttactttctt tttctctaaa tctgaattag tacaggaagc
     4441 cagcaaaagt atagctgaca atactattcc tactatttta tatattctca tacgtatttt
     4501 atcctttccg tttagttctt attttttcgt cctgccattc cttgtgtgat acggtctaag
     4561 atgatagcta aaataacaac tgcgatacca ccttcaaacc caagtccgat tttcatttgg
     4621 gtaatacctt tcaatacaat ttctcccaga ccaccggcag caatcatggc agcaatgaca
     4681 accatagaaa gcgacatcat tattgtctga ttgacacctg tcaggatggt tggcaacgcc
     4741 aaaggaagct gcactttata caataactgc caacgggtag ccccgaacga acgggaagct
     4801 tccactacat ttttaggaac ttgccgaatt cccaatccag taaggcggac cacaggaggc
     4861 atagcaaaga taatggtggc aaacactccc ggcactgctc ccaatccgaa aaacaaaacg
     4921 gcaggaatca gataaacaaa agcaggcatc gtctgcatca agtcgagaac aggacgaagt
     4981 attttctctg cacgcggact gtttgccgtc cacactccta aaggtacacc aacaatcaga
     5041 gccagacagg tagatgaaaa aacgagagcc agggtttgca tagtagcctc ccaaaatccc
     5101 attccataaa tcagtaataa tcctaatgcg gtgaaaattg ccgtaccacg tcctgccttc
     5161 atccatgcga gtgcagcaag cactagaatg gttatataaa aaggtattcc aaaaagtacg
     5221 tgttggaatc ctataataaa actaccgatg cctgcattca cggcatcaaa gaaagtggaa
     5281 aaatgtacca tcatccaatt gatggccatc tctatatatt gtcctatatt tatcataaat
     5341 ctattgcgtt ttgaattatt tcgtttattt cttctttatc tttccccgtc acttcgatga
     5401 ttaaggagga aagcgggatt gttcctaaaa actcatgcgt ctcatcaatc acccataccg
     5461 gcgaattgct ctttgtcatt aaaggaagta tatcctccaa cactgtatcc tccaatacag
     5521 aatgtacttc tgtacgcaca atcgtttcaa tggatttttc ctgtctgcta cgtaacttaa
     5581 gcaggtcgtt cagacgtact tctccgacca gtttatcatc ggcgtctatg acaggtaata
     5641 cggtgatatt cttcgcacgc atcttacgaa tcaatacttc aggtccctct ttcttcagac
     5701 gggccaccag tggtttgtca atcattaaag aagaagcggt gataatttta ctcctgtcca
     5761 cgttttcaac aaaacgggct acataatcgt tagccggttc ggtcagtatt tcttctgaag
     5821 tacctacctg caccacctct ccgtctttca taatggcaat acggtcgccc agtttaatcg
     5881 cttcactcaa gtcatgggta ataaagacaa ttgttttttt catcttcgac tgcaaagcca
     5941 gcagttcatc ctgcatttgc acacgaatca gaggatcgag cgcagagaaa gcctcatcca
     6001 ttaaaagcac ttcgggatta ttagccagag cacgggccag tccgacacgc tgttgcattc
     6061 caccggaaag ctcgcccacc atctgatttt catatccttt caatccgaca agcttcatac
     6121 tttccatcgc tttcttctca cgttcctctt tcttcactcc ctgaagttcg agaccgaacg
     6181 cgatattgct caatacggaa cggtgaggta acagaccgaa attctggaaa accatcgcca
     6241 actctttccg gcgaacttgc aataactctt tttcggatat tttagatata tctactccgt
     6301 ttacaagcac ttgtccggca gtaggacgta tcagacgatt gatacaacgc agtaatgtcg
     6361 attttccact tcccgagagt cccattatca caaaaaactc tccttcatta attgaaagat
     6421 tggcatcttt cactcctacc gtacaaccgg tatctttcag aatttcctct ttactcttat
     6481 cttttttcaa catcttgagt gctttctgct tctcgtgacc aaagataagg tacaaatcct
     6541 ttatttctat tttactcata taatatattg gtttagatta taatagttgt tttgttttca
     6601 actgctgcgt tcctcattct cacttacgat aaacaagttg aatgttcgca tggttcagtc
