LOCUS       c00002_gnlPro..        25412 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOJPONKI_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 14:10:17
            Original ID  :: gnl|Prokka|AOJPONKI_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 150564
            Orig. end    :: 175976
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25412
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[160564:165976]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15412
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25412
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25412
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             593..1930
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_156"
                     /sec_met_domain="MmgE_PrpD (E-value: 2.9e-94, bitscore:
                     312.0, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQGLTAGLAAAVRTSQPEYSVDAIHEAKKGLLDFTAASFAGRE
                     DKGIQKLLRLIEDEGGRPLVPIIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPS
                     AVIVPALIASAARGHDERLLGAYIVGVEVMARLGESIGSRHYEKGWHNTGTLGAIAAAC
                     AVGYAEALTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFG
                     GSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAV
                     RQLISEETISATNTERIEVIFPPGGDAALTERSPKTGEEGRFSVEYVIALALHGHGLTV
                     EHFNSQPIPNGVQTTIRHIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRICEARVDCP
                     KGAPGNELSEEDIKEKLTLTVPQEKARRIITAVEKADIKEFLAHIE"
     CDS             2000..3112
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_157"
                     /sec_met_domain="EutH (E-value: 3.2e-139, bitscore: 459.9,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPLA
                     LSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPQA
                     GLFSWVFLGTMMGPAIVFTIPVALGIIEIEDHPYFAKGILIGLCTVPIGCFIGGLCAGF
                     DIGMIGKNLLIPSLLSAVIAFGLWRYTDRMIQLFHLFGKAVSVVAIIGLAAVSVETMTG
                     IVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKHLHLDETATAGL
                     VTSLAHHIPMLASLKNMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKL
                     AGGVTAAAAAAWMTPAQSAKQQKRISASHS"
     CDS             3185..4012
                     /locus_tag="ctg2_158"
                     /transl_table=11
                     /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMTA
                     AGAGRAKDSSGALQTLSRMPYGSLLLFLIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLS
                     RRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAGFIV
                     FAIVQFMKGVRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMT
                     ADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK"
     CDS             4146..5087
                     /locus_tag="ctg2_159"
                     /transl_table=11
                     /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLNISRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHE
                     TVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEA
                     FQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALLFRLG
                     YFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELQDLRLKERSILVAGGS
                     RKVSSIHGALTGKYANVLIIDQHTARALVNDL"
     CDS             5193..5864
                     /locus_tag="ctg2_160"
                     /transl_table=11
                     /translation="MSLANIIDHTALKPHTQKAEILKLIEEAKTYKFASVCVNPTWVEL
                     AAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDV
                     VEADIRGVVEAAAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     KEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDN
                     Y"
     CDS             5945..7126
                     /locus_tag="ctg2_161"
                     /transl_table=11
                     /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYI
                     LLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALI
                     GILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQ
                     RLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDM
                     LRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGIL
                     GYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFL
                     VSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY"
     CDS             7156..8457
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_162"
                     /sec_met_domain="Glycos_trans_3N (E-value: 2.5e-22,
                     bitscore: 74.5, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 2e-53, bitscore:
                     177.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAI
                     FFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDV
                     PVAKMSGRGLGHTGGTIDKLEAIDGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVV
                     LAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDEVIAKVYDNIRIAAEAKAPKLIHTLITE"
     CDS             complement(8498..9862)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_163"
                     /sec_met_domain="AA_permease (E-value: 4.7e-135, bitscore:
                     446.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLGGVIGTGLFLSTGYTLHQAGPGGTILAYVIGGLMMYLVMQC
                     LGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWINWVVTVGSEFTASGILMQRWFPD
                     SSVWMWSAIFAALLFICNAFSVKLFAETEFWFSSVKIVTIILFIILGGAAMFGLISLNG
                     TADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFAFSGTELIGVTAGESANPQKDIPRSI
                     RNVAWRTVIFFIGAVFILSGLISWKDAGVIESPFVAVFAEIGIPYAADIMNFVILTALL
                     SVANSGLYASTRMMWSLANENMISSRFKKVTSKGIPLNALMISMAVSCLSLVSSIVAPG
