LOCUS       gnlProkkaPKNEEJFP_82   15367 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKNEEJFP_82.
ACCESSION   gnlProkkaPKNEEJFP_82
VERSION     gnlProkkaPKNEEJFP_82
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:06:28
            Original ID  :: gnl|Prokka|PKNEEJFP_82
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9702
            Orig. end    :: 25069
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15367
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:14054]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14054
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..15367
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15367
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1228..1494)
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
     CDS             complement(1815..3032)
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             3182..3676
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYHWVQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGAFIKGQNIVPLN
                     T"
     CDS             3682..3870
                     /locus_tag="ctg36_15"
                     /transl_table=11
                     /translation="MIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
     CDS             4061..4402
                     /locus_tag="ctg36_16"
                     /transl_table=11
                     /translation="MVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMSMEVHQKPL
                     NRRKEKPETEAVSQQGMSHKAIASPKKSIPQATQDCLILGDNVPGLSITEEKKSVLASE
                     SIWEMVANG"
     CDS             4882..6072
                     /locus_tag="ctg36_17"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKENQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             6134..6406
                     /locus_tag="ctg36_18"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSIRFNKKSINQWMTRLEISA"
     CDS             6417..7028
                     /locus_tag="ctg36_19"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKL"
     CDS             7320..7634
                     /locus_tag="ctg36_20"
                     /transl_table=11
                     /translation="MRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRHPELAPA
                     SPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIAFRSLKK
                     "
     CDS             complement(7971..8483)
                     /locus_tag="ctg36_21"
                     /transl_table=11
                     /translation="MMFDDRLEIHSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(8712..9977)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 96.3; E-value: 3.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg36_22"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKDSNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVLLYLLVAVAMNFKPSIMIVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSVMNIINQSLGAFLI
                     TFFSFSHLAFINALTFAISLLIMLAIKNQINSYYDETISTSKISQFDFKASFSEITSNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILTPLVVVDLSKDSNLTIINSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTTVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             complement(10001..11224)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308; E-value: 1.6e-93)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_23"
                     /sec_met_domain="LANC_like (E-value: 6.1e-52, bitscore:
                     167.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYGENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             complement(11262..13625)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577.3; E-value: 8.8e-175)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_24"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.5e-65, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.6e-19, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNHVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             complement(13776..14054)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_25"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6e-15, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             complement(14233..14337)
                     /locus_tag="ctg36_26"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             complement(14587..14850)
                     /locus_tag="ctg36_27"
                     /transl_table=11
                     /translation="MAHDFASWVSGDSMEPKYHNGSVALIRETGFDYDGAVYAVVCNSQ
                     TYIKRVYLEAEGLRLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             14994..15167
                     /locus_tag="ctg36_28"
                     /transl_table=11
                     /translation="MNSVRRRHPELSPASPHKLRHTGATLARKSGVPLEIISEALTHSD
                     KQITKTYVNTKI"
     CDS             15230..15346
                     /locus_tag="ctg36_29"
                     /transl_table=11
                     /translation="MNFGVNFINFNKKGSIISVVGKTTVEIIELFECTLKVP"
ORIGIN
        1 cttccttacc ataaggaata atacgaacag ctgttgtttt ctgattaatg acaccaatag
       61 ccgcttcatc ggcaatcatg gccgcaattg ttgtatctgg cgtatcagca ggaatggcaa
      121 tcatgtctag accaacagaa cagatagccg tcatggcttc caatttttca aggttgatat
      181 gcccagattg aactgctgca atcattcctt catcttcaga aactgggata aaggcacctg
      241 acaaaccacc gacctggtta catgccatga taccaccttt tttaacttgg tcattaagaa
      301 gagctagagc cgcagtagta ccatgcgtac caacaacttc aagccccatg gcttcaagta
      361 cacgagctac cgaatcacct actgctggag ttggtgcaag agacaagtct acaataccaa
      421 actcgacacc tagacgttcg ctagccattt gaccaaccaa ctgccctaca cgtgtgattt
      481 taaaggcagt tttcttaact gtttcagcta aaacatcaaa actttcacct gaaaccttct
      541 caacagcacg ttgcacaaca ccaggacctg aaaccccaac attgattaca acgtcagcct
      601 caccaacacc gtggaaggca cctgccataa atggattatc ttcaaccgca ttagcaaaga
      661 caaccaattt acctggaccc attggatctg cctcagaagc ctctttaatg atacgtccca
      721 tatcacgtac cgctgtcatg ttaataccag tttttgttga accaatatta acagatgagc
      781 agacaaaatc agtctcagca agcgcacgtg ggatagaatc aataagaatc tcatcacctt
