LOCUS       gnlProkkaBKKJCBLI_16   10642 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKKJCBLI_16.
ACCESSION   gnlProkkaBKKJCBLI_16
VERSION     gnlProkkaBKKJCBLI_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 07:49:45
            Original ID  :: gnl|Prokka|BKKJCBLI_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10642
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10642
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2561:6826]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2562..6826
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10642
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10642
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..164
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MVDFQTHIEQKKFSAQQLYNIHFFIEKNSKNAVSKDERFLKHIRS
                     FSTSKNVS"
     CDS             255..779
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             783..1268
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             1265..2548
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVFIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SVLSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             2562..3260
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.4e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             3280..4581
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="CTP_transf_like (E-value: 1.5e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-122, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.5e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             4593..5729
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_7"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.8e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             5726..6826
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 6.2e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg16_8_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_8"
                     /sec_met_domain="Aminotran_5 (E-value: 9.3e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAVLKY"
     aSDomain        5816..6604
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg16_8_Aminotran_5.1"
                     /evalue="6.20E-34"
                     /label="ctg16_8_Aminotran_5.1"
                     /locus_tag="ctg16_8"
                     /protein_end="293"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             6846..8339
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_9"
                     /sec_met_domain="Polysacc_synt (E-value: 4.9e-11, bitscore:
                     32.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDKKNVVKWNFVFYLLEFLYTILVGIILVPLYLKYIPKDLYGFW
                     LATGNILSILTLINPGFSDVIQQKVAYCYGLHDYKKIGLYTVSGICLTFVFSLIVLIIG
                     VVVNLLIGSIFTMQANYLYELKIAFGLMLVGTFLTINYYSFSSILYAFLSSKSIGLIVL
                     LGNSLGTLISIYLIIHGYGLIALGIASVVRGGVFLSCSVGYVIFKFRKKKIKIVFDLNN
                     VKEIFSFSIYNFLGKTGQTLLTNMNSFLTAKFVSPIDAANLRFTQTVPEFGKVLVLRFL
