LOCUS       gnlProkkaPKNEEJFP_80   17044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKNEEJFP_80.
ACCESSION   gnlProkkaPKNEEJFP_80
VERSION     gnlProkkaPKNEEJFP_80
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:06:28
            Original ID  :: gnl|Prokka|PKNEEJFP_80
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17044
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17044
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4618:7044]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4619..7044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..17044
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17044
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             509..610
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKENDFLKKAAAFFAKEID"
     CDS             780..1049
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="MQWKEVNQFFETESIKLSDIEPSKVSYREVQRNQINTTIYNEKGN
                     IKDIDTSIIRDMYDKSKPTLKQGAYISAIAASLEGGYCIYNSNN"
     CDS             1209..1508
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MCTASFGIAKEAYKFRKNLITKEEFLLNSQILCVEVSVSALSSIL
                     GHAVIPIPILGSVIGNNIGTFLYEIAKDNLTMKEKLLIADYFKEIQEYNYFLDN"
     CDS             complement(1608..2519)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_4"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(2749..2838)
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(2835..3437)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_6"
                     /sec_met_domain="TIGR04085 (E-value: 4.3e-16, bitscore:
                     49.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.3e-13, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGVRAC
                     SINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCSECP
                     LPWCGGGCRCSALKLDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(3531..4622)
                     /locus_tag="ctg34_7"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             complement(4619..5809)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_8"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-07, bitscore: 22.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-20, bitscore: 64.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-14, bitscore:
                     43.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLKFATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQ
                     NARKHVAKLKKHNILSFPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQA
                     KDNGVLSVSILGGEPTRYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYIT
                     PVLSLQTLDPKLNFELMGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFC
                     IENKIDRFSVANYSEVTGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLF
                     TAYPELINNSIEFSEFGEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDL
                     LDVWYDDPLYGGIRSFRTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(5778..5939)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_9"
                     /sec_met_domain="Streptide_RRE (E-value: 6e-15, bitscore:
                     46.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEICYVLF"
     CDS             complement(6009..6152)
                     /locus_tag="ctg34_10"
                     /transl_table=11
                     /translation="MLKRNIITVSYSKGVPNMSKELEKVLESSSMAKGDGWKVMAKGDG
                     WE"
     CDS             complement(6184..7044)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_11"
