LOCUS       c00016_gnlPro..        16267 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBPAGIDJ_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:58:15
            Original ID  :: gnl|Prokka|PBPAGIDJ_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16267
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16267
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3424:6267]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3425..6267
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16267
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16267
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             267..554
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MCIPATGIDCPHFQNAEKIHVAWGISHLLDNVPYKDGTNIKQQLI
                     GHFGKTLYYRFYREERFLSPADQNYIRQLFHRKGITEEPVFDSYTDEYNW"
     CDS             909..1577
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MEEVIRKYVDECWGFVQEHREYLMYVPSYEEHIEPEMQDTFDNII
                     PQGKSVKIYVTQPEHTNYMVDIITEKDHVWKAIDNQISDEDISKLESKLNVILPLSYKI
                     YLKYKHFYEIFWDLDVRLYPKPIHSWNKILIENNEELQEEILNKGYFAIGRYSDYGVIA
                     LKLTDDENKEGEILLFDYETPETEVLAPNFIEFLNQILQNPKPVLQELKGWEKKMYKME
                     "
     CDS             1689..2306
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MGYLPLPYNKDRNKVFYKEMDNGLIVCVGIESSSLYQDRRKTVSF
                     YTALSYTWAMYSPILLPQDCYLRIGEILGKNDLWFQTTTKEEKDFMCQSIQQAARICEK
                     QSKIILHYILKENQYVEYKEYICRLNCIIDFVKKQGITSNADISIIYEVIKPVLKRIGV
                     PLSKHTTKLYAVDAMNCIHCSSDINKQQRKIIASEIISVTNG"
     CDS             2506..2850
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="LPYQYKRFLLWSNGGEGKLGDNYIYIWAIEDIVAYNNDYGIHKYL
                     QKEYLAFGMDGDIGYIFHLPNNSIYRVDLGDLDIASIKYIAPSFDDFLGKAIYLNFDKP
                     QNIVDNSSTI"
     CDS             3425..3652
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="Fer4_7 (E-value: 3.6e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6e-10, bitscore: 30.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.2e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.7e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCATVCPDGCISVYKVKVE"
     CDS             3664..4746
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="PFOR_II (E-value: 5.7e-28, bitscore: 88.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.5e-50, bitscore: 162.3,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKKVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYKLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTEAEVIEQCPWAATGKAKDRKPNIITSLEL
                     KPEAMEINNLRFQAKYREIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALKEKIIK"
     CDS             4940..5704
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-26, bitscore:
                     83.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTVGISPVGCAVFAYNYLDIDWQEAAHGRAPAVATAVKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKANKWMEEHMFPFYPLGDLKDKE"
     CDS             5725..6267
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_8"
                     /sec_met_domain="POR (E-value: 2.3e-36, bitscore: 117.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDAAIILNQPSLEKFESKVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLKLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIREV"
     CDS             6377..8440
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="LPPIMRRILLLYIIFSVIGLTTVHAQFDNGRQRVDENGYDQYGNQ
                     VDPAMIPDRLDSANVEVQGLPPKLYMWRINNQLGDRTIIPADTAYHHFQNSNLTEGLTG