     6661 atgtcacatg acaacatgat gatccgacgt tttttaaaat ggttttaaaa gacagactga
     6721 gtagtttaaa aggaatagaa tttgataaga ttatcctctc aatgaacagt agaaaacagt
     6781 attttcataa ataaataaca gtctgttctt gcatattgtt ggcacaaagg taagggaaat
     6841 agattaaata tgcaaatttc attcagatac ggagtaattc caaagatgct ttttcaagtc
     6901 tacgcatcca ttttgcttga aagagatccc ttcttccaac aagagttgtt tctgctctgt
     6961 ccaccccgga acaaggcgtc ccgatgcatt gacaacccgg tgacaaggcg tagataaatc
     7021 atccggaacc tgtttcaagg cacgccccac catacgggaa cattgaggca ttcccaataa
     7081 tgcggcaatt cccccatagg tagaaacttt acctaccgga atttcccgaa caacctgata
     7141 cacctcctga caaaaggatg tggaaaggct tgccttatct actttataat ctttcatcgc
     7201 ctggacttta tttatttcat tcccaaagct agataaaaag aagagaattt gcaaataaca
     7261 aaagcatttc aaataaaata tgcaacttta tttgctttat ttacaaataa tcccgacctt
     7321 tgtacccatt aaaagcaacc ctattattaa caaaacaagc actgctgtta tgaaaaagaa
     7381 gacaattcta ttcgcttctt gtttattggg agtattcgct ttcagctcct gtgagaagaa
     7441 cctttatgat gaaagcaagc aacctgaaaa agaaattcaa gtaaaagacc tggatatacc
     7501 cgcaggcttt caatggaaat taactcaagt agccgcagga acagtagctg ctactacccc
     7561 cactatggtt tccttctttt tggatgaagc atgtagtaaa gaagagaaaa tagccgacat
     7621 tcctgtagat acagaaattt caagtctccc tttgagcatc ccaacctacg taaatacatt
     7681 gtatgcccag tacaaaacca gcaccaatga aaccaaaaaa gtagccatac ctgtaaatgc
     7741 agatagaagt ttctcactga acattgctaa tgatgccaaa tccaaatcta acaccacccg
     7801 gtcaatcact cgtgggcatg atatagaaga tgacatccaa ttgtcaaaag gagtcatttt
     7861 tcatcccaaa gatggttggg gaacaatcat gtttgaagac caatttccat cattaggaga
     7921 ttatgacttt aatgattttg tagtcaatta taaggtgcag ttccaaggta ttagaaaggt
     7981 tgacaaaaaa tacactgcgc agtatataca aatagggtta cgtctaaaag ctatcggagg
     8041 aatattccct tattcccctt atttaagact gaaagaaata gattctgacg aagtggaaag
     8101 tatagaagtt tatgaaacta aaaacgtgat tcctgcgatc gacggagtag aacttgtccc
     8161 caataaacat cttatcattg attacagccc tttaattaag aatctggcta aacctgcagg
     8221 cagccaatat tataatacag aaaagaatgc tttggtagca acaagtgatt taccggagat
     8281 caatattctg atcaccctaa agaagagaaa agaagtaaag gaaatattag aaggcgatga
     8341 attcgacttg tatttaaaac gtaatgatag cggaacagaa atccatatga atggtattga
     8401 accgatcact taccaatatc cattcaatga taaaaatctg ctaccgatat atacaaacgg
     8461 ggacgaagaa gatgataatt attattttag tgcaggacgc ctgatttggg gattaagagt
     8521 accaggcaac gcagcgcatg ctattgaaaa agctaatttc ttggaagcct ataaaggatt
     8581 tgcaaaatgg gcgcaaagta gtggcaaaaa cgaacaaaac tggtataatc aaggaaacgc
     8641 agataaaagt ttattgattc ataactaaca catatcaata aatcccggca aacattgaaa
     8701 attcaagtta ccgggattta ttgtattcta acgtgaatag ttttgattct atcctttcct
     8761 cttcagcaaa tctgtcggac tttctccaaa ctgctctcta taacatttgg taaaataaga
     8821 aggagagctg aaaccgactt cataaccaat ctctgccact gtcatatccg acgaagcaag
     8881 cagggaagca gctttcttta aacgagcgat acgaagcaat tcattcggag aataattagt