                     /sec_met_domain="TIGR01716 (E-value: 1.8e-51, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             complement(7284..8120)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 264.5; E-value: 1.5e-80)"
                     /gene_kind="other"
                     /locus_tag="ctg34_12"
                     /transl_table=11
                     /translation="MVTEFSLDMLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIF
                     TEHKGNYGYRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAE
                     NLIQRQFEASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQV
                     KAMLEQAFTEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESF
                     FGILKSEMFYCYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(8114..8356)
                     /locus_tag="ctg34_13"
                     /transl_table=11
                     /translation="MGRFLTGSHTIRKTGTIVEKTRGRLSKMGRKPKKKLEEMERLQAE
                     NEYLRAENAVLKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(8301..8678)
                     /locus_tag="ctg34_14"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYYC"
     CDS             complement(8857..9015)
                     /locus_tag="ctg34_15"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(9027..9158)
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVYDKAVYWIYSGVKGQYEY"
     CDS             complement(9168..9800)
                     /locus_tag="ctg34_17"
                     /transl_table=11
                     /translation="MKSLSISSSFFSISTSSTPQLTANSIGQHSTAKQSRKEIELAAAK
                     LVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTSQNDAM
                     NQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTETRTVNL
                     NYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPSLPNTTTK"
     CDS             complement(10080..13259)
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 497.1; E-value: 1.9e-150)"
                     /gene_kind="other"
                     /locus_tag="ctg34_18"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDRFQKSLEERLRQSNKDMDKRQAQIDSHFASQVWSE
                     EELAVLASTPASEKLARLEEFLSQRQESLTEQKSILKAAHEDLAQLQKSFQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELAIQSEDFLQKEEELETWKEDIIYSQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLMIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVTKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIRKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(13256..14482)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.4; E-value: 8.6e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_19"
                     /sec_met_domain="Metallophos_2 (E-value: 1.7e-10, bitscore:
                     31.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEVVMKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEK
                     VDGVIISGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFF
                     QHQGLHLSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYIL
                     EDMEKAFDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFD
                     YVALGHIHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLE
                     VKRPIVALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTD
                     IVEITFSRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESV
                     FEEIERSRQ"
ORIGIN
        1 gataattgac ggtaaaatga caatcctgga gaagtaattt aatttatgac taaaaatcag
       61 caaaaatata attatgacta aggaatatat tattaactaa atgttgagat agcacaagga