                     HYNYLANMGSPRMSRIFFERRDPEPTIFMEPFSSFFIRPTEFNFTNSNVPYTNLTYHKA
                     GNKINGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTAYFNAAIFGSYIGDRYQ
                     MQAIYSNNYLKTNENGGIEDDRYITAPEEMAQGQREYESTNIPTVLSATTNRNHDFYVF
                     LTQRYNLGFSRDIPQAENDTTPAKQEFVPVTSFIHTIQVERARHSFNSDDDMREKNYYQ
                     NTYLEPDNPIARDSTTYMGIKNTIGIALLEGFNKYAKAGLTAFASYKISKYTLMNMEGN
                     PLPDKYNENEIFVGGELSKREGNVLHYHAIGEVGLAGKAIGQFNVKGDIDLNFPLWKDT
                     VSLIARGEVSNKLAPFYMRHYHSKHFMWDNDMDKEFRTRIEGELSIARWRTRLKAGVEN
                     IKNYTYFNQQAVPEQKSGSIQVLSASLNQDFKLGIFHLDNEVTWQKSSDQTVLPLPDLS
                     LYHNFYMQFKLAKKVLSVQLGADVRYFSKYNAPAYMPAIQNFYLQPENDQVEIGGYPIV
                     NVYANLHLKRTRFYVMMYHVNQGMSSPNYFLAPHYPINPRVLKFGLSWNFYD"
     CDS             8458..9297
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MVTRPKLRLARYLVPVIIVLAIIFSIRQCGNQEKPSGHPRDYAAI
                     AKEGILRVATEYNSISFYVDGDTVSGFHYELIQAFAHDKGLKTEITPLMSFEERLEGLS
                     EGRYDVIACGILATSELKDSLLLTSPITLNKQVLVQRKENGENDSLHIRSQLDLAGRTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIEKYGSEQLISMVAHGDIDYAVCDESIARAAA
                     DSIPQIDINTAISFTQFYSWAVSKQSPALLDSLNTWLDKFQKEKEYQKIYKKYYDKE"
     CDS             9810..10796
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_11"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.1e-26, bitscore:
                     85.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 2.8e-08,
                     bitscore: 25.3, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIKKWYDDAQELIDDPEVNAIYIATPPSSHATYAIMSMKAGKPAYIEKPMAVT
                     YEECTRINRISNETGVPCFVAYYRRYLPYFQKVKELVENGTIGNVINVQIRFAQPPRDL
                     DYNRDNLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDNGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTEKGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             10952..11422
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="MTKEALMRKAIELSKENVENGGGPFGAVIATKDGEIVATGVNRVT
                     ASCDPTAHAEVSAIRAAAAKLGTFDLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNK
                     TDAKNIGFDDSFIYDELQLKPEDRKLPSEILLHNEALTAFKAWVAKEDRVEY"
     CDS             11489..12271
                     /locus_tag="ctg16_13"
                     /transl_table=11
                     /translation="MASVCLFSCQQQEELQDPSNGVIDFSTSIDQSINNALTRNSSSLT
                     LPLKSNFAAGDVISMSVAEQDYHPFAIGMDSQTWNEAGTDSETVTFYAHYPELTDEAAT
                     TRSLSSRYREIKGGLEYLFGTAQANKGSKSVALAFKRMTTPVVLLDENNQPYEGRAIVK
                     LFLKNKGVQDLFSGKIEADPNAKPEYIDIRKVSEGILTNLIPQLIKAGEKIGTVILEDG
                     KEEPIIAEEDITIEAGTPVAVKMYARRGIIDERTPLFR"
     CDS             complement(12391..13986)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKSNRILAICILLISVGFLNAQTTIYDANRWMGSDLNGTARFVGM
                     GGAMGALGGDITTIGTNPAGIGIYRSNDVMVSFGFDNTGVKANGASLDKFHGSFDNAGF
                     VFSTKIGNTTALRFANFGFNYRKMKSFNRSMLVSGVFNTSQTVQMANMVNFDSYRDFDP
                     FTEAALRSDDAFQNPELPWLGIMGYNAHLVNPVYGKVDPENPDAVPPFEGYEPYFQAGD
                     AVSQSYRSKESGGIHSFDLNGALNFYDRFYVGATLGLYSVNYDRTSEYNEDFTDKDGNG
                     HGGYTLGNDFWVDGSGVDFKLGFILRPFESSSFRIGAAVHTPTFFSLKERNTAYINFDL
                     NETTRGITKPYDARGNDTEGEYEYKLITPWKFNASMGYTIGSSVALGVEYEYSDRTSAK
                     MKDPDGYELGQTEDIKAMMKAVHTLRVGAEFKLAPEFAFRLGYNHITAPLKSDAFKYLP
                     VNSMRTDTEFSNPGATNNYTLGCGYRGESFYVDMAYMYNTYKETFYAFDSLDLPGTKVT
                     NNNHKVVLTLGMRF"
