LOCUS       c00022_gnlPro..        25412 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJJPBCEJ_31.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 14:17:46
            Original ID  :: gnl|Prokka|AJJPBCEJ_31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 16206
            Orig. end    :: 41618
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25412
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[26206:31618]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15412
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25412
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25412
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             complement(138..503)
                     /locus_tag="ctg22_15"
                     /transl_table=11
                     /translation="MHSEMLLHSVKADLHEKQEQIHQLKRVLHEIRQIKHEFSEAQHLI
                     HRPHLNREAWRGTHAHRFEDIREGMNKAYQQIKSDQVSGIIESIEGKIHSLEGDVYSIR
                     RQITKIEHEIEKEKHKK"
     CDS             812..3946
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_16"
                     /sec_met_domain="PLDc_2 (E-value: 5.3e-17, bitscore: 55.6,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNSGFHEELQEKHQLYPVEHRFQPVLPKEYPEILTLHIAKQFG
                     EKIKTLVHHGQYNQAVELTQKISSDLGNDTAFSIPLSSVLYHVGDLDLPVSEHFSLSRL
                     NLLGNHRADDNFFKALKNEMLTADRVDFMVSFTRWSGVQLLIPPLQELNKRNVPVRIIT
                     STYMGITEPKALKQLMQFQNVDLRIVNDYSQSFHTKAYLFERLSGQHSVIIGSSNLSQS
                     ALTTGYELNARIPDTKYLPIFQQTKDVFNKIWVEKTQPVDDQFLKAYEEFQVANHKMSA
                     SRVSQNSLYQTKIQPNAMQEIALKNLKKTREQGEERAVIIAATGTGKTYLAAFDFSEYQ
                     PKKYLFIAHREELLTKAIETFEKVTNDHDNFGLLTGSKKEWNKRFLFSTVQTLYKEETL
                     KRFAPDEFDYIVIDEFHHAEASTYQSVLNYFKPGFLLGLTATPERLDGKDVLEICNHNV
                     VYEIRLRDALEAELLAPFHYFGIPDHTVDYDKVKITNGVYDERSLVNHLKNHERVDYVI
                     KMINMYGFDGERMCGLGFCTNVEHAQYMSKEFNQLGFHTTYLTGQDSSAQRQKVIRELE
                     DPHHSLELIFTVDIFNEGIDIPKLNLLLFLRPTESPTIFIQQLGRGLRKTDDKEFVTVL
                     DFIGNYQKSFVIPLALSGQTSQKSFDKDSLRVAVTHEFADLPGGSYVDLASVTKKEILH
                     KIDSIKLNSATMLKTLYYQFKRDIGRSPELLDFLYSDQAPGLTFFIKKYKSWVETKRKM
                     DDLHSLDKEVLNDSLVLRMVSWLEQQFPIKWPYDLLLLQCGFNIQRITIDDVKKSLEDT
                     FHLKIKNTNIHDNLIKRSMERLSTPHKKQQWSFGTVEENTFILQLNIFERLCHPRFGPY
                     IKERIQYGLTEFRRMNNLEALLSSELQLTLYQTYTRNELIHLFQSTDQEGTWREGVRRV
                     NNNYLIFITLNKSEQVEDHLLYKDYFIDPYHFHWQSQNQTSHASTVGQNLINHRQREYK
                     IHLFVRKFNEMHDITLPFIYLGKVDYVSSNGDKPMNVIWKLHQPVPENLYVDLIN"
     CDS             complement(3935..4324)
                     /locus_tag="ctg22_17"
                     /transl_table=11
                     /translation="MKKTIKVAAAVIQNDKNMILCALRSPTMSLANLWEFPGGKLEEGE
                     NAREALVREIYEELGCKIEAGEIIADIHHEYEKIIVNLISIQAKIIEGEPVAKEHAELR
                     WVPVSELESLEWAPADIPTVNVLVN"
     CDS             complement(4529..6853)
                     /locus_tag="ctg22_18"
                     /transl_table=11
                     /translation="MPLRIESALYAYFSKESRLHKDSETLLFPFGLNLSQIQAVQSAFS
                     SQISVIEGPPGTGKTQTILNLITNIVMKGKNAAIVSSNNAAVANVREKMEKAGYDFLLA
                     SLGSQDNQKKFFEQLPELPQNIAEWKIENERESELLKSVFSDVGSIKELLKLKNRQAVI
                     KQQIKDLETEKKYYKQHFESLETMKPKLLPFYKFNNYKILNFMADEVLNKQNRMNFFKK
                     TKYLFYYGLYDFKQIGDSLNKEKMLSQLQYQFYKQKLTELNSELNKINQILLDKNFDEL
                     SNRIQNYSTLIFENYIHNKQKTVKKENFEYKKYKDAKQFDRFINRYPIILSTAFSLMKS
                     IPDGFLFDYLIIDEASQLELMPGILALGCSKNVIIVGDTKQLPHIPDKNISKGEMGIEP
                     CFDYVENSLLHSVLKVYENKIPVTLLKEHYRCHPMIIKFCNEQYYDGNLIPLTKYDEVD
                     DSSIILIKTVKGNHMRFQGGRHNVRELDSLEEAMIRDKVFPHDFDDIGFIAPYRAQIKA
                     ANRYMREEIIKDTVHKFQGRECDGIIFSTVLDDKGGKKDIEFVDSATLINVAVSRAKKR
                     FVLVSAVDIFKRSNKEISELIRYMEYYTEASLYHESQVISVFDLLYKEFSEVLVQRENK
                     LRESDSKYKSERIIASLLRDILKEEAYKKIEFRREYRLKDLFNDTSHLNQEEQKFIKTV
                     ARFDFLLYYKMGNEPAGVIEVDGTAYHNSNDQKRRDELKDSILRKSGIPFIRLRTNESG
                     EAEKIKGLLNSILKTNKLKND"
     CDS             complement(6888..7286)
                     /locus_tag="ctg22_19"
                     /transl_table=11
                     /translation="LTGVSIEVGNTTYSDQIKEWQLSKRDNAKIIVHFTLNNGMKKSEE
                     LDRCIITPVRKLVINKQERLVLKGNVKANIDSVKIYGEKYAVLTFSGNDRKYIYKEKDI
                     EKITLGNAKFKQLLDYFRHVAAVKDKTK"
     CDS             complement(7441..8859)
                     /locus_tag="ctg22_20"
                     /transl_table=11
                     /translation="MFNRLFRVCFLAALIMAFTLPNSVYAQKPVFKEVSVHDPSIIETN
                     GTFYVFGSHLASAKTNDLMQWQQLTTSVSNDNPLIPNVYKELKETFEWAQSDTLWAADV
                     TQLADGKYYMYYNACRGDSPRSAMGVAVADNIEGPYKNKGIFLKSGMEGTSSDGTPYDA
                     TKHPNVVDPHTFFDKDGKLWMVYGSYSGGIFILEMNPKTGFPLPGQGYGKKLLGGNHSR
                     IEGPYVLYNPDTQYYYLYLSYGGLDATGGYNIRVARSKKPDGPYYDAEGNPMLDVRGKE
                     GTFFDDRSIEPYGVKLMGSYTFETENEKGTGYVSPGHNSAYYDEKTGRSYLIFHTRFPG
                     RGEEHEVRVHQLFMNKDGWPVTAPYRYAGETLKEVKQKDITGTYKLIKHGKDISADIKK
                     TINIQLNKNHSISGEMTGTWKKTGKNTADITLAGKKYNGVFLRQWDSVREKNVMTFSVL
                     NGSGEAVWGSKLKG"
     CDS             complement(8931..9038)
                     /locus_tag="ctg22_21"
                     /transl_table=11
                     /translation="MQAAVPRKTDRHQSDYVREQWGITYPFEYENIRPS"
     CDS             9433..9888
                     /locus_tag="ctg22_22"
                     /transl_table=11
                     /translation="VIHMTLHKERRIGRLSVLLLLNEAEESTQVEELERDGWKVCLGKV
                     GSMDAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVG
                     LRFAVLRGNPYESEAEGDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             10001..11527
