## Fri May 2 15:03:57 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_023520855.1/GCA_023520855.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_023520855.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_023520855.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs HPHIIJEP_00001 224308.BSU18410 0.0 1170.0 COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus 91061|Bacilli E gamma-glutamyltransferase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept HPHIIJEP_00002 224308.BSU18400 3.31e-47 151.0 COG0166@1|root,COG0166@2|Bacteria,1VFQ2@1239|Firmicutes,4HNRS@91061|Bacilli,1ZIWJ@1386|Bacillus 91061|Bacilli G Helix-turn-helix domain yoeD - - - - - - - - - - - HTH_17 HPHIIJEP_00003 224308.BSU18390 1.14e-124 355.0 COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,4HE06@91061|Bacilli,1ZGYW@1386|Bacillus 91061|Bacilli L Integrase - - - - - - - - - - - - Phage_integrase HPHIIJEP_00005 1348908.KI518589_gene2572 2.16e-152 441.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,1ZFHI@1386|Bacillus 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase HPHIIJEP_00009 1178540.BA70_18640 9.59e-50 162.0 COG1396@1|root,COG1396@2|Bacteria,1UV6T@1239|Firmicutes,4I1D1@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 HPHIIJEP_00010 748247.AZKH_1637 1.79e-09 57.8 COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria 1224|Proteobacteria K PFAM helix-turn-helix domain protein ahdIC - - - - - - - - - - - HTH_3 HPHIIJEP_00011 1348908.KI518589_gene2568 2.95e-51 164.0 COG4707@1|root,COG4707@2|Bacteria,1VDBG@1239|Firmicutes,4HKZG@91061|Bacilli,1ZHEE@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF771) - - - - - - - - - - - - DUF771 HPHIIJEP_00013 1178540.BA70_18625 9e-119 349.0 COG3935@1|root,COG3935@2|Bacteria,1TSHD@1239|Firmicutes,4HIGY@91061|Bacilli,1ZCUE@1386|Bacillus 91061|Bacilli L Conserved phage C-terminus (Phg_2220_C) - - - - - - - - - - - - Phage_rep_org_N,Phg_2220_C HPHIIJEP_00014 1033740.CAEW01000026_gene511 3.96e-21 97.8 COG1484@1|root,COG1484@2|Bacteria,1V36Z@1239|Firmicutes,4HG44@91061|Bacilli,26HY1@186818|Planococcaceae 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 HPHIIJEP_00016 649747.HMPREF0083_01033 3.7e-09 58.5 2EH6G@1|root,33AYC@2|Bacteria,1VMIH@1239|Firmicutes,4HRRB@91061|Bacilli,271A0@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00019 1444310.JANV01000004_gene2692 4.65e-08 50.8 29TKI@1|root,30ETZ@2|Bacteria,1UCYU@1239|Firmicutes,4IPES@91061|Bacilli,1ZPTG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00022 226185.EF_1440 7.58e-10 60.5 2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,4HR69@91061|Bacilli,4B4BD@81852|Enterococcaceae 91061|Bacilli S YopX protein - - - - - - - - - - - - YopX HPHIIJEP_00024 315750.BPUM_2110 1.78e-06 49.3 29T3H@1|root,30EA2@2|Bacteria,1UCAX@1239|Firmicutes,4INTC@91061|Bacilli,1ZNXC@1386|Bacillus 91061|Bacilli S Bacillus cereus group antimicrobial protein - - - - - - - - - - - - lci HPHIIJEP_00025 358681.BBR47_35510 7.2e-66 224.0 COG1196@1|root,COG1196@2|Bacteria,1TSP6@1239|Firmicutes,4HYT3@91061|Bacilli,2709K@186822|Paenibacillaceae 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - - HPHIIJEP_00026 1178540.BA70_18520 1.2e-64 201.0 COG0677@1|root,COG0677@2|Bacteria,1VPRK@1239|Firmicutes,4HSME@91061|Bacilli,1ZI90@1386|Bacillus 91061|Bacilli M ArpU family transcriptional regulator - - - - - - - - - - - - - HPHIIJEP_00027 171693.BN988_01616 1.99e-76 232.0 COG0582@1|root,COG0582@2|Bacteria,1V3HC@1239|Firmicutes,4IS1M@91061|Bacilli 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase HPHIIJEP_00028 292564.Cyagr_1943 1.17e-28 118.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - - HPHIIJEP_00029 160488.PP_3067 1.33e-07 60.1 COG1196@1|root,COG1196@2|Bacteria,1Q0BF@1224|Proteobacteria,1TMB7@1236|Gammaproteobacteria,1YZCX@136845|Pseudomonas putida group 1236|Gammaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - HPHIIJEP_00031 720555.BATR1942_07725 4.5e-59 194.0 2A08E@1|root,30NBN@2|Bacteria,1UAQU@1239|Firmicutes,4IM3F@91061|Bacilli,1ZJ0T@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00032 10717.Q38456_BPPH1 8.16e-77 229.0 4QAKE@10239|Viruses,4QUP7@35237|dsDNA viruses no RNA stage,4QPCE@28883|Caudovirales,4QKTX@10699|Siphoviridae 10699|Siphoviridae S HNH endonuclease - - - - - - - - - - - - - HPHIIJEP_00033 1178540.BA70_20040 9.33e-27 102.0 2ENM5@1|root,33G8I@2|Bacteria,1VKP5@1239|Firmicutes,4HREM@91061|Bacilli,1ZP0S@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00034 10717.Q9ZXG2_BPPH1 1.42e-89 266.0 4QBS6@10239|Viruses,4QUNW@35237|dsDNA viruses no RNA stage,4QPP2@28883|Caudovirales,4QM0S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase, small subunit - - - - - - - - - - - - - HPHIIJEP_00035 10717.Q9ZXG1_BPPH1 1.02e-279 773.0 4QBV3@10239|Viruses,4QW0W@35237|dsDNA viruses no RNA stage,4QPPJ@28883|Caudovirales,4QKW5@10699|Siphoviridae 10699|Siphoviridae S Phage Terminase - - - - - - - - - - - - - HPHIIJEP_00036 66692.ABC1330 5.41e-14 67.0 29T9N@1|root,30EGM@2|Bacteria,1UCIM@1239|Firmicutes,4IP0S@91061|Bacilli,1ZP7Q@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00037 10717.Q9ZXF8_BPPH1 3.21e-271 745.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - HPHIIJEP_00038 10717.Q9ZXF7_BPPH1 3.81e-134 381.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0003674,GO:0003824,GO:0005575,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019012,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - - HPHIIJEP_00039 1178540.BA70_16580 8.85e-230 639.0 COG4653@1|root,COG4653@2|Bacteria,1UACS@1239|Firmicutes,4HEAS@91061|Bacilli,1ZDKB@1386|Bacillus 91061|Bacilli S capsid protein - - - - - - - - - - - - Phage_capsid HPHIIJEP_00040 1274524.BSONL12_21399 7.93e-09 56.6 29NR5@1|root,309P3@2|Bacteria,1UCJS@1239|Firmicutes,4IP1X@91061|Bacilli,1ZP9D@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - Collagen HPHIIJEP_00041 10717.Q9ZXF4_BPPH1 1.73e-38 136.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - HPHIIJEP_00042 1178540.BA70_16530 4.7e-35 123.0 28TB1@1|root,2ZFJJ@2|Bacteria,1VGRD@1239|Firmicutes,4HS56@91061|Bacilli,1ZK55@1386|Bacillus 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 HPHIIJEP_00043 1178540.BA70_17630 1.32e-63 196.0 2DP09@1|root,3300D@2|Bacteria,1VHDB@1239|Firmicutes,4HPMI@91061|Bacilli,1ZK56@1386|Bacillus 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like HPHIIJEP_00044 1178540.BA70_16555 1.65e-39 135.0 29SR2@1|root,30DWY@2|Bacteria,1UBUP@1239|Firmicutes,4INA6@91061|Bacilli,1ZN4K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3168 HPHIIJEP_00045 235909.GK0536 9.75e-79 240.0 28J9R@1|root,2Z94K@2|Bacteria,1VV8I@1239|Firmicutes,4IRCP@91061|Bacilli,1WHY7@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00046 574376.BAMA_22710 6.03e-36 125.0 2DW9V@1|root,33Z7W@2|Bacteria,1VXVY@1239|Firmicutes,4HX4J@91061|Bacilli 574376.BAMA_22710|- - - - - - - - - - - - - - - - HPHIIJEP_00047 235909.GK0538 1e-16 72.8 2C4HK@1|root,2ZW6A@2|Bacteria,1W5ZZ@1239|Firmicutes,4IFPP@91061|Bacilli,1WHPM@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00048 10717.Q9ZXE7_BPPH1 0.0 1390.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - HPHIIJEP_00049 279010.BL03514 5.91e-143 409.0 2E9AZ@1|root,333IU@2|Bacteria,1VGQF@1239|Firmicutes,4HQBT@91061|Bacilli,1ZH89@1386|Bacillus 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail HPHIIJEP_00050 1274524.BSONL12_06183 2.3e-307 850.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIVW@91061|Bacilli,1ZGF4@1386|Bacillus 91061|Bacilli NU Prophage endopeptidase tail acm2 - 3.2.1.17 ko:K01185 - - - - ko00000,ko01000 - - - Glucosaminidase,Prophage_tail,SH3_5 HPHIIJEP_00051 1246626.BleG1_2994 3.61e-62 219.0 2ENW5@1|root,33GH6@2|Bacteria,1VPJ7@1239|Firmicutes,4HSTH@91061|Bacilli,1ZJCY@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00054 224308.BSU21250 3.44e-78 258.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,4HS4X@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - Phage_fiber_2 HPHIIJEP_00057 224308.BSU21420 6.31e-38 127.0 2EE5S@1|root,2ZUAI@2|Bacteria,1W1UA@1239|Firmicutes,4I0TR@91061|Bacilli,1ZJC2@1386|Bacillus 91061|Bacilli S BhlA holin family bhlA - - - - - - - - - - - Holin_BhlA HPHIIJEP_00058 1051501.AYTL01000027_gene861 1.3e-40 135.0 2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,4HP5W@91061|Bacilli,1ZKKG@1386|Bacillus 91061|Bacilli S SPP1 phage holin xhlB - - - - - - - - - - - Holin_SPP1 HPHIIJEP_00059 1274524.BSONL12_13191 2.33e-160 457.0 COG1388@1|root,COG3409@1|root,COG5632@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,COG5632@2|Bacteria,1V5B9@1239|Firmicutes,4HJY4@91061|Bacilli,1ZIM6@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase xlyB - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,LysM,PG_binding_1 HPHIIJEP_00061 1274524.BSONL12_10321 4.68e-53 167.0 2CHB8@1|root,33P7C@2|Bacteria,1VQE4@1239|Firmicutes,4HZA2@91061|Bacilli,1ZKQZ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00062 1274524.BSONL12_10326 2.62e-245 693.0 COG5444@1|root,COG5444@2|Bacteria,1VDC1@1239|Firmicutes,4HQE1@91061|Bacilli,1ZQPE@1386|Bacillus 91061|Bacilli A Pre-toxin TG - - - ko:K21491 - - - - ko00000,ko01000,ko02048 - - - GH-E,LXG,PT-TG HPHIIJEP_00065 224308.BSU18380 7.14e-128 363.0 2DQ89@1|root,33587@2|Bacteria,1VHBN@1239|Firmicutes,4HP4B@91061|Bacilli,1ZH85@1386|Bacillus 91061|Bacilli S IseA DL-endopeptidase inhibitor yoeB - - - - - - - - - - - Endopep_inhib HPHIIJEP_00066 224308.BSU18370 9.8e-313 854.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,1ZEAW@1386|Bacillus 91061|Bacilli V MATE efflux family protein yoeA - - - - - - - - - - - MatE HPHIIJEP_00067 224308.BSU18360 2.25e-239 657.0 COG2017@1|root,COG2017@2|Bacteria,1TS6R@1239|Firmicutes,4IRTK@91061|Bacilli,1ZGMA@1386|Bacillus 91061|Bacilli G Aldose 1-epimerase yoxA GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim HPHIIJEP_00068 224308.BSU18350 0.0 937.0 COG2027@1|root,COG2027@2|Bacteria,1TQFQ@1239|Firmicutes,4HA3X@91061|Bacilli,1ZBNY@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase dacC - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 HPHIIJEP_00069 224308.BSU18340 0.0 5000.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_00070 224308.BSU18330 0.0 4996.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - ko:K15665 ko01054,map01054 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_00071 224308.BSU18320 0.0 4875.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_00072 224308.BSU18310 0.0 7032.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_00073 224308.BSU18300 0.0 2480.0 COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria 2|Bacteria Q amino acid activation for nonribosomal peptide biosynthetic process - - 6.3.2.14 ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,KR,PP-binding,Thioesterase HPHIIJEP_00074 224308.BSU18290 2.04e-82 244.0 2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HQ6D@91061|Bacilli,1ZGTF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1360) yngL - - - - - - - - - - - DUF1360 HPHIIJEP_00075 224308.BSU18280 0.0 1044.0 COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,1ZC0H@1386|Bacillus 91061|Bacilli T Glycosyl hydrolase-like 10 yngK - - - - - - - - - - - Big_2,Cu_amine_oxidN1,GHL10 HPHIIJEP_00076 224308.BSU18260 3.09e-267 732.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1ZCGC@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase yngJ - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HPHIIJEP_00077 224308.BSU18250 0.0 1102.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HAHB@91061|Bacilli,1ZPZR@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II yngI - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C HPHIIJEP_00078 224308.BSU18240 9.36e-317 863.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZBTG@1386|Bacillus 91061|Bacilli I Biotin carboxylase yngH - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 HPHIIJEP_00079 224308.BSU18239 7.15e-43 140.0 COG0511@1|root,COG0511@2|Bacteria,1UI6N@1239|Firmicutes,4ISFM@91061|Bacilli,1ZIUY@1386|Bacillus 91061|Bacilli I Biotin carboxyl carrier protein - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl HPHIIJEP_00080 224308.BSU18230 7.86e-211 583.0 COG0119@1|root,COG0119@2|Bacteria,1TQG3@1239|Firmicutes,4HA1U@91061|Bacilli,1ZC18@1386|Bacillus 91061|Bacilli E Hydroxymethylglutaryl-CoA lyase yngG GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like HPHIIJEP_00081 224308.BSU18220 7.04e-174 486.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,1ZAXG@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family yngF GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - - - - - - - - - - ECH_1 HPHIIJEP_00082 224308.BSU18210 0.0 992.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1ZBHM@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yngE - - - - - - - - - - iYO844.BSU18210 Carboxyl_trans HPHIIJEP_00083 224308.BSU18200 7.39e-296 806.0 COG2404@1|root,COG2404@2|Bacteria,1TQPZ@1239|Firmicutes,4HCSM@91061|Bacilli,1ZCH8@1386|Bacillus 91061|Bacilli S phosphohydrolase (DHH superfamily) yngD - - ko:K07097 - - - - ko00000 - - - DHHA1 HPHIIJEP_00084 224308.BSU18190 2.01e-134 381.0 COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli,1ZCPB@1386|Bacillus 91061|Bacilli S membrane-associated protein yngC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc HPHIIJEP_00085 224308.BSU18180 1.12e-209 580.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase yngB - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase HPHIIJEP_00086 224308.BSU18170 1.72e-103 299.0 COG2246@1|root,COG2246@2|Bacteria,1VCBC@1239|Firmicutes,4HM7K@91061|Bacilli,1ZRYB@1386|Bacillus 91061|Bacilli S membrane yngA - - - - - - - - - - - GtrA HPHIIJEP_00087 224308.BSU18160 0.0 1006.0 COG3507@1|root,COG3507@2|Bacteria,1TSKZ@1239|Firmicutes,4HTDV@91061|Bacilli,1ZATA@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 43 family xynD GO:0005575,GO:0005576 3.2.1.55 ko:K15921 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - CBM6,GH43 - CBM_6,Glyco_hydro_43 HPHIIJEP_00088 224308.BSU18150 9.85e-317 860.0 COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,4HS8Y@91061|Bacilli 91061|Bacilli M Belongs to the glycosyl hydrolase 30 family ynfF GO:0003674,GO:0003824,GO:0016787 3.2.1.136 ko:K15924 - - - - ko00000,ko01000 - GH5 - CBM_6,Glyco_hydro_30,Glyco_hydro_30C HPHIIJEP_00090 224308.BSU18130 0.0 1012.0 COG2730@1|root,COG2730@2|Bacteria,1TSJQ@1239|Firmicutes,4HFEH@91061|Bacilli,1ZEYQ@1386|Bacillus 91061|Bacilli G PFAM glycoside hydrolase family 5 bglC5 - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_3,Cellulase HPHIIJEP_00091 224308.BSU18120 0.0 873.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter alsT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp HPHIIJEP_00092 224308.BSU18110 2.5e-74 223.0 29KWY@1|root,307UE@2|Bacteria,1U284@1239|Firmicutes,4IBSD@91061|Bacilli,1ZHFJ@1386|Bacillus 91061|Bacilli - - ynfC - - - - - - - - - - - - HPHIIJEP_00093 326423.RBAM_017920 1.82e-18 76.3 29SDG@1|root,30DI8@2|Bacteria,1UBB9@1239|Firmicutes,4IMQ6@91061|Bacilli,1ZKKQ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00094 224308.BSU18100 0.0 1578.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,1ZBCI@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV HPHIIJEP_00095 224308.BSU18090 0.0 1270.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,1ZBMM@1386|Bacillus 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HPHIIJEP_00096 224308.BSU18080 1.21e-90 265.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli,1ZG6W@1386|Bacillus 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 HPHIIJEP_00097 224308.BSU18070 5.48e-122 349.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,1ZFP9@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf HPHIIJEP_00098 224308.BSU18060 8.97e-65 197.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,1ZHU4@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn HPHIIJEP_00099 224308.BSU18050 4.68e-71 213.0 2CICC@1|root,32S7S@2|Bacteria,1VC46@1239|Firmicutes,4HKPJ@91061|Bacilli,1ZI00@1386|Bacillus 91061|Bacilli - - yneQ - - - - - - - - - - - - HPHIIJEP_00100 1051501.AYTL01000033_gene272 4.02e-95 277.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,1ZQR3@1386|Bacillus 91061|Bacilli S Thioesterase-like superfamily yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 HPHIIJEP_00101 224308.BSU18030 6.62e-48 153.0 2E62M@1|root,330RR@2|Bacteria,1VF8M@1239|Firmicutes,4HPWY@91061|Bacilli,1ZITR@1386|Bacillus 91061|Bacilli S Belongs to the Tlp family tlp - - ko:K06434 - - - - ko00000 - - - - HPHIIJEP_00103 1178537.BA1_08746 3.22e-10 55.5 29SCZ@1|root,30DHM@2|Bacteria,1UBAQ@1239|Firmicutes,4IMPJ@91061|Bacilli,1ZKJ9@1386|Bacillus 91061|Bacilli S Fur-regulated basic protein B - - - - - - - - - - - - Fur_reg_FbpB HPHIIJEP_00104 224308.BSU18010 1.46e-117 336.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus 91061|Bacilli CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen yneN - - - - - - - - - - - AhpC-TSA HPHIIJEP_00105 224308.BSU18000 0.0 1815.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,1ZART@1386|Bacillus 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate citB GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06730 Aconitase,Aconitase_C HPHIIJEP_00106 1178537.BA1_08761 3.75e-21 83.6 2EI8E@1|root,33BZS@2|Bacteria,1VNNB@1239|Firmicutes,4HS1A@91061|Bacilli,1ZIU1@1386|Bacillus 91061|Bacilli S Belongs to the SspO family sspO - - ko:K06432 - - - - ko00000 - - - SspO HPHIIJEP_00107 224308.BSU17980 5.65e-27 98.2 2E54C@1|root,32ZXB@2|Bacteria,1VJFQ@1239|Firmicutes,4HQN1@91061|Bacilli,1ZK01@1386|Bacillus 91061|Bacilli S Belongs to the SspP family sspP - - ko:K06433 - - - - ko00000 - - - SspP HPHIIJEP_00108 224308.BSU17970 2.35e-84 249.0 COG0071@1|root,COG0071@2|Bacteria,1UB14@1239|Firmicutes,4IME0@91061|Bacilli,1ZJX9@1386|Bacillus 91061|Bacilli O Spore coat protein cotM - - ko:K06335 - - - - ko00000 - - - - HPHIIJEP_00109 224308.BSU17960 2.79e-97 283.0 291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2621) yneK - - - - - - - - - - - DUF2621 HPHIIJEP_00110 224308.BSU17950 2.51e-98 287.0 COG4846@1|root,COG4846@2|Bacteria,1V7C6@1239|Firmicutes,4HGXI@91061|Bacilli,1ZG68@1386|Bacillus 91061|Bacilli O COG4846 Membrane protein involved in cytochrome C biogenesis yneJ - - - - - - - - - - - DUF1453 HPHIIJEP_00111 224308.BSU17940 2.12e-77 231.0 COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4ISX0@91061|Bacilli,1ZRES@1386|Bacillus 91061|Bacilli T cheY-homologous receiver domain ccdB - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg HPHIIJEP_00112 224308.BSU17930 4.13e-165 462.0 COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus 91061|Bacilli O cytochrome c biogenesis protein ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD HPHIIJEP_00113 326423.RBAM_017720 4.59e-21 84.0 29S1R@1|root,30D66@2|Bacteria,1UAWP@1239|Firmicutes,4IM9H@91061|Bacilli,1ZJIT@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein ynzD - - - - - - - - - - - SpoOE-like HPHIIJEP_00114 1051501.AYTL01000033_gene259 4.36e-39 130.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,1ZHYQ@1386|Bacillus 91061|Bacilli S UPF0154 protein yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 HPHIIJEP_00115 224308.BSU17900 2.18e-106 306.0 2EUDS@1|root,33MW4@2|Bacteria,1VHIA@1239|Firmicutes,4HSFG@91061|Bacilli,1ZEP8@1386|Bacillus 91061|Bacilli S Sporulation inhibitor of replication protein sirA yneE - - - - - - - - - - - SirA HPHIIJEP_00116 224308.BSU17890 0.0 1310.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli,1ZBQ6@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N HPHIIJEP_00117 224308.BSU17880 1.15e-43 142.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,1ZIU8@1386|Bacillus 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 HPHIIJEP_00118 224308.BSU17870 2.29e-144 408.0 COG1961@1|root,COG1961@2|Bacteria,1TR74@1239|Firmicutes,4HBJI@91061|Bacilli,1ZCET@1386|Bacillus 91061|Bacilli L resolvase yneB GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - - - - - - - - - - Resolvase HPHIIJEP_00119 224308.BSU17860 8.5e-65 197.0 COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,4HRE2@91061|Bacilli,1ZH8B@1386|Bacillus 91061|Bacilli D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery yneA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - - - - - - - - - - LysM HPHIIJEP_00120 224308.BSU17850 7.22e-142 400.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,1ZBMU@1386|Bacillus 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 HPHIIJEP_00122 224308.BSU17840 6.24e-96 279.0 COG0346@1|root,COG0346@2|Bacteria,1V422@1239|Firmicutes,4HH25@91061|Bacilli,1ZG9A@1386|Bacillus 91061|Bacilli H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor fosB GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 - ko:K11210,ko:K21252 - - - - ko00000,ko01000,ko01504 - - - Glyoxalase HPHIIJEP_00123 224308.BSU17830 3.79e-96 281.0 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,1ZINT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2512) yndM - - - - - - - - - - - DUF2512 HPHIIJEP_00124 224308.BSU17820 9.34e-175 488.0 COG4195@1|root,COG4195@2|Bacteria,1VBQ5@1239|Firmicutes,4HK5Q@91061|Bacilli,1ZECB@1386|Bacillus 91061|Bacilli S Replication protein yndL - - - - - - - - - - - Gamma_PGA_hydro HPHIIJEP_00126 224308.BSU17800 0.0 1041.0 28KUD@1|root,2ZAB6@2|Bacteria,1TRII@1239|Firmicutes,4HA8V@91061|Bacilli,1ZCE4@1386|Bacillus 91061|Bacilli S YndJ-like protein yndJ - - - - - - - - - - - YndJ HPHIIJEP_00127 224308.BSU17790 1.71e-149 420.0 arCOG11972@1|root,2ZG4P@2|Bacteria,1V2DB@1239|Firmicutes,4HGUW@91061|Bacilli,1ZGP4@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4166) - - - - - - - - - - - - DUF4166 HPHIIJEP_00128 224308.BSU17780 2.94e-195 541.0 29RNN@1|root,30CRY@2|Bacteria,1UP6P@1239|Firmicutes,4HBII@91061|Bacilli,1ZF3C@1386|Bacillus 91061|Bacilli S DoxX-like family yndG - - - - - - - - - - - DoxX_3 HPHIIJEP_00129 224308.BSU17770 4.58e-288 787.0 28IEM@1|root,2Z8GN@2|Bacteria,1UB3Y@1239|Firmicutes,4HV0B@91061|Bacilli,1ZRWJ@1386|Bacillus 91061|Bacilli S Spore germination protein - - - ko:K06293,ko:K06312 - - - - ko00000 - - - Spore_GerAC HPHIIJEP_00130 224308.BSU17760 5.35e-248 682.0 COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,4ISWZ@91061|Bacilli,1ZS7K@1386|Bacillus 91061|Bacilli U Spore germination yndE7 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K06311 - - - - ko00000,ko02000 2.A.3.9.4 - - Spore_permease HPHIIJEP_00131 224308.BSU17750 0.0 985.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein yndD1 - - ko:K06288,ko:K06291,ko:K06310 - - - - ko00000 - - - GerA HPHIIJEP_00134 224308.BSU17730 1.81e-103 298.0 COG3832@1|root,COG3832@2|Bacteria,1V7US@1239|Firmicutes,4HK0E@91061|Bacilli,1ZGHK@1386|Bacillus 91061|Bacilli S Activator of Hsp90 ATPase homolog 1-like protein yndB - - - - - - - - - - - AHSA1 HPHIIJEP_00135 224308.BSU17720 8.58e-94 273.0 2BAHV@1|root,323YG@2|Bacteria,1U0CE@1239|Firmicutes,4I9P8@91061|Bacilli,1ZKHR@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00136 224308.BSU17710 2.37e-34 117.0 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA - - ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02000,ko02044 2.A.64,2.C.1.2 - - MttA_Hcf106 HPHIIJEP_00139 224308.BSU17690 1.22e-169 474.0 2CQ69@1|root,32SKI@2|Bacteria,1VCJR@1239|Firmicutes,4HNF9@91061|Bacilli,1ZFBY@1386|Bacillus 91061|Bacilli S Domain of unknown function, YrpD - - - - - - - - - - - - YrpD HPHIIJEP_00141 10736.A0A1P8CX42_BPPHT 2.75e-210 580.0 4QBA2@10239|Viruses,4QV98@35237|dsDNA viruses no RNA stage,4QPPI@28883|Caudovirales,4QM0B@10699|Siphoviridae 10699|Siphoviridae S Thymidylate synthase - GO:0003674,GO:0003824,GO:0004799,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0042083 - - - - - - - - - - - HPHIIJEP_00144 224308.BSU17660 3.51e-101 293.0 COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,4HHFX@91061|Bacilli,1ZGRC@1386|Bacillus 91061|Bacilli F Deoxyuridine 5'-triphosphate yncF GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17660 dUTPase HPHIIJEP_00145 224308.BSU17650 5.49e-107 308.0 2CEK2@1|root,32S02@2|Bacteria,1VCYR@1239|Firmicutes,4HXMN@91061|Bacilli,1ZR51@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2691) - - - - - - - - - - - - DUF2691 HPHIIJEP_00146 224308.BSU17640 1.02e-279 765.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N HPHIIJEP_00147 224308.BSU17630 0.0 883.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,1ZAUM@1386|Bacillus 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.26 - - Sugar_tr HPHIIJEP_00148 224308.BSU17620 6.15e-146 411.0 COG1525@1|root,COG1525@2|Bacteria,1V46V@1239|Firmicutes,4HHJ1@91061|Bacilli,1ZQ6S@1386|Bacillus 91061|Bacilli L RNA catabolic process yokF GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - Excalibur,SNase HPHIIJEP_00149 224308.BSU17610 0.0 999.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4HBRJ@91061|Bacilli,1ZBEJ@1386|Bacillus 91061|Bacilli G xylulose kinase xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU17610 FGGY_C,FGGY_N HPHIIJEP_00150 224308.BSU17600 0.0 904.0 COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,4H9WG@91061|Bacilli,1ZE2B@1386|Bacillus 91061|Bacilli G Belongs to the xylose isomerase family xylA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 HPHIIJEP_00151 224308.BSU17590 8.3e-274 749.0 COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,1ZC4Y@1386|Bacillus 91061|Bacilli GK ROK family xylR - - - - - - - - - - - HTH_24,ROK HPHIIJEP_00152 224308.BSU17580 0.0 1127.0 COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,1ZCCV@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 43 family xynB - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - DUF1349,Glyco_hydro_43 HPHIIJEP_00153 224308.BSU17570 0.0 889.0 COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HENT@91061|Bacilli,1ZR5N@1386|Bacillus 91061|Bacilli G MFS/sugar transport protein xynP - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 HPHIIJEP_00154 224308.BSU17560 1.28e-102 297.0 COG0135@1|root,COG0135@2|Bacteria,1V436@1239|Firmicutes,4HIUW@91061|Bacilli,1ZFVR@1386|Bacillus 91061|Bacilli E phosphoribosylanthranilate isomerase activity - - - - - - - - - - - - - HPHIIJEP_00156 224308.BSU17540 8.24e-54 171.0 29SWA@1|root,30E2I@2|Bacteria,1UC1P@1239|Firmicutes,4INHS@91061|Bacilli,1ZNHQ@1386|Bacillus 91061|Bacilli - - ynaF - - - - - - - - - - - - HPHIIJEP_00157 224308.BSU17530 2.83e-87 260.0 2CHEV@1|root,2ZC9V@2|Bacteria,1V1ZK@1239|Firmicutes,4HGJX@91061|Bacilli,1ZE3N@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3885) - - - - - - - - - - - - DUF3885 HPHIIJEP_00158 224308.BSU20950 9.72e-31 109.0 COG3655@1|root,COG3655@2|Bacteria,1VJKD@1239|Firmicutes,4I010@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 HPHIIJEP_00159 326423.RBAM_034140 2.38e-11 63.9 2B1TR@1|root,31U9Q@2|Bacteria,1UCW8@1239|Firmicutes,4IPC8@91061|Bacilli,1ZPPX@1386|Bacillus 91061|Bacilli S Uncharacterised protein family (UPF0715) ywlA - - - - - - - - - - - UPF0715 HPHIIJEP_00160 1501230.ET33_35185 1.06e-91 281.0 COG1266@1|root,COG1266@2|Bacteria,1UMYH@1239|Firmicutes,4IU3B@91061|Bacilli,277HQ@186822|Paenibacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi HPHIIJEP_00161 224308.BSU17520 2.9e-126 358.0 COG1670@1|root,COG1670@2|Bacteria,1V5D0@1239|Firmicutes,4HFTD@91061|Bacilli,1ZFVB@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain ynaD - - - - - - - - - - - Acetyltransf_3 HPHIIJEP_00162 1051501.AYTL01000029_gene1648 3.14e-274 756.0 COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria,1UY4U@1239|Firmicutes,4HBMQ@91061|Bacilli,1ZENC@1386|Bacillus 91061|Bacilli H N-terminal domain of galactosyltransferase - - - - - - - - - - - - Glyco_transf_7C,Glycos_transf_2 HPHIIJEP_00163 1051501.AYTL01000029_gene1649 2.03e-246 678.0 COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,4H9X9@91061|Bacilli,1ZCYT@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2,TPR_8 HPHIIJEP_00164 1051501.AYTL01000029_gene1650 5.8e-156 439.0 COG2227@1|root,COG2227@2|Bacteria,1W0ME@1239|Firmicutes,4HQ1K@91061|Bacilli,1ZEK5@1386|Bacillus 91061|Bacilli H Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 HPHIIJEP_00165 1051501.AYTL01000029_gene1651 7.88e-119 342.0 COG1216@1|root,COG1216@2|Bacteria,1V5W3@1239|Firmicutes,4IS9R@91061|Bacilli,1ZFUU@1386|Bacillus 91061|Bacilli M Glycosyltransferase like family - - - - - - - - - - - - Glyco_tranf_2_5 HPHIIJEP_00168 586416.GZ22_07760 4.94e-13 66.6 2E5DI@1|root,3305I@2|Bacteria,1VJBB@1239|Firmicutes,4HQRW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00170 1051501.AYTL01000027_gene768 3.39e-309 858.0 COG5444@1|root,COG5444@2|Bacteria,1V674@1239|Firmicutes 1239|Firmicutes M nucleic acid phosphodiester bond hydrolysis - - - - - - - - - - - - EndoU_bacteria,Endonuclea_NS_2,LXG HPHIIJEP_00171 66692.ABC1062 2.3e-41 138.0 2BWJU@1|root,304V5@2|Bacteria,1TX8U@1239|Firmicutes,4IKVN@91061|Bacilli,1ZHWV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00172 1444310.JANV01000136_gene2568 1.05e-07 50.8 2BWJU@1|root,33F3X@2|Bacteria,1VKHV@1239|Firmicutes,4HSYN@91061|Bacilli,1ZIAN@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00173 224308.BSU17460 0.0 900.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,1ZBIQ@1386|Bacillus 91061|Bacilli E glutamine synthetase glnA GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N HPHIIJEP_00174 224308.BSU17450 4.05e-89 261.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,1ZH1F@1386|Bacillus 91061|Bacilli K transcriptional glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 HPHIIJEP_00175 224308.BSU17440 5.58e-309 841.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus 91061|Bacilli P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase HPHIIJEP_00176 224308.BSU17430 4.47e-294 803.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,1ZBT6@1386|Bacillus 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 HPHIIJEP_00177 224308.BSU17420 2.29e-226 624.0 COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,1ZBII@1386|Bacillus 91061|Bacilli O stage V sporulation protein K spoVK - - ko:K06413 - - - - ko00000 - - - AAA HPHIIJEP_00178 224308.BSU17410 3.32e-149 423.0 COG0860@1|root,COG0860@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SPOR HPHIIJEP_00179 224308.BSU17400 6.15e-139 393.0 COG4112@1|root,COG4112@2|Bacteria,1V7SZ@1239|Firmicutes,4IRNS@91061|Bacilli,1ZRW4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - NUDIX HPHIIJEP_00180 224308.BSU17390 1.65e-243 668.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,1ZBBM@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm HPHIIJEP_00181 224308.BSU17380 0.0 1392.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,1ZANT@1386|Bacillus 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN HPHIIJEP_00182 224308.BSU17370 5.01e-66 201.0 COG1780@1|root,COG1780@2|Bacteria,1V9T1@1239|Firmicutes,4HJ0M@91061|Bacilli,1ZIDV@1386|Bacillus 91061|Bacilli F Probably involved in ribonucleotide reductase function nrdI GO:0000166,GO:0003674,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0019538,GO:0032553,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI HPHIIJEP_00183 1274524.BSONL12_21669 1.2e-30 109.0 2BK5Y@1|root,32EJN@2|Bacteria,1UAJ9@1239|Firmicutes,4IKXT@91061|Bacilli,1ZI93@1386|Bacillus 91061|Bacilli - - ymzA - - - - - - - - - - - - HPHIIJEP_00184 326423.RBAM_017150 1.63e-31 112.0 29S7U@1|root,30DCB@2|Bacteria,1UB4T@1239|Firmicutes,4IMHD@91061|Bacilli,1ZK5R@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00185 1051501.AYTL01000027_gene1306 1.28e-45 147.0 COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HNN2@91061|Bacilli,1ZHYZ@1386|Bacillus 91061|Bacilli J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq - - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq HPHIIJEP_00186 224308.BSU17330 1.38e-223 616.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,1ZBX9@1386|Bacillus 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT HPHIIJEP_00187 224308.BSU17320 5.41e-76 228.0 2DXCY@1|root,344GQ@2|Bacteria,1VZDS@1239|Firmicutes,4HYN9@91061|Bacilli,1ZFZA@1386|Bacillus 91061|Bacilli S YmaF family ymaF - - - - - - - - - - - YmaF HPHIIJEP_00189 224308.BSU17300 2.02e-66 202.0 COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HM1T@91061|Bacilli,1ZHQQ@1386|Bacillus 91061|Bacilli P Small Multidrug Resistance protein ebrA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K11814 - M00710 - - ko00000,ko00002,ko02000 2.A.7.1.6 - - Multi_Drug_Res HPHIIJEP_00190 224308.BSU17290 1.57e-73 221.0 COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HNJX@91061|Bacilli,1ZHXE@1386|Bacillus 91061|Bacilli P COG2076 Membrane transporters of cations and cationic drugs ebrB GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03297,ko:K11814,ko:K11815 - M00710 - - ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.6 - - Multi_Drug_Res HPHIIJEP_00191 224308.BSU17280 5.98e-105 303.0 COG1764@1|root,COG1764@2|Bacteria,1V41Y@1239|Firmicutes,4HH9W@91061|Bacilli,1ZFXM@1386|Bacillus 91061|Bacilli O redox protein, regulator of disulfide bond formation ymaD - - - - - - - - - - - OsmC HPHIIJEP_00192 224308.BSU17270 3.96e-163 457.0 COG4195@1|root,COG4195@2|Bacteria,1VBQ5@1239|Firmicutes,4HK5Q@91061|Bacilli,1ZECB@1386|Bacillus 91061|Bacilli S Replication protein ymaC - - - - - - - - - - - Gamma_PGA_hydro HPHIIJEP_00194 224308.BSU17260 0.0 888.0 COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,4HAZA@91061|Bacilli,1ZAZK@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family aprX - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8 HPHIIJEP_00195 224308.BSU17250 1.48e-204 565.0 COG0491@1|root,COG0491@2|Bacteria,1TSM4@1239|Firmicutes,4HBZ2@91061|Bacilli,1ZDRZ@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B HPHIIJEP_00196 224308.BSU17240 8.03e-81 239.0 2DRIZ@1|root,33BZG@2|Bacteria,1VMJW@1239|Firmicutes,4HR8I@91061|Bacilli,1ZJQF@1386|Bacillus 91061|Bacilli - - ymzB - - - - - - - - - - - - HPHIIJEP_00197 224308.BSU17230 2.39e-295 805.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 cypA GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006629,GO:0006706,GO:0006707,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016042,GO:0016053,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016713,GO:0017144,GO:0018130,GO:0019752,GO:0020037,GO:0032787,GO:0034641,GO:0036199,GO:0042364,GO:0042440,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046148,GO:0046164,GO:0046394,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.46,1.14.15.13 ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 HPHIIJEP_00198 224308.BSU17220 0.0 4993.0 COG0236@1|root,COG2227@1|root,COG3319@1|root,COG3321@1|root,COG0236@2|Bacteria,COG2227@2|Bacteria,COG3319@2|Bacteria,COG3321@2|Bacteria,1VRGS@1239|Firmicutes,4HV13@91061|Bacilli 91061|Bacilli HQ Beta-ketoacyl synthase - - - ko:K13615 - - - - ko00000,ko01004,ko01008 - - - KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Thioesterase,ketoacyl-synt HPHIIJEP_00199 224308.BSU17210 0.0 10707.0 COG1020@1|root,COG1028@1|root,COG3321@1|root,COG4221@1|root,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1TPTH@1239|Firmicutes,4HTBC@91061|Bacilli,1ZS7J@1386|Bacillus 91061|Bacilli IQ polyketide synthase - - - ko:K13611,ko:K13613,ko:K13614 - - - - ko00000,ko01004,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HPHIIJEP_00200 224308.BSU17200 0.0 8367.0 COG0236@1|root,COG0451@1|root,COG1020@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG0451@2|Bacteria,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,4HTBC@91061|Bacilli,1ZS7J@1386|Bacillus 91061|Bacilli IQ polyketide synthase - - - ko:K13611,ko:K13613,ko:K13614 - - - - ko00000,ko01004,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HPHIIJEP_00201 224308.BSU17190 0.0 8833.0 COG0236@1|root,COG0300@1|root,COG3321@1|root,COG4221@1|root,COG0236@2|Bacteria,COG0300@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,1VU8Z@1239|Firmicutes,4HV19@91061|Bacilli,1ZD1S@1386|Bacillus 91061|Bacilli Q Polyketide synthase of type I - - - ko:K13612 - - - - ko00000,ko01004,ko01008 - - - AMP-binding,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NAD_binding_4,PP-binding,PS-DH,ketoacyl-synt HPHIIJEP_00202 224308.BSU17180 0.0 9840.0 COG0300@1|root,COG0318@1|root,COG1020@1|root,COG1028@1|root,COG3321@1|root,COG0300@2|Bacteria,COG0318@2|Bacteria,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,4HTBC@91061|Bacilli,1ZS7J@1386|Bacillus 91061|Bacilli IQ polyketide synthase - - - ko:K13611,ko:K13613,ko:K13614 - - - - ko00000,ko01004,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HPHIIJEP_00203 224308.BSU17170 4.47e-176 491.0 COG1024@1|root,COG1024@2|Bacteria,1UY7Y@1239|Firmicutes,4HU35@91061|Bacilli 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family pksI GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - ko:K15313 - - - - ko00000,ko01008 - - - ECH_1 HPHIIJEP_00204 224308.BSU17160 2.78e-181 504.0 COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus 91061|Bacilli I enoyl-CoA hydratase - - - ko:K15312 - - - - ko00000,ko01008 - - - ECH_1 HPHIIJEP_00205 224308.BSU17150 4.61e-312 849.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,1ZE86@1386|Bacillus 91061|Bacilli I synthase pksG - 2.3.3.10 ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000,ko01008 - - - HMG_CoA_synt_C,HMG_CoA_synt_N HPHIIJEP_00206 224308.BSU17140 1.07e-303 827.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Ketoacyl-synt_C,ketoacyl-synt HPHIIJEP_00207 224308.BSU17130 5.46e-51 161.0 COG0236@1|root,COG0236@2|Bacteria,1VH6X@1239|Firmicutes,4HQ20@91061|Bacilli,1ZP8M@1386|Bacillus 91061|Bacilli IQ Phosphopantetheine attachment site acpK - - ko:K15337 - - - - ko00000,ko01008 - - - PP-binding HPHIIJEP_00208 224308.BSU17120 0.0 1505.0 COG0331@1|root,COG2070@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 HPHIIJEP_00209 224308.BSU17110 1.44e-230 635.0 COG3321@1|root,COG3321@2|Bacteria,1TRPC@1239|Firmicutes,4HGJQ@91061|Bacilli,1ZIAR@1386|Bacillus 91061|Bacilli Q Acyl transferase domain pksD - - ko:K15328 - - - - ko00000,ko01008 - - - Acyl_transf_1 HPHIIJEP_00211 224308.BSU17100 1.25e-206 571.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 HPHIIJEP_00212 224308.BSU17090 3.3e-166 464.0 COG0491@1|root,COG0491@2|Bacteria,1V5TI@1239|Firmicutes,4HH95@91061|Bacilli 91061|Bacilli S Polyketide biosynthesis pksB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B HPHIIJEP_00213 224308.BSU17080 9.85e-140 395.0 COG3226@1|root,COG3226@2|Bacteria,1V50H@1239|Firmicutes,4HJQ2@91061|Bacilli,1ZGDV@1386|Bacillus 91061|Bacilli K Transcriptional regulator pksA GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_C_6,TetR_N HPHIIJEP_00214 224308.BSU17070 1.54e-124 355.0 28NRE@1|root,2ZBQP@2|Bacteria,1V2C0@1239|Firmicutes,4HGF6@91061|Bacilli,1ZFQD@1386|Bacillus 91061|Bacilli S Membrane ymcC - - - - - - - - - - - - HPHIIJEP_00216 224308.BSU17060 1.91e-91 269.0 2E08D@1|root,32VW3@2|Bacteria,1VBA4@1239|Firmicutes,4HKHV@91061|Bacilli,1ZIVG@1386|Bacillus 91061|Bacilli S Regulatory protein YrvL - - - - - - - - - - - - YrvL HPHIIJEP_00217 224308.BSU17050 0.0 1192.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,1ZB9X@1386|Bacillus 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C HPHIIJEP_00218 224308.BSU17040 0.0 1661.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,1ZB93@1386|Bacillus 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V HPHIIJEP_00219 1051501.AYTL01000027_gene1290 1.74e-119 342.0 2BYGR@1|root,2ZIKA@2|Bacteria,1V30V@1239|Firmicutes,4HFX6@91061|Bacilli,1ZE20@1386|Bacillus 91061|Bacilli S Spore coat protein cotE GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06328 - - - - ko00000 - - - CotE HPHIIJEP_00220 224308.BSU17020 1.27e-89 263.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli,1ZG72@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF HPHIIJEP_00221 224308.BSU17010 0.0 1013.0 COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,4HAAS@91061|Bacilli,1ZBMF@1386|Bacillus 91061|Bacilli J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 HPHIIJEP_00222 224308.BSU17000 2.4e-277 759.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_00223 224308.BSU16990 8.31e-253 693.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,1ZPZV@1386|Bacillus 91061|Bacilli C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N HPHIIJEP_00224 1051501.AYTL01000027_gene1285 2.44e-49 157.0 COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,4HIQV@91061|Bacilli,1ZH05@1386|Bacillus 91061|Bacilli S Stage V sporulation protein S spoVS - - ko:K06416 - - - - ko00000 - - - SpoVS HPHIIJEP_00225 224308.BSU16970 6.18e-195 540.0 COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymdB GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - ko:K02029,ko:K02030,ko:K09769 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - YmdB HPHIIJEP_00226 224308.BSU16960 4.25e-306 842.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,1ZBGP@1386|Bacillus 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 HPHIIJEP_00227 224308.BSU16950 3.84e-278 761.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,1ZGWP@1386|Bacillus 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,Cu_amine_oxidN1 HPHIIJEP_00228 224308.BSU16940 2.72e-238 656.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,1ZCUX@1386|Bacillus 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA HPHIIJEP_00229 224308.BSU16930 1.06e-299 817.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,1ZC5R@1386|Bacillus 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth HPHIIJEP_00230 224308.BSU16920 3.34e-132 375.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,1ZBJ2@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf HPHIIJEP_00231 224308.BSU16910 8.75e-177 496.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,1ZDC1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 HPHIIJEP_00232 1051501.AYTL01000027_gene1276 3.91e-183 510.0 28HGR@1|root,2Z7SI@2|Bacteria,1TRXV@1239|Firmicutes,4HA2I@91061|Bacilli,1ZAU1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3388) ymfK - - - - - - - - - - - DUF3388 HPHIIJEP_00233 224308.BSU16880 5.13e-55 171.0 2E5KP@1|root,330BT@2|Bacteria,1VGM7@1239|Firmicutes,4HNNX@91061|Bacilli,1ZHTB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) ymfJ - - - - - - - - - - - DUF3243 HPHIIJEP_00234 224308.BSU16870 3.01e-166 465.0 COG0300@1|root,COG0300@2|Bacteria,1V5EI@1239|Firmicutes,4ISWY@91061|Bacilli,1ZS7I@1386|Bacillus 91061|Bacilli S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis ymfI - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HPHIIJEP_00235 224308.BSU16860 1.37e-308 841.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,1ZBXQ@1386|Bacillus 91061|Bacilli S zinc protease ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HPHIIJEP_00236 224308.BSU16845 1.1e-297 813.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,1ZCAJ@1386|Bacillus 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C HPHIIJEP_00237 224308.BSU16825 5.1e-266 731.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ymfD - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,MFS_2,Sugar_tr HPHIIJEP_00238 224308.BSU16810 1.28e-171 479.0 COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,4H9TG@91061|Bacilli,1ZB5M@1386|Bacillus 91061|Bacilli K Transcriptional regulator ymfC - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_00239 224308.BSU16800 0.0 1432.0 COG1674@1|root,COG4980@1|root,COG1674@2|Bacteria,COG4980@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,1ZANX@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma HPHIIJEP_00240 224308.BSU16799 4.94e-44 142.0 2DR6C@1|root,33ACS@2|Bacteria,1VM75@1239|Firmicutes,4IKY5@91061|Bacilli,1ZIB2@1386|Bacillus 91061|Bacilli S YlzJ-like protein - - - - - - - - - - - - YlzJ HPHIIJEP_00241 224308.BSU16790 5.01e-171 478.0 COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,4H9XG@91061|Bacilli,1ZBH5@1386|Bacillus 91061|Bacilli OU COG0740 Protease subunit of ATP-dependent Clp proteases tepA - - - - - - - - - - - CLP_protease HPHIIJEP_00242 224308.BSU16780 0.0 1066.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZB4E@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL HPHIIJEP_00243 224308.BSU16770 1.83e-200 556.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,1ZBNR@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS HPHIIJEP_00244 224308.BSU16760 4.9e-283 774.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZBSQ@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family dapG GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT_7 HPHIIJEP_00245 224308.BSU16750 2.36e-247 679.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,1ZAVS@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC HPHIIJEP_00246 224308.BSU16740 4.73e-140 395.0 COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,4HAU9@91061|Bacilli,1ZCJQ@1386|Bacillus 91061|Bacilli H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA) spoVFB - - ko:K06411 - - - - ko00000 - - iYO844.BSU16740 Flavoprotein HPHIIJEP_00247 224308.BSU16730 5.3e-208 575.0 COG1052@1|root,COG1052@2|Bacteria,1UI1W@1239|Firmicutes,4HA71@91061|Bacilli,1ZAZJ@1386|Bacillus 91061|Bacilli CH Dipicolinate synthase subunit A dpaA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K06410 - - - - ko00000 - - iYO844.BSU16730 2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N HPHIIJEP_00248 224308.BSU16720 1.53e-56 175.0 COG1873@1|root,COG1873@2|Bacteria,1VEJW@1239|Firmicutes,4HPFQ@91061|Bacilli,1ZI6Z@1386|Bacillus 91061|Bacilli S YlmC YmxH family ymxH - - - - - - - - - - - PRC HPHIIJEP_00249 224308.BSU16710 1.62e-295 806.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1ZDJE@1386|Bacillus 91061|Bacilli S Belongs to the peptidase M16 family mlpA - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HPHIIJEP_00250 224308.BSU16700 7.18e-233 640.0 COG0726@1|root,COG0726@2|Bacteria,1TQ5M@1239|Firmicutes,4HAHC@91061|Bacilli,1ZC6V@1386|Bacillus 91061|Bacilli G Sporulation protein, polysaccharide deacetylase ylxY GO:0005575,GO:0016020 - - - - - - - - - - Polysacc_deac_1 HPHIIJEP_00251 224308.BSU16690 0.0 1332.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,1ZB24@1386|Bacillus 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 HPHIIJEP_00252 224308.BSU16680 7.11e-57 176.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,1ZH7M@1386|Bacillus 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 HPHIIJEP_00253 224308.BSU16670 2.59e-229 631.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,1ZBFH@1386|Bacillus 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase HPHIIJEP_00254 224308.BSU16660 6.04e-220 607.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,1ZBKE@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N HPHIIJEP_00255 224308.BSU16650 3.29e-75 225.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,1ZGB3@1386|Bacillus 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA HPHIIJEP_00256 224308.BSU16640 1.11e-59 184.0 COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,4HNXC@91061|Bacilli,1ZI43@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxP - - ko:K09764 - - - - ko00000 - - - DUF503 HPHIIJEP_00257 224308.BSU16630 0.0 1047.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N HPHIIJEP_00258 224308.BSU16630 2.52e-51 179.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N HPHIIJEP_00259 224308.BSU16620 6.16e-63 192.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,1ZI1N@1386|Bacillus 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae HPHIIJEP_00260 224308.BSU16610 2.01e-57 178.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,1ZHSV@1386|Bacillus 91061|Bacilli K nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 HPHIIJEP_00261 224308.BSU16600 5.49e-261 716.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,1ZDAH@1386|Bacillus 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 HPHIIJEP_00262 224308.BSU16590 1.34e-104 302.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,1ZG6S@1386|Bacillus 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C HPHIIJEP_00263 224308.BSU16580 0.0 2850.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,1ZCIB@1386|Bacillus 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon HPHIIJEP_00264 224308.BSU16570 0.0 1108.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1ZD7M@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit HPHIIJEP_00265 224308.BSU16560 6.84e-294 803.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,1ZCPQ@1386|Bacillus 91061|Bacilli M zinc metalloprotease rasP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 HPHIIJEP_00266 224308.BSU16550 1.39e-276 756.0 COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus 91061|Bacilli I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom HPHIIJEP_00267 224308.BSU16540 5.77e-179 499.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,1ZBWF@1386|Bacillus 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 HPHIIJEP_00268 224308.BSU16530 3.84e-187 520.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,1ZC2T@1386|Bacillus 91061|Bacilli I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf HPHIIJEP_00269 224308.BSU16520 9.6e-119 340.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF HPHIIJEP_00270 224308.BSU16510 5.82e-163 457.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,1ZBMW@1386|Bacillus 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase HPHIIJEP_00271 224308.BSU16500 9.82e-202 559.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,1ZB7R@1386|Bacillus 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS HPHIIJEP_00272 224308.BSU16490 1.49e-168 471.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 HPHIIJEP_00273 224308.BSU16480 3.28e-99 290.0 2D5MU@1|root,32TJF@2|Bacteria,1V9ZA@1239|Firmicutes,4HMQI@91061|Bacilli,1ZF9N@1386|Bacillus 91061|Bacilli - - ylxL - - - - - - - - - - - - HPHIIJEP_00274 224308.BSU16470 3.8e-175 489.0 COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,4HCJV@91061|Bacilli,1ZAPF@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigD - - ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 - - - ko00000,ko00001,ko02035,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 HPHIIJEP_00275 224308.BSU16460 3.34e-112 322.0 COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,1ZGE3@1386|Bacillus 91061|Bacilli NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase cheD - 3.5.1.44 ko:K03411 ko02030,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheD HPHIIJEP_00276 224308.BSU16450 5.06e-144 406.0 COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,1ZDIE@1386|Bacillus 91061|Bacilli NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation cheC GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - ko:K03410 ko02030,map02030 - - - ko00000,ko00001,ko02035 - - - CheC,CheX HPHIIJEP_00277 224308.BSU16440 9.03e-103 298.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,4HHB5@91061|Bacilli,1ZGZE@1386|Bacillus 91061|Bacilli NT COG0835 Chemotaxis signal transduction protein cheW GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - CheW HPHIIJEP_00278 224308.BSU16430 0.0 1263.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,1ZATW@1386|Bacillus 91061|Bacilli NT COG0643 Chemotaxis protein histidine kinase and related kinases cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,P2 HPHIIJEP_00279 224308.BSU16420 7.38e-252 691.0 COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,4HBJY@91061|Bacilli,1ZC36@1386|Bacillus 91061|Bacilli NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR cheB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest,Response_reg HPHIIJEP_00280 224308.BSU16410 1.55e-200 556.0 COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,4HCWZ@91061|Bacilli,1ZE3G@1386|Bacillus 91061|Bacilli D Belongs to the ParA family ylxH - - ko:K04562 - - - - ko00000,ko02035 - - - AAA_31,CbiA,ParA HPHIIJEP_00281 224308.BSU16400 8.03e-256 702.0 COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,1ZCJ9@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis regulator FlhF flhF GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02404 - - - - ko00000,ko02035 - - - SRP54 HPHIIJEP_00282 224308.BSU16390 0.0 1248.0 COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,4H9XU@91061|Bacilli,1ZBID@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP HPHIIJEP_00283 224308.BSU16380 3.89e-244 672.0 COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,4HB7Y@91061|Bacilli,1ZBSH@1386|Bacillus 91061|Bacilli N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 HPHIIJEP_00284 224308.BSU16370 1.47e-170 478.0 COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,4HA2E@91061|Bacilli,1ZBJF@1386|Bacillus 91061|Bacilli N Flagellar biosynthetic protein FliR fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 HPHIIJEP_00285 224308.BSU16360 5.23e-50 159.0 COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,4HKVS@91061|Bacilli,1ZI12@1386|Bacillus 91061|Bacilli N Role in flagellar biosynthesis fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 HPHIIJEP_00286 224308.BSU16350 1.21e-141 401.0 COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,4HA79@91061|Bacilli,1ZCWT@1386|Bacillus 91061|Bacilli N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP HPHIIJEP_00287 224308.BSU16340 3.73e-135 385.0 COG3190@1|root,COG3190@2|Bacteria,1VGFI@1239|Firmicutes,4HJJQ@91061|Bacilli,1ZQNA@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis protein, FliO fliZ - - ko:K02418 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliO HPHIIJEP_00288 224308.BSU16330 1.22e-76 229.0 COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,4HGY2@91061|Bacilli,1ZG7Q@1386|Bacillus 91061|Bacilli T response regulator cheY - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg HPHIIJEP_00289 224308.BSU16320 1.38e-253 697.0 COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,4HC56@91061|Bacilli,1ZB7S@1386|Bacillus 91061|Bacilli N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliY GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - CheC,FliMN_C HPHIIJEP_00290 224308.BSU16310 6.61e-231 636.0 COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,4HAAY@91061|Bacilli,1ZCI6@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliM GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C HPHIIJEP_00291 224308.BSU16300 7.95e-78 233.0 COG1580@1|root,COG1580@2|Bacteria,1V6K9@1239|Firmicutes,4HIJZ@91061|Bacilli,1ZI2U@1386|Bacillus 91061|Bacilli N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL HPHIIJEP_00292 224308.BSU16290 1.09e-179 501.0 COG4786@1|root,COG4786@2|Bacteria,1TRA2@1239|Firmicutes,4HBNB@91061|Bacilli,1ZCVW@1386|Bacillus 91061|Bacilli N Flagellar basal body rod flgG GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C HPHIIJEP_00293 224308.BSU16280 2.81e-96 280.0 COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,4HNQK@91061|Bacilli,1ZI5S@1386|Bacillus 91061|Bacilli N Flagellar basal body rod modification protein flgD GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgD HPHIIJEP_00294 224308.BSU16270 3.71e-304 835.0 COG3144@1|root,COG3144@2|Bacteria,1VI6B@1239|Firmicutes,4HGUR@91061|Bacilli,1ZERA@1386|Bacillus 91061|Bacilli N Flagellar hook-length control protein fliK GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02414 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_hook HPHIIJEP_00295 224308.BSU16260 1.51e-78 240.0 COG3334@1|root,COG3334@2|Bacteria,1V87H@1239|Firmicutes,4HM5Z@91061|Bacilli,1ZCXR@1386|Bacillus 91061|Bacilli S MgtE intracellular N domain ylxF - - - - - - - - - - - MgtE_N HPHIIJEP_00296 224308.BSU16250 1.79e-91 268.0 COG2882@1|root,COG2882@2|Bacteria,1V6SQ@1239|Firmicutes,4HJZP@91061|Bacilli,1ZGXV@1386|Bacillus 91061|Bacilli N Flagellar biosynthesis chaperone fliJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02413 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliJ HPHIIJEP_00297 224308.BSU16240 1e-306 837.0 COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,4HAUY@91061|Bacilli,1ZBXU@1386|Bacillus 91061|Bacilli NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase fliI - 3.6.3.14 ko:K02412 ko02040,map02040 - - - ko00000,ko00001,ko01000,ko02035,ko02044 3.A.6.2,3.A.6.3 - - ATP-synt_ab,ATP-synt_ab_N HPHIIJEP_00298 1051501.AYTL01000027_gene1210 4.51e-143 407.0 COG1317@1|root,COG1317@2|Bacteria,1VEUV@1239|Firmicutes,4HG3R@91061|Bacilli,1ZE47@1386|Bacillus 91061|Bacilli NU COG1317 Flagellar biosynthesis type III secretory pathway protein fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH HPHIIJEP_00299 1051501.AYTL01000027_gene1209 6.08e-230 634.0 COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,1ZAQU@1386|Bacillus 91061|Bacilli N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N HPHIIJEP_00300 224308.BSU16210 0.0 933.0 COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,4HBF0@91061|Bacilli,1ZAZN@1386|Bacillus 91061|Bacilli N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C HPHIIJEP_00301 224308.BSU16200 5.5e-53 168.0 COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,4HNZW@91061|Bacilli,1ZIT0@1386|Bacillus 91061|Bacilli N Flagellar hook-basal body fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE HPHIIJEP_00302 224308.BSU16190 8.81e-98 285.0 COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,4HH4W@91061|Bacilli,1ZGA0@1386|Bacillus 91061|Bacilli N Belongs to the flagella basal body rod proteins family flgC GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C HPHIIJEP_00303 224308.BSU16180 4.64e-83 246.0 COG1815@1|root,COG1815@2|Bacteria,1VIK5@1239|Firmicutes,4HX5S@91061|Bacilli,1ZQN0@1386|Bacillus 91061|Bacilli N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod HPHIIJEP_00304 1051501.AYTL01000027_gene1204 1.95e-175 490.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli,1ZBT9@1386|Bacillus 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY HPHIIJEP_00305 224308.BSU16160 0.0 877.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,1ZCWK@1386|Bacillus 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small HPHIIJEP_00306 224308.BSU16150 3.01e-120 344.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,1ZCMN@1386|Bacillus 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome HPHIIJEP_00307 224308.BSU16140 1.13e-217 600.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,1ZB91@1386|Bacillus 91061|Bacilli L tyrosine recombinase XerC xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase HPHIIJEP_00308 224308.BSU16130 6.35e-313 852.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,1ZAR2@1386|Bacillus 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA HPHIIJEP_00309 224308.BSU16120 0.0 1375.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,1ZB7D@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom HPHIIJEP_00310 224308.BSU16110 3.48e-213 588.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,1ZBZ3@1386|Bacillus 91061|Bacilli LU Rossmann fold nucleotide-binding protein involved in DNA uptake dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A HPHIIJEP_00311 224308.BSU16100 3.09e-213 589.0 COG0074@1|root,COG0074@2|Bacteria,1TPIT@1239|Firmicutes,4HA2J@91061|Bacilli,1ZCHE@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16100 CoA_binding,Ligase_CoA HPHIIJEP_00312 224308.BSU16090 6.77e-269 737.0 COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,4HA3W@91061|Bacilli,1ZB9P@1386|Bacillus 91061|Bacilli C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU16090 ATP-grasp_2,Ligase_CoA HPHIIJEP_00313 224308.BSU16080 1.7e-59 183.0 COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HPCF@91061|Bacilli,1ZIW6@1386|Bacillus 91061|Bacilli S homolog of the cytoplasmic domain of flagellar protein FhlB ylqH - - ko:K04061 - - - - ko00000,ko02044 - - - Bac_export_2 HPHIIJEP_00314 224308.BSU16070 0.0 1059.0 2C5DW@1|root,2Z7RX@2|Bacteria,1TT0I@1239|Firmicutes,4HDMQ@91061|Bacilli,1ZCY5@1386|Bacillus 91061|Bacilli - - ylqG - - - - - - - - - - - - HPHIIJEP_00315 224308.BSU16060 5.83e-175 488.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII HPHIIJEP_00316 224308.BSU16050 5.7e-200 554.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,1ZB63@1386|Bacillus 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 HPHIIJEP_00317 224308.BSU16040 8.14e-75 224.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,1ZGDK@1386|Bacillus 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 HPHIIJEP_00318 224308.BSU16030 2.41e-177 493.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1ZD4X@1386|Bacillus 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT HPHIIJEP_00319 224308.BSU16020 1.84e-122 349.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,1ZFP2@1386|Bacillus 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM HPHIIJEP_00320 224308.BSU16010 9.77e-80 237.0 2FI10@1|root,349TX@2|Bacteria,1W0UI@1239|Firmicutes,4HYP9@91061|Bacilli,1ZQSB@1386|Bacillus 91061|Bacilli S YlqD protein ylqD - - - - - - - - - - - YlqD HPHIIJEP_00321 224308.BSU16000 1.2e-49 157.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,1ZIW7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 HPHIIJEP_00322 1051501.AYTL01000027_gene1186 1.13e-58 181.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,1ZGXP@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 HPHIIJEP_00323 224308.BSU15980 3.95e-308 841.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,1ZB4I@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB HPHIIJEP_00324 1051501.AYTL01000027_gene1184 5.64e-66 201.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,1ZH7Z@1386|Bacillus 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 HPHIIJEP_00325 224308.BSU15960 1.96e-113 325.0 28M0G@1|root,2ZJQW@2|Bacteria,1V1BK@1239|Firmicutes,4HHTK@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00326 224308.BSU15950 3.38e-227 627.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,1ZB46@1386|Bacillus 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N HPHIIJEP_00327 224308.BSU15940 0.0 1919.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,1ZAWM@1386|Bacillus 91061|Bacilli D Required for chromosome condensation and partitioning smc GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge HPHIIJEP_00328 224308.BSU15930 2.12e-174 486.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm HPHIIJEP_00329 1051501.AYTL01000027_gene1178 1.15e-43 142.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,1ZHY7@1386|Bacillus 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding HPHIIJEP_00330 224308.BSU15910 3.5e-167 468.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 HPHIIJEP_00331 224308.BSU15900 3.09e-217 600.