                     YSVAPIIPNLLAAKGLESIRIKLLNIVYFLISFIFLVCIGFYLLNEQFIYLWLGENNFS
                     GKIINFFIIILLFFSSINKVCFQFLFALGDIKKSNKILFYQSLLYLPIAVFTTKFCGII
                     GLLLSGILVELLALFIFFFPKMVDILNISKIDIRKKLFVELTKISFVTVITLLIGSCVK
                     FSNPSWLLFFVEIVFIVLTFFVLLFLCSKTFRNLLSICK"
     CDS             8343..9488
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MKILLVFIDMIRVDHLSLYNDNMEKTSLDLFFENLGGTILTNCYT
                     PAPDTPRSIACLQSGLLPYLNGCDSRVKWPRYFMKPNIETIFDIAVGLGYKVNLCATKS
                     DIETGLFKFKENENISIFTTIEDFTDTVHLSENTLSLIAIDDYHSAIDDYGGTSLGIKE
                     GQKVILYSLNNFLTPDIVNKYDYSFFFSDHGHALQSEIVMQKNKLELLSDGRTKLFMFY
                     HNINNKKIVKDSRLASILDLYASIVDLIGSGDFRQGFSFFRDSQRDILHIEDHADFRVS
                     PEQIVSQWRVISDEIDIRTNVFETLNKKGQIIDINVVKKYLDSFSPSFSYYMKQIEILK
                     MYEKMKQRKTHYFNGVKRANWWIRCYVRIINRLYILINRLK"
     CDS             9485..10354
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MIVSSLRGGLGNQMFIYAMVKAMALRNNVPFAFNLTTDFANDEVY
                     KRKLLLSYFALDLPENKKLTFDFSYGNYYRRLSRNLGCHILHPSYRYICEERPPHFESR
                     LISSKITNAFLEGYWQSEKYFLDYKQEIKEDFVIQKKLEYTSYLELEEIKLLDKNAIMI
                     GVRRYQESDVAPGGVLEDDYYKCAMDIMASKVTSPVFFCFSQDLEWVEKHLAGKYPVRL
                     ISKKEDDSGTIDDMFLMMHFRNYIISNSSFYWWGAWLSKYDDKLVIAPGNFINKDSVPE
                     SWFKLNVR"
     CDS             10362..10640
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="MNVLVTGAAGFIGSHVCKRLLQRGDEVVGLDNINSYYDINLKYGR
                     LSSLGVPQSELSWYKFTRSNVYPRFSFVRMNLEDRQAMQMLFANGNFD"
ORIGIN
        1 atattgttga ttttcaaaca catatagagc aaaaaaagtt ctctgctcag caactttaca
       61 atattcattt tttcatcgaa aaaaactcaa aaaatgctgt ttcaaaagac gaacgttttt
      121 tgaaacacat tcgttcgttc tcaacttcta aaaatgtttc gtaaaatttg acggtttgaa
      181 agagaaaaga tgtctcgttc aaaccgcgaa gcgcacccga aacaaaggaa aatttcccca
      241 agtataaatc gtaaatgtct gaacaacaga agtattggtt tgccgcccgt acccgagata
      301 aacaagagtt tgctattcgt gactctcttg aaaaattgaa gactgaactt gatctcaatt
      361 actatcttcc cactcagttt gtcatccggc agttgaaata tcgtcgaaaa cgggtggaag
      421 tccctgttat taagaatctt atcttcatcc aagctaccaa gcaagatgct tgtgatattt
      481 ctaataaata caatatccag cttttttata tgaaagacct gcttaccagg gctatgctga
      541 tagttcctga taaacagatg caggacttca tatttgtcat ggatttagat ccgaatggcg
      601 tcagtttcga taatgaccat ttatctgtcg gtagcagggt tcaggtagtt aaaggtgatt
      661 tctgtggtgt cgagggcgaa cttgccagcg aggccaacaa aacttatgtt gttattcgta
      721 ttgccggtgt attgagcgcc agcgtcaaag ttcctaaaag ttatttacgt gtcatttaag
      781 ttatgaatac actcacttct caaattgaac aattacagag tctcgcgcac gagttactct
      841 atttaggtgt ggatggtgct cctatttata ccgatcattt ccgtcagttg aacaaagaag
      901 ttttagaaca atccgatgcg ttgtatcctc agcgtggtgc tactcccgaa gaggaagcaa
      961 acatctgtct ggcattattg atgggttaca atgcaaccat ctataatcag ggtgacaagg
     1021 aggagaaaaa gcaagttgtt ctcaatcgtt gttgggacgt gcttgaccaa cttcctgcta