     CDS             complement(14012..15346)
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MKKIVYFLLFALCLPIGIFAQSVDDDLYFVPSKDKQEKKETPVKK
                     EPKKQVTTNIYTSPGTTVVVQDRKGRTRDVDEYNRRYDARENEFVMDNDTLYIKEKSNP
                     DLDGEWVTGEFNGTTDDYEYAERIIRFRNPRFAISISSPLYWDVVYGPNSWDWNVYTDG
                     MYAYAFPTFSNPLWWDWRYGSYGWGWNYGWGWNRPYYSWGYYPGYWGGGYWGGWYGGGY
                     WGHHHHWHGGPSWGWGGGGRPYYAGRSVINGNNRSYYSGSRNYNSTSYRRGVGSSTTRP
                     ANSSVGQSVRRSGSTGTNSRVVGTRDYTRSGSNSSVRSGSSYSRRNTETYTRPSSTRTS
                     GTSTRNSGSSYNRSNSSTRSSGTNSSRSSSSYSRGSSTSPSRSYTPDRSSSRSSNSGSY
                     SRSSGSSYSSGSSGSYSRSSGSSGSSSRSSGGGGSSRSSGGSYRR"
ORIGIN
        1 tcaaccataa agatacaaaa acttgcagat atatcaaagc aatttatata ttaatatgtt
       61 gattattagg cgtaaaagca cattctaagg ggcgactatg taatatacaa tataaaatga
      121 acgacaataa attaaaaaac aaaacagtcc ctttcaacta cgcccgctgc tacaacgagc
      181 aatgtccgaa agcttgtaac tgcctgcgtc gggtggctgc acttctcact accgctgaca
      241 cgtcctacat cagcatcgta aacccaatgt gtattccggc caccggcatt gactgtcccc
      301 acttccaaaa cgcagaaaag atacatgtgg catggggtat cagccacctg ctggacaacg
      361 taccttataa ggacggaaca aatatcaagc aacaactgat cggacatttc ggaaaaacgc
      421 tttactatcg cttttatcgc gaagaacgct tcctaagccc cgcagatcaa aactatatcc
      481 gccaactttt tcaccggaaa ggtatcaccg aagaaccggt ctttgacagt tacacggatg
      541 agtataattg gtaaagccgc gttctaacca gtttccagcc tgctgaaact ttttgtttca
      601 agcgctagaa actaaaagtt tcaaagggtg aaacgattcg tttcacaccg agaaacaaac
      661 tgtttcacta cgggaaacca ttcgtttcaa ggtatgaaac aaaaaatgga actagttaat
      721 gaaagcagaa gaagtatcag tgaaggatat atcgtctaaa agttatatgt aatacaagtg
      781 ttattggtga attttcagaa tgtatgtgaa agatcagaat aaagagttga agtgtacagc
      841 gtaaaattct ccaatattgt aatcaaatag acaagaacgg agtgaaaaaa tatttagaaa
      901 aaataaatat ggaagaagta ataagaaaat atgtagatga atgttggggc tttgtgcaag
      961 aacacagaga atatcttatg tatgtccctt cttatgaaga acacatagag cctgaaatgc
     1021 aggacacatt tgataatatt ataccacaag ggaaatcggt taagatatat gtcactcaac
     1081 cggaacatac taattatatg gtggacatta ttacggaaaa agaccatgta tggaaagcga
     1141 tagataatca aatttcagac gaggatattt ccaaattaga aagtaaatta aatgttattc
     1201 ttccgctttc atataagatc tacttgaaat acaaacactt ttatgaaata ttttgggatt
     1261 tagatgttcg tctatatcca aagcccattc attcatggaa taaaatctta attgaaaata
     1321 atgaggaact gcaagaagaa attcttaaca aagggtattt tgcaataggt cgatattctg
     1381 attatggcgt gatagctctt aaattgacag atgatgagaa taaagaaggt gaaatccttc
     1441 tctttgatta cgaaacgcct gaaacagaag tattagcacc caactttata gaatttctta
     1501 atcagatatt acaaaatcct aaacctgttc ttcaagaatt aaaaggttgg gagaaaaaaa
     1561 tgtataaaat ggaatgatgc tactaacaag cacctgtacc acataaacgg cagcaagccg
     1621 caaaccatta ccgatagtgc aataataaaa tgaaaaagaa tgattttata aataatcaac
     1681 tgctatcaat gggctatttg ccattgccat acaataaaga ccgcaataaa gtcttttata
     1741 aagaaatgga taatggctta atagtctgtg taggtattga gtcttcttct ttgtatcaag
     1801 acagaagaaa aactgtttca ttttatacag cattgtcata tacatgggcg atgtattcac
     1861 ctatattatt gccacaggat tgttacttac gaataggtga aatattgggt aagaatgatt
     1921 tgtggtttca aactaccaca aaagaagaaa aagattttat gtgccaatcg atacagcaag
     1981 cggcaagaat ctgcgaaaag caaagtaaaa tcatattgca ctatatctta aaagaaaatc
     2041 aatatgtgga gtataaagaa tatatatgca gattgaactg cataatagat tttgttaaaa
     2101 agcagggaat caccagtaat gcagatataa gtatcattta tgaagtgatt aaaccagtat
     2161 taaaaagaat aggtgtaccg ctttccaagc atactacaaa actatatgca gtggatgcca