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,1ZBGQ@1386|Bacillus 91061|Bacilli I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 HPHIIJEP_00332 224308.BSU15890 8.33e-230 634.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,1ZBW8@1386|Bacillus 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis HPHIIJEP_00333 224308.BSU15880 6.22e-121 346.0 COG1349@1|root,COG2050@1|root,COG1349@2|Bacteria,COG2050@2|Bacteria,1V3MJ@1239|Firmicutes,4HHFC@91061|Bacilli,1ZAV1@1386|Bacillus 91061|Bacilli K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism fapR - - - - - - - - - - - 4HBT,HTH_DeoR,MaoC_dehydratas HPHIIJEP_00334 224308.BSU15870 0.0 1335.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,1ZC17@1386|Bacillus 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge HPHIIJEP_00335 224308.BSU15860 1.19e-201 560.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,1ZC9A@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha HPHIIJEP_00336 224308.BSU15850 6.88e-152 427.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,1ZCRK@1386|Bacillus 91061|Bacilli E L-serine dehydratase sdaAB GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta HPHIIJEP_00337 224308.BSU15840 0.0 1033.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,1ZBRP@1386|Bacillus 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 HPHIIJEP_00338 224308.BSU15830 3.65e-78 233.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,1ZG6I@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yloU - - - - - - - - - - - Asp23 HPHIIJEP_00339 224308.BSU15820 7.06e-36 121.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,1ZIVY@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 HPHIIJEP_00340 224308.BSU15800 9.5e-156 436.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,1ZD4A@1386|Bacillus 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic HPHIIJEP_00341 224308.BSU15790 9.44e-153 429.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim HPHIIJEP_00342 224308.BSU15780 1.12e-214 592.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,1ZB4W@1386|Bacillus 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N HPHIIJEP_00343 224308.BSU15770 0.0 1243.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase HPHIIJEP_00344 224308.BSU15760 2.05e-179 499.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 HPHIIJEP_00345 224308.BSU15750 3.07e-263 721.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli,1ZBCJ@1386|Bacillus 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM HPHIIJEP_00346 224308.BSU15740 0.0 877.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,1ZCWU@1386|Bacillus 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB HPHIIJEP_00347 224308.BSU15730 1.49e-224 619.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,1ZBSP@1386|Bacillus 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N HPHIIJEP_00348 224308.BSU15720 4.8e-109 314.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HHMA@91061|Bacilli,1ZGES@1386|Bacillus 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase HPHIIJEP_00349 224308.BSU15710 0.0 1533.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII HPHIIJEP_00350 224308.BSU15700 7.28e-286 781.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,1ZD3R@1386|Bacillus 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein HPHIIJEP_00351 1051501.AYTL01000027_gene1156 6.21e-39 129.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,1ZIVD@1386|Bacillus 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 HPHIIJEP_00352 224308.BSU15680 5.73e-143 403.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,1ZBZI@1386|Bacillus 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin HPHIIJEP_00353 1051501.AYTL01000027_gene1154 3.97e-54 169.0 COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,4HKDP@91061|Bacilli,1ZHVQ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0296 family ylzA - - ko:K09777 - - - - ko00000 - - - DUF370 HPHIIJEP_00354 224308.BSU15660 8.41e-202 559.0 COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,4HAK9@91061|Bacilli,1ZCGE@1386|Bacillus 91061|Bacilli S stress-induced protein yloC - - - - - - - - - - - DUF1732,YicC_N HPHIIJEP_00355 224308.BSU15650 0.0 1679.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus 91061|Bacilli P COG0474 Cation transport ATPase yloB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - iYO844.BSU15650 Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase HPHIIJEP_00356 224308.BSU15640 0.0 1112.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,1ZBGD@1386|Bacillus 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA HPHIIJEP_00357 224308.BSU15630 5.37e-107 309.0 COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,4HIRG@91061|Bacilli,1ZHMG@1386|Bacillus 91061|Bacilli H Siroheme synthase sirC - 1.3.1.76,4.99.1.4 ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03947 RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - NAD_binding_7,Sirohm_synth_M HPHIIJEP_00358 224308.BSU15620 1.45e-187 521.0 COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,4H9RT@91061|Bacilli,1ZGH1@1386|Bacillus 91061|Bacilli S Sirohydrochlorin ferrochelatase sirB - 4.99.1.4 ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R02864 RC01012 ko00000,ko00001,ko00002,ko01000 - - - CbiX HPHIIJEP_00359 224308.BSU15610 4.85e-184 511.0 COG0007@1|root,COG0007@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus 91061|Bacilli H Belongs to the precorrin methyltransferase family cobA GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03194 RC00003,RC00871 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15610 TP_methylase HPHIIJEP_00360 224308.BSU15600 1.59e-141 399.0 COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus 91061|Bacilli P Catalyzes the synthesis of activated sulfate cysC GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase HPHIIJEP_00361 224308.BSU15590 2.62e-285 778.0 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus 91061|Bacilli P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 HPHIIJEP_00362 224308.BSU15580 2.1e-229 634.0 COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus 91061|Bacilli P phosphate transporter cysP GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K16331 - - - - ko00000,ko02000 2.A.20.4 - - PHO4 HPHIIJEP_00363 224308.BSU15570 5.95e-182 504.0 COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus 91061|Bacilli EH Belongs to the PAPS reductase family. CysH subfamily cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15570 PAPS_reduct HPHIIJEP_00365 224308.BSU15560 1.49e-147 416.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,1ZASD@1386|Bacillus 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran HPHIIJEP_00366 224308.BSU15550 6.56e-164 459.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,1ZB1I@1386|Bacillus 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase HPHIIJEP_00367 224308.BSU15540 4.26e-221 610.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,1ZBNC@1386|Bacillus 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15540 DHO_dh HPHIIJEP_00368 224308.BSU15530 1.5e-182 508.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli,1ZBJI@1386|Bacillus 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 HPHIIJEP_00369 224308.BSU15520 0.0 2073.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,1ZCEM@1386|Bacillus 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS HPHIIJEP_00370 224308.BSU15510 1.31e-269 737.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,1ZB7G@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15510 CPSase_sm_chain,GATase HPHIIJEP_00371 224308.BSU15500 0.0 863.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,1ZAS7@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 HPHIIJEP_00372 224308.BSU15490 6.24e-215 593.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,1ZBHG@1386|Bacillus 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N HPHIIJEP_00373 224308.BSU15480 3.05e-293 803.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,1ZBWN@1386|Bacillus 91061|Bacilli F Xanthine uracil pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease HPHIIJEP_00374 224308.BSU15470 4.45e-122 348.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,1ZB3P@1386|Bacillus 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran HPHIIJEP_00375 224308.BSU15460 2.04e-224 617.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,1ZC3M@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HPHIIJEP_00376 224308.BSU15450 2.71e-103 299.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 HPHIIJEP_00377 224308.BSU15440 3.74e-82 243.0 COG1734@1|root,COG1734@2|Bacteria,1UA3Y@1239|Firmicutes,4IKDQ@91061|Bacilli,1ZGM6@1386|Bacillus 91061|Bacilli T COG1734 DnaK suppressor protein ylyA - - - - - - - - - - - zf-dskA_traR HPHIIJEP_00378 224308.BSU15430 0.0 1863.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,1ZAQK@1386|Bacillus 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS HPHIIJEP_00379 224308.BSU15420 6.44e-100 291.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,1ZFNB@1386|Bacillus 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA HPHIIJEP_00380 224308.BSU15410 7.1e-177 493.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,1ZC97@1386|Bacillus 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 HPHIIJEP_00381 224308.BSU15400 1.22e-53 168.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli,1ZHUZ@1386|Bacillus 91061|Bacilli S membrane ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT HPHIIJEP_00382 224308.BSU15390 1.28e-86 256.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,1ZGE0@1386|Bacillus 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF HPHIIJEP_00383 224308.BSU15380 1.28e-161 452.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli,1ZARM@1386|Bacillus 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N HPHIIJEP_00384 224308.BSU15370 9.17e-204 563.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4HFUM@91061|Bacilli,1ZBZZ@1386|Bacillus 91061|Bacilli S Belongs to the multicopper oxidase YfiH RL5 family ylmD GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 HPHIIJEP_00385 224308.BSU15360 3.58e-51 161.0 COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,4HNT3@91061|Bacilli,1ZI0Y@1386|Bacillus 91061|Bacilli S sporulation protein ylmC - - - - - - - - - - - PRC HPHIIJEP_00386 224308.BSU15350 0.0 872.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HBWM@91061|Bacilli,1ZQFB@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase argE - - ko:K20895 ko00730,ko01100,map00730,map01100 - R11313 RC00197 ko00000,ko00001,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HPHIIJEP_00387 224308.BSU15340 1.29e-187 521.0 COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli,1ZBUE@1386|Bacillus 91061|Bacilli P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran HPHIIJEP_00388 224308.BSU15330 7.99e-180 501.0 COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,4H9MN@91061|Bacilli,1ZB53@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigG - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 HPHIIJEP_00389 224308.BSU15320 1.48e-160 451.0 COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,4H9PG@91061|Bacilli,1ZBKD@1386|Bacillus 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigE GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 HPHIIJEP_00390 224308.BSU15310 2.05e-218 603.0 29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,4HDX6@91061|Bacilli,1ZAV2@1386|Bacillus 91061|Bacilli M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR spoIIGA GO:0003674,GO:0003824,GO:0004175,GO:0004190,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0043621,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0070001,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - ko:K06383 - - - - ko00000,ko01000,ko01002 - - - Peptidase_U4 HPHIIJEP_00391 224308.BSU15300 0.0 2786.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus 91061|Bacilli O COG1404 Subtilisin-like serine proteases bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8 HPHIIJEP_00392 224308.BSU15290 2.14e-259 712.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin HPHIIJEP_00393 224308.BSU15280 4.88e-299 818.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,1ZBH1@1386|Bacillus 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA HPHIIJEP_00394 224308.BSU15270 5.37e-76 227.0 COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,4HIMZ@91061|Bacilli,1ZGAQ@1386|Bacillus 91061|Bacilli S small basic protein sbp - - - - - - - - - - - DUF1290 HPHIIJEP_00395 224308.BSU15260 1.06e-132 378.0 COG3879@1|root,COG3879@2|Bacteria,1V2J7@1239|Firmicutes,4HG14@91061|Bacilli,1ZDER@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxX GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 HPHIIJEP_00396 224308.BSU15250 1.35e-143 407.0 COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,4HAN4@91061|Bacilli,1ZE4Z@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylxW GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 HPHIIJEP_00397 224308.BSU15240 1.18e-178 498.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,1ZDSW@1386|Bacillus 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 HPHIIJEP_00398 224308.BSU15230 3.74e-211 584.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,1ZC3F@1386|Bacillus 91061|Bacilli M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU15230 FAD_binding_4,MurB_C HPHIIJEP_00399 224308.BSU15220 4.48e-256 702.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 HPHIIJEP_00400 224308.BSU15210 6.64e-237 653.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBY5@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family spoVE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE HPHIIJEP_00401 224308.BSU15200 0.0 879.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,1ZARV@1386|Bacillus 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M HPHIIJEP_00402 224308.BSU15190 9.59e-220 607.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,1ZBIK@1386|Bacillus 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 HPHIIJEP_00403 224308.BSU15180 0.0 966.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus 91061|Bacilli M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HPHIIJEP_00404 224308.BSU15170 0.0 1267.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZBC0@1386|Bacillus 91061|Bacilli M stage V sporulation protein D spoVD - - ko:K08384 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PASTA,PBP_dimer,Transpeptidase HPHIIJEP_00405 224308.BSU15160 0.0 1384.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,1ZASE@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase HPHIIJEP_00406 224308.BSU15150 3.42e-68 207.0 COG4839@1|root,COG4839@2|Bacteria,1VDUV@1239|Firmicutes,4HKM7@91061|Bacilli,1ZIVC@1386|Bacillus 91061|Bacilli D Essential cell division protein ftsL - - - - - - - - - - - DivIC HPHIIJEP_00407 224308.BSU15140 1.66e-218 603.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,1ZCHN@1386|Bacillus 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 HPHIIJEP_00408 224308.BSU15130 9.82e-102 294.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,1ZFN0@1386|Bacillus 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ HPHIIJEP_00409 224308.BSU15120 0.0 1055.0 COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,4HA2Z@91061|Bacilli,1ZBMV@1386|Bacillus 91061|Bacilli S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH bshC - - ko:K22136 - - - - ko00000 - - - BshC HPHIIJEP_00410 224308.BSU15110 2.27e-214 592.0 COG1893@1|root,COG1893@2|Bacteria,1V1NJ@1239|Firmicutes,4HFWT@91061|Bacilli,1ZFJY@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15110 ApbA,ApbA_C HPHIIJEP_00411 224308.BSU15100 1.33e-115 330.0 COG0454@1|root,COG0454@2|Bacteria,1V259@1239|Firmicutes,4HFSD@91061|Bacilli,1ZFN4@1386|Bacillus 91061|Bacilli K n-acetyltransferase ylbP - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 HPHIIJEP_00412 224308.BSU15090 4.72e-107 311.0 2C8MW@1|root,305IT@2|Bacteria,1V5HI@1239|Firmicutes,4HGP6@91061|Bacilli,1ZBX1@1386|Bacillus 91061|Bacilli S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains ylbO - - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 HPHIIJEP_00413 224308.BSU15080 1.71e-37 125.0 COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0003674,GO:0003735,GO:0005198 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p HPHIIJEP_00414 224308.BSU15070 6.94e-117 335.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,1ZGJH@1386|Bacillus 91061|Bacilli S metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 HPHIIJEP_00416 224308.BSU15060 8.29e-292 797.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,1ZC63@1386|Bacillus 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 HPHIIJEP_00417 224308.BSU15050 7.81e-239 657.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,1ZAW6@1386|Bacillus 91061|Bacilli T Belongs to the peptidase S16 family ylbL - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 HPHIIJEP_00418 224308.BSU15040 2.11e-175 490.0 COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,1ZBCG@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily ylbK GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin HPHIIJEP_00419 224308.BSU15030 1.84e-280 768.0 COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,4HB55@91061|Bacilli,1ZCCT@1386|Bacillus 91061|Bacilli S Sporulation integral membrane protein YlbJ ylbJ - - - - - - - - - - - Gate HPHIIJEP_00420 224308.BSU15020 3.8e-111 319.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,1ZFNZ@1386|Bacillus 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like HPHIIJEP_00421 224308.BSU15010 1.37e-122 350.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,1ZFNI@1386|Bacillus 91061|Bacilli L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 HPHIIJEP_00422 224308.BSU15000 4.36e-52 164.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,1ZI4I@1386|Bacillus 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 HPHIIJEP_00423 224308.BSU14990 2.34e-97 283.0 COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli,1ZG76@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family ylbF - - - - - - - - - - - Com_YlbF HPHIIJEP_00424 224308.BSU14980 1.73e-48 154.0 2ED1C@1|root,336YB@2|Bacteria,1VJ46@1239|Firmicutes,4HPWX@91061|Bacilli,1ZJ6S@1386|Bacillus 91061|Bacilli S YlbE-like protein ylbE - - - - - - - - - - - YlbE HPHIIJEP_00425 224308.BSU14970 3.24e-89 261.0 2DV4S@1|root,32UYM@2|Bacteria,1VA7R@1239|Firmicutes,4HMUX@91061|Bacilli,1ZI1G@1386|Bacillus 91061|Bacilli S Putative coat protein ylbD - - - - - - - - - - - YlbD_coat HPHIIJEP_00426 224308.BSU14960 5.13e-255 699.0 COG2340@1|root,COG2340@2|Bacteria,1UYZ4@1239|Firmicutes,4HBTC@91061|Bacilli,1ZCGK@1386|Bacillus 91061|Bacilli S protein with SCP PR1 domains ylbC - - - - - - - - - - - CAP,CAP_assoc_N HPHIIJEP_00427 224308.BSU14950 1.08e-97 284.0 COG2905@1|root,COG2905@2|Bacteria,1VW3X@1239|Firmicutes,4HJ81@91061|Bacilli,1ZH6S@1386|Bacillus 91061|Bacilli T COG0517 FOG CBS domain ylbB - - - - - - - - - - - CBS HPHIIJEP_00428 224308.BSU14940 1.61e-81 241.0 2AHI2@1|root,317VK@2|Bacteria,1V6HY@1239|Firmicutes,4HJHD@91061|Bacilli,1ZHCP@1386|Bacillus 91061|Bacilli S YugN-like family ylbA - - - - - - - - - - - YugN HPHIIJEP_00429 224308.BSU14930 1.21e-213 590.0 COG3336@1|root,COG3336@2|Bacteria,1TQFK@1239|Firmicutes,4H9WN@91061|Bacilli,1ZBC8@1386|Bacillus 91061|Bacilli S cytochrome c oxidase ctaG - - ko:K02862 - - - - ko00000 - - - Caa3_CtaG HPHIIJEP_00430 224308.BSU14920 6.09e-70 211.0 COG3125@1|root,COG3125@2|Bacteria,1V855@1239|Firmicutes,4HJV7@91061|Bacilli,1ZH0W@1386|Bacillus 91061|Bacilli C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4 ctaF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02277 ko00190,ko01100,map00190,map01100 M00155 - - ko00000,ko00001,ko00002,ko01000 3.D.4.4 - iYO844.BSU14920 COX4_pro HPHIIJEP_00431 224308.BSU14910 1.84e-145 410.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HAHK@91061|Bacilli,1ZBVD@1386|Bacillus 91061|Bacilli C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 ctaE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 ko:K02276 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.4,3.D.4.6 - - COX3 HPHIIJEP_00432 224308.BSU14900 0.0 1243.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 HPHIIJEP_00433 224308.BSU14890 2.38e-252 692.0 COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,1ZAP8@1386|Bacillus 91061|Bacilli C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) ctaC GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3 HPHIIJEP_00434 224308.BSU14880 6.93e-208 576.0 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iSB619.SA_RS05465 UbiA HPHIIJEP_00435 224308.BSU14870 2e-212 587.0 COG1612@1|root,COG1612@2|Bacteria,1TR4W@1239|Firmicutes,4HC12@91061|Bacilli,1ZC0K@1386|Bacillus 91061|Bacilli O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA GO:0000003,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0019954,GO:0022607,GO:0030436,GO:0032502,GO:0034622,GO:0043933,GO:0043934,GO:0044085,GO:0065003,GO:0071840 - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - iSB619.SA_RS05460,iYO844.BSU14870 COX15-CtaA HPHIIJEP_00436 224308.BSU14860 0.0 2275.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,1ZC4R@1386|Bacillus 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA HPHIIJEP_00437 224308.BSU14850 1.05e-272 748.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,1ZBDZ@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family ftsW GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE HPHIIJEP_00438 224308.BSU14840 6.94e-59 182.0 COG4838@1|root,COG4838@2|Bacteria,1VAXB@1239|Firmicutes,4HKIX@91061|Bacilli,1ZI2B@1386|Bacillus 91061|Bacilli S Belongs to the UPF0358 family ylaN - - - - - - - - - - - DUF1507 HPHIIJEP_00439 224308.BSU14830 3.49e-219 605.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,1ZBXX@1386|Bacillus 91061|Bacilli E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - iYO844.BSU02430 Glutaminase HPHIIJEP_00440 224308.BSU14820 1.09e-110 318.0 COG2041@1|root,COG2041@2|Bacteria,1V1EZ@1239|Firmicutes,4HIWI@91061|Bacilli,1ZDPV@1386|Bacillus 91061|Bacilli S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide ylaL - - - - - - - - - - - - HPHIIJEP_00441 224308.BSU14810 3.76e-316 861.0 COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,4HA4V@91061|Bacilli,1ZDIF@1386|Bacillus 91061|Bacilli T ATPase related to phosphate starvation-inducible protein PhoH ylaK - - ko:K07175 - - - - ko00000 - - - PIN_4,PhoH HPHIIJEP_00442 224308.BSU14800 9.93e-126 360.0 2A3AP@1|root,30RSQ@2|Bacteria,1VA69@1239|Firmicutes,4HKTQ@91061|Bacilli,1ZFXZ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ylaJ - - - - - - - - - - - Spore_YhcN_YlaJ HPHIIJEP_00443 224308.BSU14790 3.64e-43 140.0 COG4896@1|root,COG4896@2|Bacteria,1VFMW@1239|Firmicutes,4HNPM@91061|Bacilli,1ZIXV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ylaI - - - - - - - - - - - DUF2197 HPHIIJEP_00444 224308.BSU14780 4.4e-63 193.0 2E309@1|root,32TAR@2|Bacteria,1VBNE@1239|Firmicutes,4HM33@91061|Bacilli,1ZI2F@1386|Bacillus 91061|Bacilli S YlaH-like protein ylaH - - - - - - - - - - - YlaH HPHIIJEP_00445 224308.BSU14770 0.0 1189.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,1ZB9R@1386|Bacillus 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 HPHIIJEP_00446 1051501.AYTL01000027_gene1064 1.56e-30 108.0 2DR2B@1|root,339VK@2|Bacteria,1VNV6@1239|Firmicutes 1239|Firmicutes S Family of unknown function (DUF5325) - - - - - - - - - - - - DUF5325 HPHIIJEP_00447 224308.BSU14750 5.7e-56 183.0 2AR0Q@1|root,31G9I@2|Bacteria,1U9T9@1239|Firmicutes,4IK0K@91061|Bacilli,1ZEZ2@1386|Bacillus 91061|Bacilli - - ylaE - - - - - - - - - - - - HPHIIJEP_00449 224308.BSU14730 2.06e-114 328.0 COG1595@1|root,COG1595@2|Bacteria,1V1S3@1239|Firmicutes,4HG2H@91061|Bacilli,1ZGKM@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily ylaC - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_00450 224308.BSU14720 3.39e-55 172.0 29RZZ@1|root,30D4A@2|Bacteria,1UATQ@1239|Firmicutes,4IM6J@91061|Bacilli,1ZJBE@1386|Bacillus 91061|Bacilli - - ylaB - - - - - - - - - - - - HPHIIJEP_00451 224308.BSU14710 0.0 1191.0 2FH24@1|root,348WX@2|Bacteria,1VZQR@1239|Firmicutes,4IJQ4@91061|Bacilli,1ZDGJ@1386|Bacillus 91061|Bacilli - - ylaA - - - - - - - - - - - - HPHIIJEP_00452 224308.BSU14700 0.0 1014.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 mpl GO:0005575,GO:0005576 3.4.24.28,3.4.24.29 ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C HPHIIJEP_00453 224308.BSU14690 1.01e-220 608.0 COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,1ZDGN@1386|Bacillus 91061|Bacilli Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - - - - - - - - - - LCM HPHIIJEP_00454 224308.BSU14680 4.07e-98 285.0 2FENS@1|root,346N3@2|Bacteria,1VZVT@1239|Firmicutes,4HYCA@91061|Bacilli,1ZIPR@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) family ykzC - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 HPHIIJEP_00455 224308.BSU14670 1.51e-191 531.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,1ZAS1@1386|Bacillus 91061|Bacilli G Inositol monophosphatase suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P HPHIIJEP_00456 224308.BSU14660 4.48e-35 120.0 29S19@1|root,30D5Q@2|Bacteria,1UAVY@1239|Firmicutes,4IM8R@91061|Bacilli,1ZJH7@1386|Bacillus 91061|Bacilli - - ykzI - - - - - - - - - - - - HPHIIJEP_00457 224308.BSU14650 2.15e-151 425.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,1ZCEH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 HPHIIJEP_00458 224308.BSU14640 6.37e-55 171.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,1ZHT9@1386|Bacillus 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 HPHIIJEP_00459 224308.BSU14630 0.0 956.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZAR0@1386|Bacillus 91061|Bacilli E Arginine speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.19 ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00133,M00134 R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C HPHIIJEP_00461 224308.BSU14620 4.55e-83 245.0 COG0526@1|root,COG0526@2|Bacteria,1UAWB@1239|Firmicutes,4IM94@91061|Bacilli,1ZJHW@1386|Bacillus 91061|Bacilli CO COG0526, thiol-disulfide isomerase and thioredoxins slp - - - - - - - - - - - HyaE HPHIIJEP_00462 224308.BSU14610 0.0 911.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,1ZCJR@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes pdhD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim HPHIIJEP_00463 224308.BSU14600 1.47e-301 824.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,1ZAQR@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding HPHIIJEP_00464 1051501.AYTL01000027_gene1050 3.52e-227 626.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,1ZBJ1@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05355,iYO844.BSU14590 Transket_pyr,Transketolase_C HPHIIJEP_00465 224308.BSU14580 1.06e-258 710.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,1ZBE0@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh HPHIIJEP_00466 224308.BSU14570 1.06e-138 394.0 COG0497@1|root,COG0497@2|Bacteria,1V4G3@1239|Firmicutes,4HHDM@91061|Bacilli,1ZH4B@1386|Bacillus 91061|Bacilli L Putative cell-wall binding lipoprotein ykyA - - - - - - - - - - - YkyA HPHIIJEP_00467 224308.BSU14569 1.26e-07 49.7 2DRND@1|root,33CCV@2|Bacteria,1VNPA@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (Tiny_TM_bacill) - - - - - - - - - - - - Tiny_TM_bacill HPHIIJEP_00468 224308.BSU14560 3.96e-131 372.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,1ZB0K@1386|Bacillus 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase HPHIIJEP_00469 224308.BSU14550 1.18e-186 519.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,1ZBY4@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ykrA - - - - - - - - - - - Hydrolase_3,S6PP HPHIIJEP_00470 224308.BSU14540 8.98e-42 137.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,1ZIUI@1386|Bacillus 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 HPHIIJEP_00471 224308.BSU14530 0.0 1108.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,1ZBCD@1386|Bacillus 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL HPHIIJEP_00472 224308.BSU14520 0.0 1114.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HBB2@91061|Bacilli,1ZCHI@1386|Bacillus 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - iYO844.BSU14520 Adenine_deam_C,Amidohydro_1 HPHIIJEP_00473 224308.BSU14510 1.68e-148 419.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N HPHIIJEP_00474 224308.BSU14500 1.02e-199 553.0 COG2105@1|root,COG3703@1|root,COG2105@2|Bacteria,COG3703@2|Bacteria,1V4XC@1239|Firmicutes,4HH0F@91061|Bacilli,1ZJQH@1386|Bacillus 91061|Bacilli P Gamma-glutamyl cyclotransferase, AIG2-like ykqA - - - - - - - - - - - AIG2_2,GGACT HPHIIJEP_00475 224308.BSU14490 2.18e-305 833.0 COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,4HD4A@91061|Bacilli,1ZDWU@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07698 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_9 HPHIIJEP_00476 1051501.AYTL01000027_gene1038 2.63e-58 180.0 COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH5A@1386|Bacillus 91061|Bacilli K of stationary sporulation gene expression abrB - - ko:K06284 - - - - ko00000,ko03000 - - - MazE_antitoxin HPHIIJEP_00477 224308.BSU14470 6.17e-234 644.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HC52@91061|Bacilli,1ZCN2@1386|Bacillus 91061|Bacilli D Rod-share determining protein MreBH mreBH - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl HPHIIJEP_00478 720555.BATR1942_04995 1.09e-18 77.0 29SAF@1|root,30DEY@2|Bacteria,1UB7X@1239|Firmicutes,4IMKP@91061|Bacilli,1ZKCX@1386|Bacillus 91061|Bacilli S Uncharacterized protein YkpC - - - - - - - - - - - - ykpC HPHIIJEP_00479 224308.BSU14450 2.07e-303 826.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 HPHIIJEP_00480 224308.BSU14440 6.74e-214 591.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli,1ZAU6@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C HPHIIJEP_00481 224308.BSU14430 0.0 1061.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,1ZBVV@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn HPHIIJEP_00482 224308.BSU14420 6.35e-51 161.0 29RS7@1|root,30CVY@2|Bacteria,1UAG3@1239|Firmicutes,4IKUG@91061|Bacilli,1ZHMP@1386|Bacillus 91061|Bacilli - - ykoA - - - - - - - - - - - - HPHIIJEP_00483 224308.BSU14410 1.72e-134 381.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZGNJ@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family sipT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 HPHIIJEP_00484 224308.BSU14400 0.0 1142.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZAVB@1386|Bacillus 91061|Bacilli GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) fruA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB HPHIIJEP_00485 224308.BSU14390 9.99e-216 595.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,1ZB76@1386|Bacillus 91061|Bacilli G Belongs to the carbohydrate kinase PfkB family pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB HPHIIJEP_00486 224308.BSU14380 7.41e-176 490.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,1ZBIR@1386|Bacillus 91061|Bacilli K Transcriptional regulator fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR HPHIIJEP_00487 224308.BSU14370 1.92e-265 729.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus 91061|Bacilli V COG0577 ABC-type antimicrobial peptide transport system, permease component yknZ GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HPHIIJEP_00488 224308.BSU14360 6.1e-160 448.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yknY - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_00489 224308.BSU14350 3.32e-233 646.0 COG0845@1|root,COG0845@2|Bacteria,1V5DX@1239|Firmicutes,4HMQM@91061|Bacilli,1ZD1D@1386|Bacillus 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family yknX GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K02005,ko:K13888 - M00709 - - ko00000,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 HPHIIJEP_00490 224308.BSU14340 1.2e-146 415.0 2EJ6V@1|root,33CY2@2|Bacteria,1VPDN@1239|Firmicutes,4HS8D@91061|Bacilli,1ZIQW@1386|Bacillus 91061|Bacilli S Yip1 domain yknW - - - - - - - - - - - Yip1 HPHIIJEP_00491 224308.BSU14330 0.0 1131.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknV GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_00492 224308.BSU14320 0.0 1122.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZASV@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yknU GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_00493 224308.BSU14310 2.82e-44 144.0 COG1977@1|root,COG1977@2|Bacteria,1VERN@1239|Firmicutes,4HNP5@91061|Bacilli,1ZIV7@1386|Bacillus 91061|Bacilli H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS HPHIIJEP_00494 224308.BSU14300 3.83e-109 314.0 COG0314@1|root,COG0314@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,1ZG9N@1386|Bacillus 91061|Bacilli H COG0314 Molybdopterin converting factor, large subunit moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE HPHIIJEP_00495 224308.BSU14290 5.71e-121 345.0 COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,4HNMQ@91061|Bacilli,1ZH3K@1386|Bacillus 91061|Bacilli H molybdopterin-guanine dinucleotide biosynthesis protein mobB - - ko:K03753 - - - - ko00000 - - - MobB HPHIIJEP_00496 224308.BSU14280 4.11e-311 847.0 COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,4HAFT@91061|Bacilli,1ZB4V@1386|Bacillus 91061|Bacilli H molybdopterin moeA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N HPHIIJEP_00497 224308.BSU14270 1.47e-242 666.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF HPHIIJEP_00498 224308.BSU14260 7.57e-141 397.0 COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,4HPX3@91061|Bacilli,1ZIA7@1386|Bacillus 91061|Bacilli H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 HPHIIJEP_00499 224308.BSU14250 1.64e-198 553.0 29RCT@1|root,30CEZ@2|Bacteria,1U9S5@1239|Firmicutes,4IJYN@91061|Bacilli,1ZEMZ@1386|Bacillus 91061|Bacilli - - yknT - - ko:K06437 - - - - ko00000 - - - - HPHIIJEP_00500 224308.BSU14240 4.71e-122 349.0 29AGR@1|root,2ZXGY@2|Bacteria,1W2P8@1239|Firmicutes,4HZNQ@91061|Bacilli,1ZEC3@1386|Bacillus 91061|Bacilli K Repressor of ComK rok - - - - - - - - - - - - HPHIIJEP_00501 224308.BSU14230 2.01e-102 296.0 COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,1ZBFR@1386|Bacillus 91061|Bacilli CO thiol-disulfide ykuV - - - - - - - - - - - AhpC-TSA HPHIIJEP_00502 224308.BSU14220 9.78e-130 368.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ykuU - - - - - - - - - - - 1-cysPrx_C,AhpC-TSA HPHIIJEP_00503 224308.BSU14210 4.1e-181 505.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,1ZCW4@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K22044 - - - - ko00000,ko02000 1.A.23.3 - - MS_channel HPHIIJEP_00504 224308.BSU14200 7.23e-51 160.0 2E5FN@1|root,3307C@2|Bacteria,1VH91@1239|Firmicutes,4HP9B@91061|Bacilli,1ZJ6Z@1386|Bacillus 91061|Bacilli S Belongs to the UPF0180 family ykuS - - - - - - - - - - - UPF0180 HPHIIJEP_00505 224308.BSU14190 1.27e-272 745.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,1ZC15@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HPHIIJEP_00506 224308.BSU14180 1.31e-125 362.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1ZBFG@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep HPHIIJEP_00507 224308.BSU14170 1.03e-101 295.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,1ZGS6@1386|Bacillus 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 HPHIIJEP_00508 224308.BSU14160 1.74e-222 612.0 2AQTM@1|root,31G1Q@2|Bacteria,1U9SX@1239|Firmicutes,4IK02@91061|Bacilli,1ZEXC@1386|Bacillus 91061|Bacilli - - ykuO - - - - - - - - - - - - HPHIIJEP_00509 224308.BSU14150 1.44e-109 315.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HYY9@91061|Bacilli,1ZQAR@1386|Bacillus 91061|Bacilli C Flavodoxin domain - - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 HPHIIJEP_00510 224308.BSU14140 6.52e-216 595.0 COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus 91061|Bacilli K Transcriptional regulator ccpC - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_00511 224308.BSU14130 5.15e-100 290.0 COG0517@1|root,COG0517@2|Bacteria,1V9HN@1239|Firmicutes,4HH3X@91061|Bacilli,1ZGY8@1386|Bacillus 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS HPHIIJEP_00512 1051501.AYTL01000027_gene1002 7.83e-38 126.0 2DFUR@1|root,2ZT80@2|Bacteria,1VPE1@1239|Firmicutes,4HZWS@91061|Bacilli,1ZIPB@1386|Bacillus 91061|Bacilli S Antirepressor AbbA ykzF - - - - - - - - - - - AbbA_antirepres HPHIIJEP_00513 224308.BSU14110 3.06e-120 343.0 COG1978@1|root,COG1978@2|Bacteria,1V6RQ@1239|Firmicutes,4HHG1@91061|Bacilli,1ZR7G@1386|Bacillus 91061|Bacilli S Ribonuclease H-like - - - ko:K09776 - - - - ko00000 - - - RNaseH_like HPHIIJEP_00514 224308.BSU14100 5.16e-50 158.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,1ZI15@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 HPHIIJEP_00515 224308.BSU14090 3.55e-298 813.0 COG2200@1|root,COG2200@2|Bacteria,1UADD@1239|Firmicutes,4HCNX@91061|Bacilli,1ZBWD@1386|Bacillus 91061|Bacilli T Diguanylate phosphodiesterase ykuI - - - - - - - - - - - EAL,YkuI_C HPHIIJEP_00516 224308.BSU14060 2.6e-182 507.0 COG1028@1|root,COG1028@2|Bacteria,1TPDB@1239|Firmicutes,4HAKR@91061|Bacilli,1ZDEP@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fadH - 1.3.1.34 ko:K00219 - - - - ko00000,ko01000 - - - adh_short_C2 HPHIIJEP_00517 224308.BSU14050 2.01e-211 583.0 COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,1ZB99@1386|Bacillus 91061|Bacilli S Metallophosphoesterase ykuE - - ko:K07098 - - - - ko00000 - - - Metallophos HPHIIJEP_00518 224308.BSU14040 5.84e-115 329.0 COG1376@1|root,COG1376@2|Bacteria,1V9XU@1239|Firmicutes,4HKDD@91061|Bacilli,1ZGIN@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykuD - - - - - - - - - - - LysM,YkuD HPHIIJEP_00519 224308.BSU14030 2.55e-305 833.0 COG0477@1|root,COG2814@2|Bacteria,1U72T@1239|Firmicutes,4HCHH@91061|Bacilli,1ZCHP@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ykuC - - - - - - - - - - - MFS_1 HPHIIJEP_00520 224308.BSU14020 3.71e-110 316.0 2ABH1@1|root,310Y3@2|Bacteria,1V4IK@1239|Firmicutes,4HI56@91061|Bacilli,1ZGD1@1386|Bacillus 91061|Bacilli S YkyB-like protein ykyB - - - - - - - - - - - YkyB HPHIIJEP_00521 224308.BSU14010 4.95e-216 596.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,4HCPT@91061|Bacilli,1ZAYA@1386|Bacillus 91061|Bacilli T Chemotaxis protein CheV cheV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - CheW,Response_reg HPHIIJEP_00522 720555.BATR1942_04770 4.27e-22 86.3 29SAK@1|root,30DF4@2|Bacteria,1UB88@1239|Firmicutes,4IMKY@91061|Bacilli,1ZKDP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00523 224308.BSU14000 3.59e-284 776.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase patA - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_00524 224308.BSU13990 0.0 1183.0 COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus 91061|Bacilli T Histidine kinase kinA GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009653,GO:0009987,GO:0030154,GO:0030435,GO:0032502,GO:0042802,GO:0043934,GO:0043937,GO:0043938,GO:0048518,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0051094,GO:0065007 2.7.13.3 ko:K02491 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,MEDS,PAS,PAS_9 HPHIIJEP_00525 224308.BSU13980 0.0 1373.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZEGD@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase HPHIIJEP_00526 224308.BSU13970 1.79e-170 477.0 COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HJ21@91061|Bacilli,1ZDSK@1386|Bacillus 91061|Bacilli J protein with SCP PR1 domains ykwD - - - - - - - - - - - CAP,LysM HPHIIJEP_00527 935836.JAEL01000042_gene4934 1.68e-17 88.6 COG4257@1|root,COG4257@2|Bacteria,1VR6A@1239|Firmicutes,4HT8X@91061|Bacilli,1ZBTB@1386|Bacillus 91061|Bacilli H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid vgb - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - HPHIIJEP_00528 224308.BSU13960 2.33e-202 560.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,1ZBSG@1386|Bacillus 91061|Bacilli I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 HPHIIJEP_00529 224308.BSU13950 0.0 1004.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpC GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0044464,GO:0050896,GO:0050918,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 HPHIIJEP_00530 224308.BSU13940 5.31e-61 192.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,1ZCHR@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ykwB - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_00531 224308.BSU13940 6.15e-57 182.0 COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli,1ZCHR@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ykwB - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_00532 224308.BSU13930 2.49e-256 701.0 COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,4HACB@91061|Bacilli,1ZBPU@1386|Bacillus 91061|Bacilli L Spore photoproduct lyase splB GO:0003674,GO:0003824,GO:0003913,GO:0005488,GO:0005575,GO:0005623,GO:0016829,GO:0016830,GO:0042601,GO:0042763,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070283,GO:0140097 4.1.99.14 ko:K03716 - - - - ko00000,ko01000 - - - - HPHIIJEP_00533 224308.BSU13920 1.54e-51 162.0 2EURH@1|root,33N73@2|Bacteria,1VNQV@1239|Firmicutes,4HRM4@91061|Bacilli,1ZIV4@1386|Bacillus 91061|Bacilli S Transcriptional regulator splA - - ko:K06315 - - - - ko00000,ko03000 - - - SplA HPHIIJEP_00534 224308.BSU13910 0.0 1091.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,1ZAU2@1386|Bacillus 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C HPHIIJEP_00535 224308.BSU13900 1.51e-53 168.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,1ZHX7@1386|Bacillus 91061|Bacilli G phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr HPHIIJEP_00536 224308.BSU13890 0.0 1339.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus 91061|Bacilli G phosphotransferase system ptsG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.199 ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00282,M00809 R02631,R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.6,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_00537 224308.BSU13880 6.87e-168 473.0 COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,4HBB3@91061|Bacilli,1ZBDU@1386|Bacillus 91061|Bacilli K antiterminator glcT - - ko:K03480,ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD HPHIIJEP_00538 224308.BSU13870 5.43e-229 630.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,1ZC0J@1386|Bacillus 91061|Bacilli K Transcriptional regulator ykvZ - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 HPHIIJEP_00540 224308.BSU13860 2.34e-265 726.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,1ZBZE@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase ykvY - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 HPHIIJEP_00541 1051501.AYTL01000027_gene972 3.99e-09 54.7 2BH4M@1|root,32B5K@2|Bacteria,1UB74@1239|Firmicutes,4IMJU@91061|Bacilli,1ZKBC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00542 224308.BSU13850 0.0 1182.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase zosA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase HPHIIJEP_00543 224308.BSU13840 5.79e-117 334.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZEK2@1386|Bacillus 91061|Bacilli CO thiol-disulfide stoA - - - - - - - - - - - AhpC-TSA HPHIIJEP_00544 224308.BSU13830 6.46e-302 825.0 COG2244@1|root,COG2244@2|Bacteria,1VRYZ@1239|Firmicutes,4HV8Z@91061|Bacilli,1ZCGG@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ykvU - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C HPHIIJEP_00545 224308.BSU13820 5.26e-141 399.0 COG3773@1|root,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4IPK9@91061|Bacilli,1ZRER@1386|Bacillus 91061|Bacilli M Cell Wall Hydrolase ykvT - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,LysM HPHIIJEP_00546 224308.BSU13819 2.5e-39 130.0 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes,4HR2E@91061|Bacilli,1ZIUC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00547 224308.BSU13810 5.43e-35 119.0 COG4873@1|root,COG4873@2|Bacteria,1VF7M@1239|Firmicutes,4HPMH@91061|Bacilli,1ZIXH@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ykvS - - - - - - - - - - - DUF2187 HPHIIJEP_00548 224308.BSU13800 2.67e-62 191.0 2E4N6@1|root,32ZH2@2|Bacteria,1VGMB@1239|Firmicutes,4HPMV@91061|Bacilli,1ZJ10@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3219) ykvR - - - - - - - - - - - DUF3219 HPHIIJEP_00549 720555.BATR1942_06725 4.3e-205 569.0 COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HE0C@91061|Bacilli,1ZPVK@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 18 - - - - - - - - - - - - Glyco_hydro_18,SLH HPHIIJEP_00550 224308.BSU13789 7.56e-48 152.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Glyco_hydro_25,LysM,Polysacc_deac_1 HPHIIJEP_00551 224308.BSU13780 1.74e-271 743.0 COG1388@1|root,COG4641@1|root,COG1388@2|Bacteria,COG4641@2|Bacteria,1TRY6@1239|Firmicutes,4HJAS@91061|Bacilli,1ZARJ@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_2,LysM HPHIIJEP_00552 224308.BSU13770 7.68e-172 480.0 COG1028@1|root,COG1028@2|Bacteria,1UZSG@1239|Firmicutes,4HF5D@91061|Bacilli,1ZCT4@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase ykvO - - - - - - - - - - - adh_short_C2 HPHIIJEP_00553 224308.BSU13760 2.8e-81 240.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HVQB@91061|Bacilli,1ZG7Y@1386|Bacillus 91061|Bacilli K Transcriptional regulator ykvN - - - - - - - - - - - HxlR HPHIIJEP_00554 1051501.AYTL01000027_gene960 2.36e-125 355.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli,1ZB8C@1386|Bacillus 91061|Bacilli S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF HPHIIJEP_00555 224308.BSU13740 3.56e-179 498.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli,1ZBRU@1386|Bacillus 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM HPHIIJEP_00556 224308.BSU13730 6.96e-105 302.0 COG0720@1|root,COG0720@2|Bacteria,1V6X6@1239|Firmicutes,4HJ9P@91061|Bacilli,1ZDDT@1386|Bacillus 91061|Bacilli H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS HPHIIJEP_00557 224308.BSU13720 2.61e-160 448.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli,1ZCJD@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC HPHIIJEP_00558 224308.BSU13710 4.08e-228 630.0 COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli,1ZAX1@1386|Bacillus 91061|Bacilli S membrane ykvI - - - - - - - - - - - Spore_permease HPHIIJEP_00559 224308.BSU13700 0.0 1330.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,1ZBTK@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR HPHIIJEP_00560 224308.BSU13690 3.23e-178 498.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motA GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB HPHIIJEP_00561 224308.BSU13680 2.51e-167 469.0 COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus 91061|Bacilli N Flagellar motor protein motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA HPHIIJEP_00562 224308.BSU13670 5.17e-99 287.0 COG1846@1|root,COG1846@2|Bacteria,1V6EE@1239|Firmicutes,4HJ8T@91061|Bacilli,1ZGC6@1386|Bacillus 91061|Bacilli K transcriptional ykvE GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K15973 - - - - ko00000,ko03000 - - - MarR HPHIIJEP_00563 224308.BSU13660 0.0 949.0 COG3852@1|root,COG3852@2|Bacteria,1TPU8@1239|Firmicutes,4HF96@91061|Bacilli,1ZD24@1386|Bacillus 91061|Bacilli T COG0642 Signal transduction histidine kinase kinD - 2.7.13.3 ko:K13532 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,dCache_1 HPHIIJEP_00564 224308.BSU13650 5.84e-95 277.0 2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,4HNC3@91061|Bacilli,1ZI1S@1386|Bacillus 91061|Bacilli - - eag - - - - - - - - - - - - HPHIIJEP_00566 224308.BSU13630 8.82e-68 205.0 COG3339@1|root,COG3339@2|Bacteria,1VPY4@1239|Firmicutes,4IRH9@91061|Bacilli,1ZRUF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 HPHIIJEP_00567 224308.BSU13620 8.7e-123 350.0 COG1791@1|root,COG1791@2|Bacteria,1TT4W@1239|Firmicutes,4HFN3@91061|Bacilli,1ZFZ5@1386|Bacillus 91061|Bacilli S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway mtnD GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010309,GO:0016053,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.13.11.53,1.13.11.54 ko:K08967 ko00270,ko01100,map00270,map01100 M00034 R07363,R07364 RC01866,RC02018,RC02118 ko00000,ko00001,ko00002,ko01000 - - - ARD HPHIIJEP_00568 224308.BSU13610 1.84e-146 412.0 COG0235@1|root,COG0235@2|Bacteria,1V516@1239|Firmicutes,4IQSM@91061|Bacilli,1ZRN8@1386|Bacillus 91061|Bacilli E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) mtnB - 4.2.1.109 ko:K08964 ko00270,ko01100,map00270,map01100 M00034 R07392 RC01939 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II HPHIIJEP_00569 224308.BSU13600 1.19e-173 483.0 COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,4H9ZE@91061|Bacilli,1ZBXD@1386|Bacillus 91061|Bacilli E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) mtnX - 3.1.3.87 ko:K08966 ko00270,ko01100,map00270,map01100 M00034 R07394 RC02074 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13600 HAD HPHIIJEP_00570 224308.BSU13590 9.72e-295 804.0 COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,4HBIK@91061|Bacilli,1ZC2J@1386|Bacillus 91061|Bacilli G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) mtnW GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009853,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016984,GO:0043094,GO:0044237 5.3.2.5 ko:K08965 ko00270,ko01100,map00270,map01100 M00034 R07393 RC02421 ko00000,ko00001,ko00002,ko01000 - - - RuBisCO_large,RuBisCO_large_N HPHIIJEP_00571 224308.BSU13580 9.71e-296 806.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZBB2@1386|Bacillus 91061|Bacilli E Aminotransferase mtnE GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 M00034,M00787 R07396,R11068 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_00572 224308.BSU13570 3.31e-192 532.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,1ZB5Z@1386|Bacillus 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase HPHIIJEP_00573 224308.BSU13560 2.03e-292 797.0 COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,4H9QU@91061|Bacilli,1ZBZS@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate mtnK GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.100 ko:K00899 ko00270,ko01100,map00270,map01100 M00034 R04143 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APH HPHIIJEP_00574 224308.BSU13550 3.8e-252 692.0 COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,4H9WM@91061|Bacilli,1ZCD9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B HPHIIJEP_00576 224308.BSU13540 4.58e-114 327.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,1ZGW4@1386|Bacillus 91061|Bacilli L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K13531 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N HPHIIJEP_00577 224308.BSU13530 0.0 1432.0 COG5002@1|root,COG5002@2|Bacteria,1VUBP@1239|Firmicutes,4HUPW@91061|Bacilli,1ZS15@1386|Bacillus 91061|Bacilli T Histidine kinase kinE - 2.7.13.3 ko:K13533 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 HPHIIJEP_00578 224308.BSU13520 3.34e-244 671.0 COG3594@1|root,COG3594@2|Bacteria,1TPGY@1239|Firmicutes,4HCER@91061|Bacilli,1ZDAV@1386|Bacillus 91061|Bacilli G COG3594 Fucose 4-O-acetylase and related acetyltransferases ykrP - - - - - - - - - - - Acyl_transf_3 HPHIIJEP_00579 224308.BSU13510 7.22e-28 101.0 29S13@1|root,30D5G@2|Bacteria,1UAVK@1239|Firmicutes,4IM8F@91061|Bacilli,1ZJGH@1386|Bacillus 91061|Bacilli - - ykzE - - - - - - - - - - - - HPHIIJEP_00581 224308.BSU13500 2.58e-310 847.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZD2H@1386|Bacillus 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrD - - - - - - - - - - - TrkH HPHIIJEP_00582 224308.BSU13490 2.29e-198 551.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,1ZBW6@1386|Bacillus 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 HPHIIJEP_00583 224308.BSU13480 8.97e-159 446.0 28PJY@1|root,2ZC9F@2|Bacteria,1V390@1239|Firmicutes,4HG7F@91061|Bacilli,1ZDN7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1836) ykrK - - - - - - - - - - - DUF1836 HPHIIJEP_00584 224308.BSU13470 1.4e-36 123.0 2BX75@1|root,32YR8@2|Bacteria,1VJMT@1239|Firmicutes,4HP70@91061|Bacilli,1ZIU2@1386|Bacillus 91061|Bacilli S small acid-soluble spore protein sspD - - ko:K06421 - - - - ko00000 - - - SASP HPHIIJEP_00585 224308.BSU13460 9.93e-200 561.0 2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,4HNII@91061|Bacilli,1ZFAW@1386|Bacillus 91061|Bacilli S Anti-sigma factor N-terminus rsgI - - - - - - - - - - - RsgI_N HPHIIJEP_00586 224308.BSU13450 1.8e-167 469.0 COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,4HEBS@91061|Bacilli,1ZCY4@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r2 HPHIIJEP_00587 224308.BSU13440 4.63e-227 626.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,1ZBPQ@1386|Bacillus 91061|Bacilli P COG0861 Membrane protein TerC, possibly involved in tellurium resistance ykoY - - - - - - - - - - - TerC HPHIIJEP_00588 224308.BSU13430 1.71e-143 405.0 COG0586@1|root,COG0586@2|Bacteria,1V1D4@1239|Firmicutes,4HFSU@91061|Bacilli,1ZCPB@1386|Bacillus 91061|Bacilli S membrane-associated protein ykoX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc HPHIIJEP_00589 224308.BSU13420 0.0 1534.0 COG3300@1|root,COG5001@1|root,COG3300@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,1ZAVY@1386|Bacillus 91061|Bacilli T Diguanylate cyclase ykoW - 2.7.7.65 ko:K21023 ko02025,map02025 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,MHYT HPHIIJEP_00590 224308.BSU13410 5.1e-204 566.0 COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli,1ZB9J@1386|Bacillus 91061|Bacilli L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD ku GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - ko:K10979 ko03450,map03450 - - - ko00000,ko00001,ko03400 - - - Ku HPHIIJEP_00591 224308.BSU13400 0.0 1240.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,4HAJG@91061|Bacilli,1ZB2G@1386|Bacillus 91061|Bacilli L ATP-dependent DNA ligase ligD - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_M HPHIIJEP_00592 224308.BSU13390 9.49e-238 654.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis ykoT - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_00593 224308.BSU13380 0.0 1133.0 28H8D@1|root,2Z7KA@2|Bacteria,1UB21@1239|Firmicutes,4HA47@91061|Bacilli,1ZB3G@1386|Bacillus 91061|Bacilli - - ykoS - - - - - - - - - - - - HPHIIJEP_00594 224308.BSU13370 8.43e-196 542.0 COG1408@1|root,COG1408@2|Bacteria,1TUM2@1239|Firmicutes,4HAX1@91061|Bacilli,1ZDBZ@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ykoQ - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 HPHIIJEP_00595 224308.BSU13360 2.38e-127 362.0 COG0726@1|root,COG0726@2|Bacteria,1V6E9@1239|Firmicutes,4HIR9@91061|Bacilli,1ZHR8@1386|Bacillus 91061|Bacilli G polysaccharide deacetylase ykoP - - - - - - - - - - - - HPHIIJEP_00596 224308.BSU13350 5.42e-278 759.0 COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4HDYW@91061|Bacilli,1ZC45@1386|Bacillus 91061|Bacilli M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase ugtP - 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 - R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,MGDG_synth HPHIIJEP_00597 224308.BSU13340 9.83e-106 305.0 COG1846@1|root,COG1846@2|Bacteria,1V7Z7@1239|Firmicutes,4HJ25@91061|Bacilli,1ZCI8@1386|Bacillus 91061|Bacilli K transcriptional ykoM GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K15973 - - - - ko00000,ko03000 - - - MarR HPHIIJEP_00598 224308.BSU13330 3.04e-36 122.0 29SC8@1|root,30DGU@2|Bacteria,1UB9W@1239|Firmicutes,4IMNN@91061|Bacilli,1ZKHJ@1386|Bacillus 91061|Bacilli - - ykoL - - - - - - - - - - - Fur_reg_FbpA HPHIIJEP_00599 224308.BSU13320 1.63e-25 94.7 29S82@1|root,30DCJ@2|Bacteria,1UB54@1239|Firmicutes,4IMHP@91061|Bacilli,1ZK6F@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00600 224308.BSU13310 1.49e-70 213.0 COG0789@1|root,COG0789@2|Bacteria,1VABB@1239|Firmicutes,4HMSS@91061|Bacilli,1ZHYS@1386|Bacillus 91061|Bacilli K transcriptional tnrA GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0043562,GO:0044212,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071944,GO:0080090,GO:0090293,GO:0090294,GO:0097159,GO:1901363,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - MerR_1 HPHIIJEP_00601 224308.BSU13300 9.86e-300 820.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4HASP@91061|Bacilli,1ZCSG@1386|Bacillus 91061|Bacilli P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - iYO844.BSU13300 CBS,MgtE,MgtE_N HPHIIJEP_00603 1178537.BA1_12699 1.45e-08 51.6 29TAK@1|root,30EHN@2|Bacteria,1UCJT@1239|Firmicutes,4IP1Y@91061|Bacilli,1ZP9H@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00604 224308.BSU13280 1.3e-111 321.0 COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes,4HPJK@91061|Bacilli,1ZJ8Z@1386|Bacillus 91061|Bacilli S Peptidase propeptide and YPEB domain ykoJ - - - - - - - - - - - PepSY HPHIIJEP_00605 224308.BSU13270 3.74e-143 405.0 COG3212@1|root,COG3212@2|Bacteria,1VHVW@1239|Firmicutes,4HP4W@91061|Bacilli,1ZDTW@1386|Bacillus 91061|Bacilli S Peptidase propeptide and YPEB domain ykoI - - - - - - - - - - - PepSY HPHIIJEP_00606 224308.BSU13260 2.46e-306 837.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,1ZB8J@1386|Bacillus 91061|Bacilli T Histidine kinase ykoH - - - - - - - - - - - HAMP,HATPase_c,HisKA HPHIIJEP_00607 224308.BSU13250 2.49e-158 444.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,1ZD1X@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ykoG - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_00608 224308.BSU13240 4.05e-141 398.0 28NV2@1|root,2ZBT9@2|Bacteria,1TQQC@1239|Firmicutes,4HCCT@91061|Bacilli,1ZFNS@1386|Bacillus 91061|Bacilli S YKOF-related Family ykoF - - - - - - - - - - - Ykof HPHIIJEP_00609 224308.BSU13230 1.39e-127 364.0 COG4721@1|root,COG4721@2|Bacteria,1V39N@1239|Firmicutes,4HF32@91061|Bacilli,1ZEPF@1386|Bacillus 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt HPHIIJEP_00610 224308.BSU13220 0.0 1052.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,1ZD95@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 HPHIIJEP_00611 224308.BSU13210 1.27e-173 485.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HCPC@91061|Bacilli,1ZEHA@1386|Bacillus 91061|Bacilli P Cobalt transport protein ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ HPHIIJEP_00612 224308.BSU13200 3.99e-193 536.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS HPHIIJEP_00613 224308.BSU13190 1.05e-225 622.0 COG1404@1|root,COG1404@2|Bacteria,1TPZ5@1239|Firmicutes,4HA5F@91061|Bacilli,1ZPUP@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family isp - - ko:K13275 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 HPHIIJEP_00614 224308.BSU13180 0.0 1511.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,1ZBI7@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 HPHIIJEP_00615 1051501.AYTL01000027_gene901 1.17e-128 367.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,1ZHNV@1386|Bacillus 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 HPHIIJEP_00616 224308.BSU13170 8.05e-106 305.0 COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HJIH@91061|Bacilli,1ZEIN@1386|Bacillus 91061|Bacilli FJ COG0590 Cytosine adenosine deaminases guaD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.3 ko:K01487 ko00230,ko01100,map00230,map01100 - R01676 RC00204 ko00000,ko00001,ko01000 - - - MafB19-deam,dCMP_cyt_deam_1 HPHIIJEP_00617 1274524.BSONL12_08232 2.21e-115 331.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZGGH@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins yoaA - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HPHIIJEP_00618 358681.BBR47_13730 1.72e-90 287.0 COG0477@1|root,COG2814@2|Bacteria,1VUTJ@1239|Firmicutes,4HWU2@91061|Bacilli 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 HPHIIJEP_00619 720554.Clocl_2658 0.0 924.0 COG3321@1|root,COG3321@2|Bacteria,1VU8Z@1239|Firmicutes,24YJI@186801|Clostridia 186801|Clostridia Q Beta-ketoacyl synthase - - - - - - - - - - - - Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,ketoacyl-synt HPHIIJEP_00620 720554.Clocl_2664 6.79e-113 344.0 COG0331@1|root,COG0331@2|Bacteria,1TRDU@1239|Firmicutes,24DDF@186801|Clostridia,3WIDQ@541000|Ruminococcaceae 186801|Clostridia I PFAM Acyl transferase - - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 HPHIIJEP_00621 573061.Clocel_2487 0.0 1294.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae 186801|Clostridia Q TIGRFAM amino acid adenylation domain - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase HPHIIJEP_00622 755731.Clo1100_1304 2.46e-313 913.0 COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,36EG3@31979|Clostridiaceae 186801|Clostridia Q TIGRFAM amino acid adenylation domain - - - - - - - - - - - - Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt HPHIIJEP_00623 649747.HMPREF0083_00279 0.0 1883.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,26Q93@186822|Paenibacillaceae 91061|Bacilli Q Non-ribosomal peptide synthetase modules and related proteins - - - ko:K16123,ko:K16124 ko01054,map01054 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase HPHIIJEP_00624 1405.DJ92_4911 7.13e-62 201.0 COG3208@1|root,COG3208@2|Bacteria,1V3KR@1239|Firmicutes,4HHC8@91061|Bacilli,1ZGM9@1386|Bacillus 91061|Bacilli Q Thioesterase domain nrsA - - - - - - - - - - - Thioesterase HPHIIJEP_00625 1137269.AZWL01000004_gene1921 8.31e-151 441.0 COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria 201174|Actinobacteria Q cytochrome P450 - - - - - - - - - - - - p450 HPHIIJEP_00626 1051501.AYTL01000027_gene899 2.79e-28 111.0 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HDMN@91061|Bacilli,1ZPWM@1386|Bacillus 91061|Bacilli M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_1,TPR_16,TPR_2,TPR_8 HPHIIJEP_00627 224308.BSU13160 8.15e-94 273.0 COG1764@1|root,COG1764@2|Bacteria,1V54N@1239|Firmicutes,4HJCS@91061|Bacilli,1ZHD3@1386|Bacillus 91061|Bacilli O Organic hydroperoxide resistance protein ohrB - - - - - - - - - - - OsmC HPHIIJEP_00628 224308.BSU13150 1.42e-97 284.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,1ZHB6@1386|Bacillus 91061|Bacilli K COG1846 Transcriptional regulators ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_00629 224308.BSU13140 9.76e-93 271.0 COG1764@1|root,COG1764@2|Bacteria,1V54N@1239|Firmicutes,4HJCS@91061|Bacilli,1ZHD3@1386|Bacillus 91061|Bacilli O Organic hydroperoxide resistance protein ohrA - - - - - - - - - - - OsmC HPHIIJEP_00631 224308.BSU13130 1.26e-286 784.