      841 tttggtagcc cttttgaact aatgcagaga aaccaccaat aaagttaatg ccaatttcct
      901 tagctgcacg gtctagtgcc ctagcaaacg gtacataatc tgtcgcatct gtcgccgcac
      961 cgataattga aatcggagta acagaaacac gtttattaac aattggaata ccaagttcag
     1021 ccgcaatttc gtcaccaaca gctaccaagt tcttagcctt agaaacaatc ttgttgtata
     1081 ccttttctgc tgccttatca atatctgaat cgatacagtc tagaagtgaa attcccatgg
     1141 tgatagtacg aacatcaaag ttctgctcct caatcatagc aatggtttct gtaacctgtt
     1201 taatatccat tttcaactac ccctatctta taagttgtgc atagcatcaa aaatcgctga
     1261 gctttggata ttgattttga cgtttaatga ttcaccaaaa gcttctaatt cagcacgtag
     1321 gtgtgtaaaa tctttcttat cttccgatga tacaaccgcc atcatggtaa agaattcatc
     1381 aaggattgtt tgagtgatat catcaatatt caaaccaagt tctgcgatct tagtcgcaac
     1441 acctgcaaca atacccgctt tatccttacc tacaactgta ataatcgctt tcatgagaag
     1501 cctccatcat tttattttat ataattttag catattttga ttaaaaacgc tattttttat
     1561 agaaattaca ccttttttat tgaaaaaaac gaatgtttct acaacattta accagtatcg
     1621 tttataaaat tcagtctcta tcaattcaac aacttgtgga taaacttgtt aacaagtaaa
     1681 acaatacaat tctaataaaa ccttgaaaaa tcaaggttta acactgagaa cagacttatc
     1741 cacacctgtg gataagtctg ttggtaactt gtcgataaag aaaaatatcg ccaaatttta
     1801 gcgatatctt agctttattt ccattttaga ttaacatgag cattcatttc tttataggca
     1861 gtatctatac gctctttagt ttcttcatct agtttatttc tgtattttcc acctttaatg
     1921 aaatcctcta aaatataggt ttgataagta tataaaggat atccctctgg cgaaattgtt
     1981 cccttgggtg tgcggttaac ccaggttgga tgcgcttgag ctgtcttaat cgtggtttga
     2041 caattctttt tctcaagagt gacatccatt aagacgcccc tctctgtcca tgctgcacta
     2101 tccacaccat ccatagtctc tatgcgctgg ttagagatga aattccccat tgagtaaata
     2161 atgagttttt gctgtccatc ctttttaacc acttcagacg gctcaaccac atgagggtgg
     2221 cccccaaaga taatatcagc accccaatca atcatcttat ggtaaagctt tacctgttca
     2281 tctgtcggtt ccaaacgata ttccacgccc atctgtggca taataaccgt aacgtcagcc
     2341 tctttttcag cacgctcaat ctctactttc atccgttttt catcaagatt cgacaaatga
     2401 ttcgcaatct ctttttcggt cagatttgac tccaagccat tgaaaccata ggcataagaa
     2461 agtattgcca ccttgatgcc attaacattc ttgataaaca gaggcgcctt atcacgcaca
     2521 ggattttcat aaacaccaac agggtcaatg cccacctctt taaatgcatc ggctgttgta
     2581 aaagctccct ctaaaccaga gtccaaaata tgattatggg ccaaatccat aacatcatag
     2641 ccggcatcac taatagctgc cgtcactgat tgaggagcat taaacagagg gtagcctgac
     2701 aaaggataat caggattgat agttccctca aaatcaccca agaccaaatc agcctgcttt
     2761 aaccatggct tcacatatgt aaaattttca gtaaaatcat aactgccatc tgcctgcaag
     2821 gcactcatat agagaccgtc atgataaagc aagtccccat tagccatgat acgtgctgtc
     2881 tgtacttgat ttgaaacact cttttgctgc tcatttttac tatgaataat caaaatttca
     2941 agaaaaagca aacctaagac aagagcaatc aacctcatca aaatcttatt agtcatcgta
     3001 ttgtcatgct ttttagcttg gctctgtttc atcatatctc ctttttcata ctcctagtgt
     3061 aacaaaaaaa tgttatccat agatgataaa aaagattaat aaacggttac atcggttctg
     3121 ttgcaaagtt ttaaatctac tatcaaatca ggtagaataa tagaaaaaga tagcaggagg
     3181 aatgacgata aatcatttta aaggaaagca atttcagcag gatgtgatta ttgtaaccgt
     3241 gggctattat cttcgttata accttagcta tcgtgaagtt caagaaatct tatatgatcg