                     TVYVVMVAIAGFAGVVVWMSIALSQLLFRKRFLKKGGNVKDLTFRTPLYPLMPIAALLL
                     CSASCIGLAFDPNQRIALFCGVPCIILCYLIYHFKRSVTKAKKISQEEYQADHIL"
     CDS             complement(10001..10960)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_164"
                     /sec_met_domain="Arginase (E-value: 5.8e-68, bitscore:
                     225.4, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLS
                     KSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIAKSHHHI
                     FQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGP
                     TNGTPFRRLLDEEIIEGQHLIQLGIREFSNSQAYEAYAKKHSVNIHTMDMIREKGLIPT
                     IKEILPVVQDRTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVA
                     GIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK"
     CDS             complement(10953..12218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_165"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.7e-20, bitscore:
                     67.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQ
                     KIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLD
                     ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQL
                     RVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDEFLDQMLSLLPEIKEQELASFADIFT
                     ETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGELKAVSADHLVGASDEGI
                     KKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVCVSLATDFNPGSSPTENIQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKVGRSADLVIWQATNYMYIPYHYGV
                     NHVHQVMKNGTIVVNREGAILG"
     CDS             complement(12231..13889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_166"
                     /sec_met_domain="Urocanase (E-value: 2.1e-90, bitscore:
                     297.9, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 7.5e-96, bitscore:
                     315.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 1.9e-62, bitscore:
                     204.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVL
                     VPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWA
                     EEAKLAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYSLDEAD
                     RLRQDTPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPG
                     FVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTF
                     QGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARV
                     LTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK"
     CDS             complement(13886..15412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_167"
                     /sec_met_domain="Lyase_aromatic (E-value: 7.6e-197,
                     bitscore: 650.5, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERIV
                     RDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRAN
                     ALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFF
                     EGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIAS
                     LTIEGLQGIIDAFDEDIHSARGYQEQIDVAERFRFYLSDSGLTTSQGELRVQDAYSLRC
                     IPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKI
                     AISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYT
                     KQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI"
     CDS             complement(15525..15980)
                     /locus_tag="ctg2_168"
                     /transl_table=11
                     /translation="VIHMTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWRVCLGKV
                     GSMDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVG
                     LRFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             16496..17905
                     /locus_tag="ctg2_169"
                     /transl_table=11
                     /translation="MFNRLFRVCFLAALIMAFTLPNSANAQKPVFKEVSVHDPSIIETN
                     GTFYVFGSHLASAKTNDLMQWQQLTNSVSNDNPLIPNVYKELKETFEWAQSDTLWAADV
                     TQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSNDGTPYDA
                     TKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGNHSR
                     IEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVRGKE
                     GTFFDDRSIESYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIFHTRFPG
                     RGEEHEVRVHQLFMNKDGWPVAAPYRYAGETLKEVKQKDITGTYKLIQHGKDISADIKK
                     TINIQLNKNHTISGEMTGTWKKTGKNTADITLAGKTYNGVFLRQWDSVREKNVMTFSVL
                     NGSGEAVWGSK"
     CDS             18211..18576
                     /locus_tag="ctg2_170"
                     /transl_table=11
                     /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHEFSEAQHLI
                     HRPHLNREAWRGTHAQRFEDIREGMNKAYQQIKSDQVSGIIESIEGKIHSLEGDVYSIR
                     RQITRIEHEIEKEKHKK"
     CDS             18588..18857
                     /locus_tag="ctg2_171"
                     /transl_table=11
                     /translation="MAQEIKMVYGTVKQGLSQLKNSAELKSSLPGHLSGRNHLNVVKSI
                     EQLNKDIKELTEAYASVLAKHIAQTESAVNAMKETDENISSSMK"
     CDS             18877..20493
                     /locus_tag="ctg2_172"
                     /transl_table=11
                     /translation="LKTLDVHALHKGIQHTIEKLDKQKQQLEKLEKSLEHLAGMKDALK
                     GKGGDAIRTFYEECHKPFLLFFGMFIDEYKKVLKQTQHAISSVESDSHGMIAEAFLSHD
                     ARHGVKHAREVTEQLTDAVNRQTSAIGHIVSLPAVNDTFFRMETEQAERLISDTLNKLF
                     QFDGQQTQALETAKSDFQTMKKYMDQLETMYTGPKIEITGYKSGSILKSQEEENINQTF
                     GAINPQMKQADDSPMEMMLKKLEKHKQSNVDSVMMDDKQQKIEREIHADDSNLTVLQKE
                     AAAHLKVYGDIRVVNDKLYNHKGLKKIDTIEVIDELTRDTASIDYVGGKYYVYENGQIV