     2221 tgaattgcat ccactgctct tcggacataa ataagcaaca aagaaaaata atagcaagcg
     2281 aaataatatc agtaacaaac gggtaaattg tcctaaaaga aatgatccgt ctgagattaa
     2341 catttatcaa aataaaaaaa taaacgagga aacagcagtt agctgaaaca cattaacagt
     2401 agtacaacaa aatcaatatg gaagtaatag aaagtaaatg gtataataaa gaatggtgca
     2461 aatacagcgt ctattgaaga cgtagaaaaa cttctaaata caaccttgcc ctatcagtac
     2521 aaaagatttc tgttatggag caatggtggc gagggtaaat taggagataa ctacatctat
     2581 atatgggcta ttgaagatat tgttgcttac aataatgact atggaataca caaatatctt
     2641 caaaaagagt atttagcatt tggcatggat ggtgatattg gatatatttt ccacctgcca
     2701 aacaatagta tatatagggt agatttagga gatttagata tagcttctat taagtatata
     2761 gcaccctctt ttgacgactt tttaggcaag gctatttatc ttaatttcga taagccacag
     2821 aatattgttg acaatagttc aaccatataa agtgattaga catggatata aataatgaat
     2881 aaactacaac tccaaaaaca ataataactc ctgattcata tcgttttttg attaataaag
     2941 ttacggatat gtcaagaaaa aggcaaattc cacctctact atacaatatg caataaactc
     3001 aaaacgttgc aaatttccgt cctcatttgc cctgtttaca taaataaaaa ctatctttgc
     3061 gtttcagaat cccgaaagac gaaaagaaat ggagcaaata gacaacctaa aagagcttat
     3121 caatcagggg gatgtggaca cagcgattaa gcaattggac cagcttctcc aggacagttc
     3181 tgtcgaaaaa gagaaagata ctctttacta tttacgggga aatgcctacc gaaagaaagg
     3241 agattggaag cgggcactgg acaactacca gtatgccatc gagctcaatc cggacagtcc
     3301 tgccgttcag gccaggaaga tggtaataga tatcctcaac ttctaccaca aggatatgtt
     3361 caatcaataa aagagatgta taatcaataa ccgtactcaa agataacgta ataaaataaa
     3421 gattatggca aaaatcaaag gagcaatcgt agtcgacacg gagcgttgca aaggatgcaa
     3481 cctgtgtgta gtggcgtgtc cgctcgatgt aatcgccctc aataaagagg taaacatgaa
     3541 aggctataac tatgcctggc aagtgaagga agatacctgt aacggatgca gctcgtgtgc
     3601 aacggtttgt ccggacggat gtatttcagt gtataaagta aaagtagaat aaaagaaaag
     3661 aatatggcag aagaagttgt attaatgaaa ggaaacgaag ccatcgccca cgcagctatc
     3721 cgttgcggtg ccgacggata cttcggttat cctattactc cccaatcgga agtgttggaa
     3781 acgcttgccg aactgaaacc gtgggaaaca accggcatgg tagtactcca ggcggaaagt
     3841 gaagtggcag ctatcaatat ggtatatgga ggtgcaggta gcggaaagaa ggtaatgacc
     3901 tcatcttcaa gtccgggtgt gagcttgaaa caagaaggaa tctcttattt ggccggtgcc
     3961 gaacttcctt gtctgattgt gaatgtaatg cgtggcggtc ccggattggg aactatccaa
     4021 cctagccagg ctgactactt ccagacagtg aaaggtggtg gtcatggaga ctacaaactg
     4081 attgccctcg ctccggcatc cgtacaggaa atggcggatt tcgtagcatt aggattcgaa
     4141 ctggccttca aataccgtaa tccggctatt atccttgccg acggtgtgat cggtcagatg
     4201 atggaaaagg ttgttcttcc tgcacaaaag ccacgccgca cggaagcaga agtaattgaa
     4261 caatgtccat gggctgctac cggaaaagca aaagaccgca aacctaatat tatcacttcc
     4321 cttgaattga aaccggaagc aatggaaatc aacaacctcc gttttcaagc taaatatcgt
     4381 gaaattgaag aaaatgaagt acgcttcgaa gagatcaact gcgaagatgc agagtatttg
     4441 attatcgctt tcggttcaat ggcacgtatt ggccagaaag caatggaact agcccgtgaa
     4501 aaaggaatta aagtaggtat ccttcgcccg attacactgt ggccgttccc aaccaaagcg
     4561 attgctgcat acgctgataa agtaaaaggt atgctcgtta cggaactaaa tgccggacag
     4621 atgattgaag atgtccgtct cgctgttaac ggtaaagtaa aggtagaaca tttcggacgt
     4681 ctaggtggca tcgttcccga tccggatgaa attgtaactg ccttgaaaga aaaaataatc
     4741 aaataacgaa acaatgaatc ccgataaaat aagaaacgta ctgaacatcc tatttatgat
     4801 attggctgtt gcagccatca tcacctactt tgtagcaaaa gatgatttca aaatgtttat
     4861 ctacgtatgc ggcgcggcaa tctttgtcaa gctgatggag ttttttatac ggttcaccaa
     4921 cagataagga gatgaagtta tgactaaaga agaaataatc aaacccgaga atctggttta
     4981 caaaaaaccg actctgatga acgataacgc catgcactac tgcccgggtt gcagtcacgg
