LOCUS       gnlProkkaKKOACABF_43    3668 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KKOACABF_43.
ACCESSION   gnlProkkaKKOACABF_43
VERSION     gnlProkkaKKOACABF_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:19:07
            Original ID  :: gnl|Prokka|KKOACABF_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3668
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3668
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[106:3667]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      107..3667
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3668
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3668
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             107..3667
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     8.8e-92. Score: 299.4. Matches aSDomain:
                     nrpspksdomains_ctg43_1_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     6.8e-112. Score: 365.9. Matches aSDomain:
                     nrpspksdomains_ctg43_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1035). E-value: 1e-25. Score:
                     81.6. Matches aSDomain: nrpspksdomains_ctg43_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     373.3; E-value: 2.6e-113)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="Condensation (E-value: 1.1e-78, bitscore:
                     250.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.4e-125, bitscore:
                     403.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.4e-18, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQFHLLTILENALQHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGILSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLASEKAENHLFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVKAITQEKVTTAH
                     FIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRLDDQVKIRGYRIEPG
                     EIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLESLLPGYMVPAYMIE
                     MEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNF
                     FDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIRKGTDSPYEAIKPAEK
                     QETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRAFKELIKRHESLRT
                     SFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEEEAAAAFIKPFDLSQAPLFRAQIVKVS
                     DERHLLLVDMHHIISDGVSVN"
     aSDomain        116..1006
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg43_1_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="8.80E-92"
                     /label="ctg43_1_Condensation_Starter.1"
                     /locus_tag="ctg43_1"
                     /protein_end="300"
                     /protein_start="3"
                     /score="299.4"
                     /tool="antismash"
                     /translation="NTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     aSModule        116..3211
                     /complete
                     /domains="nrpspksdomains_ctg43_1_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg43_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg43_1_PCP.1"
                     /locus_tags="ctg43_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       122..160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0001"
                     /evalue="7.50E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg43_1"
                     /protein_end="18"
                     /protein_start="5"
                     /score="9.3"
                     /tool="antismash"
                     /translation="YSLTHAQRRVWFT"
     CDS_motif       185..301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0002"
                     /evalue="3.20E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg43_1"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.2"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       506..571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0003"
                     /evalue="1.30E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg43_1"
                     /protein_end="155"
                     /protein_start="133"
                     /score="24.5"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       905..994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0004"
                     /evalue="1.60E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg43_1"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.0"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       1046..1159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0005"
                     /evalue="6.10E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg43_1"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.5"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        1496..2698
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg43_1_AMP-binding.1"
                     /evalue="6.80E-112"
                     /label="ctg43_1_AMP-binding.1"
                     /locus_tag="ctg43_1"
                     /protein_end="864"
                     /protein_start="463"
                     /score="365.9"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE
                     SIVGILSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLASEKAENHLFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVKAI
                     TQEKVTTAHFIPAMLNSFLDQAEMLALGDGTNLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRLDDQVK
                     IR"
     CDS_motif       1682..1723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0006"
                     /evalue="7.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg43_1"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       1907..1966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0007"
                     /evalue="5.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg43_1"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       2492..2581
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0008"
                     /evalue="7.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg43_1"
                     /protein_end="825"
                     /protein_start="795"