      121 aatatttgtg ctatcttttt tatttattag gaaaagagaa aaaattatgc caacgaaaat
      181 atggttaaaa ccagaacaat tagatttgta tattaaacat ttagaacgat ttagagactt
      241 atatagtaaa ctagactgtt ctggtatagt aaatttgtaa cactcctacc taataagtta
      301 aactattcat tagaatagga gacataacat gaaacactat ccagacgaaa cacgataaaa
      361 aattgttcga ctgcacattc aagacggatg aacattaaaa agcttagctg ctgaatatgg
      421 cgtatcccaa gcctcaatct ctaattgggt aagacattat cgcaaagaat gccaaactaa
      481 taataaagaa aaatcacagc ttgaactcat ggaggaggtt cgtaaattac gtcaagaaaa
      541 ggcagagctt gaaaaggaaa atgatttctt aaaaaaagca gcggcattct ttgcaaagga
      601 aatcgattag aggcatatcg ttttattgat aactataaag aagattttgg tttgcgttgg
      661 ttgttcttgc atatgaatat tcatcccaat gcttattata attatcttaa aaagacaagg
      721 actaactatc atcgtcaaaa gaaagctatt cttaatacta ttcgagatat ctaccatgag
      781 tgcaatggaa agaagtaaat caattcttcg aaacagaaag catcaaactt tctgatatag
      841 agccttcgaa agttagttat agggaggtac aaaggaatca aatcaatacc actatttata
      901 atgaaaaagg taatataaag gatattgata ctagcattat aagagatatg tacgataaaa
      961 gcaaacctac tttaaaacag ggagcctata tatccgctat agcagcttct ctagaagggg
     1021 ggtactgcat ttataacagc aataattaaa aaaagcgctt agggaaaact attagtgagt
     1081 ttacaaaaga cgattgtctt gaaatttcta aagatagtgg aattggagct ataaaaggaa
     1141 gtactcgagg cattacgata tacgccctaa cgaattacac agctactcct gcagcagtag
     1201 caagttcatt gtgcactgct tcatttggta tcgctaaaga agcatacaaa ttccgtaaaa
     1261 acttaatcac aaaagaagaa tttttactaa attcgcaaat attatgtgtt gaagtatcag
     1321 ttagtgcatt atcctcaata ttaggacatg ctgtaattcc aatacctatt ttaggatccg
     1381 ttattggaaa taatatagga actttcctat atgaaatcgc taaagataat ctcacaatga
     1441 aagagaaatt actgatagca gattatttca aagagataca agaatataac tattttttag
     1501 ataattaatt tgaattatat aatcatcaac ttcagagaga ttaagaatta ctataaactt
     1561 ttagggaagg cattttctcc tgactataat atcgcttttc agggatctta tgaattttta
     1621 aatatgtttt ttaaaaatac gttaacctct cctattttct ctgcttcagg taaatagata
     1681 gaaacggttg tcgaataaac aaaagaaggt acactcacaa ttgaaagcaa ttgactaata
     1741 actgcataaa tagccaacaa ttctactcct aatctcgaca tcaaggcatc aaacaccata
     1801 ataaacaaaa cactctccag aatttcttga ccaaccaaag gaataccaaa tgttattaat
     1861 tcaaatttag ttgtagatgt aatggataaa gccttcaaaa tcattggata aaccataaac
     1921 aagtaactaa gcgatatgaa agctaaggat acaatcgttg atatggctgc tcccttaatt
     1981 ccgatttgtg gtaccagtac ataatttaac acaacatcta ttaatgaact gataagtcca
     2041 acccacataa ttggttttgt tttcttttga actcttaata aatttgtcag cgaaaagttt
     2101 aataatgtca atccgatata tggagacatg aagactaaat aaatggtgga taaggacaat
     2161 agttgccctt taaatccata gagctgcttc aagattacat ttccaaaaat aatgacaaaa
     2221 accgcaaagg caactccgat aattaaatct aaggttagat ttgatttcaa taaatcatca
     2281 aacctgttag tttgccgatt agagtacgcc ttagagcttt taatattaaa tgacaaactg
     2341 aatgctccta aaagtccacc aaaagcaaat aagagattct gaataatgga aattcctgac
     2401 agagcaattg aggaattgtt cacagcaaaa tgcaatgcta tctgcccaat aattacttga
     2461 ccaatatttg ttaaaactaa gggaaaggca aatttgttaa tttcttttga atctatcatt
     2521 tttcctctct aaaaggcttc aaatgtaagt aaagatcaga tttaactaaa tttgcataaa
     2581 taatatgcaa aataggagtt tcttctaaaa atgaaataat tgcctgctta caatcattag
     2641 cagatacctc ataatcttgc tgtaatagtt ctacaatctt gtctaaagaa aaatttttag
     2701 aaatgcaata aagtatttct gctcctattt catcaaatga atagtactct aatcaagtag
     2761 atcgtatcct atgtattcat ctgctacttt atttacaatg aaatctctct tacctcttat
     2821 cacaaaatgt tctttcatac gactactcca cctccttttt gttcataaaa gcaggctaaa
     2881 tcagagccca gtaacgttcc atctaatttc aaggcactgc atcgacatcc cccaccacac
