LOCUS       c00006_gnlPro..        13823 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AFMAKEIE_6.
ACCESSION   c00006_gnlPro..
VERSION     c00006_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:13:16
            Original ID  :: gnl|Prokka|AFMAKEIE_6
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 42992
            Orig. end    :: 56815
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13823
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[52992:56482]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13823
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13823
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(470..1060)
                     /locus_tag="ctg6_50"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             1345..2910
                     /locus_tag="ctg6_51"
                     /transl_table=11
                     /translation="LFRETEMTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISM
                     DEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDT
                     FNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDE
                     PTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDF
                     LQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPV
                     ARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGK
                     STLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEA
                     RSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEAL
                     VQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGG
                     ITAE"
     CDS             2974..3357
                     /locus_tag="ctg6_52"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDSRCRGRKTPV"
     CDS             3592..4365
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_53"
                     /sec_met_domain="adh_short_C2 (E-value: 5.3e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVAHRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4389..5594
                     /locus_tag="ctg6_54"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             5608..5808
                     /locus_tag="ctg6_55"
                     /transl_table=11
                     /translation="MIIALRTEQSADHAETEHVTREALWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             6465..6761
                     /locus_tag="ctg6_56"
                     /transl_table=11
                     /translation="MPGAVNPPLIVTVSPSVLAVGAAVPPAAYKYVLDVSCIKPITDWL
                     TARKRYVNAASRSRGEPSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             complement(7285..7569)
                     /locus_tag="ctg6_57"
                     /transl_table=11
                     /translation="LILDRSRTIVTDITSRLLVPYPLKVIPDNVRLLSSDVMETESFRV
                     PKSAVWEVKSEYPTMELSSREVAAVALRLMPAERIRVDNNLFMVSILIK"
     CDS             complement(7676..7918)
                     /locus_tag="ctg6_58"
                     /transl_table=11
                     /translation="LTNLFLGKEGVVDVELFDGFSQSCVHENLINLLVAEFQAAVGIVR
                     SAVAKIDAGAKISGDYGNGQGPFCAQRGVNDGPAV"
     CDS             8269..8676
                     /locus_tag="ctg6_59"
                     /transl_table=11
                     /translation="MQSPDSLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLDLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg6_60"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg6_61"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             9818..9973
                     /locus_tag="ctg6_62"
                     /transl_table=11
                     /translation="MRKASSSRNRQQNDNHSKLINSNLFPRFFKNPKSAGNSRRGLPSG
                     LEPGIL"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_63"