     3301 tggcattaac gtttctcata cgacgattta tcattgggtg caagaatatg gcaaactact
     3361 ctatcaaatt tggaaaaaga aaaataaaaa atccttttat tcatggaaaa tggatgaaat
     3421 atacatcaaa attaaaggaa aatggcatta tttgtatcga gccatcgatg cagatggttt
     3481 aaccttggat atttggttac gtaaaaaacg ggacacacaa acagcctatg cttttcttga
     3541 gcggttagtt aagcagtttg atgaaccgaa ggttgtagtc acagataaag ccccctctat
     3601 tacaagtgcc tttaagaaac taagagaata cggggctttt atcaagggac agaacattgt
     3661 accattaaat acctgaataa tttgattgaa caagaccatc gtccagtaaa gagacacaat
     3721 aaattctatc gaagtttacg cactgcctct accacgatta aaggcatgga agccatccga
     3781 ggattatata agaaaactcg aaaagaaggc actctcttcg ggttttcggt ctgtactgaa
     3841 atcaaggtat tattgggaat cccagcttaa atcatagata ccgtaaggga ttttattctt
     3901 tatttaaaac tttgcaacag aaccgcattt gactctaatc cagaaaatgc caataatttt
     3961 aacgatgaag tagccgttgt tggactcaca aagcagacca tcattggcaa taaaaatgaa
     4021 accttaaaag tccaagatga caaagcgcaa aaatttgcga gtggttctct caacacgtca
     4081 acagatggtg gcgtctactt caccgatacc tctggctcta ggaaagggcg tgctgaaacc
     4141 atgcaaaaac tcgataccta tatcgatgag catggaggta caccaaaagc ccctgaacag
     4201 acgaaaggaa aaaccagaga cggaggcggt gtcacaacag gggatgtccc acaaggctat
     4261 agcctcacca aagaaatcaa tacctcaagc cacacaggac tgtcttatcc ttggggacaa
     4321 tgtacctggt ttgtctataa ccgaggaaaa gaagtcggtg ttagcttcgg aaagtatatg
     4381 ggaaatggtg gccaatggat gaatgcccca gggtatcaga caactcatac cccaaccgaa
     4441 cactccgctc tatcttttag cccagggcaa gctggagcag atccaactta tggccacatc
     4501 gcctttgtgg aacaagtcaa atcagatggc tccatcctca tctctgaatc aaatatcaaa
     4561 ggactaggag tcgttagcta ccgcactttt gatgcagaaa cagcaaaaca aattacttat
     4621 gtcattggac actgatgatg gttttaataa tattaatttt tagtattatt aatttagata
     4681 cgtttaaaat caatactaaa tgttataatt aatacaaaaa tgactaggtg atctaatgaa
     4741 cgaagttgct aaatcagaaa agcaaaaaga agaatcaatc aaaaaaactt acaatctttt
     4801 gatttattta aaaatgagac agatatcaaa acaacagata tctttgaaat aagtagtcct
     4861 tttgaacaag ctctccccaa catgattaaa gaaagtttcc catttgatat cttaaactta
     4921 tttgatacta aaggaacccc tccattcaac ttttcaaacc aatatcttaa tcctaacact
     4981 aaaatactag atttcaataa tgctactcta tatgaggttg actttgacag tctatctcct
     5041 gacaccaaag cgaaacttca agagggcgct tataaaattg gggaatctag aaaagtagaa
     5101 ggaaatctta gggctgtaat tgtagacaca accgatcaga agaatcgtgt tgaagatttg
     5161 acattaagga aaatgactaa taacaacgaa aatcaagttc ctagtgatct aatcgctcaa
     5221 gctcaactta aacaaatcta taacttactg ttagatatca aagaaaatca agattatcag
     5281 attagatggg aaagaaataa tagtatacta gctccatttt attcagctcg tacaaaagtt
     5341 atagaagcca acaatagcaa agatttcaga gaaaaagtta agtcactaaa ggatgcaaat
     5401 acattatttg aagaatcagt aagtgctatt aaatctgata taatttcaaa tagagatgaa
     5461 attattaaga aaatcagcca accaacatac cgtcaagcct ctttacaaac acatgctgat
     5521 tttttacttc aagacataga aattatgact aaaattgttg gtatgcaaat ttatatcgat
     5581 ttaacactaa ataatgaggg gatagcccat gatcggctac tatcttttca aggttcgatg
     5641 gaattagttt ctaaacaaaa tattccatac aaaacaaatt atttgaaaga actagcaaaa