                     RELYAGGKKRLEEVSYIPEDKVGGAKPLDSFLAGTQYEFIEWVSPQGAVKKLAVRCGKR
                     VVTDVAKHVVEKDIKGDVKKKPSKGSVNSKWWHPGYVDNLSSSQTVIGIKNSPKGLSTL
                     GSSTRQNALDAGKGWVGQGAEKMYDKAGNFLGYKSVDKMRAFRLQYKPKEKMWRANFTE
                     NEITVVGSKTELRNVHVDILD"
     CDS             20510..20836
                     /locus_tag="ctg2_173"
                     /transl_table=11
                     /translation="MLEIKALTKDYENWGEDADDFYVSFELDVGLPDIPGASDLFTFNI
                     ISPKRLDKILESTKIELGHGYLIMRDFNIKTVNSTVETIMNKCKDDDYDKYMNNLAQYF
                     KLQG"
     CDS             21167..22624
                     /locus_tag="ctg2_174"
                     /transl_table=11
                     /translation="MFIDEYKKVLKQTQHAISSVESDSHGMIAEAFLSHDARHGVKHAR
                     EVTEQLTDAVNRQTSAIGHIVSLPAVNDTFFRMETEQAERLISDTLNKLFQFDGQQTQA
                     LETAKSDFQTMKKYIDQLETMYTGPKIEITGYKSGSILKSQEEENINQTFGAINPQMKQ
                     SDDSPMEMMLKKIGEKEGTEVDSLTAHNRLEQMIKNQKVTKKVYSEEDIKKLQKIYKTI
                     DGITYCAYIDGNIIVKIECVDESLEPDDNESDIERYLEMGLELFSADDWERAALGFDPH
                     THEKLSLLDRFKAGVNITPPAKVIKWIRRGNKLAKVSKKAEKATDEVSKVEKKERTAEK
                     VAKAEKKNSKSASKVKFSEMTADEQIKIAKEYSKRAPIRIPDAAKVKAQSKTDYEQITY
                     KWNDGTYKYEVRWHTSTPGAPKNQGNTWVVQKTVPGNGGQQPQRFFKIGENEWIEGHKW
                     FEAIRERKAGTATKDQLRILEKGHWKD"
     CDS             22630..22989
                     /locus_tag="ctg2_175"
                     /transl_table=11
                     /translation="LLNTKFYDGFEGEPELALSDGENKLIMWNGYFETLLKALLDNNLE
                     KEGIIKEYFYQEGWYDDSPWVIEDVQLAINQMKSFDVSKLVVSDGFKKELVELVQEIIQ
                     FLENAKNKTVVIEYD"
     CDS             23428..25257
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_176"
                     /sec_met_domain="PTS_EIIC (E-value: 1.2e-38, bitscore:
                     128.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYDKLSKDILQLVGGEDNVQRVIHCMTRLRFNLHENAKADRSQL
                     EQLPEVMGTNISGEQFQIIIGNDVPKVYQAIVRHSNLSDEKSAGSSSQKKNVLSAVFDV
                     ISGVFTPILPAIAGAGMIKGLVALAVTFGWMAEKSQVHVILTAVGDGAFYFLPLLLAMS
                     AARKFGSNPYVAAAIAAAILHPDLTALLGAGKPISFIGLPVTAATYSSTVIPILLAIWI
                     ASYVEKWIDRFTHASLKLIVVPTFTLLIVVPLTLITVGPLGAILGEYLSSGVNYLFDHA
                     GLLAMILLAGTFSLIIMTGMHYAFVPIMINNIAQNGHDYLLPAMFLANMGQAGASFAVF
                     LRSRNKKFKSLALTTSITALMGITEPAMYGVNMRLKKPFAAALIGGAAGGAFYGMTGVA
                     SYIVGGNAGLPSIPVFIGPTFIYAMIGLVIAFAAGTAAAYLLGFEDVPSDGSQQPALHE
                     GSREIIHSPIMGEVKALSEVKDGVFSAGIMGKGFAIEPEEGEVVSPVRGSVTTIFKTKH
                     AIGITSDQGAEILIHIGLDTVKLEGQWFTAHVKEGDKVAPGDPLVSFDLEQIKAAGYDV
                     ITPVIVTNTDQYSFSPVKEIGKVQTKEALLALS"
ORIGIN
        1 agatcgtcat caaagggaaa ggcgggcacg ccggcatccc aaataacagt attgatccaa
       61 tcgctgcagc cggacaaatc atcagcgggc tgcaatctgt ggtcagccgc aatatcagct
      121 cactgcaaaa cgcagtcgtc agtatcacaa gagtacaggc gggcacctcg tggaacgtaa
      181 ttccagacca agctgaaatg gagggaacgg ttcgaacctt tcaaaaagaa gcgaggcagg
      241 ttgttccgga gcatatgaga cgagtggctg aaggaattgc agcgggctat ggggcacaag
      301 cagaattcaa gtggtttcct tatttgcctt ccgttcagaa tgacggcaca tttttgaatg
      361 cggcatccga agctgcggca cggcttggct atcaaaccgt tcacgctgag cagtctccgg
      421 gcggagaaga cttcgctctg tatcaagaga agattccggg attttttgtc tggatgggaa
      481 cgaacgggac ggaggagtgg catcatccgg cctttacact ggatgaagat gcccttacgg
      541 ttgcctctca atactttgcg gagctggcgg ttattgtatt ggagaccatc aaatgagcaa
      601 acaagggctg acagcaggtc ttgcagcggc tgtgagaacg tcacaacctg agtattcagt
      661 tgacgcgatt cacgaagcaa aaaaaggatt acttgatttt actgccgctt cattcgcagg
      721 aagagaagat aaaggcattc aaaagctcct ccgtctgata gaggatgaag gaggccggcc
      781 ccttgttcct attatcggac agggcaaaaa ggccgcacca ttacaatccg cgatgctgaa
      841 tggatttatc gcccatgcat tggattttga tgatgtccac tccgatgtaa gaggacaccc
      901 cagtgcagtc atcgtaccgg cccttattgc atctgccgct cgcggacatg acgagcggct
      961 tcttggcgct tatattgttg gtgttgaagt gatggcacgg ctgggagaat caattggcag
     1021 ccgccactat gaaaagggct ggcataatac aggaacgctt ggtgccatcg ctgctgcctg
     1081 cgccgtaggt tatgctgagg cgctgactca ggaagagctg gaaaaagcaa ttggttttgc
     1141 ggctacacaa tctgctggga tgagggtgca atttggaaca gaaatgaaac cactgcacgc
     1201 cggtttggcg gctcaggctg gcttgctggc cgttaagctg gcccaatcag aatttggcgg
     1261 gtcccgcacg gcacttgatg gagaaactgg tttcttcagt ctgtacggtg acgttgaaaa
     1321 agcacaacat actttgctaa acgattgggg ggcaccgtgg agaattgtgc agccgggtct
     1381 atggtttaaa atctatccat tttgttccgc ggcacaccat gctgcagatg cggtacgaca
     1441 gcttatctcc gaagaaacca tttctgcgac caataccgaa cgtattgaag tgatttttcc
     1501 gccaggcgga gatgctgcat tgacggaaag atctccgaaa actggagagg aaggccgttt
     1561 cagcgttgaa tatgtgattg ctcttgcttt gcatggacac ggcctgaccg ttgaacattt
     1621 caacagccag ccgatcccaa acggcgttca aacgacaata aggcatattc agcgcgtata
     1681 tgacaatgct attcagccgg ctcctcatgc cgttccaaaa ggccgtttca cgattgtccg
     1741 ggcctattta tcagacggcc ggatttgcga agcgcgtgtg gactgcccaa aaggggcgcc
     1801 aggaaatgag ctgtctgaag aagacataaa agaaaaattg acattaacgg tcccgcaaga
     1861 aaaagcgcgg agaatcataa cagccgttga aaaagccgat ataaaagaat ttttagctca
     1921 tattgaataa gatcaactct attcgatgat ttcagatgat atgataaaac caattatacg
     1981 tttgaaaaag gagaaaacca tgacggtgaa tgacgcggtt gtattcattt tggctgcctt
     2041 tttactatgg ggagcggcgg attattgttt gggaaacaga tgggggctag gcgagcggtt
     2101 tgcggacggc tttaaggcta tggggccgct ggcgctgtcc atgatcggaa ttgtgtcgct
     2161 ggcgcccgtg ctggcagcaa tcctgattcc cattgttgct ccgttttaca cagcgattgg
     2221 cgcggaccct tcttcctttg ctaacaccat tttggcgatt gatatgggag gatatgcgct
     2281 ggctggagaa atggcgaaag atccgcaggc cgggctgttt tcatgggtgt ttttaggaac
     2341 aatgatggga ccggcaatcg tcttcacgat tcccgtcgct cttggcatca tcgaaataga