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,1ZC00@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh HPHIIJEP_00632 224308.BSU13120 4.3e-255 700.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,1ZAPU@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA HPHIIJEP_00633 224308.BSU13110 5.81e-218 601.0 COG0788@1|root,COG0788@2|Bacteria,1TSN4@1239|Firmicutes,4HAW2@91061|Bacilli,1ZAYE@1386|Bacillus 91061|Bacilli F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) purU - 3.5.1.10 ko:K01433 ko00630,ko00670,map00630,map00670 - R00944 RC00026,RC00111 ko00000,ko00001,ko01000 - - - ACT,Formyl_trans_N HPHIIJEP_00634 224308.BSU13100 1.36e-66 202.0 COG2076@1|root,COG2076@2|Bacteria,1VAQQ@1239|Firmicutes,4HKMP@91061|Bacilli,1ZHZ0@1386|Bacillus 91061|Bacilli P Multidrug resistance protein ykkD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K18925 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1.5 - - Multi_Drug_Res HPHIIJEP_00635 224308.BSU13090 1.27e-72 218.0 COG2076@1|root,COG2076@2|Bacteria,1VA2G@1239|Firmicutes,4HKGV@91061|Bacilli,1ZHW4@1386|Bacillus 91061|Bacilli P Multidrug resistance protein ykkC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K18924 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1.5 - - Multi_Drug_Res HPHIIJEP_00636 224308.BSU13080 5.73e-125 355.0 COG1670@1|root,COG1670@2|Bacteria,1V4IY@1239|Firmicutes,4HG60@91061|Bacilli,1ZFNH@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins ykkB - - - - - - - - - - - Acetyltransf_3 HPHIIJEP_00637 224308.BSU13070 1.07e-126 360.0 COG2318@1|root,COG2318@2|Bacteria,1VXC8@1239|Firmicutes,4HWVP@91061|Bacilli,1ZH7I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF664) ykkA - - - - - - - - - - - DUF664,DinB_2 HPHIIJEP_00638 224308.BSU13060 3.95e-167 468.0 COG2323@1|root,COG2323@2|Bacteria,1V95K@1239|Firmicutes,4HIRN@91061|Bacilli,1ZQ05@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) ykjA - - - - - - - - - - - DUF421 HPHIIJEP_00639 720555.BATR1942_03695 2.11e-16 73.6 290T0@1|root,2ZNF3@2|Bacteria,1W534@1239|Firmicutes,4I1ZV@91061|Bacilli,1ZPGP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00640 224308.BSU13040 1.26e-287 785.0 COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,1TRG2@1239|Firmicutes,4HAU3@91061|Bacilli,1ZAP9@1386|Bacillus 91061|Bacilli C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress hmp GO:0000041,GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009987,GO:0015669,GO:0015671,GO:0015893,GO:0016491,GO:0016645,GO:0016646,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0030001,GO:0033554,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042493,GO:0042737,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044270,GO:0044464,GO:0046209,GO:0046210,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051213,GO:0051234,GO:0051409,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0071500,GO:0071949,GO:0072593,GO:0097159,GO:1901265,GO:1901363,GO:2001057 1.14.12.17,1.18.1.3 ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 M00538 R02550,R03562,R05666,R09513 RC00269,RC00490,RC02556 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_6,Globin,NAD_binding_1 HPHIIJEP_00641 224308.BSU13030 1.55e-119 342.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,1ZGQ9@1386|Bacillus 91061|Bacilli I Acyl-CoA hydrolase ykhA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - - - - - - - - - - 4HBT HPHIIJEP_00642 224308.BSU13020 1.78e-205 568.0 COG1834@1|root,COG1834@2|Bacteria,1VDT8@1239|Firmicutes,4ISAW@91061|Bacilli,1ZCTN@1386|Bacillus 91061|Bacilli E Amidinotransferase ykgA - - - - - - - - - - - Amidinotransf HPHIIJEP_00643 224308.BSU13010 1.29e-257 705.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,1ZANH@1386|Bacillus 91061|Bacilli G 6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase HPHIIJEP_00644 224308.BSU13000 8.44e-237 651.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily ykfD - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00645 224308.BSU12990 1.78e-210 582.0 COG0791@1|root,COG0791@2|Bacteria,1TSZ0@1239|Firmicutes,4HBUM@91061|Bacilli,1ZD7T@1386|Bacillus 91061|Bacilli M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) ykfC - 3.4.14.13 ko:K20742 - - - - ko00000,ko01000,ko01002 - - - NLPC_P60 HPHIIJEP_00646 224308.BSU12980 5.42e-254 697.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,1ZC5Y@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N HPHIIJEP_00647 224308.BSU12970 5.33e-222 612.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HAWT@91061|Bacilli,1ZC09@1386|Bacillus 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF ykfA - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 HPHIIJEP_00649 224308.BSU12960 0.0 1103.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein dppE GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K16199 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - SBP_bac_5 HPHIIJEP_00650 224308.BSU12950 1.29e-234 646.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily dppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00651 224308.BSU12940 3.02e-224 619.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppC - - ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - - BPD_transp_1,OppC_N HPHIIJEP_00652 224308.BSU12930 9.7e-204 565.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components dppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K16200 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - iYO844.BSU12930 BPD_transp_1 HPHIIJEP_00653 224308.BSU12920 3.29e-195 541.0 COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,4HC5R@91061|Bacilli,1ZC41@1386|Bacillus 91061|Bacilli E D-aminopeptidase dppA - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - iYO844.BSU12920 Peptidase_M55 HPHIIJEP_00654 224308.BSU12910 5.77e-179 500.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZCP4@1386|Bacillus 91061|Bacilli E Pyrroline-5-carboxylate reductase proG - 1.5.1.2 ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015,M00429 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000,ko02044 - - - F420_oxidored,P5CR_dimer HPHIIJEP_00655 224308.BSU12900 3.99e-283 778.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HPHIIJEP_00657 224308.BSU12890 2.21e-229 632.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis ykcC - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 HPHIIJEP_00658 224308.BSU12880 0.0 1164.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,1ZCFV@1386|Bacillus 91061|Bacilli M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family ykcB - - - - - - - - - - - PMT_2 HPHIIJEP_00659 224308.BSU12870 2.82e-233 641.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,1ZBUA@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ykcA - - ko:K15975 - - - - ko00000 - - - Glyoxalase HPHIIJEP_00660 224308.BSU12860 1.74e-307 839.0 COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,4HBGT@91061|Bacilli,1ZCVT@1386|Bacillus 91061|Bacilli E amino acid steT GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 HPHIIJEP_00661 224308.BSU12850 1.85e-144 407.0 COG1392@1|root,COG1392@2|Bacteria,1V3AP@1239|Firmicutes,4IRDI@91061|Bacilli,1ZRTM@1386|Bacillus 91061|Bacilli P COG1392 Phosphate transport regulator (distant homolog of PhoU) ykaA - - ko:K07220 - - - - ko00000 - - - PhoU_div HPHIIJEP_00662 224308.BSU12840 1.54e-225 623.0 COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,4HAPD@91061|Bacilli,1ZBFE@1386|Bacillus 91061|Bacilli P phosphate transporter pit GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 HPHIIJEP_00663 224308.BSU12830 3.4e-175 488.0 2CDMR@1|root,33VU0@2|Bacteria,1U2MF@1239|Firmicutes,4HW8B@91061|Bacilli,1ZE5J@1386|Bacillus 91061|Bacilli S Toxin SpoIISA, type II toxin-antitoxin system spoIISA - - ko:K06388 - - - - ko00000 - - - SpoIISA_toxin HPHIIJEP_00664 224308.BSU12820 1.78e-31 110.0 29S32@1|root,30D7K@2|Bacteria,1UAYF@1239|Firmicutes,4IMBF@91061|Bacilli,1ZJQE@1386|Bacillus 91061|Bacilli S Stage II sporulation protein SB spoIISB - - ko:K06389 - - - - ko00000 - - - SpoIISB_antitox HPHIIJEP_00666 224308.BSU12810 3.73e-208 576.0 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,1ZB8D@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase xlyA - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,LysM,PG_binding_1,SLH HPHIIJEP_00667 224308.BSU12800 8.12e-53 166.0 2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,4HP5W@91061|Bacilli,1ZKKG@1386|Bacillus 91061|Bacilli S SPP1 phage holin xhlB - - - - - - - - - - - Holin_SPP1 HPHIIJEP_00668 224308.BSU12790 7.71e-52 164.0 2EUET@1|root,33MX4@2|Bacteria,1VKRJ@1239|Firmicutes,4HS03@91061|Bacilli,1ZIPZ@1386|Bacillus 91061|Bacilli S Haemolysin XhlA xhlA - - - - - - - - - - - XhlA HPHIIJEP_00669 224308.BSU12780 6.89e-195 541.0 29TBY@1|root,30EJ0@2|Bacteria,1UCMF@1239|Firmicutes,4IP3K@91061|Bacilli,1ZPBV@1386|Bacillus 91061|Bacilli - - xepA - - - - - - - - - - - - HPHIIJEP_00670 224308.BSU12770 6.35e-31 108.0 29RZE@1|root,30D3R@2|Bacteria,1UAT1@1239|Firmicutes,4IM5V@91061|Bacilli,1ZJ9F@1386|Bacillus 91061|Bacilli - - xkdX - - - - - - - - - - - Phage_XkdX HPHIIJEP_00671 720555.BATR1942_04055 8.66e-58 180.0 2BREE@1|root,32KD7@2|Bacteria,1U22K@1239|Firmicutes,4IBJV@91061|Bacilli,1ZH0P@1386|Bacillus 91061|Bacilli S XkdW protein - - - - - - - - - - - - XkdW HPHIIJEP_00672 1051501.AYTL01000027_gene856 0.0 1156.0 292XD@1|root,2ZQEV@2|Bacteria,1V48I@1239|Firmicutes,4HS4X@91061|Bacilli,1ZFE2@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00673 224308.BSU12749 7.36e-55 171.0 2EKUT@1|root,33EIE@2|Bacteria,1VMJP@1239|Firmicutes,4HR3P@91061|Bacilli,1ZP25@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00674 224308.BSU12740 2.55e-131 373.0 COG3778@1|root,COG3778@2|Bacteria,1VKFB@1239|Firmicutes,4HSXC@91061|Bacilli,1ZGZU@1386|Bacillus 91061|Bacilli S Uncharacterised protein conserved in bacteria (DUF2313) - - - - - - - - - - - - DUF2313 HPHIIJEP_00675 224308.BSU12730 2.08e-242 667.0 COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,4HCTP@91061|Bacilli,1ZB2D@1386|Bacillus 91061|Bacilli S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Baseplate_J HPHIIJEP_00676 224308.BSU12720 3.67e-88 259.0 COG3628@1|root,COG3628@2|Bacteria,1VJ3Z@1239|Firmicutes,4HPXD@91061|Bacilli,1ZG3F@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2634) xkdS - - - - - - - - - - - DUF2634 HPHIIJEP_00677 1051501.AYTL01000027_gene851 3.56e-52 164.0 29RS3@1|root,30CVT@2|Bacteria,1UAFU@1239|Firmicutes,4IKU7@91061|Bacilli,1ZHKX@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2577) xkdR - - - - - - - - - - - DUF2577 HPHIIJEP_00678 224308.BSU12700 2.31e-232 639.0 COG4193@1|root,COG4193@2|Bacteria,1VAT1@1239|Firmicutes,4HQVE@91061|Bacilli,1ZBZG@1386|Bacillus 91061|Bacilli G NLP P60 protein xkdQ - - - - - - - - - - - - HPHIIJEP_00679 224308.BSU12690 6.91e-156 437.0 COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,4HFRJ@91061|Bacilli,1ZD2J@1386|Bacillus 91061|Bacilli S Lysin motif xkdP - - - - - - - - - - - LysM HPHIIJEP_00680 224308.BSU12680 0.0 1284.0 COG3953@1|root,COG5412@1|root,COG3953@2|Bacteria,COG5412@2|Bacteria,1VAT4@1239|Firmicutes,4HMYI@91061|Bacilli,1ZFFP@1386|Bacillus 91061|Bacilli L Transglycosylase SLT domain xkdO - - - - - - - - - - - SLT HPHIIJEP_00681 224308.BSU12671 3.34e-101 293.0 2DQYD@1|root,339DA@2|Bacteria,1VIHA@1239|Firmicutes,4HS2Z@91061|Bacilli,1ZDQV@1386|Bacillus 91061|Bacilli S Phage XkdN-like tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_5 HPHIIJEP_00682 224308.BSU12660 6.01e-99 287.0 2CBAP@1|root,32S1D@2|Bacteria,1VEC7@1239|Firmicutes,4IRT1@91061|Bacilli,1ZEZD@1386|Bacillus 91061|Bacilli S Phage tail tube protein xkdM - - - - - - - - - - - DUF2001 HPHIIJEP_00683 224308.BSU12650 0.0 892.0 28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,4HFJP@91061|Bacilli,1ZJRF@1386|Bacillus 91061|Bacilli S Phage tail sheath C-terminal domain xkdK - - - - - - - - - - - Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N HPHIIJEP_00684 224308.BSU12640 2.87e-101 293.0 28Y6W@1|root,2ZK27@2|Bacteria,1W3G3@1239|Firmicutes,4I0HC@91061|Bacilli,1ZFEX@1386|Bacillus 91061|Bacilli - - xkdJ - - - - - - - - - - - - HPHIIJEP_00685 224308.BSU12630 1.38e-113 325.0 2EFQM@1|root,30H1B@2|Bacteria,1TYGV@1239|Firmicutes,4HZQ3@91061|Bacilli,1ZFEH@1386|Bacillus 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component xkdI - - - - - - - - - - - HK97-gp10_like HPHIIJEP_00686 224308.BSU12620 1.75e-84 248.0 2EHGE@1|root,33B8A@2|Bacteria,1VKQF@1239|Firmicutes,4HZ7D@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF3599) yqbH - - - - - - - - - - - DUF3599 HPHIIJEP_00687 224308.BSU12619 1.63e-82 244.0 2ESBD@1|root,33JW4@2|Bacteria,1VP51@1239|Firmicutes,4HYYW@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3199) yqbG - - - - - - - - - - - DUF3199 HPHIIJEP_00688 224308.BSU12610 3.91e-217 600.0 COG4653@1|root,COG4653@2|Bacteria,1V0XG@1239|Firmicutes,4HN8Z@91061|Bacilli,1ZCB6@1386|Bacillus 91061|Bacilli S Phage capsid family xkdG - - - - - - - - - - - Phage_capsid HPHIIJEP_00689 224308.BSU12600 1.99e-176 494.0 COG0338@1|root,COG0338@2|Bacteria,1V1FT@1239|Firmicutes,4HGCH@91061|Bacilli,1ZEM9@1386|Bacillus 91061|Bacilli L Putative phage serine protease XkdF xkdF3 - - - - - - - - - - - Peptidase_S78_2 HPHIIJEP_00690 224308.BSU12590 0.0 979.0 COG5518@1|root,COG5518@2|Bacteria,1TT5R@1239|Firmicutes,4HEHM@91061|Bacilli,1ZE9D@1386|Bacillus 91061|Bacilli S portal protein yqbA - - - - - - - - - - - Phage_portal HPHIIJEP_00691 224308.BSU12580 0.0 873.0 COG1783@1|root,COG1783@2|Bacteria,1TRQP@1239|Firmicutes,4HDMY@91061|Bacilli,1ZCXF@1386|Bacillus 91061|Bacilli S phage terminase, large subunit xtmB - - ko:K06909 - - - - ko00000 - - - Terminase_3,Terminase_3C HPHIIJEP_00692 224308.BSU12570 4.58e-177 494.0 COG3728@1|root,COG5484@1|root,COG3728@2|Bacteria,COG5484@2|Bacteria,1V8HJ@1239|Firmicutes,4HJ4Z@91061|Bacilli,1ZEK7@1386|Bacillus 91061|Bacilli L phage terminase small subunit xtmA - - ko:K07474 - - - - ko00000 - - - Ftsk_gamma,Phage_terminase,Terminase_2 HPHIIJEP_00693 224308.BSU12560 2.72e-108 313.0 COG1595@1|root,COG1595@2|Bacteria,1VAEY@1239|Firmicutes,4HMVP@91061|Bacilli,1ZJ9T@1386|Bacillus 91061|Bacilli K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog xpf - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r4_2 HPHIIJEP_00697 224308.BSU12530 3.55e-151 427.0 COG1484@1|root,COG1484@2|Bacteria,1V48P@1239|Firmicutes,4HJWT@91061|Bacilli,1ZG1R@1386|Bacillus 91061|Bacilli L Bacterial dnaA protein xkdC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - - - - - - - - - - IstB_IS21 HPHIIJEP_00698 224308.BSU12520 1.07e-202 560.0 COG1522@1|root,COG1522@2|Bacteria,1VVNW@1239|Firmicutes,4HWH8@91061|Bacilli,1ZFTW@1386|Bacillus 91061|Bacilli K sequence-specific DNA binding xkdB - - - - - - - - - - - - HPHIIJEP_00700 224308.BSU12510 2.01e-74 223.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,1ZISZ@1386|Bacillus 91061|Bacilli K Helix-turn-helix XRE-family like proteins xre - - - - - - - - - - - HTH_19,HTH_3 HPHIIJEP_00701 224308.BSU12500 1.79e-143 404.0 COG2856@1|root,COG2856@2|Bacteria,1VF4T@1239|Firmicutes,4HP2V@91061|Bacilli,1ZIKA@1386|Bacillus 91061|Bacilli E IrrE N-terminal-like domain xkdA - - - - - - - - - - - Peptidase_M78 HPHIIJEP_00702 224308.BSU12490 4.54e-204 564.0 COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4H9XR@91061|Bacilli,1ZBZ9@1386|Bacillus 91061|Bacilli P Catalase yjqC GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - ko:K07217 - - - - ko00000 - - - Mn_catalase HPHIIJEP_00703 224308.BSU12480 5.3e-137 388.0 COG4195@1|root,COG4195@2|Bacteria,1VBQ5@1239|Firmicutes,4HK5Q@91061|Bacilli,1ZQV8@1386|Bacillus 91061|Bacilli S Pfam:DUF867 yjqB - - - - - - - - - - - Gamma_PGA_hydro HPHIIJEP_00704 224308.BSU12470 3.19e-79 236.0 arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,4HJ0W@91061|Bacilli,1ZH97@1386|Bacillus 91061|Bacilli S Bacterial PH domain yjqA - - - - - - - - - - - bPH_1 HPHIIJEP_00705 224308.BSU12460 2.96e-215 595.0 COG1388@1|root,COG3409@1|root,COG5632@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,COG5632@2|Bacteria,1V5B9@1239|Firmicutes,4HJY4@91061|Bacilli,1ZIM6@1386|Bacillus 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase xlyB - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,LysM,PG_binding_1 HPHIIJEP_00706 224308.BSU12450 1.79e-55 172.0 COG2350@1|root,COG2350@2|Bacteria,1VYYQ@1239|Firmicutes,4HY97@91061|Bacilli 91061|Bacilli S YCII-related domain - - - - - - - - - - - - YCII HPHIIJEP_00708 1051501.AYTL01000027_gene816 8.59e-272 743.0 COG0457@1|root,COG0457@2|Bacteria,1UUXQ@1239|Firmicutes,4I402@91061|Bacilli,1ZDKN@1386|Bacillus 91061|Bacilli S Response regulator aspartate phosphatase rapA - - ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - TPR_12,TPR_16 HPHIIJEP_00709 224308.BSU12420 1.37e-310 845.0 COG0465@1|root,COG0465@2|Bacteria,1TPA8@1239|Firmicutes,4HDJY@91061|Bacilli,1ZBWY@1386|Bacillus 91061|Bacilli O AAA domain (dynein-related subfamily) VCP - - - - - - - - - - - AAA HPHIIJEP_00710 224308.BSU12410 1.91e-103 299.0 COG2318@1|root,COG2318@2|Bacteria,1V359@1239|Firmicutes,4HGA1@91061|Bacilli,1ZH6K@1386|Bacillus 91061|Bacilli S DinB family yjoA - - - - - - - - - - - DinB HPHIIJEP_00711 224308.BSU12400 4.56e-167 468.0 COG0730@1|root,COG0730@2|Bacteria,1TQFD@1239|Firmicutes,4HBT4@91061|Bacilli,1ZDN3@1386|Bacillus 91061|Bacilli S membrane transporter protein yjnA - - ko:K07090 - - - - ko00000 - - - TauE HPHIIJEP_00712 224308.BSU12390 0.0 981.0 COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,4HAQZ@91061|Bacilli,1ZB6X@1386|Bacillus 91061|Bacilli G Altronate uxaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0008867,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019577,GO:0019579,GO:0019580,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046392,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.42,4.2.1.7 ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00631 R01540,R05608 RC00543 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU02510 GD_AH_C,SAF HPHIIJEP_00713 224308.BSU12380 0.0 968.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4HCQC@91061|Bacilli,1ZCF4@1386|Bacillus 91061|Bacilli G tagaturonate reductase activity uxaB GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.58 ko:K00041 ko00040,ko01100,map00040,map01100 M00631 R02555 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C HPHIIJEP_00714 224308.BSU12370 9.87e-238 654.0 COG1609@1|root,COG1609@2|Bacteria,1UCPU@1239|Firmicutes,4HDJ7@91061|Bacilli,1ZQ1F@1386|Bacillus 91061|Bacilli K transcriptional exuR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_00715 224308.BSU12360 9.24e-288 788.0 COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,4HEVA@91061|Bacilli,1ZC6J@1386|Bacillus 91061|Bacilli G Sugar (and other) transporter exuT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03535,ko:K08191 - - - - ko00000,ko02000 2.A.1.14.1,2.A.1.14.2 - iYO844.BSU02480 MFS_1 HPHIIJEP_00716 224308.BSU12350 2.23e-195 542.0 COG1028@1|root,COG1028@2|Bacteria,1TQ3V@1239|Firmicutes,4HBSW@91061|Bacilli,1ZBI3@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yjmF - - - - - - - - - - - adh_short,adh_short_C2 HPHIIJEP_00717 224308.BSU12340 2.18e-270 738.0 COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,4H9UR@91061|Bacilli,1ZD3F@1386|Bacillus 91061|Bacilli G Catalyzes the dehydration of D-mannonate uxuA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0071704,GO:0072329,GO:1901575 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - - UxuA HPHIIJEP_00718 224308.BSU12330 1.71e-241 664.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HBDT@91061|Bacilli,1ZCJC@1386|Bacillus 91061|Bacilli E Alcohol dehydrogenase GroES-like domain yjmD - 1.1.1.380 ko:K08322 ko00040,ko01100,map00040,map01100 - R10848 RC00085 ko00000,ko00001,ko01000 - - iYO844.BSU12330 ADH_N,ADH_zinc_N HPHIIJEP_00719 224308.BSU12320 3.45e-240 660.0 COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,4HB6X@91061|Bacilli,1ZB9H@1386|Bacillus 91061|Bacilli C Belongs to the LDH2 MDH2 oxidoreductase family allD - 1.1.1.350 ko:K00073 ko00230,ko01120,map00230,map01120 - R02935,R02936 RC00169 ko00000,ko00001,ko01000 - - - Ldh_2 HPHIIJEP_00720 224308.BSU12310 4.15e-312 852.0 COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,4HUTW@91061|Bacilli,1ZR5M@1386|Bacillus 91061|Bacilli G symporter YjmB - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 HPHIIJEP_00721 224308.BSU12300 0.0 952.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,4HCGI@91061|Bacilli,1ZBR3@1386|Bacillus 91061|Bacilli G glucuronate isomerase uxaC - 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - - UxaC HPHIIJEP_00722 224308.BSU12290 3.56e-279 763.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yjlD - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU12290 Pyr_redox_2 HPHIIJEP_00723 224308.BSU12280 1.39e-87 258.0 COG2427@1|root,32RCT@2|Bacteria,1V7FZ@1239|Firmicutes,4HK07@91061|Bacilli,1ZR46@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1641) yjlC - - - - - - - - - - - DUF1641 HPHIIJEP_00724 224308.BSU12270 1.04e-119 341.0 COG4297@1|root,COG4297@2|Bacteria,1V6MJ@1239|Firmicutes,4HJGB@91061|Bacilli,1ZGYD@1386|Bacillus 91061|Bacilli S Cupin domain yjlB - - - - - - - - - - - Cupin_1,Cupin_2 HPHIIJEP_00725 224308.BSU12260 6.04e-223 615.0 COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli,1ZB35@1386|Bacillus 91061|Bacilli EG Putative multidrug resistance efflux transporter yjlA - - - - - - - - - - - EmrE HPHIIJEP_00726 224308.BSU12250 2.79e-175 489.0 COG1117@1|root,COG1117@2|Bacteria,1V2UH@1239|Firmicutes,4HDCU@91061|Bacilli,1ZPYW@1386|Bacillus 91061|Bacilli P ATPases associated with a variety of cellular activities yjkB - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran HPHIIJEP_00727 224308.BSU12240 9.04e-156 439.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,1ZB6C@1386|Bacillus 91061|Bacilli S transport system, permease component ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 HPHIIJEP_00728 224308.BSU12230 8.69e-189 525.0 COG1587@1|root,COG1587@2|Bacteria,1V0K1@1239|Firmicutes,4HFWP@91061|Bacilli,1ZCRM@1386|Bacillus 91061|Bacilli H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 HPHIIJEP_00729 224308.BSU12229 1.11e-41 136.0 28XHF@1|root,2ZJEU@2|Bacteria,1W6IS@1239|Firmicutes,4HZXN@91061|Bacilli,1ZJZF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00730 224308.BSU12220 8.74e-280 765.0 COG1819@1|root,COG1819@2|Bacteria,1TSPC@1239|Firmicutes,4HB9I@91061|Bacilli,1ZB3Z@1386|Bacillus 91061|Bacilli CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase yjiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008194,GO:0016740,GO:0016757,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - - - - - - - - - - Glyco_tran_28_C,UDPGT HPHIIJEP_00731 224308.BSU12210 6.72e-286 781.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 yjiB GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006629,GO:0006706,GO:0006707,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016042,GO:0016053,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016713,GO:0017144,GO:0018130,GO:0019752,GO:0020037,GO:0032787,GO:0034641,GO:0036199,GO:0042364,GO:0042440,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046148,GO:0046164,GO:0046394,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.46,1.14.15.13 ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 HPHIIJEP_00733 224308.BSU12190 1.19e-143 405.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,1ZD9E@1386|Bacillus 91061|Bacilli F ADP-ribose pyrophosphatase yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N HPHIIJEP_00735 224308.BSU12170 1.6e-122 350.0 COG2427@1|root,COG2427@2|Bacteria,1VDZ4@1239|Firmicutes,4HP7W@91061|Bacilli,1ZDHJ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1641) yjgD - - - - - - - - - - - DUF1641 HPHIIJEP_00736 224308.BSU12160 0.0 2005.0 COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,4IS5E@91061|Bacilli,1ZS18@1386|Bacillus 91061|Bacilli C formate dehydrogenase (NAD+) activity yjgC GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 HPHIIJEP_00737 224308.BSU12150 4.96e-133 377.0 2E0RN@1|root,32W9R@2|Bacteria,1VBGS@1239|Firmicutes,4HKSB@91061|Bacilli,1ZIAP@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4309) yjgB - - - - - - - - - - - DUF4309 HPHIIJEP_00738 224308.BSU12140 1.38e-59 185.0 COG0642@1|root,COG2205@2|Bacteria,1VBSA@1239|Firmicutes,4HKPR@91061|Bacilli,1ZHY1@1386|Bacillus 91061|Bacilli T Protein of unknown function (DUF2809) yjgA - - - - - - - - - - - DUF2809 HPHIIJEP_00739 224308.BSU12130 1.42e-213 590.0 COG5504@1|root,COG5504@2|Bacteria,1TT7P@1239|Firmicutes,4HH4B@91061|Bacilli,1ZD4T@1386|Bacillus 91061|Bacilli O Predicted Zn-dependent protease (DUF2268) yjfC - - - - - - - - - - - DUF2268 HPHIIJEP_00740 224308.BSU12120 1.13e-29 105.0 2DR71@1|root,33AGR@2|Bacteria,1VKHI@1239|Firmicutes,4IMK8@91061|Bacilli,1ZKBW@1386|Bacillus 91061|Bacilli S Putative motility protein yjfB - - - - - - - - - - - YjfB_motility HPHIIJEP_00741 224308.BSU12110 2.22e-108 312.0 2DT08@1|root,33I4U@2|Bacteria,1W0PN@1239|Firmicutes,4HYRZ@91061|Bacilli,1ZMTC@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2690) - - - - - - - - - - - - DUF2690 HPHIIJEP_00742 224308.BSU12100 0.0 903.0 COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,1ZC54@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase yjeA GO:0005575,GO:0016020 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - DUF3298,DUF4163,Polysacc_deac_1 HPHIIJEP_00744 224308.BSU12080 4.36e-223 616.0 COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HBJT@91061|Bacilli,1ZCJT@1386|Bacillus 91061|Bacilli O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - iYO844.BSU12080 UbiA HPHIIJEP_00745 224308.BSU12070 2.31e-69 209.0 2C2RW@1|root,32WKK@2|Bacteria,1VDHU@1239|Firmicutes,4HJU1@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4306) yjdJ - - - - - - - - - - - DUF4306 HPHIIJEP_00746 224308.BSU12069 1.02e-38 129.0 2E715@1|root,331JW@2|Bacteria,1VIN9@1239|Firmicutes,4HQH3@91061|Bacilli,1ZJ0A@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4177) - - - - - - - - - - - - DUF4177 HPHIIJEP_00747 224308.BSU12060 1.18e-104 303.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHFK@91061|Bacilli,1ZGGN@1386|Bacillus 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ebsC - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit HPHIIJEP_00749 224308.BSU12040 1.21e-115 331.0 COG1670@1|root,COG1670@2|Bacteria,1VB6W@1239|Firmicutes,4HP5I@91061|Bacilli,1ZJ1I@1386|Bacillus 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HPHIIJEP_00750 224308.BSU12030 9.24e-76 229.0 28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,4HMY0@91061|Bacilli,1ZIDK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2992) yjdF3 - - - - - - - - - - - DUF2992 HPHIIJEP_00751 224308.BSU12020 8.8e-241 660.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,1ZDJI@1386|Bacillus 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI HPHIIJEP_00752 224308.BSU12010 0.0 1201.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1ZC31@1386|Bacillus 91061|Bacilli G phosphotransferase system manP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - iSB619.SA_RS13955 PTS_EIIA_2,PTS_EIIC,PTS_IIB HPHIIJEP_00753 224308.BSU12000 0.0 1256.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HB6A@91061|Bacilli,1ZQ0H@1386|Bacillus 91061|Bacilli GKT transcriptional antiterminator manR - - ko:K02538,ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB HPHIIJEP_00754 720555.BATR1942_03645 8.81e-61 187.0 2C7E8@1|root,3476F@2|Bacteria,1VYZK@1239|Firmicutes,4HYJE@91061|Bacilli,1ZIN3@1386|Bacillus 91061|Bacilli - - yjcN - - - - - - - - - - - - HPHIIJEP_00755 224308.BSU11970 1.27e-61 189.0 COG1359@1|root,COG1359@2|Bacteria 2|Bacteria S Antibiotic biosynthesis monooxygenase yjcS GO:0003674,GO:0003824 - - - - - - - - - - ABM HPHIIJEP_00758 1196029.ALIM01000034_gene2022 9.36e-41 136.0 2BWJU@1|root,304V5@2|Bacteria,1TX8U@1239|Firmicutes,4IKVN@91061|Bacilli,1ZHWV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00759 1430331.EP10_16270 4.41e-24 94.7 2BWJU@1|root,340PU@2|Bacteria,1VWNB@1239|Firmicutes,4HX8G@91061|Bacilli,1WHM7@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00761 224308.BSU11900 6.07e-273 748.0 COG5505@1|root,COG5505@2|Bacteria,1TSC8@1239|Firmicutes,4HBJU@91061|Bacilli,1ZCH1@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF819) yjcL - - - - - - - - - - - DUF819 HPHIIJEP_00762 224308.BSU11890 7.14e-128 363.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,1ZGG6@1386|Bacillus 91061|Bacilli J Alanine acetyltransferase yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HPHIIJEP_00763 224308.BSU11880 1.84e-280 766.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metC GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11880 Cys_Met_Meta_PP HPHIIJEP_00764 224308.BSU11870 1.98e-273 748.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP HPHIIJEP_00765 224308.BSU11860 1.57e-176 491.0 COG2382@1|root,COG2382@2|Bacteria,1UCAC@1239|Firmicutes,4HC02@91061|Bacilli,1ZBAQ@1386|Bacillus 91061|Bacilli P COG2382 Enterochelin esterase and related enzymes yjcH - - ko:K07214 - - - - ko00000 - - - Esterase HPHIIJEP_00766 224308.BSU11850 1.2e-121 347.0 COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli,1ZG9R@1386|Bacillus 91061|Bacilli J Belongs to the 2H phosphoesterase superfamily. YjcG family yjcG - - - - - - - - - - - 2_5_RNA_ligase2 HPHIIJEP_00767 224308.BSU11840 1.1e-93 273.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,1ZH1Q@1386|Bacillus 91061|Bacilli S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 HPHIIJEP_00768 224308.BSU11839 6.31e-51 161.0 29RK5@1|root,30CPB@2|Bacteria,1UA5W@1239|Firmicutes,4IKGI@91061|Bacilli,1ZGY6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00769 224308.BSU11820 0.0 1506.0 COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,4HBVF@91061|Bacilli,1ZCF6@1386|Bacillus 91061|Bacilli L DNA helicase yjcD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - CoiA,UvrD-helicase,UvrD_C HPHIIJEP_00770 224308.BSU11810 1.88e-52 165.0 2E36V@1|root,32Y6J@2|Bacteria,1VFDU@1239|Firmicutes,4HY6K@91061|Bacilli,1ZHWX@1386|Bacillus 91061|Bacilli S Stage VI sporulation protein F spoVIF - - - - - - - - - - - SpoVIF HPHIIJEP_00773 224308.BSU11790 5.03e-75 224.0 2CDF4@1|root,32RXN@2|Bacteria,1VACE@1239|Firmicutes,4HKM4@91061|Bacilli,1ZHZZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1360) yjcA - - - - - - - - - - - DUF1360 HPHIIJEP_00774 1051501.AYTL01000027_gene727 2.34e-66 204.0 29RIB@1|root,30CMA@2|Bacteria,1UA32@1239|Firmicutes,4IKCH@91061|Bacilli,1ZGFD@1386|Bacillus 91061|Bacilli S Spore Coat Protein X and V domain cotV - - ko:K06340 - - - - ko00000 - - - Coat_X HPHIIJEP_00775 1051501.AYTL01000027_gene726 9.3e-32 114.0 2ARSC@1|root,31H3P@2|Bacteria,1UAGS@1239|Firmicutes,4IKV7@91061|Bacilli,1ZHSG@1386|Bacillus 91061|Bacilli - - cotW - - ko:K06341 - - - - ko00000 - - - - HPHIIJEP_00776 720555.BATR1942_03525 1.23e-95 281.0 2CFVW@1|root,32S2K@2|Bacteria,1VBNQ@1239|Firmicutes,4HMD7@91061|Bacilli,1ZGPY@1386|Bacillus 91061|Bacilli S Spore Coat Protein X and V domain cotX - - ko:K06342 - - - - ko00000 - - - Coat_X HPHIIJEP_00777 224308.BSU11750 3.12e-124 352.0 29X3J@1|root,30ISA@2|Bacteria,1V4YJ@1239|Firmicutes,4HHNC@91061|Bacilli,1ZDHZ@1386|Bacillus 91061|Bacilli S Spore coat protein Z cotY - - ko:K06343 - - - - ko00000 - - - Spore-coat_CotZ HPHIIJEP_00778 224308.BSU11740 4.57e-108 310.0 28Q17@1|root,2ZCJP@2|Bacteria,1V1H6@1239|Firmicutes,4HGUD@91061|Bacilli,1ZESU@1386|Bacillus 91061|Bacilli S Spore coat protein cotZ - - ko:K06344 - - - - ko00000 - - - Spore-coat_CotZ HPHIIJEP_00779 224308.BSU11730 1.71e-102 303.0 2EECC@1|root,3386N@2|Bacteria,1VFWU@1239|Firmicutes,4HQI6@91061|Bacilli,1ZDKY@1386|Bacillus 91061|Bacilli S Spore coat protein yjbX GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0044464,GO:0071944 - - - - - - - - - - Spore_coat_CotO HPHIIJEP_00780 224308.BSU11720 1.23e-182 508.0 COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,4H9YN@91061|Bacilli,1ZAP0@1386|Bacillus 91061|Bacilli I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HPHIIJEP_00781 224308.BSU11710 3.98e-190 528.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,1ZCQT@1386|Bacillus 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin HPHIIJEP_00782 224308.BSU11700 8.78e-238 654.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,1ZBR4@1386|Bacillus 91061|Bacilli H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 thiF GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF HPHIIJEP_00783 224308.BSU11690 6.78e-174 486.0 COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,4HBSI@91061|Bacilli,1ZB9S@1386|Bacillus 91061|Bacilli H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG HPHIIJEP_00784 224308.BSU11680 8.9e-41 134.0 COG2104@1|root,COG2104@2|Bacteria 2|Bacteria H thiamine diphosphate biosynthetic process thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - iJN678.ycf40 ThiS HPHIIJEP_00785 224308.BSU11670 1.81e-274 749.0 COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,4HD2K@91061|Bacilli,1ZCZM@1386|Bacillus 91061|Bacilli E Glycine oxidase thiO GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 - R01374,R07463,R09493 RC00006,RC00025,RC01788 ko00000,ko00001,ko01000 - - - DAO HPHIIJEP_00786 224308.BSU11660 1.34e-137 390.0 COG0352@1|root,COG0352@2|Bacteria,1V6KJ@1239|Firmicutes,4HIM9@91061|Bacilli,1ZH29@1386|Bacillus 91061|Bacilli H Transcriptional regulator TenI tenI GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.3.99.10 ko:K10810 ko00730,ko01100,map00730,map01100 - R09977 RC02766 ko00000,ko00001,ko01000,ko03000 - - - TMP-TENI HPHIIJEP_00787 224308.BSU11650 5.7e-177 492.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,1ZQWS@1386|Bacillus 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 HPHIIJEP_00788 224308.BSU11640 0.0 1118.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,1ZBJR@1386|Bacillus 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N HPHIIJEP_00789 224308.BSU11630 2.71e-179 498.0 COG0639@1|root,COG0639@2|Bacteria,1TPCI@1239|Firmicutes,4HBD8@91061|Bacilli,1ZBK8@1386|Bacillus 91061|Bacilli T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP prpE GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.16,3.6.1.41 ko:K01090,ko:K01525 ko00230,map00230 - R00125 RC00002 ko00000,ko00001,ko01000 - - - Metallophos HPHIIJEP_00790 224308.BSU11620 5.21e-203 562.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,1ZB25@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 HPHIIJEP_00791 224308.BSU11610 2.94e-194 538.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,1ZAQP@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase HPHIIJEP_00792 224308.BSU11600 5.06e-145 409.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,1ZBM8@1386|Bacillus 91061|Bacilli S GTP pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT HPHIIJEP_00793 224308.BSU11590 1.87e-81 241.0 2E3PJ@1|root,32YMN@2|Bacteria,1VGBJ@1239|Firmicutes,4HNU4@91061|Bacilli,1ZIVU@1386|Bacillus 91061|Bacilli S Belongs to the UPF0738 family yjbL - - - - - - - - - - - - HPHIIJEP_00794 224308.BSU11580 2.1e-129 368.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1ZH0U@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yjbK - - - - - - - - - - - CYTH HPHIIJEP_00795 1051501.AYTL01000027_gene706 3.42e-127 367.0 COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1ZH33@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yjbJ - - - - - - - - - - - SLT HPHIIJEP_00796 224308.BSU11560 8.58e-94 273.0 COG2346@1|root,COG2346@2|Bacteria,1V6JN@1239|Firmicutes,4HMCZ@91061|Bacilli,1ZQR2@1386|Bacillus 91061|Bacilli S Bacterial-like globin yjbI - - ko:K06886 - - - - ko00000 - - - Bac_globin HPHIIJEP_00797 224308.BSU11550 1.32e-218 602.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,1ZATS@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis yjbH - - - - - - - - - - - Thioredoxin_5 HPHIIJEP_00799 224308.BSU11549 2.68e-28 102.0 2AP4C@1|root,31E5Z@2|Bacteria,1U9RE@1239|Firmicutes,4HSI2@91061|Bacilli,1ZJ77@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00800 224308.BSU11540 0.0 1304.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,1ZCHA@1386|Bacillus 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N HPHIIJEP_00801 224308.BSU11530 1.71e-279 763.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1ZCFD@1386|Bacillus 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA HPHIIJEP_00802 224308.BSU11520 4.65e-149 420.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HDV3@91061|Bacilli,1ZAV4@1386|Bacillus 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC mecA GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K16511 - - - - ko00000 - - - MecA HPHIIJEP_00803 224308.BSU11510 2.37e-142 403.0 COG0861@1|root,COG0861@2|Bacteria,1UYA9@1239|Firmicutes,4HETB@91061|Bacilli,1ZRX5@1386|Bacillus 91061|Bacilli P Integral membrane protein TerC family yjbE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - TerC HPHIIJEP_00804 224308.BSU11500 1.01e-87 258.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,1ZFK4@1386|Bacillus 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC HPHIIJEP_00805 224308.BSU11490 8.88e-132 374.0 COG0454@1|root,COG0456@2|Bacteria,1TSZY@1239|Firmicutes,4HAYD@91061|Bacilli,1ZD7N@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjbC - - - - - - - - - - - Acetyltransf_7 HPHIIJEP_00806 224308.BSU11480 7.88e-259 712.0 COG0477@1|root,COG2814@2|Bacteria,1V9VP@1239|Firmicutes,4HX3Y@91061|Bacilli,1ZS7H@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily yjbB - - - - - - - - - - - MFS_1 HPHIIJEP_00807 224308.BSU11470 1.27e-219 605.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00808 224308.BSU11460 1.37e-249 686.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00809 224308.BSU11450 7.55e-212 586.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,1ZC9B@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - - BPD_transp_1,OppC_N HPHIIJEP_00810 224308.BSU11440 1.03e-212 588.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,1ZAUS@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 HPHIIJEP_00811 224308.BSU11430 0.0 1091.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein oppA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 HPHIIJEP_00812 224308.BSU11420 6.15e-235 646.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,1ZCUY@1386|Bacillus 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b HPHIIJEP_00813 224308.BSU11410 3.18e-190 526.0 28IPR@1|root,2Z8PJ@2|Bacteria,1TPYR@1239|Firmicutes,4HBI7@91061|Bacilli,1ZAX0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0736 family yjbA - - - - - - - - - - - DUF3603 HPHIIJEP_00814 224308.BSU11400 1.03e-208 578.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,1ZCNS@1386|Bacillus 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components appC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N HPHIIJEP_00815 1051501.AYTL01000027_gene687 9.55e-216 597.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 HPHIIJEP_00816 1051501.AYTL01000027_gene686 0.0 1042.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus 91061|Bacilli E COG0747 ABC-type dipeptide transport system, periplasmic component appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 HPHIIJEP_00817 224308.BSU11370 1.99e-235 647.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,1ZBA4@1386|Bacillus 91061|Bacilli E Belongs to the ABC transporter superfamily appF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00818 224308.BSU11360 1.76e-233 642.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily appD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439,M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25 - - ABC_tran,oligo_HPY HPHIIJEP_00819 224308.BSU11350 5.27e-190 527.0 COG5504@1|root,COG5504@2|Bacteria,1UYP6@1239|Firmicutes,4HFSY@91061|Bacilli,1ZCYK@1386|Bacillus 91061|Bacilli O Zn-dependent protease yjaZ - - - - - - - - - - - DUF2268 HPHIIJEP_00820 224308.BSU11340 5.08e-301 820.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt HPHIIJEP_00821 224308.BSU11330 1.61e-221 611.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,1ZAQ1@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU11330 ACP_syn_III,ACP_syn_III_C HPHIIJEP_00822 224308.BSU11320 4.43e-30 108.0 2BSPY@1|root,32MSR@2|Bacteria,1U2D5@1239|Firmicutes,4IBYU@91061|Bacilli,1ZHZD@1386|Bacillus 91061|Bacilli - - yjzB - - - - - - - - - - - - HPHIIJEP_00823 1051501.AYTL01000027_gene679 1.07e-35 121.0 2C7Y5@1|root,2ZW4E@2|Bacteria,1W5UC@1239|Firmicutes,4HZZW@91061|Bacilli,1ZJ0V@1386|Bacillus 91061|Bacilli S ComZ comZ - - ko:K02254 - - - - ko00000,ko02044 - - - ComZ HPHIIJEP_00824 224308.BSU11300 3.7e-234 643.0 COG1744@1|root,COG1744@2|Bacteria,1UY2H@1239|Firmicutes,4HCI5@91061|Bacilli,1ZBN4@1386|Bacillus 91061|Bacilli S Transcriptional activator protein med med - - ko:K05519,ko:K07335 - - - - ko00000,ko03000 - - - Bmp HPHIIJEP_00825 224308.BSU11290 5.84e-129 366.0 29HWM@1|root,30IFG@2|Bacteria,1UIYB@1239|Firmicutes,4ISWX@91061|Bacilli,1ZKCK@1386|Bacillus 91061|Bacilli - - yjaV - - - - - - - - - - - - HPHIIJEP_00826 224308.BSU11280 2.42e-182 506.0 COG2267@1|root,COG2267@2|Bacteria,1UZM1@1239|Firmicutes,4HFJW@91061|Bacilli,1ZD5F@1386|Bacillus 91061|Bacilli I carboxylic ester hydrolase activity yjaU - - - - - - - - - - - Hydrolase_4 HPHIIJEP_00827 326423.RBAM_011270 2.17e-23 90.1 2DRQH@1|root,33CMT@2|Bacteria,1VMJ6@1239|Firmicutes,4HR1S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2929) yjzD - - - - - - - - - - - DUF2929 HPHIIJEP_00828 224308.BSU11260 2.51e-39 130.0 2EG5I@1|root,339XF@2|Bacteria,1VN1D@1239|Firmicutes,4HRD8@91061|Bacilli,1ZR8P@1386|Bacillus 91061|Bacilli S YjzC-like protein yjzC - - - - - - - - - - - YjzC HPHIIJEP_00829 224308.BSU11250 6.07e-225 620.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,1ZC5E@1386|Bacillus 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N HPHIIJEP_00830 224308.BSU11240 0.0 1991.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HABE@91061|Bacilli,1ZPZA@1386|Bacillus 91061|Bacilli EF Carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS HPHIIJEP_00831 224308.BSU11230 9.47e-262 716.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4HAYC@91061|Bacilli,1ZBBD@1386|Bacillus 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase HPHIIJEP_00832 224308.BSU11220 5.65e-277 757.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli,1ZC2Y@1386|Bacillus 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 HPHIIJEP_00833 224308.BSU11210 1.27e-175 490.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,4HH91@91061|Bacilli,1ZF3H@1386|Bacillus 91061|Bacilli E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase HPHIIJEP_00834 224308.BSU11200 7.1e-293 799.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli,1ZAU3@1386|Bacillus 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ HPHIIJEP_00835 224308.BSU11190 1.43e-252 692.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli,1ZBHP@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC HPHIIJEP_00836 1051501.AYTL01000027_gene666 3.24e-114 328.0 COG2271@1|root,COG2271@2|Bacteria,1TT4P@1239|Firmicutes,4HDSQ@91061|Bacilli,1ZG23@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily yitZ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_00837 224308.BSU11170 0.0 922.0 COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli,1ZD7D@1386|Bacillus 91061|Bacilli C D-arabinono-1,4-lactone oxidase yitY - - - - - - - - - - - ALO,FAD_binding_4 HPHIIJEP_00838 1051501.AYTL01000027_gene664 1.74e-31 110.0 COG0401@1|root,COG0401@2|Bacteria,1VHHJ@1239|Firmicutes,4HPX1@91061|Bacilli,1ZJHE@1386|Bacillus 91061|Bacilli S Proteolipid membrane potential modulator - - - - - - - - - - - - Pmp3 HPHIIJEP_00839 224308.BSU11160 4.63e-68 206.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,1ZH2A@1386|Bacillus 91061|Bacilli S metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P HPHIIJEP_00840 224308.BSU11150 1.02e-184 513.0 COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,4HBCG@91061|Bacilli,1ZBIJ@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yitV - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 HPHIIJEP_00841 224308.BSU11140 8.78e-198 547.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZC4W@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 HPHIIJEP_00842 224308.BSU11139 1.01e-25 95.5 2EVBZ@1|root,33NSG@2|Bacteria,1VMU1@1239|Firmicutes,4I1MA@91061|Bacilli,1ZIEQ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3813) - - - - - - - - - - - - DUF3813 HPHIIJEP_00843 1051501.AYTL01000027_gene658 9.69e-94 275.0 2AYP4@1|root,339GZ@2|Bacteria,1VFTB@1239|Firmicutes 1239|Firmicutes S Intracellular proteinase inhibitor ipi - - - - - - - - - - - BsuPI HPHIIJEP_00844 224308.BSU11120 2.29e-189 527.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,1ZDFA@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yitT - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_00845 224308.BSU11110 3.72e-201 557.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitS - - - - - - - - - - - DegV HPHIIJEP_00846 224308.BSU11100 0.0 1050.0 COG3227@1|root,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli,1ZCEP@1386|Bacillus 91061|Bacilli E Peptidase M4 nprB GO:0005575,GO:0005576 3.4.24.28 ko:K01400,ko:K08777 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - FTP,PepSY,Peptidase_M4,Peptidase_M4_C HPHIIJEP_00847 224308.BSU11090 4.59e-59 182.0 2E6JV@1|root,3316R@2|Bacteria,1VHSE@1239|Firmicutes,4HQJY@91061|Bacilli,1ZIRE@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF3784) yitR - - - - - - - - - - - DUF3784 HPHIIJEP_00848 224308.BSU11080 1.23e-119 343.0 2C85J@1|root,2ZKN3@2|Bacteria,1W5AD@1239|Firmicutes,4I1GW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00849 224308.BSU11079 2.08e-77 230.0 COG1695@1|root,COG1695@2|Bacteria,1VXXB@1239|Firmicutes,4HNVK@91061|Bacilli,1ZHYM@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR HPHIIJEP_00850 224308.BSU11070 3.29e-127 361.0 2CE3Z@1|root,3348B@2|Bacteria,1VF6Z@1239|Firmicutes,4HPIA@91061|Bacilli,1ZPGV@1386|Bacillus 91061|Bacilli S Sporulation delaying protein SdpA - - - - - - - - - - - - SdpA HPHIIJEP_00851 224308.BSU11055 1.42e-218 603.0 28UJT@1|root,2ZGQB@2|Bacteria,1VNVF@1239|Firmicutes,4HRVJ@91061|Bacilli,1ZM9H@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00852 224308.BSU11040 4.16e-122 350.0 29TCH@1|root,30EJM@2|Bacteria,1UCNB@1239|Firmicutes,4IP4F@91061|Bacilli,1ZPD0@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00853 224308.BSU11030 2.75e-204 565.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,1ZASM@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yitL - - ko:K00243 - - - - ko00000 - - - S1_2 HPHIIJEP_00854 224308.BSU11020 6.1e-77 233.0 COG1666@1|root,COG1666@2|Bacteria,1VQZH@1239|Firmicutes,4HUT5@91061|Bacilli,1ZRBD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0234 family yitK - - ko:K09767 - - - - ko00000 - - - DUF520 HPHIIJEP_00855 224308.BSU11010 0.0 1205.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,4HAB5@91061|Bacilli,1ZBGC@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine yitJ - 1.5.1.20,2.1.1.10 ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 M00377 R00650,R01224,R07168 RC00003,RC00035,RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR,S-methyl_trans HPHIIJEP_00856 224308.BSU11000 7.23e-92 270.0 COG2153@1|root,COG2153@2|Bacteria,1UIYA@1239|Firmicutes,4ISWW@91061|Bacilli 91061|Bacilli S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 HPHIIJEP_00857 224308.BSU10990 6.12e-195 541.0 COG0454@1|root,COG0454@2|Bacteria,1UHT6@1239|Firmicutes,4IS8U@91061|Bacilli,1ZS32@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain yitH - - - - - - - - - - - Acetyltransf_10 HPHIIJEP_00858 224308.BSU10980 8.28e-291 795.0 COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yitG - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,Sugar_tr,TRI12 HPHIIJEP_00859 224308.BSU10970 4.32e-283 771.0 COG4948@1|root,COG4948@2|Bacteria,1TZ0E@1239|Firmicutes,4HDTT@91061|Bacilli 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family yitF - 5.5.1.27 ko:K18983 ko00053,map00053 - R10847 RC03287 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N HPHIIJEP_00860 1051501.AYTL01000027_gene640 6.77e-145 410.0 COG1284@1|root,COG1284@2|Bacteria,1V5G7@1239|Firmicutes,4HHDF@91061|Bacilli,1ZBEZ@1386|Bacillus 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitE - - - - - - - - - - - YitT_membrane HPHIIJEP_00861 224308.BSU10950 7.15e-179 498.0 COG1809@1|root,COG1809@2|Bacteria,1V20V@1239|Firmicutes,4HDSM@91061|Bacilli,1ZEWC@1386|Bacillus 91061|Bacilli S synthase yitD - 4.4.1.19 ko:K08097 ko00680,ko01120,map00680,map01120 M00358 R07476 RC01799 ko00000,ko00001,ko00002,ko01000 - - - ComA HPHIIJEP_00862 224308.BSU10940 5.62e-155 436.0 COG2045@1|root,COG2045@2|Bacteria,1TTEV@1239|Firmicutes,4HGDY@91061|Bacilli,1ZFKP@1386|Bacillus 91061|Bacilli H Belongs to the ComB family - GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 ko:K05979 ko00680,ko01120,map00680,map01120 M00358 R05789 RC00428 ko00000,ko00001,ko00002,ko01000 - - - 2-ph_phosp HPHIIJEP_00863 224308.BSU10930 6.18e-181 502.0 COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,4HA9E@91061|Bacilli,1ZCBJ@1386|Bacillus 91061|Bacilli EH Belongs to the PAPS reductase family. CysH subfamily cysH GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15570 PAPS_reduct HPHIIJEP_00864 224308.BSU10920 7.62e-293 798.0 COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,4HC20@91061|Bacilli,1ZCB4@1386|Bacillus 91061|Bacilli P Belongs to the sulfate adenylyltransferase family sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 HPHIIJEP_00865 224308.BSU10910 4.06e-145 408.0 COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,4HB96@91061|Bacilli,1ZBCZ@1386|Bacillus 91061|Bacilli P Catalyzes the synthesis of activated sulfate cysC GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 M00176 R00509,R04928 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase HPHIIJEP_00866 224308.BSU10900 5.29e-198 548.0 COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,4HCKX@91061|Bacilli,1ZEU4@1386|Bacillus 91061|Bacilli I hydrolases or acyltransferases (alpha beta hydrolase superfamily) yisY - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Abhydrolase_4 HPHIIJEP_00867 224308.BSU10890 2.15e-96 286.0 COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,4HHBX@91061|Bacilli,1ZDT3@1386|Bacillus 91061|Bacilli S Pentapeptide repeats (9 copies) yisX - - - - - - - - - - - Pentapeptide,Pentapeptide_4 HPHIIJEP_00868 224308.BSU10880 0.0 950.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydfD - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR HPHIIJEP_00869 224308.BSU10870 6.06e-137 389.0 COG1279@1|root,COG1279@2|Bacteria,1V1Q2@1239|Firmicutes,4HFYS@91061|Bacilli,1ZFM6@1386|Bacillus 91061|Bacilli S Lysine exporter protein LysE YggA argO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE HPHIIJEP_00870 224308.BSU10860 1.72e-120 343.0 COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes,4HIYI@91061|Bacilli,1ZJR9@1386|Bacillus 91061|Bacilli S DinB family yisT - - - - - - - - - - - DinB HPHIIJEP_00871 224308.BSU10850 1.36e-244 672.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HDFF@91061|Bacilli,1ZQC0@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain yisS GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019310,GO:0019751,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0048037,GO:0050662,GO:0050896,GO:0051287,GO:0051716,GO:0055114,GO:0070403,GO:0070404,GO:0070887,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902140,GO:1902141 1.1.1.18,1.1.1.369,1.1.1.370 ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951,R09953 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_00872 224308.BSU10840 1.83e-235 648.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,1ZQ1E@1386|Bacillus 91061|Bacilli K helix_turn _helix lactose operon repressor rbsR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 HPHIIJEP_00873 224308.BSU10830 1.65e-206 571.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UYDC@1239|Firmicutes,4HAAA@91061|Bacilli,1ZCW5@1386|Bacillus 91061|Bacilli K Transcriptional regulator yisR - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC HPHIIJEP_00874 224308.BSU10820 1.01e-310 848.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli,1ZBQK@1386|Bacillus 91061|Bacilli V Mate efflux family protein yisQ - - - - - - - - - - - MatE HPHIIJEP_00875 224308.BSU10810 2.86e-185 516.0 COG1562@1|root,COG1562@2|Bacteria,1TQHF@1239|Firmicutes,4HA1A@91061|Bacilli,1ZCIV@1386|Bacillus 91061|Bacilli I phytoene crtM - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY HPHIIJEP_00876 224308.BSU10800 1.07e-114 328.0 COG2318@1|root,COG2318@2|Bacteria,1V6ZG@1239|Firmicutes,4HJ60@91061|Bacilli,1ZDMN@1386|Bacillus 91061|Bacilli S Damage-inducible protein DinB yizA - - - - - - - - - - - DinB HPHIIJEP_00877 224308.BSU10790 0.0 1276.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HA44@91061|Bacilli,1ZBY8@1386|Bacillus 91061|Bacilli E Asparagine synthase asnO - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 HPHIIJEP_00878 224308.BSU10780 2.49e-130 370.0 2E4ZB@1|root,32ZT1@2|Bacteria,1VHAC@1239|Firmicutes,4HQBP@91061|Bacilli,1ZD5D@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2777) yisN - - - - - - - - - - - DUF2777 HPHIIJEP_00879 224308.BSU10770 0.0 1648.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,1ZAZE@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family wprA - - ko:K13274 - - - - ko00000,ko01000,ko01002,ko03110 - - - Peptidase_S8 HPHIIJEP_00880 224308.BSU10760 1.02e-74 224.0 2CKSS@1|root,32W2Q@2|Bacteria,1VB9W@1239|Firmicutes,4HMC5@91061|Bacilli,1ZHSY@1386|Bacillus 91061|Bacilli S UPF0344 protein yisL - - - - - - - - - - - DUF1516 HPHIIJEP_00881 224308.BSU10750 2.66e-219 604.0 COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus 91061|Bacilli Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) yisK - - - - - - - - - - - FAA_hydrolase HPHIIJEP_00882 224308.BSU10740 1.88e-222 613.0 COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus 91061|Bacilli M Spore Coat cotH - - ko:K06330 - - - - ko00000 - - - CotH HPHIIJEP_00883 224308.BSU10730 1.52e-32 112.0 2DJ46@1|root,304QH@2|Bacteria,1TX0U@1239|Firmicutes,4I5VT@91061|Bacilli,1ZJMR@1386|Bacillus 91061|Bacilli S Spo0E like sporulation regulatory protein yisI - - - - - - - - - - - SpoOE-like HPHIIJEP_00884 224308.BSU10720 1.82e-45 146.0 2DPJX@1|root,332FH@2|Bacteria,1VF9T@1239|Firmicutes,4HPCA@91061|Bacilli,1ZIV2@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA GO:0000003,GO:0008150,GO:0009847,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - ko:K06299 - - - - ko00000 - - - gerPA HPHIIJEP_00885 224308.BSU10710 1.76e-47 152.0 2EBHF@1|root,335HY@2|Bacteria,1VHMW@1239|Firmicutes,4HPZZ@91061|Bacilli,1ZIW2@1386|Bacillus 91061|Bacilli S cell differentiation gerPB - - ko:K06300 - - - - ko00000 - - - GerPB HPHIIJEP_00886 224308.BSU10700 3.34e-92 275.0 2EBJR@1|root,335K6@2|Bacteria,1VF1J@1239|Firmicutes,4HNKG@91061|Bacilli,1ZI2K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPC - - ko:K06301 - - - - ko00000 - - - GerPC HPHIIJEP_00887 224308.BSU10690 6.07e-33 114.0 2C5QJ@1|root,33C5U@2|Bacteria,1VK5Y@1239|Firmicutes,4HR2R@91061|Bacilli,1ZIUX@1386|Bacillus 91061|Bacilli S Spore germination protein gerPD - - ko:K06302 - - - - ko00000 - - - - HPHIIJEP_00888 224308.BSU10680 2.76e-86 254.0 2EEB8@1|root,3385J@2|Bacteria,1VM15@1239|Firmicutes,4HPJI@91061|Bacilli,1ZJ91@1386|Bacillus 91061|Bacilli S Spore germination protein GerPE gerPE - - ko:K06303 - - - - ko00000 - - - GerPE HPHIIJEP_00889 224308.BSU10670 3.3e-43 140.0 2DP0U@1|root,3302E@2|Bacteria,1VHZ7@1239|Firmicutes,4HNJQ@91061|Bacilli,1ZIWY@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF gerPF - - ko:K06299,ko:K06304 - - - - ko00000 - - - gerPA HPHIIJEP_00890 224308.BSU10660 2.61e-64 196.0 COG1403@1|root,COG1403@2|Bacteria,1VFR5@1239|Firmicutes,4HQB5@91061|Bacilli,1ZICY@1386|Bacillus 91061|Bacilli V COG1403 Restriction endonuclease yisB - - - - - - - - - - - HNH HPHIIJEP_00891 224308.BSU10650 0.0 1805.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,1ZAP5@1386|Bacillus 91061|Bacilli L COG0419 ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C HPHIIJEP_00892 224308.BSU10640 1.4e-280 767.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,1ZBQQ@1386|Bacillus 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C HPHIIJEP_00893 224308.BSU10630 0.0 2399.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZBG6@1386|Bacillus 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C HPHIIJEP_00894 224308.BSU10620 0.0 2299.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,1ZC70@1386|Bacillus 91061|Bacilli L ATP-dependent helicase deoxyribonuclease subunit B rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C HPHIIJEP_00895 224308.BSU10610 9.3e-102 294.0 COG1633@1|root,COG1633@2|Bacteria,1V9AF@1239|Firmicutes,4HIP7@91061|Bacilli,1ZGFE@1386|Bacillus 91061|Bacilli S Rubrerythrin yhjR - - - - - - - - - - - DUF2202,Rubrerythrin HPHIIJEP_00896 224308.BSU10590 0.0 1147.0 COG4533@1|root,COG4533@2|Bacteria,1TRY2@1239|Firmicutes,4HBZ3@91061|Bacilli,1ZFQC@1386|Bacillus 91061|Bacilli S Sugar transport-related sRNA regulator N-term - GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - - - - - - - - - - SBP_bac_5,SgrR_N HPHIIJEP_00897 224308.BSU10580 8.2e-269 738.0 COG0477@1|root,COG0477@2|Bacteria,COG2814@2|Bacteria,1V1U3@1239|Firmicutes,4HBXY@91061|Bacilli,1ZQZT@1386|Bacillus 91061|Bacilli EGP Transmembrane secretion effector - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like HPHIIJEP_00898 224308.BSU10570 6.91e-243 671.0 COG3180@1|root,COG3180@2|Bacteria,1UVXN@1239|Firmicutes,4HDRW@91061|Bacilli,1ZDNB@1386|Bacillus 91061|Bacilli S membrane yhjN - - ko:K07120 - - - - ko00000 - - - AbrB HPHIIJEP_00899 224308.BSU10560 5.09e-238 654.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,1ZC0J@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhjM - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 HPHIIJEP_00900 224308.BSU10550 0.0 877.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HBZ8@91061|Bacilli,1ZCTS@1386|Bacillus 91061|Bacilli E Belongs to the DegT DnrJ EryC1 family - GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.104 ko:K18653 - - R10698 RC00006,RC00781 ko00000,ko01000 - - - DegT_DnrJ_EryC1 HPHIIJEP_00901 224308.BSU10540 8.81e-204 563.0 COG0561@1|root,COG0561@2|Bacteria,1V3E0@1239|Firmicutes,4HGK8@91061|Bacilli,1ZBFY@1386|Bacillus 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ntdB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017000,GO:0017144,GO:0042578,GO:0044237,GO:0044249 3.1.3.24,3.1.3.92 ko:K07024,ko:K18654 ko00500,map00500 - R00805,R06211 RC00017 ko00000,ko00001,ko01000 - - - S6PP HPHIIJEP_00902 224308.BSU10530 9.38e-256 701.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 1.1.1.18,1.1.1.361,1.1.1.369 ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_00903 224308.BSU10520 1.73e-269 740.0 COG0738@1|root,COG0738@2|Bacteria,1V2RZ@1239|Firmicutes,4I0M2@91061|Bacilli,1ZFFY@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily glcP - - ko:K08174 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 HPHIIJEP_00906 224308.BSU10510 1.63e-121 347.0 COG1846@1|root,COG1846@2|Bacteria,1VXUD@1239|Firmicutes,4HXW7@91061|Bacilli,1ZJI1@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein yhjH - - - - - - - - - - - MarR HPHIIJEP_00907 224308.BSU10500 0.0 964.0 COG0654@1|root,COG0654@2|Bacteria,1TSDI@1239|Firmicutes,4HAQG@91061|Bacilli,1ZF6C@1386|Bacillus 91061|Bacilli CH FAD binding domain yhjG - - - - - - - - - - - FAD_binding_3 HPHIIJEP_00908 224308.BSU10490 3.09e-118 338.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZAPC@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family spsB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 HPHIIJEP_00909 224308.BSU10480 5.69e-140 396.0 COG0398@1|root,COG0398@2|Bacteria,1TS5T@1239|Firmicutes,4HDKU@91061|Bacilli,1ZCHZ@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein yhjE - - - - - - - - - - - SNARE_assoc HPHIIJEP_00910 224308.BSU10470 4.13e-78 233.0 2ATJK@1|root,31J3N@2|Bacteria,1V8E1@1239|Firmicutes,4HK5R@91061|Bacilli,1ZH24@1386|Bacillus 91061|Bacilli - - yhjD - - - - - - - - - - - - HPHIIJEP_00911 224308.BSU10460 1.61e-36 123.0 2EFSS@1|root,339IS@2|Bacteria,1VMRC@1239|Firmicutes,4HR88@91061|Bacilli,1ZKA6@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3311) yhjC - - - - - - - - - - - DUF3311 HPHIIJEP_00912 224308.BSU10450 0.0 908.0 COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli,1ZCBN@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yhjB - - ko:K03307 - - - - ko00000 2.A.21 - - SSF HPHIIJEP_00913 224308.BSU10440 4.64e-53 167.0 2E52I@1|root,32ZVS@2|Bacteria,1VEXA@1239|Firmicutes,4HP05@91061|Bacilli,1ZJT0@1386|Bacillus 91061|Bacilli S Excalibur calcium-binding domain yhjA - - - - - - - - - - - Excalibur HPHIIJEP_00914 224308.BSU10430 6.01e-215 593.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZDFM@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase yhxD - - - - - - - - - - - adh_short_C2 HPHIIJEP_00915 224308.BSU10420 2.19e-141 398.0 COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,1ZGB4@1386|Bacillus 91061|Bacilli K Competence transcription factor comK - - ko:K02250 ko02024,map02024 - - - ko00000,ko00001,ko02044,ko03000 - - - ComK HPHIIJEP_00916 224308.BSU10410 8.1e-44 142.0 2EUKM@1|root,33N2I@2|Bacteria,1VP85@1239|Firmicutes,4HRNF@91061|Bacilli,1ZIVF@1386|Bacillus 91061|Bacilli S IDEAL yhzC - - - - - - - - - - - IDEAL HPHIIJEP_00917 224308.BSU10400 2.24e-203 563.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yhxC - - - - - - - - - - - adh_short_C2 HPHIIJEP_00918 224308.BSU10390 0.0 1029.0 COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,4H9V8@91061|Bacilli,1ZC19@1386|Bacillus 91061|Bacilli CE COG0665 Glycine D-amino acid oxidases (deaminating) yhfW GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - - - - - - - - - - DAO,Rieske HPHIIJEP_00919 224308.BSU10380 1.76e-258 714.0 COG0840@1|root,COG0840@2|Bacteria,1TRTV@1239|Firmicutes,4H9M1@91061|Bacilli,1ZBCT@1386|Bacillus 91061|Bacilli NT chemotaxis protein hemAT GO:0003674,GO:0005488,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0020037,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0046906,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:1901363 - ko:K06595 - - - - ko00000,ko02035 - - - MCPsignal,Protoglobin HPHIIJEP_00920 224308.BSU10370 1.47e-118 340.