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_23"
                     /sec_met_domain="Lyase_aromatic (E-value: 3.7e-198,
                     bitscore: 652.4, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADVARVLFDFEKTAASEESMERVKKSRAAVERIV
                     RDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRAN
                     ALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFF
                     EGERMPAMTGLKKAGIQPISLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIAS
                     LTIEGLRGIIDAFDEDIHSARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRC
                     IPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKI
                     AISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYT
                     KQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI"
     CDS             11524..13182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_24"
                     /sec_met_domain="Urocanase (E-value: 4.5e-92, bitscore:
                     301.0, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 1.4e-96, bitscore:
                     315.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 3.5e-63, bitscore:
                     204.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVKKSIRANRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARDWDAFHAIEHSLKTLKNDETLLVQSGKPVGMFRTHPQAPRVLLANSVL
                     VPKWADWEHFHELEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TLTLTAGLGGMGGAQPLSVTMNEGVVIAVEVDEKRIDKRIETKYCDRKTASIEEALAWA
                     EEAKRAGKPLSIALLGNAAEVHHTLLNRGVKIDIVTDQTSAHDPLIGYVPEGYSLDEAD
                     RLRQDNPELYVRLAKQSMKKHVEAMLAFQQKGSIVFDYGNNIRQVAKDEGLENAFDFPG
                     FVPAYIRPLFCEGKGPFRWAALSGDPADIYRTDALLKELFPTNKALHRWIDMAQEKVTF
                     QGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTAAGASWVSFHHGGGVGMGYSLHAGMVAVADGSELADERLARV
                     LTSDPGMGIIRHADAGYERAVEVAKEQDIIVPMQK"
     CDS             13195..14460
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_25"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-20, bitscore:
                     67.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILINIGQLLTMESSGPRAGKSMQDLHVIEDAVVGIHEQ
                     KIVFAGQKGAEAGYEADETIDCSGRLVTPGLVDPHTHLVFGGSREKEMNLKLQGISYLD
                     ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTTTAEVKSGYGLEKETELKQL
                     RVAKKLHESQPVDLVSTFMGAHAIPPEYQNDPDQFLDQMLSLLPEIKEQELASFADIFT
                     ETGVFTVSQSRRYLQKAAEAGFGLKIHADEIDPLGGAELAGELKAVSADHLVGASDEGI
                     KKLAEAGTIAVLLPGTTFYLGKSTYAKARAMIDEGVCVSLATDFNPGSSPTENIQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQLKVGRSADLVIWQASNYMYIPYHYGV
                     NHVHQVMKNGTIVVNREGAILG"
     CDS             14453..15412
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_26"
                     /sec_met_domain="Arginase (E-value: 4.7e-68, bitscore:
                     223.3, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDKYPFLREAGSSFKDRDVTKMSDLIATWDGQDIKGPALIGVPLS
                     KSSISHSGASFAPGTIRQALKHSSAYSAELGEHVVSELLYDLGDIDIHVTDIVKSHHHI
                     FQTMHALLSDHPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDGGP
                     TNGTPFRRLLDEEIIKGQHLIQLGIREFSNSQAYEAYAKKHNVNIHTMDMIREKGLIST
                     IKEVLPAVQNRTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVA
                     GIEIVEVDPTIDFRDMTSRAAAHVLLHALKGMKLSPFK"
     CDS             15550..16914
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_27"
                     /sec_met_domain="AA_permease (E-value: 5.1e-136, bitscore:
                     447.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISLGGVIGTGLFLSTGYTLHQAGPGGTILAYVIGGLMMYLVMQC
                     LGELSVAMPVTGSFQKYATTFIGPSTGFMVGIMYWINWVVTVGSEFTASGILMQRWFPD
                     SSVWMWSAVFAALLFICNAFSVKLFAETEFWFSSVKIVTIILFIILGGAAMFGLISLNG
                     TADAPMLSNFTDHGGLFPNGFLAVFIAMISVSFAFSGTELIGVTAGESANPQKDIPRSI
                     RNVAWRTVIFFIGAVFILSGLISWKDAGVIESPFVAVFAEIGIPYAADIMNFVILTALL
                     SVANSGLYASTRMMWSLANENMISSRFKKVTSKGIPLNALMISMAVSCLSLVSSIVAPG
                     TVYVVMVAIAGFAGVVVWMSIALSQLLFRKRFLKKGGNVKDLTFRTPLYPLMPIAALLL
                     CSASCIGLAFDPNQRIALFCGVPCIILCYLIYHFKRNVTKAKKISQEEYQADHIL"
     CDS             complement(16957..18258)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_28"
                     /sec_met_domain="Glycos_trans_3N (E-value: 4.6e-23,
                     bitscore: 74.5, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 3.6e-54,
                     bitscore: 177.6, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDIIIKKQNGKELTTEEIQFFVNGYTDGSIPDYQASALAMAI
                     FFQDMSDRERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALDV
                     PVAKMSGRGLGHTGGTIDKLEAIDGFHVELTKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAAELAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLHELVLTLGSQMVV
                     LAKKADTLDEARAKLEEVMKNGKALEKFKDFLKNQGGDSSIVDDPSKLPQAAYQIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDEVIAKVYDNIRIATEAKAPKLIHTLITE"
     CDS             complement(18288..19469)
                     /locus_tag="ctg22_29"
                     /transl_table=11
                     /translation="MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYI
                     LLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALI
                     GILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQ
                     RLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDM
                     LRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGIL
                     GYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFL
                     VSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY"
     CDS             complement(19550..20221)
                     /locus_tag="ctg22_30"