     1081 ctttattgaa atgccagtta ttgacttatt gttatggtga ggtgtttgaa gaggagttgg
     1141 cgaaagaggc gcatactatc atagaaagtt ggagcaatcg agaactttta aaagctgaaa
     1201 aagaaatagc tgaaagtttg aataatttgg aagctaatcc atatccgtac agcgaactac
     1261 acgaatgatt cgttcctttc tttcccgttc tcccctttac gttttggctc tctatgccag
     1321 cgttttgatt tttctggttt atacttgtgc ctatgcctac cgtaagccat ttaccgcagc
     1381 catttatgaa ggtgagattc tttggggatt cgatgtcaaa attctgtatg tcctttctga
     1441 gattatcggc tacgcccttt ccaagttcat cggtgttcgt attttgcctt cgatgaaagc
     1501 gggtcaccgc atctattata taatagggct gcttactttt tccgaagttg ctttgttggg
     1561 ttttgcactt cttccggttc ctttgaaggt gtgttctatt tttctgagcg gtcttcccct
     1621 gggtatgatc tggggtgtca tttttagcta tatcgaaggg cgtcgtatca gtgaaatatt
     1681 gaatgtcggg ctgagcgttg ctttgatagt ctcttccggt ttggtgaaaa ccttgggaca
     1741 attcgtgatg gataatttgc atgtgtcgga atattggatg ccttttacca caggtttgtt
     1801 ggtataccct gttatgttgc tttgcagctg gcttctcaat cagattccgg ctcccaatga
     1861 gcaagatatc atacagcgta ccaaacgtgc tccgatggat ggtaaagaca ggcgtaaatt
     1921 tttgaggcaa ttcttctggg gaatctgcat gctggttgtt ttttacggtg ccctgaccgt
     1981 gttccgtgag cttcgtgact ctttcgctgc cgatatttgg aaggagctcc atattgaggg
     2041 tgcaatgatc tttactcaga cagaggttcc cattgccgtt tttgtccttg tactgatgtt
     2101 cctgattgtg tttgtccgta ataaccgttt ggctcttaat atcatttatt gcattgccgt
     2161 cacaggcggt tccttaatgg ttttttccac attgctttat gtgtacggtt ttctttctcc
     2221 tatttggtgg atgattcttt ccggtcttgg tctgtatatg gggtatattc ctttcactta
     2281 cctgatagaa cgtctgattg cttcccttag ggtggttagt acggctgttt ttattattta
     2341 tttggccgat tctttcggct atctgggcac tacgggtgtg tttatggtca agaacttcgt
     2401 ttctgctgac atttcctgga ctgtcatgct aatgcgtact gccctttttt caggatttgt
     2461 ttctgtcctg tcgatttttg cgatttactg ttatttcaag caacaattga attcacttat
     2521 attaattccc tctgaaattc atgattaaaa cagcaatgat catggctgcc ggtcttggta
     2581 cccgcttcgg gcattatacc gagcttgtgc ccaaaggttt tgtggaggtt ggtggaaaac
     2641 ctatgattat ccgctctatc gaaacccttc tttcctgcgg tatcgaacgt atcatcctcg
     2701 gtacgggtta taaaaaagag gcttatgaag cccttcaggc ggatttcccc cagatagaga
     2761 cctgtttcag tccccgttat gccgatacta acagtatgta cactctgtac aatacgcgtg
     2821 acgtgatagg cgatgacagt ttcctgctgc ttgaatcgga ccttgttttt gaacgcaagg
     2881 ccatcctttc gctgctggat gacgaattcc cggatgtgat gcttgtctct tctctgacca
     2941 agttccagga tcagtattat gtggaatatg accgcaatca catccttact tcctgttcgg
     3001 tagacaagaa cgcccttgag gcaaaaggcg agctggtcgg tatccataaa ctttccaata
     3061 ctttctaccg ccggatgtgc gccgattatg cgaccatcct ggagtcccag cctaaactgg
     3121 gttacgaata cgaactgctc cgcatgtccc gttccgtttc ccctgtccgt gtgctcaggg
     3181 tggagggtct taaatggtat gaaatcgatg atgaagccga cctttcgtat gccgaggagc
     3241 acatcatccg ctattgttaa aaacaaatct tttccatata tgaacaagaa aatttatgtc
     3301 ggtatgaccg cggatatcat gcatccgggg ctgatccata ttattcatga agctactaaa
     3361 tacggtgatg tcatcgtcgg tctgctgacg gacaaggcca tcgccgaaca caaacgcctc
     3421 ccttacctta cctatgatca gcgtaaggag gttgttgaga atatcaaggg ggtttttgag