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,1ZC7W@1386|Bacillus 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY HPHIIJEP_00921 224308.BSU10360 0.0 953.0 COG0318@1|root,COG0318@2|Bacteria,1TT9C@1239|Firmicutes,4HBQ2@91061|Bacilli,1ZCW8@1386|Bacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain vraA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C HPHIIJEP_00922 224308.BSU10350 1.05e-250 689.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family yhfS - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N HPHIIJEP_00923 224308.BSU10340 3.23e-139 393.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,1ZDQW@1386|Bacillus 91061|Bacilli G Belongs to the phosphoglycerate mutase family yhfR - 5.4.2.12 ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 HPHIIJEP_00924 224308.BSU10330 3.23e-222 613.0 COG4594@1|root,COG4594@2|Bacteria,1VQVG@1239|Firmicutes,4HTU4@91061|Bacilli,1ZPXH@1386|Bacillus 91061|Bacilli M Periplasmic binding protein yhfQ GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 HPHIIJEP_00925 224308.BSU10320 1.33e-229 633.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,1ZCGD@1386|Bacillus 91061|Bacilli C Quinone oxidoreductase yhfP - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N HPHIIJEP_00926 224308.BSU10310 3.6e-101 293.0 COG0454@1|root,COG0456@2|Bacteria,1V3W3@1239|Firmicutes,4HHYX@91061|Bacilli,1ZGJE@1386|Bacillus 91061|Bacilli K acetyltransferase - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - - - - - - - - - - Acetyltransf_1 HPHIIJEP_00927 224308.BSU10300 1.98e-259 712.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family aprE GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 ko:K01342,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,Peptidase_S8,SLH HPHIIJEP_00928 224308.BSU10290 2.54e-303 827.0 COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus 91061|Bacilli O Peptidase M48 yhfN GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 - - - - - - - - - - Peptidase_M48,Peptidase_M48_N HPHIIJEP_00929 224308.BSU10280 2.28e-84 249.0 29RG4@1|root,30CIX@2|Bacteria,1U9Z4@1239|Firmicutes,4IK71@91061|Bacilli,1ZFIS@1386|Bacillus 91061|Bacilli - - yhfM - - - - - - - - - - - - HPHIIJEP_00930 224308.BSU10270 0.0 1034.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZPZU@1386|Bacillus 91061|Bacilli IQ AMP-binding enzyme C-terminal domain yhfL - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C HPHIIJEP_00931 224308.BSU10260 2.48e-142 402.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,1ZBH3@1386|Bacillus 91061|Bacilli GM NmrA-like family yhfK GO:0005575,GO:0005622,GO:0005623,GO:0044464 - - - - - - - - - - NAD_binding_10 HPHIIJEP_00932 224308.BSU10250 4.06e-245 672.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,1ZBIZ@1386|Bacillus 91061|Bacilli H Lipoate-protein ligase lplJ GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C HPHIIJEP_00933 224308.BSU10240 1.2e-182 507.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,1ZCZE@1386|Bacillus 91061|Bacilli S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 HPHIIJEP_00934 224308.BSU10220 4.77e-289 791.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 - iYO844.BSU10220 SDF HPHIIJEP_00935 224308.BSU10210 1.53e-93 273.0 COG4405@1|root,COG4405@2|Bacteria,1VDG5@1239|Firmicutes,4HM8P@91061|Bacilli,1ZKFH@1386|Bacillus 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH HPHIIJEP_00936 224308.BSU10200 1.55e-252 692.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,4HBDK@91061|Bacilli,1ZBP8@1386|Bacillus 91061|Bacilli G peptidase M42 yhfE - - - - - - - - - - - Peptidase_M42 HPHIIJEP_00937 224308.BSU10180 6.3e-176 491.0 COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli,1ZGJV@1386|Bacillus 91061|Bacilli S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 HPHIIJEP_00938 224308.BSU10170 3.57e-236 649.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,1ZD2T@1386|Bacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabHB GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C HPHIIJEP_00939 224308.BSU10160 0.0 936.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,1ZBH0@1386|Bacillus 91061|Bacilli S YhgE Pip N-terminal domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 HPHIIJEP_00940 224308.BSU10150 5.79e-132 374.0 COG1309@1|root,COG1309@2|Bacteria,1V2H2@1239|Firmicutes,4HHJD@91061|Bacilli,1ZFYK@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhgD GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N HPHIIJEP_00941 224308.BSU10140 0.0 925.0 COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,4HAUG@91061|Bacilli,1ZANK@1386|Bacillus 91061|Bacilli H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX hemY - 1.3.3.15,1.3.3.4 ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03222,R04178 RC00885 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09325 Amino_oxidase HPHIIJEP_00942 224308.BSU10130 3.99e-230 632.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,1ZAZ6@1386|Bacillus 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase HPHIIJEP_00943 224308.BSU10120 1.29e-259 711.0 COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,4HAXT@91061|Bacilli,1ZDGX@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III hemE GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D HPHIIJEP_00944 224308.BSU10110 0.0 1413.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase HPHIIJEP_00945 224308.BSU10100 1.31e-118 338.0 COG2329@1|root,COG2329@2|Bacteria,1V501@1239|Firmicutes,4HHA2@91061|Bacilli,1ZGDD@1386|Bacillus 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides traP GO:0005575,GO:0016020 1.14.99.57 ko:K21481 - - - - ko00000,ko01000 - - - ABM HPHIIJEP_00946 1051501.AYTL01000027_gene554 1e-44 147.0 COG1592@1|root,COG1592@2|Bacteria,1W59I@1239|Firmicutes,4I0MS@91061|Bacilli,1ZSGB@1386|Bacillus 91061|Bacilli C Rubrerythrin - - - - - - - - - - - - - HPHIIJEP_00947 224308.BSU10080 1.28e-310 849.0 COG3069@1|root,COG3069@2|Bacteria,1TQ99@1239|Firmicutes,4H9Q2@91061|Bacilli,1ZCNB@1386|Bacillus 91061|Bacilli C membrane yhfA - - - - - - - - - - - - HPHIIJEP_00948 224308.BSU10070 5.37e-292 796.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZAR7@1386|Bacillus 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase yhaA - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HPHIIJEP_00949 224308.BSU10060 2.89e-161 452.0 28I6D@1|root,2Z89E@2|Bacteria,1TQNW@1239|Firmicutes,4HCGQ@91061|Bacilli,1ZAQM@1386|Bacillus 91061|Bacilli S EcsC protein family ecsC - - - - - - - - - - - EcsC HPHIIJEP_00950 224308.BSU10050 3.11e-272 747.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,1ZBQG@1386|Bacillus 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB HPHIIJEP_00951 224308.BSU10040 2.7e-176 491.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZBAI@1386|Bacillus 91061|Bacilli V transporter (ATP-binding protein) ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_00952 224308.BSU10030 3.5e-106 305.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,1ZGI0@1386|Bacillus 91061|Bacilli FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT HPHIIJEP_00953 224308.BSU10020 2.06e-259 711.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1ZB9N@1386|Bacillus 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 HPHIIJEP_00954 224308.BSU10010 6.32e-104 302.0 2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,4HHGS@91061|Bacilli,1ZF8Y@1386|Bacillus 91061|Bacilli S Tryptophan transporter TrpP trpP - - - - - - - - - - iYO844.BSU10010 TrpP HPHIIJEP_00955 720555.BATR1942_02630 9.66e-30 106.0 2BAXH@1|root,324D7@2|Bacteria,1UARY@1239|Firmicutes,4IM4R@91061|Bacilli,1ZJ5E@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_00956 224308.BSU10000 3.89e-54 172.0 COG4980@1|root,COG4980@2|Bacteria,1VAKP@1239|Firmicutes,4HKD5@91061|Bacilli,1ZJ3D@1386|Bacillus 91061|Bacilli S YtxH-like protein yhaH - - - - - - - - - - - YtxH HPHIIJEP_00957 224308.BSU09990 4.92e-148 416.0 COG1846@1|root,COG1846@2|Bacteria,1UY04@1239|Firmicutes,4HBQS@91061|Bacilli,1ZBRK@1386|Bacillus 91061|Bacilli K Negative regulator of protease production and sporulation hpr GO:0000003,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K09682 - - - - ko00000,ko03000 - - - MarR HPHIIJEP_00958 224308.BSU09980 8.48e-73 218.0 2D8K4@1|root,32TRG@2|Bacteria,1VCG9@1239|Firmicutes,4HMCV@91061|Bacilli,1ZJ2C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1878) yhaI - - - - - - - - - - - DUF1878 HPHIIJEP_00959 224308.BSU09965 1.4e-116 334.0 293PD@1|root,2ZR52@2|Bacteria,1V3PX@1239|Firmicutes,4HI32@91061|Bacilli,1ZFA0@1386|Bacillus 91061|Bacilli S Putative zincin peptidase yhaK - - - - - - - - - - - DUF3267 HPHIIJEP_00960 224308.BSU09950 6.9e-160 453.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,1ZC6P@1386|Bacillus 91061|Bacilli M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA - 5.2.1.8 ko:K01802,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase_3,Trigger_C HPHIIJEP_00961 224308.BSU09940 1.88e-39 131.0 2DQFN@1|root,336J9@2|Bacteria,1VJ6N@1239|Firmicutes,4HQ0A@91061|Bacilli,1ZK3U@1386|Bacillus 91061|Bacilli S Sporulation protein YhaL yhaL - - - - - - - - - - - Spore_YhaL HPHIIJEP_00962 224308.BSU09930 5.22e-228 627.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,1ZB1G@1386|Bacillus 91061|Bacilli L Shows a 3'-5' exoribonuclease activity yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon HPHIIJEP_00963 224308.BSU09920 0.0 1783.0 COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,1ZDHB@1386|Bacillus 91061|Bacilli L AAA domain yhaN - - - - - - - - - - - AAA_27 HPHIIJEP_00964 224308.BSU09910 2.71e-300 818.0 COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,4HCA0@91061|Bacilli,1ZC5G@1386|Bacillus 91061|Bacilli L DNA repair exonuclease yhaO - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,Metallophos_2 HPHIIJEP_00965 224308.BSU09900 5.14e-272 748.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,1ZBM6@1386|Bacillus 91061|Bacilli CP COG1668 ABC-type Na efflux pump, permease component yhaP - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 HPHIIJEP_00966 224308.BSU09890 1.86e-213 589.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,1ZC9T@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yhaQ - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 HPHIIJEP_00967 224308.BSU09889 9.36e-36 121.0 2E4GP@1|root,32ZBV@2|Bacteria,1VF2A@1239|Firmicutes,4HNUS@91061|Bacilli,1ZIT1@1386|Bacillus 91061|Bacilli S YhzD-like protein - - - - - - - - - - - - YhzD HPHIIJEP_00968 224308.BSU09880 1.79e-169 474.0 COG1024@1|root,COG1024@2|Bacteria,1TRCQ@1239|Firmicutes,4HDUU@91061|Bacilli,1ZARB@1386|Bacillus 91061|Bacilli I enoyl-CoA hydratase yhaR - - - - - - - - - - - ECH_1 HPHIIJEP_00970 224308.BSU09860 1.87e-113 325.0 COG0490@1|root,COG0490@2|Bacteria,1V544@1239|Firmicutes,4HIGC@91061|Bacilli,1ZR77@1386|Bacillus 91061|Bacilli P regulatory, ligand-binding protein related to C-terminal domains of K channels - - - ko:K07228 - - - - ko00000 - - - TrkA_C HPHIIJEP_00971 224308.BSU09850 1.85e-267 735.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HC99@91061|Bacilli,1ZBQT@1386|Bacillus 91061|Bacilli P COG0475 Kef-type K transport systems, membrane components yhaU - - ko:K03455 - - - - ko00000 2.A.37 - iYO844.BSU09850 Na_H_Exchanger HPHIIJEP_00972 224308.BSU09840 0.0 1006.0 COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,4HC2D@91061|Bacilli,1ZCRB@1386|Bacillus 91061|Bacilli H coproporphyrinogen III oxidase hemZ - - - - - - - - - - - Radical_SAM HPHIIJEP_00973 1051501.AYTL01000027_gene524 2.14e-198 550.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,1ZQ4F@1386|Bacillus 91061|Bacilli S haloacid dehalogenase-like hydrolase yhaX - - - - - - - - - - - Hydrolase_3 HPHIIJEP_00974 224308.BSU09810 1.29e-261 716.0 COG4335@1|root,COG4335@2|Bacteria,1TRE4@1239|Firmicutes,4HA0G@91061|Bacilli,1ZBAW@1386|Bacillus 91061|Bacilli L DNA alkylation repair enzyme yhaZ - - - - - - - - - - - DNA_alkylation HPHIIJEP_00975 224308.BSU09800 7.46e-72 216.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HKKC@91061|Bacilli,1ZH14@1386|Bacillus 91061|Bacilli S Belongs to the UPF0342 family yheA - - - - - - - - - - - Com_YlbF HPHIIJEP_00976 224308.BSU09790 7.19e-260 713.0 COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1ZB1W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0754 family yheB - - - - - - - - - - - DUF445 HPHIIJEP_00977 224308.BSU09780 1.32e-273 747.0 COG0189@1|root,COG0189@2|Bacteria,1U4ME@1239|Firmicutes,4HFD2@91061|Bacilli,1ZBNP@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheC - - - - - - - - - - - ATPgrasp_YheCD HPHIIJEP_00978 224308.BSU09770 0.0 921.0 COG0189@1|root,COG0189@2|Bacteria,1TSWS@1239|Firmicutes,4HCJA@91061|Bacilli,1ZAR6@1386|Bacillus 91061|Bacilli HJ YheC/D like ATP-grasp yheD GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - ATPgrasp_YheCD HPHIIJEP_00979 224308.BSU09760 2.27e-49 156.0 2E3WD@1|root,32YTI@2|Bacteria,1VGKG@1239|Firmicutes,4HSKD@91061|Bacilli,1ZIY3@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5342) yheE - - - - - - - - - - - DUF5342 HPHIIJEP_00980 224308.BSU09750 1.25e-38 129.0 2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus 91061|Bacilli S spore protein sspB - - ko:K06418,ko:K06419,ko:K06420 - - - - ko00000 - - - SASP HPHIIJEP_00981 224308.BSU09730 9.1e-141 398.0 COG0702@1|root,COG0702@2|Bacteria,1TS7J@1239|Firmicutes,4HFT3@91061|Bacilli,1ZGA3@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yheG - - - - - - - - - - - NAD_binding_10 HPHIIJEP_00982 224308.BSU09720 0.0 1287.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_00983 224308.BSU09710 0.0 1129.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBXB@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yheI - - ko:K18216,ko:K18889 ko02010,map02010 M00635,M00707 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran HPHIIJEP_00984 224308.BSU09690 9.07e-108 312.0 COG0589@1|root,COG0589@2|Bacteria,1V6RY@1239|Firmicutes,4HIZM@91061|Bacilli,1ZHCT@1386|Bacillus 91061|Bacilli T Belongs to the universal stress protein A family nhaX - - - - - - - - - - - Usp HPHIIJEP_00985 224308.BSU09680 1.47e-302 828.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter nhaC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter HPHIIJEP_00986 224308.BSU09670 1.91e-196 545.0 COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,1ZBVX@1386|Bacillus 91061|Bacilli E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 HPHIIJEP_00987 224308.BSU09660 5.7e-200 554.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HEQR@91061|Bacilli,1ZEGM@1386|Bacillus 91061|Bacilli G deacetylase nodB1 GO:0005575,GO:0016020 - - - - - - - - - - Cu_amine_oxidN1,Polysacc_deac_1 HPHIIJEP_00988 224308.BSU09650 1.39e-178 497.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HC4I@91061|Bacilli,1ZB8T@1386|Bacillus 91061|Bacilli K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 HPHIIJEP_00989 224308.BSU09640 1.06e-258 710.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HBDU@91061|Bacilli,1ZBUJ@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel yhdY - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel HPHIIJEP_00990 279010.BL02878 3.7e-09 52.4 2BH1X@1|root,32B2D@2|Bacteria,1UB36@1239|Firmicutes,4IMFW@91061|Bacilli,1ZK2I@1386|Bacillus 91061|Bacilli S Uncharacterized protein YhdX yhdX - - - - - - - - - - - yhdX HPHIIJEP_00991 224308.BSU09620 1.05e-171 479.0 COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase yhdW - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD HPHIIJEP_00992 224308.BSU09610 3.94e-85 251.0 COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4HNI0@91061|Bacilli,1ZJ3M@1386|Bacillus 91061|Bacilli D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB HPHIIJEP_00993 224308.BSU09600 5.01e-66 202.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,1ZIV0@1386|Bacillus 91061|Bacilli D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB HPHIIJEP_00994 224308.BSU09590 0.0 874.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBQF@1386|Bacillus 91061|Bacilli P COG1253 Hemolysins and related proteins containing CBS domains yhdT - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HPHIIJEP_00995 224308.BSU09570 9.86e-282 770.0 COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,4HFCH@91061|Bacilli,1ZEW4@1386|Bacillus 91061|Bacilli E Aminotransferase yhdR - 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_00996 224308.BSU09560 3.44e-97 284.0 COG0789@1|root,COG0789@2|Bacteria,1VHZ2@1239|Firmicutes,4HMJ6@91061|Bacilli,1ZHVY@1386|Bacillus 91061|Bacilli K transcriptional cueR - - ko:K11923 - - - - ko00000,ko03000 - - - MerR_1 HPHIIJEP_00997 224308.BSU09550 2.18e-304 832.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HPHIIJEP_00998 224308.BSU09540 3.9e-143 403.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,1ZQCA@1386|Bacillus 91061|Bacilli I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase HPHIIJEP_00999 224308.BSU09530 1.93e-243 668.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,1ZFDQ@1386|Bacillus 91061|Bacilli C Aldo keto reductase yhdN - - - - - - - - - - - Aldo_ket_red HPHIIJEP_01000 224308.BSU09520 3.24e-113 325.0 COG1595@1|root,COG1595@2|Bacteria,1VYEJ@1239|Firmicutes,4IPY8@91061|Bacilli,1ZGTR@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigM - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01001 224308.BSU09510 6.13e-258 707.0 2C5RJ@1|root,2Z96W@2|Bacteria,1USSJ@1239|Firmicutes,4IRP8@91061|Bacilli,1ZRWA@1386|Bacillus 91061|Bacilli S Sigma factor regulator N-terminal yhdL - - - - - - - - - - - Sigma_reg_C,Sigma_reg_N,zf-HC2 HPHIIJEP_01002 224308.BSU09500 4.27e-59 182.0 29RMT@1|root,30CR2@2|Bacteria,1UA8R@1239|Firmicutes,4IKK7@91061|Bacilli,1ZH64@1386|Bacillus 91061|Bacilli S Sigma-M inhibitor protein yhdK - - - - - - - - - - - YhdK HPHIIJEP_01003 224308.BSU09490 1.75e-100 291.0 COG0454@1|root,COG0456@2|Bacteria,1V47B@1239|Firmicutes,4HHAS@91061|Bacilli,1ZI27@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - - - - - - - - - - Acetyltransf_1 HPHIIJEP_01004 224308.BSU09480 0.0 934.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,1ZB5R@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydeL - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR HPHIIJEP_01005 224308.BSU09470 1.01e-308 843.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family yhdH - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF HPHIIJEP_01006 224308.BSU09460 2.15e-315 861.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,1ZBB0@1386|Bacillus 91061|Bacilli E amino acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 HPHIIJEP_01007 224308.BSU09450 5.51e-206 570.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yhdF - - - - - - - - - - - adh_short_C2 HPHIIJEP_01008 224308.BSU09440 1.06e-260 714.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4HDG0@91061|Bacilli,1ZBE9@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt HPHIIJEP_01009 224308.BSU09430 4.93e-210 580.0 COG0583@1|root,COG0583@2|Bacteria,1V1MH@1239|Firmicutes,4HFVE@91061|Bacilli,1ZD99@1386|Bacillus 91061|Bacilli K Transcriptional regulator citR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K19242 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_01010 224308.BSU09420 1.45e-203 567.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat lytE - - ko:K19220,ko:K19223,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60 HPHIIJEP_01011 224308.BSU09410 0.0 897.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase HPHIIJEP_01012 224308.BSU09400 0.0 953.0 COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,4HBAW@91061|Bacilli,1ZAT5@1386|Bacillus 91061|Bacilli S Stage V sporulation protein R spoVR - - ko:K06415 - - - - ko00000 - - - SpoVR HPHIIJEP_01013 224308.BSU09390 2.38e-303 836.0 COG0668@1|root,COG0668@2|Bacteria,1TQXJ@1239|Firmicutes,4HCK2@91061|Bacilli,1ZF3F@1386|Bacillus 91061|Bacilli M Conserved TM helix ygxB - - - - - - - - - - - TM_helix HPHIIJEP_01014 224308.BSU09380 5.58e-99 287.0 COG1959@1|root,COG1959@2|Bacteria,1V4G2@1239|Firmicutes,4HHBH@91061|Bacilli,1ZH5D@1386|Bacillus 91061|Bacilli K Transcriptional regulator nsrR - - ko:K13771 ko05132,map05132 - - - ko00000,ko00001,ko03000 - - - Rrf2 HPHIIJEP_01015 224308.BSU09370 5.63e-274 758.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat lytF - - ko:K19220,ko:K19223,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60 HPHIIJEP_01016 224308.BSU09360 3.57e-72 216.0 29RSF@1|root,30CW8@2|Bacteria,1UAGC@1239|Firmicutes,4IKUT@91061|Bacilli,1ZHQ6@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3889) yhdC - - - - - - - - - - - DUF3889 HPHIIJEP_01017 224308.BSU09350 1.65e-51 162.0 2E2U4@1|root,32XW8@2|Bacteria,1VAT9@1239|Firmicutes,4HN53@91061|Bacilli,1ZHZK@1386|Bacillus 91061|Bacilli S YhdB-like protein yhdB - - - - - - - - - - - YhdB HPHIIJEP_01018 224308.BSU09340 4.67e-116 333.0 COG0431@1|root,COG0431@2|Bacteria,1VDZQ@1239|Firmicutes,4HMQ1@91061|Bacilli,1ZQ9A@1386|Bacillus 91061|Bacilli S NADPH-dependent FMN reductase yhdA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0052873,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.7.1.6 ko:K03206 - - - - ko00000,ko01000 - - - FMN_red HPHIIJEP_01019 224308.BSU09330 5.22e-142 402.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yhcZ - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg HPHIIJEP_01020 224308.BSU09320 1.88e-272 745.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TR88@1239|Firmicutes,4HBF3@91061|Bacilli,1ZCMJ@1386|Bacillus 91061|Bacilli T Histidine kinase yhcY - 2.7.13.3 ko:K02480 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA_3 HPHIIJEP_01021 224308.BSU09310 0.0 1126.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,1ZBEM@1386|Bacillus 91061|Bacilli G Phosphoglucomutase pgcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV HPHIIJEP_01022 224308.BSU09300 0.0 1106.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,1ZCGN@1386|Bacillus 91061|Bacilli C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C HPHIIJEP_01023 224308.BSU09290 0.0 1002.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1ZB20@1386|Bacillus 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N HPHIIJEP_01024 224308.BSU09280 1.34e-194 540.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,1ZCUB@1386|Bacillus 91061|Bacilli G Belongs to the MIP aquaporin (TC 1.A.8) family glpF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP HPHIIJEP_01025 224308.BSU09270 6.25e-134 379.0 COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,4HH9Q@91061|Bacilli,1ZCJN@1386|Bacillus 91061|Bacilli K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA glpP GO:0001072,GO:0001678,GO:0003674,GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009743,GO:0009746,GO:0009749,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0019400,GO:0019725,GO:0019751,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0033500,GO:0034284,GO:0042221,GO:0042592,GO:0042593,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046677,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0055082,GO:0060255,GO:0060567,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071704,GO:0080090,GO:0140110,GO:1901615,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - ko:K02443 - - - - ko00000,ko03000 - - - G3P_antiterm HPHIIJEP_01026 224308.BSU09260 0.0 900.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HAA5@91061|Bacilli,1ZAUQ@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family yhxA - - - - - - - - - - - Aminotran_3 HPHIIJEP_01027 224308.BSU09250 0.0 1042.0 COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus 91061|Bacilli K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase yhcX - - - - - - - - - - - Acetyltransf_1,CN_hydrolase HPHIIJEP_01028 224308.BSU09240 2.5e-154 433.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,1ZEV6@1386|Bacillus 91061|Bacilli S hydrolase yhcW GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - ko:K07025 - - - - ko00000 - - - HAD_2 HPHIIJEP_01029 224308.BSU09230 1.76e-90 265.0 COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4ISB2@91061|Bacilli,1ZS4F@1386|Bacillus 91061|Bacilli S COG0517 FOG CBS domain yhcV - - - - - - - - - - - CBS HPHIIJEP_01030 224308.BSU09220 2.47e-88 259.0 29RAQ@1|root,30CCF@2|Bacteria,1U9MH@1239|Firmicutes,4IJSY@91061|Bacilli,1ZG4U@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5365) yhcU - - - - - - - - - - - DUF5365 HPHIIJEP_01031 224308.BSU09210 1.67e-218 602.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,1ZDMG@1386|Bacillus 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 HPHIIJEP_01032 224308.BSU09200 2.53e-134 381.0 COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus 91061|Bacilli M COG3764 Sortase (surface protein transpeptidase) yhcS - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase HPHIIJEP_01033 224308.BSU09190 0.0 2260.0 COG0737@1|root,COG1525@1|root,COG4085@1|root,COG0737@2|Bacteria,COG1525@2|Bacteria,COG4085@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yhcR - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - iYO844.BSU07840 5_nucleotid_C,Gram_pos_anchor,LTD,Metallophos,SLH,SNase HPHIIJEP_01034 224308.BSU09180 1.68e-146 413.0 COG5577@1|root,COG5577@2|Bacteria,1UIAR@1239|Firmicutes,4HC0T@91061|Bacilli,1ZDQK@1386|Bacillus 91061|Bacilli M Spore coat protein yhcQ - - - - - - - - - - - Coat_F HPHIIJEP_01035 224308.BSU09165 3.12e-224 619.0 2AJCZ@1|root,319YD@2|Bacteria,1V9QT@1239|Firmicutes,4IIN1@91061|Bacilli,1ZDEB@1386|Bacillus 91061|Bacilli - - yhcP - - - - - - - - - - - - HPHIIJEP_01036 224308.BSU09150 3.47e-103 301.0 2DZ9Y@1|root,32V70@2|Bacteria,1VA6H@1239|Firmicutes,4HKSG@91061|Bacilli,1ZHSJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yhcN - - - - - - - - - - - Spore_YhcN_YlaJ HPHIIJEP_01037 224308.BSU09140 3.63e-60 189.0 29RHY@1|root,30CKX@2|Bacteria,1UA2I@1239|Firmicutes,4IKBT@91061|Bacilli,1ZGD7@1386|Bacillus 91061|Bacilli - - yhcM - - - - - - - - - - - - HPHIIJEP_01038 1227360.C176_11948 3.22e-65 199.0 COG1695@1|root,COG1695@2|Bacteria,1VANP@1239|Firmicutes,4HKRZ@91061|Bacilli,26FS0@186818|Planococcaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - - - - - - - - - - PadR HPHIIJEP_01039 326423.RBAM_005500 1.69e-114 330.0 28PQ5@1|root,2ZCCA@2|Bacteria,1V1RW@1239|Firmicutes,4HGAM@91061|Bacilli,1ZFQB@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2812) - - - - - - - - - - - - DUF2812 HPHIIJEP_01040 224308.BSU09130 2.62e-301 825.0 COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,4HAJY@91061|Bacilli,1ZB7C@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family tcyP - - ko:K06956 - - - - ko00000 - - - SDF HPHIIJEP_01041 224308.BSU09120 3.36e-249 685.0 COG2199@1|root,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,4HEDD@91061|Bacilli,1ZB59@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain yhcK - 2.7.7.65 ko:K18967 - - - - ko00000,ko01000,ko02000 9.B.34.1.1 - - 5TM-5TMR_LYT,GAF_2,GGDEF HPHIIJEP_01042 224308.BSU09110 2.13e-192 534.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,1ZB4Z@1386|Bacillus 91061|Bacilli M Belongs to the nlpA lipoprotein family metQ_3 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 HPHIIJEP_01043 224308.BSU09100 1.91e-42 138.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHTU@1386|Bacillus 91061|Bacilli K Cold-shock protein cspB GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03704 - - - - ko00000,ko03000 - - - CSD HPHIIJEP_01044 224308.BSU09090 9.87e-212 586.0 COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yhcI - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 HPHIIJEP_01045 224308.BSU09080 3.59e-210 582.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yhcH - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01046 224308.BSU09070 3.24e-156 439.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,1ZCBF@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yhcG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01047 224308.BSU09060 1.67e-79 236.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,1ZHSQ@1386|Bacillus 91061|Bacilli K Transcriptional regulator yhcF - - ko:K07979 - - - - ko00000,ko03000 - - - GntR HPHIIJEP_01048 720555.BATR1942_02120 2.06e-69 221.0 2CHZZ@1|root,32S6Y@2|Bacteria,1VA01@1239|Firmicutes,4IJSI@91061|Bacilli,1ZJVW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01050 224308.BSU09030 3.95e-59 185.0 28XRM@1|root,2ZJN4@2|Bacteria,1W210@1239|Firmicutes,4I1DZ@91061|Bacilli,1ZKKM@1386|Bacillus 91061|Bacilli - - yhcC - - - - - - - - - - - - HPHIIJEP_01051 224308.BSU09020 4.87e-128 363.0 COG0655@1|root,COG0655@2|Bacteria,1TSY9@1239|Firmicutes,4H9MQ@91061|Bacilli,1ZBKC@1386|Bacillus 91061|Bacilli S Belongs to the WrbA family yhcB GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 ko:K03809 ko00130,ko01110,map00130,map01110 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - FMN_red HPHIIJEP_01052 224308.BSU09010 0.0 997.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily yhcA - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 HPHIIJEP_01053 224308.BSU09000 2.67e-133 380.0 COG1566@1|root,COG1566@2|Bacteria,1V1F5@1239|Firmicutes,4HHAT@91061|Bacilli,1ZE85@1386|Bacillus 91061|Bacilli V COG1566 Multidrug resistance efflux pump yhbJ - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 HPHIIJEP_01054 224308.BSU08990 1.29e-101 295.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity yhbI GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K15973 - - - - ko00000,ko03000 - - - MarR HPHIIJEP_01055 224308.BSU08980 1.21e-286 782.0 COG2718@1|root,COG2718@2|Bacteria,1TQIN@1239|Firmicutes,4HBIH@91061|Bacilli,1ZATH@1386|Bacillus 91061|Bacilli S Belongs to the UPF0229 family yhbH - - ko:K09786 - - - - ko00000 - - - DUF444 HPHIIJEP_01056 224308.BSU08970 0.0 1226.0 COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,4HA8A@91061|Bacilli,1ZBM9@1386|Bacillus 91061|Bacilli T Ser protein kinase prkA - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA HPHIIJEP_01057 224308.BSU08960 1.29e-106 314.0 COG1664@1|root,COG1664@2|Bacteria,1V6FF@1239|Firmicutes,4HJV2@91061|Bacilli,1ZGKZ@1386|Bacillus 91061|Bacilli M COG1664 Integral membrane protein CcmA involved in cell shape determination yhbF - - - - - - - - - - - Bactofilin HPHIIJEP_01058 224308.BSU08950 1.32e-95 286.0 COG1664@1|root,COG1664@2|Bacteria,1V6E6@1239|Firmicutes,4HHZU@91061|Bacilli,1ZQYV@1386|Bacillus 91061|Bacilli M COG1664 Integral membrane protein CcmA involved in cell shape determination yhbE - - - - - - - - - - - Bactofilin HPHIIJEP_01059 224308.BSU08940 3.4e-143 405.0 COG0789@1|root,COG0789@2|Bacteria,1UYCQ@1239|Firmicutes,4HI3I@91061|Bacilli,1ZEDR@1386|Bacillus 91061|Bacilli K Protein of unknown function (DUF4004) yhbD - - - - - - - - - - - DUF4004 HPHIIJEP_01060 224308.BSU08930 6.53e-113 323.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,1ZFKH@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase HPHIIJEP_01061 224308.BSU08920 2.77e-225 620.0 2DB72@1|root,2Z7JI@2|Bacteria,1UR4B@1239|Firmicutes,4HCE4@91061|Bacilli,1ZC8T@1386|Bacillus 91061|Bacilli S Putative amidase domain yhbB - - - - - - - - - - - Amidase_6 HPHIIJEP_01062 224308.BSU08910 1.32e-276 756.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,1ZC1W@1386|Bacillus 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 HPHIIJEP_01063 224308.BSU08900 6.43e-146 411.0 COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,4HGDN@91061|Bacilli,1ZBT2@1386|Bacillus 91061|Bacilli S B3/4 domain yhzB - - - - - - - - - - - B3_4 HPHIIJEP_01065 224308.BSU08899 1.48e-39 131.0 COG1476@1|root,COG1476@2|Bacteria,1VCMF@1239|Firmicutes,4HQAM@91061|Bacilli,1ZJDE@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 HPHIIJEP_01066 224308.BSU08890 5.19e-98 286.0 2BYG6@1|root,33MFH@2|Bacteria,1VKUT@1239|Firmicutes,4HS20@91061|Bacilli,1ZJNY@1386|Bacillus 91061|Bacilli - - ygaO - - - - - - - - - - - - HPHIIJEP_01067 224308.BSU08880 4.82e-55 172.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,1ZHU3@1386|Bacillus 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 HPHIIJEP_01069 224308.BSU08860 9.35e-276 753.0 COG2141@1|root,COG2141@2|Bacteria,1TW8W@1239|Firmicutes,4HB95@91061|Bacilli,1ZCMH@1386|Bacillus 91061|Bacilli C Catalyzes the desulfonation of aliphatic sulfonates ssuD - 1.14.14.28,1.14.14.5 ko:K04091,ko:K20938 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase HPHIIJEP_01070 224308.BSU08850 8.33e-190 528.0 COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,1ZBH6@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ssuC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K15554 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - BPD_transp_1 HPHIIJEP_01071 224308.BSU08840 2.08e-218 605.0 COG0715@1|root,COG0715@2|Bacteria,1TRET@1239|Firmicutes,4IPY7@91061|Bacilli,1ZREQ@1386|Bacillus 91061|Bacilli M Sulfonate ABC transporter ssuA GO:0003674,GO:0005215 - ko:K15553 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - NMT1 HPHIIJEP_01072 224308.BSU08830 9.01e-179 498.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HAJC@91061|Bacilli,1ZCC8@1386|Bacillus 91061|Bacilli P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component ssuB GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - iYO844.BSU08830 ABC_tran HPHIIJEP_01073 224308.BSU08820 0.0 993.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katA GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel HPHIIJEP_01075 224308.BSU08790 0.0 1194.0 COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli,1ZBCQ@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU08790 ThiC-associated,ThiC_Rad_SAM HPHIIJEP_01076 224308.BSU08780 2.47e-162 454.0 COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,1ZC4Z@1386|Bacillus 91061|Bacilli E Belongs to the peptidase S51 family ygaJ GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 HPHIIJEP_01077 224308.BSU08770 1.58e-36 123.0 29SG5@1|root,30DM3@2|Bacteria,1UBEU@1239|Firmicutes,4IMTF@91061|Bacilli,1ZKT6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01078 224308.BSU08760 1.5e-183 510.0 COG4326@1|root,COG4326@2|Bacteria,1TPEA@1239|Firmicutes,4HBPW@91061|Bacilli,1ZBFU@1386|Bacillus 91061|Bacilli S COG4326 Sporulation control protein spo0M - - ko:K06377 - - - - ko00000 - - - Spo0M HPHIIJEP_01095 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01096 224308.BSU08750 8.23e-215 592.0 28IXS@1|root,2Z8VM@2|Bacteria,1TR3A@1239|Firmicutes,4HDYI@91061|Bacilli,1ZB0T@1386|Bacillus 91061|Bacilli S Nucleotidyltransferase-like ygxA - - - - - - - - - - - NTF-like HPHIIJEP_01097 224308.BSU08740 5.46e-74 222.0 2C1CK@1|root,313Y4@2|Bacteria,1V6FR@1239|Firmicutes,4HIGI@91061|Bacilli,1ZGXQ@1386|Bacillus 91061|Bacilli S UPF0295 protein ygzB - - - - - - - - - - - DUF2614 HPHIIJEP_01098 224308.BSU08730 2.37e-104 301.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,1ZFKE@1386|Bacillus 91061|Bacilli P Belongs to the Fur family perR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K09825 - - - - ko00000,ko03000 - - - FUR HPHIIJEP_01099 224308.BSU08720 1.69e-112 322.0 COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,1ZFKU@1386|Bacillus 91061|Bacilli O Peroxiredoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA HPHIIJEP_01100 224308.BSU08710 3.26e-312 850.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HBDZ@91061|Bacilli,1ZB74@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase gsaB - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU08710 Aminotran_3 HPHIIJEP_01101 224308.BSU08700 1.08e-237 656.0 COG4129@1|root,COG4129@2|Bacteria,1TPVH@1239|Firmicutes,4HAEG@91061|Bacilli,1ZCJA@1386|Bacillus 91061|Bacilli S Membrane ygaE - - - - - - - - - - - ArAE_1 HPHIIJEP_01102 224308.BSU08690 0.0 1098.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZAY7@1386|Bacillus 91061|Bacilli V ABC transporter ygaD GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran HPHIIJEP_01103 1051501.AYTL01000029_gene1545 8.1e-136 383.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,1ZB2J@1386|Bacillus 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 HPHIIJEP_01104 224308.BSU08670 8.96e-62 190.0 29NRW@1|root,309PW@2|Bacteria,1U5GK@1239|Firmicutes,4IF7D@91061|Bacilli,1ZIZN@1386|Bacillus 91061|Bacilli S YgaB-like protein ygaB - - - - - - - - - - - YgaB HPHIIJEP_01105 224308.BSU08660 2.35e-14 68.9 2DRQR@1|root,33CNQ@2|Bacteria,1VGGC@1239|Firmicutes,4HR2A@91061|Bacilli,1ZJ1V@1386|Bacillus 91061|Bacilli S Small, acid-soluble spore protein, gamma-type sspE - - ko:K06422 - - - - ko00000 - - - SASP_gamma HPHIIJEP_01106 224308.BSU08650 3.13e-172 481.0 COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,1ZAXT@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) fabL GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HPHIIJEP_01107 224308.BSU08640 1.42e-47 152.0 2BX0I@1|root,335P2@2|Bacteria,1VGI6@1239|Firmicutes,4HQNB@91061|Bacilli,1ZHXH@1386|Bacillus 91061|Bacilli - - yfhS - - - - - - - - - - - - HPHIIJEP_01108 224308.BSU08630 1.99e-266 732.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus 91061|Bacilli L A G-specific mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 HPHIIJEP_01109 224308.BSU08620 2.07e-236 650.0 COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,4H9PU@91061|Bacilli,1ZBEI@1386|Bacillus 91061|Bacilli S membrane-bound metal-dependent yfhP - - ko:K07038 - - - - ko00000 - - - YdjM HPHIIJEP_01110 224308.BSU08610 0.0 1662.0 COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,4HD9X@91061|Bacilli,1ZCSF@1386|Bacillus 91061|Bacilli S Bacterial membrane protein YfhO yfhO - - - - - - - - - - - YfhO HPHIIJEP_01111 224308.BSU08600 3.43e-236 649.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,1ZD2D@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis csbB - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 HPHIIJEP_01112 224308.BSU08590 1.13e-217 599.0 COG0596@1|root,COG0596@2|Bacteria,1UZ7K@1239|Firmicutes,4HCZB@91061|Bacilli,1ZATX@1386|Bacillus 91061|Bacilli S Alpha beta hydrolase yfhM - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 HPHIIJEP_01113 224308.BSU08580 8.95e-66 201.0 COG5658@1|root,COG5658@2|Bacteria,1UHRY@1239|Firmicutes,4HSIY@91061|Bacilli,1ZK3C@1386|Bacillus 91061|Bacilli S SdpI/YhfL protein family yfhL - - - - - - - - - - - SdpI HPHIIJEP_01114 224308.BSU08570 1.91e-114 328.0 COG3103@1|root,COG3103@2|Bacteria,1UBB8@1239|Firmicutes,4IMQ5@91061|Bacilli,1ZKKP@1386|Bacillus 91061|Bacilli T Bacterial SH3 domain homologues yfhK - - - - - - - - - - - SH3_3 HPHIIJEP_01115 224308.BSU08560 8.95e-60 184.0 2CEK7@1|root,330II@2|Bacteria,1VFTN@1239|Firmicutes,4HNJY@91061|Bacilli,1ZI0N@1386|Bacillus 91061|Bacilli S WVELL protein yfhJ - - - - - - - - - - - WVELL HPHIIJEP_01116 224308.BSU08550 2.25e-27 99.4 2ERTV@1|root,33JD2@2|Bacteria,1VG3A@1239|Firmicutes,4HPKX@91061|Bacilli,1ZIVJ@1386|Bacillus 91061|Bacilli S reproduction sspK - - ko:K06428 - - - - ko00000 - - - SspK HPHIIJEP_01117 224308.BSU08540 9.96e-268 735.0 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli,1ZQ77@1386|Bacillus 91061|Bacilli EGP -transporter yfhI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_01118 224308.BSU08530 4.8e-67 203.0 2C8IW@1|root,32PGC@2|Bacteria,1VADG@1239|Firmicutes,4HNM3@91061|Bacilli,1ZH1I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1811) yfhH - - - - - - - - - - - DUF1811 HPHIIJEP_01119 224308.BSU08520 3.25e-181 505.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,1ZC8N@1386|Bacillus 91061|Bacilli S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX HPHIIJEP_01120 224308.BSU08510 1.8e-218 602.0 COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,4HBRT@91061|Bacilli,1ZBKW@1386|Bacillus 91061|Bacilli S nucleoside-diphosphate sugar epimerase yfhF - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase HPHIIJEP_01122 224308.BSU08490 8.86e-35 119.0 2DJQF@1|root,306WX@2|Bacteria,1U0IF@1239|Firmicutes,4I9X1@91061|Bacilli,1ZJCB@1386|Bacillus 91061|Bacilli S YfhD-like protein yfhD - - - - - - - - - - - YfhD HPHIIJEP_01123 224308.BSU08480 1.66e-137 389.0 COG0778@1|root,COG0778@2|Bacteria,1UYXM@1239|Firmicutes,4HD96@91061|Bacilli,1ZGXE@1386|Bacillus 91061|Bacilli C nitroreductase yfhC - - - - - - - - - - - Nitroreductase HPHIIJEP_01124 224308.BSU08470 2.09e-212 586.0 COG0384@1|root,COG0384@2|Bacteria,1TRAF@1239|Firmicutes,4HAC5@91061|Bacilli,1ZD49@1386|Bacillus 91061|Bacilli S PhzF family yfhB - - - - - - - - - - - PhzC-PhzF HPHIIJEP_01125 224308.BSU08460 4.25e-228 630.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfhA - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU07500 FecCD HPHIIJEP_01126 224308.BSU08450 8.91e-225 621.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HAW8@91061|Bacilli,1ZQ8X@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yfiZ - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU08450 FecCD HPHIIJEP_01127 224308.BSU08440 3.83e-231 636.0 COG0614@1|root,COG0614@2|Bacteria,1TR63@1239|Firmicutes,4HB8N@91061|Bacilli,1ZCYN@1386|Bacillus 91061|Bacilli P ABC transporter substrate-binding protein yfiY GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 HPHIIJEP_01128 224308.BSU08425 0.0 1623.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,1ZCB5@1386|Bacillus 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM HPHIIJEP_01129 224308.BSU08410 2.11e-103 300.0 COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HYD5@91061|Bacilli,1ZD03@1386|Bacillus 91061|Bacilli K transcriptional yfiV GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_01130 224308.BSU08400 0.0 983.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily yfiU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_01131 224308.BSU08390 3.42e-129 366.0 COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,1ZG53@1386|Bacillus 91061|Bacilli S Belongs to the metal hydrolase YfiT family yfiT - - - - - - - - - - - DinB_2 HPHIIJEP_01132 224308.BSU08360 2.68e-252 693.0 COG3936@1|root,COG3936@2|Bacteria,1V5V5@1239|Firmicutes,4HGCW@91061|Bacilli,1ZFFK@1386|Bacillus 91061|Bacilli G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation yfiQ - - ko:K21462 - - - - ko00000 - - - Acyl_transf_3 HPHIIJEP_01133 224308.BSU08350 1.98e-121 349.0 COG1075@1|root,COG1075@2|Bacteria,1VVU8@1239|Firmicutes,4HWN0@91061|Bacilli,1ZB57@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold lip GO:0003674,GO:0003824,GO:0004806,GO:0005575,GO:0005576,GO:0016298,GO:0016787,GO:0016788,GO:0052689 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Lipase_2 HPHIIJEP_01134 224308.BSU08340 1.89e-128 365.0 COG1695@1|root,COG1695@2|Bacteria,1V6TJ@1239|Firmicutes,4HKXY@91061|Bacilli,1ZGRY@1386|Bacillus 91061|Bacilli K transcriptional padR - - - - - - - - - - - PadR,Vir_act_alpha_C HPHIIJEP_01135 224308.BSU08330 1.46e-263 723.0 COG0842@1|root,COG0842@2|Bacteria,1V7HN@1239|Firmicutes,4HGE5@91061|Bacilli,1ZCVY@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 HPHIIJEP_01136 224308.BSU08320 8.25e-271 743.0 COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1V8HM@1239|Firmicutes,4IPM5@91061|Bacilli,1ZRCG@1386|Bacillus 91061|Bacilli V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 HPHIIJEP_01137 224308.BSU08310 2.17e-214 593.0 COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HDH1@91061|Bacilli,1ZPYP@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein drrA - - ko:K01990,ko:K09695 ko02010,map02010 M00252,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.102 - - ABC_tran HPHIIJEP_01138 224308.BSU08300 8.27e-144 407.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,1ZC3A@1386|Bacillus 91061|Bacilli KT LuxR family transcriptional regulator yfiK - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg HPHIIJEP_01139 224308.BSU08290 1.69e-239 663.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HHFU@91061|Bacilli,1ZPX5@1386|Bacillus 91061|Bacilli T Histidine kinase baeS - - - - - - - - - - - HATPase_c,HisKA_3 HPHIIJEP_01140 224308.BSU08240 4.92e-207 572.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,1ZAQI@1386|Bacillus 91061|Bacilli S glyoxalase yfiE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase HPHIIJEP_01141 224308.BSU08230 4.06e-84 249.0 COG2259@1|root,COG2259@2|Bacteria,1VCS2@1239|Firmicutes,4HKRK@91061|Bacilli,1ZHVA@1386|Bacillus 91061|Bacilli S DoxX yfiD3 - - - - - - - - - - - DoxX HPHIIJEP_01142 224308.BSU08220 0.0 1129.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBIW@1386|Bacillus 91061|Bacilli V COG1132 ABC-type multidrug transport system, ATPase and permease components yfiC3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_01143 224308.BSU08210 0.0 1051.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus 91061|Bacilli V ABC transporter yfiB3 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_01144 326423.RBAM_008390 0.0 1407.0 COG5434@1|root,COG5434@2|Bacteria,1TSDM@1239|Firmicutes,4HF01@91061|Bacilli 91061|Bacilli M COG5434 Endopolygalacturonase yobO - - - - - - - - - - - Pectate_lyase_3,Peptidase_G2 HPHIIJEP_01145 224308.BSU08200 0.0 1019.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus 91061|Bacilli G phosphotransferase system glvC - 2.7.1.208 ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 M00268 R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8 - - PTS_EIIB,PTS_EIIC HPHIIJEP_01146 224308.BSU08190 5.03e-180 501.0 COG1737@1|root,COG1737@2|Bacteria,1V1PK@1239|Firmicutes,4HNF6@91061|Bacilli,1ZHAE@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain, rpiR family - GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K03481 - - - - ko00000,ko03000 - - - HTH_6,SIS HPHIIJEP_01147 224308.BSU08180 0.0 900.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,1ZQT2@1386|Bacillus 91061|Bacilli G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases malH - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C HPHIIJEP_01148 224308.BSU08170 5.59e-61 188.0 COG4842@1|root,COG4842@2|Bacteria,1UAGF@1239|Firmicutes,4IKUW@91061|Bacilli,1ZHQG@1386|Bacillus 91061|Bacilli S Belongs to the WXG100 family yfjA - - - - - - - - - - - WXG100 HPHIIJEP_01149 224308.BSU08160 1.94e-270 743.0 2B6C6@1|root,31Z9T@2|Bacteria,1U9MI@1239|Firmicutes,4IJSZ@91061|Bacilli,1ZE74@1386|Bacillus 91061|Bacilli - - yfjB - - - - - - - - - - - - HPHIIJEP_01150 224308.BSU08150 2.5e-185 514.0 295F9@1|root,2ZST0@2|Bacteria,1W1TU@1239|Firmicutes,4I211@91061|Bacilli,1ZEWR@1386|Bacillus 91061|Bacilli - - yfjC - - - - - - - - - - - - HPHIIJEP_01151 224308.BSU08140 6.08e-131 371.0 2BHJ4@1|root,31I9E@2|Bacteria,1UAQF@1239|Firmicutes,4IM33@91061|Bacilli,1ZIZ0@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5381) yfjD - - - - - - - - - - - DUF5381 HPHIIJEP_01152 224308.BSU08130 1.03e-102 298.0 2BHJ4@1|root,32BMJ@2|Bacteria,1TXVF@1239|Firmicutes,4I6XX@91061|Bacilli,1ZF7I@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5381) - - - - - - - - - - - - DUF5381 HPHIIJEP_01153 224308.BSU08120 7.42e-75 223.0 COG1742@1|root,COG1742@2|Bacteria,1V6YJ@1239|Firmicutes,4HIIY@91061|Bacilli,1ZHH6@1386|Bacillus 91061|Bacilli S UPF0060 membrane protein yfjF - - ko:K09771 - - - - ko00000,ko02000 2.A.7.26 - - UPF0060 HPHIIJEP_01154 224308.BSU08110 8.16e-36 121.0 2EH2H@1|root,33AUF@2|Bacteria,1VKXK@1239|Firmicutes,4HRIP@91061|Bacilli,1ZKGU@1386|Bacillus 91061|Bacilli S Belongs to the SspH family sspH - - ko:K06425 - - - - ko00000 - - - SspH HPHIIJEP_01155 224308.BSU08100 0.0 1178.0 COG3284@1|root,COG3284@2|Bacteria,1VHQN@1239|Firmicutes,4HUF7@91061|Bacilli,1ZS1R@1386|Bacillus 91061|Bacilli KQ COG3284 Transcriptional activator of acetoin glycerol metabolism acoR - - ko:K21405 - - - - ko00000,ko03000 - - - GAF,HTH_8,Sigma54_activat HPHIIJEP_01156 224308.BSU08090 0.0 869.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZCM1@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes acoL - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim HPHIIJEP_01157 224308.BSU08080 4.01e-263 723.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,1ZB6D@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding HPHIIJEP_01158 224308.BSU08070 1.59e-243 669.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1ZE4V@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit acoB - - ko:K21417 - - - - ko00000,ko01000 - - - Transket_pyr,Transketolase_C HPHIIJEP_01159 224308.BSU08060 3.21e-243 667.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli,1ZAY4@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit acoA - - ko:K21416 - - - - ko00000,ko01000 - - - E1_dh HPHIIJEP_01161 224308.BSU08040 2.53e-106 306.0 COG4637@1|root,COG4637@2|Bacteria,1VB13@1239|Firmicutes,4HMQY@91061|Bacilli,1ZHPM@1386|Bacillus 91061|Bacilli S Psort location Cytoplasmic, score yfjM - - - - - - - - - - - - HPHIIJEP_01162 224308.BSU08030 1.65e-241 662.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZBSF@1386|Bacillus 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines yfjN - - - - - - - - - - - Dus HPHIIJEP_01163 326423.RBAM_008270 1.92e-56 176.0 2CV5Q@1|root,32SWW@2|Bacteria,1VCMQ@1239|Firmicutes,4HNDT@91061|Bacilli,1ZK4J@1386|Bacillus 91061|Bacilli S YfzA-like protein - - - - - - - - - - - - YfzA HPHIIJEP_01164 224308.BSU08020 0.0 927.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZD4Q@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr HPHIIJEP_01165 224308.BSU08010 5.57e-214 590.0 COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,1ZCV5@1386|Bacillus 91061|Bacilli L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase yfjP GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD HPHIIJEP_01166 224308.BSU08000 7.8e-237 650.0 COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,4HAPC@91061|Bacilli,1ZBVW@1386|Bacillus 91061|Bacilli P Mediates influx of magnesium ions corA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - iYO844.BSU08000 CorA HPHIIJEP_01167 224308.BSU07990 4.43e-190 529.0 COG2084@1|root,COG2084@2|Bacteria,1VS8P@1239|Firmicutes,4HTTT@91061|Bacilli,1ZFJJ@1386|Bacillus 91061|Bacilli I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase yfjR - - - - - - - - - - - NAD_binding_11,NAD_binding_2 HPHIIJEP_01168 224308.BSU07980 2.95e-197 545.0 COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,4HAQI@91061|Bacilli,1ZBYP@1386|Bacillus 91061|Bacilli G deacetylase pdaA GO:0005575,GO:0016020 - ko:K01567 - - - - ko00000,ko01000 - - - Polysacc_deac_1 HPHIIJEP_01169 224308.BSU07970 3.26e-36 122.0 2CEJ8@1|root,33H3W@2|Bacteria,1VMMF@1239|Firmicutes,4HRK8@91061|Bacilli,1ZIWC@1386|Bacillus 91061|Bacilli - - yfjT - - - - - - - - - - - - HPHIIJEP_01170 224308.BSU07955 1.76e-283 773.0 COG0535@1|root,COG0535@2|Bacteria,1TRC8@1239|Firmicutes,4HA9Q@91061|Bacilli,1ZAVK@1386|Bacillus 91061|Bacilli S YfkB-like domain yfkA - - - - - - - - - - - Fer4_12,Fer4_14,Radical_SAM,YfkB HPHIIJEP_01171 224308.BSU07940 4.44e-191 531.0 COG0668@1|root,COG0668@2|Bacteria,1V16H@1239|Firmicutes,4HAP1@91061|Bacilli,1ZEMM@1386|Bacillus 91061|Bacilli M Mechanosensitive ion channel yfkC GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - - - - - - - - - - MS_channel HPHIIJEP_01172 224308.BSU07930 3.69e-189 525.0 28IN6@1|root,2Z8NK@2|Bacteria,1TR7N@1239|Firmicutes,4HBDQ@91061|Bacilli,1ZBTH@1386|Bacillus 91061|Bacilli S YfkD-like protein yfkD - - - - - - - - - - - YfkD HPHIIJEP_01173 224308.BSU07920 1.34e-235 650.0 COG0387@1|root,COG0387@2|Bacteria,1TQN2@1239|Firmicutes,4HB3X@91061|Bacilli,1ZC9V@1386|Bacillus 91061|Bacilli P COG0387 Ca2 H antiporter cax GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex HPHIIJEP_01174 224308.BSU07910 1.9e-278 761.0 COG0477@1|root,COG0477@2|Bacteria,1UIJV@1239|Firmicutes,4ISKN@91061|Bacilli,1ZS6S@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yfkF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like HPHIIJEP_01175 935837.JAEK01000038_gene2870 1.64e-12 60.8 29S58@1|root,30D9S@2|Bacteria,1UB1M@1239|Firmicutes,4IMEH@91061|Bacilli,1ZJYU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01176 224308.BSU07900 9.64e-184 512.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus 91061|Bacilli S Belongs to the UPF0761 family yihY - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB HPHIIJEP_01177 224308.BSU07890 1.03e-66 202.0 COG4980@1|root,COG4980@2|Bacteria,1VGY5@1239|Firmicutes,4HPNI@91061|Bacilli,1ZIVN@1386|Bacillus 91061|Bacilli S gas vesicle protein yfkI - - - - - - - - - - - - HPHIIJEP_01178 224308.BSU07880 9.78e-107 308.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,1ZG7W@1386|Bacillus 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family yfkJ - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc HPHIIJEP_01179 224308.BSU07870 7.27e-42 137.0 COG4840@1|root,COG4840@2|Bacteria,1VEYR@1239|Firmicutes,4HNKK@91061|Bacilli,1ZJ0U@1386|Bacillus 91061|Bacilli S Belongs to the UPF0435 family yfkK - - - - - - - - - - - DUF1128 HPHIIJEP_01180 224308.BSU07860 5.1e-265 728.0 COG0477@1|root,COG2814@2|Bacteria,1VNR0@1239|Firmicutes,4ISCF@91061|Bacilli,1ZCMD@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ydiN3 - - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_01181 224308.BSU07850 1.11e-113 327.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,1ZFMH@1386|Bacillus 91061|Bacilli S protease yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI HPHIIJEP_01182 224308.BSU07840 0.0 2764.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,1ZAY0@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yfkN - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - iYO844.BSU07840 5_nucleotid_C,CBM_5_12,Metallophos,SLH HPHIIJEP_01183 224308.BSU07830 6.16e-160 447.0 COG0778@1|root,COG0778@2|Bacteria,1V1PI@1239|Firmicutes,4HB7V@91061|Bacilli,1ZBI6@1386|Bacillus 91061|Bacilli C nitroreductase frp - - - - - - - - - - iYO844.BSU07830 Nitroreductase HPHIIJEP_01184 224308.BSU07820 1.24e-172 481.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,1ZATF@1386|Bacillus 91061|Bacilli K transcriptional treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_01185 224308.BSU07810 0.0 1182.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C HPHIIJEP_01186 224308.BSU07800 0.0 891.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system treP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 2.7.1.201 ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - iYO844.BSU07800 PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_01187 224308.BSU07790 0.0 982.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein yfkQ - - ko:K06295,ko:K06307 - - - - ko00000 - - - GerA HPHIIJEP_01188 224308.BSU07780 1.08e-269 739.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZDF7@1386|Bacillus 91061|Bacilli S spore germination yfkR - - ko:K06297,ko:K06308 - - - - ko00000 - - - Spore_GerAC HPHIIJEP_01190 224308.BSU07760 2.1e-247 680.0 COG0531@1|root,COG0531@2|Bacteria,1TSIB@1239|Firmicutes,4ISWV@91061|Bacilli,1ZEKN@1386|Bacillus 91061|Bacilli E Spore germination protein yfkT - - ko:K06309 - - - - ko00000 - - - Spore_permease HPHIIJEP_01191 224308.BSU07750 0.0 874.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter yflA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp HPHIIJEP_01192 224308.BSU07735 1.89e-87 257.0 2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,4HKCW@91061|Bacilli,1ZI9Y@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1992) ydhN1 - - - - - - - - - - - DUF1992 HPHIIJEP_01193 224308.BSU07710 0.0 1275.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yflE GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase HPHIIJEP_01194 224308.BSU07700 0.0 871.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZAZ3@1386|Bacillus 91061|Bacilli G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific nagE - 2.7.1.193,2.7.1.199 ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00267,M00809 R02738,R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_01195 224308.BSU07690 1.14e-178 497.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZCVZ@1386|Bacillus 91061|Bacilli E Methionine aminopeptidase yflG - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 HPHIIJEP_01196 224308.BSU07680 3.63e-66 201.0 2DB6C@1|root,32TWU@2|Bacteria,1VC4Z@1239|Firmicutes,4HKEX@91061|Bacilli,1ZGUZ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3243) yflH - - - - - - - - - - - DUF3243 HPHIIJEP_01197 224308.BSU07670 6.9e-27 98.2 29SE6@1|root,30DIX@2|Bacteria,1UBC7@1239|Firmicutes,4IMR3@91061|Bacilli,1ZKN8@1386|Bacillus 91061|Bacilli - - yflI - - - - - - - - - - - - HPHIIJEP_01198 224308.BSU07660 3.16e-25 93.6 2EG6C@1|root,339Y6@2|Bacteria,1VPY7@1239|Firmicutes,4HRNE@91061|Bacilli,1ZK0I@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2639) yflJ - - - - - - - - - - - DUF2639 HPHIIJEP_01199 224308.BSU07650 3.42e-157 441.0 COG2258@1|root,COG2258@2|Bacteria,1UB2C@1239|Firmicutes,4HB26@91061|Bacilli,1ZCRA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yflK - - - - - - - - - - - 3-alpha,MOSC HPHIIJEP_01200 224308.BSU07640 2.97e-59 182.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,1ZITT@1386|Bacillus 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase HPHIIJEP_01201 224308.BSU07630 1.95e-275 751.0 COG4362@1|root,COG4362@2|Bacteria,1TRDM@1239|Firmicutes,4HAR0@91061|Bacilli,1ZB33@1386|Bacillus 91061|Bacilli C Belongs to the NOS family. Bacterial NOS oxygenase subfamily nos GO:0001505,GO:0003674,GO:0003824,GO:0004497,GO:0004517,GO:0006807,GO:0006809,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017144,GO:0034641,GO:0042133,GO:0042136,GO:0044237,GO:0044249,GO:0044271,GO:0046209,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:1903409,GO:2001057 1.14.14.47 ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 - R11711,R11712,R11713 RC00177,RC00330,RC01044 ko00000,ko00001,ko01000 - - - NO_synthase HPHIIJEP_01202 224308.BSU07620 1.7e-192 533.0 COG0491@1|root,COG0491@2|Bacteria,1TQGU@1239|Firmicutes,4HBJ3@91061|Bacilli,1ZB0U@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yflN - - - - - - - - - - - Lactamase_B HPHIIJEP_01203 224308.BSU07610 5.35e-288 789.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,1ZFH7@1386|Bacillus 91061|Bacilli C Citrate transporter citM GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K03300,ko:K11639 ko02020,map02020 - - - ko00000,ko00001 2.A.11,2.A.11.1.1 - - CitMHS HPHIIJEP_01204 224308.BSU07600 3.98e-230 633.0 COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,4HBWA@91061|Bacilli,1ZB42@1386|Bacillus 91061|Bacilli S Tripartite tricarboxylate transporter family receptor yflP - - - - - - - - - - - TctC HPHIIJEP_01205 224308.BSU07590 2.68e-152 429.0 COG4565@1|root,COG4565@2|Bacteria,1V1D7@1239|Firmicutes,4HFWB@91061|Bacilli,1ZFEC@1386|Bacillus 91061|Bacilli T response regulator citT - - ko:K11638 ko02020,map02020 M00487 - - ko00000,ko00001,ko00002,ko02022 - - - CitT,HTH_11,Response_reg HPHIIJEP_01206 224308.BSU07580 0.0 1021.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism citS - 2.7.13.3 ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 M00487,M00489,M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,PAS_9,SPOB_a,sCache_3_2 HPHIIJEP_01207 224308.BSU07570 0.0 877.0 COG0471@1|root,COG0471@2|Bacteria,1TSGE@1239|Firmicutes,4HDE4@91061|Bacilli,1ZC2I@1386|Bacillus 91061|Bacilli P Sodium:sulfate symporter transmembrane region yflS - - ko:K03319 - - - - ko00000 2.A.47 - - Na_sulph_symp HPHIIJEP_01208 224308.BSU07560 3.48e-307 837.0 COG3866@1|root,COG3866@2|Bacteria,1U9EG@1239|Firmicutes,4HEBZ@91061|Bacilli,1ZE00@1386|Bacillus 91061|Bacilli G Pectate lyase pel - 4.2.2.2 ko:K01728 ko00040,ko02024,map00040,map02024 - R02361,R06240 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pec_lyase_C HPHIIJEP_01209 224308.BSU07550 1.71e-76 228.0 2DJ0G@1|root,32UC2@2|Bacteria,1VCTC@1239|Firmicutes,4HKM5@91061|Bacilli,1ZHWS@1386|Bacillus 91061|Bacilli S Heat induced stress protein YflT yflT - - - - - - - - - - - YflT HPHIIJEP_01210 1274524.BSONL12_06998 1.06e-31 116.0 29RI0@1|root,30CKZ@2|Bacteria,1UA2M@1239|Firmicutes,4IKC0@91061|Bacilli,1ZGDW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3212) - - - - - - - - - - - - DUF3212 HPHIIJEP_01211 224308.BSU07520 2.76e-219 605.0 COG4594@1|root,COG4594@2|Bacteria,1U1RC@1239|Firmicutes,4HEP3@91061|Bacilli,1ZEMX@1386|Bacillus 91061|Bacilli P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component yfmC GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU07520 Peripla_BP_2 HPHIIJEP_01212 224308.BSU07510 8.17e-221 611.0 COG0609@1|root,COG0609@2|Bacteria,1UC21@1239|Firmicutes,4HDZP@91061|Bacilli,1ZF51@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_01213 224308.BSU07500 2.01e-221 612.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZD7X@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fecD - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU07500 FecCD HPHIIJEP_01214 224308.BSU07490 1.4e-192 534.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZEBC@1386|Bacillus 91061|Bacilli P ATPases associated with a variety of cellular activities fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran HPHIIJEP_01215 224308.BSU07450 6.69e-239 657.0 COG2130@1|root,COG2130@2|Bacteria,1TQUE@1239|Firmicutes,4HCHY@91061|Bacilli,1ZC4N@1386|Bacillus 91061|Bacilli S N-terminal domain of oxidoreductase yfmJ - - ko:K07119 - - - - ko00000 - - - ADH_N_2,ADH_zinc_N HPHIIJEP_01216 1051501.AYTL01000011_gene152 3.75e-98 285.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yfmK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_3 HPHIIJEP_01217 224308.BSU07430 7.25e-264 723.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,1ZC9I@1386|Bacillus 91061|Bacilli L COG0513 Superfamily II DNA and RNA helicases yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C HPHIIJEP_01218 1051501.AYTL01000011_gene150 0.0 1009.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,1ZB1Y@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn HPHIIJEP_01219 1051501.AYTL01000011_gene149 3.95e-74 224.0 2F25R@1|root,33V44@2|Bacteria,1VVA1@1239|Firmicutes,4HVY4@91061|Bacilli,1ZHAM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01221 1292035.H476_0316 9.1e-23 102.0 2ESZK@1|root,33KHU@2|Bacteria,1VP9E@1239|Firmicutes,24VGN@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - HPHIIJEP_01222 1274524.BSONL12_23140 4.96e-64 210.0 COG1404@1|root,COG1404@2|Bacteria,1UV6S@1239|Firmicutes,4HV9I@91061|Bacilli,1ZH16@1386|Bacillus 91061|Bacilli O Subtilase family - - - - - - - - - - - - Peptidase_S8 HPHIIJEP_01223 224308.BSU07400 2.42e-263 724.0 COG0477@1|root,COG2814@2|Bacteria,1TRRB@1239|Firmicutes,4HAUF@91061|Bacilli,1ZDMB@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yfmO - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1 HPHIIJEP_01224 224308.BSU07390 3.54e-90 265.0 COG0789@1|root,COG0789@2|Bacteria,1VBDA@1239|Firmicutes,4HMS4@91061|Bacilli,1ZIAJ@1386|Bacillus 91061|Bacilli K transcriptional yfmP - - ko:K21902 - - - - ko00000,ko03000 - - - MerR_1 HPHIIJEP_01225 224308.BSU07380 3.61e-96 280.0 2BT7F@1|root,32NCS@2|Bacteria,1V7YX@1239|Firmicutes,4HJIR@91061|Bacilli,1ZH1S@1386|Bacillus 91061|Bacilli S Uncharacterised protein from bacillus cereus group yfmQ - - - - - - - - - - - YfmQ HPHIIJEP_01226 224308.BSU07370 0.0 1203.