     2401 ggatcatccg tattttgcga aaggcatatt aatcgggctg tgcacagtgc cgatcggttg
     2461 tttcatcggc ggattatgcg cgggctttga catcggcatg ataggtaaaa accttctgat
     2521 cccgagtctg ttatctgctg tgatcgcttt tgggttatgg cgatacaccg acagaatgat
     2581 tcagttgttt catctcttcg ggaaagcggt cagtgtggtt gcgattatcg ggcttgcagc
     2641 tgtttcagtt gaaacgatga ccggcattgt gctgattccg ggaatggaga atgtcgagac
     2701 agggatacaa acgacaggga ccatcgccat tgccctggca ggggcgtttc caatgacggc
     2761 ttttattaca aaaaccttta aaaaaccgct tcaggccctg gggaaacacc ttcatttaga
     2821 tgagacagca acagcaggat tagtgacctc tttggcgcat catatcccga tgctggcttc
     2881 attaaagaat atgacgccga gaggaaaggt catcaatgtc gcgtttgcgg tcagcggcgc
     2941 ctttgtactc ggcagccatc tcggttttgt agctggaatg aaaaaagaaa tggcggcggc
     3001 catgatcatt gggaaattag caggcggagt cacagctgcc gcagcggctg cttggatgac
     3061 acctgcacaa tcagctaaac agcaaaaacg tatctcagcc agccatagct gaggcagaag
     3121 ctgtttcaac tttgtccaat cgggaatgtt acagtaaaga tttctgtgaa agagggttgg
     3181 acacatggcg gtgaaagacc ggtacatgtc aaaaataaaa caggaaacca agccttggat
     3241 caaacgattc gggaggcttg gttattttgc attcggcggc gtttttattc tgcttggggt
     3301 tttggctttt atgacggctg ccggggcagg ccgcgccaaa gattcgagcg gagctctcca
     3361 aacgctatca cgcatgccgt atgggtcact attgcttttt cttataggca tcggccttat
     3421 cggctatgtg atctggatgg tgttaagcgc gatcaaggac acagaggggc acggaaacag
     3481 caggcgaggc ctgtcacgga gaataggaaa ctttttcagt gccgccgttt acacatccat
     3541 cgcttggaat gccttgcgat ttgtgtttgg ccaaggggac ggcggcactt cagaacagac
     3601 gtggtccgct tatgtattgg cgcagccatt cggccaatgg ctcacagggc ttacgggtgc
     3661 gggttttatc gtatttgcga ttgttcaatt tatgaaaggc gttcgggctg cttttatgaa
     3721 agaatttgat acgtcaaaaa tgaacaaaca aatgatatgc atcacgaaaa acaccggacg
     3781 cgcaggcaat atcgcccggg ccattatttt ctctgctatc ggctactttc tcatcaagac
     3841 agccatgacc gctgatcccg acgacacaag aggctttgac ggcgcgctcg ccgaactcgc
     3901 gcagcagccg catggcaaat tgattctgtc tatattggca ttaggcctga tcctatatgg
     3961 aatgtacgcc attatgaaag gcatttatca gcatatgacc tgggagaagt aagctctggg
     4021 caggtccgcg cccagagcgt ttttcagttt cttagaaatc aggtggatga aagttggcgc
     4081 cagcctgtat aataaaagca aatcaaaagc agttttatca ggactgatcc acagggaggt
     4141 gcagaatgga tcgggaaaaa caacaattaa gcatagaagc ggcaaggctt tactatcagt
     4201 ctgactacag tcagcagcaa attgctgagc agctcaacat ttcaaggcca accgtttccc
     4261 ggctgctgca atatgcaaag gaaaaagggt atgtccagat tcgcgtcatg gacccttttg
     4321 aggatttgga tgcgctcggt tccatacttg aagagaaata cgggctcctt gaggcgcatg
     4381 ttgtgttttc cccgacaccc gattatgcag gaattacaca tgacctaagc cgctatggtg
     4441 cagaatatat gcatgaaacg gtaaaagacg gcgacattgt cggcgtcagc tggggaacca
     4501 ccatgtatca aatcgcacaa aacatgcagc cgaagcaagt aaaaggcgtc gaggtcgtcc
     4561 agctgaaagg cggcatcagc cattcccggg taaacacgta ttcggctgaa acgattcagc
     4621 tgtttgcaga ggcttttcaa acgatgccgc gctatctccc gcttcccgtc gtgtttgata
     4681 atgcggatgt gaagcgaatg gtggagaaag accgtcatat tgaacggatc attgagatgg
     4741 gcaagcaggc gaatatcgct ctcttcacgg tcgggactgt ccgtgacgaa gcgctgttgt
     4801 tccggctcgg atattttaac gaagaagaga aagccctgct gaaaaaacag gccgtcgggg
     4861 atatttgttc acgctttttt gatgcgaaag ggaatatttg cagcagcgcc atcaatgacc
     4921 ggaccatcgg tgttgagctt caagacctca ggctgaagga acgctccatt ttagttgccg
     4981 gcggaagcag aaaagtatct tccattcacg gagcattaac cggaaaatat gccaacgttt
     5041 taatcattga ccagcatacc gcgagggcgc ttgttaatga tttgtgacac gctcaaacct
     5101 ttcgttgaac aaaatttcaa ttaccaattt acatatgttc aaaagtcggt tatgctaaaa
     5161 aatatcttaa caaaaaagga agtgtgcgaa ggatgtcatt agccaacata attgatcata
     5221 cagctttgaa accgcataca caaaaagcgg aaattctaaa actaattgaa gaagcgaaaa
     5281 catacaaatt tgcttcagta tgtgtcaatc cgacatgggt ggagcttgct gcaaaagagc
     5341 ttaagggaac tggagtcgac gtttgtacgg tcatcggctt cccgctcggt gccaatacaa
     5401 ctgaaacaaa agcgttcgag acaaaagacg ccatttcaaa aggcgccact gaagtggata
     5461 tggtcattaa tattgccgct ttaaaagaca aggaagacga tgtggtggaa gctgatatcc
     5521 gtggtgtagt ggaagctgca gccggaaaag cgcttgtcaa agtcattatc gaaacgtgcc
     5581 ttctgactga tgaagaaaaa gaacgtgcat gccgtttagc ggtgtctgcg ggagcggatt
     5641 tcgtaaaaac atcaacaggc ttttctacag gcggcgcaac gaaggaagat atcgccttaa
     5701 tgcgcaaaac agtaggacct gatatcggcg tgaaagcatc tggcggcgtc agaacgaaag
     5761 aagatgtaga cacaatggta gaggccggag caagccgaat tggcgccagc gcaggcgttt
     5821 ctatcgtaaa aggagaaaat gcatcaggcg gagacaacta ttaagagctg acggaaggca
     5881 gactgctttc cgttttctga ggaaacagtg attgtaagcg aatacaaata aaggagaaac
     5941 acatatgaag tatttgattg ggattatcgg tttaatcgtg tttttaggcc tcgcgtggat
     6001 cgcgagcagc ggcaaaaaaa gaattaagat ccgcccaatt gttgttatgc tcattttgca
     6061 atttattctt ggctacattc tcctcaatac cgggataggg aattttctcg tgggaggatt
     6121 tgcaaaagga ttcggttatc tgcttgaata cgcggctgag ggaattaact ttgtgtttgg
     6181 cggcttggtg aatgcggacc aaacgacatt ctttatgaat gttctcttgc caatcgtgtt
     6241 tatttccgct ctgatcggga ttctgcaaaa gtggaaagtc ctcccgttta tcattagata
     6301 tatcggcctt gccctcagca aggtaaacgg tatgggaaga ttggaatcgt ataacgcagt
     6361 ggcttctgcg attttagggc agtcagaagt atttatctcc ttgaagaaag aactcggtct
     6421 tttaaatcag cagcgcttgt acacgctttg cgcatctgcg atgtcaactg tgtcaatgtc
     6481 gattgtcggc gcgtatatga ccatgctgaa accggaatat gttgtaacag cgctggtctt
     6541 gaacttattt ggcggtttca taattgcttc tattattaat ccgtacgagg ttgcaaaaga
     6601 agaggatatg cttcgtgttg aggaagaaga aaaacaatct ttcttcgaag tgctcggaga
     6661 atacatcctt gacggtttca aagtagcggt tgtcgtcgct gcgatgctga ttggatttgt
     6721 cgcgattatt gccttgatca atggcatttt taatgcagta ttcggtattt cgttccaagg
     6781 cattcttgga tatgtgtttg ctccattcgc ttttcttgtc ggtatcccat ggaatgaagc
     6841 tgttaatgcg ggaagcatta tggcaacaaa aatggtatcg aatgaatttg tcgccatgac
     6901 gtcgcttacg caaaacggtt tccatttcag cggccgtaca acagcgatcg tatcggtatt