     5701 aaacttcttt atgtaaaaga attaaaatgg ataaagaata atagtatccc aaaagtaagt
     5761 ttgttagaat taattcataa tcattacagc tactcaaaaa acaataggga cttatttatt
     5821 aatattaata ctaaattaat tgaattccac caagatagta acgttaactt aagcaatacc
     5881 gaaacagcaa aaatcgaaac ggagaaaaaa atgacactaa aaacgaagaa gtgtaaaact
     5941 tgtaaaaaaa caatctcatc acctaaaaca ataccaattt gtgatgcatg tcgtaataag
     6001 ggcaaacaat tgacagtggt cggggtcgct ttgctagttt ttttcaacaa aataataaat
     6061 aagaagaatt aatcttttta acagcaggag agtattttac tcttcttttt tatttttaag
     6121 aggagaataa tatatgctag tacaattgcc agaagaacaa actcaagaaa ttcagcaaat
     6181 gattgcaaca ctaataaaga atgaaattca tcattttaaa gaggatattg gggctgacag
     6241 cacttttcta aacaaaaaac agacttacaa ctacctaggt atctctaata atacacttga
     6301 tattgggatt gcaatgggat taccctatat ccgaatcgga aaatctattc gtttcaacaa
     6361 gaaaagtatc aatcaatgga tgacaagatt agaaatcagc gcataaggag gtaaatatgt
     6421 ctattaagaa aacaaaaaat ggaacatatc aattacgact ttacattcca gaagatgttc
     6481 aagcaaaatt gggtttaggt aaactttttg aaagaaaata taaaaccaga cgagaagcca
     6541 aagaagtaga attaaaactt tctatcgaca ttaaaaatgc taagtctgga aaaagccata
     6601 taaacataaa aaataaagga gaaatcatat tcaaaaaatt ttatgaagat atttggctcg
     6661 aaccatacaa agcaggtcaa accacaacaa caataaaacc acccacaaaa gcaacagttt
     6721 tccaaacaga aaatatattc aggctacaca ttttacccat tctgggtaaa tattctatcg
     6781 aatacccaaa taataataaa caacttattc tttcattact tactcccaaa gcaaatagct
     6841 atgctaattt caaagtaatt aggagctatg ttaattctgt tttcgattgg gctgaggaac
     6901 tagaatatat tccatcaaat aaactccgca aaacaattac tagaattaaa gctaataaaa
     6961 agattctcct taaagaaagc aaacgagagg aagatttatc tctcgataaa gaagagctga
     7021 aattatgatt acaagctttt gacatagact tagagaaagg acttattgat ttaaaagact
     7081 acactctctt ttatacgaca ttctttttat ccgatagaaa atcagaaagt tatgctcttc
     7141 aatggaaaca catcaatttc tctactggag aaacactgat agaacaagct ttagatcgtt
     7201 tcggaaatat aaaacccacc aaaggtcgta agaagaccct ttttaaaaca cctattgaat
     7261 taattgagct attagctaat tggaaagcaa gacaacaaga ggagttaaaa ttatttggat
     7321 tgcgtcaaac tcaaaagcag tttgtattca cctataatga tcgttcaaac aacattaatt
     7381 tacctcttca cgtggattat ctaaattata gaatgaagtc agtcagacgg agacatccag
     7441 aacttgcacc agcatcacca cacaaactaa gacatgcagg tgttactctt gccaaacaag
     7501 caggttattc tcttgaagct atttcagaag ctctaactca tagtgataag caaattacaa
     7561 agacttatgt aaatacaaaa gatatagtta atcggacagt aggcgatatt gcatttcgta
     7621 gcttgaaaaa ataatggtgg aaaattggtg gaaactttgg tggaaactat cgaattttga
     7681 ataaaaaaag acacccaaga gataactctt gaatgtcttg aaacattgat ataatcgtat
     7741 tgattaacgt tttgagaatt gtgaagcttt acgagctttc ttaagatctg gttttaaacc
     7801 aatgaatttc aatataactt aataggtaga aactacaggc aactaggcct tttcttttgt
     7861 ccagaatttc aaaaagtttg agattttttg aggaaaacag gggaaattca cttactgcgt
     7921 tttactccga actactgcac tcttctgcac tccagttata aatagatccg ctattctgcc
     7981 aaagtatagt actgatttct atcttgctta cttgtgccat gccattccag gatctcttta
     8041 tttacaagac tctttaataa tttacttgca aaatttctac ccctatttgt tattctagcg