                     /transl_table=11
                     /translation="MSLANIIDHTALKPHTQKADILKLIEEAKTYKFASVCVNPTWVEL
                     AAKELKGTGVDVCTVIGFPLGANTTETKAFETKDAISKGATEVDMVINIAALKDKEDDV
                     VEADIRGVVEAAAGKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     KEDIALMRKTVGPDIGVKASGGVRTKEDVDTMVEAGASRIGASAGVSIVKGENASGGDN
                     Y"
     CDS             complement(20212..20337)
                     /locus_tag="ctg22_31"
                     /transl_table=11
                     /translation="MICDTFKPFIEQNFNYQFTYVQKSVMLKNILTKKEVCEGCH"
     CDS             complement(20327..21268)
                     /locus_tag="ctg22_32"
                     /transl_table=11
                     /translation="MDREKQQLSIEAARLYYQSDYSQQQIAEQLNISRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDALGSILEEKYGLLEAHVVFSPTPDYAGITHDLSRYGAEYMHE
                     TVKDGDIVGVSWGTTMYQIAQNMQPKQVKGVEVVQLKGGISHSRVNTYSAETIQLFAEA
                     FQTMPRYLPLPVVFDNADVKRMVEKDRHIERIIEMGKQANIALFTVGTVRDEALLFRLG
                     YFNEEEKALLKKQAVGDICSRFFDAKGNICSSAINDRTIGVELGDLRLKERSILVAGGS
                     RKVSSIHGALTGKYANVLIIDQHTARALVNDL"
     CDS             complement(21402..22229)
                     /locus_tag="ctg22_33"
                     /transl_table=11
                     /translation="MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGILAFMTA
                     AGAGRAKDSSGALQTLSRMPYGSLLLFLIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLS
                     RRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAGFIV
                     FAIVQFMKGVRAAFMKEFETSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMT
                     ADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK"
     CDS             complement(22302..23414)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_34"
                     /sec_met_domain="EutH (E-value: 1.1e-141, bitscore: 465.6,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVNDAVVFILAAFLLWGAADYCLGNRWGLGERFADGFKAMGPLA
                     LSMIGIVSLAPVLAAILIPIVAPFYTAIGADPSSFANTILAIDMGGYALAGEMAKDPQA
                     GLFSWVFLGTMMGPAIVFTIPVALGIIEKEDHPYFAKGILIGLCTVPIGCLIGGLCAGF
                     DIGMIGKNLLIPSLLSAVIAFGLWRYTDRMIQLFHLFGKAVSVVAIIGLAAVSVETMTG
                     IVLIPGMENVETGIQTTGTIAIALAGAFPMTAFITKTFKKPLQALGKHLHLDETATAGL
                     VTSLAHHIPMLASLKDMTPRGKVINVAFAVSGAFVLGSHLGFVAGMKKEMAAAMIIGKL
                     AGGVTAAAAAAWMTPAQSANQQKRISAGHS"
     CDS             complement(23484..24821)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_35"
                     /sec_met_domain="MmgE_PrpD (E-value: 4.5e-96, bitscore:
                     315.6, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQGLTAGLAEAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGRE
                     DKGIQKLLRLIEDEGGLPLVPIIGQGEKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPS
                     AVIVPALMASAARGHDERLLGAYIVGVEVMARLGASIGSRHYEKGWHNTGTLGAIAAAC
                     AVGYAEGLTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFG
                     GSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAV
                     RQLISEEVISAANTERIEVIFPPGGDAALTERSPKTGEEGRFSVEYVIALALHGHGLTV
                     EHFSSQPIPNGVQTTMGRIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRICEARVDCP
                     KGAPGNELSEEDIKEKLTLTVPQEKARSIITAVEKADIKEFLAHIE"
ORIGIN
        1 cacaacattc aaatggtttc tgcctgagat atggccgggc aaggaggatt tgagttccgc
       61 tgaattcttg agctgagaga gcccttgctt cactgtgcca tagaccattt taatttcctg
      121 tgccatttgt gctcacctca ctttttatgt ttttccttct ctatttcatg ctctatcttc
      181 gtaatttggc gtcttatgga atagacatcg ccctctaatg agtggatttt tccttctatg
      241 ctttcgatga ttccgctgac ttgatcgctt ttgatttgct gatatgcttt gttcattcct
      301 tcacgaatat cttcaaaccg gtgagcatgt gttcctctcc atgcctcccg gttaagatga
      361 ggccggtgaa tgagatgctg ggcctcggag aattcgtgtt tgatttgcct gatttcgtgc
      421 agcactcgtt ttaattgatg gatctgttcc tgcttttcat gtaagtcggc ttttaccgaa
      481 tgtaacaaca tttcactatg catgccgcaa cacctcgtgt ttctatcaaa ctgtgtcaat
      541 tctttacaat acagactatt ttcatattac atgatgggtc atattggata aataggtaat
      601 aggatttgtc ttacacagaa tataaataag tatatttatc tattatcctt ttcattcgac
      661 tttctcgcga ataaaatcct gcttacacag gactataagt gtaggtacaa tcaaccccat
      721 ttgattcgcg gtgccattta caaatatctg ttacctatag tcaataataa tgataaaatt
      781 aggatatcta tctaaatatg gagagagaac aatgaaaaaa aacagtggtt ttcatgaaga
      841 attgcaagaa aagcaccagc tttatccggt tgaacatcgt tttcagcctg ttttaccgaa
      901 agaatatcca gaaattttaa ctttacatat agcaaaacaa tttggcgaaa aaatcaaaac
      961 gcttgttcat catggacaat ataatcaggc ggttgaatta acccaaaaaa tatcttctga
     1021 tcttggtaat gatactgcct tttcaatacc actttcttca gttctttatc atgtaggtga
     1081 cctggatctt cctgtgtcag agcacttttc gctatcacgg ttgaatctac tcggaaacca
     1141 tagagcggat gataattttt ttaaagcatt aaagaatgaa atgttaactg ctgatcgtgt
     1201 ggattttatg gtcagtttta caagatggtc tggtgtccaa cttcttattc caccattaca
     1261 agagcttaat aaacgtaatg tgccagtacg tattatcaca tcaacatata tgggaattac
     1321 tgaacctaaa gcccttaaac agctcatgca atttcaaaat gtcgacttga gaattgtaaa
     1381 tgattatagt caatcgtttc atacaaaagc ttacttattt gaacgtcttt cagggcaaca
     1441 tagtgtcatt attggatcat caaatctttc gcaatccgct ctgaccactg ggtatgagct
     1501 aaatgcaaga ataccagata caaaatatct tccaattttt caacaaacaa aagatgtctt
     1561 taataaaata tgggtcgaaa aaacacaacc ggtcgatgac cagttcttaa aagcttatga
     1621 agaatttcaa gtagctaatc acaaaatgag cgcgtctcgc gtctctcaaa actctcttta
     1681 ccaaacaaaa atacaaccta atgccatgca agaaatagcg cttaaaaacc tcaagaaaac
     1741 gagagaacaa ggtgaggaaa gggctgttat tatcgctgca actggtacag ggaaaacata
     1801 tcttgcagca tttgattttt ccgaatatca accaaaaaaa tatcttttta ttgctcatcg
     1861 tgaggagtta ctaactaaag ccattgaaac atttgaaaaa gtcacaaatg accatgataa
     1921 ctttggattg ttaactggat cgaaaaaaga atggaataaa aggtttttat ttagcacagt