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,1ZBTF@1386|Bacillus 91061|Bacilli S COG0488 ATPase components of ABC transporters with duplicated ATPase domains yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn HPHIIJEP_01227 224308.BSU07360 5.14e-161 456.0 COG0840@1|root,COG0840@2|Bacteria,1V8NI@1239|Firmicutes,4HAGI@91061|Bacilli,1ZDCZ@1386|Bacillus 91061|Bacilli NT chemotaxis protein yfmS - - - - - - - - - - - MCPsignal HPHIIJEP_01228 224308.BSU07350 0.0 966.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively yfmT GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0018479,GO:0055114 1.2.1.3,1.2.1.67 ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05699,R06366,R08146 RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38830 Aldedh HPHIIJEP_01229 224308.BSU07340 2.4e-312 853.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,1ZBB0@1386|Bacillus 91061|Bacilli E amino acid yfnA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 HPHIIJEP_01230 224308.BSU07330 2.49e-166 465.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli,1ZE98@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 HPHIIJEP_01231 224308.BSU07320 2.94e-266 732.0 COG2223@1|root,COG2223@2|Bacteria,1TPTN@1239|Firmicutes,4HA7C@91061|Bacilli,1ZB21@1386|Bacillus 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily fsr GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 HPHIIJEP_01232 224308.BSU07310 3.88e-242 663.0 COG1442@1|root,COG1442@2|Bacteria,1UZ8Q@1239|Firmicutes,4HURC@91061|Bacilli,1ZF68@1386|Bacillus 91061|Bacilli M Nucleotide-diphospho-sugar transferase yfnD - - - - - - - - - - - Nucleotid_trans HPHIIJEP_01233 224308.BSU07300 2.84e-285 779.0 COG1216@1|root,COG1216@2|Bacteria,1VDP9@1239|Firmicutes,4IPY5@91061|Bacilli,1ZREN@1386|Bacillus 91061|Bacilli S Glycosyltransferase like family 2 yfnE - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_01234 224308.BSU07290 9.02e-228 626.0 COG1442@1|root,COG1442@2|Bacteria,1VS6N@1239|Firmicutes,4HUAY@91061|Bacilli,1ZRVS@1386|Bacillus 91061|Bacilli M Nucleotide-diphospho-sugar transferase yfnF - - - - - - - - - - - Nucleotid_trans HPHIIJEP_01235 224308.BSU07280 1.37e-219 606.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4ISWU@91061|Bacilli,1ZFBK@1386|Bacillus 91061|Bacilli M dehydratase yfnG - 4.2.1.45,4.2.1.46 ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 M00793 R02426,R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd HPHIIJEP_01236 224308.BSU07270 4.01e-186 516.0 COG1208@1|root,COG1208@2|Bacteria,1TT1F@1239|Firmicutes,4HUVJ@91061|Bacilli,1ZQJC@1386|Bacillus 91061|Bacilli JM Nucleotidyl transferase yfnH - 2.7.7.33 ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R00956 RC00002 ko00000,ko00001,ko01000 - - - NTP_transferase HPHIIJEP_01237 224308.BSU07260 0.0 1267.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase HPHIIJEP_01238 224308.BSU07250 0.0 2093.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1TS1E@1239|Firmicutes,4HCWS@91061|Bacilli,1ZQAP@1386|Bacillus 91061|Bacilli C Belongs to the cytochrome P450 family cypD GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0004497,GO:0005488,GO:0005504,GO:0005506,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0016705,GO:0016712,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031406,GO:0032553,GO:0032787,GO:0033293,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 HPHIIJEP_01239 224308.BSU07240 3.53e-254 697.0 2CEJD@1|root,2Z81V@2|Bacteria,1UD9R@1239|Firmicutes,4HAPP@91061|Bacilli,1ZC32@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3900) yetN - - - - - - - - - - - DUF3898,DUF3900 HPHIIJEP_01240 224308.BSU07230 5.96e-264 723.0 COG0654@1|root,COG0654@2|Bacteria,1VUA1@1239|Firmicutes,4HTBK@91061|Bacilli,1ZE9G@1386|Bacillus 91061|Bacilli CH FAD binding domain yetM - - - - - - - - - - - FAD_binding_3 HPHIIJEP_01241 224308.BSU07220 1.86e-114 328.0 COG1846@1|root,COG1846@2|Bacteria,1VIXS@1239|Firmicutes,4HPYM@91061|Bacilli,1ZJKZ@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein yetL GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_01242 224308.BSU07210 2.45e-201 560.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HCSH@91061|Bacilli,1ZCZY@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA HPHIIJEP_01243 224308.BSU07200 2.55e-135 385.0 COG0670@1|root,COG0670@2|Bacteria,1V6RG@1239|Firmicutes,4HISH@91061|Bacilli,1ZCV6@1386|Bacillus 91061|Bacilli S Belongs to the BI1 family yetJ - - ko:K06890 - - - - ko00000 - - - Bax1-I HPHIIJEP_01244 224308.BSU07190 3.81e-28 101.0 COG5583@1|root,COG5583@2|Bacteria 2|Bacteria S Uncharacterized small protein (DUF2292) yezD - - - - - - - - - - - DUF2292 HPHIIJEP_01245 1051501.AYTL01000011_gene124 4.37e-185 517.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS HPHIIJEP_01246 1051501.AYTL01000011_gene123 1.75e-44 152.0 2C860@1|root,32RKH@2|Bacteria,1VATE@1239|Firmicutes,4HMZP@91061|Bacilli,1ZHVD@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01247 224308.BSU07160 2.47e-85 251.0 COG0346@1|root,COG0346@2|Bacteria,1V4S3@1239|Firmicutes,4HIIR@91061|Bacilli,1ZGP1@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yetH - - - - - - - - - - - Glyoxalase HPHIIJEP_01248 224308.BSU07150 1.9e-72 217.0 COG2329@1|root,COG2329@2|Bacteria,1VBS6@1239|Firmicutes,4HKUG@91061|Bacilli,1ZHZ4@1386|Bacillus 91061|Bacilli S Antibiotic biosynthesis monooxygenase yetG - 1.14.99.48 ko:K07145 ko00860,ko01110,map00860,map01110 - R10468,R10510 RC03185 ko00000,ko00001,ko01000 - - - ABM HPHIIJEP_01249 224308.BSU07140 3.66e-157 441.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HFCN@91061|Bacilli,1ZFK2@1386|Bacillus 91061|Bacilli S membrane yetF - - - - - - - - - - - DUF421 HPHIIJEP_01250 224308.BSU07130 0.0 880.0 COG1486@1|root,COG1486@2|Bacteria,1TREJ@1239|Firmicutes,4HUZQ@91061|Bacilli,1ZEWX@1386|Bacillus 91061|Bacilli G Family 4 glycosyl hydrolase - - 3.2.1.22 ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_4,Glyco_hydro_4C HPHIIJEP_01251 224308.BSU07120 7.85e-209 577.0 COG0395@1|root,COG0395@2|Bacteria,1TS0D@1239|Firmicutes,4HA5Y@91061|Bacilli,1ZQ4V@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K17320 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 HPHIIJEP_01252 224308.BSU07110 2.78e-225 621.0 COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,4HATZ@91061|Bacilli,1ZAQ3@1386|Bacillus 91061|Bacilli G COG4209 ABC-type polysaccharide transport system, permease component lplB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 HPHIIJEP_01253 224308.BSU07100 0.0 996.0 COG1653@1|root,COG1653@2|Bacteria,1TRD0@1239|Firmicutes,4HA0M@91061|Bacilli,1ZE2D@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein lplA - - ko:K17318 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - SBP_bac_1 HPHIIJEP_01254 224308.BSU07090 0.0 1778.0 28I2Y@1|root,2Z86X@2|Bacteria,1UYYK@1239|Firmicutes,4HEZF@91061|Bacilli,1ZES9@1386|Bacillus 91061|Bacilli - - yetA - - - - - - - - - - - - HPHIIJEP_01255 224308.BSU07080 0.0 1369.0 COG1874@1|root,COG1874@2|Bacteria,1VRKP@1239|Firmicutes,4HUMJ@91061|Bacilli,1ZFF3@1386|Bacillus 91061|Bacilli G beta-galactosidase activity - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M,Lipase_GDSL_2 HPHIIJEP_01256 224308.BSU07070 9.13e-160 447.0 COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,4IPY4@91061|Bacilli,1ZQND@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_01257 224308.BSU07060 0.0 1243.0 COG3401@1|root,COG3401@2|Bacteria,1TQR3@1239|Firmicutes,4HBSX@91061|Bacilli,1ZEBX@1386|Bacillus 91061|Bacilli E cell wall organization yesX - 4.2.2.23,4.2.2.24 ko:K18197,ko:K18198 - - - - ko00000,ko01000 - PL11 - FG-GAP,Lipase_GDSL_2,fn3 HPHIIJEP_01258 224308.BSU07050 0.0 1245.0 COG3401@1|root,COG3401@2|Bacteria,1TQR3@1239|Firmicutes,4HBSX@91061|Bacilli,1ZEBX@1386|Bacillus 91061|Bacilli E cell wall organization - - 4.2.2.23,4.2.2.24 ko:K18197,ko:K18198 - - - - ko00000,ko01000 - PL11 - FG-GAP,Lipase_GDSL_2,fn3 HPHIIJEP_01259 224308.BSU07040 5.71e-145 409.0 COG5578@1|root,COG5578@2|Bacteria,1V69Y@1239|Firmicutes,4I499@91061|Bacilli,1ZFT5@1386|Bacillus 91061|Bacilli S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 HPHIIJEP_01260 224308.BSU07030 5.08e-163 455.0 29765@1|root,2ZUE2@2|Bacteria,1V4EN@1239|Firmicutes,4HH0R@91061|Bacilli,1ZDUY@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1961) yesU - - - - - - - - - - - DUF1961 HPHIIJEP_01261 224308.BSU07020 1.63e-167 468.0 COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,4HHCC@91061|Bacilli,1ZEN8@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_01262 224308.BSU07010 0.0 1442.0 COG2207@1|root,COG2207@2|Bacteria,1TTA3@1239|Firmicutes,4HEIT@91061|Bacilli,1ZD14@1386|Bacillus 91061|Bacilli K Transcriptional regulator yesS GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - - - - - - - - - - HTH_18,dCache_1 HPHIIJEP_01263 224308.BSU07000 1.33e-252 692.0 COG4225@1|root,COG4225@2|Bacteria,1UYKV@1239|Firmicutes,4HEBW@91061|Bacilli,1ZDHW@1386|Bacillus 91061|Bacilli S Glycosyl Hydrolase Family 88 - - 3.2.1.172 ko:K15532 - - - - ko00000,ko01000 - GH105 - Glyco_hydro_88 HPHIIJEP_01264 224308.BSU06990 8.48e-209 577.0 COG0395@1|root,COG0395@2|Bacteria,1TSYB@1239|Firmicutes,4HBHQ@91061|Bacilli,1ZEBZ@1386|Bacillus 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - iYO844.BSU06990 BPD_transp_1 HPHIIJEP_01265 224308.BSU06980 5.79e-218 602.0 COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HB63@91061|Bacilli,1ZAQ5@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component yesP GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 HPHIIJEP_01266 224308.BSU06970 1.68e-313 853.0 COG1653@1|root,COG1653@2|Bacteria,1TQJV@1239|Firmicutes,4HBW5@91061|Bacilli,1ZBWM@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein yesO - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - iYO844.BSU06970 SBP_bac_1,SBP_bac_8 HPHIIJEP_01267 224308.BSU06960 1.62e-256 704.0 COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UZKW@1239|Firmicutes,4HF1S@91061|Bacilli,1ZPXG@1386|Bacillus 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - ko:K07720 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_18,Response_reg HPHIIJEP_01268 224308.BSU06950 0.0 1115.0 COG2972@1|root,COG2972@2|Bacteria,1UU89@1239|Firmicutes,4HECK@91061|Bacilli,1ZAUI@1386|Bacillus 91061|Bacilli T Histidine kinase yesM - 2.7.13.3 ko:K07718 ko02020,map02020 M00519 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,His_kinase,dCache_1 HPHIIJEP_01269 224308.BSU06940 1.04e-131 375.0 COG5578@1|root,COG5578@2|Bacteria,1V4YK@1239|Firmicutes,4HHBR@91061|Bacilli,1ZGAP@1386|Bacillus 91061|Bacilli S Protein of unknown function, DUF624 yesL - - - - - - - - - - - DUF624 HPHIIJEP_01271 224308.BSU06920 1.14e-128 365.0 COG0454@1|root,COG0454@2|Bacteria,1VBXZ@1239|Firmicutes,4ISWT@91061|Bacilli,1ZQWG@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yesJ - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_01272 224308.BSU06910 1.04e-133 379.0 COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4HA34@91061|Bacilli,1ZQQY@1386|Bacillus 91061|Bacilli P Spore Coat cotJC - - ko:K06334 - - - - ko00000 - - - Mn_catalase HPHIIJEP_01273 224308.BSU06900 2.31e-61 187.0 2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,4HKID@91061|Bacilli,1ZI8X@1386|Bacillus 91061|Bacilli S CotJB protein cotJB - - ko:K06333 - - - - ko00000 - - - CotJB HPHIIJEP_01274 224308.BSU06890 3.8e-60 184.0 2E85N@1|root,332J6@2|Bacteria,1VFSE@1239|Firmicutes,4HNIY@91061|Bacilli,1ZISW@1386|Bacillus 91061|Bacilli S Spore coat associated protein JA (CotJA) cotJA - - ko:K06332 - - - - ko00000 - - - CotJA HPHIIJEP_01275 224308.BSU06880 4.79e-193 536.0 COG0702@1|root,COG0702@2|Bacteria,1VQTZ@1239|Firmicutes,4HU7Q@91061|Bacilli,1ZGK1@1386|Bacillus 91061|Bacilli GM NAD(P)H-binding yesF - - - - - - - - - - - Epimerase,NAD_binding_10,NmrA HPHIIJEP_01276 224308.BSU06870 1.94e-104 301.0 COG3631@1|root,COG3631@2|Bacteria,1VXIF@1239|Firmicutes,4HXSI@91061|Bacilli,1ZNB7@1386|Bacillus 91061|Bacilli S SnoaL-like domain yesE - - ko:K06893 - - - - ko00000 - - - SnoaL_2 HPHIIJEP_01277 224308.BSU06860 4.04e-129 367.0 COG1309@1|root,COG1309@2|Bacteria,1VTZE@1239|Firmicutes,4HTVN@91061|Bacilli,1ZH8K@1386|Bacillus 91061|Bacilli K Transcriptional regulator dhaR3 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K16137 - - - - ko00000,ko03000 - - - TetR_N HPHIIJEP_01279 224308.BSU06840 6.29e-162 454.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg HPHIIJEP_01281 224308.BSU06830 1.12e-267 733.0 COG0457@1|root,COG0457@2|Bacteria,1TVDD@1239|Firmicutes,4IJYM@91061|Bacilli,1ZEMY@1386|Bacillus 91061|Bacilli S Tetratricopeptide repeat rapH - - ko:K06366 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - TPR_12,TPR_2,TPR_7 HPHIIJEP_01282 1292035.H476_0759 4.24e-14 79.7 COG3755@1|root,COG3755@2|Bacteria,1VGNZ@1239|Firmicutes,24SYM@186801|Clostridia 186801|Clostridia S Pfam:DUF1311 - - - - - - - - - - - - LprI HPHIIJEP_01283 326423.RBAM_029550 5.77e-69 211.0 2C8HY@1|root,2ZE9U@2|Bacteria,1W1MD@1239|Firmicutes,4I0FY@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01284 224308.BSU06820 3.72e-118 345.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - - HPHIIJEP_01285 224308.BSU06820 9.53e-74 230.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - - HPHIIJEP_01286 880070.Cycma_3431 6.96e-127 371.0 COG3586@1|root,COG3586@2|Bacteria,4NERW@976|Bacteroidetes,47VPD@768503|Cytophagia 976|Bacteroidetes L endonuclease activity - - - - - - - - - - - - - HPHIIJEP_01288 1051501.AYTL01000011_gene82 0.0 1207.0 COG5444@1|root,COG5444@2|Bacteria,1V674@1239|Firmicutes,4HKPS@91061|Bacilli,1ZF5M@1386|Bacillus 91061|Bacilli L nucleic acid phosphodiester bond hydrolysis - - - - - - - - - - - - Endonuclea_NS_2,LXG HPHIIJEP_01289 326423.RBAM_007210 1.31e-73 224.0 COG5444@1|root,32YNG@2|Bacteria,1VJMI@1239|Firmicutes,4HPD8@91061|Bacilli,1ZI9K@1386|Bacillus 91061|Bacilli S Protein of unknown function, DUF600 - - - - - - - - - - - - DUF600 HPHIIJEP_01290 224308.BSU06811 1.39e-85 253.0 COG5444@1|root,32YNG@2|Bacteria,1VJMI@1239|Firmicutes,4HPD8@91061|Bacilli,1ZI9K@1386|Bacillus 91061|Bacilli S Protein of unknown function, DUF600 - - - - - - - - - - - - DUF600 HPHIIJEP_01291 1384049.CD29_03860 0.0 1572.0 COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,4ISM0@91061|Bacilli 91061|Bacilli L DEAD DEAH box helicase - - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII HPHIIJEP_01292 1237149.C900_05147 1.17e-59 202.0 COG0732@1|root,COG0732@2|Bacteria,4NQ5R@976|Bacteroidetes 976|Bacteroidetes V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S HPHIIJEP_01293 546275.FUSPEROL_02600 1.29e-39 140.0 COG0732@1|root,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain - - 2.1.1.72,3.1.21.3 ko:K01154,ko:K03427 - - - - ko00000,ko01000,ko02048 - - - Methylase_S HPHIIJEP_01294 1384049.CD29_03850 1.3e-243 682.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,3IYUD@400634|Lysinibacillus 91061|Bacilli V HsdM N-terminal domain - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase HPHIIJEP_01295 702450.CUW_2199 9.03e-21 104.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,3VPGP@526524|Erysipelotrichia 526524|Erysipelotrichia V Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - N6_Mtase HPHIIJEP_01298 720555.BATR1942_00900 0.0 890.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,1ZB9G@1386|Bacillus 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rlmCD GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr HPHIIJEP_01299 224308.BSU06720 1.8e-218 602.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,1ZBPD@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat HPHIIJEP_01300 224308.BSU06710 0.0 1816.0 COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,4HAFP@91061|Bacilli,1ZBJ3@1386|Bacillus 91061|Bacilli V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family swrC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran HPHIIJEP_01301 224308.BSU06700 7.45e-184 513.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,1ZFND@1386|Bacillus 91061|Bacilli K Transcriptional regulator yerO GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_01302 224308.BSU06690 0.0 932.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,1ZB3K@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey HPHIIJEP_01304 1051501.AYTL01000011_gene70 7.37e-61 187.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln HPHIIJEP_01305 224308.BSU06660 0.0 909.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K03307,ko:K11928 - - - - ko00000,ko02000 2.A.21,2.A.21.2 - - SSF HPHIIJEP_01306 224308.BSU06650 2.29e-160 449.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HGHY@91061|Bacilli,1ZBY0@1386|Bacillus 91061|Bacilli S MgtC SapB transporter sapB - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC HPHIIJEP_01307 224308.BSU06640 8.56e-251 687.0 COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,1ZEJM@1386|Bacillus 91061|Bacilli S homoserine kinase type II (protein kinase fold) yerI - - - - - - - - - - - APH HPHIIJEP_01308 224308.BSU06630 1.02e-280 768.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,1ZBGV@1386|Bacillus 91061|Bacilli S COG4851 Protein involved in sex pheromone biosynthesis camS - - - - - - - - - - - CamS HPHIIJEP_01309 224308.BSU06620 0.0 1276.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,1ZATN@1386|Bacillus 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 HPHIIJEP_01310 224308.BSU06610 0.0 1429.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C HPHIIJEP_01311 224308.BSU06600 1.1e-161 452.0 COG1646@1|root,COG1646@2|Bacteria,1TQQK@1239|Firmicutes,4H9YW@91061|Bacilli,1ZBBT@1386|Bacillus 91061|Bacilli I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales pcrB GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K07094 - - - - ko00000,ko01000 - - - PcrB HPHIIJEP_01313 224308.BSU06590 0.0 1048.0 COG0069@1|root,COG0069@2|Bacteria,1TSHA@1239|Firmicutes,4HA97@91061|Bacilli,1ZCQH@1386|Bacillus 91061|Bacilli E Belongs to the glutamate synthase family yerD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 - R00021,R10086 RC00006,RC00010 ko00000,ko00001,ko01000 - - - Glu_synthase HPHIIJEP_01314 1051501.AYTL01000011_gene61 7.62e-68 205.0 COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,4HKS8@91061|Bacilli,1ZH87@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yerC - - - - - - - - - - - Trp_repressor HPHIIJEP_01315 224308.BSU06570 9.58e-244 669.0 COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3048) C-terminal domain yerB - - - - - - - - - - - DUF3048,DUF3048_C HPHIIJEP_01316 224308.BSU06560 0.0 1186.0 COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,4HAIR@91061|Bacilli,1ZAY2@1386|Bacillus 91061|Bacilli F adenine deaminase yerA GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 HPHIIJEP_01317 1051501.AYTL01000011_gene58 3.45e-37 127.0 2EAXM@1|root,334YP@2|Bacteria,1VIHS@1239|Firmicutes,4HR0C@91061|Bacilli,1ZJ0E@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892 HPHIIJEP_01318 224308.BSU06550 1.12e-270 743.0 COG0531@1|root,COG0531@2|Bacteria,1TT8K@1239|Firmicutes,4HCAU@91061|Bacilli,1ZCR4@1386|Bacillus 91061|Bacilli E Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - ko:K16263 - - - - ko00000,ko02000 2.A.3.13 - - AA_permease_2 HPHIIJEP_01319 224308.BSU06530 1.63e-297 812.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,1ZCE3@1386|Bacillus 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05245,iYO844.BSU06530 GARS_A,GARS_C,GARS_N HPHIIJEP_01320 224308.BSU06520 0.0 989.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1ZD5E@1386|Bacillus 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS HPHIIJEP_01321 224308.BSU06510 2.09e-136 386.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,1ZFSE@1386|Bacillus 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N HPHIIJEP_01322 224308.BSU06500 9.88e-240 660.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,1ZBPS@1386|Bacillus 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C HPHIIJEP_01323 224308.BSU06490 0.0 936.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,1ZCE0@1386|Bacillus 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran HPHIIJEP_01324 224308.BSU06480 0.0 1454.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,1ZCN8@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C HPHIIJEP_01325 224308.BSU06470 1.15e-167 468.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,1ZB9C@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 HPHIIJEP_01326 224308.BSU06460 3.79e-52 164.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,1ZHUG@1386|Bacillus 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS HPHIIJEP_01327 224308.BSU06450 8.32e-168 469.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,1ZAWJ@1386|Bacillus 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt HPHIIJEP_01328 224308.BSU06440 8.03e-314 854.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,1ZC7P@1386|Bacillus 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 HPHIIJEP_01329 224308.BSU06430 2.05e-275 753.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,1ZB8P@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp HPHIIJEP_01330 224308.BSU06420 2.28e-108 312.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1ZFRE@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC HPHIIJEP_01331 224308.BSU06410 3.13e-38 127.0 2C5CS@1|root,33A0C@2|Bacteria,1VKIZ@1239|Firmicutes,4HRCC@91061|Bacilli,1ZJ2K@1386|Bacillus 91061|Bacilli S NETI protein yebG - - - - - - - - - - - NETI HPHIIJEP_01332 224308.BSU06400 5.36e-120 343.0 COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,1ZBPZ@1386|Bacillus 91061|Bacilli S UPF0316 protein yebE - - - - - - - - - - - DUF2179 HPHIIJEP_01334 224308.BSU06380 5.85e-165 464.0 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli,1ZF8F@1386|Bacillus 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 HPHIIJEP_01335 224308.BSU06370 2.41e-283 778.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZARH@1386|Bacillus 91061|Bacilli S permease pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - iYO844.BSU06370 Xan_ur_permease HPHIIJEP_01336 720555.BATR1942_00705 0.0 883.0 28PT3@1|root,2ZCEG@2|Bacteria,1V3FJ@1239|Firmicutes,4HG7M@91061|Bacilli,1ZFCJ@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4179) - - - - - - - - - - - - DUF4179 HPHIIJEP_01337 720555.BATR1942_00700 1.73e-108 314.0 COG1595@1|root,COG1595@2|Bacteria,1VYFR@1239|Firmicutes,4HNBH@91061|Bacilli,1ZQI1@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01338 224308.BSU06360 0.0 1041.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,1ZB6Z@1386|Bacillus 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase HPHIIJEP_01339 224308.BSU06350 0.0 1380.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,1ZBUN@1386|Bacillus 91061|Bacilli E COG1305 Transglutaminase-like enzymes yebA - - - - - - - - - - - DUF4129,Transglut_core HPHIIJEP_01340 224308.BSU06340 3.2e-285 779.0 COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,1ZCAS@1386|Bacillus 91061|Bacilli S conserved protein (some members contain a von Willebrand factor type A (vWA) domain) yeaD - - - - - - - - - - - DUF58 HPHIIJEP_01341 224308.BSU06330 7.99e-226 622.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,1ZDJ1@1386|Bacillus 91061|Bacilli S COG0714 MoxR-like ATPases yeaC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 HPHIIJEP_01342 224308.BSU06320 1.76e-198 551.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer HPHIIJEP_01343 224308.BSU06310 0.0 875.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZS14@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases gabP - - ko:K11735 - - - - ko00000,ko02000 2.A.3.1.4,2.A.3.1.5 - iYO844.BSU06310 AA_permease HPHIIJEP_01344 224308.BSU06300 0.0 1072.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,1ZD48@1386|Bacillus 91061|Bacilli Q multicopper oxidases cotA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 ko:K06324 - - - - ko00000,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 HPHIIJEP_01345 224308.BSU06290 7.33e-224 618.0 28IH1@1|root,2Z8IC@2|Bacteria,1TSE5@1239|Firmicutes,4HD81@91061|Bacilli,1ZDYE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4003) yeaA - - - - - - - - - - - DUF4003 HPHIIJEP_01346 224308.BSU06280 3.45e-200 553.0 COG2267@1|root,COG2267@2|Bacteria,1UIX9@1239|Firmicutes,4ISVM@91061|Bacilli,1ZREK@1386|Bacillus 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 HPHIIJEP_01347 224308.BSU06270 8.2e-48 152.0 2CGYI@1|root,32YUY@2|Bacteria,1VGI2@1239|Firmicutes,4HPBN@91061|Bacilli,1ZK65@1386|Bacillus 91061|Bacilli S Cold-inducible protein YdjO ydjO - - - - - - - - - - - YdjO HPHIIJEP_01349 224308.BSU06260 3.13e-205 573.0 COG0823@1|root,COG0823@2|Bacteria,1U2TZ@1239|Firmicutes,4HSNM@91061|Bacilli,1ZEIS@1386|Bacillus 91061|Bacilli U Involved in the tonB-independent uptake of proteins ydjN - - - - - - - - - - - PD40 HPHIIJEP_01350 224308.BSU06250 1.79e-84 249.0 COG0797@1|root,COG0797@2|Bacteria,1VPGQ@1239|Firmicutes,4HXBZ@91061|Bacilli,1ZG1Y@1386|Bacillus 91061|Bacilli M Lytic transglycolase ydjM - - - - - - - - - - - DPBB_1 HPHIIJEP_01351 224308.BSU06240 1.17e-247 680.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli,1ZBQS@1386|Bacillus 91061|Bacilli E Dehydrogenase ydjL GO:0000721,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.264,1.1.1.303,1.1.1.4 ko:K00004,ko:K00098 ko00650,map00650 - R02855,R02946,R05684,R10504 RC00089,RC00205,RC00525 ko00000,ko00001,ko01000 - - iYO844.BSU06240 ADH_N,ADH_N_assoc,ADH_zinc_N HPHIIJEP_01352 224308.BSU06230 0.0 887.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,1ZAUM@1386|Bacillus 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.26 - - Sugar_tr HPHIIJEP_01353 224308.BSU06220 1.37e-248 682.0 28JN3@1|root,2Z9EI@2|Bacteria,1UYYN@1239|Firmicutes,4HDZ8@91061|Bacilli 91061|Bacilli S Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2 HPHIIJEP_01354 224308.BSU06210 3.61e-203 565.0 COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,4HB4Z@91061|Bacilli,1ZE87@1386|Bacillus 91061|Bacilli S virion core protein (lumpy skin disease virus) ydjI - - - - - - - - - - - Band_7_1,zf-ribbon_3 HPHIIJEP_01355 224308.BSU06200 8.23e-170 475.0 COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,4HN3N@91061|Bacilli,1ZF0N@1386|Bacillus 91061|Bacilli S COG1512 Beta-propeller domains of methanol dehydrogenase type ydjH - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase HPHIIJEP_01356 224308.BSU06190 1.73e-226 626.0 COG1198@1|root,COG1198@2|Bacteria,1UI22@1239|Firmicutes,4HBK5@91061|Bacilli,1ZD8P@1386|Bacillus 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA ydjG - - - - - - - - - - - TF_Zn_Ribbon HPHIIJEP_01357 224308.BSU06180 7.61e-148 417.0 COG1842@1|root,COG1842@2|Bacteria,1UYNB@1239|Firmicutes,4HAMR@91061|Bacilli,1ZBUS@1386|Bacillus 91061|Bacilli KT Phage shock protein A pspA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03969 - - - - ko00000 - - - PspA_IM30 HPHIIJEP_01358 224308.BSU06170 2.45e-220 608.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HCVK@91061|Bacilli,1ZPUT@1386|Bacillus 91061|Bacilli G pfkB family carbohydrate kinase ydjE - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB HPHIIJEP_01359 224308.BSU06160 0.0 879.0 COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HBAI@91061|Bacilli,1ZFRW@1386|Bacillus 91061|Bacilli G MFS/sugar transport protein gutP - - ko:K03292,ko:K16248 - - - - ko00000,ko02000 2.A.2 - - MFS_2 HPHIIJEP_01360 224308.BSU06150 1.51e-258 708.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4IPQ3@91061|Bacilli,1ZRDJ@1386|Bacillus 91061|Bacilli E Dehydrogenase gutB - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N HPHIIJEP_01361 224308.BSU06140 0.0 1599.0 COG0457@1|root,COG0457@2|Bacteria,1VSHC@1239|Firmicutes,4HVBE@91061|Bacilli,1ZM8Y@1386|Bacillus 91061|Bacilli K NB-ARC domain gutR - - ko:K16247 - - - - ko00000,ko03000 - - - NB-ARC HPHIIJEP_01362 1274524.BSONL12_13101 1.22e-189 531.0 COG1073@1|root,COG1073@2|Bacteria,1V1KI@1239|Firmicutes,4HFUC@91061|Bacilli,1ZG04@1386|Bacillus 91061|Bacilli S Abhydrolase domain containing 18 ydjC - - - - - - - - - - - DUF2048 HPHIIJEP_01363 224308.BSU06030 0.0 986.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,1ZBKJ@1386|Bacillus 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 HPHIIJEP_01364 224308.BSU06020 2.14e-58 181.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,1ZGZ1@1386|Bacillus 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 HPHIIJEP_01365 224308.BSU06010 3e-167 468.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,1ZBE1@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi HPHIIJEP_01366 224308.BSU06000 3.2e-37 125.0 29ZQY@1|root,30MRQ@2|Bacteria,1UAKQ@1239|Firmicutes,4IKZC@91061|Bacilli,1ZIH1@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4305) ydiK - - - - - - - - - - - DUF4305 HPHIIJEP_01367 224308.BSU05990 8.73e-162 455.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli,1ZBYZ@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC HPHIIJEP_01368 224308.BSU05980 5.48e-31 108.0 COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 HPHIIJEP_01369 224308.BSU05970 2.14e-148 418.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,1ZANM@1386|Bacillus 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N HPHIIJEP_01370 224308.BSU05960 1.46e-117 336.0 COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4HH39@91061|Bacilli,1ZFIK@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC HPHIIJEP_01371 224308.BSU05950 0.0 1146.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1ZB7Z@1386|Bacillus 91061|Bacilli S ABC transporter ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn HPHIIJEP_01372 224308.BSU05940 1.34e-240 662.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,1ZBT3@1386|Bacillus 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 HPHIIJEP_01373 224308.BSU05930 1.41e-108 312.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,1ZGAT@1386|Bacillus 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 HPHIIJEP_01374 224308.BSU05920 2.69e-158 444.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,1ZC43@1386|Bacillus 91061|Bacilli O COG1214 Inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 HPHIIJEP_01375 224308.BSU05910 7.42e-112 321.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,1ZGBU@1386|Bacillus 91061|Bacilli S ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE HPHIIJEP_01376 224308.BSU05900 2.13e-228 629.0 COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,4HG10@91061|Bacilli,1ZBME@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU05900 AIRS,AIRS_C HPHIIJEP_01379 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01382 1051501.AYTL01000038_gene395 4.02e-201 557.0 COG3546@1|root,COG3546@2|Bacteria,1TP0F@1239|Firmicutes,4HBA9@91061|Bacilli,1ZDFW@1386|Bacillus 91061|Bacilli P Catalase ydhU - - ko:K07217 - - - - ko00000 - - - Mn_catalase HPHIIJEP_01383 224308.BSU05880 1.12e-269 737.0 COG4124@1|root,COG4124@2|Bacteria,1VW9J@1239|Firmicutes,4HWU3@91061|Bacilli,1ZEI1@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 26 family ydhT1 - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - Glyco_hydro_26 HPHIIJEP_01384 224308.BSU05870 1.64e-236 649.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,1ZDJI@1386|Bacillus 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI HPHIIJEP_01385 224308.BSU05860 4.23e-215 593.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,1ZDIZ@1386|Bacillus 91061|Bacilli GK COG1940 Transcriptional regulator sugar kinase gmuE - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK HPHIIJEP_01386 224308.BSU05850 1.83e-169 473.0 COG2188@1|root,COG2188@2|Bacteria,1V0UW@1239|Firmicutes,4HD10@91061|Bacilli,1ZE1N@1386|Bacillus 91061|Bacilli K UTRA ydhQ - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_01387 224308.BSU05840 0.0 974.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family ydhP GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 HPHIIJEP_01388 224308.BSU05830 1.31e-304 832.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1ZBJ7@1386|Bacillus 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC HPHIIJEP_01389 224308.BSU05820 9.74e-67 203.0 COG1447@1|root,COG1447@2|Bacteria,1VA8Z@1239|Firmicutes,4HM1B@91061|Bacilli,1ZHBT@1386|Bacillus 91061|Bacilli G phosphotransferase system ydhN3 - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - iYO844.BSU05820 PTS_IIA HPHIIJEP_01390 224308.BSU05810 1.88e-63 194.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKCQ@91061|Bacilli,1ZQH2@1386|Bacillus 91061|Bacilli G phosphotransferase system ydhM - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB HPHIIJEP_01391 224308.BSU05800 6.3e-255 702.0 COG0477@1|root,COG2814@2|Bacteria,1TRNU@1239|Firmicutes,4HCSX@91061|Bacilli,1ZCJJ@1386|Bacillus 91061|Bacilli EGP COG2814 Arabinose efflux permease ydhL - - ko:K18567 - - - - ko00000,ko02000 2.A.1.2.25 - - MFS_1,Sugar_tr HPHIIJEP_01392 224308.BSU05790 2.59e-126 360.0 COG1388@1|root,COG1388@2|Bacteria,1V3Q9@1239|Firmicutes,4HH9X@91061|Bacilli,1ZGK9@1386|Bacillus 91061|Bacilli M Protein of unknown function (DUF1541) ydhK - - - - - - - - - - - DUF1541 HPHIIJEP_01394 224308.BSU05780 1.63e-232 640.0 COG1078@1|root,COG1078@2|Bacteria,1TQZH@1239|Firmicutes,4HD6U@91061|Bacilli,1ZBN3@1386|Bacillus 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. ydhJ GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD HPHIIJEP_01395 224308.BSU05770 1.32e-108 313.0 COG0454@1|root,COG0454@2|Bacteria,1UHNV@1239|Firmicutes,4IS4R@91061|Bacilli,1ZS7G@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - - - - - - - - - - Acetyltransf_1 HPHIIJEP_01397 224308.BSU05750 2.26e-87 256.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,1ZFK6@1386|Bacillus 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 HPHIIJEP_01398 224308.BSU05740 0.0 903.0 COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,4HA27@91061|Bacilli,1ZB3J@1386|Bacillus 91061|Bacilli P Belongs to the alkaline phosphatase family phoB - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase HPHIIJEP_01399 224308.BSU05730 1.18e-160 451.0 299QV@1|root,2ZWT3@2|Bacteria,1VBIX@1239|Firmicutes,4HI89@91061|Bacilli,1ZEV8@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF4352 HPHIIJEP_01400 224308.BSU05720 1.59e-288 787.0 COG1819@1|root,COG1819@2|Bacteria,1TSPC@1239|Firmicutes,4HB9I@91061|Bacilli,1ZB3Z@1386|Bacillus 91061|Bacilli CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase ydhE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008194,GO:0016740,GO:0016757,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - - - - - - - - - - UDPGT HPHIIJEP_01401 224308.BSU05710 2.1e-308 840.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HB5I@91061|Bacilli,1ZF99@1386|Bacillus 91061|Bacilli M Glycosyl hydrolase ydhD - - - - - - - - - - - Glyco_hydro_18,LysM HPHIIJEP_01402 224308.BSU05700 7.45e-158 442.0 COG1802@1|root,COG1802@2|Bacteria,1V6GK@1239|Firmicutes,4HIN7@91061|Bacilli,1ZFQP@1386|Bacillus 91061|Bacilli K FCD ydhC - - - - - - - - - - - FCD,GntR HPHIIJEP_01403 224308.BSU05690 1.77e-155 438.0 COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,4HGR6@91061|Bacilli,1ZEEX@1386|Bacillus 91061|Bacilli S membrane transporter protein ydhB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07090 - - - - ko00000 - - - TauE HPHIIJEP_01404 224308.BSU05680 4.02e-265 729.0 COG0477@1|root,COG2814@2|Bacteria,1TR6I@1239|Firmicutes,4HBX6@91061|Bacilli,1ZCB7@1386|Bacillus 91061|Bacilli EGP -transporter tcaB - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 HPHIIJEP_01405 224308.BSU05670 1.9e-89 264.0 COG1846@1|root,COG1846@2|Bacteria,1VXGR@1239|Firmicutes,4HX2D@91061|Bacilli,1ZRRD@1386|Bacillus 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR HPHIIJEP_01406 224308.BSU05660 6.42e-147 414.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,1ZAQV@1386|Bacillus 91061|Bacilli C nitroreductase ydgI - - - - - - - - - - - Nitroreductase HPHIIJEP_01407 224308.BSU05650 0.0 1496.0 COG1033@1|root,COG2409@1|root,COG1033@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,1ZCFN@1386|Bacillus 91061|Bacilli S drug exporters of the RND superfamily ydgH - - ko:K06994 - - - - ko00000 - - - MMPL HPHIIJEP_01408 224308.BSU05640 4.85e-103 299.0 COG1846@1|root,COG1846@2|Bacteria,1VGV7@1239|Firmicutes,4HNX9@91061|Bacilli,1ZHGG@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_27,MarR,MarR_2 HPHIIJEP_01409 224308.BSU05630 2.83e-116 333.0 COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes,4HKV1@91061|Bacilli,1ZR49@1386|Bacillus 91061|Bacilli S DinB family - - - - - - - - - - - - DinB HPHIIJEP_01410 224308.BSU05620 0.0 868.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease HPHIIJEP_01411 224308.BSU05610 0.0 1043.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli,1ZBZP@1386|Bacillus 91061|Bacilli S ABC transporter expZ - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn HPHIIJEP_01412 224308.BSU05600 3.15e-108 311.0 COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,1ZFP4@1386|Bacillus 91061|Bacilli K Acetyltransferase yycN - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_01413 224308.BSU05590 1.41e-70 213.0 2F6NF@1|root,33Z4Z@2|Bacteria,1VXVN@1239|Firmicutes,4HXT1@91061|Bacilli,1ZIJV@1386|Bacillus 91061|Bacilli S DoxX-like family - - - - - - - - - - - - DoxX_2 HPHIIJEP_01414 224308.BSU05580 4.92e-127 362.0 COG1309@1|root,COG1309@2|Bacteria,1V50Q@1239|Firmicutes,4HHD5@91061|Bacilli,1ZGFG@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family ydgC GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_01415 224308.BSU05570 4.99e-44 144.0 2EQG8@1|root,33IXY@2|Bacteria,1W1ME@1239|Firmicutes,4I0CE@91061|Bacilli,1ZJH9@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF ydgB - - - - - - - - - - - gerPA HPHIIJEP_01416 224308.BSU05560 1.53e-47 152.0 2EQG8@1|root,33I29@2|Bacteria,1VMF2@1239|Firmicutes,4IAND@91061|Bacilli,1ZJ0K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF ydgA - - - - - - - - - - - gerPA HPHIIJEP_01417 224308.BSU05550 2.2e-90 265.0 COG0071@1|root,COG0071@2|Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family cotP - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - GvpH,HSP20 HPHIIJEP_01418 224308.BSU05540 5.03e-93 275.0 COG2323@1|root,COG2323@2|Bacteria,1V0NU@1239|Firmicutes,4HFHX@91061|Bacilli,1ZQ04@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) ydfS - - - - - - - - - - - DUF421 HPHIIJEP_01419 224308.BSU05540 3.79e-35 127.0 COG2323@1|root,COG2323@2|Bacteria,1V0NU@1239|Firmicutes,4HFHX@91061|Bacilli,1ZQ04@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) ydfS - - - - - - - - - - - DUF421 HPHIIJEP_01420 224308.BSU05530 7.93e-91 270.0 COG2323@1|root,COG2323@2|Bacteria,1V84I@1239|Firmicutes,4HJRH@91061|Bacilli,1ZR7T@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF421) ydfR - - - - - - - - - - - DUF421 HPHIIJEP_01422 1274524.BSONL12_10381 5.33e-39 132.0 2E3GS@1|root,32YFG@2|Bacteria,1VGU9@1239|Firmicutes,4HNWB@91061|Bacilli,1ZHW7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01423 224308.BSU05560 1.97e-20 84.0 2EQG8@1|root,33I29@2|Bacteria,1VMF2@1239|Firmicutes,4IAND@91061|Bacilli,1ZJ0K@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF ydgA - - - - - - - - - - - gerPA HPHIIJEP_01424 224308.BSU05510 7.63e-74 221.0 COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes,4HNQS@91061|Bacilli,1ZJBR@1386|Bacillus 91061|Bacilli CO Thioredoxin ydfQ - - - - - - - - - - - Thioredoxin HPHIIJEP_01425 224308.BSU05500 1.62e-83 247.0 COG2259@1|root,COG2259@2|Bacteria,1V7TX@1239|Firmicutes,4HJ1T@91061|Bacilli,1ZGHR@1386|Bacillus 91061|Bacilli S DoxX ydfP - - ko:K15977 - - - - ko00000 - - - DoxX HPHIIJEP_01426 224308.BSU05490 1.29e-236 649.0 COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZAQY@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ydfO - - ko:K15975 - - - - ko00000 - - - Glyoxalase HPHIIJEP_01427 224308.BSU05480 3.71e-140 396.0 COG0778@1|root,COG0778@2|Bacteria,1V1NQ@1239|Firmicutes,4HHS6@91061|Bacilli,1ZE4B@1386|Bacillus 91061|Bacilli C nitroreductase ydfN - - ko:K15976 - - - - ko00000,ko01000 - - - Nitroreductase HPHIIJEP_01428 224308.BSU05470 2.12e-198 551.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family ydfM - - - - - - - - - - - Cation_efflux,ZT_dimer HPHIIJEP_01429 224308.BSU05460 2.91e-187 521.0 COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,4HGJF@91061|Bacilli,1ZQ1T@1386|Bacillus 91061|Bacilli K Bacterial transcription activator, effector binding domain - - - - - - - - - - - - GyrI-like,MerR_1 HPHIIJEP_01430 224308.BSU05450 2.27e-150 424.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,1ZBSK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 HPHIIJEP_01431 224308.BSU05430 0.0 1330.0 COG2409@1|root,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HCW1@91061|Bacilli,1ZDKH@1386|Bacillus 91061|Bacilli S drug exporters of the RND superfamily ydfJ - - ko:K06994,ko:K11625 ko02020,map02020 - - - ko00000,ko00001 - - - MMPL HPHIIJEP_01432 224308.BSU05420 2.3e-142 402.0 COG2197@1|root,COG2197@2|Bacteria,1V207@1239|Firmicutes,4HG4K@91061|Bacilli,1ZGF3@1386|Bacillus 91061|Bacilli K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain ydfI - - ko:K11624 ko02020,map02020 M00484 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_01433 224308.BSU05410 1.31e-249 689.0 COG4585@1|root,COG4585@2|Bacteria,1UYVE@1239|Firmicutes,4HGNS@91061|Bacilli,1ZMNB@1386|Bacillus 91061|Bacilli T Histidine kinase ydfH - 2.7.13.3 ko:K11623 ko02020,map02020 M00484 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 HPHIIJEP_01434 224308.BSU05400 3.92e-104 300.0 COG2128@1|root,COG2128@2|Bacteria,1V97G@1239|Firmicutes,4HHFF@91061|Bacilli,1ZFPE@1386|Bacillus 91061|Bacilli S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD HPHIIJEP_01435 224308.BSU05390 1.5e-158 444.0 COG0640@1|root,COG0640@2|Bacteria,1V007@1239|Firmicutes,4HDXJ@91061|Bacilli,1ZDVN@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor ydfF GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 HPHIIJEP_01436 224308.BSU05380 9.91e-150 421.0 COG1853@1|root,COG1853@2|Bacteria,1TRI4@1239|Firmicutes,4HE21@91061|Bacilli,1ZFZX@1386|Bacillus 91061|Bacilli S Flavin reductase like domain ydfE - - - - - - - - - - - Flavin_Reduct HPHIIJEP_01437 224308.BSU05370 0.0 937.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB1C@91061|Bacilli,1ZASA@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydfD - - ko:K18907 - M00700,M00702 - - ko00000,ko00002,ko01504,ko03000 - - - Aminotran_1_2,GntR HPHIIJEP_01438 224308.BSU05360 2.8e-190 531.0 COG0697@1|root,COG0697@2|Bacteria,1TSKX@1239|Firmicutes,4HBPE@91061|Bacilli,1ZDEA@1386|Bacillus 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA HPHIIJEP_01439 1051501.AYTL01000031_gene1392 2.25e-156 441.0 COG0745@1|root,COG0745@2|Bacteria,1V18V@1239|Firmicutes,4HE9Y@91061|Bacilli,1ZMTB@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_01440 1274524.BSONL12_02072 1.86e-286 790.0 COG0642@1|root,COG2205@2|Bacteria,1V12H@1239|Firmicutes,4HETS@91061|Bacilli,1ZH9B@1386|Bacillus 91061|Bacilli T GHKL domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA HPHIIJEP_01441 1051501.AYTL01000031_gene1394 4.7e-199 558.0 28IY1@1|root,2Z8VV@2|Bacteria,1U7HY@1239|Firmicutes,4HFC5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01442 1051501.AYTL01000031_gene1395 2.4e-156 442.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HEQR@91061|Bacilli,1ZEGM@1386|Bacillus 91061|Bacilli G deacetylase nodB1 - - - - - - - - - - - Cu_amine_oxidN1,Polysacc_deac_1 HPHIIJEP_01443 1051501.AYTL01000031_gene1396 4.78e-191 532.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4IQSP@91061|Bacilli,1ZRN9@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - LytR_cpsA_psr HPHIIJEP_01444 224308.BSU05350 1.28e-183 511.0 COG1670@1|root,COG1670@2|Bacteria,1V8DB@1239|Firmicutes,4IPY3@91061|Bacilli,1ZREJ@1386|Bacillus 91061|Bacilli J GNAT acetyltransferase - - - - - - - - - - - - GNAT_acetyltran HPHIIJEP_01445 224308.BSU05340 1.75e-294 806.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump arsB - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB HPHIIJEP_01446 224308.BSU05330 3e-75 224.0 COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HM9M@91061|Bacilli,1ZHC7@1386|Bacillus 91061|Bacilli K transcriptional arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03892,ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 HPHIIJEP_01447 224308.BSU05280 6.56e-194 539.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) ydeO - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_01448 224308.BSU05270 1.19e-71 215.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HNAK@91061|Bacilli 91061|Bacilli K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR HPHIIJEP_01449 224308.BSU05260 8.06e-134 379.0 COG3545@1|root,COG3545@2|Bacteria,1V6R4@1239|Firmicutes,4HVF4@91061|Bacilli 91061|Bacilli S Serine hydrolase - - - ko:K07002 - - - - ko00000 - - - Ser_hydrolase HPHIIJEP_01450 224308.BSU05250 3.68e-97 282.0 COG2030@1|root,COG2030@2|Bacteria,1VFE5@1239|Firmicutes,4HHCB@91061|Bacilli,1ZHGT@1386|Bacillus 91061|Bacilli I N-terminal half of MaoC dehydratase ydeM1 - - - - - - - - - - - MaoC_dehydratas HPHIIJEP_01451 224308.BSU05240 0.0 933.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,1ZB5R@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ydeL - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR HPHIIJEP_01452 224308.BSU05230 2.21e-195 543.0 COG0697@1|root,COG0697@2|Bacteria,1VQY5@1239|Firmicutes,4HTD3@91061|Bacilli,1ZDUK@1386|Bacillus 91061|Bacilli EG -transporter ydeK - - - - - - - - - - - EamA HPHIIJEP_01453 224308.BSU05220 2.79e-146 413.0 291NR@1|root,2ZP8Y@2|Bacteria,1V43E@1239|Firmicutes,4HHQD@91061|Bacilli,1ZH81@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01454 224308.BSU05210 4.53e-132 375.0 COG4430@1|root,COG4430@2|Bacteria,1UYP9@1239|Firmicutes,4HDZD@91061|Bacilli,1ZDB7@1386|Bacillus 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated ydeI - - - - - - - - - - - DUF1801,OmdA HPHIIJEP_01455 224308.BSU05200 7.89e-71 215.0 2E0VF@1|root,32WCQ@2|Bacteria,1VASP@1239|Firmicutes,4HKEM@91061|Bacilli,1ZJHA@1386|Bacillus 91061|Bacilli - - ydeH - - - - - - - - - - - - HPHIIJEP_01456 224308.BSU05190 6.57e-278 763.0 COG0477@1|root,COG0477@2|Bacteria,1UHS2@1239|Firmicutes,4IS7X@91061|Bacilli,1ZC9K@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily ydeG - - - - - - - - - - - MFS_1,Sugar_tr,TRI12 HPHIIJEP_01457 224308.BSU05180 0.0 895.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HD5A@91061|Bacilli,1ZD2Q@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - - - - - - - - - - Aminotran_1_2,GntR HPHIIJEP_01458 224308.BSU05170 2.26e-210 581.0 COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,1ZAUV@1386|Bacillus 91061|Bacilli K AraC family transcriptional regulator ydeE GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 HPHIIJEP_01459 224308.BSU05160 5.82e-223 615.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,1ZCQ3@1386|Bacillus 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily ydeD - - - - - - - - - - - EamA HPHIIJEP_01460 224308.BSU05150 1.47e-207 574.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UYFB@1239|Firmicutes,4IPW9@91061|Bacilli,1ZREI@1386|Bacillus 91061|Bacilli K AraC-like ligand binding domain - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 HPHIIJEP_01461 224308.BSU05140 6.72e-41 135.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination ydzE - - - - - - - - - - - EamA HPHIIJEP_01462 224308.BSU05130 3.57e-103 298.0 COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,4HI9J@91061|Bacilli,1ZG97@1386|Bacillus 91061|Bacilli K Transcription factor ydeB - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF HPHIIJEP_01463 224308.BSU05120 4.22e-41 135.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHSU@1386|Bacillus 91061|Bacilli K Cold shock cspL - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HPHIIJEP_01464 720555.BATR1942_00140 2.02e-246 676.0 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase HPHIIJEP_01466 386043.lwe2088 2.51e-45 172.0 2DPD2@1|root,331JF@2|Bacteria,1VHGV@1239|Firmicutes,4HPWD@91061|Bacilli,26MJ3@186820|Listeriaceae 91061|Bacilli S Putative amidase domain - - - - - - - - - - - - Amidase_6,SH3_8 HPHIIJEP_01467 720555.BATR1942_06570 5.84e-179 525.0 COG5444@1|root,COG5444@2|Bacteria,1V897@1239|Firmicutes,4HIMS@91061|Bacilli,1ZIHP@1386|Bacillus 91061|Bacilli L A nuclease of the HNH/ENDO VII superfamily with conserved LHH - - - ko:K21487 - - - - ko00000,ko01000,ko02048 - - - EndoU_bacteria,LHH,LXG HPHIIJEP_01468 44251.PDUR_04760 9.42e-57 182.0 2E1G6@1|root,32WUQ@2|Bacteria,1VE62@1239|Firmicutes,4HND0@91061|Bacilli,273CF@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01469 1051501.AYTL01000030_gene2755 1.42e-61 193.0 2E17N@1|root,32WNB@2|Bacteria,1VDC9@1239|Firmicutes,4IT61@91061|Bacilli,1ZH8Q@1386|Bacillus 91061|Bacilli S SMI1-KNR4 cell-wall - - - ko:K21488 - - - - ko00000,ko02048 - - - SUKH_5 HPHIIJEP_01470 880070.Cycma_0619 3.15e-144 450.0 COG3613@1|root,COG3613@2|Bacteria 2|Bacteria F nucleoside 2-deoxyribosyltransferase - - 2.7.1.74,2.7.1.76 ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 - R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - - HPHIIJEP_01478 224308.BSU04790 1.07e-107 310.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,1ZG8Y@1386|Bacillus 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT HPHIIJEP_01479 224308.BSU04780 0.0 1356.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1ZC3T@1386|Bacillus 91061|Bacilli K COG2183 Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF HPHIIJEP_01480 224308.BSU04770 1.79e-100 291.0 COG1846@1|root,COG1846@2|Bacteria,1VCDY@1239|Firmicutes,4HM32@91061|Bacilli,1ZN3E@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_01481 224308.BSU04760 3.11e-105 303.0 COG1673@1|root,COG1673@2|Bacteria,1VAXR@1239|Firmicutes,4HKYH@91061|Bacilli,1ZGHM@1386|Bacillus 91061|Bacilli S EVE domain ydcG - - - - - - - - - - - EVE HPHIIJEP_01484 224308.BSU04740 3.75e-141 398.0 COG2208@1|root,COG2208@2|Bacteria,1V0BN@1239|Firmicutes,4HECS@91061|Bacilli,1ZEVQ@1386|Bacillus 91061|Bacilli KT Sigma factor PP2C-like phosphatases rsbX GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896 3.1.3.3 ko:K05518 - - - - ko00000,ko01000,ko03021 - - - PP2C_2,SpoIIE HPHIIJEP_01485 224308.BSU04730 1.55e-178 498.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HBIW@91061|Bacilli,1ZBAP@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigB GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043620,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03090 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 HPHIIJEP_01486 224308.BSU04720 8.3e-110 316.0 COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HM6Z@91061|Bacilli,1ZQQZ@1386|Bacillus 91061|Bacilli F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) rsbW GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 2.7.11.1 ko:K04757 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c_2 HPHIIJEP_01487 224308.BSU04710 3.98e-70 211.0 COG1366@1|root,COG1366@2|Bacteria,1VER8@1239|Firmicutes,4HP2I@91061|Bacilli,1ZIDN@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family rsbV - - ko:K04749 - - - - ko00000,ko03021 - - - STAS,STAS_2 HPHIIJEP_01488 224308.BSU04700 1.08e-242 666.0 COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,4HAF6@91061|Bacilli,1ZBIB@1386|Bacillus 91061|Bacilli KT phosphatase rsbU - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - RsbU_N,SpoIIE HPHIIJEP_01489 224308.BSU04690 2.45e-89 262.0 COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli,1ZG7T@1386|Bacillus 91061|Bacilli T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) rsbT - 2.7.11.1 ko:K17752 - - - - ko00000,ko01000,ko01001,ko03021 - - - HATPase_c,HATPase_c_2 HPHIIJEP_01490 224308.BSU04680 1.8e-74 223.0 COG1366@1|root,COG1366@2|Bacteria,1V7FB@1239|Firmicutes,4HIQ6@91061|Bacilli,1ZGH2@1386|Bacillus 91061|Bacilli T antagonist rsbS - - ko:K17762 - - - - ko00000,ko03021 - - - STAS HPHIIJEP_01491 224308.BSU04670 8.58e-184 512.0 COG1366@1|root,COG1366@2|Bacteria,1UGQT@1239|Firmicutes,4HCRH@91061|Bacilli,1ZBRY@1386|Bacillus 91061|Bacilli T Positive regulator of sigma-B rsbR - - ko:K17763 - - - - ko00000,ko03021 - - - Rsbr_N,STAS HPHIIJEP_01492 224308.BSU04660 4.34e-75 224.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,1ZG8R@1386|Bacillus 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin HPHIIJEP_01493 224308.BSU04650 9.49e-57 176.0 COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,4HKPU@91061|Bacilli,1ZGYI@1386|Bacillus 91061|Bacilli K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain ndoAI GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K07723 - - - - ko00000,ko02048,ko03000 - - - RHH_1 HPHIIJEP_01494 224308.BSU04640 1.77e-282 771.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,1ZCW9@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N HPHIIJEP_01495 224308.BSU04630 4.66e-234 646.0 COG2834@1|root,COG2834@2|Bacteria,1TSRE@1239|Firmicutes,4HBCH@91061|Bacilli,1ZBE6@1386|Bacillus 91061|Bacilli M COG2834 Outer membrane lipoprotein-sorting protein ydcC - - - - - - - - - - - DUF4367 HPHIIJEP_01496 224308.BSU04620 1.6e-77 231.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,1ZI02@1386|Bacillus 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS HPHIIJEP_01497 224308.BSU04610 5.12e-139 393.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZCEK@1386|Bacillus 91061|Bacilli S membrane protein (homolog of Drosophila rhomboid) ydcA - - - - - - - - - - - Rhomboid HPHIIJEP_01498 224308.BSU04600 0.0 927.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,1ZBIF@1386|Bacillus 91061|Bacilli S Membrane ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 HPHIIJEP_01499 224308.BSU04590 2.12e-107 310.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HPTD@91061|Bacilli,1ZQR1@1386|Bacillus 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 HPHIIJEP_01500 224308.BSU04580 0.0 920.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,1ZAPP@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C HPHIIJEP_01501 224308.BSU04570 0.0 892.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,1ZCC3@1386|Bacillus 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HPHIIJEP_01502 224308.BSU04560 3.58e-257 705.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,1ZDA3@1386|Bacillus 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N HPHIIJEP_01503 224308.BSU04550 4.19e-75 224.0 COG0526@1|root,COG0526@2|Bacteria,1VA84@1239|Firmicutes,4HKCD@91061|Bacilli,1ZHXM@1386|Bacillus 91061|Bacilli CO Thioredoxin ydbP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin HPHIIJEP_01504 224308.BSU04540 2.72e-202 560.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli,1ZAPN@1386|Bacillus 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer HPHIIJEP_01506 224308.BSU04530 1.49e-26 97.4 29SEI@1|root,30DJB@2|Bacteria,1UBCP@1239|Firmicutes,4IMRH@91061|Bacilli,1ZKP6@1386|Bacillus 91061|Bacilli S Fur-regulated basic protein B - - - - - - - - - - - - Fur_reg_FbpB HPHIIJEP_01507 224308.BSU04520 1.5e-279 763.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HBTP@91061|Bacilli,1ZATT@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase ydbM - - - - - - - - - - iYO844.BSU04520 Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N HPHIIJEP_01508 224308.BSU04510 9.32e-70 211.0 29RJA@1|root,30CND@2|Bacteria,1UA4S@1239|Firmicutes,4IKF0@91061|Bacilli,1ZGT1@1386|Bacillus 91061|Bacilli - - ydbL - - - - - - - - - - - - HPHIIJEP_01509 224308.BSU04500 2.45e-158 446.0 COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,1ZDPM@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component ydbK - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 HPHIIJEP_01510 224308.BSU04490 2.66e-218 602.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,1ZB4N@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein ydbJ - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01511 224308.BSU04480 1.32e-230 637.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,1ZBJD@1386|Bacillus 91061|Bacilli S AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport HPHIIJEP_01512 224308.BSU04470 2.1e-288 789.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZBKK@1386|Bacillus 91061|Bacilli U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family dctA - - ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 - iYO844.BSU10220 SDF HPHIIJEP_01513 224308.BSU04460 3.39e-155 436.0 COG4565@1|root,COG4565@2|Bacteria,1V49R@1239|Firmicutes,4HHD4@91061|Bacilli,1ZDGY@1386|Bacillus 91061|Bacilli T COG4565 Response regulator of citrate malate metabolism dctR - - ko:K02475,ko:K11692 ko02020,map02020 M00489 - - ko00000,ko00001,ko00002,ko02022 - - - FaeA,HTH_11,HTH_DeoR,HTH_IclR,Response_reg HPHIIJEP_01514 224308.BSU04450 0.0 1018.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism dctS - 2.7.13.3 ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 M00487,M00489,M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HATPase_c_5,PAS,PAS_10,PAS_8,PAS_9,SPOB_a,sCache_3_2 HPHIIJEP_01515 224308.BSU04440 3.66e-253 694.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HD0U@91061|Bacilli,1ZCY6@1386|Bacillus 91061|Bacilli G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component dctB - - - - - - - - - - - DctP HPHIIJEP_01516 224308.BSU04430 6.41e-197 545.0 COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,4H9XR@91061|Bacilli,1ZBZ9@1386|Bacillus 91061|Bacilli P Catalase ydbD GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - ko:K07217 - - - - ko00000 - - - Mn_catalase HPHIIJEP_01517 224308.BSU04420 1.49e-81 241.0 COG2329@1|root,COG2329@2|Bacteria,1VHZ1@1239|Firmicutes,4HP36@91061|Bacilli,1ZHXX@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4937 ydbC - - - - - - - - - - - ABM,Cupin_2,DUF4937 HPHIIJEP_01518 224308.BSU04410 7.58e-79 234.0 COG0662@1|root,COG0662@2|Bacteria,1VI5Z@1239|Firmicutes,4HSX4@91061|Bacilli,1ZGZ3@1386|Bacillus 91061|Bacilli G Cupin domain ydbB - - - - - - - - - - - Cupin_2 HPHIIJEP_01519 224308.BSU04400 8.37e-11 62.4 COG3729@1|root,COG3729@2|Bacteria,1V71P@1239|Firmicutes,4HJ8A@91061|Bacilli,1ZGZA@1386|Bacillus 91061|Bacilli S general stress protein gsiB - - ko:K06884 - - - - ko00000 - - - KGG,LEA_5 HPHIIJEP_01520 224308.BSU04390 1.38e-186 519.0 COG2217@1|root,COG2217@2|Bacteria,1UHSD@1239|Firmicutes,4IS9K@91061|Bacilli,1ZS3Q@1386|Bacillus 91061|Bacilli P EcsC protein family ydbA - - - - - - - - - - - EcsC HPHIIJEP_01521 224308.BSU04380 2.25e-100 291.0 COG4876@1|root,COG4876@2|Bacteria,1V946@1239|Firmicutes,4IRQ3@91061|Bacilli,1ZRWN@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2188) ydaT - - - - - - - - - - - DUF2188 HPHIIJEP_01522 224308.BSU04370 1.67e-42 140.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,1ZJBG@1386|Bacillus 91061|Bacilli S membrane ydaS - - - - - - - - - - - Transgly_assoc HPHIIJEP_01523 224308.BSU04360 3.9e-286 784.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,1ZCHH@1386|Bacillus 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - iYO844.BSU04360 Nramp HPHIIJEP_01524 224308.BSU04359 6.14e-53 166.0 29RT2@1|root,30CWY@2|Bacteria,1UAHA@1239|Firmicutes,4IKVS@91061|Bacilli,1ZHYE@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01526 1385514.N782_00520 2.18e-90 279.0 COG3011@1|root,COG3011@2|Bacteria,1V3RN@1239|Firmicutes,4HH7R@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria sdpB - - - - - - - - - - - DUF393,VKG_Carbox HPHIIJEP_01527 1385514.N782_00525 1.84e-34 127.0 2EIE2@1|root,33C5F@2|Bacteria,1VCC4@1239|Firmicutes,4HM6A@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01529 224308.BSU04340 0.0 1142.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,1ZB01@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family ydaP - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HPHIIJEP_01530 224308.BSU04330 4.21e-100 290.0 COG0494@1|root,COG0494@2|Bacteria,1VQCD@1239|Firmicutes,4IPY2@91061|Bacilli,1ZHWQ@1386|Bacillus 91061|Bacilli L Belongs to the Nudix hydrolase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX HPHIIJEP_01531 224308.BSU04320 0.0 1148.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,1ZC7Q@1386|Bacillus 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 HPHIIJEP_01532 224308.BSU04310 0.0 1320.0 28HGC@1|root,2Z7S8@2|Bacteria,1V3ZA@1239|Firmicutes,4IRWX@91061|Bacilli,1ZFHW@1386|Bacillus 91061|Bacilli S Bacterial cellulose synthase subunit ydaN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - BcsB HPHIIJEP_01533 224308.BSU04300 1.93e-304 830.0 COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli,1ZE8G@1386|Bacillus 91061|Bacilli M Glycosyl transferase family group 2 ydaM - - - - - - - - - - - Glyco_tranf_2_3 HPHIIJEP_01534 224308.BSU04290 0.0 1101.0 COG5298@1|root,COG5298@2|Bacteria,1TSDC@1239|Firmicutes,4HD1Q@91061|Bacilli,1ZDYW@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2334) ydaL - - - - - - - - - - - DUF2334 HPHIIJEP_01535 224308.BSU04280 6.34e-193 536.0 COG2199@1|root,COG3706@2|Bacteria,1VHAN@1239|Firmicutes,4HQWC@91061|Bacilli,1ZFFR@1386|Bacillus 91061|Bacilli T Diguanylate cyclase, GGDEF domain ydaK - - - - - - - - - - - GGDEF HPHIIJEP_01536 224308.BSU04270 2.72e-261 716.0 COG3405@1|root,COG3405@2|Bacteria,1V4ZT@1239|Firmicutes,4HG8R@91061|Bacilli,1ZR17@1386|Bacillus 91061|Bacilli M Belongs to the glycosyl hydrolase 8 (cellulase D) family ydaJ - - - - - - - - - - - Glyco_hydro_8 HPHIIJEP_01537 224308.BSU04260 0.0 1424.0 COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,1ZBEG@1386|Bacillus 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim HPHIIJEP_01538 224308.BSU04250 3.95e-98 285.0 COG1522@1|root,COG1522@2|Bacteria,1V93E@1239|Firmicutes,4IS27@91061|Bacilli,1ZS0N@1386|Bacillus 91061|Bacilli K Transcriptional regulator lrpC GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type HPHIIJEP_01539 224308.BSU04240 1.09e-61 189.0 COG0477@1|root,COG2814@2|Bacteria,1VGN4@1239|Firmicutes,4HNVP@91061|Bacilli,1ZIWN@1386|Bacillus 91061|Bacilli EGP Domain of unknown function (DUF3817) ydzA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF3817 HPHIIJEP_01540 224308.BSU04230 5.35e-178 497.0 28NMK@1|root,2ZBN3@2|Bacteria,1TT4K@1239|Firmicutes,4HBFT@91061|Bacilli,1ZCHB@1386|Bacillus 91061|Bacilli U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane amj - - - - - - - - - - - Amj HPHIIJEP_01541 224308.BSU04220 1.06e-100 291.0 COG3871@1|root,COG3871@2|Bacteria,1V6MX@1239|Firmicutes,4HIYZ@91061|Bacilli,1ZH2Z@1386|Bacillus 91061|Bacilli S general stress protein ydaG - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like HPHIIJEP_01542 224308.BSU04210 1.1e-132 375.