     8101 gccaaagcag tagtcatttt ctctccggta ttatacatga tatgtaaaat tgctttctca
     8161 tcgtcattta aatcattgaa ttcgtcatat tttttcatca tcttatcatt aactctcaaa
     8221 tgtcggctca aaatattatt ttcaagagtt aaaacaactt tatttcctgg ctctgtgtat
     8281 ttaggttcat gcaagaaata agattccatc tcagaataga ttcgcttcac tccctcattc
     8341 atttctcgta cccatccaaa ttctgttaaa gttctagcaa tacgaggatt acgagaaaaa
     8401 cgttcgtgct taatattttc aaccgttacg atattaggaa gcttacctgg actatgaatt
     8461 tctaatcgat catcaaacat cataattcgg atataatcgc caaaaatgga gcaatttcta
     8521 tgagttaccg catttacatc ccttcaaacc aagcaaattc tggatactct ggtaatgttt
     8581 taaattgccc atcatccaaa tattgaaatt ctctaagctg agtacgaaca aaatctcgaa
     8641 ctttagtact caatcttgaa aataggtttt caatagtaga aaatttggaa aactataatc
     8701 atttaactaa tttaaaattc cctttctatg tgatttgaac tttttaatgt atataaaatt
     8761 gccacaaaaa caactgctat atatattaat gcgatataac catacggtaa gtaaatcact
     8821 aaggtagaaa acaataacct tgacacaata tcccctattt ggaaatatgt caccattcct
     8881 ccaaatattg tagccaactt cgtctcatca atattattaa atatgatagt ccccatttta
     8941 ggatttaatg cactaactaa tacactcgaa agaaatgatg ataatataat taaataaata
     9001 ttttggaagt aaaaagcaac gaatgatagt aaaacagtcg ttaaattcat ttttagcaaa
     9061 gtgcctatgg aaaggctttt aaatttttta ctaattagaa ttaaagtgcc cccaagtatt
     9121 cctcctgaaa cagtgctaat tcctaaaagc gagatcgtaa tcgctgaatt aataattgtc
     9181 aaattagaat ctttagaaag atcaacaaca actaatggcg tgagaattgc caaactccca
     9241 ttaagaattg gtataacaag taaagcttcc ttcatgttgc cgatactaaa tagatggtta
     9301 atcgagagct ttaaatttga agtaatctca gaaaatgaag ctttaaagtc aaattgtgat
     9361 atcttacttg tcgagatcgt ctcgtcataa tagctattaa tttgattttt gattgctaac
     9421 ataattaaca gactaatagc aaaagttaga gcatttataa atgctaagtg agaaaaacta
     9481 aaaaaagtaa ttaaaaacgc acccaatgat tgatttataa tattcatcac agaaacaaca
     9541 gtttgcctaa acgccatagt ttcttctcta tctgactttt tcactattcg attagaaatt
     9601 ggataaaaaa gaccattttc aaattgtccc aatgtatctg caacaagatt aacgagacta
     9661 gcaattatga ctatcataat agaaggttta aaattcatag ccacagcaac caataaatat
     9721 agcagtaccc gtagccataa cgttttaata atcattttca ctttattaag cgttttatct
     9781 gcaatgatac caaaaaatat tgtaaataaa ataggtagag tttccgatat attgacgatt
     9841 gaaatagcta aattactatc cttaatctcc gtaacatagg tcatgagagc tataaagtat
     9901 aatgtatctc caaaatttga tatcaaatcc gaaaccagaa cttttagata tagtttgttt
     9961 tttaagattt ttctcatact tctcctttaa cttaaaaact tcactgcata aacagcattc
    10021 tatccaatgg gtaggcattt ccagtccttt gtgccattag agttataact atccctgaaa
    10081 caccatttag caatccaaag tcaatataat caataacttc atcaaaggtt acgcctctaa
    10141 aatatatgtc acgctccaca aatatatact cagaattaga agcatcattt ataatttctt
    10201 taaataaatt atcagaaatt gctttaaatt gtgtctttcc tgtatctaaa tacatcaaat
    10261 tgaacaaaag cattattcca gaccgtccat gacaaattcc attatttaaa atctcactgc
    10321 tattaaggta atcaatagat gaagtaaata catccatcgc catttctcgt aatttctgac
    10381 tatcaatgat tttcgctata ttatatagta ctcttgccat tccaagactg ccatagcacc
    10441 aacttatatt aaatctaaat tcctcattct ccccataatc actgactcta ccattccaac
    10501 caattatttt tccaattgta ttggtaaaaa aggcgttctc atagtaactc aagccctttt