     1981 tcaaaccttg tataaagaag aaacattaaa acggtttgca ccagatgaat ttgattacat
     2041 tgtcattgat gaatttcatc atgcagaagc ctctacctat caatcagtgt tgaattactt
     2101 taaacctgga ttcttattag gtttaactgc aactccagaa cgtttagacg gtaaagatgt
     2161 acttgaaatc tgcaatcata atgttgtcta tgaaatccgc cttcgagatg cgttagaagc
     2221 tgaattgctt gccccatttc attattttgg tattccggat catactgttg attacgataa
     2281 agtgaaaata acaaacgggg tctacgatga acgttcattg gttaatcatt tgaaaaatca
     2341 tgagcgagtc gattatgtaa taaagatgat aaatatgtac ggtttcgacg gagaaagaat
     2401 gtgtgggttg ggcttctgta ctaacgttga acatgcccaa tatatgagca aagaatttaa
     2461 tcaattagga ttccatacaa cttatttaac agggcaagat tcctcagcac aacgtcagaa
     2521 agtgattaga gaacttgaag atccgcatca tagtttagaa ctgattttta cagtagatat
     2581 ttttaatgaa ggcattgata taccaaaatt aaacttactg ctttttttac gaccgactga
     2641 atcaccaacc atatttattc aacagttagg aagaggatta agaaagactg atgataaaga
     2701 gtttgtaacg gtacttgatt ttataggaaa ctatcaaaaa tcgtttgtta taccgctagc
     2761 cctttccgga caaactagtc aaaaatcctt tgataaagat tcattacgag ttgcggttac
     2821 ccatgagttt gcagacttac caggtggatc ttatgtagat cttgcatctg taacgaagaa
     2881 agagatttta cacaaaattg atagtattaa attaaattca gctaccatgc taaaaacatt
     2941 atattatcaa tttaaacgag atattgggcg ttctccagag ctacttgatt ttctttattc
     3001 agatcaagct ccaggtctta ccttttttat aaaaaaatat aagtcttggg tcgaaacgaa
     3061 aagaaaaatg gatgaccttc attctttaga taaagaagta ttaaatgatt cgttagtttt
     3121 aagaatggta tcctggttag agcaacagtt tccgattaag tggccctatg atttattatt
     3181 gttacaatgt ggatttaata tacagagaat cactatagat gatgttaaaa agtctttaga
     3241 agatacattt catttaaaaa tcaaaaatac taatatacac gacaacttga ttaaacgatc
     3301 tatggagcgt ttatccacac cacataagaa acaacaatgg agttttggta cagtggagga
     3361 aaatacgttc atactacaat taaatatttt tgaacgttta tgccatcctc ggtttggtcc
     3421 ttatattaag gagcgtatcc agtatggttt aactgaattt agacgcatga ataatttaga
     3481 agcactttta tctagtgaac tacaactcac cttgtatcaa acatatacta gaaatgaact
     3541 catacattta tttcaatcaa ctgatcaaga gggaacgtgg cgagaaggtg taaggagggt
     3601 taacaataac tacttaattt ttattacatt aaataaatct gaacaagttg aggaccattt
     3661 gttatataaa gattacttta ttgatcccta tcattttcat tggcaaagtc aaaatcaaac
     3721 atcacatgct tctactgtag gtcagaattt aattaaccat agacaaagag aatataaaat
     3781 acatctattc gtacgtaaat ttaacgaaat gcatgatatc accttacctt ttatttatct
     3841 aggtaaagta gattacgtat caagcaatgg ggacaaacct atgaatgtaa tatggaagct
     3901 ccatcagcct gtcccagaaa acttgtatgt tgatttaatt aactagtaca tttacagttg
     3961 gaatatcagc aggtgcccat tcaagtgact caagttcact cacgggcacc catctgagtt
     4021 ccgcatgttc tttggcaaca ggttcaccct caataatttt cgcttgaata gaaatcaaat
     4081 taacaatgat tttctcatat tcgtgatgaa tgtcagcgat aatttcaccg gcttcaattt
     4141 tacaaccaag ctcctcataa atttccctca caagagcttc tcgtgcattc tctccctctt
     4201 caagtttccc tcctgggaat tcccatagat tagccaaaga catggttggc gaacgaagtg
     4261 cacataatat catattctta tcattttgaa ttactgctgc agcaactttg attgtttttt
     4321 tcattttatt ttatccttcc ttgcatttct ttctaaatca aaatgcgatt ttaatactac
     4381 atagtgatct aatctgcaat tttagttaaa ctttatcata ctgaaaagat tatataataa
     4441 acaacataac tttttttgac tatatagagt tattttcaca cactaaaaaa ctacttaagt
     4501 aaaattatct tattctaatg atagtgtctt aatcattctt taacttattt gtttttaaaa
     4561 tagaatttag cagtcccttt attttttctg cctcgccact ctcgtttgtc cttaatctaa
     4621 taaaaggtat ccctgatttc ctcagaatag aatcttttaa ttcatccctt cttttctggt
     4681 cattcgaatt atgataagca gtaccgtcga cctctattac cccagcaggt tcattcccca
     4741 ttttgtaata aagcaaaaag tcaaatcgag ctactgtttt aatgaacttt tgttcctctt
     4801 gatttaaatg agaggtatcg ttaaataaat cctttaaacg gtactccctt ctaaactcaa
     4861 tttttttata ggcttcttct ttaagaatat ctctgagtaa actcgcaata atcctttcag
     4921 atttatactt tgagtcactc tctcgcagtt tattttctcg ttgcactaaa acttcggaga
     4981 attctttata tagtaaatcg aacacagaaa tgacctgact ttcatgatat aaactagctt
     5041 ccgtataata ttccatataa cgtattaact cggagatttc tttgttactt ctcttgaaaa
     5101 tatcgacagc agatactaaa acaaaacgtt tttttgctct cgatacagcg acattgatta
     5161 aagtagcact atcaacaaat tcaatatctt ttttaccgcc cttatcatca agtactgtgg
     5221 agaaaataat tccatcacat tctcttcctt gaaacttatg tacagtatct ttaataattt
     5281 cttctctcat ataacgatta gcagctttta tctgggctct ataaggagca ataaatccaa
     5341 tatcatcaaa atcatgtggg aaaaccttgt ctctaatcat tgcctcttca agggaatcca
     5401 attcacgaac attgtggcgc ccgccttgga atctcatatg atttccttta acagttttta
     5461 ttaaaataat tgaagaatcg tctacttcat catatttagt caaaggaatg aggtttccat
     5521 cataatattg ttcattacaa aacttgatga tcataggatg gcaacgatag tgctccttta
     5581 acaaagtaac aggaatttta ttctcatata cttttaaaac agaatgtaga aggctatttt
     5641 ctacataatc aaagcaaggt tcgattccca tttctccctt tgatatgttc ttatctggaa
     5701 tgtgaggtag ttgttttgta tctccaacaa taattacatt tttagaacag cctagagcaa
     5761 ggatacctgg catcaattct aactgtgagg cttcatctat aattaagtaa tcaaataaga
     5821 aaccatctgg aattgatttc attaaagaga atgcggtact cagaataata ggatatcgat
     5881 ttataaatcg atcaaactgc tttgcatctt tatatttctt gtactcaaag ttctctttct
     5941 taaccgtttt ttgcttatta tgtatataat tttcgaaaat taatgtagag taattttgaa
     6001 ttcgattact tagctcgtca aaatttttgt cgagaagtat ttgatttatt ttatttaact
     6061 cagaatttaa ttcagttagt ttttgcttat agaattgata ttggagttga gaaagcattt
     6121 tctctttatt tagactgtct cctatttgtt tgaagtcata taatccatag tagaaaagat
     6181 atttggtttt cttaaagaag ttcattcggt tttgtttgtt gagtacttcg tcagccataa
     6241 aatttaaaat cttataatta ttaaacttat aaaaaggtaa aagctttggc ttcatggttt
     6301 ctaatgactc aaaatgttgt ttgtagtatt ttttctctgt ttctaggtct tttatttgct
     6361 gttttatcac tgcttgtcga ttttttaact ttaatagttc tttaatagat cctacatcac
     6421 taaagacgct tttcagtaac tctgattctc tctcattctc aatcttccat tcggctatat
     6481 tttgaggaag ttccggaagt tgctcaaaga attttttttg attatcttgg ctacctaatg
     6541 atgcaagaag aaaatcgtag cctgctttct ccattttttc tcttacattg gcaacagcag
     6601 cattattact tgagacaatt gcagcatttt ttcccttcat cactatatta gtaatcaaat