                     /sec_met_domain="SucD_FumR (E-value: 4.6e-13, bitscore:
                     41.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLLFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_64"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_65"
                     /sec_met_domain="Fer2_3 (E-value: 2.8e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 9e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.9e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 tttctgtaat gccgtgacat ggaacaagaa aatctcttga tttctacttg ccaccattta
       61 cattggtgcc agcaaacctc cgtggatgcg gaggttccag tagttaacaa acactgtatt
      121 taattcgaat tatgaagaac atcgctatcc tcgccatcgc cggcgccgct tgcctggtcg
      181 cttcctgctc ccagcagcag cagcaacagc aaaccaccgc tcctgctccc gctccggttg
      241 tgcaggccaa gggcaagtaa gtttgcagcg gggttttgcc ctgcaacact agcaaattat
      301 ccaattaatc cgcactcggt gtacgcactg agtgcgtttt tatttgccct gagtccggat
      361 tccctccgcc atttgccgat tcgccgggat tttccttaaa aacggcggat accgcaaacc
      421 gccgcggcgc agcaccgtgt gccggttcct gccggatcag gcttcccctt tattcagcgg
      481 ccgccttcgc ctcattctgc tgatcggact ggaatatccg ctgaaccagc atggggcgtt
      541 tcctggccca cccgggccag accaggtgat gttccatgcc gtaggaatgg ccctccggaa
      601 aggccttgga aacaaatggt tctcgccagt cctcctccca tttgccgcct tcccggtcct
      661 tctgggtcag cgtcaccaga tgcccgcagt tcttccaggc atccagaaca atggagccct
      721 gcaatccctt ccccgcggca ttgacataca cgcaactgtg ctccctgccc gttcctcggt
      781 ctcgaatcgt cagccctatg cggaaatact tcacggggcg gcggcgcagg tcccggtaca
      841 aatcctgctg gacctgccag cacaaccccc tgtcgcgcag gttggaattg accagaatat
      901 tgttcagcca gccaaacagc acagtcctgt tgtcccgggc aatcgcggcg gactggacca
      961 cggccgtgtc cgccagccac ctggcctccg ctccggcagc gggaagagag gcctgatccg
     1021 gcggcagcag cgccaggaag gcattagcca gcccggacat ttgctgctgc acgtaagttt
     1081 gttgtatata atcctccgcc ggaggagtac agcaggaact ccatccgcac aaaagggcgg
     1141 cagcaagcaa aagcctgaat gtctgcgtgg tcggcatggc gcgccaaggc tagcagacta
     1201 cgcgtaaaaa tccagtaaag ctttcaaaaa tgcctgcctc cgccctgacg gctcttgcct
     1261 tcccctttcc atcccggtag aatacatcct ctcttcacca tgctgacgat caaaaatctc
     1321 acaaaatccc acgccggacg gaccttgttc agggaaacgg aaatgaccat taactggggg
     1381 gaacgggtgg ctctggttgg ccccaacgga gcaggcaaat ccaccctgtt ccgcatgatt
     1441 ctgggagaag acacgccgga cgaaggctcc atcagcatgg atgaatacgc catcgtgggc
     1501 tatcttcccc aggaagccag cgaaccgaag gatgaaaccg ttctggaaat cgccctgggc
     1561 atcacgccgg aaatggaaca ggccatccac accatccgga cggcggaaaa cgccaacaaa
     1621 acggatacgc cggaatacgc ggaagccatt gacactttca acgccgccaa cggttaccag
     1681 ctggagccca aagccaagaa aattctcaaa gggctggcct ttcgggaaag cgacttccat
     1741 cgccccgccc gggaaatgtc cggcggctgg atcatgcgcg cgtacctggc caagctcctt
     1801 gtcctggagc cggacctcct gatgctggac gaacctacca accacctgga cctcctgtcc
     1861 ctgctgtggc tccagcgata cctgaaaaac taccccggag ccatcctgat gatttcccac
     1921 gaccgggatt tcatggatga gctggtggaa agcgtgtacg acatcgacaa cgaagaactg
     1981 gtggaatacc gcggcaatta ctcggacttc ctccaacaaa aggacgtgcg cttcgagcag
     2041 cttcaggcgg cctaccgcaa ccagcagaag gaaatagcgc acattcagga atttattgac
     2101 cgtttccgct ccatcaattc caaagccggg caagtccaga gccgcatcaa gcagctggaa
     2161 aagatgaaaa tcattcaaaa accggtagcc cgcaggaaag tatttaaatt caacttcccc
     2221 cagcctccgc gcagcaccca gaaagtcatt gagctggaaa aagtctgcca atcctatggc
     2281 gaccgcaggg tttatgaaaa cctggacctg ctggtggaac gcggggagcg cactgttctt
     2341 gtaggcccga acggcgcggg caaatccact cttctcaaaa tcctggcggg catcatcccc
     2401 attgactccg gacaacgcac tcccggtacc acgacgcgca tcggctactt ctcccaggcg
     2461 cgaacggaaa acctgaatcc ggaaaatacc gtgctggagg aaatcatgaa atgcagcgct
     2521 gaaatccggg aggaagaagc gcgttccatc ctgggttcct tcctgttccg gaggctggat
     2581 gtggaaaaac gcgtcagcgt tctttccggc ggggaaaaat cgcggctcag cctggtcaaa