     2941 catggtaggg gacattctga acatttccca gaaatatcat caaatgtaat tgatcttagt
     3001 ttattaaata cagcagaatg gtgccaaatt tcgctaaact tttgttcttt aacatttcca
     3061 gcaactaatt catctatacc attcatcaag tcacacccgt atacatctcc tttatgatta
     3121 attgaacatg ctctaactcc agcttgacaa gatatttccc ttggcttatc aaaatttata
     3181 tctacttttt gatgccaaac attttctaat aaatctgatc tattataaaa tgcaagcgga
     3241 aaataatgtg tcaaaaaaac atcactttca ttaggaggaa caattttaaa tttaactttg
     3301 aactctcctt tagaaatccg ctctgttaaa tcaagaaaaa caggatacca ttgtttttta
     3361 tctgctaaaa tactaccgtc attagcccta ccagtaggac aaataaccat aactgacata
     3421 tactcaatac caagcatatc attcaatctt atactctaaa gaaaatatct gctaaatttg
     3481 caaacaattg tgctatcaat aatttggcaa atgaattaga aatacaactt ttaagttctt
     3541 ttctctctgt tagaaaatga ataagatact aagcaacaaa gagctactat accaaatatt
     3601 aaataattgc tcctaatact aaagttatca gcaaaaatac cagctaggaa atcagctaac
     3661 ataaaactaa tcgaaataaa caaattatat actgaccatg atactgctct atttttttct
     3721 attgacatat taaatttata ataaaaatga ttattgtagt tggaattaag aacacgcatt
     3781 aataaaagga ttataatttg gatgattaga ttagtttgaa aaaacatgag tatagctaat
     3841 actggtaaca tcaagcttac ttcaaactta atttttagat aactccccaa agccatagat
     3901 atattaaaca taaatagtat aattcccagc atatctagtg aaagtccctg ttcatttaag
     3961 aatatccctg cataagaatt gctaatcata attagagttg agaatgctac tcctaatatt
     4021 attaataacc atggaatatt ttgaatatta tcgaggctaa aaaatttttg tttattattt
     4081 tgttcctttt taatctcggg taatcctatt aaatataata aactgaaaat tacaaataca
     4141 atggatataa taataggata aatataattc ctatgcaata aaggtggaga tataatcgta
     4201 ataatagcaa taaaaatata ttttaatgtg ttgagatttt tcaaaaatga tttatataca
     4261 acttcgtcat caattatttc aaaattataa gaaataagaa ctcctgaaga taatgattct
     4321 gacaatccaa aaaatatcgc tgaaatatat attatatttg attttccaaa caataggccc
     4381 cataatgcta aaattaataa taaatttgaa atagccaaaa ttttcttgta accaatctta
     4441 cttgaaatat aacttaaagg aatatcaaaa actgagccac atagctcagt aataactgat
     4501 aaagtagcta tttctgtgaa cgaaaaacct aagtgcttta atagtaaaat tcctacaaag
     4561 tagtacggta atccagatag aaacatattc attccgtata aattaaaaat cttcttactc
     4621 ataagttaca aactgggtct ctaaaatatt ttggactctt ctccttaatc aagttaacat
     4681 agcagccacc ctcgcaaatt tttaacaatc cacaagataa acacttagaa ttcttcgttc
     4741 taaaagaacg aatccctcca tacaacggat catcatacca aacatctaac aaatcttttt
     4801 caaaggcatt ctgcttagtt tgattaactc ctaaaaaagc aatgcaaggc aagatatccc
     4861 cattagacat tatttccatc ttagtatatt ttgcacgaca tccataatac atttcgccaa
     4921 actctgaaaa ttcaattgaa ttatttatca actccggata agcggtgaaa agatgacatc
     4981 cctcagtagc aaaatttaaa ttagcttccc gttgagttat ataatctgta acatactcat
     5041 tcaaccttct caaatcagct aaatcgtatt ttttctttat tttcgtatat cctgttacct
     5101 cagaataatt agctactgaa aatctatcta ttttattctc tatacaaaaa tcaaccaatt
     5161 ctataatctg ctcatagctt tgctttgtat acactgcatt aattctacat ttttttccaa
     5221 cctctttaaa gtacttcgct aatttaattt gtctatcagg tctcaccccc attaattcaa
     5281 aatttaattt aggatctaaa gtctgcaaag ataaaaccgg tgtaatatat ttagatttag
     5341 ctagaatttc cactgtactt ttctttatta attgggcatt agttgttata gtagtcttta
     5401 tcttcagttc ttcacaagct atcaacaaat tatcaatatc aaaatatcta gtcggttccc
     5461 ctcctaaaat tgaaacactt aacactccat tatcttttgc ttggcgcaaa attctttccc
     5521 aatctttagc aggtttggca tttctatctt cacgatttgc taaaaaacaa aaaccacatt
     5581 ttaaatcaca gtacatactg gggtatatta ctagttcaag cggaaaactc aatatgttat
     5641 gtttttttaa ttttgctaca tgctttctcg cattttgaag agtctcgtca ggatttttcg
     5701 atgatccctc aatattatta tcagaataga tatttaataa gagtactcgc tctagtttcc