     6661 ttaaaatagt ttgtgttttt cccgtaccag gaggaccttc aattacactt atttgtgaag
     6721 aaaaagcaga ctgaactgcc tgaatctgac ttaggtttaa gccaaaagga aaaaggagtg
     6781 tctctgagtc tttatgcaat cgactttctt tcgagaaata agcatagaga gcactttcta
     6841 ttcttaacgg catacgctga atttcacctt ccaaaatagg tgggatatca ttttgtttta
     6901 tctttaacag ccgctacatg tctaaaataa tccaaaagtt gtttaaactt tgcattacct
     6961 aaagtaatct tttcaatatc tttttcttta taaatatatt tccggtcatt cccactaaaa
     7021 gtcaaaacag catacttttc tccatatatt ttaacgctat ctatatttgc ttttacattc
     7081 ccttttagaa ctagtcgttc ttgcttgtta atgaccaatt ttcgaacagg ggtaattata
     7141 cacctatcta attcttcact tttcttcatt ccattgttca atgtaaaatg aacaattatt
     7201 ttagcattat ctcgtttaga taattgccat tctttaattt gatcagaata tgttgtatta
     7261 cctacctcaa tgcttacacc cgtcaaatta ttccctccaa aaacaactta tttatctata
     7321 tgaaattgtt attttttgtt atagtataca aaattaataa ggtgttttca aaatacctaa
     7381 atatgaagta agtaagaaaa gaaccttttc tttttcaaga aaaggttctt aaaaataatt
     7441 ttatccttta agcttactcc cccatacagc ctcaccgctg ccattcaaca cactaaacgt
     7501 catgacgttc ttctctcgca ccgaatccca ctggcgtaaa aataccccgt tatacttctt
     7561 gcccgctaac gtgatgtcgg ctgtgttttt tccggttttc ttccatgttc ccgtcatttc
     7621 cccggaaatg ctgtggtttt tgttgagctg gatgttgatt gtttttttga tgtcggctga
     7681 gatgtctttt ccgtgcttga tgagtttgta cgttcctgta atgtcttttt gttttacttc
     7741 tttcagtgtt tcgcctgcgt aacgatatgg cgctgttacc ggccagccgt ctttgttcat
     7801 gaacaattgg tggactctga cttcgtgttc ttcacccctg cccgggaagc gggtgtggaa
     7861 gattaaatag gagcgtccgg ttttttcgtc atagtatgcg gagttgtggc ctggtgagac
     7921 gtacccggtg cctttttcat tttctgtttc aaaagtgtag ctgcccatga gtttgacgcc
     7981 gtatggttcg atggaacggt cgtcgaagaa tgtgccttcc ttgccgcgga cgtcgagcat
     8041 tggattgcct tctgcatcat agtaagggcc gtccggtttc ttggagcggg ccacacggat
     8101 gttgtagccg cctgttgcat cgagaccgcc atatgatagg tataagtagt agtattgggt
     8161 gtctggatta tagagaacat acgggccttc gattctgctg tggttgccgc cgagcagttt
     8221 tttcccgtat ccctgtccag gaagcgggaa acccgttttc ggattcattt caagtatgaa
     8281 aatgccgcct gagtatgatc cgtacaccat ccacagcttg ccgtctttat caaagaaggt
     8341 atgcgggtcg acgacattcg ggtgtttggt tgcgtcatac ggtgttccat cgctgcttgt
     8401 gccttccatt cctgatttca aaaagatgcc tttgtttttg tatgggcctt cgatgttgtc
     8461 agcaacggca acacccatgg cggatcttgg tgagtcgccg cggcaggcgt tgtagtacat
     8521 gtagtatttg ccgtccgcca gctgcgtgac gtcagcagcc caaagagtat cggattgcgc
     8581 ccattcgaag gtttctttta attctttata gacattcgga atcagtgggt tgtcattgct
     8641 tacgctggtg gtcagctgct gccattgcat gaggtcattt gtttttgctg aagcgagatg
     8701 agatccaaaa acataaaagg tgccatttgt ttcaatgatg gaaggatcat ggacgctgac
     8761 ttctttaaat actggttttt gtgcatagac ggagtttggg agggtgaagg ccatgataag
     8821 agctgcaaga aaacatacac ggaacaatcg gttgaacatc taaacaattc gcctctcttt
     8881 tttattaaat tttaaacgct tacatttctc tatgaagaaa caccggccct ttaggaaggc
     8941 cgaatgtttt catattcaaa cggataggtg attccccact gttcccttac atagtcagac
     9001 tgatgtctgt ctgttttgcg cggaactgct gcttgcatgt cctctccttc atagttcaac
     9061 tcttttgctg tttctcctcc ttgcatcacg tctgtttttc attcgcgtac atgtaataac
     9121 tgctttgtca ggttttgcat caactgtgat acagccattt cgttgtcggc gttttttaag
     9181 atgatgcctg attgcccgtc aacaccagag tcagttggct tggctgtact gaggatgtca
     9241 ttcggctgga catcggccgg ttaccttctg gatatcgtgt gcaatcgctg aaaaagcccg
     9301 tcctgctttc tgcgtcgcgc tattacaata gcaatctaac ttgttaaaga ctgtaaaaaa
     9361 ccttttgact tctgctgctg aaccaattaa tataatactc agttaatagt tatcagaatt
     9421 tttaggaatt gagtgattca tatgacactg cacaaagagc gtcggatcgg acggctgtct
     9481 gttctcctgc tgctgaatga ggcggaagaa agtacgcagg ttgaggagct ggagcgagac
     9541 ggatggaagg tctgtcttgg caaggtagga tcaatggacg cgcataaagt agtagccgca
     9601 attgaaaccg cttccaaaaa gagcggtgtc attcaatctg agggttatcg ggagtcacat
     9661 gcgctttatc atgcgacgat ggaggctttg catggcgtga ccagaggtga aatgctgctg
     9721 ggatcgctgc ttcggacggt gggcttgagg tttgccgttt tgaggggaaa tccttatgaa
     9781 agtgaagcgg aaggcgattg gattgctgtc tcgctttacg gaacaatcgg ggcgccgatt
     9841 aaaggtcttg agcacgagac attcggtgtt ggaattaatc acatatgaaa cagcccatag
     9901 atcttagacg atagggggct atgcgtgaaa acagatgttc acagcatagc tcctttttgt
     9961 atgggcgctt taccaaagta aagacaaagg agttgggctt atggtgactt tagacggttc
    10021 ttcattgact acagccgacg tcgctcgtgt gctgtttgat tttgagaaga cagcggcttc
    10081 tgaggaaagt atggagcgcg tgaaaaaaag cagagcggca gtggaacgga ttgtacgcga
    10141 cgaaaagaca atctacggca tcaacaccgg atttggcaaa ttcagcgatg tcctgattca
    10201 gaaagaagac tcggcggcgc tgcagctgaa tttgatcctt tctcatgcct gcggagtcgg
    10261 cgaccctttt cctgagtgtg tttccagggc aatgctgctt ttgcgcgcca atgcgctgtt
    10321 aaaaggcttt tccggtgtac gcgctgagct gatcgaacag ttgcttgctt ttttaaataa
    10381 acgcgtccat cctgtcatcc ctcagcaagg atcacttggc gcaagcggag atctggcgcc
    10441 gctttcccac ctggcgcttg cgctgatcgg acaaggagaa gtcttttttg agggggaaag
    10501 aatgccggca atgacaggct tgaaaaaagc cggtattcag ccgatatcgc tgacatctaa
    10561 ggaagggctt gccttgatta acgggactca ggccatgact gcaatgggag tggtcgccta
    10621 cattgaagct gagaaactag cctatcaaac agaacgcatt gccagcttaa cgattgaagg
    10681 tttgcgggga attatcgatg catttgacga ggatattcac tcagcccgcg gctatcagga
    10741 gcagatcgat gtcgcagaac gaattcgctt ttatctatct gacagcggcc tgacaacctc
    10801 ccagggagaa ctgcgggttc aggatgccta ttcattgcga tgtattccgc aagtacacgg
    10861 tgcgacttgg cagacactag gctatgtcaa agaaaaatta gagattgaaa tgaacgcagc
    10921 tacagacaat ccactcattt tcaatgatgg tgacaaagtg atttccggcg gaaactttca
    10981 cggacagccg atcgcctttg ccatggattt tctgaaaatc gcaatttcag agcttgcgaa
    11041 tatcgcagag cgcaggatcg aacgacttgt gaatccgcag ctgaatgacc tgccgccgtt
    11101 cctgagccct catcccggtc tgcaatccgg tgcaatgatc atgcagtacg ccgcggcctc
    11161 actcgtttct gaaaataaaa cactggccca tcctgcaagt gtggattcca ttccgtcatc
    11221 cgccaaccaa gaggaccatg tcagcatggg aaccatcgcc gctcggcatg cttatcaggt
    11281 gatcgcaaat acaaggagag tcattgcgat cgaagcgatt tgcgcattgc aggctgttga