     3481 gttgttcccc aggaggactg gagctatgtt ccgaatctgg aaaaactcaa gcctgactat
     3541 atcatccacg gcgacgactg gaaaacgggc ccgttgcgcg aggtgcgcga acaggttttt
     3601 gaggtgatga acgcccaggg gggcaaggta atcgagatcc cttatacccg gggcatcaac
     3661 tcctcctcgc tcgacaagga tatcaaggcg atcgggacta cccctgacgt acgtcttaag
     3721 tccctccgcc gcctgatcca ggccaagcct gtggtccgta tcctggaggc tcacgacggt
     3781 ctttgcggtc tgattattga gaatcttgaa gtccagaagg gggataagcg cgaggtcttt
     3841 gacggcatgt ggtccagcag cctgaccgac tccacgagta agggtaaacc ggatattgaa
     3901 gcggtcgacc ttaccacccg tttacaggac ctgaacaata tccttgaatg taccaccaag
     3961 cctattattt ttgatggaga cacgggtggc aagatcgaac actttgtctt tactgtgcgc
     4021 actctggaac gtcatggcat ttctgcagta atcattgaag ataaagtcgg tctgaagaag
     4081 aattcccttt ttggtactga cgctatccag actcaggata gtatcgaggg tttctgcgat
     4141 aagatcagag cagggaagaa tgcccaggtc accggtgact ttatgatcat tgcgcgtatc
     4201 gaaagcctta ttgccggcaa acccatgagt gacgccctcg aacgtgctta tgcctatgta
     4261 caggcgggtg cggacggcat catgatccac agcaaggata agtcgggtga ggatatccgt
     4321 gagttctgcc ggactttccg caaagaatac gcccatgttc ccattgtcgt tgttccgacg
     4381 acttatgacc atgtgcacga atccgaactt cacgaatggg gtgccaacgt agtcatttac
     4441 gccaaccacc ttctccgtgc cgcttacccg gccatgatga acgtggccag gaccatcctt
     4501 gaaaacgagc gcgccgagga ggtccgtccg ctttgtatgc ctatcaagga aattctggaa
     4561 ttgattccgg gcactaaata aatcagacgg ttatggtaag tgtagaaaag atatacgata
     4621 cgttccttca tcacggtgtt gacttcttta cgggtgttcc cgattccctt ttgaagaata
     4681 tttgcgccta tatcacggat catgctccgc gtggtaagca tatcatcgcc gccaatgaag
     4741 gttccgcggt gggcattgcc tgcggttatt atatggcttc tggcaacgtt cctttggttt
     4801 atatgcagaa ctccggtctg ggaaatacgg tgaatcccct cttgtccctt gcggacgaga
     4861 aagtgtacag ccttcctctt cttttgctgg tcggctggcg cggtgagccc ggcacaaaag
     4921 acgaacccca gcataagaag cagggcgagg ttacccttga tcttctgaaa gccatgaaaa
     4981 ttccttttat aattctggat acggatgaag acgaggccct ggcgcagatc catgacgcgg
     5041 ttgtctcggc gaagagccgg tcgattcccc atgcgattgt catccgtaaa gatacgtttg
     5101 gaaaatataa attgcgtcag gaagccttga atgactatcc tctgtcccgc gaggaggcgc
     5161 taatgcaggt tgtcgaccac ctcggggaca atgacattgt ggtttccacc acgggcaagc
     5221 tctcccgtga gcttttcgag taccgtgaat cgaaagggca ggggcacgca agggatttcc
     5281 taactgtggg ttccatgggt cacagttctt ccattgccct ggggattgcc cttgagaagc
     5341 ctgaccgccg tgtctactgt cttgacggtg acggtgcctt tatcatgcac atgggtgctg
     5401 tcagcaatat cggcgatctt tctcccaaga attacaggca cgtccttttc aacaacggtg
     5461 cgcatgaatc tgtcggcggt caacccacgc tcggtttccg tctggatatc gcctcgatag
     5521 cgaaaggttg cggttatgcg catgtactga ctgcctccga caaggaaggg ctttcgtgtg
     5581 cgcttgagaa gctgtccggc ctgtccggcc cggttcttct tgaaattaag gtccggatcg
     5641 attcacgtga tgatctgggt cgccctacga ctactccggt agagaataaa gagcatttta
     5701 tggcattttt aaaagatacg cattcatgaa tatcgaaaga aagatccttt tgaatccggg
     5761 tcccgccacc acgacggata cggtaaagct ggcgcaggtt gttcccgata tctgtccgcg
     5821 tgagaaagag tttgcgggta tgatgaaaca gttacgtgac gacctggtcc gcgttgcgca