     5761 ctgcttttat ttctttctta aaaaaggacg tagcaaattt caaaaccatg attttgaacc
     5821 aaataaagaa aataagcttc actctcatct aactcaattc ggtcaaaagt tactttattt
     5881 atcaaaattc caccaaactt ttctagtcta aataaaaaat cttctgaaat tgtcatcata
     5941 ttgaatacct ttctaaaaaa gcagaggaaa atatagcctc tgcttaactt atgggataaa
     6001 ttactttatc actcccagcc gtcacctttt gccatcacct tccagccgtc accttttgcc
     6061 attgaactag actcaaggac tttttcaagc tctttagaca tatttggtac tcctttcgaa
     6121 tatgatactg tgattatatt tcttttcaac acttacaata aaatattccc atatttgcat
     6181 tttctaacta ctagctaaaa ttttttctaa atgtccttca taagtctttg ctaagtgatg
     6241 acttcctgct aatttcatcg ctccaacaca cttcttcatt tcaataattg ctttcacatt
     6301 tccatcctct ttatattgat aaagattttg tgcatactta aagactaaac gttcatatac
     6361 ttctgtctca ataaaaaagc attgatttag ctgcttttca aaatataaag catccataaa
     6421 tttttctctt tcaacacatg taatatatcc atttaaaagc atcgttgaaa ttaatcgtct
     6481 gttatttgga atttctttgt aaaaatcaga acgcctaaac atttctcttg ctaagaccat
     6541 gaaaacatca tgatttaata catctaaagt attcgagaaa atcaataact catagtaccc
     6601 ccagtattct acactaaaga gataatctgt taaatatgtc aaatcatcct ttgtatagta
     6661 agtttctcct gataaatcct gtagacgaat tttcaataaa ataatattga tttgatgaaa
     6721 tttttctcgc ctatcttcca gttccatctg agaataaagt aattttttca taccttctac
     6781 gtcacgtgtt gacacaaaat gacgtacttt cgataacagt tcgtttaact catctctatg
     6841 aaaatcatgg accgcataca taaattcatc tattggcata ttgatttcat ctaaaataaa
     6901 catgaacttt gaaatcgtta aatctgtttc tcctttctca aatcgagaga gctgagacgt
     6961 tgatatacca gcctttgcga cgtcttttaa tcgtaatcct ctcgattctc gaaacttttt
     7021 aaaaatttct ccaaattttt tcatactaca cctccatcac gcatatatgg gaataatttt
     7081 catttgcttt catcatatca tacaataaag aaaaacaaaa gtgaggatta tcacatgaaa
     7141 aagcaaattt tactaacact tcttcttgtc gtatttgaag gcattatcgt tatcgtcgtg
     7201 ggataaagag tctgggacaa aagtccttta gctccaaaaa gcaacggcat aatgtactga
     7261 ccccaaaaag ttagacaaat aatttaagta aaggatttag ttctgtattg tacaggactg
     7321 agtcctttta gttttacctt aatgcgtttg ttgttgtaat aattaatata gtctgcaatt
     7381 gcttgttcca aatgctcaat tgacttaaac gtcttctcat aacaataaaa catctcagac
     7441 ttaagaatgc caaagaagga ttccatcatg ccgttgtctg gactattgcc tttacgtgac
     7501 atggatggtt ggattccttt ctcctctaaa aaatgatgat agaaatcatg ttgatattgc
     7561 catccctggt cactatggag aattgtattt ttgtaatgtt tctctgtaaa ggcttgttct
     7621 aacatagctt tcacttgtat caagttcggt gacttagaaa gattgtaggc gataatttca
     7681 ctattgaagc catctaaaat tggcgacaaa tagagttttt ggctgcttgc tggaatggca
     7741 aattctgtta catctgtgta gcatttttcc aatggtttgg atgcttcgaa ctggcgttgg
     7801 atgagattct ctgctttcat accaacctct ccttgatatg aagaatactt acgtttacgg
     7861 cgaattctag cggttaaacc aagtactttc ataagacgtt gaactctctt atgattaatc
     7921 acaattcctc gatttctcaa ttcaagagtc attcgacgat agccgtaatt tcctttatgc
     7981 tcagtaaaaa tggcttgaat ttcagcttta atgtcataat ccttatcatt ttgatccagc
     8041 tgttttaagt ggtaataata ggttgaacga gcaagcttaa taatctttag aagcatatct
     8101 aaagaaaact cagttaccaa tcctcggaca atttccgttt ttcttcttgc tctttttctt
     8161 ccctcaatcg gagttctctc aactttttaa gaactgcatt ctccgctcta aggtactcat
     8221 tttctgcttg aagacgttcc atttcttcca gttttttctt tggcttacgt cccattttag
     8281 ataaccttcc tcttgttttc tcaacaatag tacccgtttt tcttatagtg tgcgagccag
     8341 ttaggaagcg tcccacgatt tgggagagca tattcaagag aaactctatc ttgagaatag
     8401 cctttatata ggactttatc aatcatttct tgttttaatt caggagagta gtaacgattc
     8461 tttccttttt tagcgatttc tattccgtat cgatcaatca atttaatcat gtagctaaga
     8521 ttagaaatgt ttatcccaaa tttatttgaa agctgatcta agctatatcc ttggtttcta