    11341 atacagaggc atagaacatg cagcgtccta tacgaaacag ctttttcaag aaatgagaaa
    11401 agtcgtgccg tccattcagc aggatcgtgt tttttcctat gacattgaac gcttgactga
    11461 ctggctgaag aaggaatctt taatacctga ccatcagaat aaagaactaa gggggatgaa
    11521 catatgactg atgtaaaaaa atcaatccgt gccaacagag gaacagagct tgaatgctta
    11581 gggtgggagc aagaggcagt gcttcggatg cttcgaaaca accttgatcc agaagtcgcc
    11641 gagaagccgg aagacctcat cgtatatggc gggatcggca aagccgcacg ggattgggac
    11701 gcttttcacg ccattgagca ttccttgaaa acattaaaaa atgatgaaac attgctcgtg
    11761 caatccggaa agcccgttgg catgttccgt acacacccgc aggccccgcg cgtgctctta
    11821 gcaaattctg ttcttgttcc gaagtgggca gactgggagc atttccacga acttgagaaa
    11881 aaagggttaa tgatgtacgg acagatgacg gctggcagct ggatttacat tggctcacaa
    11941 ggcatattgc aaggaaccta tgaaaccttt gctgagctcg cgcgacagca cttcggaggc
    12001 agcttaaaag gaacattgac gctgacagcg ggtctcggcg gaatgggagg cgcccagccg
    12061 ctgtctgtca cgatgaatga aggcgtcgtt attgccgtcg aggttgacga gaaacgcatc
    12121 gacaagcgga tcgaaacaaa atactgcgat cgaaaaacag catcgattga ggaagcctta
    12181 gcttgggctg aagaggcaaa gcgggcagga aaacctttgt ccattgcact tctcggaaac
    12241 gcagctgagg tgcatcacac acttttgaac cgaggcgtca aaattgatat tgtgacagat
    12301 cagacatctg cccatgaccc tttaatcggt tatgttcccg agggctattc ccttgatgaa
    12361 gctgaccgtt tgcgtcaaga caatccagag ctttacgtgc gccttgcgaa gcaaagcatg
    12421 aaaaaacatg tcgaagccat gctggccttt cagcaaaagg gctctattgt atttgactac
    12481 ggcaacaata tccggcaagt cgcaaaggat gaagggctgg aaaatgcctt cgattttccg
    12541 gggtttgtcc ctgcctacat ccgcccctta ttctgtgaag gaaaagggcc gttccgttgg
    12601 gcggcgcttt ccggagatcc ggcagatatt taccgtacgg atgcgttatt aaaagagctg
    12661 tttccgacaa ataaagccct tcaccgctgg attgatatgg cacaggaaaa agtcaccttc
    12721 caaggcttgc cgtcccgtat ttgctggctt ggatatggag aacgaaaaaa gatgggcctc
    12781 gccattaacg agctggttag aaccggggag ctaaaagcgc ctgtcgttat agggagagat
    12841 catttggact gcgggtctgt cgcctctcca aatcgggaga cagaagcgat gaaggacgga
    12901 agtgacgctg ttggtgactg ggctgtgcta aatgcgcttg tcaacacggc ggcgggtgca
    12961 agctgggttt ccttccacca tggcggcggc gtcggaatgg gctattccct tcatgccggc
    13021 atggttgcag tggccgatgg aagtgagctg gctgacgagc ggctcgcgcg ggtcttaacg
    13081 agcgacccag gaatgggcat tatccgccac gctgacgcgg gttatgaacg tgccgttgaa
    13141 gtagcgaagg aacaggacat tatcgtgccg atgcaaaaat aaaggagtga tgacatgcca
    13201 aagcaaattg atacgattct catcaacatc ggtcagcttt tgacgatgga aagcagcggc
    13261 ccgcgggcag gcaaaagcat gcaggatctt catgtgatcg aagacgctgt tgtcggcatc
    13321 catgaacaga aaattgtgtt cgccggacaa aaaggggctg aagccggtta cgaggcagac
    13381 gaaaccattg actgttcggg acgccttgta acgcctggcc tcgttgatcc gcacacccat
    13441 cttgtatttg gcggatctcg tgaaaaggag atgaacctta agcttcaggg catttcatat
    13501 ttggatattc tggcgcaggg cggcgggatt ctgtctacag tcaaggatac cagggcggct
    13561 tcagaagaag agctgctgca aaaagcccat tttcatctgc aaagaatgct gtcctacggc
    13621 acaaccacag cagaagtgaa aagcggctac ggcttggaaa aagagacaga gctcaaacag
    13681 ttgcgtgtcg caaagaaact gcatgaaagc cagcctgttg atcttgtttc cacatttatg
    13741 ggagcccatg cgattcctcc cgaatatcaa aacgatccag atcaatttct ggatcaaatg
    13801 ctttcccttt tgccggaaat caaagagcag gagctcgcca gctttgctga tatttttaca
    13861 gaaacaggcg tttttacagt cagccaatcc cgccgttatt tacaaaaagc agctgaggca
    13921 ggcttcggat taaaaataca cgcagatgaa atcgatccgc ttggaggagc tgaattagca
    13981 ggtgaactaa aggctgtctc agccgaccat ttggtaggtg catcggacga aggcataaag
    14041 aaattggctg aggcaggaac gatcgccgtc ctcttgccgg gcacgacatt ttatcttggc
    14101 aaaagcacat acgccaaggc tagagctatg attgatgaag gtgtatgtgt cagcttggca
    14161 acggatttta atcctggcag ctcaccgact gaaaatatcc agctgattat gtccattgcc
    14221 gcgcttcatc tgaaaatgac tgcagaagaa atttggcatg cggtcacagt caatgccgca
    14281 tacgccatag ggaaaggaga ggaagccggt cagctcaaag tcggccgctc agctgatcta
    14341 gtcatttggc aagcctcgaa ctatatgtat attccgtatc actacggagt caatcatgta
    14401 catcaagtca tgaaaaacgg aacaattgtt gtcaacaggg agggagccat tcttggataa
    14461 gtaccctttt ctcagagagg ccggatcttc gtttaaagac cgggatgtca caaaaatgag
    14521 cgacctgatc gcaacatggg acggccagga cattaaggga ccggcgttga taggtgtccc
    14581 cctatcaaaa tcctccatca gtcattcagg cgcttccttt gcacccggaa caatacgcca
    14641 ggctctgaaa cattcatcag cctattctgc tgagcttgga gagcacgtcg tatcagagct
    14701 tctatatgat ctgggggata tcgatattca tgtcactgat atcgtaaagt cacatcatca
    14761 cattttccaa actatgcacg ctctgctttc ggaccatccg gattgggtgc cgctcatact
    14821 cgggggagac aattcgatca gctactccac cataaaagcg atagcacaaa cgaaaggaac
    14881 gacagcagtg attcaatttg atgcccatca cgatgttcgc aatacggagg acggggggcc
    14941 gacaaacggc acccccttcc gccgcctttt ggatgaagag attattaaag gtcaacattt
    15001 gatccagctg ggtatcagag aattcagcaa cagccaggcc tatgaagcgt atgcaaaaaa
    15061 acataacgtg aacattcaca cgatggacat gatccgggaa aaaggactca tctccacgat
    15121 aaaagaggtt ttgccagccg ttcaaaatag aacagatttc atttttatat ctgttgacat
    15181 ggatgtctta gaccagtccc atgcacccgg ctgtccagcg attggcccgg gcggcctcta
    15241 tacagacgaa ttgcttgaag cagtcaagta catcgcacaa cagcccaatg ttgccgggat
    15301 tgaaattgtt gaagtcgacc ctaccatcga ttttcgagat atgacaagca gagctgcagc
    15361 tcatgttctg ttacacgcat taaaaggaat gaaactctcc ccattcaagt gatcttctgg
    15421 caggttgtat tttgggtata agaactcatc tgcctaagga atggcagcta aaaggagggc
    15481 gagatagtga atcttcagga gaacagcagc caacagctaa aacgcacaat gaaaagcagg
    15541 cacctattta tgatttcatt gggaggcgtc ataggcacag gacttttcct cagtacaggc
    15601 tatacgctac atcaagccgg gcccggtggt acaatactcg cttatgtaat cggcgggttg
    15661 atgatgtacc tcgtcatgca atgtctcggc gaattgtcgg ttgccatgcc ggtgaccggc
    15721 tcttttcaaa aatatgctac aacattcatc ggcccatcta ccggttttat ggtcggcatt
    15781 atgtactgga tcaattgggt ggtgacggta ggctctgagt ttaccgcatc cggtattctc
    15841 atgcaacgct ggttccctga cagcagtgta tggatgtgga gtgcggtttt tgcagccctt
    15901 ctttttatat gcaacgcatt ttcagttaag ttatttgcgg aaactgaatt ttggttttcc
    15961 agcgtaaaga ttgtcaccat tattttattt atcattttag gaggagccgc catgtttggc