     5041 tgtggtacac aaactcattg ccgaagtcat tgaggaaatg ggtatggaag ataaaactgt
     5101 gggaatctct ccggtgggat gtgcagtgtt tgcctacaac tatctcgata ttgactggca
     5161 agaagcagca cacggacgtg ctcctgctgt ggcgactgct gtgaaacgcc tgtggccgga
     5221 ccgtcttgtt ttcacttatc agggcgacgg tgacttggct tgtatcggta cagccgaaac
     5281 aatccacgct ttgaaccgtg gtgagaatat cacgattatc tttatcaata atgcgatcta
     5341 cggtatgaca ggcggccaga tggctccgac tacactagta ggcatgaaga gttcgacttg
     5401 tccttacgga cgtgacgttg aacttcacgg ctatccattg aagattactg aaatcgcagc
     5461 ccaactggaa ggaactgctt acgtaacccg tcagtccgta caatccgtac cggctatccg
     5521 caaggcaaag aaagcaatcc gcaaggcttt tgagaattcc atgaacggta aaggttccaa
     5581 cctggtagaa atcgtttcca cttgtagttc aggctggaag atgactccgg agaaggcgaa
     5641 caaatggatg gaagaacaca tgttcccatt ctatccgctg ggtgatttaa aagataaaga
     5701 ataacgctaa aagtcaacag aacaatgaaa gaagaaataa ttatagcagg attcggtgga
     5761 caaggcgtat tgtctatggg taagattctg gcatattccg gtttgatgga aggcaaagaa
     5821 gtgacctgga tgcccgctta tggtcccgaa caacgaggtg gaacagccaa cgttacagtt
     5881 attgtaagcg atgacaaaat ttcctcaccg attcttagta aatacgacgc tgccatcatt
     5941 ctgaatcagc cttcactcga aaagtttgaa agcaaagtga aacccggcgg tatcctgatt
     6001 tatgacggtt acggaattat caaccctcct acccgtaagg atattaaggt atatcgtatc
     6061 gacgcaatgg atgcagccaa cgagatgaac aatgccaaag cattcaacat gatcgtactt
     6121 ggcggattat tgaagcttcg ccccatcgta acgttggaga atgttatcaa aggacttaag
     6181 aaaaccctgc cggaacgcca ccatcacctg attcctatga acgaggaagc tatcaaaaaa
     6241 ggtatggagt taatccgtga ggtttaatta acagataatg tacaatggat aattgataat
     6301 tattagctac gtatagtacg tatgcaacat aattttcaat tatccattat cattaaatca
     6361 attaaagtaa gtatctttgc ctccaattat gagacgaatc ttactattat atataatctt
     6421 ttccgttata ggtttgacaa ctgtccatgc acagttcgat aatggtcgcc agagagtgga
     6481 cgaaaacgga tacgaccaat acggtaacca ggtggaccct gccatgattc cggacagact
     6541 ggatagtgca aatgtagaag tacaggggtt acctccgaaa ttatatatgt ggcgtattaa
     6601 taatcagttg ggcgaccgga ctatcatccc ggcggatact gcttatcacc acttccagaa
     6661 ttcaaatctt accgaaggac ttaccggaca ttataattat ctggccaata tgggttctcc
     6721 ccgtatgtca cgcatcttct ttgaacgtcg tgatccggaa cctactatct ttatggagcc
     6781 tttctccagt ttctttattc gtcctacgga gttcaatttc accaatagta acgtacctta
     6841 taccaatctg acgtatcata aagccggtaa taaaataaac ggagaagaac gctttaagtc
     6901 ttatttctct gtcaatgtaa acaagaagct ggctttcggt tttaacatag attacttgta
     6961 cggacgagga tattataata accagaatac ggcttatttc aatgcggcaa ttttcggtag
     7021 ttatattggc gaccgctatc agatgcaggc aatatacagc aacaattacc tcaagacaaa
     7081 tgaaaacgga ggtattgagg acgaccgata catcactgcg cctgaagaga tggcacaagg
     7141 gcaaagggaa tatgaatcaa ccaatatccc gaccgtacta agtgcaacaa ccaaccgtaa
     7201 tcatgacttt tatgtattcc tgacccaacg ttacaatttg ggattcagcc gtgacatacc
     7261 gcaggccgaa aatgacacta ctcccgccaa acaagagttt gtgccggtca ctagttttat
     7321 acataccatt caggtagagc gtgcacgtca tagcttcaac tctgatgatg acatgcgtga
     7381 aaagaactat tatcaaaaca cctatttgga accggataat ccgattgcca gagacagtac
     7441 tacttatatg ggtatcaaga ataccatagg tattgctcta ctcgaaggat tcaataaata
     7501 tgccaaagcc ggactcacgg catttgcttc ctataaaatc agcaaatata ctcttatgaa
     7561 tatggagggg aatccattgc ccgacaaata caatgaaaat gaaatatttg ttggaggcga
     7621 attatccaaa cgtgaaggaa atgtacttca ttaccatgcc attggtgaag tgggactcgc
     7681 cggaaaagca atcggacaat tcaatgtaaa aggagatatc gaccttaact ttccgttatg
     7741 gaaagacact gtgagcctta tagcccgtgg tgaagtcagc aataagcttg cgcctttcta
     7801 tatgcgtcat tatcattcca aacatttcat gtgggacaat gatatggaca aagaatttcg