    10561 ctattgaagg tatgtgtttt gttatattaa atttttcaaa tcctaacgcc aacacgtata
    10621 gtggtcccaa tataccgtga gctacaccta gattaatata gccactagga aatcttttcc
    10681 ttaatttttc atttggcata tattccacat aaatagttgg ctcgttaatt attaggtctg
    10741 caaagtaatt taatatttct tttactaata actcttgttc agaagttgat tcctctttgc
    10801 taagcaaata tctagctaca ctagagacac cttgaattac atcaaagtat tcttctttaa
    10861 caatattaga gctttttatt tcacgtagcc tatcttttgt taaagctaat aaaattgtct
    10921 caagtgtatc tagtaattta tcatatcctt tacaattttt agataaaaat tccaaggcat
    10981 atacatagcc cgtaaatcca tagcaaagtg aaatattatt agtgctattc aatttaatag
    11041 actttagcaa ttcttgtaga taataattta ctctattata gagaagctta gaatactcct
    11101 tattatcaca atttatcaac ctataggata aatatataat tatacttgga tattctgata
    11161 agtaacttct attttctgta taatatgctc tctgcaatct gtcaataata tcactatcca
    11221 acacgagttt atctacttta cagataattt cttcatactt tttaagtaaa ttccttataa
    11281 ttattcaacg gctctgcaat atacatgata aaataaagat attccttttc tctatatgga
    11341 aacatgccta ctctattcat atgcatatga agtaaactat agactatatc atttttacct
    11401 tcaaaatatc catcaatagg cgggaactct ctaaatactt cattaaaaat ttcaaactga
    11461 tttttgtaat caaaatattc tttgaattcc tttactacta ttgtgttatt tgggaataac
    11521 tttttaaaac ttttacgata tctattttga gtcaaattcc ccttcagcaa ctcaagtaat
    11581 cgctttaatg ggatccctaa taatcgaata tataaaaatg tcgaatgcaa aacagaaaat
    11641 aaatctttat catttaataa tttcttcgaa aataacttta gggtaagaaa actgtcaata
    11701 gaaaacatcc tctcacaaac tgttataaag ttatctccac catatctctc aatttccctc
    11761 tcatataaat taaaactaac atcattacaa aaaccacttt ctagtaggaa gtctatccaa
    11821 tgtgcaattc gaaatcttaa atcttcaaaa ttatcatcgt tatttatttt aaatcgtaat
    11881 cgaagcgatc cattatcctt atcgctataa tttacaaaat gaaaatcact aattagcttt
    11941 tcaaccaata gctcgtctgt aaacaaaaga agccgctctc ttagttcaag tagaattgat
    12001 gaattaattc catataatct aaaatagatc caatcactcg aaaatgtttt aacatggttc
    12061 ttataaaagt tatttgtcaa tcttctaaca gatttttcct gcatagaata atgatttata
    12121 ctactttgat aattttcaaa tccaaagata aactcacaat ttttaccatc atatttttca
    12181 aaacgtgtaa aatacagttt atccacattt tgttttaaaa gccactgtgt atctaaatca
    12241 ttctctaaat cgaccaatag acgctcatca gctttatgaa aatacagtag tctaggtaca
    12301 tcaaaatctt ttttccactg tttaatagaa gataaatcat ttttatctat atctgacaaa
    12361 acccacttct cttcacttaa aattatattt ccatatttaa ttttgggaat atagggaaga
    12421 taatcaaaat tttcaattat cctaaacact gaaaacggat tatcttgcca ttctaaagaa
    12481 accgctagca aaaatcttgc taaatcgcta aatactccat ttgatttatg atttagcatt
    12541 gatgttgtta caaaattaac aattgagccg gttcgtaaat ccctaaaata taatttatat
    12601 cgatattctg tttttataac ccccaccacc acagaatcta attcaatcga tgtgttatca
    12661 ttgtcatcat aagataataa taacttttta gaatgagcat tctgtgccga cataacattt
    12721 aaattcttac tatctcttgg aaattctatt aattctacat tatccaactg tgaatctaac
    12781 gagatataag aattaggaaa ataggaggca aaccttccaa tagacttccc tatcatgtca
    12841 ctccctgtat ttgggacaac tgatataaca ggttgagatt caaaattctt aatttcacaa
    12901 tataactcta actgatttgc aacaaatcta tccgaatttg ggtataacaa tcctaaaggt