    16021 ctgatctctt taaacggaac ggcggatgct cctatgctgt caaatttcac agaccatggc
    16081 gggctgtttc cgaatggttt tctcgccgtt tttattgcga tgatttctgt aagcttcgcc
    16141 ttttccggta cagagttaat cggcgttaca gcaggagaat cagcaaatcc tcaaaaagat
    16201 attccgcgat ccatccgtaa tgttgcatgg agaaccgtga tttttttcat tggcgctgtc
    16261 ttcatattat ccgggttgat ttcatggaag gacgcaggcg tgattgaaag cccgtttgtc
    16321 gccgtatttg cggagatcgg aatcccttac gctgctgata ttatgaattt cgtgatatta
    16381 acagccttgc tgtctgtcgc caactcaggc ttatatgctt cgacccgtat gatgtggtcg
    16441 ttagcaaatg aaaacatgat cagctcccgt tttaagaaag tgacctctaa aggcattcct
    16501 ttaaatgcct taatgatcag tatggctgta tcttgtttat ctctcgtttc cagtatcgtg
    16561 gccccgggaa ctgtctatgt ggtgatggtc gcaattgctg gatttgcagg agtcgtggtc
    16621 tggatgagca ttgccttgtc ccagctcttg tttcgaaaga gatttctgaa aaaagggggg
    16681 aatgtaaaag atctgacatt tcgcacgccg ctttatcctc ttatgcctat agccgctctc
    16741 ttattatgtt ctgcttcttg tatcggtctt gcttttgatc ccaatcaaag aatcgcactt
    16801 ttctgcggag ttccttgtat catcctttgc tatctgatct accatttcaa aagaaatgtt
    16861 acaaaagcga aaaaaatcag ccaagaggaa tatcaggctg atcacatcct gtaatcaaaa
    16921 aagcacaccc cactcaggat gggatgtgct ttatttttat tcagtaatca acgtatgaat
    16981 cagcttcggc gccttcgctt ccgtggcgat gcggatgttg tcatagactt ttgcgatgac
    17041 ttcatcaacg ttttcgcggt tggcgtaaag cgtcacgagc ggttcccctt tttctacttt
    17101 gtcgccgacc tttttgcgga gcatgatgcc gacggctaaa tcgatctcat cttcttttgt
    17161 ggcgcgaccg gcacctaaca gcatcgccgc gacgccgatt tcgtccgcaa cgatttcaga
    17221 gacgacaccc gcttctttgg caggcacatc aatttgatat gcggcttgcg gaagcttaga
    17281 cggatcgtca acaattgagc tgtcgccgcc ttggtttttc aggaaatcct tgaatttctc
    17341 aagcgctttg ccgtttttca tgacttcttc cagcttcgct cttgcttcgt ccaatgtatc
    17401 ggcttttttc gcaagcacaa ccatctggct gccgagcgtt aagacaagct catgaagatc
    17461 ctcaggtccc tcgcctttga gtgtgtcgat cgcttctttg acttcaagcg catttccgat
    17521 cgcaaagccg agcggctggg acatgtctga aatgacagcc attgtttgac ggccgacgtt
    17581 atttccgatg cgtaccatcg ctttggcaag ttcagctgcg tcttcttctg ttttcatgaa
    17641 ggcgcccgct cccgttttta cgtcaagcac gatggcgtcc gccccggcag cgattttttt
    17701 gctcataatc gagcttgcaa tgagcggaat ggaattgacc gttcccgtta catcacgaag
    17761 cgcgtacagt tttttatcag ccggcgttaa attgccgctt tggccgatga ccgcaacctt
    17821 gtcgcggttc acaagtttaa taaattcatc cttcgtcagt tccacgtgga agccatcgat
    17881 tgcctctaac ttatcaatcg tgccgcccgt atggccgagg ccgcggccgg acatcttggc
    17941 aaccggcaca tcaagagccg caacaagcgg agcgagaacg agtgttgtcg tgtcgccgac
    18001 gccgccggtg gagtgtttat ccactttaat tccttcaatg gcagaaagat caatcgtttc
    18061 accggagttc accatagcca tcgtcaagtc cgcgcgttca cggtcactca tatcctggaa
    18121 gaaaatcgcc atagcaagcg cgcttgcctg ataatcagga atgcttccgt ctgtatagcc
    18181 gttcacgaaa aattgaattt cttcagtggt gagttctttt ccgttttgtt ttttgatgat
    18241 gatatctacc attctcatat ttggtcaccg atccttttcg attaagttca gtaaatcaag
    18301 cccacaattg ctgctgataa aaagctgaca agcgtagcac cgtataataa tttcaagccg
    18361 aaacgagcga cgacatttcc ttgcttttca ttcagtcctt ttacggcacc ggcaatgatt
    18421 ccgattgagg agaagttcgc aaatgacaca aggaataccg atacgatcgc tgttgtacgg
    18481 ccgctgaaat ggaaaccgtt ttgcgtaagc gacgtcatgg cgacaaattc attcgatacc
    18541 atttttgttg ccataatgct tcccgcatta acagcttcat tccatgggat acccacaaga
    18601 aaagcgaatg gagcaaacac atatccaaga atgccttgga acgaaatacc gaatactgca
    18661 ttaaaaatgc cattgatcaa ggcaataatc gcgacaaatc ctatcagcat cgcagcgacg
    18721 acaaccgcta ctttgaaacc gtcaagaatg tattctccga gcacttcgaa gaaggattgt
    18781 ttttcctctt cctcaacacg aagcatatcc tcttcttttg caacctcgta cggattgata
    18841 atagaagcga taatgaaacc gccaaataag ttcaaaacaa gcgctgttac aacatattcc
    18901 ggtttcagca ttgtcatata cgcgccgaca atcgacattg atacagttga catcgcagag
    18961 gcgcaaagcg tgtacaagcg ctgctgattt aaaagaccga gttctttctt caaggagata
    19021 aatacttctg actgccctaa aatcgcagaa gccactgcgt tatacgattc caatcttccc
    19081 ataccgttta ccttgctgag ggcaaggccg atatatctaa taataaacgg gaggactttc
    19141 cacttttgca gaattccgat cagagcggaa ataaacacga ttggcaagag aacattcata
    19201 aagaatgtcg tttggtccgc attcaccaag ccgccaaaca caaagttaat tccctctgcc
    19261 gcgtattcaa gcaggtaacc gaatcctttt gcaaatcctc ccacgaggaa attccctatt
    19321 ccggtattga ggagaatgta gccaagaata aattgcaaaa tgagcataac aacaattggg
    19381 cggatcttaa ttcttttttt gccgctgctc gcgatccacg cgaggcctaa aaacacgatt
    19441 aaaccgataa tcccaatcaa atacttcata tgtgtttctc ctttatttgt attcgcttac
    19501 aatcactgtt tcctcagaaa acggaaagca gtctgccttc cgtcagctct taatagttgt
    19561 ctccgcctga tgcattttct ccttttacga tagaaacgcc tgcgctggcg ccaattcggc
    19621 ttgctccggc ctctaccatt gtgtctacat cttctttcgt tctgacgccg ccagatgctt
    19681 tcacgccgat atcaggccct actgttttgc gcattaaggc gatatcttcc ttcgttgcgc
    19741 cgcctgtaga aaagcctgtt gatgttttta cgaaatccgc tcccgcagac accgctaaac
    19801 ggcatgcacg ttctttttct tcatcagtca gaaggcacgt ttcgataatg actttgacaa
    19861 gcgcttttcc ggctgcagct tccactacac cgcggatatc agcttccacc acatcgtctt
    19921 ccttgtcttt taaagcggca atattaatga ccatatccac ttcagtggcg ccttttgaaa
    19981 tggcgtcttt tgtttcgaac gcttttgttt cagttgtatt ggcaccgagc gggaagccga
    20041 tgaccgtaca aacgtcgact ccagttccct taagctcttt tgcagcaagc tccacccatg
    20101 tcggattgac acatactgaa gcaaatttgt atgttttcgc ttcttctatt aattttagaa
    20161 tgtccgcttt ttgtgtatgc ggtttcaaag ctgtatgatc aattatgttg gctaatgaca
    20221 tccttcgcac acttcctttt ttgttaagat attttttagc ataaccgact tttgaacata
    20281 tgtaaattgg taattgaaat tttgttcaat gaaaggtttg aacgtgtcac aaatcattaa
    20341 caagcgccct cgcggtatgc tggtcaatga ttaaaacgtt ggcatatttt ccggttaatg
    20401 ctccgtgaat ggaagatact tttctgcttc cgccggccac taaaatggag cgttccttca
    20461 gtctgaggtc tccaagctca acgccgatgg tccggtcatt gatggcgctg ctgcaaatat
    20521 tccctttcgc atcaaaaaag cgtgaacaaa tatcccccac ggcctgtttt ttcagcaggg
    20581 ctttctcttc ttcgttaaaa tatccgagcc ggaacaacag cgcttcgtca cggacagttc
    20641 ccaccgtgaa gagagcgata ttcgcctgct ttcccatctc gatgatccgc tctatatgac