                     /score="56.6"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       2663..2728
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0009"
                     /evalue="6.30E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg43_1"
                     /protein_end="874"
                     /protein_start="852"
                     /score="40.5"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        3005..3211
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg43_1_PCP.1"
                     /evalue="1.00E-25"
                     /label="ctg43_1_PCP.1"
                     /locus_tag="ctg43_1"
                     /protein_end="1035"
                     /protein_start="966"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLATVIRKG"
     CDS_motif       3260..3295
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0010"
                     /evalue="3.70E+00"
                     /label="C1_starter_004-017"
                     /locus_tag="ctg43_1"
                     /protein_end="1063"
                     /protein_start="1051"
                     /score="1.5"
                     /tool="antismash"
                     /translation="YPVSSAQKRIYV"
     CDS_motif       3326..3433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg43_1_0011"
                     /evalue="6.00E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg43_1"
                     /protein_end="1109"
                     /protein_start="1073"
                     /score="54.0"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTSF"
ORIGIN
        1 atagtgcata tatggattat atagtcatat aatttctttt attgacattt ttctgctttt
       61 ttctactttt tcttatcctc ttattatgag aactggaggg aatccgttga gcgaaaatac
      121 ttattcttta acccatgccc aaaggagagt gtggtttacc gaactgctgg agccagatac
      181 cagcatttgc aatctcacag cctgtgtgaa attcaaaggc aatattgagc ttgatactct
      241 agagggagcg ctgaatcatt ccatctcccg caacgacgcc attagatttc agctgttaga
      301 aggagaagag cttgagccgc gattgcacct tactgaatat aaatattatc cacttagaat
      361 aattgatttt tcaaatgttg aaatgataga aatagagcaa tggattcagg atcaagcgag
      421 cattccattt aaactgttca actcgcctct ttatcaattt tacctcctta gaattgactc
      481 tcatgaagtt tggctatttg cgaaattcca tcatatcata atggatggaa tctctttaaa
      541 tgtgatggga aatcaaatta tagatcttta tcaaaaaatg aaaaagaaag atcctttacc
      601 tgatcagccg gaaccttctt acttgagtta catcgaaaaa gagagtcaat atctacaatc
      661 tccgcggttt gcaaaggacc gtttattttg gacgcaaacc tttgagcacc cgttggaata
      721 ccactcgtta gccgaccaga cgtccttaca aaaacagagc acttctgcat ccagagacac
      781 catcattctt tcacctgatc tagagcaaac gattcgaatc ttctgcgaag aacacaagat
      841 caatatcatt tccttattta tggcttcatt ttacatatgc atcagccgaa tcacttctaa
      901 aaaagatctt gccattggca cctactatgg caacagaggg tcaaaggctg aaaaagaaat
      961 gctcggcatg ttcgttagtt ctcttccaat cagaataacg gttgatcctg acacagattt
     1021 tctttccttt gtccgcacaa taggcaggga acagctttct gttatgcgtc atcaacggtt
     1081 tccttataat ttgcttgtaa atgaattaag aaatgaacag aaggatttac acaaccttat
     1141 cggtatatct atgcagtatc agccacttca gtggcataat gcagatgatt ttgactatga
     1201 aacagcgctt tatttcagcg gatacaccgc gaacgagctt tcagttcaaa tacaagaacg
     1261 gatagacaat ggaaccattc aattaaattt cgactatcaa aataccttgt tttctcttga
     1321 ggatattaaa cgaatacaat ttcatctgct taccatactg gaaaacgccc ttcaacatcc
     1381 gcacagcttt ataagagaat tagatatgac gaatacaaga gaaaagcaaa aattgttgta
     1441 tgagtttaac aagacggaag ctgtttcgcc taaagctttc accctgcatg ggctgtttga
     1501 gcgacaggca gctttcacac cggagcggct ggccattcgc ttttcaggcg gttcgctgac
     1561 atacgctgag cttgatatgt acgccagccg gctggctgcg caccttgcgg cacgcggcgt
     1621 cacaaacgaa agtatcgtcg ggatcctgtc tgaacgctca cctgacatgc tgatcgctgt
     1681 ccttgctgta ttgaaggccg gaggggcgta tttgccgctt gatcctgcgt atccaaagga
     1741 gcggctgagc tacatgctga aagacagcgg ggcatcgctc ttgctgacac agccgggatg
     1801 ctccgcaccg aacttttccg gagagacgct tgaagtggac atgacatctc ttgcgagcga
     1861 aaaagcagaa aaccatctgt ttactcctgc tgacggcggt tctctcgcct atgtcatcta
     1921 tacatcgggc tctaccgggc agccgaaagg agtggccgtt gagcaccgtc aggctgtttc
     1981 ctttctgacc ggcatgcagc accagtttcc gctttcagaa gatgacattg tcatggtgaa
     2041 aacctctttt tcctttgatg cgtctgtgtg gcagctgttt tggtgggctc tttccggtgc
     2101 ttcggcgtat ctgcttccgc ccggctggga aaaagactcc gcattgatcg taaaagccat
     2161 tactcaggaa aaagtgacaa cggctcattt tattccggct atgctgaata gctttctgga
     2221 tcaagcagaa atgttagcgc ttggtgacgg gacaaaccta aagcgtgtat tcgccggagg
     2281 tgaaccgctt gcgccgcgta cggcagcccg ttttgcttct gtattgccgc aggtatcatt
     2341 aatccatggc tacgggccga cagaagcaac ggtagacgcg gcattttacg tattggatcc
     2401 agaacgggac agagaccgtt tgcggattcc gattgggaag cccgtacctg gtgcgcgttt
     2461 gtatgtttta gatccgcatt tagccgtaca gccttccggt gtcgccggcg aactatacat
     2521 tgccggagcg ggtgttgcca gaggttattt gaatcggccg gcattaacgg aggagcgttt
     2581 tctagaagac ccgttttacc cgggtgaacg tatgtacaaa acaggagatg tggcgcgctg
     2641 gctccctgac gggaatattg aattcctggg acggttggat gatcaggtga aaattcgcgg
     2701 ctaccggatt gaaccgggag aaattgaagc ggcactaaga agtatagaag gtgtaagaga
     2761 ggcggccgtt accgtacgga cagacagcgg cgagccggaa ttatgcgctt atgtagaagg
     2821 gctccaaaga aacgaagtcc gagcgcagct tgagagcctg ttgccgggct acatggtccc
     2881 agcctatatg atagaaatgg aacagtggcc ggttacacca agcggaaagc tcgaccgaaa
     2941 cgccctgcca gctcctggcg gagcggcaga tgcggagacc tacacggcgc cgagaaacgt
     3001 gactgagatg aagctttctc agctatggga ggacgtgctg aaaaatggcc ctgtcgggat
     3061 tcacgacaac ttttttgacc gcgggggaca ttccttaaaa gcaacggcgc ttgtctcacg
     3121 gattgccaaa gaattcgatg tacaggtgcc gctaaaagat gtgtttgccc atccgacggt
     3181 agaaggactg gctaccgtta tccgtaaagg aacggacagt ccatatgaag cgattaagcc
     3241 cgctgaaaaa caggaaacgt atccggtttc ctctgcccaa aagcggattt atgtccttca
     3301 gcagctggag gacggaggga caggctacaa tatgccagct gtgttagagc tcgaagggaa
     3361 gctcaaccct gaaaggatgg acagagcttt caaagagctg atcaagcgcc acgagtcgct
     3421 tcggacctcc ttcgaacagg acgcaggagg cgatccggtg cagcgcatcc atgacgaggt
     3481 gccgtttacg ttacagacta cagttctcgg cgaacgaacc gaagaggagg ccgcagccgc
     3541 atttatcaaa ccgtttgatc tcagccaagc gccgctgttc cgtgcccaaa tcgtaaaggt
     3601 atcagatgag cggcacctgt tgctggtgga tatgcatcac atcatttcag acggtgtttc
     3661 cgtcaaca
//