     7861 tacccgtatt gaaggagaat taagtattgc acgttggaga acacgtttga aggcgggagt
     7921 tgaaaacata aagaactaca cttatttcaa ccaacaagca gtgccggaac agaaaagcgg
     7981 aagtatacag gtgttgtcag caagtcttaa tcaggacttc aagctgggaa tcttccattt
     8041 agataatgaa gtaacctggc aaaagtccag cgaccagacc gtattacctt tgcctgatct
     8101 ttcgctgtat cacaatttct atatgcagtt caagctggca aagaaagtgc ttagtgtaca
     8161 attgggtgcc gatgtgcgtt atttcagtaa atacaatgca cccgcttata tgccggctat
     8221 ccaaaacttc tatttgcaac cggaaaatga ccaggtagag ataggaggtt atccgatcgt
     8281 gaatgtatac gcaaacttac atctaaagcg tacacgtttc tatgtaatga tgtatcacgt
     8341 gaatcaaggt atgagcagcc cgaattactt cttggctcct cactatccta tcaacccgcg
     8401 tgtactgaaa ttcggtcttt catggaattt ctatgattaa caaaatctat atggcttatg
     8461 gtaacacgcc ccaaattgag actggccaga tatttagtgc ccgtaatcat tgtattggca
     8521 atcatctttt ctatccgcca atgcggtaat caggaaaagc cgtcaggaca cccgcgtgat
     8581 tatgcagcca ttgccaaaga aggtatattg cgtgtagcga ctgaatataa ctcgatcagt
     8641 ttctacgtgg acggcgatac cgtttccggt tttcattacg aactgataca ggcttttgcc
     8701 catgacaagg gattaaagac cgaaataaca cccctgatga gtttcgaaga acggctggaa
     8761 ggattaagcg agggacgtta cgacgtaatt gcctgcggta tattagccac cagcgaactg
     8821 aaagactctc tgctcctcac ctctcccatc acgctcaaca agcaagtgct cgtgcaacgg
     8881 aaagaaaacg gagaaaacga ctcactccat atccgtagcc agctggactt ggccgggcgg
     8941 acacttcacg tagtaaaagg gtctccttct attctgcgta ttcagaatct aggtaatgaa
     9001 atcggcgata ccatttatat caaagaaata gagaaatacg gttccgaaca attaatctca
     9061 atggtagctc atggggatat cgactatgcc gtttgtgacg aaagcatcgc acgcgcggcc
     9121 gccgattcca tcccgcagat agatataaat acagctatca gctttacaca attctactca
     9181 tgggcagtca gcaaacaatc acccgcttta ctcgatagtt tgaatacatg gctggataaa
     9241 ttccaaaagg agaaagaata ccagaagatt tataaaaagt actatgataa agaataacct
     9301 tatcatttta cagttcagaa gaaaacaatc aaaaacagaa tgtaagatag atatattcat
     9361 gtctatttcc agaaataaac tcccaaagac ttgactttcg cttttgaatg tcgtatcttt
     9421 acagagttaa tgataaagta gtttcaatta aactacacgc aaaggaggga atcgcgattc
     9481 tctcctttct ttttatccag ccgggaaaaa cctctccccg ccccagcttt tccttgcgct
     9541 ttgcccggtg gttatggttc ttcagccgga ggatcagcag tgttcacctt gcttcttacc
     9601 gaaatgaagt atatatccgc ctcaaacaga cgttctgttt gcctgaaaca gagcctttgt
     9661 tccgataaaa tagagcttct gttgaaacaa aacacaatgt ctgttttcta actgtccctg
     9721 ctaagttaat aatcaataaa gttgctcttg acaaaaaata gctttatctt tggggtttgt
     9781 tagaacagac acaataggta tattatatta tgagtgaaaa gattatcaaa tggggcttca
     9841 ttggttgcgg agaagtaacc aagacgaaaa gcggtcccgc tttccagaaa gtagaacatt
     9901 cggaagtcgt agccgtgatg agtcgtgacg gcgcgaaagc gaaagcgtat gccaaagaga
     9961 gaggaatcaa gaaatggtat gacgatgcac aggagctgat agatgatccg gaagtaaacg
    10021 ctatctatat cgccactcct ccttcttcac acgctacgta tgccattatg tccatgaaag
    10081 cgggtaaacc ggcctatatt gagaagccaa tggcggtgac gtatgaagaa tgtacccgaa
    10141 tcaaccgcat atccaatgaa acgggggttc cctgtttcgt agcatactac cgacgttatc
    10201 ttccctattt ccagaaagta aaggaattag tagagaacgg aacgatcggc aacgttatca
    10261 atgtacagat tcgttttgcc cagccgccac gcgatctgga ttacaatcgt gataatcttc
    10321 cctggcgtgt gcaggctgat attgccggag gcggctactt ctacgacctt gctccgcatc
    10381 agattgattt gttgcaggat atgttcggtt gcatcctcga agcaagcggt tacaagagta
    10441 atcgcggcgg gctttatcct gccgaagata cattaagcgc ctgtttccaa tttgacaacg
    10501 gactggtggg tagtggttcc tggtgcttcg tagcccatga ttctgcccgc gaagaccgca
    10561 tagagattat cggcgacaaa ggaatgattt gcttctctgt ctttacttac gaacctatcg
    10621 gactgcatac cgagaaagga cgggaagaaa tctgtatcgg caacccggaa cacgtgcaac