    20701 ggtctttctc caccattcgc ttcacatccg cattatcaaa cacgacggga agcgggagat
    20761 agcgcggcat cgtttgaaaa gcctctgcaa acagctgaat cgtttcagcc gaatacgtgt
    20821 ttacccggga atggctgatg ccgcctttca gctggacgac ctcgacgcct tttacttgct
    20881 tcggctgcat gttttgcgcg atttgataca tggtggttcc ccagctgacg ccgacaatgt
    20941 cgccgtcttt taccgtttca tgcatatatt ctgcaccata gcggcttagg tcatgtgtaa
    21001 ttcctgcata atcgggtgtc ggggaaaaca caacatgcgc ctcaaggagc ccgtatttct
    21061 cttcaagtat ggaaccgagc gcatccaaat cctcaaaagg gtccatgacg cgaatctgga
    21121 catacccttt ttcctttgca tattgcagca gccgggaaac ggttggcctt gaaatgttga
    21181 gctgctcagc aatttgctgc tgactgtagt cagactgata gtaaagcctt gccgcttcta
    21241 tgcttaattg ttgtttttcc cgatccattc tgcacctccc tgtggatcag tcctgataaa
    21301 actgcttttt atttgctttt attatacagg ctggcgccgg ctttcatcca cctgatttct
    21361 aagaaactga aaaacgatct gggcgcggac ctgcccagag cttatttctc ccaggtcata
    21421 tgctgataaa tgcctttcat aatggcgtac attccatata ggatcaggcc taatgccaat
    21481 atagacagaa tcaatttgcc atgcggctgc tgcgcgagtt cggcgagcgc gccgtcaaag
    21541 cctcttgtgt cgtcgggatc agcggtcatg gctgtcttga tgagaaaata gccgatagcc
    21601 gagaaaataa tggcccgggc gatattgcct gcgcgtccgg tgtttttcgt gatgcatatc
    21661 atttgtttgt tcatttttga cgtttcaaat tctttcataa aagcagcccg aacgcctttc
    21721 ataaattgaa caatcgcaaa tacgataaaa cccgcacccg taagccctgt gagccactgg
    21781 ccgaacggct gcgccaatac ataagcggac cacgtctgtt ctgaagtgcc gccgtcccct
    21841 tggccaaaca caaatcgcaa ggcattccaa gcgatggatg tgtaaacggc ggcactgaaa
    21901 aagtttccta ttctccgtga caggcctcgc ctgctgtttc cgtggccctc cgtgtccttg
    21961 atcgcgctta acaccatcca gatcacatag ccgataaggc cgatgcctat taaaaaaagc
    22021 aatagtgacc catacggcat gcgtgatagc gtttggagag ctccgctcga atctttcgcg
    22081 cggcctgccc cggcagccgt cataaatgcc aaaatcccaa gcagaataaa aacgccgccg
    22141 aatgcaaaat aaccaagcct cccgaatcgt ttgatccaag gcttggtttc ttgttttatt
    22201 tttgacatgt accggtcttt caccgccatg tgtccaaccc tctttcacag aaatctttac
    22261 tgtaacattc ccgattggac aaagttgaaa cagcttctgc ctcagctatg gccggctgag
    22321 atacgttttt gctgattagc tgattgtgca ggtgtcatcc aagcagccgc tgcggcagct
    22381 gtgactccgc ctgctaattt cccaatgatc atggccgccg ccatttcttt tttcattcca
    22441 gccacaaaac cgaggtggct gccgagtaca aaggcgccgc tgaccgcaaa cgcgacattg
    22501 atgacctttc ctctcggcgt catatccttt aatgaagcca gcattgggat atggtgcgcc
    22561 aaagaggtca ccaagcctgc tgttgctgtc tcatctaaat gaaggtgttt ccccagggcc
    22621 tgaagcggtt ttttaaaggt ttttgtaata aaagccgtca ttggaaacgc ccctgccagg
    22681 gcaatggcga tggtccctgt cgtttgtatc cctgtctcga cattctccat tcccggaatc
    22741 agcacaatgc cggtcatcgt ttcaacagaa acagctgcaa gcccgataat cgcaaccaca
    22801 ctgaccgctt tcccgaagag atgaaacaac tgaatcattc tgtcggtgta tcgccataac
    22861 ccaaaagcga tcacagcaga taacagactc gggatcagaa gatttttacc tatcatgccg
    22921 atgtcaaagc ctgcgcataa tccgccgatt aagcaaccga tcggcactgt gcacagcccg
    22981 attaatatgc ctttcgcaaa atacggatga tcctcttttt cgatgatgcc aagagcgacg
    23041 ggaatcgtga agacgattgc cggtcccatc attgttccta aaaacaccca tgaaaacagc
    23101 ccggcctgcg gatctttcgc catttctcca gccagcgcat atcctcccat atcaatcgcc
    23161 aaaatggtgt tcgcaaagga agaagggtcc gcgccaatcg ccgtgtaaaa cggagcaaca
    23221 atgggaatca ggattgctgc cagcacgggc gccagcgaca caattccgat catggacagc
    23281 gccagcggcc ccatagcctt aaagccgtcc gcaaaccgct cgcctagccc ccatctgttt
    23341 cccaaacaat aatccgccgc tccccatagt aaaaaggcag ccaaaatgaa tacaaccgcg
    23401 tcattcaccg tcatggtttt ctcctttttc aaacgtatga ttggttttat catatcatct
    23461 gaaatcaccg aatagagttg atcttattca atatgagcta aaaattcttt tatatcggct
    23521 ttttcaacgg ctgttatgat gctccgcgct ttttcttgcg ggaccgttaa tgtcaatttt
    23581 tcttttatgt cttcttcaga cagctcattt cctggcgccc cttttgggca gtccacacgc
    23641 gcttcgcaaa tccggccgtc tgataaatag gcccggacaa tcgtgaaacg gccttttgga
    23701 acggcatgag gagccggctg aatagcattg tcatatacgc gctgaattcg ccccattgtc
    23761 gtttgaaccc cgtttgggat cggctggctg ctgaaatgtt caacggtcag gccgtgtcca
    23821 tgcaaagcaa gagcaatcac atattcaacg ctgaaacggc cttcctctcc agtttttgga
    23881 gatctttccg tcaatgcagc atctccgcct ggcggaaaaa tcacttcaat acgttcggta
    23941 ttggcagcag aaatgacttc ttcagagata agctgtcgta ccgcatctgc agcatggtgt
    24001 gccgctgaac aaaatggata gattttaaac cataggcccg gctgcacaat tctccacggt
    24061 gccccccaat cgtttagcaa cgtatgttgt gctttttcaa cgtcaccgta cagactgaag
    24121 aaaccagttt ctccatcaag tgccgtgcgg gacccgccaa attctgattg ggccagctta
    24181 acggccagca agccagcctg agccgccaaa ccggcatgca gcggtttcat ttctgttcca
    24241 aattgcaccc tcatcccagc agattgcgta gccgcaaaac caatcgcttt ttccagctct
    24301 tcctgagtca gtccctcagc ataacctacg gcgcaggcgg cagcgatcgc accaagcgtt
    24361 cctgtattat gccagccctt ttcatagtgt cggctgccaa ttgatgctcc cagccgtgcc
    24421 atcacttcaa caccaacaat ataagcgcca agaagccgct cgtcatgtcc gcgagcggca
    24481 gaagccataa gggccggcac gatgactgca ctgggatgtc ctcttacatc ggagtggaca
    24541 tcatcaaaat ccagtgcatg ggcgataaat ccgttgagca tcgcggattg taatggcgcg
    24601 gccttttcgc cctgtccgat aataggaaca aggggcaggc ctccttcatc ctctatcaga
    24661 cggaggagct tttgaatgcc tttatcttct cttcctgcga atgaagcggc agtaaaatca
    24721 agtaatcctt tttttgcttc gtgaatcgcg tcaactgaat gctcaggttg tgacgttctc
    24781 acagcctctg caagacctgc tgtcagccct tgtttgctca tttgatggtc tccaatacaa
    24841 taaccgccag ctccgcaaag tattgagagg caaccgtaag ggcatcttca tccagtgtaa
    24901 aggccggatg atgccactcc tccgtcccgt tcgttcccat ccagacaaaa aatcccggaa
    24961 tcttctcttg atacagagcg aagtcttctc cgcccggaga ctgctcagcg tgaacggttt
    25021 gatagccaag ccgtgctgca gcttcggatg ccgcattcaa aaatgtgccg tcattctgaa
    25081 cggaaggcaa ataaggaaac cacttgaatt ctgcttgtgc cccatagccc gctgcaattc
    25141 cttcagccac tcgtctcata tgctccggaa cagcctgccg cgcttctttt tgaaaggttc
    25201 gaaccgtccc ctccatttca gcttggtctg gaatcacgtt ccacgacgtg cccgcctgta
    25261 ctcttgtgat actgacgact gcgttttgca gtgagctgat attgcggctg accacagatt
    25321 gcagcccgct gatgatttgt ccggctgcag cgattggatc aatactgtta tttgggatgc
    25381 cggcgtgtcc gcctttccct ttgatgacga tc
//