     5881 tggagacctc tccaaacata cggccgtcct gttttgcggc tcgggtacga tcaatatcga
     5941 tatctgcctg aactctcttc ttcctgcgga taagaaagtt ctggttgtca ataacggtgc
     6001 ctatagcacc cgtgcggtgg aagtctgcga atattacggt cttccccata tcgatttgaa
     6061 gttttccgtt tacgaacttc ccgacctgtc ggtaatcgaa aagacgcttt ccgacaatcc
     6121 ggacatcgct ttggtctata ccacgcacca tgaaacgggt acgggtatct tgaaccccat
     6181 ccgtgagatc ggaaaaatag cccattcgca cggtgccgtt tttgttgtcg acaccacttc
     6241 ctccctgggt atgattcctt ttgatatcgg gaaggataat gttgactttt gtatggcttc
     6301 ggctcagaaa ggccttcagg ccatgacggg tctttccttt atcataggtg atgaatccct
     6361 gatacgtgct tcaagggatt atccgaaacg ctcctactat tgtaacctct atttacaata
     6421 cgattacttt gagaagacgg gtgagatgca ttttactcct cctgttcaaa ccgtttacgc
     6481 tgcccgtcag gctcttgatg aatattttgc agtaggtgaa gaggctaaat tcgcccgtca
     6541 caagagggtc tttgaagcca tccataaagg tttgcaagag cttggtcttc agtatgcgat
     6601 caaacgtgaa tggcagtcgg gtcttgttgt ttctgtattg tatcctgatg atcccctctg
     6661 ggattttgat aaggttcatg attactgcta tgaacgtggc tttacgatct acccgggtaa
     6721 gatttccaca acgaatacat tccggctttg tgcgttggga gagattgatg tggaggatat
     6781 tgagaggttc tttgaggtga tgagggaggc tgttttaaaa tactagagaa attgtcaatt
     6841 gggatatgaa agataaaaaa aatgtagtaa aatggaattt tgtattttat ctcttggaat
     6901 ttttgtatac aattttagtt gggattattt tggttccgtt gtatttgaaa tatattccaa
     6961 aggatttata tggtttctgg ctagctactg gtaatatatt gtctatttta actcttatca
     7021 atcctgggtt ttcagatgtg atacaacaaa aagttgcata ttgttatgga ttacatgatt
     7081 ataaaaaaat aggattatat accgtttcag gtatttgtct tacgtttgtt ttttcattaa
     7141 ttgttttgat aatcggagta gtagttaacc ttttaatagg tagtatattt acaatgcaag
     7201 ctaattattt atatgaatta aaaatagctt ttggcttaat gcttgttggt acatttttaa
     7261 ctattaatta ttattccttt tcttctatat tatatgcttt tcttagtagt aagtcaatcg
     7321 ggctaattgt acttctaggc aatagtttag gtactttaat atctatttat cttattatcc
     7381 atggatatgg tctaatagct ttgggaattg catcagttgt tcgaggaggt gtttttttgt
     7441 catgtagtgt tggctatgta atatttaaat ttcgaaaaaa gaaaataaaa attgtatttg
     7501 atttaaataa tgttaaggag atcttttctt tttctatata taatttttta ggtaaaacag
     7561 gacaaacatt gttgactaat atgaattctt tcttgactgc taagtttgtt tctcctattg
     7621 acgctgcaaa tttgagattt actcaaactg tgccggaatt tggtaaagtt ttagttttaa
     7681 gatttttata ttctgttgct cctattattc ctaatttgtt agcagctaag gggttggagt
     7741 ctattagaat aaagcttttg aatattgtgt attttttgat ttcctttatt ttcttagtat
     7801 gtattggttt ttatctattg aatgaacaat ttatatattt atggcttggt gagaacaatt
     7861 tttcagggaa aataattaat ttttttatca ttattttatt gtttttttct tctataaaca
     7921 aggtctgttt tcagtttctt tttgcattag gagatataaa gaaaagcaat aagattttat
     7981 tttaccaatc tttgttgtat ttacctattg ctgtttttac aacgaaattt tgtggaataa
     8041 ttggtttatt gttatctgga atattagtag aattattggc actattcatt ttcttctttc
     8101 ctaaaatggt tgatattctt aatatttcga aaatagatat tagaaagaaa ctttttgtgg
     8161 agttaaccaa aatatctttt gttacggtta ttacattatt aataggttct tgtgtcaagt
     8221 tctctaatcc tagttggcta cttttctttg tggaaattgt ttttattgta ttaacatttt