     8581 agttcataga tttgaacctt atcttcataa gtcaatttca taataaaaac accccgaaag
     8641 ttagattttt tctgtctaac ttttggggtg cagttcataa aaccgttgct ttttgcatga
     8701 ttgtgataga cttggtgaaa tagaattgac caaaaatctt ctgaaatata acaagagagt
     8761 gactcgaatt taaaaagcta gagttccaca attggaaatc tctagctttt ttgtgactga
     8821 gaactttttg tcccagcctc tactttctac tgactactat cctgcatgcc ctaagtcgag
     8881 atagagaata tctcgcttag tggcatactc tagcgcatgt tcaacagcct caaataaatc
     8941 tgaagctaga aaccttttcg taaagacggt ttcgtcttta cgcttaaatt tcgcaacata
     9001 actatgttta gtcatttttt ctccttctaa tattcatatt gtcctttaac accactatag
     9061 atccagtaaa ctgctttatc ataaacttgt ttaaaggaga tacctaatcg attggctaca
     9121 tcaagaattg aaatttgctt acattcctct atattcataa aatatcatca ttttgtcgta
     9181 gtattcggca atgatggaac agatgaggat tcttctaaag ttttaggagt tgccttatct
     9241 agatcatcta acccagattt ccaaacctgt acttggttga ccaataactt accaggtagt
     9301 ttcgaatagt tcaaattaac cgttctggtt tctgtttggt ttgtctttga ttggttggca
     9361 ttctttaaat cagatacata agttacatta taagagacca tggcaatggc ttgattcgta
     9421 gtctgattga caaagatatc tgctttttca aaatgataat ccaaaatata gtccttatac
     9481 acttggttca tggcatcatt ttgacttgtc aattcttgag aataggccga ttcagtcata
     9541 taaggttgaa tacgtgtatt attttcccct agtttttctt tcgtatagta ctgtgtcaaa
     9601 aattctttta cagtatctga tgataaaata cttgctttat cttctgcttg tttgtcctct
     9661 acaagtttag ctgcagccaa ttcgatttct tttcgacttt gtttggcagt agaatgttga
     9721 ccaatagaat tagcagtaag ttgtggtgtt gatgaggtgg atatactaaa aaatgaggag
     9781 gaaattgata atgacttcac ctagctaaaa gttcaacgaa ttagggagac attaggtagc
     9841 ctcatattac cttgattagt ttttgctata acattgtcaa atatgatgac aaaaaaatcc
     9901 gtccgcactt ttttacgagt aggacgaatt aaatatgtta tacaaaccat cagcttttta
     9961 acaattctac ataaggtagt tgttaatgca actacctttt ttctatgttg attagaacaa
    10021 atttgacatg gctacaactg cgattatctg atatagagta ttatataaac tgattcctcc
    10081 taccccttat ccacaatttt aatacggcta ctgccatcgt gcgacttgat gataactagt
    10141 tgctgagcaa taccttcttt catatcgtcc acgtggctga tgacaccgac catgcgattt
    10201 tcaccgattt gttctaggac agagatagcc ttagtgaggg cttccttatc aagtgaaccg
    10261 aaaccttcgt cgatgaagag tgcttcaaca acggcaccct tgctggtatt ttggacaact
    10321 tctgagaggg atagggcaat ggccagtgca gcgataaagg tttcaccacc agacaaggat
    10381 ttaacggagc gttcactacc tgtcagctgg tcatagacgt tgatatccaa accgaagtga
    10441 tcacgcgccc tgcgtccttc ctcacttaga acaaaggaat agcggttatc cgttaatagt
    10501 ccgatgtagt tagcattggc atagtccaag atttgttgga aatactgacg gataacgtag
    10561 acctcaagat taagacgacc agttagagca gtattttctc ccttaaccac cttaaccaaa
    10621 tcactgagtt cttggtgggc cttaaaggcc tcttggttgc tgtcttgaag ggttttagcc
    10681 gcttggtagg tagccgtcgc atccttaagt cccttttcca tgacagaaaa ctgagcgagc
    10741 tgcctatcat agatttcctg acaattctgt actgcttgcg ctagactatc gagatctggt
    10801 tgttcttgat tttggagaag ctcttgcccc ttacgaatct gcgcctgtaa ttcttgtttg
    10861 agcgttgcat aggtcgttaa tttggcctga agcataggaa tagcttgatt atttacctca
    10921 ataagccaga gttcgacctg ctctaagtca ttggcgaggg ctccttcagc cttgagactt
    10981 tgctctaatt cagcagataa tcgcttaaca tcttgattta ccttatcttt agacttagtt
    11041 atactctcaa tctgcccctt gattccttta atgtcggcat gaagttggtt gtaggcttcg
    11101 ctattttcct tgacttgctt attgtagagg ttcagctcct gatgagcaag ggaaatccgt
    11161 tcttgatata cctcaacaga ctcaagttct ggatgagctt cctgcaagtc ctctaggcgt
    11221 tcttgagctt ggtcaagcac tgccttggcc tcttgatagg ttttagccaa atctgtcgct
    11281 tttttttgag ccttacctag ctcatcttga tatcggatat aatctgtctc ttccttatca
    11341 taacgttttt gtaactcttg ataatactgc tcaaccttca ggagtagggc ttgcccacgg