     6961 ccttgtgtca tttgcgaact tctcctcaat cggaatcatt gccggtgccg taaaaggact
     7021 gaatgaaaag caaggaaatg tcgtcgctcg tttcggcttg aaattattat acggtgctac
     7081 gcttgtcagc tttttatcag cagcaattgt gggcttgatt tactgaactt aatcgaaaag
     7141 gatcggtgac caaacatgag aatggtagat atcatcatca aaaaacaaaa cggaaaagaa
     7201 ctcaccactg aagaaattca atttttcgtg aacggctata cagacggaag cattcctgat
     7261 tatcaggcaa gcgcgcttgc tatggcgatt ttcttccagg atatgagtga ccgtgaacgc
     7321 gcggacttga cgatggctat ggtgaactcc ggtgaaacga ttgatctttc tgccattgaa
     7381 ggaattaaag tggataaaca ctccaccggc ggcgtcggcg acacgacaac gctcgttctc
     7441 gccccgcttg ttgcggctct tgatgtgccg gttgccaaaa tgtccggccg cggcctcggc
     7501 catacgggcg gcacgattga taagttagag gcaatcgacg gcttccacgt ggaactgacg
     7561 aaggatgaat ttattaaact tgtgaaccgc gacaaggttg cggtcatcgg ccaaagcggc
     7621 aatttaacgc cggctgataa aaaactgtac gcgcttcgtg atgtaacggg aacggtcaat
     7681 tccattccgc tcattgcaag ctcgattatg agcaaaaaaa tcgctgccgg ggcggacgcc
     7741 atcgtgcttg acgtaaaaac gggagcgggc gccttcatga aaacagaaga agacgcagct
     7801 gaacttgcca aagcgatggt acgcatcgga aataacgtcg gccgtcaaac aatggctgtc
     7861 atttcagaca tgtcccagcc actcggcttt gcgatcggaa atgcgcttga agtcaaagaa
     7921 gcgatcgaca cgctcaaagg cgaggggcct gaggatcttc atgagcttgt cttaacgctc
     7981 ggcagccaga tggttgtgct tgcgaaaaaa gccgatacat tggacgaagc gagagcgaag
     8041 ctggaagaag tcatgaaaaa cggcaaagca cttgagaaat tcaaggattt cctgaaaaac
     8101 caaggcggcg acagctcaat tgttgacgat ccgtctaagc ttccgcaagc cgcatatcaa
     8161 attgatgtgc ctgccaaaga agcgggtgtc gtctctgaaa tcgttgcgga cgaaatcggc
     8221 gtcgcggcga tgctgttagg tgccggtcgc gccacaaaag aagatgagat cgatttagcc
     8281 gtcggcatca tgctccgcaa aaaggtcggc gacaaagtag aaaaaggcga accgctcgtg
     8341 acactttacg ccaaccgcga aaatgttgat gaagtcatcg caaaagtcta tgacaacatc
     8401 cgcatcgccg cggaagcgaa ggcgccgaag ctgattcata cgttgattac tgaataaaaa
     8461 aagcacatcc catcctgagt ggggtgtgct tttttgatta aaggatgtga tcagcctgat
     8521 attcctcttg gctgattttt ttcgcttttg taacacttct tttgaaatgg tagatcagat
     8581 agcaaaggat gatacaagga actccgcaga aaagtgcgat tctttgattg ggatcaaaag
     8641 caagaccgat acaagaagct gagcataata aaagagcggc tataggcata agaggataaa
     8701 gcggcgtgcg aaatgtcaga tcttttacat tccccccttt tttcagaaat ctctttcgaa
     8761 acaagagctg ggacaaggca atgctcatcc agaccacgac tcctgcaaat ccagcaattg
     8821 cgaccatcac cacatagaca gttccagggg ccacgatact ggaaacgaga gataaacaag
     8881 atacagccat actgatcatt aaggcattta aaggaatgcc tttagaggtc actttcttaa
     8941 aacgggagct gatcatgttt tcatttgcta acgaccacat catacgggtc gaagcatata
     9001 agcctgagtt ggcgacagac agcaaggctg ttaatatcac gaaattcata atatcagcag
     9061 cgtaagggat tccgatctcc gcaaatacgg cgacaaacgg gctttcaatc acgcctgcgt
     9121 ccttccacga aatcaatccg gataatatga agacagcgcc aatgaaaaaa atcacggttc
     9181 tccatgcgac attacggatg gatcgcggta tatccttttg aggatttgct gattctcctg
     9241 ctgtaacgcc gattaactct gtaccggaaa aggcgaagct cacagatatc atcgcgataa
     9301 aaacggcgag aaagccattc ggaaacagcc cgccatggtc cgtgaagttt gacaacatag
     9361 gagcatccgc cgttccgttt aaagagatca ggccaaacat ggcggctcct cctaaaatga
     9421 taaataaaat aatggtgaca atctttacgc tggaaaacca aaattcagtt tccgcaaata
     9481 acttaactga aaatgcgttg catataaaaa gaagggctgc aaaaatcgca ctccacatcc
     9541 atacactgct gtcagggaac cagcgctgca tgagaatacc ggatgcggta aactcagagc
     9601 ctaccgtcac cacccaattg atccagtaca tgatgccgac cataaaaccg gtagatggac
     9661 cgataaatgt tgtagcatat ttttgaaaag agccggttac cggcatggca accgacaatt
     9721 cgccgagaca ttgcatgacg aggtacatca tcaacccgcc gattacataa gcgagtatcg
     9781 taccgccggg tccggcttga tgtagcgtat agcccgtact gaggaaaagt cctgtgccta
     9841 tgacgcctcc caatgagatc ataaataggt gcctgctttt cattgtgcgt tttagctgtt
     9901 ggctgctgtt ctcctgaaga ttcactgtct cgccctcctt ttagctgcca ttcattaggc
     9961 agatgagttt cttataccca aaatacaacc tgccagaaga tcacttgaat ggggagagtt
    10021 tcattccttt taatgcgtgt aacagaacat gagctgcagc tctgcttgtc atatctcgaa
    10081 aatcgagggt agggtcgact tcaacaattt caatcccggc aacattgggc tgttgtgcga
    10141 tgtacttgac tgcttcaagc aattcgtctg tatagaggcc gcccgggcca atcgctggac
    10201 agccgggtgc atgggactgg tctaagacat ccatgtcaac agatataaaa atgaaatctg
    10261 ttctatcttg aacaacaggc aaaatctctt ttatcgttgg gattagtcct ttttcccgga
    10321 tcatgtccat cgtgtgaatg ttcacgctat gtttttttgc atatgcttca taggcctggc
    10381 tgttgctgaa ttctctgata cccagctgga tcaaatgttg gccttcaata atctcttcat
    10441 ccaaaaggcg gcggaagggt gtgccgtttg tcggcccccc gtcctccgta ttgcgaacat
    10501 cgtgatgggc atcaaattga atcaccgctg tcgttccttt tgtttgtgct atcgctttta
    10561 ttgtggagta gctgatagag ttatctcccc cgagtatgag cggcacccaa tccggatgat
    10621 ccgaaagcag agcgtgcatg gtttggaaaa tgtgatgatg tgactttgcg atatcagtga
    10681 catgaatatc gatatccccc agatcatata gaagctctga tacgacgtgc tctccaagct
    10741 cagcagaata ggctgatgaa tgtttcagag cctggcgtat tgttccgggt gcaaaggaag
    10801 cgcctgaatg actgatggag gattttgata gggggacacc tatcaacgcc ggtcccttaa
    10861 tgtcctgacc gtcccatgtt gcgatcaggt cgctcatttt tgtgacatcc cggtctttaa
    10921 acgaagatcc ggcctctctg agaaaagggt acttatccaa gaatggctcc ctccctgttg
    10981 acaacaattg ttccgttttt catgacttga tgtacatgat taaccccgta gtgatacgga
    11041 atatacatat agttcgtggc ttgccaaatg actagatcag ctgagcggcc gactttgagc
    11101 tgaccggctt cttctccttt ccctatggcg tatgcggcat tgactgtgac cgcgtgccat
    11161 atttcttctg cagtcatctt cagatgaagc gcggcaatcg acatgatcag ctggatattt
    11221 tcagtcggcg agctgccagg attaaaatcc gttgccaagc tgacacatac accttcatca
    11281 atcatagctc tagccctggc gtatgtgctt ttgccaagat aaaatgtcgt gcccggcaag
    11341 aggacggcga tcgttcctgc ctcagccaat ttctttatgc cttcgtccga tgcacctacc
    11401 aaatggtcgg ctgagacggc ctttagctca cctgctaatt cagcacctcc aagaggatcg
    11461 atttcatctg cgtgtatttt taatccgaag cccgcctcag ctgctttttg taaataacgg
    11521 cgggattggc tgactgtaaa aacgcctgtt tctgtaaaaa tatcagcaaa gctggcgagc