    12961 atatttgata tatctatctc ttttttacaa tttttaacag ctttgaagac ttctttactc
    13021 agataagaca aaaaattttg ctcttctaca ctacttgatg actttacatg agttcccaaa
    13081 gtttgttttg gtaaacccag tcctaaatta ccatctaata attctttaat tggaacttcg
    13141 acgtattctc catatttttc aacaaatttt tctgtaaatg attctaattc tctgtttcga
    13201 taacctttag ccagattaat ttttgaaata aaattaacaa aatcctccat tttctttttt
    13261 aaatttttgg gcagcaccga atcacaacaa tttactaaat ccaccttcag gtaatgctgt
    13321 tttttatcat taaaaatata cgacattttt ttacaaattt cagtatattg agaaatgcct
    13381 tctcccaact ctaattttgc atactgctca atactatttt ttatttgtaa taaatcctcg
    13441 gttaattttc tttggttatt aatatccttt aaaatgttgg ttaaatcatc taaatcttta
    13501 tggcttattg caacttttcg caagtttgta aacaaaaatt cattagtaat caaattacgt
    13561 atataatcta aaattttctg cttctctaaa tcaggagatt tactttgaag taccagttct
    13621 aacacactga cttccgattt atacgttaat ttttgtatga attctaaaag tccagttttc
    13681 ttgataaata aatccttact tatctcagag attccccagt aattgacatt acttaattga
    13741 tacttatctg ataattcaag tactttttgg ttccactata tatgtagttg taataagaca
    13801 gaatctttat tttctaacat catacaaatc gaacttagcc actctccact aaccgagatt
    13861 tttttcgtat aattttctcc aatcttttga tgatatgaga tatcagaaaa agttcctaca
    13921 ccaattgaac taaacaatcc aaacggcgtt gctcttgtaa ttgatctttt tacatagttt
    13981 ctaaaggtgg aatttttata tattttttct ttagttaaat tatggaaaaa ttgagggttc
    14041 gccactagca acatttcttt aaaaactttg ttatcaaaaa atatttcaag attattttca
    14101 ctaagttttt ctataagtct tgaatcatta acgcattacc tataaatgta attatctttt
    14161 atcttaaaca taattctctt gtaaaaaaag gtaagtacct cgtatacctg ccttattcaa
    14221 tcaattataa aactaatctt tacaacaacc tgtagatgtt acaccaccag aaacataacc
    14281 ttgttctgtt gaaacttcag ttacatcaag ttccaatgaa aattcagtat tttccatgat
    14341 aactctgcct cttctttaag ttgtgtttat aatactaaaa gcaaatttat ttgtcaataa
    14401 tttttagaaa attcattctt tttgtttcgg agtattataa aataaaatcc gtctgtacta
    14461 tcaaacaagc tctgttatca gaagatattt cataagaaat ccttaacaga tgtcattaca
    14521 tttttgaaaa ctagaatcat tatcaaaaaa gcaaacaagt tgacaattca ggactagaaa
    14581 aacgtattat ttgagaggta taaaatttcc aataataatt ctcactactc gtggatcctc
    14641 gtcataagaa ataaagatat ccttatactt tagacgtaga ccctctgctt caagatatac
    14701 tcgcttaatg tatgtttgac tattacatac cacagcatat acggcaccat catagtcaaa
    14761 acctgtttca cgaatgagag caactgaacc attgtgatac tttggctcca tagaatctcc
    14821 agacacccat gaggcaaagt catgcgccaa ctcctccgta aagtaaaccg tttcataata
    14881 aggaattaaa actatttggt ttacaccaga ctcaaaagca gtttgtgttt acctataatg
    14941 accgatccaa taatatcaac cttccacttc atacagatta cctcaactat agaatgaatt
    15001 ctgtcagacg taggcatcca gaactatccc ctgcttcacc acataagtta agacacacag
    15061 gtgccactct tgcaagaaaa tctggcgttc ccctagaaat tatttccgag gcattaactc
    15121 atagtgataa acaaattaca aagacctatg ttaacacaaa aatatagtaa atcaaactgc
    15181 tggagatatt gcatatagaa gcttaaaaaa ataatagggt gaacatgggg tgaattttgg
    15241 ggtgaacttt ataaatttca acaaaaaagg ctctataatt tctgtagtgg gtaaaactac
    15301 tgtagagatt atagagcttt ttgagtgtac actaaaagtc ccataagaac tataatgaaa
    15361 agtgaca
//