    11401 tcagtttcat agtctatcga aaaatcaaaa tcaaaccgtc ccttaacgtg ctcttctaat
    11461 tcttgatagt gcttttcaag agttgccttg actttagtca cttggtcaag caaatcctga
    11521 cgtttagatg caacttcact caaggtagcc tgacgatttg ataaagtagc gacttgcttt
    11581 tctttttgag cttgaagctt ctccacctga tccatgagat ttttcaaggc cacttcatca
    11641 gcctgtgctc caccaacatt agggtgttcc agagcaccac aaaccataca aggatgcccc
    11701 tcctctaact ctgcctgcag ttggacaatc atgagttgac ggcgtgaaac caaagtcctt
    11761 cttaactcct cttccaattc tttgagaatt tcttgagctt gatcaatatc aaaagataac
    11821 gtttgatgac gtttttcggt ctttgtcaac tcctgattca agttctctat ctctttcagg
    11881 tcctgagcaa gttgattctc cacactgtag cccacaatct ggaagagttt ttcggcctca
    11941 tgtaaactct ctaaactaag acgattagcc tccaagtcag acaaggactt gttaagcatc
    12001 tcaacctctt ttctagcctg ctgataggtc tcttccaact gcttgtagtt agtcgttgaa
    12061 cgtttgattt tctcctgttc ttgggcaaga ctctgggaat agataatatc ctctttccaa
    12121 gtttcaagct cctcttcttt ttgaagaaaa tcctcagatt gaattgcgag ttcctctttt
    12181 ttagccttaa catcctcaaa cgcctgttgc ttttcactta aggcttcttg agcaatttca
    12241 aggtcctgct ctaattgcat caactgtttc cgatactgct tcaaggtccg aatggtttcc
    12301 tgcagacctt gagcaaactg taattcctcc agatgcactt ttgcctctgc ctgtccttga
    12361 gccccctcct caatttccag acggtaacgt tccttggctt gctccaattc ttgaaaaatc
    12421 tttgccaaat cttgggcagt ttggaagctc ttctgcagtt gtgccaaatc ctcgtgggca
    12481 gccttcaaga tacttttttg ctccgtaaga ctttcttgac gctgagacaa aaactcttca
    12541 agacgtgcca atttttcaga ggctggcgtt gacgccaaga cagctaattc ttcctccgac
    12601 caaacctgac tggcaaagtg gctatctatc tgagcctgac gcttatccat atccttattg
    12661 ctctgacgaa gacgctcttc caaactcttt tgaaaacggt caaagatacc tgtcccaaag
    12721 attttcttta aaatttgagt cttagtcttg gaatcttcct tcaaaaaacg gctaaaatca
    12781 ttttgcggta agaggataat ctgtttgaac tgctcagcat tgagccccaa aatctgctca
    12841 atctggtcac tcacttcctt gatcttatcc ccaagctttt caatttcctg accaccaatc
    12901 ttatccacaa tgactagaga agccgtcgcc ttttgcatgg tagtgccccc accctgcttg
    12961 gccctctctt gctggagaac tcggtcaatg cgataaaggt gattgccttg ttggaaatag
    13021 aaagtcacct tggtcaaatc atcctctgga ccagcgaaag ttgaccgcat ctcctcaaca
    13081 ttacgatcac cactggtcgt agcaaacaag gctaccgtca tggcatcaaa gagagtactc
    13141 ttaccagccc ctgtatcccc tccaatcaaa aagaggggag catggtcaaa ctgagtgaaa
    13201 ttaataactt ccttacgata tggtccaaaa ttggtcaatt ctaactggac tggtctcatt
    13261 gtcgactcct ctcaatctcc tcaaaaacac tttccacaag ggcagtctgt ctctcagata
    13321 agacatcgcc cccagttact gtctggtaaa aatcaaatac gatttcctgg ggcgactgca
    13381 tttccaaatc ttttaagtgc tgatcaacgg tcaagttttc ttccctaaca tcacccagac
    13441 gactgaaagt aatttctaca atgtctgtcc cataaatctc ttccagtcgg gcacgcacat
    13501 tgataccctc taattcctta cgactagaca gttgaatatc aaaggcgaac caggcttttt
    13561 gacaaggttg attcttataa aattcaggtg acatcaaggt ttcaaaagat tcctgtaaag
    13621 ccacaatcgg ccgtttaacc tctagagtat ggaaggtctg agacatatca ccagacgcat
    13681 ccaattcaag aatatagaca cccttttctt ccttacgctt ggcttctttg acattaaagg
    13741 cgactggact gcctgaatat tgcacgcgct tggtaggact agcaaaacgc gtatggatat
    13801 gccctaaggc aacataatcg aaagacttga aaaggtcact ggtcacattg gtaagaccac
    13861 ctaccgtatt actggtttca gacaacatca attctcgaag accctgacca tcgctatcat
    13921 ccttcttaga aaccgcaaaa tgcgtcacca agacatgagc tttgtcagga tcaaaagctt
    13981 tttccatatc ctcaagaatg taggtcaagg catcaccaat cccctgaatt tcctttccct
    14041 catcatcctt atagtaaata cgagcatcaa taggatcgat aaaaggcagc agaaaaatct
    14101 ggcaattctc caactcaatg ggctcaaaag cctcctccaa acgtgtactt aaatgaaggc
    14161 cctgatgttg aaagaagtca cgcccaaaat gtaaacgttc agccccatcg tgattaccac