     2641 ttcctggtgg atccgcccaa cctcctgctg atggacgagc cgaccaccca cctggacctt
     2701 ttgtccgtag aagccctggt gcaggctctg aagcattatg aaggaacact ggtcttcatc
     2761 tcccacgatg tgcacttcat ccgttccctg gcacaaaaaa ccctgcatgt gaaccggggg
     2821 accatcaccg cctacgcagg cggatatgac tattatctgg aaaagtcagg cattctggac
     2881 gatgaaaaag gcggcatcac ggcggaataa ggctcttttt tcagtttccc ctttttcctt
     2941 gccgtggatt tcatcctgcc ttaaaagaac aggatgaagg cttttcttgt tcctctctta
     3001 tattctgcgc ttctgtccgg agcctctctt gcatttggtg aaacggccgc cggaacggct
     3061 tcccccgcag cagcggctcc ggcggaaaaa attccttccg cggaatccct gatcaaccag
     3121 gccttttcct ttgccatcaa tatccagcag acgttggcag gcgttcagga caaggaaagc
     3181 gcggacaacg ccgtcaaaac gctgcaggac attcagaagg acatccggca tttcctccag
     3241 cttcaggata aattgaacga tgcggaaaag gagaaagaag acgccttgat agaaaaaatg
     3301 gaaaaacgaa tggaaatgct ggacagccgc tgcaggggaa ggaaaacgcc tgtttgaggc
     3361 ccgctattac gattccgccg ccttaaagga cattttggaa aattcggatg aattcagcga
     3421 cctggtagaa ccggatgaag acggggcgcc ccccggtgca ctccgggaaa atgaagaggc
     3481 cggacagtag ccctcccgcc ccgtttctcc cccctctttt ttcattcccg gcacgccctt
     3541 tccccgtatg ggttcctgcg cgcccaagtc catttcaagc ttgccggaac cgtgaaaaac
     3601 gggtttactg tgggcagcat gcaaaagtta gcaggtaaaa cagccatcgt taccggcgcg
     3661 ggccgcggaa tcggcaatgc cgtcgcgcac cgcttcgctt cggaaggagc cagggtcatc
     3721 ctgatcagcc gcagtccatc cagctgcggg ggggccgcag aagaaatcaa caaggaattt
     3781 ccggattcct gcaaggccta cccctgcgac gtagcggatt acgcggccgt tcaggaaacc
     3841 atggccgcca ttttgaaaga cttcccgcag attgacatcc tggtgaacaa cgccggcatc
     3901 acgcgggact ccctgatgct ccgcatgaaa gaggaagact gggatgccgt tctggacacc
     3961 aacctgaaaa gcgcgttcaa tacggtcaag gccctccagc gcgttctcat gaaatccccg
     4021 gccgggcgca tcatcaacat gagctccgtc atcggtctcg tcggcaacat cggtcaggcc
     4081 aattacgccg cttccaaggc gggcctcatc ggtttcacca aatcactggc tcaggaattc
     4141 gctccgcgca aagtcacgtg caacgccatt gctcccggct tcatctccac ggaaatgtcc
     4201 aatgccattc ccgacaatct caaggaagaa atcgttaaga aaataccttt gaaagaacaa
     4261 ggttccgtgg aagatatcgc cgccctgacg gccttccttg cctctgacga tgcccgttac
     4321 atcaccgggc aggtcattgc ctgcgacgga ggcatgacga tgtagggcat tccggttttc
     4381 accattccat gcgcggcatt ttccttgttt cctgctttct gggaggaagc gccctgctgg
     4441 ccgggtgccg ggaagaaaat aattcccccc gcccggccac ggaagatgcc gcgcgcatta
     4501 ccagcgcacg ccaatgggga gaaagccgat ccgcgctgca aaaacgggaa ctggaccgcg
     4561 ctgccggtcc tgcccttccc attccggatg acctgccgtc ccgggagctg gtcggcacga
     4621 cgcgccaaat ccatcagctc attgaagctt ccggaaatcc ggcacgtttt gaatcctaca
     4681 cggaaacggt tcccgcggcg ggagcttccc tgcgcatggt cgccataccg ggaggaacgt
     4741 tcctcatggg gagtcccgcg gaagagccgc accggaaacc ggacgaagga ccgcagcata
     4801 aagtgagcat ctctcccttc tggatctcgg aaacggaaat cccctgggaa ctttatacgg
     4861 ccttcatgga aaacgggcgt ccgcgcgcca aggacggtca gcttctggag gaacagccgg
     4921 atgacgaact gtgggactcc gttacgcagc ctaccgcccc ctacaccgcc atgaacctgg
     4981 gcatgggcca cggctatgaa cacggtctgc ccgccatctc catgtcccac cacgccgcca
     5041 gcaaattctg cgaatggctg agcgcccaga ccgggcatta ctaccgcctg cccacggagg
     5101 cggaatggga atacgcctgc cgtgccggct cccccggcgc ctattcttac ggaaacgggg
     5161 aagcctctct ggaccagtac gcctggtact ggaacaactc caatgaccgc taccagaaaa
     5221 caggctctaa aaaaccaaat aagtggggac tccgggacat gcacggaaat gtggcggaat
     5281 gggttttgga ctcttacgtt ccggatgcct acggcaaacg gagcggcttg cccgcgaaag
     5341 accccttggt catcatcccc ggcgcccctc acatcgttcg cggcggttcg tgggaagacg
     5401 acccggacag cctgagaagc gctgcgcgcc gcgccagcac ccccgcctgg aaccgtcagg
     5461 atcctcaaaa ccctaaaagc atctggtacc tgacggacgg aggcatgatc gggttccgcg
     5521 tggtgcgccc catgaacatt ccggacgtta tgacgatgca ccgcctctgg aatttctcca
     5581 agggggagcc gtaaagaaca acccttcatg atcattgcat taagaacgga acaatccgca