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,1ZEC8@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HPHIIJEP_01543 224308.BSU04200 2.36e-126 358.0 COG1917@1|root,COG1917@2|Bacteria,1UI65@1239|Firmicutes,4ISF6@91061|Bacilli,1ZGCF@1386|Bacillus 91061|Bacilli S Cupin 2, conserved barrel domain protein ydaE - 5.3.1.15 ko:K09988 ko00040,map00040 - R01898 RC00516 ko00000,ko00001,ko01000 - - - Lyx_isomer HPHIIJEP_01544 224308.BSU04190 1.25e-205 568.0 COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,4HB8Y@91061|Bacilli,1ZAS0@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ydaD - - - - - - - - - - - adh_short_C2 HPHIIJEP_01545 224308.BSU04180 2.46e-128 365.0 COG0500@1|root,COG2226@2|Bacteria,1V9BF@1239|Firmicutes,4HK9K@91061|Bacilli,1ZGGF@1386|Bacillus 91061|Bacilli Q Methyltransferase domain ydaC - - - - - - - - - - - Methyltransf_11,Methyltransf_25 HPHIIJEP_01546 224308.BSU04170 0.0 1008.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZEIH@1386|Bacillus 91061|Bacilli IQ acyl-CoA ligase ydaB - - - - - - - - - - - AMP-binding,AMP-binding_C HPHIIJEP_01547 224308.BSU04160 0.0 1305.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,1ZBYI@1386|Bacillus 91061|Bacilli K transcriptional regulator, MtlR mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB HPHIIJEP_01548 224308.BSU04150 3e-220 607.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,1ZD8D@1386|Bacillus 91061|Bacilli S Oxidoreductase ycsN - - - - - - - - - - - Aldo_ket_red HPHIIJEP_01549 224308.BSU04140 0.0 1318.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4H9MT@91061|Bacilli,1ZAX9@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpC - 3.4.16.4 ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 M00625 - - ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 - - - MecA_N,PBP_dimer,Transpeptidase HPHIIJEP_01550 224308.BSU04130 7.67e-66 199.0 COG2329@1|root,COG2329@2|Bacteria,1VCZF@1239|Firmicutes,4HMH1@91061|Bacilli,1ZH5C@1386|Bacillus 91061|Bacilli S biosynthesis yczJ - - - - - - - - - - - ABM HPHIIJEP_01552 224308.BSU04110 6.66e-151 424.0 COG2755@1|root,COG2755@2|Bacteria,1VAXZ@1239|Firmicutes,4HNDB@91061|Bacilli,1ZETN@1386|Bacillus 91061|Bacilli E anatomical structure formation involved in morphogenesis ycsK GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575 - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_01553 224308.BSU04100 1.55e-170 477.0 COG1414@1|root,COG1414@2|Bacteria,1TQS2@1239|Firmicutes,4HBYR@91061|Bacilli,1ZDMV@1386|Bacillus 91061|Bacilli K Transcriptional regulator kipR GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HTH_IclR,IclR HPHIIJEP_01554 224308.BSU04090 2.72e-236 650.0 COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 2 kipA - - ko:K06350 - - - - ko00000 - - - CT_A_B HPHIIJEP_01555 224308.BSU04080 2.8e-170 475.0 COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,1ZDVS@1386|Bacillus 91061|Bacilli E Allophanate hydrolase subunit 1 kipI - - ko:K06351 - - - - ko00000 - - - CT_C_D HPHIIJEP_01556 224308.BSU04070 6.72e-188 521.0 COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,4HCWD@91061|Bacilli,1ZB87@1386|Bacillus 91061|Bacilli S Belongs to the D-glutamate cyclase family ycsI - - - - - - - - - - - DUF1445 HPHIIJEP_01557 224308.BSU04060 2.78e-273 749.0 COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,1ZC68@1386|Bacillus 91061|Bacilli P COG1914 Mn2 and Fe2 transporters of the NRAMP family ycsG - - - - - - - - - - - Nramp HPHIIJEP_01558 224308.BSU04050 1.05e-178 498.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,1ZC6W@1386|Bacillus 91061|Bacilli S Belongs to the UPF0271 (lamB) family ycsF - - ko:K07160 - - - - ko00000 - - - LamB_YcsF HPHIIJEP_01559 224308.BSU04040 1.9e-177 494.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HFXT@91061|Bacilli,1ZQ4E@1386|Bacillus 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 HPHIIJEP_01561 224308.BSU04030 2.68e-87 256.0 COG0764@1|root,COG0764@2|Bacteria,1VXZP@1239|Firmicutes,4HXDJ@91061|Bacilli,1ZNA6@1386|Bacillus 91061|Bacilli I FabA-like domain ycsD - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA HPHIIJEP_01562 224308.BSU04020 1.32e-24 96.7 COG0412@1|root,COG0412@2|Bacteria,1V78Q@1239|Firmicutes,4HDAM@91061|Bacilli,1ZFXV@1386|Bacillus 91061|Bacilli Q COG0412 Dienelactone hydrolase and related enzymes - - - - - - - - - - - - DLH HPHIIJEP_01563 224308.BSU04010 1.25e-96 283.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZGNJ@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 HPHIIJEP_01565 224308.BSU04000 1.01e-256 703.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HA76@91061|Bacilli,1ZB1V@1386|Bacillus 91061|Bacilli CE Tartrate dehydrogenase ycsA - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh HPHIIJEP_01566 224308.BSU03990 8.87e-268 733.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,1ZD4H@1386|Bacillus 91061|Bacilli G COG0246 Mannitol-1-phosphate altronate dehydrogenases mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C HPHIIJEP_01567 224308.BSU03982 8.3e-95 276.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,1ZETZ@1386|Bacillus 91061|Bacilli G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 HPHIIJEP_01568 224308.BSU03981 0.0 886.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,1ZC81@1386|Bacillus 91061|Bacilli G COG2213 Phosphotransferase system, mannitol-specific IIBC component mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB HPHIIJEP_01569 1051501.AYTL01000031_gene1485 4.67e-75 224.0 2C03Z@1|root,30154@2|Bacteria,1U8TT@1239|Firmicutes,4IIS6@91061|Bacilli,1ZKJI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01570 224308.BSU03960 1.22e-137 389.0 COG1349@1|root,COG1349@2|Bacteria,1V2NI@1239|Firmicutes,4HG3I@91061|Bacilli,1ZGG8@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism ycnK - - ko:K21601 - - - - ko00000,ko03000 - - - HTH_DeoR,NosL HPHIIJEP_01571 224308.BSU03950 0.0 1056.0 COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,1ZEHB@1386|Bacillus 91061|Bacilli P protein, homolog of Cu resistance protein CopC ycnJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K14166 - - - - ko00000,ko02000 - - - CopC,CopD,YtkA HPHIIJEP_01572 224308.BSU03940 8.06e-134 380.0 COG4549@1|root,COG4549@2|Bacteria,1V509@1239|Firmicutes,4HH2V@91061|Bacilli,1ZGDU@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ycnI - - - - - - - - - - - DUF1775 HPHIIJEP_01573 224308.BSU03930 5.9e-187 519.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZD11@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - iYO844.BSU03930 adh_short_C2 HPHIIJEP_01574 224308.BSU03920 1.67e-190 530.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,1ZE1R@1386|Bacillus 91061|Bacilli U Glucose uptake glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport HPHIIJEP_01575 224308.BSU03910 0.0 914.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively gabD GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_01576 224308.BSU03900 9.35e-311 847.0 COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,4H9M7@91061|Bacilli,1ZAZ9@1386|Bacillus 91061|Bacilli E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family gabT GO:0003674,GO:0003824,GO:0003867,GO:0008483,GO:0016740,GO:0016769 2.6.1.19,2.6.1.22 ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648,R04188 RC00006,RC00062,RC00160 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 HPHIIJEP_01577 224308.BSU03890 0.0 942.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HB2U@91061|Bacilli,1ZB5R@1386|Bacillus 91061|Bacilli K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs gabR - - ko:K00375 - - - - ko00000,ko03000 - - - Aminotran_1_2,GntR HPHIIJEP_01578 224308.BSU03880 6.51e-69 208.0 COG0640@1|root,COG0640@2|Bacteria,1U4AD@1239|Firmicutes,4HZN5@91061|Bacilli,1ZQGK@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor yczG GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_5 HPHIIJEP_01579 224308.BSU03870 1.68e-60 186.0 COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,1ZJAH@1386|Bacillus 91061|Bacilli S Monooxygenase ycnE GO:0003674,GO:0003824 - - - - - - - - - - ABM HPHIIJEP_01580 224308.BSU03860 2.12e-174 486.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus 91061|Bacilli C Oxidoreductase - - 1.5.1.39 ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 - R05705,R05706,R08014,R08017,R08042 RC00126,RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase HPHIIJEP_01581 224308.BSU03850 1.76e-199 553.0 COG1309@1|root,COG1309@2|Bacteria,1V783@1239|Firmicutes,4HIR7@91061|Bacilli,1ZFCZ@1386|Bacillus 91061|Bacilli K Transcriptional regulator ycnC GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_01582 224308.BSU03840 0.0 874.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,1ZAXQ@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 HPHIIJEP_01583 224308.BSU03830 1.64e-212 588.0 COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli,1ZB26@1386|Bacillus 91061|Bacilli P COG4607 ABC-type enterochelin transport system, periplasmic component yclQ GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU03830 Peripla_BP_2 HPHIIJEP_01584 224308.BSU03820 2.29e-175 489.0 COG4604@1|root,COG4604@2|Bacteria,1UHP5@1239|Firmicutes,4HBJE@91061|Bacilli,1ZB9F@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein yclP - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran HPHIIJEP_01585 224308.BSU03810 3.16e-209 580.0 COG4605@1|root,COG4605@2|Bacteria,1TP3V@1239|Firmicutes,4HAHE@91061|Bacilli,1ZB2F@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yclO - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_01586 224308.BSU03800 1.09e-205 571.0 COG4606@1|root,COG4606@2|Bacteria,1TSQX@1239|Firmicutes,4H9P2@91061|Bacilli,1ZB32@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily yclN - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_01587 224308.BSU03790 0.0 877.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,1ZBR5@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 HPHIIJEP_01589 1121090.KB894689_gene383 1.58e-05 43.5 29S6R@1|root,30DB9@2|Bacteria,1UB3Q@1239|Firmicutes,4IMGB@91061|Bacilli,1ZK3F@1386|Bacillus 91061|Bacilli S Protein of unknown function (Tiny_TM_bacill) - - - - - - - - - - - - Tiny_TM_bacill HPHIIJEP_01591 326423.RBAM_019730 2.18e-97 301.0 COG0457@1|root,COG0457@2|Bacteria,1W0TS@1239|Firmicutes,4HZ05@91061|Bacilli,1ZCCQ@1386|Bacillus 91061|Bacilli S aspartate phosphatase rapA1 - - ko:K06359,ko:K06361 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - TPR_12,TPR_8 HPHIIJEP_01592 224308.BSU03760 0.0 897.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4IS6U@91061|Bacilli,1ZS7E@1386|Bacillus 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA HPHIIJEP_01593 224308.BSU03750 2.23e-165 462.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,1ZD4W@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_01594 224308.BSU03740 4.16e-275 761.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli,1ZBS7@1386|Bacillus 91061|Bacilli V ABC transporter (permease) YclI yclI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HPHIIJEP_01595 224308.BSU03730 1.38e-154 434.0 COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HD2M@91061|Bacilli,1ZPYV@1386|Bacillus 91061|Bacilli P ABC transporter yclH - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01596 224308.BSU03720 2.25e-245 676.0 COG1457@1|root,COG1457@2|Bacteria,1UI3Y@1239|Firmicutes,4ISCI@91061|Bacilli,1ZS7D@1386|Bacillus 91061|Bacilli F Spore germination protein gerKB - - ko:K06296 - - - - ko00000,ko02000 2.A.3.9.3 - - Spore_permease HPHIIJEP_01597 224308.BSU03710 9.59e-287 784.0 2DBJR@1|root,2Z9N7@2|Bacteria,1TRSN@1239|Firmicutes,4HCDI@91061|Bacilli,1ZDF7@1386|Bacillus 91061|Bacilli S spore germination gerKC - - ko:K06297 - - - - ko00000 - - - Spore_GerAC HPHIIJEP_01598 224308.BSU03700 0.0 979.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerKA - - ko:K06295,ko:K06307 - - - - ko00000 - - - GerA HPHIIJEP_01600 224308.BSU03680 0.0 1057.0 COG5434@1|root,COG5434@2|Bacteria,1V161@1239|Firmicutes,4HUBB@91061|Bacilli,1ZDR3@1386|Bacillus 91061|Bacilli M Pectate lyase superfamily protein yclG - - - - - - - - - - - Beta_helix,Pectate_lyase_3 HPHIIJEP_01601 224308.BSU03670 0.0 932.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,1ZAVZ@1386|Bacillus 91061|Bacilli E amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 HPHIIJEP_01602 224308.BSU03660 5.5e-202 559.0 COG0596@1|root,COG0596@2|Bacteria,1UZ0T@1239|Firmicutes,4HBH8@91061|Bacilli 91061|Bacilli S Alpha beta hydrolase yclE GO:0003674,GO:0003824,GO:0016787 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 HPHIIJEP_01603 224308.BSU03652 1.45e-107 310.0 2DAI9@1|root,32TVI@2|Bacteria,1VD47@1239|Firmicutes,4HKCX@91061|Bacilli,1ZIAY@1386|Bacillus 91061|Bacilli - - yclD - - - - - - - - - - - Putative_PNPOx HPHIIJEP_01604 224308.BSU03651 9.86e-53 165.0 2CK9M@1|root,32SBW@2|Bacteria,1VM7H@1239|Firmicutes,4HY8Z@91061|Bacilli,1ZJD7@1386|Bacillus 91061|Bacilli S response to toxic substance - - 4.1.1.61 ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 - R01238 RC00391 ko00000,ko00001,ko01000 - - - - HPHIIJEP_01605 224308.BSU03640 0.0 972.0 COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,4HM1D@91061|Bacilli,1ZR0K@1386|Bacillus 91061|Bacilli H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate yclC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 M00117 R01238,R04985,R04986,R10213 RC00391,RC03086 ko00000,ko00001,ko00002,ko01000 - - - UbiD HPHIIJEP_01606 224308.BSU03630 2.24e-140 397.0 COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,1ZFID@1386|Bacillus 91061|Bacilli H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein HPHIIJEP_01607 224308.BSU03620 5.32e-209 577.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,1ZFHD@1386|Bacillus 91061|Bacilli K LysR substrate binding domain yclA GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - ko:K21755 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_01608 224308.BSU03610 3.54e-187 520.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,1ZCH3@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 HPHIIJEP_01609 224308.BSU03600 4.6e-157 441.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,1ZBG5@1386|Bacillus 91061|Bacilli P COG0765 ABC-type amino acid transport system, permease component tcyB GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - iYO844.BSU03600 BPD_transp_1 HPHIIJEP_01610 224308.BSU03590 7.11e-172 480.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component tcyC - - ko:K10010 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.14 - iSB619.SA_RS12615 ABC_tran HPHIIJEP_01611 224308.BSU03580 8.71e-148 416.0 COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,4HGYQ@91061|Bacilli,1ZG36@1386|Bacillus 91061|Bacilli S membrane yczE GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1900190,GO:1900192,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K07149 - - - - ko00000 - - - YitT_membrane HPHIIJEP_01612 1051501.AYTL01000031_gene1528 2.02e-146 414.0 COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,4HIVV@91061|Bacilli,1ZHU1@1386|Bacillus 91061|Bacilli H Belongs to the P-Pant transferase superfamily sfp - - ko:K06133 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS HPHIIJEP_01613 224308.BSU03560 0.0 870.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HBNK@91061|Bacilli,1ZCK8@1386|Bacillus 91061|Bacilli K GntR family transcriptional regulator ycxD - - - - - - - - - - - Aminotran_1_2,GntR HPHIIJEP_01614 224308.BSU03550 1.89e-204 568.0 COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes,4HE6N@91061|Bacilli,1ZBXE@1386|Bacillus 91061|Bacilli EG EamA-like transporter family ycxC - - - - - - - - - - - EamA HPHIIJEP_01615 224308.BSU03540 1.48e-122 350.0 2E30Y@1|root,32Y1E@2|Bacteria,1VF3X@1239|Firmicutes,4HNVI@91061|Bacilli,1ZKJM@1386|Bacillus 91061|Bacilli S YcxB-like protein - - - - - - - - - - - - YcxB HPHIIJEP_01616 224308.BSU03530 1.79e-287 786.0 COG0477@1|root,COG2814@2|Bacteria,1UIY9@1239|Firmicutes,4HZ4P@91061|Bacilli,1ZS7C@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_01617 224308.BSU03520 2.71e-178 496.0 COG3208@1|root,COG3208@2|Bacteria,1V3KR@1239|Firmicutes,4HIG8@91061|Bacilli,1ZEUW@1386|Bacillus 91061|Bacilli Q thioesterase srfAD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901576 - ko:K15657 ko02024,map02024 - - - ko00000,ko00001,ko01008 - - - Thioesterase HPHIIJEP_01618 224308.BSU03510 0.0 2498.0 COG1020@1|root,COG1020@2|Bacteria,1VRPH@1239|Firmicutes,4HT9K@91061|Bacilli,1ZREH@1386|Bacillus 91061|Bacilli Q COG1020 Non-ribosomal peptide synthetase modules and related proteins srfAC - - ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase HPHIIJEP_01619 224308.BSU03490 0.0 6955.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall srfAB - - ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_01620 224308.BSU03480 0.0 6988.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall srfAA - - ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding HPHIIJEP_01621 224308.BSU03470 6.05e-86 252.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZH1P@1386|Bacillus 91061|Bacilli K transcriptional hxlR - - - - - - - - - - - HxlR HPHIIJEP_01622 224308.BSU03460 3.97e-137 389.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,1ZBDI@1386|Bacillus 91061|Bacilli G 3-hexulose-6-phosphate synthase hxlA GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase HPHIIJEP_01623 224308.BSU03450 1.54e-124 355.0 COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,4IQVK@91061|Bacilli,1ZRNW@1386|Bacillus 91061|Bacilli G SIS domain hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS HPHIIJEP_01624 224308.BSU03440 8.79e-255 717.0 COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein tlpC - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,sCache_3_3 HPHIIJEP_01625 224308.BSU03430 7.94e-100 290.0 COG3209@1|root,COG3209@2|Bacteria,1V89J@1239|Firmicutes,4HJVE@91061|Bacilli,1ZG0N@1386|Bacillus 91061|Bacilli M Deoxyribonuclease NucA/NucB nucA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DNase_NucA_NucB,Excalibur HPHIIJEP_01626 224308.BSU03420 5.81e-92 268.0 295FN@1|root,2ZSTE@2|Bacteria,1W3MU@1239|Firmicutes,4I00N@91061|Bacilli,1ZJNH@1386|Bacillus 91061|Bacilli S Competence protein J (ComJ) nin GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - ComJ HPHIIJEP_01627 224308.BSU03410 0.0 1007.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,1ZBF2@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family yckE GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.86 ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 HPHIIJEP_01628 1051501.AYTL01000034_gene3344 1.16e-154 436.0 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,1ZCVC@1386|Bacillus 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_15,AAA_21,AAA_23 HPHIIJEP_01629 272558.10173258 9e-32 115.0 2AST8@1|root,31I8D@2|Bacteria,1V7YM@1239|Firmicutes,4HIFG@91061|Bacilli,1ZJ1U@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF3147 HPHIIJEP_01630 720555.BATR1942_20370 7.43e-58 183.0 COG1846@1|root,COG1846@2|Bacteria,1V4JF@1239|Firmicutes,4HHGM@91061|Bacilli,1ZRRE@1386|Bacillus 91061|Bacilli K MarR family - - - - - - - - - - - - HTH_27,MarR HPHIIJEP_01631 224308.BSU03400 9.74e-67 203.0 28P1F@1|root,2ZBXS@2|Bacteria,1V1PR@1239|Firmicutes,4IAIX@91061|Bacilli,1ZIVA@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2680) yckD - - - - - - - - - - - DUF2680 HPHIIJEP_01632 224308.BSU03390 6.42e-96 280.0 COG1714@1|root,COG1714@2|Bacteria,1V6N5@1239|Firmicutes,4HJRB@91061|Bacilli,1ZI28@1386|Bacillus 91061|Bacilli S membrane yckC - - - - - - - - - - - RDD HPHIIJEP_01634 224308.BSU03380 2.17e-186 520.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli,1ZDH6@1386|Bacillus 91061|Bacilli ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 HPHIIJEP_01635 224308.BSU03370 2.99e-149 421.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli,1ZQ0X@1386|Bacillus 91061|Bacilli P COG0765 ABC-type amino acid transport system, permease component yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 HPHIIJEP_01636 224308.BSU03360 2.65e-288 787.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,4HARN@91061|Bacilli,1ZCV4@1386|Bacillus 91061|Bacilli S GTPases (G3E family) yciC - - - - - - - - - - - CobW_C,cobW HPHIIJEP_01637 224308.BSU03350 1.22e-139 394.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli 91061|Bacilli M ErfK YbiS YcfS YnhG - - - - - - - - - - - - YkuD HPHIIJEP_01638 224308.BSU03340 2.03e-220 607.0 COG1469@1|root,COG1469@2|Bacteria,1TTA1@1239|Firmicutes,4H9P4@91061|Bacilli,1ZBW2@1386|Bacillus 91061|Bacilli S Converts GTP to 7,8-dihydroneopterin triphosphate folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 HPHIIJEP_01639 224308.BSU03330 1.3e-281 770.0 COG2223@1|root,COG2223@2|Bacteria,1TRS9@1239|Firmicutes,4HCY1@91061|Bacilli,1ZBQH@1386|Bacillus 91061|Bacilli P COG2223 Nitrate nitrite transporter nasA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - iYO844.BSU03330 MFS_1 HPHIIJEP_01640 224308.BSU03320 0.0 1526.0 COG1251@1|root,COG1251@2|Bacteria,1UIY8@1239|Firmicutes,4ISWS@91061|Bacilli,1ZS7B@1386|Bacillus 91061|Bacilli C Assimilatory nitrate reductase (electron transfer subunit) nasB - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 HPHIIJEP_01641 224308.BSU03310 0.0 1402.0 COG0243@1|root,COG0243@2|Bacteria,1VTS0@1239|Firmicutes,4HAZ4@91061|Bacilli,1ZBMY@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family nasC - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding HPHIIJEP_01642 224308.BSU03300 0.0 1587.0 COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,4HASM@91061|Bacilli,1ZQ9P@1386|Bacillus 91061|Bacilli C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family nasD - 1.7.1.15 ko:K00362 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2 HPHIIJEP_01643 224308.BSU03290 1.2e-74 223.0 COG2146@1|root,COG2146@2|Bacteria,1VBNU@1239|Firmicutes,4HKDI@91061|Bacilli,1ZI6A@1386|Bacillus 91061|Bacilli P Nitrite reductase nasE - 1.7.1.15 ko:K00363 ko00910,ko01120,map00910,map01120 M00530 R00787 RC00176 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03290 Rieske,Rieske_2 HPHIIJEP_01644 224308.BSU03280 0.0 937.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4HBB7@91061|Bacilli,1ZBV1@1386|Bacillus 91061|Bacilli H Belongs to the precorrin methyltransferase family nasF GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.2.1.75 ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase HPHIIJEP_01645 224308.BSU03270 5.52e-241 662.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4HACJ@91061|Bacilli,1ZB05@1386|Bacillus 91061|Bacilli C Ferredoxin--NADP reductase ycgT GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_3 HPHIIJEP_01646 224308.BSU03260 4.02e-201 557.0 COG2267@1|root,COG2267@2|Bacteria,1TUXD@1239|Firmicutes,4HE1R@91061|Bacilli,1ZEWP@1386|Bacillus 91061|Bacilli I alpha/beta hydrolase fold ycgS - - - - - - - - - - - Abhydrolase_1 HPHIIJEP_01647 224308.BSU03250 3.19e-187 523.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli,1ZC03@1386|Bacillus 91061|Bacilli S permeases ycgR - - ko:K07089 - - - - ko00000 - - - ArsP_1 HPHIIJEP_01648 224308.BSU03240 3.01e-192 535.0 COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HG9F@91061|Bacilli,1ZAQN@1386|Bacillus 91061|Bacilli S membrane ycgQ - - ko:K08986 - - - - ko00000 - - - DUF1980 HPHIIJEP_01649 720555.BATR1942_20275 2.73e-130 372.0 COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,4HI0Q@91061|Bacilli,1ZGVP@1386|Bacillus 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01650 720555.BATR1942_20270 0.0 1214.0 COG4652@1|root,COG4652@2|Bacteria,1UZDF@1239|Firmicutes,4IDZU@91061|Bacilli,1ZETS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1430) - - - - - - - - - - - - DUF1430 HPHIIJEP_01652 224308.BSU03230 1.21e-286 784.0 COG2508@1|root,COG2508@2|Bacteria,1UYDU@1239|Firmicutes,4HFGP@91061|Bacilli,1ZQ0M@1386|Bacillus 91061|Bacilli QT COG2508 Regulator of polyketide synthase expression ycgP - - - - - - - - - - - HTH_30 HPHIIJEP_01653 224308.BSU03220 2.64e-316 863.0 COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli,1ZB64@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family putP - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF HPHIIJEP_01654 224308.BSU03210 0.0 1009.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family. RocA subfamily rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - iYO844.BSU37780 Aldedh HPHIIJEP_01655 224308.BSU03200 2.1e-217 600.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase ycgM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh HPHIIJEP_01656 224308.BSU03190 7.76e-187 519.0 COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,4HD38@91061|Bacilli,1ZBMK@1386|Bacillus 91061|Bacilli S Predicted nucleotidyltransferase ycgL - - ko:K07074 - - - - ko00000 - - - Nuc-transf HPHIIJEP_01657 224308.BSU03180 2.59e-230 634.0 COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,4HD1F@91061|Bacilli,1ZQXB@1386|Bacillus 91061|Bacilli Q Acetyl xylan esterase (AXE1) cah - 3.1.1.41 ko:K01060 ko00311,ko01130,map00311,map01130 - R03062 RC00020,RC00041 ko00000,ko00001,ko01000 - - - AXE1 HPHIIJEP_01658 224308.BSU03170 9.34e-227 625.0 COG0583@1|root,COG0583@2|Bacteria,1UZ63@1239|Firmicutes,4HDFA@91061|Bacilli,1ZFCM@1386|Bacillus 91061|Bacilli K LysR substrate binding domain ycgK - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_01659 224308.BSU03160 7.18e-184 511.0 COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HB38@91061|Bacilli,1ZCA4@1386|Bacillus 91061|Bacilli Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 HPHIIJEP_01660 224308.BSU03150 1.05e-136 386.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli,1ZHX4@1386|Bacillus 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI HPHIIJEP_01662 224308.BSU03140 5.99e-137 387.0 COG1660@1|root,COG1660@2|Bacteria,1V1TY@1239|Firmicutes,4HIVE@91061|Bacilli,1ZHR7@1386|Bacillus 91061|Bacilli S AAA domain tmrB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - AAA_18 HPHIIJEP_01663 224308.BSU03130 1.83e-191 531.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,1ZBM2@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0000003,GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019954,GO:0030436,GO:0032502,GO:0034641,GO:0034654,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase HPHIIJEP_01664 224308.BSU03120 7.6e-145 407.0 COG3665@1|root,COG3665@2|Bacteria,1V1VR@1239|Firmicutes,4HVM7@91061|Bacilli,1ZQJI@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1989) ycgI - - ko:K09967 - - - - ko00000 - - - DUF1989 HPHIIJEP_01665 224308.BSU03110 0.0 865.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZDGG@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ycgH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease HPHIIJEP_01666 224308.BSU03100 4.36e-194 536.0 COG3403@1|root,COG3403@2|Bacteria,1US5K@1239|Firmicutes,4HDGW@91061|Bacilli,1ZQUM@1386|Bacillus 91061|Bacilli S YqcI/YcgG family yqcI - - ko:K09190 - - - - ko00000 - - - YqcI_YcgG HPHIIJEP_01667 224308.BSU03090 6.42e-147 414.0 COG1280@1|root,COG1280@2|Bacteria,1V1Q5@1239|Firmicutes,4HFVQ@91061|Bacilli,1ZEMW@1386|Bacillus 91061|Bacilli E Lysine exporter protein LysE YggA ycgF GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - - - - - - - - - - LysE HPHIIJEP_01668 224308.BSU03080 3.7e-101 293.0 COG1846@1|root,COG1846@2|Bacteria,1V8TC@1239|Firmicutes,4HK9G@91061|Bacilli,1ZBA1@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ycgE GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_01669 224308.BSU03070 0.0 931.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,1ZAS8@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily mdr GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_01670 224308.BSU03060 0.0 1006.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm HPHIIJEP_01671 224308.BSU03050 2.93e-233 641.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZD2C@1386|Bacillus 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh GO:0003674,GO:0003824,GO:0004457,GO:0004459,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N HPHIIJEP_01672 224308.BSU03040 0.0 1322.0 COG0366@1|root,COG0366@2|Bacteria,1TQSE@1239|Firmicutes,4HEGR@91061|Bacilli 91061|Bacilli G alpha-amylase amyE - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,CBM26,CBM_20,G5 HPHIIJEP_01673 224308.BSU03030 3.86e-105 305.0 291CP@1|root,2ZNZI@2|Bacteria,1W2X5@1239|Firmicutes,4I0H4@91061|Bacilli,1ZK8J@1386|Bacillus 91061|Bacilli - - ycgB - - - - - - - - - - - - HPHIIJEP_01674 224308.BSU03020 0.0 887.0 COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,4H9P7@91061|Bacilli,1ZBC6@1386|Bacillus 91061|Bacilli S Membrane ycgA - - - - - - - - - - - DcuC,Na_H_antiporter HPHIIJEP_01675 224308.BSU03010 5.64e-276 754.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7R@1239|Firmicutes,4HB6M@91061|Bacilli,1ZB9M@1386|Bacillus 91061|Bacilli S amidohydrolase amhX - - ko:K14665 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HPHIIJEP_01676 224308.BSU03000 2.01e-210 581.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,1ZS5A@1386|Bacillus 91061|Bacilli E glycine betaine opuAC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC HPHIIJEP_01677 224308.BSU02990 2.1e-186 520.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,1ZS1Q@1386|Bacillus 91061|Bacilli P glycine betaine opuAB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0008150,GO:0015695,GO:0015696,GO:0015871,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 HPHIIJEP_01678 224308.BSU02980 8.99e-293 800.0 COG0517@1|root,COG4175@1|root,COG0517@2|Bacteria,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,1ZS1P@1386|Bacillus 91061|Bacilli E glycine betaine opuAA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS HPHIIJEP_01679 224308.BSU02970 4.82e-61 187.0 COG0640@1|root,COG0640@2|Bacteria,1UV2N@1239|Firmicutes,4I4FV@91061|Bacilli,1ZP5F@1386|Bacillus 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 HPHIIJEP_01680 224308.BSU02960 4.64e-258 710.0 COG0477@1|root,COG2814@2|Bacteria,1TSS8@1239|Firmicutes,4HF36@91061|Bacilli,1ZMIV@1386|Bacillus 91061|Bacilli EGP Uncharacterised MFS-type transporter YbfB - - - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_01681 224308.BSU02950 2.7e-278 762.0 COG0477@1|root,COG0477@2|Bacteria,1UIFU@1239|Firmicutes,4ISWR@91061|Bacilli,1ZS7A@1386|Bacillus 91061|Bacilli P Uncharacterised MFS-type transporter YbfB yceI GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,MFS_4,Sugar_tr HPHIIJEP_01682 224308.BSU02940 2.96e-245 675.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4HB7G@91061|Bacilli,1ZQEF@1386|Bacillus 91061|Bacilli P Belongs to the TelA family yceH - - - - - - - - - - - TelA HPHIIJEP_01683 224308.BSU02930 0.0 1080.0 2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,4HC71@91061|Bacilli,1ZBR8@1386|Bacillus 91061|Bacilli S Putative component of 'biosynthetic module' yceG - - - - - - - - - - - YceG_bac HPHIIJEP_01684 224308.BSU02920 4.1e-176 491.0 COG0861@1|root,COG0861@2|Bacteria,1UVIJ@1239|Firmicutes,4HEKW@91061|Bacilli,1ZRX6@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF475) yceF - - ko:K05794 - - - - ko00000 - - - TerC HPHIIJEP_01685 224308.BSU02910 4.97e-138 390.0 COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,4HA7H@91061|Bacilli,1ZBCX@1386|Bacillus 91061|Bacilli T proteins involved in stress response, homologs of TerZ and yceE - - ko:K05795 - - - - ko00000 - - - TerD HPHIIJEP_01686 224308.BSU02900 8.9e-137 387.0 COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,4HA7H@91061|Bacilli,1ZB1M@1386|Bacillus 91061|Bacilli T proteins involved in stress response, homologs of TerZ and yceD - - ko:K05795 - - - - ko00000 - - - TerD HPHIIJEP_01687 224308.BSU02890 3.75e-141 398.0 COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,4HBM3@91061|Bacilli,1ZD3Z@1386|Bacillus 91061|Bacilli T proteins involved in stress response, homologs of TerZ and yceC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - TerD HPHIIJEP_01688 224308.BSU02880 3.44e-237 652.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yceB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase HPHIIJEP_01689 224308.BSU02870 1.88e-172 484.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli,1ZB0A@1386|Bacillus 91061|Bacilli P COG1108 ABC-type Mn2 Zn2 transport systems, permease components adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 HPHIIJEP_01690 224308.BSU02860 1.34e-168 470.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,1ZBS5@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' adcC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran HPHIIJEP_01691 224308.BSU02850 1.95e-221 611.0 COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli,1ZC2Z@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA HPHIIJEP_01692 224308.BSU02840 0.0 1186.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C HPHIIJEP_01693 224308.BSU02830 6.85e-180 501.0 COG1028@1|root,COG1028@2|Bacteria,1VTHQ@1239|Firmicutes,4HTXP@91061|Bacilli,1ZQ6B@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 HPHIIJEP_01694 224308.BSU02820 1.16e-247 682.0 COG0457@1|root,COG0457@2|Bacteria,1UBN0@1239|Firmicutes,4IN2J@91061|Bacilli,1ZMNF@1386|Bacillus 91061|Bacilli S Response regulator aspartate phosphatase rapJ - - ko:K06368 - - - - ko00000,ko01000 - - - TPR_12 HPHIIJEP_01695 224308.BSU02810 2.18e-122 348.0 COG1876@1|root,COG1876@2|Bacteria,1V69M@1239|Firmicutes,4HJT3@91061|Bacilli,1ZPVJ@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - - ko:K17733 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M15_4 HPHIIJEP_01696 224308.BSU02800 0.0 897.0 COG1595@1|root,COG1595@2|Bacteria,1VB3P@1239|Firmicutes,4HMZV@91061|Bacilli 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily ycdC - - ko:K03088 - - - - ko00000,ko03021 - - - DUF4901,Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01697 224308.BSU02790 0.0 932.0 COG1595@1|root,COG1595@2|Bacteria,1VB3P@1239|Firmicutes,4HMZV@91061|Bacilli,1ZH8C@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily ycdB - - ko:K03088 - - - - ko00000,ko03021 - - - DUF4901,Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01698 224308.BSU02780 1.35e-241 665.0 2CEN8@1|root,32ESZ@2|Bacteria,1V92B@1239|Firmicutes,4HJUE@91061|Bacilli,1ZFKF@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF5105) ycdA - - - - - - - - - - - DUF4352,DUF5105 HPHIIJEP_01699 224308.BSU02770 1.37e-221 611.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,1ZCES@1386|Bacillus 91061|Bacilli C Aldo keto reductase yccK - - - - - - - - - - - Aldo_ket_red HPHIIJEP_01700 224308.BSU02760 5.39e-255 702.0 COG1668@1|root,COG1668@2|Bacteria,1V8IQ@1239|Firmicutes,4IQWM@91061|Bacilli,1ZRP0@1386|Bacillus 91061|Bacilli CP ABC-2 family transporter protein - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - iYO844.BSU02760 ABC2_membrane_2 HPHIIJEP_01701 224308.BSU02750 2.2e-170 476.0 COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,4ISGA@91061|Bacilli,1ZC0Y@1386|Bacillus 91061|Bacilli CP ATPases associated with a variety of cellular activities natA - 3.6.3.7 ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 M00253,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.115 - iYO844.BSU02750 ABC_tran HPHIIJEP_01702 224308.BSU02740 6.86e-163 456.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HGFK@91061|Bacilli,1ZAPX@1386|Bacillus 91061|Bacilli T LytTr DNA-binding domain natR - - ko:K02477,ko:K11641 ko02020,map02020 M00494 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg HPHIIJEP_01703 224308.BSU02730 1.19e-210 584.0 COG3290@1|root,COG3290@2|Bacteria,1VK8U@1239|Firmicutes,4HR8P@91061|Bacilli,1ZEI5@1386|Bacillus 91061|Bacilli T GHKL domain natK - 2.7.13.3 ko:K11640 ko02020,map02020 M00494 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,SPOB_a HPHIIJEP_01704 224308.BSU02720 2.04e-254 698.0 COG1405@1|root,COG3012@1|root,COG1405@2|Bacteria,COG3012@2|Bacteria,1V8NE@1239|Firmicutes,4HK5V@91061|Bacilli,1ZE7P@1386|Bacillus 91061|Bacilli K SEC-C motif yccF - - ko:K07039 - - - - ko00000 - - - HTH_psq,SEC-C HPHIIJEP_01705 224308.BSU02710 8.72e-78 232.0 COG1714@1|root,COG1714@2|Bacteria 2|Bacteria S RDD family - - - - - - - - - - - - RDD HPHIIJEP_01706 224308.BSU02700 6.64e-146 411.0 COG1075@1|root,COG1075@2|Bacteria,1VVU8@1239|Firmicutes,4HWN0@91061|Bacilli,1ZB57@1386|Bacillus 91061|Bacilli S acetyltransferases and hydrolases with the alpha beta hydrolase fold - GO:0003674,GO:0003824,GO:0004806,GO:0005575,GO:0005576,GO:0016298,GO:0016787,GO:0016788,GO:0052689 3.1.1.3 ko:K01046 ko00561,ko01100,map00561,map01100 M00098 R02250,R02687 RC00020,RC00037,RC00041,RC00094 ko00000,ko00001,ko00002,ko01000 - - - Lipase_2 HPHIIJEP_01707 224308.BSU02690 1.69e-257 707.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,1ZAZT@1386|Bacillus 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB GO:0003674,GO:0003824,GO:0004067,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase HPHIIJEP_01708 224308.BSU02680 6.54e-132 374.0 COG1309@1|root,COG1309@2|Bacteria,1V9W3@1239|Firmicutes,4IPY1@91061|Bacilli,1ZREG@1386|Bacillus 91061|Bacilli K Transcriptional regulator lmrA - - ko:K18939 - M00715 - - ko00000,ko00002,ko03000 - - - TetR_N HPHIIJEP_01709 224308.BSU02670 1.24e-302 830.0 COG0477@1|root,COG0477@2|Bacteria,1UNMW@1239|Firmicutes,4HFCU@91061|Bacilli,1ZS2J@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 HPHIIJEP_01710 224308.BSU02660 2.16e-262 719.0 COG0520@1|root,COG0520@2|Bacteria,1TRDP@1239|Firmicutes,4HBP7@91061|Bacilli,1ZQ2U@1386|Bacillus 91061|Bacilli E Selenocysteine lyase ycbU - - - - - - - - - - - Aminotran_5 HPHIIJEP_01711 224308.BSU02650 5.7e-153 429.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,1ZEI9@1386|Bacillus 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 HPHIIJEP_01712 224308.BSU02640 3.09e-159 447.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli,1ZBYZ@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC HPHIIJEP_01713 224308.BSU02630 3.12e-38 128.0 COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,4HNM7@91061|Bacilli,1ZIUG@1386|Bacillus 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatAD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 HPHIIJEP_01714 224308.BSU02620 0.0 1190.0 COG3540@1|root,COG3540@2|Bacteria,1UZSJ@1239|Firmicutes,4HE16@91061|Bacilli,1ZB15@1386|Bacillus 91061|Bacilli P COG3540 Phosphodiesterase alkaline phosphatase D phoD - 3.1.3.1 ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 M00126 R04620 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PhoD,PhoD_N HPHIIJEP_01715 224308.BSU02610 2.7e-174 486.0 COG2304@1|root,COG2304@2|Bacteria,1UZ85@1239|Firmicutes,4HCUJ@91061|Bacilli,1ZE5Y@1386|Bacillus 91061|Bacilli T vWA found in TerF C terminus ycbR - - - - - - - - - - - TerD,vWA-TerF-like HPHIIJEP_01716 224308.BSU02600 5.22e-102 295.0 COG3773@1|root,COG3773@2|Bacteria,1V3QK@1239|Firmicutes,4HH00@91061|Bacilli,1ZGB9@1386|Bacillus 91061|Bacilli M Cell wall cwlJ - 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2 HPHIIJEP_01717 224308.BSU02590 2.21e-76 229.0 2E4BW@1|root,32Z7G@2|Bacteria,1VH0F@1239|Firmicutes,4HPQD@91061|Bacilli,1ZJ7Q@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2512) ycbP - - - - - - - - - - - DUF2512 HPHIIJEP_01718 224308.BSU02580 2.87e-148 419.0 COG1277@1|root,2Z9TS@2|Bacteria,1TPNJ@1239|Firmicutes,4HGY0@91061|Bacilli,1ZGQ2@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_4 HPHIIJEP_01719 224308.BSU02570 6.47e-214 591.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HC5D@91061|Bacilli,1ZDHR@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_01720 224308.BSU02560 9.21e-216 596.0 COG0642@1|root,COG2205@2|Bacteria,1TPK5@1239|Firmicutes,4HC46@91061|Bacilli,1ZBGU@1386|Bacillus 91061|Bacilli T Histidine kinase ycbM - - - - - - - - - - - HATPase_c,HisKA HPHIIJEP_01721 224308.BSU02550 1.84e-160 449.0 COG0745@1|root,COG0745@2|Bacteria,1TRK5@1239|Firmicutes,4HE4N@91061|Bacilli,1ZDIJ@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ycbL - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_01722 224308.BSU02540 3.47e-216 597.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination eamA1 - - - - - - - - - - - EamA HPHIIJEP_01723 224308.BSU02530 8.73e-33 113.0 2CJT0@1|root,2ZS83@2|Bacteria,1W42W@1239|Firmicutes,4HZX8@91061|Bacilli 91061|Bacilli K Tryptophan RNA-binding attenuator protein inhibitory protein rtpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - Anti-TRAP HPHIIJEP_01724 224308.BSU02520 7.94e-221 608.0 COG3173@1|root,COG3173@2|Bacteria,1TPYB@1239|Firmicutes,4HBYQ@91061|Bacilli,1ZDCM@1386|Bacillus 91061|Bacilli S Macrolide 2'-phosphotransferase ycbJ - - ko:K06979 - M00760 - - br01600,ko00000,ko00002,ko01504 - - - APH HPHIIJEP_01725 224308.BSU02510 0.0 1014.0 COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,4HAQZ@91061|Bacilli,1ZB6X@1386|Bacillus 91061|Bacilli G Altronate garD GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0008867,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019577,GO:0019579,GO:0019580,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046392,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.42,4.2.1.7 ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00631 R01540,R05608 RC00543 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU02510 GD_AH_C,SAF HPHIIJEP_01726 224308.BSU02500 7.68e-160 448.0 COG2186@1|root,COG2186@2|Bacteria,1UZ3J@1239|Firmicutes,4HCTE@91061|Bacilli,1ZEQX@1386|Bacillus 91061|Bacilli K FCD ycbG - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR HPHIIJEP_01727 224308.BSU02490 0.0 918.0 COG4948@1|root,COG4948@2|Bacteria,1TUWS@1239|Firmicutes,4HCCY@91061|Bacilli,1ZE3M@1386|Bacillus 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family gudD - 4.2.1.40 ko:K01706 ko00053,ko01100,map00053,map01100 - R02752,R08056 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N HPHIIJEP_01728 224308.BSU02480 0.0 888.0 COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,4HEVA@91061|Bacilli,1ZCX2@1386|Bacillus 91061|Bacilli G COG0477 Permeases of the major facilitator superfamily gudP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03535,ko:K08191 - - - - ko00000,ko02000 2.A.1.14.1,2.A.1.14.2 - iYO844.BSU02480 MFS_1 HPHIIJEP_01729 224308.BSU02470 0.0 946.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively ycbD - - ko:K22187 ko00040,map00040 - R11768 RC00080 ko00000,ko00001,ko01000 - - - Aldedh HPHIIJEP_01730 224308.BSU02460 4.1e-222 612.0 COG0329@1|root,COG0329@2|Bacteria,1UHED@1239|Firmicutes,4HAUA@91061|Bacilli,1ZASZ@1386|Bacillus 91061|Bacilli EM 5-dehydro-4-deoxyglucarate dehydratase activity ycbC - 4.2.1.41 ko:K01707 ko00053,ko01100,map00053,map01100 - R02279 RC00678 ko00000,ko00001,ko01000 - - - DHDPS HPHIIJEP_01731 224308.BSU02450 5.76e-216 597.0 COG0784@1|root,COG0784@2|Bacteria,1UHS3@1239|Firmicutes,4HBYG@91061|Bacilli,1ZBP6@1386|Bacillus 91061|Bacilli T Regulator glnL - - ko:K07719 ko02020,map02020 M00518 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,YcbB HPHIIJEP_01732 224308.BSU02440 2.05e-293 803.0 COG4191@1|root,COG4191@2|Bacteria,1UHS4@1239|Firmicutes,4HCZT@91061|Bacilli,1ZD9G@1386|Bacillus 91061|Bacilli T Histidine kinase glnJ - 2.7.13.3 ko:K07717 ko02020,map02020 M00518 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c HPHIIJEP_01733 224308.BSU02430 1.85e-239 657.0 COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,4H9XA@91061|Bacilli,1ZBXX@1386|Bacillus 91061|Bacilli E Belongs to the glutaminase family glsA GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - iYO844.BSU02430 Glutaminase HPHIIJEP_01734 224308.BSU02420 0.0 885.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter agcS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310,ko:K11626 ko02020,map02020 - - - ko00000,ko00001 2.A.25 - - Na_Ala_symp HPHIIJEP_01735 224308.BSU02410 1.29e-233 642.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,1ZC9Q@1386|Bacillus 91061|Bacilli H homocysteine mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans HPHIIJEP_01736 224308.BSU02400 0.0 909.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus 91061|Bacilli E amino acid ybgF GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iYO844.BSU39390 AA_permease HPHIIJEP_01737 224308.BSU02390 8.08e-260 711.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,1ZBFM@1386|Bacillus 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 HPHIIJEP_01739 224308.BSU02370 2.91e-165 462.0 COG2188@1|root,COG2188@2|Bacteria,1TVMZ@1239|Firmicutes,4H9TD@91061|Bacilli,1ZF1V@1386|Bacillus 91061|Bacilli K UTRA - - - ko:K03710,ko:K10711 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_01740 224308.BSU02360 6.09e-174 485.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZMA5@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU02360,iYO844.BSU35020 Glucosamine_iso HPHIIJEP_01741 224308.BSU02350 0.0 1223.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus 91061|Bacilli G phosphotransferase system ptsG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.199 ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 M00282,M00809 R02631,R02738 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.13,4.A.1.1.14,4.A.1.1.6,4.A.1.1.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_01742 224308.BSU02340 6.04e-273 749.0 COG1301@1|root,COG1301@2|Bacteria,1VQUE@1239|Firmicutes,4HU9Y@91061|Bacilli,1ZE4T@1386|Bacillus 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltP - - ko:K11102 - - - - ko00000,ko02000 2.A.23.1.1,2.A.23.1.2 - - SDF HPHIIJEP_01743 224308.BSU02330 1.16e-244 670.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli,1ZCR7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C HPHIIJEP_01744 224308.BSU02320 1.91e-204 566.0 COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,1ZD9Q@1386|Bacillus 91061|Bacilli K Transcriptional regulator ybfP GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 HPHIIJEP_01745 224308.BSU02310 0.0 869.0 COG2312@1|root,COG2312@2|Bacteria,1V2D8@1239|Firmicutes,4HGGF@91061|Bacilli,1ZESJ@1386|Bacillus 91061|Bacilli S Erythromycin esterase - - - ko:K06880 - - - - ko00000,ko01000,ko01504 - - - Erythro_esteras HPHIIJEP_01746 224308.BSU02300 1.58e-59 183.0 2EN3Y@1|root,33FS1@2|Bacteria,1VQE2@1239|Firmicutes,4HS9F@91061|Bacilli 91061|Bacilli - - ybfN - - - - - - - - - - - - HPHIIJEP_01747 224308.BSU02290 2.06e-188 523.0 COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,4HB6I@91061|Bacilli,1ZAZ4@1386|Bacillus 91061|Bacilli I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase HPHIIJEP_01748 224308.BSU02280 7.07e-112 321.0 COG0586@1|root,COG0586@2|Bacteria,1U42T@1239|Firmicutes,4HJQK@91061|Bacilli,1ZFPN@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein ybfM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - SNARE_assoc HPHIIJEP_01749 224308.BSU02270 2.81e-123 351.0 COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HMYA@91061|Bacilli,1ZFNJ@1386|Bacillus 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf HPHIIJEP_01750 224308.BSU02260 6.22e-211 583.0 COG0596@1|root,COG0596@2|Bacteria,1V0M4@1239|Firmicutes,4HPRJ@91061|Bacilli,1ZHQC@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 HPHIIJEP_01752 224308.BSU02240 4.14e-229 630.0 COG3591@1|root,COG3591@2|Bacteria,1VC6K@1239|Firmicutes,4HKUW@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S1B family mpr GO:0005575,GO:0005576 - - - - - - - - - - CW_binding_1,Trypsin,Trypsin_2 HPHIIJEP_01753 224308.BSU02230 2.09e-267 733.0 COG0027@1|root,COG0027@2|Bacteria,1UI4R@1239|Firmicutes,4HEI0@91061|Bacilli,1ZCNZ@1386|Bacillus 91061|Bacilli F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT - 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp,Epimerase HPHIIJEP_01754 1395513.P343_06975 1.65e-81 276.0 COG5585@1|root,COG5585@2|Bacteria,1V069@1239|Firmicutes,4HD0D@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - ADPrib_exo_Tox,PT-TG HPHIIJEP_01755 1395513.P343_06970 1.15e-186 525.0 COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,4HE5F@91061|Bacilli 91061|Bacilli O ADP-ribosylglycohydrolase draG - - - - - - - - - - - ADP_ribosyl_GH HPHIIJEP_01756 224308.BSU02220 1.23e-186 520.0 COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TPNZ@1239|Firmicutes,4HDP3@91061|Bacilli,1ZDS6@1386|Bacillus 91061|Bacilli K AraC-like ligand binding domain ybfI GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - AraC_binding,HTH_18 HPHIIJEP_01757 224308.BSU02210 1.69e-204 567.0 COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,4HFHC@91061|Bacilli,1ZCN0@1386|Bacillus 91061|Bacilli EG EamA-like transporter family ybfH - - - - - - - - - - - EamA HPHIIJEP_01758 224308.BSU02200 0.0 1431.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,1ZN4E@1386|Bacillus 91061|Bacilli M Domain of unknown function (DUF1906) ybfG - - - - - - - - - - - DUF1906,PG_binding_1 HPHIIJEP_01760 224308.BSU02170 1.52e-283 776.0 COG2271@1|root,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,4HDG8@91061|Bacilli,1ZCIM@1386|Bacillus 91061|Bacilli G COG0477 Permeases of the major facilitator superfamily ybfB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_01761 224308.BSU02160 2.02e-216 597.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1VHDQ@1239|Firmicutes,4HQ0R@91061|Bacilli,1ZF1Z@1386|Bacillus 91061|Bacilli K FR47-like protein ybfA - - - - - - - - - - - Acetyltransf_1,MarR,MarR_2 HPHIIJEP_01762 224308.BSU02150 1.02e-46 150.0 2BF7G@1|root,32900@2|Bacteria,1UBBD@1239|Firmicutes,4IMQB@91061|Bacilli,1ZKKX@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2651) - - - - - - - - - - - - DUF2651 HPHIIJEP_01763 224308.BSU02140 0.0 894.0 COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4HE0X@91061|Bacilli,1ZE0D@1386|Bacillus 91061|Bacilli G -transporter glpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02445 - - - - ko00000,ko02000 2.A.1.4.3 - - MFS_1 HPHIIJEP_01764 224308.BSU02130 4.05e-210 580.0 COG0584@1|root,COG0584@2|Bacteria,1UY23@1239|Firmicutes,4HEAD@91061|Bacilli,1ZCIE@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.3.1,3.1.4.46 ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 M00126 R01030,R01470,R04620 RC00017,RC00425 ko00000,ko00001,ko00002,ko01000 - - - GDPD,PhoD,PhoD_N HPHIIJEP_01765 224308.BSU02120 0.0 1056.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HC13@91061|Bacilli,1ZCG6@1386|Bacillus 91061|Bacilli E amino acid ybeC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 HPHIIJEP_01766 224308.BSU02110 1.11e-54 171.0 2E6UJ@1|root,331E9@2|Bacteria,1VHQQ@1239|Firmicutes,4HPYC@91061|Bacilli,1ZK3H@1386|Bacillus 91061|Bacilli - - ybyB - - - - - - - - - - - - HPHIIJEP_01767 224308.BSU02100 3.8e-314 854.0 COG2124@1|root,COG2124@2|Bacteria,1TP02@1239|Firmicutes,4HAIY@91061|Bacilli,1ZB7N@1386|Bacillus 91061|Bacilli Q Cytochrome P450 cypC - 1.11.2.4 ko:K15629 - - R09740 - ko00000,ko00199,ko01000 - - - p450 HPHIIJEP_01768 224308.BSU02090 4.33e-192 533.0 COG2602@1|root,COG2602@2|Bacteria,1VZ0X@1239|Firmicutes,4HTVD@91061|Bacilli,1ZQP5@1386|Bacillus 91061|Bacilli V beta-lactamase ybxI - 3.5.2.6 ko:K17838 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Transpeptidase HPHIIJEP_01769 224308.BSU02080 1.4e-40 133.0 2E4N3@1|root,32ZGZ@2|Bacteria,1VJY0@1239|Firmicutes,4HPM3@91061|Bacilli,1ZJCF@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5370) ybxH - - - - - - - - - - - DUF5370 HPHIIJEP_01770 224308.BSU02070 5.46e-51 161.0 2C58K@1|root,32Y9K@2|Bacteria,1VESG@1239|Firmicutes,4HQS0@91061|Bacilli,1ZIZ4@1386|Bacillus 91061|Bacilli S Sigma-G-dependent sporulation-specific SASP protein csgA - - - - - - - - - - - CsgA HPHIIJEP_01771 224308.BSU02060 0.0 893.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ybxG - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease HPHIIJEP_01772 224308.BSU02050 3e-272 746.0 28KQP@1|root,2ZA8F@2|Bacteria,1UY56@1239|Firmicutes,4IV8V@91061|Bacilli,1ZFX7@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4885) ybdO - - - - - - - - - - - DUF4885 HPHIIJEP_01773 224308.BSU02040 6.07e-192 534.0 2ET76@1|root,33KR7@2|Bacteria,1VMH7@1239|Firmicutes,4ISWQ@91061|Bacilli,1ZDRK@1386|Bacillus 91061|Bacilli - - ybdN - - - - - - - - - - - - HPHIIJEP_01774 224308.BSU02030 3.4e-179 499.0 COG0515@1|root,COG0515@2|Bacteria,1V0NM@1239|Firmicutes,4IPTS@91061|Bacilli,1ZREF@1386|Bacillus 91061|Bacilli KLT Protein tyrosine kinase ybdM - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase HPHIIJEP_01776 224308.BSU02010 4.61e-218 603.0 COG0642@1|root,COG0642@2|Bacteria,1VQZ2@1239|Firmicutes,4HT7I@91061|Bacilli,1ZQJ2@1386|Bacillus 91061|Bacilli T His Kinase A (phospho-acceptor) domain - - - - - - - - - - - - HATPase_c,HisKA HPHIIJEP_01777 224308.BSU02000 9.8e-158 442.0 COG0745@1|root,COG0745@2|Bacteria,1TRNP@1239|Firmicutes,4HBUV@91061|Bacilli,1ZCWC@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_01778 224308.BSU01990 5.45e-231 636.0 COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli,1ZBQD@1386|Bacillus 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1 HPHIIJEP_01779 1051501.AYTL01000034_gene3190 6e-76 226.0 2EGPH@1|root,33AFM@2|Bacteria,1VPIE@1239|Firmicutes,4IMBB@91061|Bacilli,1ZJQ4@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01780 224308.BSU01890 3.13e-256 705.0 COG0477@1|root,COG2814@2|Bacteria,1TRNU@1239|Firmicutes,4HCSX@91061|Bacilli,1ZCJJ@1386|Bacillus 91061|Bacilli EGP COG2814 Arabinose efflux permease ybcL - - ko:K08164 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1,Sugar_tr HPHIIJEP_01781 1051501.AYTL01000034_gene3188 9.45e-67 202.0 COG0640@1|root,COG0640@2|Bacteria,1V98U@1239|Firmicutes,4HIU9@91061|Bacilli,1ZHRJ@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 HPHIIJEP_01782 224308.BSU01880 3.6e-80 238.0 COG5609@1|root,COG5609@2|Bacteria,1V6YC@1239|Firmicutes,4HIMH@91061|Bacilli,1ZH3T@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2294) ybcI - - - - - - - - - - - DUF2294 HPHIIJEP_01783 224308.BSU01870 1.6e-63 194.0 2BF6D@1|root,328YS@2|Bacteria,1UBA5@1239|Firmicutes,4IMNX@91061|Bacilli,1ZKI1@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_01784 224308.BSU01860 5.47e-118 338.0 COG0288@1|root,COG0288@2|Bacteria,1W0HW@1239|Firmicutes,4HYSF@91061|Bacilli,1ZFYB@1386|Bacillus 91061|Bacilli P carbonic anhydrase ybcF - - - - - - - - - - - - HPHIIJEP_01785 224308.BSU01845 0.0 1743.0 COG3002@1|root,COG3002@2|Bacteria,1UWRU@1239|Firmicutes,4HAMS@91061|Bacilli,1ZCP6@1386|Bacillus 91061|Bacilli S Belongs to the UPF0753 family ybcC - - ko:K09822 - - - - ko00000 - - - DUF2309 HPHIIJEP_01786 224308.BSU01830 0.0 929.0 COG1009@1|root,COG1009@2|Bacteria,1TS72@1239|Firmicutes,4HCW7@91061|Bacilli,1ZCMA@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit ndhF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K05577 ko00190,ko01100,map00190,map01100 M00145 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 - - - Proton_antipo_M,Proton_antipo_N HPHIIJEP_01787 935836.JAEL01000009_gene3803 4.57e-126 362.0 COG0671@1|root,COG0671@2|Bacteria,1UZ1A@1239|Firmicutes,4HDCB@91061|Bacilli,1ZFNG@1386|Bacillus 91061|Bacilli I Bacitracin ABC transporter permease bcrC - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 HPHIIJEP_01788 224308.BSU01780 0.0 1160.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,1ZBI5@1386|Bacillus 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS HPHIIJEP_01789 224308.BSU01770 0.0 868.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,1ZC74@1386|Bacillus 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV HPHIIJEP_01790 224308.BSU01760 4.33e-292 804.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,1ZB2T@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR HPHIIJEP_01791 224308.BSU01750 5.43e-189 525.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,1ZBIU@1386|Bacillus 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N HPHIIJEP_01792 224308.BSU01740 1.3e-150 423.0 COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,1ZE1K@1386|Bacillus 91061|Bacilli K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation rsiW GO:0005575,GO:0016020 - - - - - - - - - - Bactofilin,zf-HC2 HPHIIJEP_01793 224308.BSU01730 1.87e-126 360.0 COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01799 224308.BSU01720 9.88e-100 290.0 COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,4HJH0@91061|Bacilli,1ZGEW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF523) ybbK - - - - - - - - - - - DUF523 HPHIIJEP_01800 224308.BSU01710 3.13e-114 327.0 COG1670@1|root,COG1670@2|Bacteria,1VB0J@1239|Firmicutes,4HMJ9@91061|Bacilli,1ZHYA@1386|Bacillus 91061|Bacilli J acetyltransferase ybbJ - - - - - - - - - - - Acetyltransf_1,Acetyltransf_8 HPHIIJEP_01801 224308.BSU01700 1.58e-208 577.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,1ZCFF@1386|Bacillus 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 HPHIIJEP_01802 224308.BSU01690 5.43e-194 539.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,1ZQ09@1386|Bacillus 91061|Bacilli K transcriptional ybbH GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_6,SIS HPHIIJEP_01803 224308.BSU01680 6.98e-302 826.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4H9KS@91061|Bacilli,1ZE6P@1386|Bacillus 91061|Bacilli G phosphotransferase system ybbF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090588 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_01804 224308.BSU01670 0.0 865.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,1ZBJ0@1386|Bacillus 91061|Bacilli V Belongs to the UPF0214 family ybbE - 3.4.16.4 ko:K21469 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Beta-lactamase HPHIIJEP_01805 224308.BSU01660 0.0 1218.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family ybbD - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Big_2,Glyco_hydro_3,Glyco_hydro_3_C,Gram_pos_anchor,SLH HPHIIJEP_01806 224308.BSU01650 2.33e-302 824.0 COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1ZBF3@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ybbC - - - - - - - - - - - DUF1343 HPHIIJEP_01807 224308.BSU01640 0.0 1023.0 COG0614@1|root,COG2207@1|root,COG0614@2|Bacteria,COG2207@2|Bacteria,1UA6E@1239|Firmicutes,4HE6W@91061|Bacilli,1ZF3U@1386|Bacillus 91061|Bacilli K COG2207 AraC-type DNA-binding domain-containing proteins ybbB - - ko:K21701 - - - - ko00000,ko03000 - - - HTH_18,HTH_AraC,Peripla_BP_2 HPHIIJEP_01808 224308.BSU01630 2.54e-216 598.0 COG0614@1|root,COG0614@2|Bacteria,1TQY2@1239|Firmicutes,4HB4K@91061|Bacilli,1ZEG1@1386|Bacillus 91061|Bacilli P Iron-uptake system-binding protein feuA GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 HPHIIJEP_01809 224308.BSU01620 1.17e-225 623.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HA75@91061|Bacilli,1ZC7Z@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily feuB GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071944 - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_01810 224308.BSU01610 5.82e-227 627.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HD4U@91061|Bacilli,1ZQ8W@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily feuC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_01811 224308.BSU01600 5.24e-180 501.0 COG2819@1|root,COG2819@2|Bacteria,1VAX2@1239|Firmicutes,4HGZQ@91061|Bacilli,1ZFE7@1386|Bacillus 91061|Bacilli S Putative esterase ybbA - - ko:K07017 - - - - ko00000 - - - Esterase HPHIIJEP_01812 1051501.AYTL01000034_gene3161 3.77e-203 565.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HB6E@91061|Bacilli,1ZQNX@1386|Bacillus 91061|Bacilli S Na -dependent transporter ybaS - - - - - - - - - - - SBF,SBF_like HPHIIJEP_01814 224308.BSU01580 0.0 868.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) ybaR - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp HPHIIJEP_01815 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01816 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01823 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01824 224308.BSU01570 8.69e-181 503.0 COG0726@1|root,COG0726@2|Bacteria,1UZQS@1239|Firmicutes,4IPKY@91061|Bacilli,1ZRC8@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase pdaB GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 - - - - - - - - - - Polysacc_deac_1 HPHIIJEP_01825 224308.BSU01560 5.95e-133 377.0 COG2194@1|root,COG2194@2|Bacteria,1UZ64@1239|Firmicutes,4HFDE@91061|Bacilli,1ZFN5@1386|Bacillus 91061|Bacilli S Involved in the activation of the KinB signaling pathway of sporulation kbaA GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K06349 - - - - ko00000 - - - KbaA HPHIIJEP_01826 224308.BSU01550 1.04e-122 350.0 29HQ2@1|root,32TXD@2|Bacteria,1VAW4@1239|Firmicutes,4HMNZ@91061|Bacilli,1ZQMV@1386|Bacillus 91061|Bacilli - - gerD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0031160,GO:0044464,GO:0071944 - ko:K06294 - - - - ko00000 - - - - HPHIIJEP_01827 224308.BSU01540 1.1e-255 701.0 COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4HAW4@91061|Bacilli,1ZC2E@1386|Bacillus 91061|Bacilli D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA HPHIIJEP_01828 224308.BSU01530 9.05e-170 474.0 COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4HAV3@91061|Bacilli,1ZBJ8@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase cwlD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 HPHIIJEP_01829 224308.BSU01520 2.54e-91 268.0 2BVDP@1|root,32QTK@2|Bacteria,1V9E2@1239|Firmicutes,4HJ1S@91061|Bacilli,1ZFUF@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2521) ybaK - - - - - - - - - - - DUF2521 HPHIIJEP_01830 224308.BSU01510 2.06e-184 512.0 COG0500@1|root,COG2226@2|Bacteria,1TR3E@1239|Firmicutes,4HA5G@91061|Bacilli,1ZF9T@1386|Bacillus 91061|Bacilli Q Methyltransferase domain ybaJ - - - - - - - - - - - Methyltransf_11 HPHIIJEP_01831 224308.BSU01500 4.28e-84 248.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,1ZG6R@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 HPHIIJEP_01832 1051501.AYTL01000005_gene368 1.13e-102 296.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,1ZFJA@1386|Bacillus 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 HPHIIJEP_01833 224308.BSU01480 6.15e-182 505.