    10681 agcctcttat ccaagcagta gtagaccact tattgggtaa gtcggtttgc tcttgcgacg
    10741 gcgaaagcgc aacgttgact aactgggtaa tggacaagat cttaggtaag ctataaccct
    10801 aaaaaaagca aaaaaaagtt ccttcttttt ccggattctg ccggtattgt taaaaaatta
    10861 atagggacat tccattgtat attgttagtt ttttctatct ttgtagaaag aagcaaagaa
    10921 aaaatgaaac taacaatata ttttttgtgc catgactaaa gaagctttaa tgagaaaagc
    10981 gatcgagctt tcaaaagaaa atgttgaaaa tggtggaggt cctttcggtg ctgtgattgc
    11041 cacgaaagac ggagaaatag ttgcaacagg agttaatcgt gtcactgcat cttgtgatcc
    11101 tacggctcac gccgaggtaa gcgccatacg tgccgcagct gccaaactcg gaacatttga
    11161 tcttagcgga tacgaaatct atacttcctg cgaaccttgc cccatgtgcc tgggtgctat
    11221 ttattgggca cgcctggata agatgtacta tggaaacaac aagaccgatg ccaaaaacat
    11281 cggcttcgac gactctttta tctatgacga actgcaactg aaacctgaag acagaaagct
    11341 gccttccgaa atcctactac ataatgaagc ccttactgcc ttcaaagcct gggtggccaa
    11401 agaagacaga gtagaatatt agaaaacctc tcactattat taacctatta attaccctca
    11461 aatgaaaaga aaaagccttt tatttgttat ggcatcagta tgcctgttca gttgtcaaca
    11521 gcaagaagaa ctgcaagacc ccagtaatgg agtgatcgac ttttctactt ctattgacca
    11581 aagtatcaac aatgctctta cccgtaacag cagtagtctg acacttccgt taaaaagcaa
    11641 tttcgctgcc ggggatgtta tctccatgtc cgttgccgag caggattatc atccgtttgc
    11701 cataggcatg gatagccaaa cctggaacga agcaggcacc gattcggaaa cggttacttt
    11761 ctatgctcat tatcctgaat tgaccgacga agctgctact accagatcat tgagcagccg
    11821 ctatcgtgaa atcaagggtg gcttagaata tttgttcggt acagcccaag ccaacaaagg
    11881 ttctaagagc gttgctcttg cattcaagag aatgacaacg cccgtcgttc tgctcgacga
    11941 gaacaaccag ccgtacgaag gtagagcaat cgttaaactg ttcttgaaga acaaaggtgt
    12001 gcaagacctg ttcagcggta aaatcgaagc tgaccccaat gcaaaaccgg aatacattga
    12061 tatccggaaa gtatctgaag gtatcttgac taacttgatt ccacagctca tcaaagccgg
    12121 cgagaaaata ggaacggtta tcctggagga cggtaaagaa gaacctatca tcgcagagga
    12181 ggacattacc atagaagccg gaactcctgt tgcggtaaaa atgtacgcaa gacgcggaat
    12241 cattgacgaa cgaactccac tattcagata agactaaaga ataaaaagtg atactaataa
    12301 aaatccccgg aaccgctgta gacactcagc attccaggga ttttttacac acaaaagtta
    12361 ttattgaaat tgaaaactgt cttttttagg ttagaaacgc atacctaaag taagaaccac
    12421 tttatggttg ttgttcgtca ctttcgttcc aggtaaatct aaactatcaa aagcatagaa
    12481 tgtttcttta taagtattat acatatatgc catgtctaca tagaaacttt caccacgata
    12541 gccacaaccc aatgtataat tattagtagc acccggatta gaaaattccg tatcagtacg
    12601 cattgaattt acaggaagat acttaaaagc atctgatttc aaaggagcag taatatgatt
    12661 atatcctaaa cggaatgcaa attccggtgc taacttaaat tcagctccaa cacgaagtgt
    12721 atgaactgct ttcatcattg ctttaatgtc ttctgtctga cctaattcat atccgtccgg
    12781 atctttcatt ttagctgaag tacggtctga atattcatac tcaactccca atgctacaga
    12841 agaaccgatg gtatatccca tacttgcatt aaacttccac ggagtaatta acttatattc
    12901 atattctcct tcagtatcat ttccacgggc atcataaggt ttggtaatgc cacgtgtagt
    12961 ctcattcaaa tcaaaattaa tataagcagt attccgttcc ttcaaactaa agaaagtcgg
    13021 agtatgtaca gcagcaccaa tacggaatga ggatgactca aaaggacgaa gaataaaacc
    13081 tagtttaaaa tcaactccac taccatctac ccaaaagtca tttcccaacg tatatcctcc
    13141 atgaccattt ccgtccttat cagtaaagtc ttcattatat tcactagtcc tgtcatagtt
    13201 tacactataa agtcctaatg ttgctccaac ataaaaacga tcataaaaat tcagcgcacc
    13261 attcaaatca aaagaatgga tacctccact ttctttcgaa cgataagact ggctcacagc
    13321 atctcctgcc tgaaaatagg gttcatatcc ctcaaaagga ggaactgcat ctggattctc
    13381 tggatctact ttcccataaa caggattcac taaatgtgca ttatatccca taatacccaa