     5641 gaccatgccg aaacggaaca tgtcacgaga gaagcgctct ggaactattt cgtccccggc
     5701 tgccatgaac attacctgct ccatatcatg cgcgtcagtc cgtccttcat cccggagctg
     5761 gatgcagtcg ccgtccacgg cagccgcatc gtcgggaaac atcgttgatg caacgtccgt
     5821 catcagggca gacgatggaa aagaatatga agtgctgggc atggggccca ttgccgttct
     5881 tccggaatac cagcgccggg aaataggacg gcggataata ggtatgcggc ggccctccag
     5941 gtctgtgaac tgcaaaaggg gtccctatcc ggcctgaaag gccgctatgt ggaagctgcc
     6001 gtgtaccata tggacgaaaa gcgcgctgcc gaatttgacg gcattttccg gtaaagaaaa
     6061 agctttccgg tactgcgtct caaaaacgtt tccagcaaat tgccgccatg cggaaaaaac
     6121 cggatacggc cccctgcccc cggaaatccc gtaccttccg gagggcatga atcccgcatg
     6181 cggatgagta attcttcctc tctggatata aaaaacaaga gctgttccgc aagaacagct
     6241 ctcatccgcc gatttttcgc catcaggaag ctcaagccct gcggcggcgc atcatcagcg
     6301 cggccagtcc cagcaggccc agggaaaccg tggctggttc cggcaccatt tcccctcgga
     6361 tttccgtgaa aatcggagat aataagctga aagtattggt tccgttggct cccgtaataa
     6421 caacagaatc accaggcgct ccctcggcgt cataatggcc gcggatgccg ggagcagtca
     6481 atccgccgct gatcgttacg gtatctcctt ccgtgttagc agtaggggcg gctgttcccc
     6541 ccgcagcata taaatacgtt ttagacgtat cctgcatcaa gcccatcacg gactggctca
     6601 cggccaggaa acggtatgtc aatgccgcgt caagaagcag gggagaacca tccagggaag
     6661 aaaaactgaa cgtcagatta atccctgctg cagtagttcc cgtattggtg ctccagccga
     6721 tgaccgaatt gtcggagcca ttcagcacca ggaagccgta agtgacatta gcgcccaaat
     6781 tgttggcggc tccgcgcagc gtaaaactgt ccagtctgat ctctccggac agggaggagg
     6841 gagaagagga atcggaagga gccagggaag aagaccccag gctaagataa aacccatgga
     6901 tggtactatt gtaattatcc gtaccgggag tgtaataatt aaaaacggtc gctgcctccg
     6961 aggaaacagc aaagcttccc atcgcgatta aaaatgtcag tgttttcttc atatttatta
     7021 ttccttttgg atggcaactt gtagcgaatt tggaattctc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gactgacccg
     7141 tcatcttagc aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaata
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagca
     7261 caagtacata cattgaacct tgaatcattt tattaagata ctgaccatga ataaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctaagcgct accgcggcta cctctctgct
     7381 ggatagctcc atcgtgggat attcggactt tacctcccaa acggcggatt tcggcaccct
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggataacctt
     7501 caacggatac ggtaccaaca accgcgacgt tatgtctgtg acgatggttc ttgatctgtc
     7561 caaaatcaac actccggaga cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 cagcgggccc gtcgttgaca ccccgctggg cacagaaggg tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggcgacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcaact
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 gaccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatggca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gattccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctggac cttctggatg atgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg ttgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtacttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcggccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggt tgcaacgtca ctgccgccta caaagcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaaaggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaagaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggtaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagttgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gatggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaacacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacactgga aggcacccag taatccagga gaccatactt ggaaatgccg
    13681 gacgaaacct aagcaagccc ccgtccgaca gcgacggccc ccatctttct ccgagagaga
    13741 aaaacattga ttacaggaat tagactgatg cccggaaggg atggcatcct gtcaagggct
    13801 cagcatgaga ggaaaacatt ttc
//