     8281 ttgttttgtt gtttttatgt tcaaagactt ttcgtaattt attgtctatt tgtaaataaa
     8341 agatgaagat actactagtt tttatagata tgatacgtgt tgatcattta tcattatata
     8401 atgataacat ggagaaaaca tcgttggatt tgttttttga aaatttagga ggtacaattc
     8461 taactaactg ttatacacct gcacctgata ctccaagaag tatagcttgt ttgcaaagtg
     8521 gcctattacc ctatttgaat ggctgcgata gtcgtgtcaa atggccaaga tattttatga
     8581 aacctaatat agaaactatt tttgatattg cagtagggtt aggatataaa gtaaatttgt
     8641 gtgcgactaa atctgatatt gaaacagggt tgtttaagtt taaagaaaat gaaaatatta
     8701 gtatatttac tactattgaa gattttactg atactgttca tttgtcagaa aatacattgt
     8761 ccttaattgc cattgatgat tatcattctg ccattgatga ttatggagga acctcattgg
     8821 gaattaaaga agggcagaaa gtgatattat attctttaaa taattttcta actccagata
     8881 tcgtaaataa atacgactat tcgtttttct tttcagacca tgggcatgct ttgcagagtg
     8941 aaattgtcat gcaaaaaaat aaactagaac tacttagtga tggaagaact aaacttttta
     9001 tgttctatca taatattaat aataagaaaa tagtaaaaga ttctaggctt gcttctattt
     9061 tggatcttta tgcctctatt gttgatttga ttggtagtgg agattttagg caaggttttt
     9121 ccttttttag agacagtcaa agagatatac ttcatataga ggaccatgct gattttaggg
     9181 tgtctccaga gcaaattgtg agtcaatggc gagtaatttc agatgaaata gatattagga
     9241 ctaatgtatt tgaaacttta aataaaaaag gacaaataat cgatataaat gtggtaaaaa
     9301 aatatttaga tagtttttcc ccctcgtttt cttattatat gaaacagata gagattctaa
     9361 aaatgtatga gaaaatgaaa caacggaaaa cgcattattt taatggggta aagcgagcta
     9421 attggtggat ccgctgttat gttagaatta taaataggtt atatatacta ataaatagat
     9481 tgaaatgatt gtatcatctt tgcgaggagg attggggaat caaatgttta tttacgctat
     9541 ggtgaaggcc atggcattaa gaaacaatgt accattcgct tttaatttga ctactgattt
     9601 tgcaaatgat gaagtttata aaaggaaact tttattatca tattttgcat tagacttgcc
     9661 tgaaaataaa aaattaacat ttgatttttc atatgggaat tattatagaa ggctaagtcg
     9721 taatttaggt tgtcatatac ttcatccatc atatcgttat atttgcgaag agcgccctcc
     9781 ccactttgaa tcaaggttaa ttagttctaa gattacaaat gcttttctgg aaggatattg
     9841 gcagtcagaa aaatattttc ttgattataa acaagagata aaagaggact ttgtaataca
     9901 aaaaaaatta gaatacacat cgtatttgga attggaagaa ataaaattgc tagataagaa
     9961 tgccataatg attggggtta gacggtatca ggaaagtgat gtagctcctg gtggagtgtt
    10021 agaagatgat tactataaat gtgctatgga tattatggca tcaaaagtta cttctcctgt
    10081 tttcttttgt ttttcacaag atttagaatg ggttgaaaaa catctagcgg gaaaatatcc
    10141 tgttcgtttg ataagtaaaa aggaggatga tagtggtact atagatgata tgtttctaat
    10201 gatgcatttt cgtaattata taatatcgaa tagctctttt tactggtggg gagcatggct
    10261 ttcgaaatat gatgataagc tggtgattgc tccaggtaat tttataaata aggattctgt
    10321 accagaatct tggtttaaat tgaatgtaag ataaaatctt aatgaatgta ttagtaaccg
    10381 gtgctgccgg atttataggt tcgcatgttt gtaagcgtct tttgcaacgt ggggatgaag
    10441 ttgtgggctt ggataatatt aattcgtatt atgatattaa tttaaagtat ggacgccttt
    10501 cgagcttagg tgttcctcaa tctgaactgt catggtataa gttcacacgg agtaatgttt
    10561 atcctcgatt tagttttgtg cggatgaacc tcgaggatag gcaggctatg caaatgctgt
    10621 ttgctaatgg aaattttgat gt
//