    13441 ccaaggcaat tcaggattct gaaaagcatc atcgctcctc aaagcagctt ctgtgaacgg
    13501 atcaaagtct ctgtatgaat caaagttcac catattagcc atctgaactg tttgagaagt
    13561 attgaatact ccactcacca gcatacttct attgaaggac ttcattttgc gataattgaa
    13621 accaaagttg gcaaatctca aagcagttgt atttcctatt tttgtagaga atacaaatcc
    13681 ggcattatca aatgagccat gaaacttatc aagacttgcc ccattcgctt tcactcctgt
    13741 attatcaaag ccaaatgaaa ccataacatc attgctacga taaattccga taccggcagg
    13801 attagttcct atagtggtta tatctccgcc taaagctccc atggcaccgc ccatacctac
    13861 aaagcgggca gttccattta aatcacttcc catccatcga tttgcatcat agatagttgt
    13921 ttgagcattt agaaatccta cacttatcaa aagaatacaa atcgctaata ttctattact
    13981 tttcataatc aatctctttt gaaattataa actatcttct atagctacca ccagaactac
    14041 gtgaagaacc accaccgccg ctactacgtg aagaactgcc actgctgcca gaactacgag
    14101 aataactacc gctactacct gatgaatagc tacttccact acttcttgaa taactacctg
    14161 aattagaaga gcgggatgat gatctgtcag gcgtataact tcttgatgga gaagtggaac
    14221 ttccacgtga atagctacta ctgctacggc tactatttgt tccggaactt cgtgtcgaac
    14281 tattacttct attataagag gaaccagaat tgcgtgtact agtaccagaa gtacgtgtac
    14341 tgcttggacg tgtatacgtt tctgtatttc tacgagagta tgaacttcct gaacgaacag
    14401 agctattgct accgctacga gtataatcgc gagtacctac aactctacta tttgtacctg
    14461 tactacctga acggcgaaca ctttgtccaa cagaagaatt agctggtctg gtagttgatg
    14521 aaccgacacc tcttctgtaa gaagtagaat tataatttct cgaaccagaa taataggaac
    14581 gattattacc attaatcaca ctacgtccgg cataataagg tcttccacct ccgccccagc
    14641 cccagctagg accaccgtgc cagtggtgat gatgtcccca atatccgccg ccataccagc
    14701 caccccagta gccgcctccc caataaccgg ggtaatatcc ccaagagtaa taaggacgat
    14761 tccatcccca gccatagttc catccccagc cgtaagagcc ataacgccaa tcccaccaaa
    14821 gcgggttact gaacgtcggg aatgcataag catacatacc atcggtatat acgttccaat
    14881 cccatgagtt cggaccgtaa actacatccc agtacaacgg gctgctgata ctgatagcaa
    14941 aacgcggatt gcggaaacgg atgatacgtt cagcgtattc atagtcgtct gttgtaccat
    15001 tgaattcgcc cgtcacccat tctccgtcca aatccggatt agatttttct tttatatata
    15061 aggtatcatt atccattacg aattcatttt cacgtgcatc gtaacggcgg ttatattcat
    15121 ccacatcccg tgttcttccc ttacggtcct gaacaaccac tgtagtaccc ggtgaagtat
    15181 agatgttagt cgtcacctgt ttcttcggtt ccttcttaac tggagtttct ttcttctcct
    15241 gtttgtcttt ggaaggtacg aagtaaaggt cgtcatcaac gctttgtgca aagataccta
    15301 tcggaaggca caaggcaaat agcaagaaat aaacaatctt tttcatatca tctcggttta
    15361 tgtaattact taaacttatt cacgttacaa agataaggaa gagatttttc gtccggggga
    15421 gattttcccc aaaggataat agggaaatcc ctatttctaa ctatctttgt agaagataca
    15481 acgctcaccg gcataaagtt caggcaaact tgactttcta tacccggatt gctgtatctt
    15541 tgcacattat tcaccagcat taaaaacaac tatgaagtat tttgagttca cattccgcac
    15601 ccagccttgt accgaaaccg tcaatgacgt actggctgcc atattgggtg aagtcggatt
    15661 tgaaagtttt gttgagtgtg aaggcggact gaccgcatat atccaacaga cattgtgtga
    15721 tgaaaacgcc atcaagattg ccatcaacga gttcccccta cccgatacgg atattactta
    15781 tacatatacc gaagcggaag acaaggactg gaacgaggaa tgggaaaaga atttcttcca
    15841 acccatcatt atcggaaacc gatgtgtgat ccacagcact ttccaccaag atgtccccaa
    15901 agcggaatat gacatcgtca tcaatcctca aatggccttc ggaacaggac accacgaaac
    15961 taccagcctc atcattgaag aattattgga cagcgaactg aaagataaat ccctgctcga
    16021 tatgggctgc ggaacttcga ttcttgccat cctcgcacgt atgcggggcg cacgtccctg
    16081 tacggccatc gacattgatg aatggtgcgt acgaaactcc atcgaaaaca tcgagttgaa
    16141 ccacgtagac gatattgccg tatcacaagg agatgcctcg tcgcttgtag gaaaaggacc
    16201 tttcgacgtt atcatcgcca acatcaaccg gaatatatta ctgaatgata tgaagcaata
    16261 tgttgcc
//