    11581 tcctgctctt tgatttccgg caaaagggaa agcatttgat ccagaaattc atctggatcg
    11641 ttttgatatt cgggaggaat cgcatgggct cccataaatg tggaaacaag gtcaacaggc
    11701 tggctttcat gcagtttctt tgcgacacgc aactgtttga gctctgtctc tttttccaag
    11761 ccgtagccgc ttttcacttc tgctgtggtt gtgccgtagg acagcattct ttgcagatga
    11821 aaatgggctt tttgcagcag ctcttcttct gaagccgccc tggtatcctt gactgtagac
    11881 agaatcccgc cgccctgcgc cagaatatcc aaatatgaaa tgccctgaag cttaaggttc
    11941 atctcctttt cacgagatcc gccaaataca agatgggtgt gcggatcaac gaggccgggc
    12001 gttacaaggc gtcccgaaca gtcaatgatt tcgtctgcct cgtaaccggc ttcagcccct
    12061 ttttgtccgg cgaacacaat tttctgttca tggatgccga caacagcgtc ttcgatcaca
    12121 tgaagatcct gcatgctttt gcctgcccgc ggaccgctgc tttccatcgt caaaagctga
    12181 ccgatgttga tgagaatcgt atcaatttgc tttggcatgt catcactcct ttatttttgc
    12241 atcggcacga taatgtcctg ttccttcgct acttcaacgg cacgttcata acccgcatcc
    12301 gcatgacgga taatgcccat tcccgggtcg ctcgttaaga cccgcgcgag ccgctcgtca
    12361 gccagttcac ttccatcggc cactgcaacc atgccggcat gcagggaata gcccattccg
    12421 acgccgccgc catggtggaa ggaaacccag cttgcacccg ccgccgtgtt gacaagcgca
    12481 tttagtacag cccagtcacc gacagcgtca cttccgtcct tcatcgcttc tgtttcccgg
    12541 tttggagagg cgacagaccc gcagtccaaa tgatctctcc caataacgac aggcgctttt
    12601 agctccccag ttctaaccag ctcgttaatg gcgaggccca tcttttttcg ttctccatat
    12661 ccaagccagc aaatacggga cggcaagcct tggaaggtga ctttttcctg tgccatatca
    12721 atccagcggt gaagggcttt atttgtcggg aacagctctt ttaataacgc atccgtacgg
    12781 taaatatctg ccggatctcc ggaaagcgcc gcccaacgga acggcccttt tccttcacag
    12841 aataaggggc ggatgtaggc agggacaaac cccggaaaat cgaaggcatt ctccagccct
    12901 tcatcctttg cgacttgccg gatattgttg ccgtagtcaa atacaataga gcccttttgc
    12961 tgaaaggcca gcatggcttc gacatgtttt ttcatgcttt gcttcgcaag gcgcacgtaa
    13021 agctctggag tgtcttgacg caaacggtca gcttcatcaa gggaatagcc ctcgggaaca
    13081 taaccgatta aagggtcatg ggcagatgtc tgatctgtca caatatcaat tttgacgcct
    13141 cggttcaaaa gtgtgtgatg cacctcagcc gcgtttccga gaagcgcaat ggacaaaggt
    13201 tttcctgcca gctttgcctc ttcagcccaa gctaaggctt cctcaatcga tgctgttttt
    13261 cgatcgcagt attttgtttc gatccgcttg tcgatgcgtt tctcgtcaac ctcgacggca
    13321 atcacgacgc cttcattcat cgtgactgac agcggctggg cgcctcccat tccgccgaga
    13381 cccgctgtca gcgtcaacgt tccttttaag ctgcccccga agtgctgtcg cgccagctca
    13441 gcgaaggttt cataggttcc ttgcaatatg ccttgtgagc caatgtaaat ccagctgcca
    13501 gccgtcatct gtccgtacat catcaaccct tttttctcaa gttcgtggaa atgctcccag
    13561 tctgcccact tcggaacaag aacagaattt gctaagagca cgcgcggggc ctgcgggtgt
    13621 gtacggaaca tgccaacggg ctttccggat tgcacgagca atgtttcatc attttttagt
    13681 gttttcaagg aatgctcaat ggcgtgaaaa gcgtcccaat ctcgtgcggc tttgccaatc
    13741 ccgccatata cgatgaggtc ctccggcttc tcggcgactt ctggatcaag gttgtttcga
    13801 agcatccgaa gcactgcctc ttgctcccac cctaagcatt caagctctgt tcctctgttg
    13861 gcacggattg atttttttac atcagtcata tgttcatccc ccttagttct ttattctgat
    13921 ggtcaggtat taaagattcc ttcttcagcc agtcagtcaa gcgttcaatg tcataggaaa
    13981 aaacacgatc ctgctgaatg gacggcacga cttttctcat ttcttgaaaa agctgtttcg
    14041 tataggacgc tgcatgttct atgcctctgt attcaacagc ctgcaatgcg caaatcgctt
    14101 cgatcgcaat gactctcctt gtatttgcga tcacctgata agcatgccga gcggcgatgg
    14161 ttcccatgct gacatggtcc tcttggttgg cggatgacgg aatggaatcc acacttgcag
    14221 gatgggccag tgttttattt tcagaaacga gtgaggccgc ggcgtactgc atgatcattg
    14281 caccggattg cagaccggga tgagggctca ggaacggcgg caggtcattc agctgcggat
    14341 tcacaagtcg ttcgatccgg cgctctgcga tattcgcaag ctctgatatt gcgattttca
    14401 gaaaatccat ggcaaaggcg atcggctgtc cgtgaaagtt tccgccggaa atcactttgt
    14461 caccgtcatt gaaaatgagg ggattgtctg tagctgcgtt catttcaatc tctaattttt
    14521 ctttgacata gcctagtgtc tgccaagtcg caccgtgtac ttgcggaata cagcgcaatg
    14581 aataggcatc ctgaacccgc agttctccct gggaggttgt caggccgcta tcagatagat
    14641 aaaagcgaaa tcgttctgcg acatcgatct gctcctgata gccgcgggct gagtgaatat
    14701 cctcgtcaaa tgcatcgata attccctgca acccctcaat cgttaagctg gcaatgcgtt
    14761 ctgtttgata ggctagtttc tcagcttcga tgtaggcgac cacccccatt gcagtcatgg
    14821 cctgagtccc gttaatcaag gcaagccctt ccttggatgt cagcgttacc ggttgaatac
    14881 ctgctttttt caagcctgtc attgccggca ttctttcccc ctcaaaaaag acttctcctt
    14941 gtccgatcag cgcaagcgcc aggtgggaaa gcggcgccag atctccgctt gcgccaagtg
    15001 atccctgctg ggggatgaca ggatggacgc gtttatttaa aaaagcaagc aactgttcga
    15061 tcagctcagc gcggacaccg gaaaagcctt ttaacagcgc attggcgcgc aaaagcagca
    15121 ttgccctgga aacacactca ggaaaagggt cgccgactcc gcaggcatga gaaaggatta
    15181 aattcaactg cagcgccgcc gagtcttctt tctgaatcag gacatcgctg aatttgccaa
    15241 atccggtgtt gatgccgtag attgtctttt cgtcgcgtac aatccgttcc actgccgctc
    15301 tgcttttttt cacgcgctcc atactttcct cagaagccgc tgcctcctca aaatcaaaca
    15361 gcacacgagc gacgtcggct gttgtcaatg aagaaccgtc taaagtcacc ataagcccaa
    15421 ctcctttttc tttactttgg taaagcgccc atacaaaaag gagctatgct gtgaacttct
    15481 gtttccacgc atagccccct atcgtctaag atctatgggc tgtttcatat gtgattaatt
    15541 ccaacaccga atgtctcgtg ctcaagacct ttaatcggcg ccccgattgt tccgtaaagc
    15601 gagacagcaa tccaatcgcc ttccgcttca ctttcataag gatttcccct caaaacggca
    15661 aacctcaagc ccaccgtccg aagcagcgat cccagcagca tttcacctct ggtcacgcca
    15721 tgcaaagcct ccatcgtcgc atgataaagc gcatgtgact cccgataacc ctcagattga
    15781 atgacaccgc tctttttgga agcggtttca attgcggcta ctactttatg cgcgtccatt
    15841 gatcctacct tgccaagaca gaccctccat ccgtctcgct ccagctcctc aacctgcgta
    15901 ctttcttccg cctcattcag cagcaggaga acagacagcc ggccgatccg acgctcttta
    15961 tgcagtgtca tatgaatcac tcaattccta aaaattctga taactattaa ctgagtatta
    16021 tattaattgg ttcagcagca gaagtcaaaa gattttttac agtctttaac aagttagatt
    16081 gctattgtaa tagcgcgacg cagaaagccg cacattgcac acgaataccc agacagaagt
    16141 gcaagcggcc gctgtcatat tgctgacaat gagaggtaaa atgccaaaaa gaggcgaagt