    14221 taatcgcata gacaggaatc tgctcctcca gtaccaagcg ggccaaggtc ttattaaaaa
    14281 gcttaatcgc atccacaggg ggcaccgcac ggtcatagag gtccccagaa atgataaccc
    14341 catccacttt ttcgctaata gccaaatcca caatttgttg aaaagcccac tcctgctcct
    14401 ccaacaaaga ccagccattg agggttcgtc ctacatgcca atctgacgta tgtaaaaact
    14461 tcatgacaac ctcctcattc attttgtctt acttctattg taccttatca agctaaatac
    14521 tgcttaaaag tttcacaggc tttgatagtt ttcccgtttt ttagctgtaa agatcaaaaa
    14581 atctctccca agctatcctg tactgacccc aaaaagttag acaatttatg taagcaaagg
    14641 atttagctct gtattgcaca ggattgagtc cttttagttt taccttaatg catttgttgt
    14701 tgtagtaatc aatatagtct agattaccct gcctcaattg gttaagtaat ttaaatacct
    14761 ctaaccaaga aaatcaatat tatctattct tttaattgac ttttatagat tctaagcatt
    14821 atcatatagg ttggtactag tgcacatctt gtattttagg caataatatt tactcacttt
    14881 tcgttattgt cagtaccgat cctttttaaa tttttcacca tgaaaaccta aaaataatcc
    14941 gaaccctaag ggctcctgac tttttacttt attctaggct ttttttatcc gtagcttgtt
    15001 agctgacttg gaactaggca tgtagtattt actatttccc tacttgagat tttttataag
    15061 tcacatgcat tattccatct gaacgaatgg tatgattttt atttctttta gagaaacacc
    15121 ggtaatagct aattcctatc ttaaatcact tgaaatatat ttataatgtg ttggagtgct
    15181 aatcagtacc gcttgtagat ttttggaaga tactaacaca ctaatgattt aatctccttt
    15241 aaaacatgaa aagagaagcc tccaaagctt ctcttttata attatcaaat aatgtacaac
    15301 tagattctta ataactacct aatttagtgg ttcaatcatg aagcttaatt gatagctatc
    15361 tgctgagcta agcaagaatt cgtcatgaac tggagcaccc catgtgtcgt caccacctac
    15421 acccatttga gcagcaagaa ctttaatcca tgtagcatca gattcttgca actcatattg
    15481 gtgacgagca ttttcaattt gttcagtact gttacgcaaa gcactgaatt cgaatgcttt
    15541 attaagtgcg gtgaatttaa gaccattatg gttatcatca gatactgtga attcacgagt
    15601 accatagtga ttaccagatt cttgtggcat tagatatgga gcaaatgtct tttcaacaga
    15661 tgtttcatat cgaccaagat aggcaccagg aagtttatca cggtagcttt cttctgcacc
    15721 gtatccataa tagctaaggt ttgtaaattg tgaaccgata gcaaattcta gaccaaattc
    15781 agggaagttt ggcaaacctg ctttaccatc atagtttgca gtaacaaaga ttcgaccctt
    15841 gtaatcaact tgataagtta ccttaacttc gacatcagac aagcctggca attcatgaac
    15901 ataagtcact ttaacagagt cgtcttcgat ttgaatttga gtatctgtaa ctttactata
    15961 gtttccagca accttccagc ctgccatttc gaatggatat ccagcaccac gatcgttgtc
    16021 agtgtaagca cgagtgaagc taagtttagg acctttctca atgaattcaa caccattata
    16081 cttagcagat actaaagtat tttgtgcacg tgaaagcaag attgagaagt tttgtccttg
    16141 aataccgatg ttgaagtcgc cttcaacaac attcaaaggt gctttaactg gtgtttcagt
    16201 gctaatcttt tcaacaacat attgaccacg aacaatttca tgacctttag gagcccattc
    16261 agttgcttcc ctcagaacac aagcaacttc gtaaatttgt tcagaatttg aagcctcgac
    16321 tacaaagtta actgggaatg ttgcttcttc gcctggttta acatcaaagt gatattcact
    16381 ttcactaact tttctaccat cttcgtaaac tctagctagg aaagtataag cagaaagatc
    16441 ttcgaagaga ttatcattct tgatagttac tgatttttca tcaacagcaa tcttaatatt
    16501 agagtaaaga tgtttaactg tttgaagttt tggagttagg gtacgatctg caaagacgat
    16561 accatttcca caaaattcgt agtcagaagg tctatcatgc cagtcaccac catatgatag
    16621 gaattcgcta ccatttggaa gtgttttgta aatagcttgg tcaatgaagt cccaaataaa
    16681 tccaccttgg tattctggat atttctctaa gtcagtgtag agttgcaatc caccaccaga
    16741 gttacccatt gtgtgcatgt attcacatga aatataaggt ttttgaggtt tgttagttag
    16801 gttacctgaa gcaaagtgtt tatcactaac gcttgaaaga tcaactagtt taccagttgt
    16861 gaggtattct tcgatatcag ctggtttcgc atacatacga ctttcgatgt ctgtaatgta
    16921 atcaaactca cgacaccatg caacaccttc atagtgaact ggacgagtat tgtcaacact
    16981 acggaagtaa tcagccatgt cagcaatatc tttaccagca tatgattcat taccacaaga
    17041 ccaa
//