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,1ZCC7@1386|Bacillus 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 HPHIIJEP_01834 224308.BSU01470 1.6e-177 496.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,1ZBNS@1386|Bacillus 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ HPHIIJEP_01835 1051501.AYTL01000005_gene365 3.06e-192 536.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,1ZBBK@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran HPHIIJEP_01836 224308.BSU01450 3.56e-198 549.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,1ZBD2@1386|Bacillus 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran HPHIIJEP_01837 1051501.AYTL01000005_gene363 4.27e-77 230.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,1ZG80@1386|Bacillus 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 HPHIIJEP_01838 224308.BSU01430 7.01e-217 599.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,1ZBHX@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L HPHIIJEP_01839 224308.BSU01420 3.24e-84 249.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1ZFIU@1386|Bacillus 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 HPHIIJEP_01840 224308.BSU01410 1.09e-75 226.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,1ZGAW@1386|Bacillus 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 HPHIIJEP_01841 1178537.BA1_05527 2.45e-19 78.2 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,1ZK67@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 HPHIIJEP_01842 1051501.AYTL01000005_gene359 2.92e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1ZHWN@1386|Bacillus 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a HPHIIJEP_01843 224308.BSU01380 2.32e-182 506.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,1ZBQI@1386|Bacillus 91061|Bacilli E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 HPHIIJEP_01844 224308.BSU01370 2.51e-157 441.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,1ZBYM@1386|Bacillus 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid HPHIIJEP_01845 224308.BSU01360 5.7e-298 814.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,1ZCEG@1386|Bacillus 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY HPHIIJEP_01846 1051501.AYTL01000005_gene355 7.32e-95 277.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,1ZFMY@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A HPHIIJEP_01847 1051501.AYTL01000005_gene354 1.59e-33 115.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,1ZITD@1386|Bacillus 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 HPHIIJEP_01848 326423.RBAM_001580 9.16e-111 319.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,1ZBWE@1386|Bacillus 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C HPHIIJEP_01849 224308.BSU01320 2.89e-75 225.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,1ZG7C@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p HPHIIJEP_01850 224308.BSU01310 4.47e-121 346.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1ZCR5@1386|Bacillus 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 HPHIIJEP_01851 224308.BSU01300 3.11e-87 256.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,1ZFMC@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 HPHIIJEP_01852 224308.BSU01290 1.43e-39 130.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,1ZHVE@1386|Bacillus 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 HPHIIJEP_01853 224308.BSU01280 7.72e-122 348.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,1ZB6T@1386|Bacillus 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C HPHIIJEP_01854 1051501.AYTL01000005_gene347 1.43e-67 204.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,1ZGZQ@1386|Bacillus 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 HPHIIJEP_01855 1051501.AYTL01000005_gene346 3.62e-79 235.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,1ZG7H@1386|Bacillus 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 HPHIIJEP_01856 224308.BSU01250 1.64e-52 165.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,1ZH2Q@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 HPHIIJEP_01857 1051501.AYTL01000005_gene344 1.88e-35 120.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,1ZI7W@1386|Bacillus 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 HPHIIJEP_01858 1051501.AYTL01000005_gene343 1.96e-98 286.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,1ZFMZ@1386|Bacillus 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 HPHIIJEP_01859 224308.BSU01220 5.9e-152 427.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,1ZBA9@1386|Bacillus 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C HPHIIJEP_01860 224308.BSU01210 9.23e-71 213.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,1ZG6U@1386|Bacillus 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 HPHIIJEP_01861 1051501.AYTL01000005_gene340 2.83e-62 190.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,1ZGXY@1386|Bacillus 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 HPHIIJEP_01862 224308.BSU01190 2.72e-200 554.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,1ZCQP@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C HPHIIJEP_01863 224308.BSU01180 3.27e-58 180.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,1ZH09@1386|Bacillus 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 HPHIIJEP_01864 1051501.AYTL01000005_gene337 7.98e-136 385.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,1ZBG9@1386|Bacillus 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 HPHIIJEP_01865 224308.BSU01160 7.2e-144 406.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,1ZCM8@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 HPHIIJEP_01866 1051501.AYTL01000005_gene335 2.58e-65 199.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,1ZGA6@1386|Bacillus 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 HPHIIJEP_01867 224308.BSU01140 5.23e-230 633.0 COG0596@1|root,COG0596@2|Bacteria,1UHTA@1239|Firmicutes,4IS90@91061|Bacilli,1ZS38@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family ybaC - - - - - - - - - - - Hydrolase_4 HPHIIJEP_01868 224308.BSU01130 2.01e-287 785.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - iSB619.SA_RS02960 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 HPHIIJEP_01869 224308.BSU01120 0.0 1360.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,1ZBS4@1386|Bacillus 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 HPHIIJEP_01870 1051501.AYTL01000005_gene331 4.85e-107 308.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,1ZBVR@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 HPHIIJEP_01871 224308.BSU01100 6.67e-94 274.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,1ZFM9@1386|Bacillus 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 HPHIIJEP_01872 224308.BSU01090 1.99e-44 144.0 COG1358@1|root,COG1358@2|Bacteria,1VFD8@1239|Firmicutes,4HNXS@91061|Bacilli,1ZIU6@1386|Bacillus 91061|Bacilli J Belongs to the eukaryotic ribosomal protein eL8 family rplGB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07590 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L7Ae HPHIIJEP_01873 224308.BSU01080 0.0 2362.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,1ZDK0@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 HPHIIJEP_01874 224308.BSU01070 0.0 2354.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,1ZBPC@1386|Bacillus 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 HPHIIJEP_01875 224308.BSU01060 7.25e-140 395.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,1ZBPR@1386|Bacillus 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS HPHIIJEP_01876 1051501.AYTL01000005_gene325 2.84e-64 198.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,1ZG84@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N HPHIIJEP_01877 224308.BSU01040 4.03e-104 302.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,1ZBGK@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 HPHIIJEP_01878 224308.BSU01030 1.82e-162 455.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 HPHIIJEP_01879 224308.BSU01020 3.4e-93 272.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,1ZFIG@1386|Bacillus 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N HPHIIJEP_01880 224308.BSU01010 1.37e-124 355.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,1ZBRH@1386|Bacillus 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG HPHIIJEP_01881 224308.BSU01000 2.65e-32 112.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,1ZIY2@1386|Bacillus 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE HPHIIJEP_01882 224308.BSU00980 3.27e-149 420.0 COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,4HAHR@91061|Bacilli,1ZBEV@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_01883 224308.BSU00970 3.31e-114 328.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,1ZCMG@1386|Bacillus 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP HPHIIJEP_01884 224308.BSU00960 3.52e-173 483.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind HPHIIJEP_01885 224308.BSU00950 2.04e-95 278.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,1ZH0Z@1386|Bacillus 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 HPHIIJEP_01886 224308.BSU00940 0.0 937.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,1ZB69@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g HPHIIJEP_01887 224308.BSU00930 1.91e-152 428.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli,1ZCNM@1386|Bacillus 91061|Bacilli E Serine acetyltransferase cysE GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02865,iYO844.BSU00930 Hexapep,SATase_N HPHIIJEP_01888 224308.BSU00920 0.0 967.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,1ZAWK@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c HPHIIJEP_01889 224308.BSU00910 6.35e-113 323.0 COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,4HG1X@91061|Bacilli,1ZB1U@1386|Bacillus 91061|Bacilli I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB HPHIIJEP_01890 224308.BSU00900 2.13e-161 452.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,1ZCWR@1386|Bacillus 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD HPHIIJEP_01891 224308.BSU00890 2.57e-252 693.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,1ZB5A@1386|Bacillus 91061|Bacilli S COG4956 Integral membrane protein (PIN domain superfamily) yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM HPHIIJEP_01892 224308.BSU00880 3.8e-251 690.0 COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,4HAQP@91061|Bacilli,1ZBIY@1386|Bacillus 91061|Bacilli L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation disA - 2.7.7.85 ko:K07067 - - - - ko00000,ko01000 - - - DisA-linker,DisA_N,HHH,HHH_2 HPHIIJEP_01893 224308.BSU00870 0.0 890.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI HPHIIJEP_01894 224308.BSU00860 0.0 1538.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR HPHIIJEP_01895 224308.BSU00850 7.74e-257 704.0 COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,4HC6U@91061|Bacilli,1ZBJU@1386|Bacillus 91061|Bacilli E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity mcsB GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans HPHIIJEP_01896 1051501.AYTL01000005_gene306 2.36e-74 223.0 COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus 91061|Bacilli S protein with conserved CXXC pairs mcsA GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - ko:K19411 - - - - ko00000 - - - UVR HPHIIJEP_01897 224308.BSU00830 8.72e-100 290.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,1ZFR6@1386|Bacillus 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR HPHIIJEP_01898 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01908 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01909 224308.BSU00820 0.0 989.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,1ZAVI@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon HPHIIJEP_01910 224308.BSU00810 1.59e-243 668.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,1ZC6T@1386|Bacillus 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus HPHIIJEP_01911 224308.BSU00800 1.81e-41 136.0 COG1396@1|root,COG1396@2|Bacteria,1VIT6@1239|Firmicutes,4HP4J@91061|Bacilli,1ZJ4Q@1386|Bacillus 91061|Bacilli K transcriptional yazB - - - - - - - - - - - HTH_3 HPHIIJEP_01912 224308.BSU00790 4.56e-115 330.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK HPHIIJEP_01913 224308.BSU00780 3.8e-80 238.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,1ZGZ7@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB HPHIIJEP_01914 224308.BSU00770 3.88e-204 565.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind HPHIIJEP_01915 224308.BSU00760 5.36e-215 593.0 COG0115@1|root,COG0115@2|Bacteria,1TSIP@1239|Firmicutes,4HC7K@91061|Bacilli,1ZCRC@1386|Bacillus 91061|Bacilli EH 4-amino-4-deoxychorismate lyase pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 HPHIIJEP_01916 224308.BSU00750 1.72e-136 386.0 COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,1ZBB7@1386|Bacillus 91061|Bacilli EH Anthranilate synthase pabA GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01664 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - iYO844.BSU00750 GATase HPHIIJEP_01917 224308.BSU00740 0.0 919.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 ko:K01665 ko00790,map00790 - R01716 RC00010,RC01418 ko00000,ko00001,ko01000 - - - Anth_synt_I_N,Chorismate_bind HPHIIJEP_01918 224308.BSU00730 1.54e-217 600.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZBC7@1386|Bacillus 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP HPHIIJEP_01919 224308.BSU00720 5.26e-193 537.0 COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,1ZBFZ@1386|Bacillus 91061|Bacilli O peptidyl-prolyl isomerase yacD - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 HPHIIJEP_01920 224308.BSU00710 9.54e-208 574.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,1ZBFC@1386|Bacillus 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 HPHIIJEP_01921 224308.BSU00700 8.08e-188 521.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase HPHIIJEP_01922 224308.BSU00690 0.0 1233.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,1ZBEU@1386|Bacillus 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 HPHIIJEP_01923 224308.BSU00680 4.82e-121 346.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,1ZB7B@1386|Bacillus 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 - - - Pribosyltran HPHIIJEP_01924 224308.BSU00670 0.0 936.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,1ZBFQ@1386|Bacillus 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C HPHIIJEP_01925 224308.BSU00660 1.2e-236 651.0 COG0515@1|root,COG0515@2|Bacteria,1TSNS@1239|Firmicutes,4HBDI@91061|Bacilli,1ZBVA@1386|Bacillus 91061|Bacilli KLT serine threonine protein kinase yabT - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase HPHIIJEP_01926 224308.BSU00650 5.61e-168 470.0 COG2304@1|root,COG2304@2|Bacteria,1U1SJ@1239|Firmicutes,4HD70@91061|Bacilli,1ZC1N@1386|Bacillus 91061|Bacilli S protein containing a von Willebrand factor type A (vWA) domain yabS - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 HPHIIJEP_01927 224308.BSU00640 0.0 1550.0 COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,4HB0X@91061|Bacilli,1ZAYZ@1386|Bacillus 91061|Bacilli KT stage II sporulation protein E spoIIE GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 3.1.3.16 ko:K06382 - - - - ko00000,ko01000 - - - SpoIIE HPHIIJEP_01930 1051501.AYTL01000009_gene201 2.49e-82 244.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,1ZG7S@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yabR - - ko:K07571 - - - - ko00000 - - - S1 HPHIIJEP_01931 224308.BSU00620 4.18e-75 225.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli,1ZIBZ@1386|Bacillus 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC HPHIIJEP_01932 224308.BSU00610 1.49e-137 390.0 2BYDV@1|root,32RAH@2|Bacteria,1V91M@1239|Firmicutes,4HIIQ@91061|Bacilli,1ZH7H@1386|Bacillus 91061|Bacilli S spore cortex biosynthesis protein yabQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - Spore_YabQ HPHIIJEP_01933 224308.BSU00600 1.91e-66 201.0 2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,4HPDE@91061|Bacilli,1ZGYU@1386|Bacillus 91061|Bacilli S Sporulation protein YabP yabP GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - YabP HPHIIJEP_01934 224308.BSU00590 4.22e-50 159.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,1ZHXN@1386|Bacillus 91061|Bacilli J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 HPHIIJEP_01935 224308.BSU00580 0.0 882.0 COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1ZAYB@1386|Bacillus 91061|Bacilli S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like yabN GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG,TP_methylase HPHIIJEP_01936 224308.BSU00570 0.0 976.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,1ZBBF@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C HPHIIJEP_01937 224308.BSU00560 5.88e-121 345.0 COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,4HDIW@91061|Bacilli,1ZAXU@1386|Bacillus 91061|Bacilli K stage V sporulation protein spoVT GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04769 - - - - ko00000,ko03000 - - - MazE_antitoxin,SpoVT_C HPHIIJEP_01938 224308.BSU00550 0.0 2248.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,1ZBAK@1386|Bacillus 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF HPHIIJEP_01939 224308.BSU00540 6.36e-54 168.0 2EJ4H@1|root,33CVR@2|Bacteria,1VMIU@1239|Firmicutes,4HP24@91061|Bacilli,1ZJ5B@1386|Bacillus 91061|Bacilli S Peptide ABC transporter permease yabK - - - - - - - - - - - DUF2757 HPHIIJEP_01940 224308.BSU00530 2.03e-135 383.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro HPHIIJEP_01941 224308.BSU00520 4.79e-126 360.0 COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,1ZDPJ@1386|Bacillus 91061|Bacilli J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C HPHIIJEP_01942 224308.BSU00510 1.22e-223 617.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,1ZD4C@1386|Bacillus 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N HPHIIJEP_01943 224308.BSU00500 2.58e-309 845.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase HPHIIJEP_01944 720555.BATR1942_18855 2.45e-63 193.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,1ZGXK@1386|Bacillus 91061|Bacilli D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation spoVG GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - ko:K06412 - - - - ko00000 - - - SpoVG HPHIIJEP_01945 1051501.AYTL01000009_gene187 3.45e-83 246.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,1ZG9Q@1386|Bacillus 91061|Bacilli J translation initiation inhibitor, yjgF family yabJ GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046360,GO:0046361,GO:0046394,GO:0046459,GO:0051790,GO:0071704,GO:0072330,GO:1901576 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP HPHIIJEP_01946 224308.BSU00470 4.66e-196 544.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,1ZAW9@1386|Bacillus 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N HPHIIJEP_01947 224308.BSU00460 2.34e-207 573.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,1ZAYT@1386|Bacillus 91061|Bacilli I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N HPHIIJEP_01948 224308.BSU00440 5.32e-53 166.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,1ZI19@1386|Bacillus 91061|Bacilli S protein conserved in bacteria veg - - - - - - - - - - - VEG HPHIIJEP_01949 224308.BSU00430 1.11e-198 551.0 28HCB@1|root,2Z7P7@2|Bacteria,1TNZK@1239|Firmicutes,4HBET@91061|Bacilli,1ZCTC@1386|Bacillus 91061|Bacilli S peptidase yabG GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0031160,GO:0043591,GO:0043593,GO:0044426,GO:0044462,GO:0044464,GO:0071944 - ko:K06436 - - - - ko00000 - - - Peptidase_U57 HPHIIJEP_01950 224308.BSU00420 2.91e-198 550.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,1ZBZX@1386|Bacillus 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD HPHIIJEP_01951 224308.BSU00410 2.03e-125 357.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 HPHIIJEP_01952 224308.BSU00400 4.1e-278 764.0 COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4HC79@91061|Bacilli,1ZC0Q@1386|Bacillus 91061|Bacilli T protein conserved in bacteria yabE - - - - - - - - - - - 3D,DUF348,G5 HPHIIJEP_01953 224308.BSU00390 5.9e-184 511.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,1ZB78@1386|Bacillus 91061|Bacilli L hydrolase, TatD tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase HPHIIJEP_01954 224308.BSU00380 0.0 1325.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,1ZASP@1386|Bacillus 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind HPHIIJEP_01955 1051501.AYTL01000009_gene176 1.51e-58 181.0 COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,4HKCH@91061|Bacilli,1ZH0F@1386|Bacillus 91061|Bacilli K COG2002 Regulators of stationary sporulation gene expression abrB GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K06284 - - - - ko00000,ko03000 - - - MazE_antitoxin HPHIIJEP_01956 224308.BSU00360 1.2e-206 572.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,1ZBN1@1386|Bacillus 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase HPHIIJEP_01957 224308.BSU00350 1.2e-64 197.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,1ZIXI@1386|Bacillus 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG HPHIIJEP_01958 224308.BSU00340 1.63e-177 494.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,1ZCBX@1386|Bacillus 91061|Bacilli S Conserved hypothetical protein 95 yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS HPHIIJEP_01959 224308.BSU00330 1.53e-56 178.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,1ZGZH@1386|Bacillus 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB HPHIIJEP_01960 224308.BSU00320 6.33e-189 525.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli,1ZBCK@1386|Bacillus 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 HPHIIJEP_01961 224308.BSU00310 2.82e-235 647.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,1ZBDA@1386|Bacillus 91061|Bacilli L DNA polymerase III holB GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C HPHIIJEP_01962 224308.BSU00300 1.26e-95 279.0 COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,4HP8D@91061|Bacilli,1ZFYU@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yaaR - - ko:K09770 - - - - ko00000 - - - DUF327 HPHIIJEP_01963 224308.BSU00290 1.02e-72 218.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,1ZHEA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yaaQ - - - - - - - - - - - CdAMP_rec HPHIIJEP_01964 224308.BSU00280 1.63e-146 413.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,1ZBSZ@1386|Bacillus 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin HPHIIJEP_01965 224308.BSU00270 0.0 939.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus 91061|Bacilli E Orn Lys Arg decarboxylase yaaO - - - - - - - - - - - OKR_DC_1,OKR_DC_1_C HPHIIJEP_01966 224308.BSU00260 1.02e-259 714.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,1ZATR@1386|Bacillus 91061|Bacilli P Belongs to the TelA family yaaN - - - - - - - - - - - TelA HPHIIJEP_01967 224308.BSU00250 3.28e-133 379.0 COG4915@1|root,COG4915@2|Bacteria,1V5B1@1239|Firmicutes,4HKAX@91061|Bacilli,1ZG4A@1386|Bacillus 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein xpaC - - - - - - - - - - - Halogen_Hydrol HPHIIJEP_01968 224308.BSU00240 2.21e-42 138.0 2EIS2@1|root,33CHE@2|Bacteria,1VM34@1239|Firmicutes,4HR6Z@91061|Bacilli,1ZK09@1386|Bacillus 91061|Bacilli S Inhibitor of sigma-G Gin csfB - - - - - - - - - - - Gin HPHIIJEP_01971 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01972 224308.BSU00230 5.3e-49 156.0 2E9CH@1|root,333K6@2|Bacteria,1VG2H@1239|Firmicutes,4HNZC@91061|Bacilli,1ZIUF@1386|Bacillus 91061|Bacilli S Sigma-K factor-processing regulatory protein BofA bofA - - ko:K06317 - - - - ko00000 - - - BofA HPHIIJEP_01973 224308.BSU00220 1.55e-42 139.0 2EHEM@1|root,33B6J@2|Bacteria,1VM3Z@1239|Firmicutes,4HR3I@91061|Bacilli,1ZIUR@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2508) yaaL - - - - - - - - - - - DUF2508 HPHIIJEP_01974 224308.BSU00210 8.53e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 HPHIIJEP_01975 224308.BSU00200 8.75e-55 172.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,1ZGZI@1386|Bacillus 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd HPHIIJEP_01976 224308.BSU00190 0.0 1093.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,1ZB2M@1386|Bacillus 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 HPHIIJEP_01977 224308.BSU00180 3e-108 312.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,1ZFRP@1386|Bacillus 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam HPHIIJEP_01978 224308.BSU00170 5.64e-125 356.0 COG1335@1|root,COG1335@2|Bacteria,1V5Y9@1239|Firmicutes,4HHKW@91061|Bacilli,1ZQ73@1386|Bacillus 91061|Bacilli Q COG1335 Amidases related to nicotinamidase yaaI GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - - - - - - - - - - Isochorismatase HPHIIJEP_01979 224308.BSU00160 5.18e-276 758.0 COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,4HBJC@91061|Bacilli,1ZBQC@1386|Bacillus 91061|Bacilli M Glycoside Hydrolase Family yaaH - - ko:K06306 - - - - ko00000 - - - Glyco_hydro_18,LysM HPHIIJEP_01980 224308.BSU00150 5.73e-149 419.0 COG1428@1|root,COG1428@2|Bacteria,1TQKS@1239|Firmicutes,4HBWC@91061|Bacilli,1ZCAQ@1386|Bacillus 91061|Bacilli F Deoxyguanosine kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK HPHIIJEP_01981 224308.BSU00140 2.15e-158 443.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,1ZBFB@1386|Bacillus 91061|Bacilli F Deoxycytidine kinase dck - 2.7.1.74,2.7.1.76 ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 - R00185,R01666,R02089 RC00002,RC00017 ko00000,ko00001,ko01000 - - - dNK HPHIIJEP_01983 224308.BSU00130 5.66e-295 806.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1ZCBQ@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b HPHIIJEP_01984 224308.BSU00120 1.66e-138 391.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,1ZD5C@1386|Bacillus 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO HPHIIJEP_01985 224308.BSU00110 3.7e-202 560.0 COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli,1ZB36@1386|Bacillus 91061|Bacilli H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ HPHIIJEP_01986 224308.BSU00100 3.75e-316 861.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,1ZAS6@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 HPHIIJEP_01987 224308.BSU00090 0.0 946.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,1ZC91@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH HPHIIJEP_01988 224308.BSU00080 6.14e-232 637.0 28JUG@1|root,2Z9JI@2|Bacteria,1UYYT@1239|Firmicutes,4HC3E@91061|Bacilli,1ZBYK@1386|Bacillus 91061|Bacilli S YaaC-like Protein yaaC - - - - - - - - - - - YaaC HPHIIJEP_01991 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_01992 224308.BSU00070 0.0 1439.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,1ZB8F@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV HPHIIJEP_01993 224308.BSU00060 0.0 1258.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,1ZBFI@1386|Bacillus 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim HPHIIJEP_01994 224308.BSU00050 1.25e-51 162.0 2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,4HQTK@91061|Bacilli,1ZIZ5@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF370) yaaB - - - - - - - - - - - DUF370 HPHIIJEP_01995 224308.BSU00040 1.85e-263 722.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,1ZC8V@1386|Bacillus 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N HPHIIJEP_01996 224308.BSU00030 2.24e-45 146.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,1ZIXZ@1386|Bacillus 91061|Bacilli S S4 domain yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 HPHIIJEP_01997 224308.BSU00020 9.88e-263 721.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,1ZAVV@1386|Bacillus 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_3 HPHIIJEP_01998 224308.BSU00010 0.0 877.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N HPHIIJEP_01999 224308.BSU41050 5.7e-71 214.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,1ZHUH@1386|Bacillus 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P HPHIIJEP_02000 224308.BSU41040 9.29e-179 498.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,1ZBYD@1386|Bacillus 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP HPHIIJEP_02001 224308.BSU41030 1.06e-140 398.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,1ZDGU@1386|Bacillus 91061|Bacilli S single-stranded nucleic acid binding R3H jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H HPHIIJEP_02002 224308.BSU41020 0.0 868.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,1ZBTZ@1386|Bacillus 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N HPHIIJEP_02003 224308.BSU41010 0.0 1226.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,1ZB67@1386|Bacillus 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc HPHIIJEP_02004 224308.BSU41000 1.01e-167 469.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,1ZAWG@1386|Bacillus 91061|Bacilli J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB HPHIIJEP_02005 224308.BSU40990 9e-193 536.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,1ZCDV@1386|Bacillus 91061|Bacilli D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc HPHIIJEP_02006 224308.BSU40980 1.13e-98 286.0 2DZPD@1|root,32VFE@2|Bacteria,1VAZH@1239|Firmicutes,4HMUD@91061|Bacilli,1ZIQ3@1386|Bacillus 91061|Bacilli S Bacterial PH domain - - - - - - - - - - - - bPH_4 HPHIIJEP_02007 224308.BSU40970 4.79e-173 483.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus 91061|Bacilli D COG1192 ATPases involved in chromosome partitioning soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 HPHIIJEP_02008 224308.BSU40960 3.96e-191 531.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,1ZBDT@1386|Bacillus 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc HPHIIJEP_02009 224308.BSU40950 9.15e-145 408.0 2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,4HH5B@91061|Bacilli,1ZCER@1386|Bacillus 91061|Bacilli S Sporulation protein YyaC yyaC - - - - - - - - - - - DUF1256 HPHIIJEP_02010 224308.BSU40940 6.23e-226 624.0 COG3949@1|root,COG3949@2|Bacteria,1U1WV@1239|Firmicutes,4H9MI@91061|Bacilli,1ZQME@1386|Bacillus 91061|Bacilli S Membrane yyaD - - - - - - - - - - - - HPHIIJEP_02011 224308.BSU40939 7.41e-45 144.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,1ZIUV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 HPHIIJEP_02012 224308.BSU40930 0.0 1335.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HTGY@91061|Bacilli,1ZQAS@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family yyaE - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding HPHIIJEP_02013 224308.BSU40920 5.65e-256 702.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,1ZBUI@1386|Bacillus 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C HPHIIJEP_02014 224308.BSU40910 1.01e-61 189.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,1ZGZ0@1386|Bacillus 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 HPHIIJEP_02015 224308.BSU40900 1.81e-103 301.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,1ZFIJ@1386|Bacillus 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB HPHIIJEP_02016 224308.BSU40890 4.25e-49 156.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,1ZHUE@1386|Bacillus 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 HPHIIJEP_02017 224308.BSU40880 1.7e-186 517.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,1ZAS3@1386|Bacillus 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos HPHIIJEP_02018 224308.BSU40870 2.49e-229 630.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,1ZC0J@1386|Bacillus 91061|Bacilli K Transcriptional regulator ccpB - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 HPHIIJEP_02019 224308.BSU40860 7.2e-90 263.0 COG0346@1|root,COG0346@2|Bacteria,1V4NM@1239|Firmicutes,4HMRV@91061|Bacilli,1ZRTP@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yyaH - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase HPHIIJEP_02020 224308.BSU40850 3.81e-129 367.0 COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,4HEHH@91061|Bacilli,1ZBSX@1386|Bacillus 91061|Bacilli S Bacterial transferase hexapeptide (six repeats) vatD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008374,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044444,GO:0044464 2.3.1.28,2.3.1.79 ko:K00638,ko:K00661,ko:K18234 - - - - br01600,ko00000,ko01000,ko01504 - - - Hexapep HPHIIJEP_02021 224308.BSU40840 0.0 876.0 COG0477@1|root,COG0477@2|Bacteria,COG2814@2|Bacteria,1UY0B@1239|Firmicutes,4HERK@91061|Bacilli,1ZH7J@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily - - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr HPHIIJEP_02022 224308.BSU40830 2.35e-212 587.0 COG1266@1|root,COG1266@2|Bacteria,1VCI6@1239|Firmicutes,4HUC0@91061|Bacilli,1ZFTH@1386|Bacillus 91061|Bacilli S CAAX protease self-immunity yyaK - - ko:K07052 - - - - ko00000 - - - Abi HPHIIJEP_02023 224308.BSU40820 0.0 1387.0 COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,1ZCEN@1386|Bacillus 91061|Bacilli O COG1331 Highly conserved protein containing a thioredoxin domain yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH HPHIIJEP_02024 1384057.CD33_00700 6.81e-109 317.0 COG1305@1|root,COG1305@2|Bacteria,1TQ42@1239|Firmicutes,4HCDE@91061|Bacilli 91061|Bacilli E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core HPHIIJEP_02025 224308.BSU25810 5.99e-70 211.0 COG0640@1|root,COG0640@2|Bacteria,1V9XT@1239|Firmicutes,4HKP8@91061|Bacilli,1ZI0T@1386|Bacillus 91061|Bacilli K ArsR family transcriptional regulator arsR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 HPHIIJEP_02026 224308.BSU25790 3.95e-230 635.0 COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,4HC8A@91061|Bacilli,1ZD7K@1386|Bacillus 91061|Bacilli P Arsenic resistance protein arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - ko:K03325 - - - - ko00000,ko02000 2.A.59 - iYO844.BSU25790 SBF HPHIIJEP_02027 224308.BSU25780 4.49e-88 259.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,1ZFM2@1386|Bacillus 91061|Bacilli T Catalyzes the reduction of arsenate As(V) to arsenite As(III) arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc HPHIIJEP_02028 224308.BSU40770 3.67e-310 847.0 COG0477@1|root,COG2814@2|Bacteria,1TQWM@1239|Firmicutes,4HB5B@91061|Bacilli,1ZAQX@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily tetL GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1 HPHIIJEP_02029 1051501.AYTL01000028_gene1684 1.78e-24 101.0 COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,4H9ZS@91061|Bacilli,1ZCEN@1386|Bacillus 91061|Bacilli O COG1331 Highly conserved protein containing a thioredoxin domain yyaL - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Glyco_hydro_9,Thioredox_DsbH HPHIIJEP_02030 224308.BSU40760 4.99e-136 384.0 COG0262@1|root,COG0262@2|Bacteria,1TRY1@1239|Firmicutes,4HC69@91061|Bacilli,1ZRR0@1386|Bacillus 91061|Bacilli H RibD C-terminal domain yyaP - - - - - - - - - - - RibD_C HPHIIJEP_02031 224308.BSU40750 7.41e-86 252.0 COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,4HHQI@91061|Bacilli 91061|Bacilli S YjbR - - - - - - - - - - - - YjbR HPHIIJEP_02032 224308.BSU40740 2.42e-122 348.0 COG0454@1|root,COG0456@2|Bacteria,1V1D1@1239|Firmicutes,4HK2F@91061|Bacilli,1ZR23@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K19273 - - - - ko00000,ko01000,ko01504 - - - Acetyltransf_1 HPHIIJEP_02033 224308.BSU40730 6.6e-127 362.0 COG2364@1|root,COG2364@2|Bacteria,1V3NC@1239|Firmicutes,4HGRQ@91061|Bacilli,1ZCBH@1386|Bacillus 91061|Bacilli S Membrane yyaS - - ko:K07149 - - - - ko00000 - - - - HPHIIJEP_02034 224308.BSU40720 3.58e-91 268.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,1ZGIP@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 HPHIIJEP_02035 224308.BSU40710 4.54e-100 290.0 COG1846@1|root,COG1846@2|Bacteria,1V3PS@1239|Firmicutes,4HFN6@91061|Bacilli,1ZFRK@1386|Bacillus 91061|Bacilli K transcriptional yybA - - - - - - - - - - - MarR HPHIIJEP_02036 224308.BSU40700 2.52e-163 456.0 COG0491@1|root,COG0491@2|Bacteria,1TQGU@1239|Firmicutes,4HBJ3@91061|Bacilli,1ZQQH@1386|Bacillus 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B HPHIIJEP_02037 224308.BSU40690 2.64e-92 271.0 2BWFV@1|root,32QWV@2|Bacteria,1V8UN@1239|Firmicutes,4HK47@91061|Bacilli,1ZHNT@1386|Bacillus 91061|Bacilli - - yybC - - - - - - - - - - - DUF2798 HPHIIJEP_02038 224308.BSU40680 2.65e-102 296.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,1ZGIP@1386|Bacillus 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 HPHIIJEP_02039 224308.BSU40670 1.07e-209 579.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HDHR@91061|Bacilli,1ZQ2H@1386|Bacillus 91061|Bacilli K Transcriptional regulator yybE GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_02040 224308.BSU40660 2.17e-268 737.0 COG0477@1|root,COG2814@2|Bacteria,1TQKU@1239|Firmicutes,4HA5Q@91061|Bacilli,1ZCSQ@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yybF - - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1,Sugar_tr HPHIIJEP_02041 224308.BSU40650 2.56e-158 448.0 COG1357@1|root,COG1357@2|Bacteria,1TR7Y@1239|Firmicutes,4HBDH@91061|Bacilli,1ZBA0@1386|Bacillus 91061|Bacilli S Pentapeptide repeat-containing protein yybG - - - - - - - - - - - Pentapeptide HPHIIJEP_02042 224308.BSU40640 8.34e-86 253.0 COG4319@1|root,COG4319@2|Bacteria,1V5V3@1239|Firmicutes,4HIZV@91061|Bacilli,1ZGJ3@1386|Bacillus 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - DUF4440,SnoaL_3 HPHIIJEP_02043 224308.BSU40630 2.39e-182 508.0 28I7X@1|root,2Z8AS@2|Bacteria,1UTKU@1239|Firmicutes,4HHB9@91061|Bacilli,1ZS7U@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - VCBS HPHIIJEP_02044 720555.BATR1942_18415 5.1e-141 402.0 COG0789@1|root,COG0789@2|Bacteria,1UDUH@1239|Firmicutes,4HCYB@91061|Bacilli,1ZFST@1386|Bacillus 91061|Bacilli K TipAS antibiotic-recognition domain - - - - - - - - - - - - MerR_1,TipAS HPHIIJEP_02045 224308.BSU40570 1.01e-307 839.0 COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,4HEVA@91061|Bacilli,1ZCX2@1386|Bacillus 91061|Bacilli G COG0477 Permeases of the major facilitator superfamily yybO GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0044425,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03535,ko:K08191 - - - - ko00000,ko02000 2.A.1.14.1,2.A.1.14.2 - iYO844.BSU02480 MFS_1 HPHIIJEP_02047 224308.BSU40560 7.84e-91 267.0 2A2UI@1|root,30R8G@2|Bacteria,1TZ2Y@1239|Firmicutes,4I89Y@91061|Bacilli,1ZG0T@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02048 224308.BSU40550 4.01e-209 579.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,1ZBEH@1386|Bacillus 91061|Bacilli C Inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 HPHIIJEP_02049 224308.BSU40540 6.68e-90 263.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,1ZHCV@1386|Bacillus 91061|Bacilli K Transcriptional regulator yybR - - - - - - - - - - - HxlR HPHIIJEP_02050 224308.BSU40530 2.89e-110 317.0 COG5577@1|root,COG5577@2|Bacteria,1V91D@1239|Firmicutes,4HJ0J@91061|Bacilli,1ZGWF@1386|Bacillus 91061|Bacilli M Spore coat protein cotF - - ko:K06329 - - - - ko00000 - - - Coat_F HPHIIJEP_02052 224308.BSU40520 5.23e-205 569.0 COG4241@1|root,COG4241@2|Bacteria,1UZYE@1239|Firmicutes,4HAFH@91061|Bacilli,1ZC1B@1386|Bacillus 91061|Bacilli S membrane yybS - - - - - - - - - - - DUF2232 HPHIIJEP_02053 224308.BSU40510 0.0 1256.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,1ZCB0@1386|Bacillus 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 HPHIIJEP_02054 224308.BSU40500 2.74e-96 281.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,1ZGEE@1386|Bacillus 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N HPHIIJEP_02055 224308.BSU40490 0.0 1262.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,1ZCFV@1386|Bacillus 91061|Bacilli M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family ykcB - - - - - - - - - - - PMT_2 HPHIIJEP_02056 224308.BSU40480 4.19e-283 774.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,1ZC26@1386|Bacillus 91061|Bacilli P COG2807 Cyanate permease yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 HPHIIJEP_02057 224308.BSU40470 1.89e-22 86.7 COG3093@1|root,COG3093@2|Bacteria,1VNWW@1239|Firmicutes,4HRUI@91061|Bacilli,1ZK0J@1386|Bacillus 91061|Bacilli K YycC-like protein yycC - - - - - - - - - - - YycC HPHIIJEP_02059 224308.BSU40450 3.48e-40 132.0 2EDFP@1|root,337BX@2|Bacteria,1VGBD@1239|Firmicutes,4HRJ6@91061|Bacilli,1ZK2J@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2188) yycD - - - - - - - - - - - DUF2188 HPHIIJEP_02060 224308.BSU40440 0.0 869.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,1ZBUR@1386|Bacillus 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C HPHIIJEP_02061 224308.BSU40430 1.91e-98 285.0 COG0346@1|root,COG0346@2|Bacteria,1V4ST@1239|Firmicutes,4HHEE@91061|Bacilli,1ZFZT@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yycE - - - - - - - - - - - Glyoxalase HPHIIJEP_02062 1051501.AYTL01000028_gene1721 1.29e-314 856.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,1ZBF8@1386|Bacillus 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt HPHIIJEP_02067 224308.BSU40410 1.45e-172 481.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_02068 224308.BSU40400 0.0 1160.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,1ZCQI@1386|Bacillus 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 HPHIIJEP_02069 224308.BSU40390 0.0 897.0 COG4863@1|root,COG4863@2|Bacteria,1UV48@1239|Firmicutes,4HF30@91061|Bacilli,1ZD30@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycH - - - - - - - - - - - YycH HPHIIJEP_02070 224308.BSU40380 1.2e-200 555.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,1ZDGV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yycI - - - - - - - - - - - YycI HPHIIJEP_02071 224308.BSU40370 1.15e-190 529.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,1ZASY@1386|Bacillus 91061|Bacilli S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 HPHIIJEP_02072 224308.BSU40360 2.22e-277 759.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZBNF@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain yyxA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HPHIIJEP_02073 224308.BSU40350 0.0 899.0 COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HC5M@91061|Bacilli,1ZB0M@1386|Bacillus 91061|Bacilli KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains rocR GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K06714 - - - - ko00000,ko03000 - - - HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat HPHIIJEP_02074 224308.BSU40340 2.04e-294 803.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus 91061|Bacilli E Catalyzes the interconversion of ornithine to glutamate semialdehyde rocD GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.6.1.13 ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R00667 RC00006,RC00062 ko00000,ko00001,ko01000,ko01007 - - iYO844.BSU40340 Aminotran_3 HPHIIJEP_02075 224308.BSU40330 0.0 902.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus 91061|Bacilli E amino acid rocE GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 - ko:K02205,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iYO844.BSU39390 AA_permease HPHIIJEP_02076 224308.BSU40320 3.22e-213 588.0 COG0010@1|root,COG0010@2|Bacteria,1TR10@1239|Firmicutes,4HAT5@91061|Bacilli,1ZCJY@1386|Bacillus 91061|Bacilli E Belongs to the arginase family rocF GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 M00029,M00134 R00551 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase HPHIIJEP_02078 1051501.AYTL01000028_gene1733 1.23e-238 659.0 COG0457@1|root,COG0457@2|Bacteria,1UV2Q@1239|Firmicutes,4I405@91061|Bacilli,1ZF04@1386|Bacillus 1051501.AYTL01000028_gene1733|- S aspartate phosphatase - - - - - - - - - - - - - HPHIIJEP_02079 224308.BSU40290 1.24e-109 315.0 COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,1ZFP4@1386|Bacillus 91061|Bacilli K Acetyltransferase yycN - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_02080 224308.BSU40280 7.97e-168 469.0 COG3863@1|root,COG3863@2|Bacteria,1V69Q@1239|Firmicutes,4HIEK@91061|Bacilli,1ZHR3@1386|Bacillus 91061|Bacilli S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family yycO - - - - - - - - - - - Peptidase_C92 HPHIIJEP_02081 224308.BSU40270 2.31e-277 758.0 2E4ET@1|root,32Z9Z@2|Bacteria,1VIUZ@1239|Firmicutes,4HPKC@91061|Bacilli,1ZHK1@1386|Bacillus 91061|Bacilli - - yycP - - - - - - - - - - - - HPHIIJEP_02082 224308.BSU40260 1.07e-39 132.0 29RYM@1|root,30D2Z@2|Bacteria,1UARQ@1239|Firmicutes,4IM4G@91061|Bacilli,1ZJ4M@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2651) yycQ - - - - - - - - - - - DUF2651 HPHIIJEP_02084 224308.BSU40250 1.81e-297 811.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,1ZB9D@1386|Bacillus 91061|Bacilli E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases yycR - 1.1.1.1,1.1.1.284,1.2.1.46 ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00604,R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N HPHIIJEP_02085 224308.BSU40240 2.93e-83 247.0 2DKCH@1|root,32UEV@2|Bacteria,1VDU5@1239|Firmicutes,4HN5E@91061|Bacilli,1ZJIW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - YesK HPHIIJEP_02087 720555.BATR1942_18175 5e-106 306.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,1ZFK3@1386|Bacillus 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase HPHIIJEP_02088 1178540.BA70_11865 3.62e-179 499.0 arCOG09511@1|root,30J4W@2|Bacteria,1TTZR@1239|Firmicutes,4HZJ6@91061|Bacilli,1ZKB6@1386|Bacillus 91061|Bacilli S FRG - - - - - - - - - - - - FRG HPHIIJEP_02089 1178540.BA70_11870 2.95e-228 632.0 COG1479@1|root,COG1479@2|Bacteria,1V3XN@1239|Firmicutes,4HJ9V@91061|Bacilli,1ZK9H@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 HPHIIJEP_02090 1280666.ATVS01000053_gene623 2.22e-44 164.0 COG1672@1|root,COG1672@2|Bacteria 2|Bacteria - - - - - ko:K06921 - - - - ko00000 - - - DUF234,TIR_2 HPHIIJEP_02091 224308.BSU40190 0.0 1292.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,1ZE8H@1386|Bacillus 91061|Bacilli G Firmicute fructose-1,6-bisphosphatase fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 HPHIIJEP_02092 224308.BSU40150 1.39e-141 400.0 COG1131@1|root,COG1131@2|Bacteria,1V3UQ@1239|Firmicutes,4HIDP@91061|Bacilli,1ZMR9@1386|Bacillus 91061|Bacilli P ABC transporter - - - ko:K16917 ko02010,map02010 M00583 - - ko00000,ko00001,ko00002,ko02000 3.A.1.133.1 - - ABC_tran HPHIIJEP_02093 224308.BSU40140 5.49e-152 429.0 2EWB9@1|root,33PQ0@2|Bacteria,1VQYZ@1239|Firmicutes,4HT5C@91061|Bacilli,1ZMW8@1386|Bacillus 91061|Bacilli S ABC-2 family transporter protein - - - ko:K16916 ko02010,map02010 M00583 - - ko00000,ko00001,ko00002,ko02000 3.A.1.133.1 - - - HPHIIJEP_02094 224308.BSU40139 1.44e-24 92.4 2C0AP@1|root,2ZRKA@2|Bacteria,1W4E0@1239|Firmicutes,4I06F@91061|Bacilli,1ZP04@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02095 224308.BSU40130 8.29e-161 451.0 COG2188@1|root,COG2188@2|Bacteria,1V2M8@1239|Firmicutes,4HGRM@91061|Bacilli,1ZDVR@1386|Bacillus 91061|Bacilli K Transcriptional regulator yydK - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_02096 1051501.AYTL01000028_gene1748 9.47e-24 100.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZC3X@1386|Bacillus 91061|Bacilli G phosphotransferase system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_02097 224308.BSU40110 0.0 995.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 HPHIIJEP_02098 1340434.AXVA01000023_gene3375 1.58e-237 663.0 COG2327@1|root,COG2327@2|Bacteria,1TQDF@1239|Firmicutes,4HM0Z@91061|Bacilli,1ZCUH@1386|Bacillus 91061|Bacilli S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans HPHIIJEP_02099 224308.BSU40100 0.0 987.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli,1ZCRN@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 HPHIIJEP_02100 224308.BSU40090 9.33e-136 384.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli,1ZCZP@1386|Bacillus 91061|Bacilli O Alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA HPHIIJEP_02101 224308.BSU40080 0.0 943.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZBRV@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 HPHIIJEP_02102 224308.BSU40070 2.05e-295 809.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,1ZAYI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases gntP GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease HPHIIJEP_02103 224308.BSU40060 0.0 1041.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N HPHIIJEP_02104 224308.BSU40050 3.63e-163 457.0 COG1802@1|root,COG1802@2|Bacteria,1TSJY@1239|Firmicutes,4HBY3@91061|Bacilli,1ZCQF@1386|Bacillus 91061|Bacilli K transcriptional gntR - - ko:K11476 - - - - ko00000,ko03000 - - - FCD,GntR HPHIIJEP_02105 224308.BSU40040 1.11e-261 718.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,1ZC1D@1386|Bacillus 91061|Bacilli G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase HPHIIJEP_02106 224308.BSU40030 3.62e-245 673.0 COG5039@1|root,COG5039@2|Bacteria,1V5MK@1239|Firmicutes,4HB4G@91061|Bacilli,1ZR1U@1386|Bacillus 91061|Bacilli GM Polysaccharide pyruvyl transferase - - - ko:K19426 - - - - ko00000,ko01000 - - - PS_pyruv_trans HPHIIJEP_02107 224308.BSU40022 2.19e-153 432.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase yxaC - - - - - - - - - - - LrgB HPHIIJEP_02108 224308.BSU40021 1.03e-77 233.0 COG1380@1|root,COG1380@2|Bacteria,1VE19@1239|Firmicutes,4HMWP@91061|Bacilli,1ZQGW@1386|Bacillus 91061|Bacilli S LrgA family - - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA HPHIIJEP_02109 224308.BSU40010 6.83e-94 274.0 COG1846@1|root,COG1846@2|Bacteria,1V7G6@1239|Firmicutes,4HM9I@91061|Bacilli,1ZH4J@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR,MarR_2 HPHIIJEP_02110 224308.BSU40000 7.36e-166 468.0 COG1028@1|root,COG1028@2|Bacteria,1URGX@1239|Firmicutes,4HC4W@91061|Bacilli,1ZF92@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yxnA - - - - - - - - - - - adh_short HPHIIJEP_02111 224308.BSU40000 1.53e-43 150.0 COG1028@1|root,COG1028@2|Bacteria,1URGX@1239|Firmicutes,4HC4W@91061|Bacilli,1ZF92@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yxnA - - - - - - - - - - - adh_short HPHIIJEP_02112 224308.BSU39990 3.91e-130 370.0 COG1309@1|root,COG1309@2|Bacteria,1V7QU@1239|Firmicutes,4HJIT@91061|Bacilli,1ZGD2@1386|Bacillus 91061|Bacilli K Transcriptional regulator yxaF - - ko:K18939 - M00715 - - ko00000,ko00002,ko03000 - - - TetR_N HPHIIJEP_02113 224308.BSU39980 8.59e-250 684.0 COG1917@1|root,COG1917@2|Bacteria,1V0NH@1239|Firmicutes,4HFF0@91061|Bacilli,1ZEAB@1386|Bacillus 91061|Bacilli S AraC-like ligand binding domain - - 1.13.11.24 ko:K07155 - - - - ko00000,ko01000 - - - Cupin_2 HPHIIJEP_02114 224308.BSU39970 4.19e-283 774.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF418 HPHIIJEP_02115 224308.BSU39960 2.33e-98 286.0 COG1714@1|root,COG1714@2|Bacteria,1VIH4@1239|Firmicutes,4HSGI@91061|Bacilli,1ZF2E@1386|Bacillus 91061|Bacilli S membrane protein domain yxaI - - - - - - - - - - - RDD HPHIIJEP_02116 224308.BSU39950 3.79e-81 242.0 29RX6@1|root,34C2Q@2|Bacteria,1UAPG@1239|Firmicutes,4HY0W@91061|Bacilli,1ZISF@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5391) - - - - - - - - - - - - DUF5391 HPHIIJEP_02117 224308.BSU39940 7.49e-137 404.0 COG1520@1|root,COG1520@2|Bacteria,1V9TE@1239|Firmicutes,4HJ03@91061|Bacilli,1ZJSW@1386|Bacillus 91061|Bacilli S PQQ-like domain yxaL - - - - - - - - - - - Big_2,PQQ,PQQ_2,PQQ_3,SLH HPHIIJEP_02118 326423.RBAM_036940 2.93e-27 104.0 COG1714@1|root,COG1714@2|Bacteria,1VIH4@1239|Firmicutes,4HSGI@91061|Bacilli,1ZF2E@1386|Bacillus 91061|Bacilli S membrane protein domain yxaI - - - - - - - - - - - RDD HPHIIJEP_02119 224308.BSU39860 1.97e-312 852.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family aldX - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_02120 224308.BSU39850 8.49e-265 726.0 COG1309@1|root,COG1309@2|Bacteria,1UBJ1@1239|Firmicutes,4IMYN@91061|Bacilli,1ZM8W@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family yxbF GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_02121 224308.BSU39840 5.9e-193 535.0 COG1028@1|root,COG1028@2|Bacteria,1UYSA@1239|Firmicutes,4HBJJ@91061|Bacilli,1ZD29@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase yxbG - - - - - - - - - - - adh_short_C2 HPHIIJEP_02123 224308.BSU39820 0.0 1214.0 COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,4HD5Z@91061|Bacilli,1ZBHK@1386|Bacillus 91061|Bacilli O Molecular chaperone. Has ATPase activity htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c,HATPase_c_3,HSP90 HPHIIJEP_02124 224308.BSU39810 5.91e-313 855.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,1ZAUM@1386|Bacillus 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family csbC GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.26 - - Sugar_tr HPHIIJEP_02125 1051501.AYTL01000028_gene1780 2.13e-64 196.0 2DTR5@1|root,33MCD@2|Bacteria,1VH2H@1239|Firmicutes,4HQ9N@91061|Bacilli,1ZI67@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2653) yxcD - - - - - - - - - - - DUF2653 HPHIIJEP_02127 224308.BSU39780 2.04e-223 615.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,1ZCES@1386|Bacillus 91061|Bacilli C Aldo keto reductase iolS - - ko:K06607 - - - - ko00000,ko01000 - - - Aldo_ket_red HPHIIJEP_02128 224308.BSU39770 2.21e-177 494.0 COG1349@1|root,COG1349@2|Bacteria,1TTGR@1239|Firmicutes,4HEVD@91061|Bacilli,1ZDNC@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism iolR - - ko:K06608,ko:K11534 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR HPHIIJEP_02129 224308.BSU39760 0.0 975.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively iolA GO:0003674,GO:0003824,GO:0004491,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_02130 224308.BSU39750 4.9e-200 553.0 COG3718@1|root,COG3718@2|Bacteria,1TR6M@1239|Firmicutes,4HCDY@91061|Bacilli,1ZCS0@1386|Bacillus 91061|Bacilli G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) iolB - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI HPHIIJEP_02131 224308.BSU39740 3.52e-227 626.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HB78@91061|Bacilli,1ZCTX@1386|Bacillus 91061|Bacilli G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU39740 PfkB HPHIIJEP_02132 224308.BSU39730 0.0 1247.0 COG3962@1|root,COG3962@2|Bacteria,1UI18@1239|Firmicutes,4HCPP@91061|Bacilli,1ZCZJ@1386|Bacillus 91061|Bacilli E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - iYO844.BSU39730 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HPHIIJEP_02133 224308.BSU39720 4.99e-222 611.0 COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,1ZEF8@1386|Bacillus 91061|Bacilli G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) iolE - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 HPHIIJEP_02134 224308.BSU39710 3.44e-297 813.0 COG0477@1|root,COG2814@2|Bacteria,1TRBM@1239|Firmicutes,4HE7W@91061|Bacilli,1ZQ91@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily iolF GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06610 - - - - ko00000,ko02000 2.A.1.1.27 - - MFS_1,Sugar_tr HPHIIJEP_02135 224308.BSU39700 2.11e-249 684.0 COG0673@1|root,COG0673@2|Bacteria,1TRHA@1239|Firmicutes,4HA6R@91061|Bacilli,1ZENE@1386|Bacillus 91061|Bacilli S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively iolG - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_02136 224308.BSU39690 5.35e-213 587.0 COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,4HEG4@91061|Bacilli,1ZE6D@1386|Bacillus 91061|Bacilli G Xylose isomerase-like TIM barrel iolH - - ko:K06605 - - - - ko00000 - - - AP_endonuc_2 HPHIIJEP_02137 224308.BSU39680 4.24e-184 513.0 COG1082@1|root,COG1082@2|Bacteria,1TS20@1239|Firmicutes,4HD4V@91061|Bacilli,1ZCMI@1386|Bacillus 91061|Bacilli G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone) iolI - 5.3.99.11 ko:K06606 ko00562,ko01120,map00562,map01120 - R09952 RC01513 ko00000,ko00001,ko01000 - - - AP_endonuc_2 HPHIIJEP_02138 224308.BSU39670 6.95e-205 567.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZEJH@1386|Bacillus 91061|Bacilli F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP) fbaA - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase HPHIIJEP_02139 224308.BSU39660 2.8e-160 449.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAQ7@91061|Bacilli,1ZE1M@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yxdJ - - ko:K02483,ko:K11634 ko02020,map02020 M00470 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_02140 224308.BSU39650 7.73e-231 635.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HCB6@91061|Bacilli,1ZAPT@1386|Bacillus 91061|Bacilli T Histidine kinase yxdK - 2.7.13.3 ko:K11633 ko02020,map02020 M00470 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c HPHIIJEP_02141 1051501.AYTL01000028_gene1796 5.21e-179 499.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yxdL - - ko:K11635 ko02020,map02020 M00315 - - ko00000,ko00001,ko00002,ko02000 3.A.1.134.6 - - ABC_tran HPHIIJEP_02142 224308.BSU39630 0.0 1182.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAG9@91061|Bacilli,1ZB66@1386|Bacillus 91061|Bacilli V ABC transporter (permease) yxdM - - ko:K11636 ko02020,map02020 M00315 - - ko00000,ko00001,ko00002,ko02000 3.A.1.134.6 - - FtsX HPHIIJEP_02143 224308.BSU39620 5.95e-77 229.0 COG5294@1|root,COG5294@2|Bacteria,1VHCQ@1239|Firmicutes,4HNS8@91061|Bacilli,1ZJSA@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1093) yxeA - - - - - - - - - - - DUF1093 HPHIIJEP_02144 224308.BSU39610 3.51e-225 621.0 COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,4HBP4@91061|Bacilli,1ZBTM@1386|Bacillus 91061|Bacilli P ABC transporter fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 HPHIIJEP_02145 224308.BSU39600 9.65e-91 265.0 2DDWI@1|root,2ZJM0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HPHIIJEP_02146 224308.BSU39590 7.57e-28 105.0 2ED14@1|root,336Y2@2|Bacteria,1VJP8@1239|Firmicutes,4HS9Y@91061|Bacilli,1ZHAI@1386|Bacillus 91061|Bacilli - - yxeD - - - - - - - - - - - - HPHIIJEP_02147 224308.BSU39580 7.32e-42 141.0 2BBDR@1|root,324WV@2|Bacteria,1UAIT@1239|Firmicutes,4IKX9@91061|Bacilli,1ZI6G@1386|Bacillus 91061|Bacilli - - yxeE - - - - - - - - - - - - HPHIIJEP_02150 224308.BSU39550 8.09e-194 537.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,1ZCPY@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily yxeH - - - - - - - - - - - Hydrolase_3 HPHIIJEP_02151 224308.BSU39540 1.64e-238 655.0 COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,4HEQ3@91061|Bacilli,1ZM5U@1386|Bacillus 91061|Bacilli M Linear amide C-N hydrolases, choloylglycine hydrolase family yxeI - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH HPHIIJEP_02152 224308.BSU39520 0.0 883.0 COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,1ZBUG@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yxeK - - - - - - - - - - - Bac_luciferase HPHIIJEP_02153 224308.BSU39510 1.54e-121 346.0 COG0454@1|root,COG0456@2|Bacteria,1V9FA@1239|Firmicutes,4HJ4W@91061|Bacilli,1ZEY7@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yxeL - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_02154 224308.BSU39500 4.3e-186 517.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HNTP@91061|Bacilli,1ZFES@1386|Bacillus 91061|Bacilli M Belongs to the bacterial solute-binding protein 3 family yxeM - - ko:K16961 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 HPHIIJEP_02155 224308.BSU39490 6.05e-148 417.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli,1ZESX@1386|Bacillus 91061|Bacilli P COG0765 ABC-type amino acid transport system, permease component yxeN GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009,ko:K16962 ko02010,map02010 M00234,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 HPHIIJEP_02156 224308.BSU39480 1.32e-168 472.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZDVK@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein yxeO - - ko:K16960,ko:K16963 ko02010,map02010 M00585,M00586 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.13 - - ABC_tran HPHIIJEP_02157 224308.BSU39470 9.65e-271 741.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,1ZB09@1386|Bacillus 91061|Bacilli E hydrolase activity yxeP - - ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 HPHIIJEP_02158 224308.BSU39460 1.33e-310 847.0 COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,4HFIN@91061|Bacilli,1ZR1G@1386|Bacillus 91061|Bacilli S MmgE/PrpD family yxeQ GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 - - - - - - - - - - MmgE_PrpD HPHIIJEP_02159 224308.BSU39450 2.21e-255 701.0 COG3192@1|root,COG3192@2|Bacteria,1TNZF@1239|Firmicutes,4HAQ8@91061|Bacilli,1ZCSJ@1386|Bacillus 91061|Bacilli E Ethanolamine utilisation protein, EutH eutH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K04023 - - - - ko00000 - - iYO844.BSU39450 EutH HPHIIJEP_02160 224308.BSU39440 1.51e-196 545.0 2DBB1@1|root,2Z854@2|Bacteria,1TT9P@1239|Firmicutes,4HDSP@91061|Bacilli,1ZEVA@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1206) - - - - - - - - - - - - DUF1206 HPHIIJEP_02161 224308.BSU39430 1.22e-221 611.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,1ZD4S@1386|Bacillus 91061|Bacilli K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain deoR GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05346 - - - - ko00000,ko03000 - - - HTH_23,HTH_24,HTH_Crp_2,MarR_2,Sigma70_r4,Sugar-bind HPHIIJEP_02162 224308.BSU39420 1.18e-149 422.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iYO844.BSU39420 DeoC HPHIIJEP_02163 224308.BSU39410 1.92e-263 724.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family nupC GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 - ko:K11535 - - - - ko00000,ko02000 2.A.41.1 - iYO844.BSU39410 Gate,Nucleos_tra2_C,Nucleos_tra2_N HPHIIJEP_02164 224308.BSU39400 8.11e-299 816.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1ZBI1@1386|Bacillus 91061|Bacilli F phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C HPHIIJEP_02165 224308.BSU39390 0.0 872.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus 91061|Bacilli E amino acid ybgF GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 - ko:K02205,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iYO844.BSU39390 AA_permease HPHIIJEP_02166 224308.BSU39380 7.71e-228 627.