    16201 tgccggagaa aagtcgacga tacaagaccg gacaaagcgt tcattacgta cgtaaatgaa
    16261 gaaacagaag taattgaaga aggagaaacg gcaaaagggt tgaactatga atagaggata
    16321 tgcaagcagc agttctgtgc caaacagaca tcagtctgac aatgtaagag aacagtgaga
    16381 aatcacctat ctgtttgaat atgaaaacat gcggctgttt taataggccg gtgtttcttc
    16441 atagagaaat gtaagcgctt aaaaaattaa taaaaaagag aggcgaattg tttagatgtt
    16501 caaccgattg ttccgtgtat gttttcttgc agctcttatc atggccttca ccctgccaaa
    16561 ctccgctaat gcacaaaaac ccgtatttaa agaagtcagc gttcatgatc cttccatcat
    16621 tgaaacaaat ggcacctttt atgtttttgg atctcatctc gcttcagcaa aaacaaatga
    16681 cctcatgcaa tggcagcagc tgaccaacag cgtaagcaac gacaacccac ttatcccgaa
    16741 tgtctataaa gaattaaaag aaaccttcga atgggcgcaa tccgatactc tttgggcggc
    16801 tgacgtcacg cagctggcgg acggcaaata ctacatgtac tacaacgcct gccgcggcga
    16861 ctcgcctagg tccgccatgg gtgttgccgt cgctgacaac atcgaagggc catacaaaaa
    16921 caaaggcatc tttttgaaat caggaatgga aggcacaagc aacgatggaa caccgtatga
    16981 cgcaacaaaa catccgaatg tcgtcgaccc gcataccttc tttgataaag acggcaagct
    17041 gtggatggtg tatggatcat actcaggcgg cattttcata cttgaaatga atccgaaaac
    17101 gggcttcccg cttcctggac agggatacgg gaaaaaactg cttggcggca accatagcag
    17161 aatcgaaggc ccgtatgttc tctacaatcc agacacccaa tactactact tatacctatc
    17221 atatggcggt cttgatgcaa caggcggcta taacatccgt gtggcccgct ccaagaaacc
    17281 agacggccct tattatgatg cagaaggcaa tccaatgctt gatgtccgcg gcaaagaagg
    17341 cacattcttc gacgaccgtt ccatcgaatc atacggcgtc aaactcatgg gcagctacac
    17401 ttttgaaaca gaaaatgaaa aaggcaccgg gtacgtctca ccaggccaca actccgcata
    17461 ctatgacgaa aaaaccgggc gttcctattt aatcttccac acccgcttcc cgggcagggg
    17521 tgaggaacac gaagtcagag tccaccaatt gttcatgaat aaagacggct ggccggtagc
    17581 agcgccctat cgttatgcgg gcgaaacact gaaagaagta aaacaaaaag atatcacagg
    17641 aacatacaaa ctcatccagc acggaaaaga catctcagcc gacatcaaaa aaaccatcaa
    17701 catccagctc aacaaaaacc acaccatttc cggggaaatg accggaacat ggaagaaaac
    17761 cggaaaaaat acagccgaca tcacgttagc gggcaagacg tataacgggg tatttttacg
    17821 ccagtgggat tcggtgagag agaagaacgt catgacgttt agtgtgttga atggcagcgg
    17881 tgaggctgtt tggggatcta aataagatgg agaagcgcct tcgagggaag gcgttttttt
    17941 atgattatta ttgactaaaa gtaacagtta agcacgaggg tgaatgtaaa tgatagtgag
    18001 attgaagacc tgaattaaaa gtccctgttg tgattattca ccctcatgcg aaattgtaaa
    18061 aaacgtattt ttagcaaatt agaactggta taactcccct caagacaatc ctttttacct
    18121 atttatccaa tatgacccat catgtaatat gaaaatagtc tgtattgtaa agaattgaca
    18181 cagtttgata gaaacacgag gtgttgcggc atgcatagtg aaatgttgtt acattcggta
    18241 aaagccgact tacatgaaaa gcaggaacag atccatcaat taaaacgagt gctgcacgaa
    18301 atcaggcaaa tcaaacacga attctccgag gcccagcatc tcattcaccg gcctcatctt
    18361 aaccgggagg catggagagg aacacatgct cagcggtttg aagatattcg tgaaggaatg
    18421 aacaaagcat atcagcaaat caaaagcgat caagtcagcg gaatcatcga aagcatagaa
    18481 ggaaaaatcc actcattaga gggcgatgtc tattccataa gacgccaaat tacgaggata
    18541 gagcatgaaa tagagaagga aaaacataaa aagtgaggtg agcacaaatg gcacaggaaa
    18601 ttaaaatggt gtatggcaca gtgaagcaag ggctttctca gctcaagaat tcagctgaac
    18661 tcaagtcctc cttacccggc catctctcag gcagaaacca tttgaatgtt gtgaagtcca
    18721 tcgagcaatt aaataaggac atcaaagagc tcactgaagc atatgcgtct gttctggcca
    18781 agcatatcgc acaaacggaa agcgcggtaa acgccatgaa ggaaacggac gaaaacatat
    18841 catcttccat gaaataaagc gcgggaggac aagggattga aaacattaga tgtccacgct
    18901 cttcacaagg gcattcagca tacgattgag aaactggaca agcaaaaaca acagttggag
    18961 aagctggaaa aaagccttga gcatctggca ggcatgaagg atgcgctgaa aggaaaaggc
    19021 ggagatgcca tccggacctt ttacgaggag tgccacaagc cttttctcct tttctttggc
    19081 atgtttatcg acgaatacaa aaaagtgctg aaacaaacac agcatgcgat ttcctctgta
    19141 gaatctgact cccacggcat gatcgcagag gcttttctct cacacgatgc gagacatggg
    19201 gtcaagcatg cacgagaagt gacagagcag ctcactgatg ccgtcaatcg ccagacatca
    19261 gccatcggcc acatcgtcag cttgccggca gtcaatgata cctttttccg aatggaaaca
    19321 gaacaggctg agcgactgat ttcggacacc ctgaataagc tctttcaatt tgacggccag
    19381 caaacccaag cactagaaac cgcaaaatca gattttcaaa cgatgaaaaa atacatggat
    19441 cagctcgaaa cgatgtacac aggcccgaaa attgaaatca caggctacaa aagcggctcc
    19501 atcctgaaat cacaggaaga agaaaacatc aaccaaacct tcggcgcgat taacccgcaa
    19561 atgaagcagg cggatgattc tccgatggag atgatgctga agaaactgga gaaacataag
    19621 caatcaaacg ttgattctgt gatgatggat gacaaacaac agaagatcga gcgcgagatt
    19681 catgctgatg atagtaactt aacggtatta cagaaagaag cagcagccca cctgaaagtc
    19741 tatggagaca tacgggtggt aaatgataaa ctatataatc ataaaggatt aaaaaagata
    19801 gatacgatag aagtgattga cgaactaact cgtgatactg caagcatcga ctacgtcggc
    19861 ggcaaatatt atgtatatga aaacggccaa attgtgagag aactctacgc tggagggaaa
    19921 aagcggctag aagaagtgtc ttacattcca gaggataaag taggcggagc taagccactg
    19981 gattcatttt tggctggaac gcagtatgaa tttattgagt gggtaagccc tcagggtgct
    20041 gttaaaaaat tggcggtccg atgcgggaag cgtgttgtca cagatgtggc taaacatgta
    20101 gtggagaagg atataaaggg agacgtaaaa aagaaacctt ctaaaggcag tgttaatagt
    20161 aagtggtggc atcctggata tgtagataat ttaagctctt cccaaacggt tataggaata
    20221 aagaattccc ctaaaggttt atcaactctt ggtagctcaa cacgtcagaa tgcactagat
    20281 gcaggaaaag gctgggttgg tcaaggagcg gaaaaaatgt atgataaagc aggaaatttt
    20341 ttagggtaca aaagtgtaga taaaatgaga gctttcagat tgcaatataa accaaaggaa
    20401 aaaatgtgga gagcgaactt cactgaaaat gaaattactg ttgtaggatc aaaaacggaa
    20461 ttaagaaatg tacatgttga tattttagat taaaaggtgg gatataatta tgttagaaat
    20521 taaagcttta actaaagact atgaaaattg gggtgaggat gctgatgatt tctacgtttc
    20581 atttgaactt gacgtaggat tgcctgatat accaggtgct tctgatttat ttacttttaa
    20641 tattattagt cctaaaagat tggataagat acttgaaagt acaaaaattg aattaggtca
    20701 tggatatctc ataatgagag attttaatat aaaaactgtc aattctactg tagagactat
    20761 catgaataaa tgtaaagacg atgactatga taagtatatg aataatttag ctcaatactt