     8941 caaggatttt attttgcgat agagctgcac acgacttaat cccatatcct tacccaaatc
     9001 ttctacattc aaatttgagt ctcccatctt tgcttcaatc aaagccttga atttttccac
     9061 aaaatcttta tccatatcac agacatcctc tttcgccaac gtttgtccgt caccaaagaa
     9121 ctgtttcagg cggcgatgtg aatctatcag attacgaacg cgtgccaaca gcaattgcga
     9181 actgaagggc ttggagatat aagaatccgc acctccgtca tatccctgaa tccgttgttc
     9241 atccaaagaa caggctgtca ataagatgac agggatatgg caggtttgca gttcgctttt
     9301 cagccgacga cagcactcta ttccatcaat accaggcatc atcacatcag agattatcaa
     9361 gtccggaaca tatttcattg ctttgcggat gccctccgaa ccgtctgctg cttcaattac
     9421 agtataatcg gtatggagta atccgcgtac atacgaacgg atatctgcat tatcatcaat
     9481 taccaaaacg gaaggtttgg aagaatcata gcctttttcc agttcctctt cttcggcagc
     9541 taaagttcca ttcaggtcgg aagaggcggg agatccggga gaagcaggat ttaaaggaac
     9601 tgcagagatt gatgacttta gagaatcttc ggccagaata gtttcacaag tctgtaccgg
     9661 taaatcaacg gtaaaaacag tgccctgctt ttcatcactt tccacagaaa ttgtaccttt
     9721 atgcaattca acgaaagctt tgaccaatgc aagcccgatt cccgaaccgg catggtgcat
     9781 gtctatttta taaaaacgat cgaaaatgct ccgaatatgt tcggcggaaa tcattgaacc
     9841 ggtattggca acagtaaaac gaatccagcg agtatcctct ttcgttaagg aagataaacg
     9901 aaccgttatc tttccatttt ccggtgtgaa cttgaacgcg ttggaaagca gattaaaata
     9961 aatacgttcc aacttttcca tatccgccaa tgtatggtaa tccgtatccg gcatattatc
    10021 aaaagagaaa tgaatgtgtt tcttccgggc cgctgcaagg aatgattcgt tccagccctc
    10081 aaaagaggaa agaacatcta tctgaacagg tgtatattcc atcttaccgt tctcgtattt
    10141 acggaaatcc agaatctgat tgacaagacg taagaggata ttcacgtttc gttgaatcag
    10201 catcaacatt cgatgctgat ctccacttag tgtatgatcg gccaataaat gttctaccgg
    10261 atcggcaacc aatgtaagcg gagtacggaa atcgtgagat atatttgtga agaacaccag
    10321 tttggcatgc gttgcctctt ccagttgatg agaaagctgg atgagctgat cccgttgctc
    10381 ttccagtttg tcccgctgtt cttctaattg gtcacgttgt tcctctaact tgtcccgttg
    10441 ctcttccagc tgtttcttct gctcggaaag ttccttattc agacgatttt tagcacggag
    10501 agatttatag actaccaata ataagcctgc caccaataga agaataacca aaccgccata
    10561 catcaccacc tgctgtgtag caacccgaga cagatatccg ccgatacgtc cgttcaatgt
    10621 ttcaatcttc tgatccagtt ccgagatgtg agttgtctga agttgcatga catgcgcatt
    10681 cgtacggtcg accaccgcag tgttcatgac cgtttcccgg ggataaggct ttttctcaag
    10741 gatattcatt gccagttgca tcactttgtc gccattggtc ggataaataa aagtagcatt
    10801 caacacactg tcgagcacca tttccaatcc gttgcctttg ccggggagag catcgatacc
    10861 gacaaaaatc atttccttct cccgtcccac tttctttgca gcctgataag ctcccggagc
    10921 gatacggtca ttatgcgcat acacggcgtc tatcttcgga tgccgacgga gcatactatc
    10981 catttccact tccgccggtt cacgctccca cgcagcatcc gctttatcaa tcagtttgat
    11041 atccggaaag ttactgatag cagccataaa tccttgatgg cgttccatgg caggagttga
    11101 gccacccagt ccagtaagtt ccaccacatt cccttttcct ttcaggcttg acgcaatata
    11161 attgcctacc gcacgtccta tttcataatt gtcggcaccg atataggcag tatatttatc