    20821 taaattacaa ggataacacc aaaagagttg ttggctagtc gcttatagtt atactaaaag
    20881 aatatgaata tatcggaact gtaatcaatt tcgaatttaa tatacatgtt atatgataaa
    20941 caactagagg tttttcatgt tagaagatat tcctggttat aaaaatctca cgtcataact
    21001 attttaatta aatggttttc aggaccctct ggtttgcttc ctagtgagta gctttagaag
    21061 tgtagtggta actgttttac cttgattggc aaagtgcctt tcaaggtttt ttaataaaaa
    21121 taatctttta tagctaattc ataaaccctt tcaccttttc tttggcatgt ttatcgacga
    21181 atacaaaaaa gtgctgaaac aaacacagca tgcgatttcc tctgtagaat ctgactccca
    21241 tggcatgatt gcagaggctt ttctctcaca cgatgcgaga catggggtca agcatgcacg
    21301 agaagtgaca gagcagctca ctgacgcagt gaatcgccag acatcagcca tcggccacat
    21361 cgtcagcttg ccggcagtca atgatacctt tttccgaatg gaaacagaac aggctgagcg
    21421 actgatttca gacaccctga ataagctctt tcaatttgac ggccagcaaa cccaagcact
    21481 agaaaccgca aaatcagatt ttcaaacgat gaaaaaatat atagaccagc tcgaaaccat
    21541 gtacaccggc ccgaaaattg aaatcacagg ctacaaaagc ggctccatct tgaaatcgca
    21601 ggaggaagaa aacatcaacc aaaccttcgg cgcgattaac ccgcaaatga agcagtcgga
    21661 tgattcaccg atggagatga tgttgaagaa aataggagag aaagaaggta ctgaagttga
    21721 ttcgctgact gcccataatc gcctagaaca aatgataaag aatcaaaaag tcaccaagaa
    21781 agtatatagt gaagaggata taaaaaaact acagaaaatt tataaaacta ttgatggaat
    21841 aacttactgt gcctacatag atggaaatat aattgtcaag atagagtgtg ttgatgaatc
    21901 tctagaacca gatgacaatg aaagtgatat agagagatac ttagaaatgg gtttggagtt
    21961 atttagtgca gacgattggg aacgagcagc attaggattt gaccctcata cacatgaaaa
    22021 actctcactt ctagatcgat tcaaagctgg tgttaatata acgccgcctg ctaaagtgat
    22081 caaatggatt cgacggggaa ataaactagc taaagtgtct aagaaagcag aaaaagccac
    22141 tgatgaagtt tcgaaagttg agaaaaagga gagaacggca gagaaagttg ctaaagcaga
    22201 gaagaaaaac tctaaatcag caagtaaagt taaattttca gaaatgacag ctgatgaaca
    22261 aataaaaata gctaaagaat attccaagag ggctccaatt agaatccctg atgcagcaaa
    22321 agtaaaagct caatcgaaaa ctgattatga acaaataact tataaatgga acgatggaac
    22381 atacaaatat gaggtcagat ggcacacaag tacgcctggg gcgcccaaaa accaagggaa
    22441 tacgtgggtt gtacaaaaaa ctgttccggg aaatggtgga caacaaccac aaaggttctt
    22501 taaaatcgga gaaaacgagt ggattgaagg acataaatgg tttgaagcta ttagggaaag
    22561 aaaagctggg acagctacta aagaccaatt aagaatttta gaaaaaggtc attggaagga
    22621 ttgatcgagt tgttaaatac aaagttttat gatggatttg aaggtgaacc tgaacttgcc
    22681 ttatctgatg gagaaaacaa gctcatcatg tggaatggat actttgaaac tttattaaaa
    22741 gctttattag ataacaatct agagaaagag ggaattatta aagaatactt ttatcaagaa
    22801 ggctggtatg atgactcacc ttgggtaata gaagacgtac aattagcaat aaaccaaatg
    22861 aaaagttttg atgtaagcaa actagttgtt tcagacggtt ttaaaaaaga attagtagaa
    22921 ttagttcaag agattataca atttcttgaa aatgcaaaaa acaaaactgt tgttattgaa
    22981 tacgattaaa tctagaagct gggaagccag cttctttttg aagtttgata taatttgatt
    23041 tgagaaaacg gaaaactata atatttccaa gcctaaaggt ttatattaaa tctatttgtt
    23101 attattctca aaataatggt tggaagttct cattcttgaa aaataaattt atcgacatat
    23161 tgtaatagag gaaaatgaaa gcgttgacat cccgcaaatc tagtgctaaa gtatacctac
    23221 aaacaaataa aacgacccgt caggattgtt actgcgaaag caggcaaaac ctaaatggtg
    23281 caggtgcagg aggagactct cgcaatctgt gtcatttagg ttttttttat tctcttttag
    23341 gaggtgatgc agcatttgat agaaaaaaag ctggtgaaag gcggccacct ttcatccagc
    23401 agtcccccat aaaaaggagg tatacacatg gattatgata aattatcgaa ggacatatta
    23461 caactcgtag gcggtgaaga caacgttcag cgcgtgatcc actgcatgac gaggctgcgt
    23521 tttaatcttc atgaaaacgc gaaggcggat cgcagtcagc tggagcagct gcctgaagtg
    23581 atgggcacca atatcagcgg cgagcagttt caaatcatta tcggaaacga tgtgccgaag
    23641 gtgtatcagg cgattgtgcg gcacagcaat ctcagtgatg aaaagagcgc tggttcatcc
    23701 tctcagaaaa agaatgtgct gagtgcggtc tttgatgtga tttctggtgt gtttaccccg
    23761 attctgcctg cgattgcggg agcgggaatg atcaaagggc ttgtggcgct ggcagtcacg
    23821 tttggctgga tggcggagaa gagccaggtt catgtcattt tgacggctgt cggtgacggt
    23881 gcgttctact tcctgccgct cctgctagcg atgagtgcgg cgagaaaatt cggaagcaat
    23941 ccgtacgtcg cggcagccat tgcggcggcg atcctgcatc cggatttgac agccctgctc
    24001 ggtgcgggga aaccgatttc ctttatcggg cttcctgtaa ccgctgccac ttattcgtca
    24061 acggtcatcc cgattttgct ggcgatttgg attgcttcgt acgtagaaaa atggattgac
    24121 cgttttacac acgcatctct caaattgatt gtggttccga cattcacgct attgattgtc
    24181 gtgccgctga cattgattac agtcggtccg cttggcgcta ttttaggaga atacttgtct
    24241 tctggggtca attatttgtt tgatcatgca gggcttttgg cgatgatttt gctggcggga
    24301 acgttctctt taatcattat gacgggcatg cactatgcct ttgtgccgat catgatcaac
    24361 aacatcgctc aaaacggcca cgattattta ctgccggcta tgtttttggc gaatatgggg
    24421 caggcgggag catcatttgc cgtcttcctt cgctccagaa acaaaaaatt taaatcactc
    24481 gcgcttacca caagcatcac ggcgctgatg gggatcacag aacctgcgat gtatggcgtg
    24541 aatatgcgat tgaaaaagcc gtttgcggcc gctttgattg gcggtgcagc cggtggcgcg
    24601 ttttacggca tgacgggtgt tgcttcctat atcgtcggag gtaatgcagg tctcccgagc
    24661 atccctgtct ttatcggccc aacgtttatt tacgcgatga tcggccttgt gattgcgttt
    24721 gcggcgggaa cagcagctgc gtatttgctt ggattcgagg atgtgccttc tgacggcagc
    24781 cagcagccgg cactgcatga aggcagcaga gagatcattc acagcccgat tatgggagaa
    24841 gtgaaagcct taagtgaagt caaagacgga gtgttttctg ccgggatcat gggaaaagga
    24901 ttcgccatag agcctgaaga aggagaagtt gtgtcgcctg ttcgtggaag cgttaccacc
    24961 atttttaaaa caaaacacgc aattggcatt acgagtgatc agggagctga aatactcata
    25021 cacattggat tggacacagt gaagctggag ggacaatggt tcacggctca cgtcaaagaa
    25081 ggcgacaagg tcgcaccggg agatccgctc gtgtcctttg atctagagca aatcaaagcc
    25141 gcgggatatg acgtcattac cccggtgatc gtgaccaaca cagaccaata ttcattttcg
    25201 ccggtgaaag agatcggtaa agtacagaca aaagaagcgc tgcttgcttt atcttgaaaa
    25261 aactaatggg gtgatcaata tgagttcaaa cgcaaaacga tttccagaag gatttttatg
    25321 gggcggcgca gttgctgcca accaagtgga gggtgcttat aacgagggtg gtaaggggct
    25381 ttcgacagct gacgtatcgc cgaacgggat ca
//