    11221 agaaagaatc ttccggtcta ccaggatgac aggtattccc ttttgatagg cttcctctac
    11281 aatcggagtc atgggggccg cttcgttggc agaaataatc aataagtcaa ccccttcatc
    11341 tataaaataa tgaacgtcct ccgcctgttt gcgattatca tccgcagccg accggatttc
    11401 aaccgatacc ccatcgtaga acattgcttc gcgaagaatt tcatcattca tcttatgccg
    11461 ccaggagtca tcactacatt gcgccacccc gatacggaag cggtgtgtgt cctgccgaca
    11521 agccgtcatg ccaagaagac agagcaagac tgctatccac tttgtatatc ccatcattct
    11581 catttttttc gtatttcttt ctatgaccca aatggacgat tgagaacaaa aataagaaat
    11641 aaaactgtga gtatgctatc tatcacccaa ttattctcat cattaccctc caaagaaatg
    11701 caaaacagtt cccaatattc aaccggaaac tattaacaaa agtataaagc gtaagacaaa
    11761 cactcaataa atgttataaa acatctcttt ttatttggat tatttgcaga tttaacagaa
    11821 gtccgtatct ttgcaatgtg tttttcatag tattagattt aaggttaaca aaggttggag
    11881 caaggcgttg ctcctttttt tatgtctgta cggctacgcc ttgcactctg tataacacct
    11941 acaacctata tgacagttga taagacctag ttttcatccc attccctttc cagtttgcca
    12001 tcaatggtat aaagtttcca acgtcctacc cggtgaccgt tcttatattc tccacattcg
    12061 cggagcttgt tattcttcac ataacgagat tcaaaaggac cgttttgccg tccgttgacg
    12121 tatgtagaag tttcccaata atcaaagcga ttgtccacca ctaactggcg tgcttttccg
    12181 tgcagtctgc caaactgata ggttgcctcg tacttcaatt cgccattttt caagtcatat
    12241 tcacgataga ttccgtcctt gcggtcattt ttcagataat attctttggt acgcatccct
    12301 gtctcaccac tgtatgaaac gtgcaggcct tcttcttttc cattcagata agtttcaatt
    12361 acaatggtat cgccactctc tgcaatctct gtccaacgac cgttcttctg cccattcttg
    12421 taactaccca atacatgagg agctccaaaa gtaaagatgg acgaatattc tccatccttc
    12481 aacccttcgt tattataata aaccgtttcg tatagttcat aagtaccctt catgaaagta
    12541 tattgtttcc ctacttgttt accatcctta taattatggt ccatccgcag agttccgtca
    12601 taatcatacg acaaatgttt tccatcctcc ttgcccatcc ggtagttttt ctcactttct
    12661 atttttccgt cagtaaagaa cgttttgctc gtaccgttca actttccttc cttataagac
    12721 ttttcttctt tcagtttacc gtcaaactta gaatagattt taaataagcc attcttccgt
    12781 ccatctttgt agacgccttc atttatcaga atgttatcca aatgctcttc atatttgcca
    12841 tcataaaaac catctttaaa agaggccagt atatacgcag agtgataacc gtcaatgata
    12901 cgatgttcgc cgttgagcgg tttttccgtc atcaagtctc ggtacaagaa tcttccgtcg
    12961 cctacattaa cgacagatac ctgatcgatt ttaaactctt tttgtgctaa tgagggaagg
    13021 gctatgcata gaagcaaaaa tacattccag catttcgagc ggaataaaat agaaacgtgt
    13081 ttcataatgt gacattctct ttttagttat tatcttgtga atcgtgcaaa gatatacaat
    13141 tagctaaaaa tccaacaata aaaagagaag aaaagaggtg atatccgaaa agatttgaat
    13201 taaaaaaatc ctccttacta caacataccg tagtaagaag gattttcact tttggattct
    13261 tttcgtccct acatttacat caatagagaa attacatcag cctgtctttc aaaacctgcg
    13321 gaagttcggg cattgcaccg ctttgcgtgc agacataagc agaaacttca acggcaagtt
    13381 tgtgagcttc tggtaccggt tttccattga gaatggaagc acagaaagca gccgtaaagg
    13441 aatcacctgc ccccaccgta tcggcaaccg ga
//