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HCKQ@91061|Bacilli,1ZBPI@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - Arginase HPHIIJEP_02167 224308.BSU39370 7.47e-298 813.0 COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,1ZDE5@1386|Bacillus 91061|Bacilli Q Imidazolone-5-propionate hydrolase hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39370 Amidohydro_1,Amidohydro_3 HPHIIJEP_02168 224308.BSU39360 0.0 1106.0 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,1ZCMM@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N HPHIIJEP_02169 224308.BSU39350 0.0 978.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli,1ZC8Z@1386|Bacillus 91061|Bacilli E Histidine ammonia-lyase hutH - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39350 Lyase_aromatic HPHIIJEP_02170 224308.BSU39340 7.02e-103 297.0 28T9W@1|root,2ZFIH@2|Bacteria,1V1JV@1239|Firmicutes,4HFXV@91061|Bacilli,1ZGK3@1386|Bacillus 91061|Bacilli K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization hutP GO:0006082,GO:0006355,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031326,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0052803,GO:0052805,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1903506,GO:2000112,GO:2001141 - ko:K09683 - - - - ko00000,ko03000 - - - HutP HPHIIJEP_02171 224308.BSU39330 0.0 953.0 COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,4HBSN@91061|Bacilli,1ZDPS@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 43 family yxiA - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - GH43_C,Glyco_hydro_43,Laminin_G_3 HPHIIJEP_02172 768486.EHR_01785 9.39e-192 580.0 COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,4IQB6@91061|Bacilli,4B6RS@81852|Enterococcaceae 91061|Bacilli L Protein of unknown function (DUF2726) - - - - - - - - - - - - AAA_11,AAA_12,DUF2726 HPHIIJEP_02173 720555.BATR1942_17700 1.23e-78 234.0 COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,4HIP6@91061|Bacilli,1ZG7Z@1386|Bacillus 91061|Bacilli L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX HPHIIJEP_02174 720555.BATR1942_17695 0.0 1731.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,4HAJ1@91061|Bacilli,1ZAY8@1386|Bacillus 91061|Bacilli L HKD family nuclease - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII HPHIIJEP_02175 224308.BSU39320 1.78e-35 125.0 2EE98@1|root,3383N@2|Bacteria,1VGWV@1239|Firmicutes,4HQJB@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF5082) - - - - - - - - - - - - DUF5082 HPHIIJEP_02176 1051501.AYTL01000028_gene1829 1.56e-51 163.0 2CFFU@1|root,32ZHK@2|Bacteria,1VFDQ@1239|Firmicutes,4HRXU@91061|Bacilli,1ZJAX@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5344) yxiC - - - - - - - - - - - DUF5344 HPHIIJEP_02177 224308.BSU39300 2.36e-171 504.0 COG5444@1|root,COG5444@2|Bacteria,1V8G4@1239|Firmicutes,4ISX9@91061|Bacilli,1ZDRW@1386|Bacillus 91061|Bacilli S nuclease activity - - - ko:K21493 - - - - ko00000,ko01000,ko02048 - - - LXG,PT-TG HPHIIJEP_02178 169963.lmo0142 9.21e-44 145.0 2BD5A@1|root,326SZ@2|Bacteria,1V96B@1239|Firmicutes,4HIGB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02179 224308.BSU39270 0.0 1135.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZC3X@1386|Bacillus 91061|Bacilli G phosphotransferase system bglP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC HPHIIJEP_02180 224308.BSU39260 0.0 955.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 HPHIIJEP_02181 224308.BSU39250 8.5e-95 277.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4IRSH@91061|Bacilli,1ZJAT@1386|Bacillus 91061|Bacilli T Belongs to the universal stress protein A family yxiE - - - - - - - - - - - Usp HPHIIJEP_02182 720555.BATR1942_17630 3.89e-158 445.0 COG4340@1|root,COG4340@2|Bacteria 2|Bacteria E 2OG-Fe dioxygenase - - 1.14.11.45 ko:K20418 - - - - ko00000,ko01000 - - - 2OG-Fe_Oxy_2 HPHIIJEP_02183 720555.BATR1942_17625 5.76e-162 455.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bacC - 1.1.1.385 ko:K19548 ko01130,map01130 M00787 R10917 RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 HPHIIJEP_02184 224308.BSU39240 6.2e-212 587.0 COG0697@1|root,COG0697@2|Bacteria,1UAMA@1239|Firmicutes,4HA84@91061|Bacilli,1ZET8@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yxxF - - - - - - - - - - - EamA HPHIIJEP_02185 224308.BSU39230 0.0 3937.0 COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,1ZDH9@1386|Bacillus 91061|Bacilli M COG3209 Rhs family protein wapA GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - - - - - - - - - - RHS_repeat HPHIIJEP_02187 1051501.AYTL01000028_gene1843 3.42e-173 486.0 29QTC@1|root,30BT9@2|Bacteria,1U8MN@1239|Firmicutes,4IIJP@91061|Bacilli,1ZNP6@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02188 224308.BSU39160 2.66e-107 310.0 2BVWY@1|root,32U73@2|Bacteria,1VCA8@1239|Firmicutes,4HMAC@91061|Bacilli,1ZG90@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2716) yxiI - - - - - - - - - - - DUF2716 HPHIIJEP_02189 224308.BSU39150 4.75e-57 177.0 2A1BF@1|root,30PIA@2|Bacteria,1UB22@1239|Firmicutes,4IMEY@91061|Bacilli,1ZJZS@1386|Bacillus 91061|Bacilli S YxiJ-like protein yxiJ - - - - - - - - - - - YxiJ HPHIIJEP_02192 224308.BSU39120 7.94e-271 741.0 COG2755@1|root,COG3401@1|root,COG2755@2|Bacteria,COG3401@2|Bacteria,1UZJV@1239|Firmicutes,4HUHE@91061|Bacilli,1ZM72@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_02193 224308.BSU39110 0.0 927.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBR4@91061|Bacilli,1ZB39@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes dbpA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C HPHIIJEP_02194 224308.BSU39100 5.4e-292 799.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus 91061|Bacilli S COG2270 Permeases of the major facilitator superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 HPHIIJEP_02195 224308.BSU39090 9.2e-144 407.0 29T3N@1|root,30EA7@2|Bacteria,1UCB4@1239|Firmicutes,4INTI@91061|Bacilli,1ZNXJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02196 224308.BSU39080 5.66e-193 536.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,1ZDB0@1386|Bacillus 91061|Bacilli K transcriptional antiterminator licT GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD HPHIIJEP_02197 224308.BSU39070 3.18e-183 509.0 COG2273@1|root,COG2273@2|Bacteria,1UY13@1239|Firmicutes,4IPYG@91061|Bacilli,1ZRF1@1386|Bacillus 91061|Bacilli M licheninase activity bglS GO:0005575,GO:0005576 - - - - - - - - - - Glyco_hydro_16 HPHIIJEP_02198 224308.BSU39060 1.64e-283 777.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,1ZCEQ@1386|Bacillus 91061|Bacilli C Citrate transporter citH GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K03300,ko:K11639 ko02020,map02020 - - - ko00000,ko00001 2.A.11,2.A.11.1.1 - - CitMHS HPHIIJEP_02199 224308.BSU39050 0.0 1390.0 COG0693@1|root,COG0753@1|root,COG0693@2|Bacteria,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katE GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel,DJ-1_PfpI HPHIIJEP_02200 224308.BSU39040 9.65e-65 197.0 2CI5E@1|root,32S7D@2|Bacteria,1VA1W@1239|Firmicutes,4HKCJ@91061|Bacilli,1ZHWY@1386|Bacillus 91061|Bacilli - - yxiS - - - - - - - - - - - - HPHIIJEP_02201 1051501.AYTL01000028_gene1858 6.23e-135 384.0 COG5513@1|root,COG5513@2|Bacteria,1VD7B@1239|Firmicutes,4IT9B@91061|Bacilli,1ZI85@1386|Bacillus 91061|Bacilli T Domain of unknown function (DUF4163) - - - - - - - - - - - - DUF3298,DUF4163,SH3_3 HPHIIJEP_02202 224308.BSU39020 2.1e-269 739.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family nupG GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015212,GO:0015213,GO:0015214,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015506,GO:0015672,GO:0015858,GO:0015861,GO:0015862,GO:0015864,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072531,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1901505,GO:1901642,GO:1902600 - ko:K16323 - - - - ko00000,ko02000 2.A.41.1 - - Nucleos_tra2_C,Nucleos_tra2_N HPHIIJEP_02203 224308.BSU39010 2.83e-200 555.0 COG0500@1|root,COG0500@2|Bacteria,1UIYH@1239|Firmicutes,4ISX8@91061|Bacilli,1ZS7T@1386|Bacillus 91061|Bacilli Q Methyltransferase domain yxjB - 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25 HPHIIJEP_02204 224308.BSU39000 0.0 882.0 COG2610@1|root,COG2610@2|Bacteria,1TQJ6@1239|Firmicutes,4HA01@91061|Bacilli,1ZCGI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases yxjC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - GntP_permease HPHIIJEP_02205 224308.BSU38990 1.56e-166 466.0 COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,4HB3E@91061|Bacilli,1ZCXP@1386|Bacillus 91061|Bacilli I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans HPHIIJEP_02206 224308.BSU38980 5.91e-151 424.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans HPHIIJEP_02207 224308.BSU38970 5.83e-176 491.0 COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,4HACT@91061|Bacilli,1ZDEW@1386|Bacillus 91061|Bacilli IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate yxjF - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 HPHIIJEP_02208 224308.BSU38960 1.09e-275 753.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,1ZDE8@1386|Bacillus 91061|Bacilli E Methionine synthase yxjG - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 HPHIIJEP_02209 224308.BSU38950 1.5e-277 758.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,1ZDE8@1386|Bacillus 91061|Bacilli E Methionine synthase yxjG - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 HPHIIJEP_02210 224308.BSU38940 2.88e-111 320.0 COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,4HJ82@91061|Bacilli,1ZQ5F@1386|Bacillus 91061|Bacilli S LURP-one-related yxjI - - - - - - - - - - - LOR HPHIIJEP_02213 224308.BSU38920 7.76e-299 815.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,1ZCZN@1386|Bacillus 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 HPHIIJEP_02214 224308.BSU38910 2.69e-148 418.0 COG2197@1|root,COG2197@2|Bacteria,1V30W@1239|Firmicutes,4HT1P@91061|Bacilli,1ZGDR@1386|Bacillus 91061|Bacilli K helix_turn_helix, Lux Regulon - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg HPHIIJEP_02215 224308.BSU38900 9.25e-257 708.0 COG4585@1|root,COG4585@2|Bacteria,1TRFX@1239|Firmicutes,4HD1M@91061|Bacilli,1ZDHA@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase - - - - - - - - - - - - AAA_16,GAF,HATPase_c,HisKA_3,Pkinase HPHIIJEP_02216 224308.BSU38890 1.89e-100 292.0 arCOG10684@1|root,2ZSI3@2|Bacteria,1W1ZH@1239|Firmicutes,4I1FS@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1453) - - - - - - - - - - - - DUF1453 HPHIIJEP_02217 224308.BSU38880 4.73e-208 575.0 COG0583@1|root,COG0583@2|Bacteria,1UYA4@1239|Firmicutes,4HHV2@91061|Bacilli,1ZFDM@1386|Bacillus 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_02218 224308.BSU38870 1.16e-122 349.0 COG1881@1|root,COG1881@2|Bacteria,1V88T@1239|Firmicutes,4IRQA@91061|Bacilli,1ZMY1@1386|Bacillus 91061|Bacilli S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP HPHIIJEP_02219 224308.BSU38860 2.11e-251 689.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1ZB5V@1386|Bacillus 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd HPHIIJEP_02220 326423.RBAM_036070 4.99e-100 295.0 2DY9G@1|root,348S7@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4352) yxkC - - - - - - - - - - - DUF4352 HPHIIJEP_02221 224308.BSU38840 2.29e-188 524.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZD69@1386|Bacillus 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yxkD - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_02222 224308.BSU38830 0.0 942.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAXK@1386|Bacillus 91061|Bacilli C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively aldY GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0018479,GO:0055114 1.2.1.3,1.2.1.67 ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05699,R06366,R08146 RC00047,RC00071,RC00075,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38830 Aldedh HPHIIJEP_02223 224308.BSU38820 5.53e-210 580.0 COG2508@1|root,COG2508@2|Bacteria,1V649@1239|Firmicutes,4HHCD@91061|Bacilli,1ZH98@1386|Bacillus 91061|Bacilli QT PucR C-terminal helix-turn-helix domain lrp - - - - - - - - - - - HTH_30 HPHIIJEP_02224 224308.BSU38810 3.44e-261 716.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,1ZBDW@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 HPHIIJEP_02225 224308.BSU38800 1.3e-199 553.0 COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli,1ZQ8K@1386|Bacillus 91061|Bacilli G Polysaccharide deacetylase yxkH - - - - - - - - - - - Polysacc_deac_1,SLAP HPHIIJEP_02227 224308.BSU38780 0.0 1072.0 COG0501@1|root,COG0501@2|Bacteria,1U88Z@1239|Firmicutes,4HF3W@91061|Bacilli,1ZQAN@1386|Bacillus 91061|Bacilli O Peptidase family M48 - - - - - - - - - - - - Peptidase_M48 HPHIIJEP_02228 224308.BSU38770 2.67e-308 842.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter cimH - - - - - - - - - - - 2HCT HPHIIJEP_02229 224308.BSU38760 0.0 929.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I HPHIIJEP_02230 224308.BSU38750 1.16e-243 669.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,1ZDGQ@1386|Bacillus 91061|Bacilli C Cytochrome d ubiquinol oxidase, subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II HPHIIJEP_02231 224308.BSU38740 0.0 1059.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,1ZB86@1386|Bacillus 91061|Bacilli V ATP-binding cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran HPHIIJEP_02232 224308.BSU38730 0.0 1087.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,1ZCKI@1386|Bacillus 91061|Bacilli V ATP-binding protein cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran HPHIIJEP_02233 224308.BSU38720 1.52e-201 557.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,1ZAP7@1386|Bacillus 91061|Bacilli G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N HPHIIJEP_02234 224308.BSU38710 0.0 882.0 COG1457@1|root,COG1457@2|Bacteria,1V5JP@1239|Firmicutes,4HIHK@91061|Bacilli,1ZCP8@1386|Bacillus 91061|Bacilli F Belongs to the purine-cytosine permease (2.A.39) family yxlA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03457 - - - - ko00000 2.A.39 - iYO844.BSU38710 Transp_cyt_pur HPHIIJEP_02235 224308.BSU38700 3.69e-124 353.0 COG1595@1|root,COG1595@2|Bacteria,1VB37@1239|Firmicutes,4HMZ2@91061|Bacilli,1ZCWY@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigY - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HPHIIJEP_02236 224308.BSU38690 1.3e-60 187.0 295E2@1|root,2ZSRV@2|Bacteria,1W5NR@1239|Firmicutes,4I1KQ@91061|Bacilli,1ZJPN@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5345) yxlC - - - - - - - - - - - DUF5345 HPHIIJEP_02237 224308.BSU38680 1.63e-39 131.0 2DJGR@1|root,3062I@2|Bacteria,1TZ34@1239|Firmicutes,4HZY3@91061|Bacilli,1ZK0K@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02238 224308.BSU38670 2.17e-39 130.0 2DPPC@1|root,332VC@2|Bacteria,1VM0N@1239|Firmicutes,4HNHT@91061|Bacilli,1ZIVE@1386|Bacillus 91061|Bacilli S Phospholipase_D-nuclease N-terminal yxlE - - - - - - - - - - - PLDc_N HPHIIJEP_02239 224308.BSU38660 3.47e-212 586.0 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,1ZBR2@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 HPHIIJEP_02240 224308.BSU38650 1.61e-178 498.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HEAP@91061|Bacilli,1ZCZZ@1386|Bacillus 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component yxlG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_5 HPHIIJEP_02241 224308.BSU38640 2.37e-272 747.0 COG0477@1|root,COG2814@2|Bacteria,1TWWZ@1239|Firmicutes,4HEV3@91061|Bacilli,1ZCPX@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily yxlH GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_02242 224308.BSU38630 0.0 1122.0 COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,4H9XQ@91061|Bacilli,1ZB44@1386|Bacillus 91061|Bacilli P serves to protect cells from the toxic effects of hydrogen peroxide katX GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel HPHIIJEP_02243 224308.BSU38620 3.23e-145 408.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HG5E@91061|Bacilli,1ZFWT@1386|Bacillus 91061|Bacilli L Belongs to the DNA glycosylase MPG family yxlJ GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco HPHIIJEP_02244 224308.BSU38610 8.94e-28 100.0 2BT1W@1|root,32N67@2|Bacteria,1UB79@1239|Firmicutes,4IMJZ@91061|Bacilli,1ZKBI@1386|Bacillus 91061|Bacilli - - yxzF - - - - - - - - - - - - HPHIIJEP_02245 224308.BSU38600 0.0 1241.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1ZQ0I@1386|Bacillus 91061|Bacilli GKT Mga helix-turn-helix domain licR - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB HPHIIJEP_02246 224308.BSU38590 1.89e-67 204.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HM5Q@91061|Bacilli,1ZIC3@1386|Bacillus 91061|Bacilli G transporter subunit IIB licB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB HPHIIJEP_02247 224308.BSU38580 0.0 869.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1ZBJ7@1386|Bacillus 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC HPHIIJEP_02248 224308.BSU38570 6.85e-67 203.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,1ZI2Z@1386|Bacillus 91061|Bacilli G phosphotransferase system licA - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - iYO844.BSU38570 PTS_IIA HPHIIJEP_02249 224308.BSU38560 0.0 876.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,1ZC6U@1386|Bacillus 91061|Bacilli G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases licH - 3.2.1.86 ko:K01222 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT4 - Glyco_hydro_4,Glyco_hydro_4C HPHIIJEP_02250 224308.BSU38550 1.77e-262 719.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,1ZBFM@1386|Bacillus 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 HPHIIJEP_02251 224308.BSU38540 2.91e-178 496.0 COG3967@1|root,COG3967@2|Bacteria,1TT89@1239|Firmicutes,4HC2F@91061|Bacilli,1ZBB6@1386|Bacillus 91061|Bacilli M Belongs to the short-chain dehydrogenases reductases (SDR) family dltE - - ko:K14189 - - - - ko00000,ko01000 - - - adh_short HPHIIJEP_02252 224308.BSU38530 4.09e-294 801.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,1ZD6Q@1386|Bacillus 91061|Bacilli M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD HPHIIJEP_02253 1051501.AYTL01000028_gene1911 6.83e-50 158.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,1ZJEB@1386|Bacillus 91061|Bacilli IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding HPHIIJEP_02254 224308.BSU38510 1.14e-297 810.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,1ZCX1@1386|Bacillus 91061|Bacilli M membrane protein involved in D-alanine export dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT HPHIIJEP_02255 224308.BSU38500 0.0 1005.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C HPHIIJEP_02256 224308.BSU38490 5.1e-213 589.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,1ZB6F@1386|Bacillus 91061|Bacilli H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA HPHIIJEP_02257 224308.BSU38480 2.52e-149 420.0 COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,4HBE0@91061|Bacilli,1ZB8W@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ywaC GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951,ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT HPHIIJEP_02258 224308.BSU38470 0.0 866.0 COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HBE5@91061|Bacilli,1ZC0A@1386|Bacillus 91061|Bacilli S PA domain ywaD - 3.4.11.10,3.4.11.6 ko:K19701 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28 HPHIIJEP_02259 224308.BSU38460 2.22e-297 811.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b HPHIIJEP_02260 224308.BSU38450 1.46e-113 326.0 COG1846@1|root,COG1846@2|Bacteria,1VM7T@1239|Firmicutes,4I35C@91061|Bacilli,1ZGG4@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywaE GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_02261 224308.BSU38440 1.17e-156 441.0 COG5522@1|root,COG5522@2|Bacteria,1V4XE@1239|Firmicutes,4HHC6@91061|Bacilli,1ZBDN@1386|Bacillus 91061|Bacilli S Integral membrane protein ywaF - - - - - - - - - - - Intg_mem_TP0381 HPHIIJEP_02262 224308.BSU38430 6.53e-217 597.0 COG1442@1|root,COG1442@2|Bacteria,1V2FM@1239|Firmicutes,4HFSG@91061|Bacilli,1ZCME@1386|Bacillus 91061|Bacilli M General stress gspA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 - - - - - - - - - - Glyco_transf_8 HPHIIJEP_02263 224308.BSU38420 2.6e-195 542.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,1ZDB0@1386|Bacillus 91061|Bacilli K transcriptional antiterminator sacT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD HPHIIJEP_02264 224308.BSU38410 1.45e-312 853.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system sacX GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC HPHIIJEP_02265 224308.BSU38400 0.0 987.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family epr GO:0005575,GO:0005576 3.4.21.62 ko:K01342,ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Peptidase_S8,SLH,fn3 HPHIIJEP_02266 224308.BSU38390 1.59e-315 860.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,1ZBJ7@1386|Bacillus 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane licC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - iYO844.BSU38390 PTS_EIIC HPHIIJEP_02267 224308.BSU38380 1.02e-160 450.0 29A5D@1|root,2ZX6E@2|Bacteria,1W34Q@1239|Firmicutes,4I1DM@91061|Bacilli,1ZMSX@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2711) ywbB - - - - - - - - - - - DUF2711 HPHIIJEP_02268 224308.BSU38370 8.1e-87 255.0 COG0346@1|root,COG0346@2|Bacteria,1V7GY@1239|Firmicutes,4HIYA@91061|Bacilli,1ZH3E@1386|Bacillus 91061|Bacilli E glyoxalase ywbC - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase,Glyoxalase_4 HPHIIJEP_02269 224308.BSU38360 1.4e-280 767.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli,1ZBVG@1386|Bacillus 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM HPHIIJEP_02270 224308.BSU38350 3.13e-38 127.0 COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,1ZIX5@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2196) ywbE - - - - - - - - - - - DUF2196 HPHIIJEP_02271 224308.BSU38340 4.93e-267 733.0 COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1ZS79@1386|Bacillus 91061|Bacilli EGP Nucleoside H+ symporter ywbF - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like HPHIIJEP_02272 224308.BSU38330 1.21e-143 407.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli,1ZFQ6@1386|Bacillus 91061|Bacilli M effector of murein hydrolase ywbG - - - - - - - - - - - LrgB HPHIIJEP_02273 1051501.AYTL01000028_gene1932 2.21e-76 229.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,4HNKZ@91061|Bacilli,1ZGVJ@1386|Bacillus 91061|Bacilli S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a ywbH - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA HPHIIJEP_02274 224308.BSU38310 2.7e-203 564.0 COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,4HB94@91061|Bacilli,1ZBXV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywbI GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_02275 224308.BSU38300 1.32e-184 514.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,1ZAX2@1386|Bacillus 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008972,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK HPHIIJEP_02276 224308.BSU38290 7.07e-146 412.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,1ZFNE@1386|Bacillus 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38290 TMP-TENI HPHIIJEP_02277 224308.BSU38280 0.0 867.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,1ZDYA@1386|Bacillus 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 HPHIIJEP_02278 224308.BSU38270 2.94e-247 682.0 COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli,1ZC6N@1386|Bacillus 91061|Bacilli P periplasmic lipoprotein involved in iron transport ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K07224 - - - - ko00000,ko02000 2.A.108.2.3 - - Peptidase_M75 HPHIIJEP_02279 224308.BSU38260 1.72e-305 832.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,1ZEAD@1386|Bacillus 91061|Bacilli P Dyp-type peroxidase family protein ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal HPHIIJEP_02280 224308.BSU38250 1.32e-143 405.0 COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,1ZD4M@1386|Bacillus 91061|Bacilli Q dithiol-disulfide isomerase involved in polyketide biosynthesis ywbO - - - - - - - - - - - DSBA HPHIIJEP_02281 224308.BSU38240 0.0 924.0 COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,4HCF6@91061|Bacilli,1ZCX7@1386|Bacillus 91061|Bacilli S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family ywcA - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF HPHIIJEP_02282 224308.BSU38230 2.13e-64 196.0 COG3162@1|root,COG3162@2|Bacteria,1VAEW@1239|Firmicutes,4HM0S@91061|Bacilli,1ZHX2@1386|Bacillus 91061|Bacilli S Protein of unknown function, DUF485 ywcB - - - - - - - - - - - DUF485 HPHIIJEP_02284 224308.BSU38220 3.42e-158 443.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator ywcC - - - - - - - - - - - TetR_N HPHIIJEP_02285 224308.BSU38210 3.33e-77 231.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,1ZG2Y@1386|Bacillus 91061|Bacilli S GtrA-like protein gtcA - - - - - - - - - - - GtrA HPHIIJEP_02286 224308.BSU38200 4.38e-288 786.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,1ZC9P@1386|Bacillus 91061|Bacilli G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg HPHIIJEP_02287 224308.BSU38190 0.0 1038.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,1ZAVT@1386|Bacillus 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf HPHIIJEP_02288 224308.BSU38180 5.11e-49 156.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,1ZJBG@1386|Bacillus 91061|Bacilli S membrane ydaS - - - - - - - - - - - Transgly_assoc HPHIIJEP_02289 224308.BSU38170 6.94e-226 623.0 COG1622@1|root,COG1622@2|Bacteria,1TPF6@1239|Firmicutes,4HA9J@91061|Bacilli,1ZB28@1386|Bacillus 91061|Bacilli C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I qoxA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600 1.10.3.12 ko:K02826 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - iSB619.SA_RS05175 COX2,COX2_TM HPHIIJEP_02290 224308.BSU38160 0.0 1305.0 COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,4HA4X@91061|Bacilli,1ZBD5@1386|Bacillus 91061|Bacilli C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B qoxB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901564,GO:1902600 1.10.3.12 ko:K02827 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 3.D.4.1 - - COX1 HPHIIJEP_02291 224308.BSU38150 1.2e-144 407.0 COG1845@1|root,COG1845@2|Bacteria,1TQJ1@1239|Firmicutes,4HCWH@91061|Bacilli,1ZDEX@1386|Bacillus 91061|Bacilli C quinol oxidase, subunit qoxC GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02828 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX3 HPHIIJEP_02292 224308.BSU38140 1.12e-83 247.0 COG3125@1|root,COG3125@2|Bacteria,1VFT1@1239|Firmicutes,4HQ12@91061|Bacilli,1ZJ46@1386|Bacillus 91061|Bacilli C quinol oxidase, subunit qoxD GO:0003674,GO:0003824,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12 ko:K02829 ko00190,ko01100,map00190,map01100 M00416 R09492 RC00819 ko00000,ko00001,ko00002,ko01000 - - - COX4_pro HPHIIJEP_02293 1051501.AYTL01000028_gene1953 6.61e-52 164.0 2EPRF@1|root,33HBX@2|Bacteria,1VP6R@1239|Firmicutes,4HRWK@91061|Bacilli,1ZIF1@1386|Bacillus 91061|Bacilli S Required for proper spore morphogenesis. Important for spore germination ywcE GO:0008150,GO:0009847,GO:0032502 - - - - - - - - - - YwcE HPHIIJEP_02294 224308.BSU38120 8.89e-269 737.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,1ZBSB@1386|Bacillus 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE HPHIIJEP_02295 224308.BSU38110 1.98e-179 499.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,1ZBQ3@1386|Bacillus 91061|Bacilli C Oxidoreductase nfrA1 - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase HPHIIJEP_02296 224308.BSU38100 3.44e-238 655.0 COG2141@1|root,COG2141@2|Bacteria,1TPRS@1239|Firmicutes,4H9R2@91061|Bacilli,1ZB1E@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases ywcH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase HPHIIJEP_02297 224308.BSU38090 0.0 1541.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,1ZBS0@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family prtS GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FIVAR,FlgD_ig,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,YSIRK_signal,fn3_5 HPHIIJEP_02299 224308.BSU38070 2.6e-193 536.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,1ZDB0@1386|Bacillus 91061|Bacilli K transcriptional antiterminator sacT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD HPHIIJEP_02300 224308.BSU38060 2.79e-178 497.0 COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,4HC15@91061|Bacilli,1ZDNX@1386|Bacillus 91061|Bacilli P Formate/nitrite transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015112,GO:0015291,GO:0015318,GO:0015513,GO:0015698,GO:0015706,GO:0015707,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0071944,GO:0098656 - ko:K02598 - - - - ko00000,ko02000 1.A.16.3 - - Form_Nir_trans HPHIIJEP_02301 224308.BSU38050 0.0 884.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,1ZB5X@1386|Bacillus 91061|Bacilli G phosphotransferase system sacP GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.211 ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - iYO844.BSU38050 PTS_EIIB,PTS_EIIC HPHIIJEP_02302 224308.BSU38040 0.0 974.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus 91061|Bacilli G invertase sacA - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 iYO844.BSU38040 Glyco_hydro_32C,Glyco_hydro_32N HPHIIJEP_02303 720555.BATR1942_16905 6.19e-39 130.0 2CEZ0@1|root,307S6@2|Bacteria,1U24I@1239|Firmicutes,4IBN7@91061|Bacilli,1ZH61@1386|Bacillus 91061|Bacilli - - ywdA - - - - - - - - - - - - HPHIIJEP_02304 224308.BSU38020 9e-187 520.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli,1ZQ7W@1386|Bacillus 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35,2.7.1.49,2.7.4.7 ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 M00127 R00174,R01909,R02493,R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin HPHIIJEP_02305 224308.BSU38018 7.92e-76 226.0 COG1695@1|root,COG1695@2|Bacteria,1V4NA@1239|Firmicutes,4HHWW@91061|Bacilli,1ZINR@1386|Bacillus 91061|Bacilli K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR HPHIIJEP_02306 224308.BSU38000 3.56e-145 409.0 28MY0@1|root,2ZB4Y@2|Bacteria,1V0KB@1239|Firmicutes,4HE2C@91061|Bacilli,1ZE6E@1386|Bacillus 91061|Bacilli - - ywdD - - - - - - - - - - - - HPHIIJEP_02308 224308.BSU37980 4.68e-192 533.0 COG1216@1|root,COG1216@2|Bacteria,1TP40@1239|Firmicutes,4HDDN@91061|Bacilli,1ZE37@1386|Bacillus 91061|Bacilli S Glycosyltransferase like family 2 ywdF GO:0003674,GO:0003824,GO:0016740,GO:0016757 - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02309 224308.BSU37970 9.47e-166 462.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,1ZBCY@1386|Bacillus 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG HPHIIJEP_02310 224308.BSU37960 0.0 896.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family ywdH - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_02311 224308.BSU37950 2.18e-63 194.0 2DRJS@1|root,33C32@2|Bacteria,1VPJY@1239|Firmicutes,4HRSY@91061|Bacilli,1ZHM5@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5327) ywdI - - - - - - - - - - - DUF5327 HPHIIJEP_02312 224308.BSU37940 3.08e-302 826.0 COG2233@1|root,COG2233@2|Bacteria,1TQ0A@1239|Firmicutes,4HA6X@91061|Bacilli,1ZD5W@1386|Bacillus 91061|Bacilli F Xanthine uracil ywdJ GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - - - - - - - - - - Xan_ur_permease HPHIIJEP_02313 224308.BSU37930 1.59e-78 234.0 COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,1ZGYJ@1386|Bacillus 91061|Bacilli S small membrane protein ywdK - - - - - - - - - - - DUF423 HPHIIJEP_02314 224308.BSU37920 3.62e-112 323.0 2CWP1@1|root,32T03@2|Bacteria,1VAD2@1239|Firmicutes,4HKGQ@91061|Bacilli,1ZH2J@1386|Bacillus 91061|Bacilli S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA gerQ GO:0005575,GO:0005618,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0019538,GO:0030312,GO:0031160,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0071944,GO:1901564 - ko:K06305 - - - - ko00000 - - - Spore_GerQ HPHIIJEP_02315 224308.BSU37910 8.08e-187 518.0 COG0463@1|root,COG0463@2|Bacteria,1VTPH@1239|Firmicutes,4HUD5@91061|Bacilli,1ZDZ5@1386|Bacillus 91061|Bacilli M Spore Coat spsA - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02316 224308.BSU37900 0.0 917.0 COG1887@1|root,COG1887@2|Bacteria,1VVE5@1239|Firmicutes,4HWEM@91061|Bacilli,1ZE0J@1386|Bacillus 91061|Bacilli M Capsule polysaccharide biosynthesis protein spsB - - - - - - - - - - - Capsule_synth,Glyphos_transf HPHIIJEP_02317 224308.BSU37890 3.73e-284 776.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,1ZQW8@1386|Bacillus 91061|Bacilli E Belongs to the DegT DnrJ EryC1 family spsC - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 HPHIIJEP_02318 224308.BSU37880 4.22e-210 580.0 COG0454@1|root,COG0456@2|Bacteria,1V4XR@1239|Firmicutes,4I182@91061|Bacilli,1ZET7@1386|Bacillus 91061|Bacilli K Spore Coat spsD GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.210 ko:K16704 - - - - ko00000,ko01000 - - - Acetyltransf_1 HPHIIJEP_02319 224308.BSU37870 7.6e-269 736.0 COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,4HA1Y@91061|Bacilli,1ZBZ4@1386|Bacillus 91061|Bacilli M acid synthase pseI - 2.5.1.56,2.5.1.97 ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 - R01804,R04435,R09841 RC00159 ko00000,ko00001,ko01000 - - - NeuB,SAF HPHIIJEP_02320 224308.BSU37860 2.58e-166 465.0 COG1861@1|root,COG1861@2|Bacteria,1U4YD@1239|Firmicutes,4HE69@91061|Bacilli,1ZE65@1386|Bacillus 91061|Bacilli M Spore Coat spsF - - ko:K07257 - - - - ko00000 - - - CTP_transf_3 HPHIIJEP_02321 224308.BSU37850 3.31e-239 658.0 COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,4HDTP@91061|Bacilli,1ZDRP@1386|Bacillus 91061|Bacilli M Spore Coat spsG - - - - - - - - - - - Glyco_tran_28_C HPHIIJEP_02322 224308.BSU37840 7.45e-178 495.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli,1ZAWH@1386|Bacillus 91061|Bacilli M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis spsI - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase HPHIIJEP_02323 224308.BSU37830 9.08e-234 642.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,1ZBFX@1386|Bacillus 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily spsJ - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd HPHIIJEP_02324 224308.BSU37820 4.72e-204 564.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind HPHIIJEP_02325 224308.BSU37810 7.53e-113 323.0 COG1898@1|root,COG1898@2|Bacteria,1V4G5@1239|Firmicutes,4HGWJ@91061|Bacilli,1ZFSW@1386|Bacillus 91061|Bacilli M Spore Coat spsL - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom HPHIIJEP_02326 1051501.AYTL01000028_gene1986 1.24e-99 290.0 2974U@1|root,2ZUCW@2|Bacteria,1W4BH@1239|Firmicutes,4I1IR@91061|Bacilli,1ZFDP@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02327 224308.BSU37790 8.6e-310 843.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family rocG GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2 ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HPHIIJEP_02328 224308.BSU37780 0.0 1012.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,1ZCI4@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family. RocA subfamily rocA - 1.2.1.88 ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 - R00245,R00707,R00708,R04444,R04445,R05051 RC00080,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000 - - iYO844.BSU37780 Aldedh HPHIIJEP_02329 224308.BSU37770 0.0 1140.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 HPHIIJEP_02330 224308.BSU37760 0.0 899.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,1ZB12@1386|Bacillus 91061|Bacilli E amino acid rocC GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 - ko:K02205,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iYO844.BSU39390 AA_permease HPHIIJEP_02331 224308.BSU37750 6.3e-274 752.0 COG0477@1|root,COG2814@2|Bacteria,1V0Z5@1239|Firmicutes,4HW2N@91061|Bacilli,1ZCZ9@1386|Bacillus 91061|Bacilli EGP -transporter ywfA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_02332 224308.BSU37740 5.11e-146 411.0 COG0077@1|root,COG0077@2|Bacteria,1VY44@1239|Firmicutes,4HXPI@91061|Bacilli,1ZDG1@1386|Bacillus 91061|Bacilli E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate bacA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 4.1.1.100 ko:K19546 ko01130,map01130 M00787 - - ko00000,ko00001,ko00002,ko01000 - - - - HPHIIJEP_02333 224308.BSU37730 1.24e-175 488.0 COG1917@1|root,COG1917@2|Bacteria,1TXB2@1239|Firmicutes,4I68H@91061|Bacilli,1ZEIP@1386|Bacillus 91061|Bacilli S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the bacB GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 ko:K19547 ko01130,map01130 M00787 - - ko00000,ko00001,ko00002,ko01000 - - - Cupin_2 HPHIIJEP_02334 224308.BSU37720 2.58e-177 494.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZEJ9@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) bacC - 1.1.1.385 ko:K19548 ko01130,map01130 M00787 R10917 RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 HPHIIJEP_02335 224308.BSU37710 0.0 936.0 COG0151@1|root,COG0151@2|Bacteria,1VSXT@1239|Firmicutes,4HT21@91061|Bacilli 91061|Bacilli F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide) bacD - 6.3.2.49 ko:K13037 ko01130,map01130 M00787 R11064 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37710 ATP-grasp_4 HPHIIJEP_02336 224308.BSU37700 1.31e-266 732.0 COG0477@1|root,COG2814@2|Bacteria,1UXP5@1239|Firmicutes,4HCSQ@91061|Bacilli,1ZF1Y@1386|Bacillus 91061|Bacilli EGP Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic bacE - - ko:K19552 - - - - ko00000,ko02000 2.A.1.21.5 - - MFS_1,MFS_3 HPHIIJEP_02337 224308.BSU37690 8.63e-295 803.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,1ZEPP@1386|Bacillus 91061|Bacilli E Aminotransferase class I and II ywfG GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 M00034,M00787 R07396,R11068 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_02338 224308.BSU37680 3.93e-175 489.0 COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,1ZBQ2@1386|Bacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase ywfH GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0016999,GO:0017000,GO:0017144,GO:0036094,GO:0044237,GO:0044249,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 - ko:K19550 ko01130,map01130 M00787 R11067 RC03342 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 HPHIIJEP_02339 224308.BSU37670 3.43e-187 519.0 COG3253@1|root,COG3253@2|Bacteria,1TQB2@1239|Firmicutes,4H9YI@91061|Bacilli,1ZAZY@1386|Bacillus 91061|Bacilli C May function as heme-dependent peroxidase ywfI - - ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R11522 RC00884 ko00000,ko00001,ko01000 - - - Chlor_dismutase HPHIIJEP_02340 224308.BSU37660 1.67e-224 619.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,1ZC98@1386|Bacillus 91061|Bacilli C In Salmonella this enzyme is required for ethanolamine catabolism pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB HPHIIJEP_02341 224308.BSU37650 3.73e-209 578.0 COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,1ZBIX@1386|Bacillus 91061|Bacilli K Transcriptional regulator cysL - - ko:K21900 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_02342 224308.BSU37640 1.77e-198 550.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,1ZCIA@1386|Bacillus 91061|Bacilli H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB HPHIIJEP_02343 224308.BSU37630 7.47e-203 562.0 COG0697@1|root,COG0697@2|Bacteria,1TQTG@1239|Firmicutes,4HCMU@91061|Bacilli,1ZCU5@1386|Bacillus 91061|Bacilli EG EamA-like transporter family ywfM - - ko:K03298 - - - - ko00000,ko02000 2.A.7.3 - - EamA HPHIIJEP_02344 224308.BSU37620 5.39e-145 413.0 2A3YB@1|root,30SGP@2|Bacteria,1V3JK@1239|Firmicutes,4HHK1@91061|Bacilli,1ZQRD@1386|Bacillus 91061|Bacilli - - rsfA_1 GO:0005575,GO:0005623,GO:0042763,GO:0044464 - ko:K06314 - - - - ko00000,ko03000 - - - Myb_DNA-bind_6 HPHIIJEP_02345 224308.BSU37610 8.55e-49 155.0 COG4844@1|root,COG4844@2|Bacteria,1VB5Q@1239|Firmicutes,4HKJX@91061|Bacilli,1ZHXV@1386|Bacillus 91061|Bacilli S Belongs to the UPF0741 family ywzC - - - - - - - - - - - DUF1450 HPHIIJEP_02346 224308.BSU37600 0.0 883.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,1ZBRB@1386|Bacillus 91061|Bacilli S COG1078 HD superfamily phosphohydrolases ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD HPHIIJEP_02347 224308.BSU37590 1.47e-115 331.0 COG3465@1|root,COG3465@2|Bacteria,1V6Q4@1239|Firmicutes,4HHX3@91061|Bacilli,1ZFMJ@1386|Bacillus 91061|Bacilli - - ywgA - - ko:K09388 - - - - ko00000 - - - - HPHIIJEP_02348 224308.BSU37580 1.28e-102 297.0 COG1959@1|root,COG1959@2|Bacteria,1V462@1239|Firmicutes,4HHBN@91061|Bacilli,1ZGU4@1386|Bacillus 91061|Bacilli K Transcriptional regulator yffB - - - - - - - - - - - Rrf2 HPHIIJEP_02349 224308.BSU37570 5.54e-303 830.0 COG0477@1|root,COG0477@2|Bacteria,1V2WI@1239|Firmicutes,4HGNH@91061|Bacilli,1ZMH9@1386|Bacillus 91061|Bacilli U Major Facilitator Superfamily mmr GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08166 - - - - ko00000,ko02000 2.A.1.3.10 - - MFS_1 HPHIIJEP_02351 224308.BSU37560 0.0 1268.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZDCN@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD HPHIIJEP_02352 224308.BSU37550 1.76e-94 275.0 COG1846@1|root,COG1846@2|Bacteria,1VBX8@1239|Firmicutes,4HKR1@91061|Bacilli,1ZFE5@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywhA GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_02353 1051501.AYTL01000028_gene2013 1.43e-35 120.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,1ZITA@1386|Bacillus 91061|Bacilli G 4-oxalocrotonate tautomerase dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase HPHIIJEP_02354 224308.BSU37530 3.29e-154 433.0 COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4HK6C@91061|Bacilli,1ZQYX@1386|Bacillus 91061|Bacilli S Peptidase family M50 ywhC - - - - - - - - - - - Peptidase_M50 HPHIIJEP_02355 224308.BSU37520 1.92e-123 351.0 28J0N@1|root,2Z8XT@2|Bacteria,1V1UK@1239|Firmicutes,4HD4W@91061|Bacilli,1ZBQ1@1386|Bacillus 91061|Bacilli S YwhD family ywhD - - - - - - - - - - - YwhD HPHIIJEP_02356 1051501.AYTL01000028_gene2016 2.1e-64 199.0 2C5PG@1|root,310ZM@2|Bacteria,1U3XP@1239|Firmicutes,4IDQ8@91061|Bacilli,1ZJ2U@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02357 224308.BSU37510 0.0 1362.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZBUK@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 ko:K21464 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase HPHIIJEP_02358 224308.BSU37500 1.93e-204 565.0 COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,4H9WU@91061|Bacilli,1ZB0B@1386|Bacillus 91061|Bacilli E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine speE GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37500 Spermine_synt_N,Spermine_synth HPHIIJEP_02359 224308.BSU37490 1.73e-214 591.0 COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,4HA7S@91061|Bacilli,1ZB9A@1386|Bacillus 91061|Bacilli E Belongs to the arginase family speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase HPHIIJEP_02360 224308.BSU37480 4.37e-37 130.0 COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,4HGFP@91061|Bacilli,1ZR2M@1386|Bacillus 91061|Bacilli S Aminoacyl-tRNA editing domain - - - - - - - - - - - - tRNA_edit HPHIIJEP_02362 326423.RBAM_019730 4.08e-100 308.0 COG0457@1|root,COG0457@2|Bacteria,1W0TS@1239|Firmicutes,4HZ05@91061|Bacilli,1ZCCQ@1386|Bacillus 91061|Bacilli S aspartate phosphatase rapA1 - - ko:K06359,ko:K06361 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - TPR_12,TPR_8 HPHIIJEP_02363 224308.BSU37450 1.1e-273 754.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity ywhK - - - - - - - - - - - Phosphoesterase HPHIIJEP_02364 224308.BSU37440 1.18e-315 861.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity ywhL - - - - - - - - - - - Phosphoesterase HPHIIJEP_02366 224308.BSU37420 5.85e-316 859.0 COG0612@1|root,COG0612@2|Bacteria 2|Bacteria L Peptidase, M16 - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C HPHIIJEP_02367 224308.BSU37410 4.18e-277 758.0 COG0612@1|root,COG0612@2|Bacteria 2|Bacteria L Peptidase, M16 - - 2.7.1.26,2.7.7.2 ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01002 - - - Peptidase_M16_C HPHIIJEP_02368 224308.BSU37400 1.39e-296 811.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC mgtA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 ko:K01531,ko:K16905 ko02010,map02010 M00224 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.3.4 - iSF_1195.SF4248 Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase HPHIIJEP_02369 224308.BSU37390 1.5e-169 473.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,1ZCRH@1386|Bacillus 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_02371 224308.BSU37370 0.0 933.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,1ZBK3@1386|Bacillus 91061|Bacilli C Fe-S oxidoreductases - - - ko:K22227 - - - - ko00000 - - - Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM HPHIIJEP_02372 1035184.HMPREF1042_0020 3.71e-12 60.8 2DY3G@1|root,347YK@2|Bacteria,1VZEE@1239|Firmicutes,4HZ9Z@91061|Bacilli,42EF5@671232|Streptococcus anginosus group 91061|Bacilli S Bacteriocin subtilosin A - - - - - - - - - - - - Subtilosin_A HPHIIJEP_02373 224308.BSU37340 4.64e-96 280.0 COG4506@1|root,COG4506@2|Bacteria,1VK4E@1239|Firmicutes,4HR38@91061|Bacilli,1ZHXY@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ywiB - - - - - - - - - - - DUF1934 HPHIIJEP_02374 224308.BSU37330 0.0 1102.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,1ZBP1@1386|Bacillus 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d HPHIIJEP_02375 224308.BSU37320 1.2e-273 750.0 COG2223@1|root,COG2223@2|Bacteria,1TRS9@1239|Firmicutes,4HCY1@91061|Bacilli,1ZBQH@1386|Bacillus 91061|Bacilli P COG2223 Nitrate nitrite transporter narK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - iYO844.BSU37320 MFS_1,PAS_9 HPHIIJEP_02376 224308.BSU37310 3.27e-168 470.0 COG0664@1|root,COG0664@2|Bacteria,1V1UY@1239|Firmicutes,4HFSF@91061|Bacilli,1ZQCG@1386|Bacillus 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein fnr - - - - - - - - - - - HTH_Crp_2,cNMP_binding HPHIIJEP_02377 224308.BSU37300 1.24e-177 494.0 28NT3@1|root,2ZBRV@2|Bacteria,1UPQD@1239|Firmicutes,4IV8Z@91061|Bacilli,1ZSJV@1386|Bacillus 91061|Bacilli S YwiC-like protein ywiC - - - - - - - - - - - YwiC HPHIIJEP_02378 224308.BSU37290 5.02e-110 316.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding arfM - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - cNMP_binding HPHIIJEP_02379 224308.BSU37280 0.0 2529.0 COG5013@1|root,COG5013@2|Bacteria,1TQG1@1239|Firmicutes,4HBVB@91061|Bacilli,1ZC1Z@1386|Bacillus 91061|Bacilli C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family narG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.7.5.1 ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Molybdopterin,Molydop_binding,Nitr_red_alph_N HPHIIJEP_02380 224308.BSU37270 0.0 1020.0 COG1140@1|root,COG1140@2|Bacteria,1TRGG@1239|Firmicutes,4HAR2@91061|Bacilli,1ZCJ2@1386|Bacillus 91061|Bacilli C Nitrate reductase, beta narH - 1.7.5.1 ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530,M00804 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Fer4_11,Nitr_red_bet_C HPHIIJEP_02381 224308.BSU37260 1.13e-121 348.0 COG2180@1|root,COG2180@2|Bacteria,1V4I4@1239|Firmicutes,4HHY3@91061|Bacilli,1ZHHD@1386|Bacillus 91061|Bacilli C nitrate reductase narJ - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - iYO844.BSU37260 Nitrate_red_del HPHIIJEP_02382 224308.BSU37250 1.02e-159 447.0 COG2181@1|root,COG2181@2|Bacteria,1V6BS@1239|Firmicutes,4HTW9@91061|Bacilli,1ZR0N@1386|Bacillus 91061|Bacilli C Nitrate reductase (gamma narI GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363 1.7.5.1 ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 M00529,M00530 R00798,R01106,R09497 RC02812 ko00000,ko00001,ko00002,ko01000 5.A.3.1 - - Nitrate_red_gam HPHIIJEP_02383 224308.BSU37240 0.0 985.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol ywiE GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37240 PLDc_2,PLDc_N HPHIIJEP_02384 224308.BSU37230 0.0 1119.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,1ZBV0@1386|Bacillus 91061|Bacilli V ABC transporter ywjA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_02385 224308.BSU37220 7.8e-124 352.0 COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,4HH71@91061|Bacilli,1ZEDJ@1386|Bacillus 91061|Bacilli H RibD C-terminal domain ywjB - - - - - - - - - - - RibD_C HPHIIJEP_02386 224308.BSU37210 1.32e-57 178.0 29S1C@1|root,30D5T@2|Bacteria,1UAW5@1239|Firmicutes,4IM8Y@91061|Bacilli,1ZJHN@1386|Bacillus 91061|Bacilli - - ywjC - - - - - - - - - - - - HPHIIJEP_02387 224308.BSU37200 2.82e-235 646.0 COG4294@1|root,COG4294@2|Bacteria,1TTCB@1239|Firmicutes,4H9PY@91061|Bacilli,1ZCJ7@1386|Bacillus 91061|Bacilli L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion uvsE - - ko:K13281 - - - - ko00000,ko01000 - - - UvdE HPHIIJEP_02388 1051501.AYTL01000028_gene2047 1.02e-261 720.0 COG1502@1|root,COG1502@2|Bacteria,1USPT@1239|Firmicutes,4HCJD@91061|Bacilli,1ZC77@1386|Bacillus 91061|Bacilli I Belongs to the phospholipase D family. Cardiolipin synthase subfamily clsB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 HPHIIJEP_02389 224308.BSU37180 0.0 1399.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,1ZBAJ@1386|Bacillus 91061|Bacilli C COG0247 Fe-S oxidoreductase ywjF - - - - - - - - - - - CCG,Fer4_8 HPHIIJEP_02390 224308.BSU37170 7.02e-268 734.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase acdA - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HPHIIJEP_02391 224308.BSU37160 1.03e-82 248.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,1ZH95@1386|Bacillus 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH HPHIIJEP_02392 224308.BSU37150 0.0 1073.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,1ZB0S@1386|Bacillus 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase HPHIIJEP_02393 224308.BSU37140 6.41e-118 337.0 COG4821@1|root,COG4821@2|Bacteria,1VJUP@1239|Firmicutes,4HP1J@91061|Bacilli,1ZH7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF2529) ywjG - - - - - - - - - - - DUF2529 HPHIIJEP_02394 1051501.AYTL01000028_gene2053 1.07e-81 242.0 COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HICG@91061|Bacilli,1ZQRZ@1386|Bacillus 91061|Bacilli T COG0784 FOG CheY-like receiver spo0F - - ko:K02490 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg HPHIIJEP_02395 224308.BSU37120 7.82e-204 564.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,1ZBBA@1386|Bacillus 91061|Bacilli G Aldolase fbaA - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase HPHIIJEP_02396 224308.BSU37110 5.69e-147 414.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,4HA8G@91061|Bacilli,1ZCA6@1386|Bacillus 91061|Bacilli G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU37110 TAL_FSA HPHIIJEP_02397 224308.BSU37100 2.26e-303 828.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZASB@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase HPHIIJEP_02398 224308.BSU37090 2.03e-224 619.0 COG1494@1|root,COG1494@2|Bacteria,1TP0D@1239|Firmicutes,4H9MV@91061|Bacilli,1ZC28@1386|Bacillus 91061|Bacilli G fructose-1,6-bisphosphatase glpX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX HPHIIJEP_02399 224308.BSU37080 5.53e-303 827.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,4H9XB@91061|Bacilli,1ZBN9@1386|Bacillus 91061|Bacilli K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind HPHIIJEP_02400 1051501.AYTL01000028_gene2059 7e-45 144.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli,1ZQBD@1386|Bacillus 91061|Bacilli J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 HPHIIJEP_02401 224308.BSU37060 9.96e-135 382.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU37060 TK HPHIIJEP_02402 224308.BSU37050 0.0 1100.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,1ZQEV@1386|Bacillus 91061|Bacilli C malic enzyme ykwA GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic HPHIIJEP_02403 224308.BSU37040 3.24e-204 568.0 COG0679@1|root,COG0679@2|Bacteria,1VDS9@1239|Firmicutes,4HQT5@91061|Bacilli,1ZDDW@1386|Bacillus 91061|Bacilli S Membrane transport protein ywkB - - ko:K07088 - - - - ko00000 - - - Mem_trans HPHIIJEP_02404 224308.BSU37030 2.69e-104 304.0 COG0789@1|root,COG0789@2|Bacteria,1VH5D@1239|Firmicutes,4HQ0J@91061|Bacilli,1ZG6F@1386|Bacillus 91061|Bacilli K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure racA - - ko:K11686 - - - - ko00000,ko03036 - - - MerR_1 HPHIIJEP_02405 224308.BSU37020 4.84e-89 261.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase HPHIIJEP_02406 224308.BSU37010 9.95e-245 673.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,1ZCE9@1386|Bacillus 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 HPHIIJEP_02407 224308.BSU37000 8.46e-205 566.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,1ZBSE@1386|Bacillus 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS HPHIIJEP_02409 224308.BSU36980 2.28e-72 218.0 2B1TR@1|root,31U9Q@2|Bacteria,1UCW8@1239|Firmicutes,4IPC8@91061|Bacilli,1ZPPX@1386|Bacillus 91061|Bacilli S Uncharacterised protein family (UPF0715) ywlA - - - - - - - - - - - UPF0715 HPHIIJEP_02410 224308.BSU36970 1.89e-151 426.0 2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,4HI5F@91061|Bacilli,1ZEE3@1386|Bacillus 91061|Bacilli S stage II sporulation protein R spoIIR - - ko:K06387 - - - - ko00000 - - - Spore_II_R HPHIIJEP_02411 224308.BSU36960 1.79e-100 291.0 COG1246@1|root,COG1246@2|Bacteria,1U9KN@1239|Firmicutes,4IKY0@91061|Bacilli,1ZIA8@1386|Bacillus 91061|Bacilli E Belongs to the acetyltransferase family. ArgA subfamily ywlB - - - - - - - - - - - - HPHIIJEP_02412 224308.BSU36950 1.49e-250 687.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,1ZB2V@1386|Bacillus 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC HPHIIJEP_02413 224308.BSU36940 4.56e-117 336.0 COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,4HH7C@91061|Bacilli,1ZFK0@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp HPHIIJEP_02414 224308.BSU36930 1.58e-100 291.0 COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,1ZH51@1386|Bacillus 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ywlE - 3.1.3.48,3.9.1.2 ko:K01104,ko:K20201 - - - - ko00000,ko01000 - - - LMWPc HPHIIJEP_02415 1051501.AYTL01000028_gene2074 2.35e-106 306.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,1ZFM4@1386|Bacillus 91061|Bacilli G Ribose 5-phosphate isomerase rpiB - 5.3.1.6 ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01056,R09030 RC00376,RC00434 ko00000,ko00001,ko00002,ko01000 - - - LacAB_rpiB HPHIIJEP_02416 224308.BSU36910 2.49e-123 352.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli,1ZFKM@1386|Bacillus 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 HPHIIJEP_02417 224308.BSU36900 1.25e-302 825.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,1ZB9V@1386|Bacillus 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT HPHIIJEP_02418 224308.BSU36890 5.5e-148 416.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,1ZASG@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase HPHIIJEP_02419 224308.BSU36880 1.91e-81 241.0 2E2UM@1|root,32HZ5@2|Bacteria,1V9N6@1239|Firmicutes,4HK0H@91061|Bacilli,1ZQSH@1386|Bacillus 91061|Bacilli S ATP synthase atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATP-synt_I HPHIIJEP_02420 224308.BSU36870 2.47e-166 466.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,1ZB02@1386|Bacillus 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A HPHIIJEP_02421 1051501.AYTL01000028_gene2080 3.01e-36 123.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,1ZIWP@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C HPHIIJEP_02422 224308.BSU36850 2.62e-79 239.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,1ZGHN@1386|Bacillus 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B HPHIIJEP_02423 224308.BSU36840 1.95e-116 334.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP HPHIIJEP_02424 224308.BSU36830 0.0 968.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,1ZB13@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N HPHIIJEP_02425 224308.BSU36820 4.46e-195 542.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,1ZCKT@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt HPHIIJEP_02426 224308.BSU36810 0.0 924.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,1ZB62@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N HPHIIJEP_02427 224308.BSU36800 2.44e-75 226.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,1ZGET@1386|Bacillus 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N HPHIIJEP_02428 224308.BSU36790 1.24e-114 328.0 28YPI@1|root,2ZKH3@2|Bacteria,1W4TC@1239|Firmicutes,4IJT1@91061|Bacilli,1ZE76@1386|Bacillus 91061|Bacilli - - ywmA - - - - - - - - - - - - HPHIIJEP_02429 224308.BSU36780 4.54e-45 145.0 COG4836@1|root,COG4836@2|Bacteria,1VK5C@1239|Firmicutes,4HR8D@91061|Bacilli,1ZJ1E@1386|Bacillus 91061|Bacilli S membrane ywzB - - - - - - - - - - - DUF1146 HPHIIJEP_02430 224308.BSU36770 1.14e-172 482.0 2DSIK@1|root,33GA6@2|Bacteria,1VN6K@1239|Firmicutes,4HSJR@91061|Bacilli,1ZHV5@1386|Bacillus 91061|Bacilli S TATA-box binding ywmB - - - - - - - - - - - DUF1779 HPHIIJEP_02431 224308.BSU36760 4.96e-306 835.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,1ZB89@1386|Bacillus 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase HPHIIJEP_02432 224308.BSU36750 9.77e-234 644.0 COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,4HCE3@91061|Bacilli,1ZBNU@1386|Bacillus 91061|Bacilli D Stage II sporulation protein D spoIID GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K06381 - - - - ko00000 - - - SpoIID HPHIIJEP_02433 224308.BSU36740 1.89e-157 442.0 COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,1ZD9C@1386|Bacillus 91061|Bacilli S protein containing a von Willebrand factor type A (vWA) domain ywmC - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA HPHIIJEP_02434 224308.BSU36730 1.02e-155 437.0 COG2304@1|root,COG2304@2|Bacteria,1UZKX@1239|Firmicutes,4HCSC@91061|Bacilli,1ZBWZ@1386|Bacillus 91061|Bacilli S protein containing a von Willebrand factor type A (vWA) domain ywmD - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA HPHIIJEP_02436 224308.BSU36710 5.24e-186 517.0 COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus 91061|Bacilli C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ HPHIIJEP_02437 224308.BSU36700 1.79e-244 671.0 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,1ZCD4@1386|Bacillus 91061|Bacilli H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM HPHIIJEP_02438 1051501.AYTL01000027_gene816 1.54e-129 383.0 COG0457@1|root,COG0457@2|Bacteria,1UUXQ@1239|Firmicutes,4I402@91061|Bacilli,1ZDKN@1386|Bacillus 91061|Bacilli S Response regulator aspartate phosphatase rapA - - ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 - - - ko00000,ko00001,ko01000 - - - TPR_12,TPR_16 HPHIIJEP_02439 224308.BSU36680 1.53e-109 317.0 COG1994@1|root,COG1994@2|Bacteria,1V8QC@1239|Firmicutes,4HK02@91061|Bacilli,1ZQQW@1386|Bacillus 91061|Bacilli S Peptidase M50 ywmF - - - - - - - - - - - Peptidase_M50 HPHIIJEP_02440 224308.BSU36670 1.51e-19 80.5 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like csbD - - - - - - - - - - - CsbD HPHIIJEP_02441 1051501.AYTL01000028_gene2105 6.86e-29 110.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZBFK@1386|Bacillus 91061|Bacilli E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran HPHIIJEP_02442 224308.BSU36660 8.2e-68 205.0 COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli,1ZH3M@1386|Bacillus 91061|Bacilli E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iSB619.SA_RS11965,iYO844.BSU36660 Urease_gamma HPHIIJEP_02443 224308.BSU36650 1.12e-83 247.0 COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli,1ZH2P@1386|Bacillus 91061|Bacilli E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta HPHIIJEP_02444 224308.BSU36640 0.0 1131.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli,1ZDMR@1386|Bacillus 91061|Bacilli E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha HPHIIJEP_02445 224308.BSU36630 4.58e-85 251.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli,1ZHA4@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywnA - - - - - - - - - - - Rrf2 HPHIIJEP_02446 224308.BSU36620 1.24e-146 413.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HAJ4@91061|Bacilli,1ZESA@1386|Bacillus 91061|Bacilli S NAD(P)H-binding ywnB - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 HPHIIJEP_02447 224308.BSU36610 1.24e-77 232.0 2EKMP@1|root,33EBE@2|Bacteria,1VQNN@1239|Firmicutes,4HSNG@91061|Bacilli,1ZG44@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5362) ywnC - - - - - - - - - - - DUF5362 HPHIIJEP_02448 224308.BSU36600 5e-177 494.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,1ZBMT@1386|Bacillus 91061|Bacilli K transcriptional mta - - ko:K21743 - - - - ko00000,ko03000 - - - MerR_1,TipAS HPHIIJEP_02449 326423.RBAM_020310 1.97e-31 116.0 28U06@1|root,2ZSTF@2|Bacteria,1W475@1239|Firmicutes,4I0TG@91061|Bacilli 91061|Bacilli - - yqgA - - - - - - - - - - - - HPHIIJEP_02450 224308.BSU36590 0.0 957.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,1ZBG7@1386|Bacillus 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol ywnE GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0032502,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N HPHIIJEP_02451 224308.BSU36580 7.07e-92 269.0 2E4P1@1|root,32ZHT@2|Bacteria,1VF8Y@1239|Firmicutes,4HQ3Y@91061|Bacilli,1ZJ57@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5392) ywnF - - - - - - - - - - - DUF5392 HPHIIJEP_02452 720555.BATR1942_16260 2.32e-22 94.0 2EKMP@1|root,33EBE@2|Bacteria,1VQNN@1239|Firmicutes,4HSNG@91061|Bacilli,1ZG44@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5362) ywnC - - - - - - - - - - - DUF5362 HPHIIJEP_02453 224308.BSU36560 1.49e-114 328.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,1ZFR7@1386|Bacillus 91061|Bacilli M COG1247 Sortase and related acyltransferases ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 HPHIIJEP_02454 1051501.AYTL01000028_gene2123 1.85e-161 457.0 COG0739@1|root,COG0739@2|Bacteria,1V7CU@1239|Firmicutes,4HCZJ@91061|Bacilli,1ZC61@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIIQ GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - ko:K06386 - - - - ko00000 1.A.34.1.1 - - Peptidase_M23 HPHIIJEP_02455 224308.BSU36540 1.63e-95 278.0 2E5BV@1|root,3303W@2|Bacteria,1VGUK@1239|Firmicutes,4HQU7@91061|Bacilli,1ZHPH@1386|Bacillus 91061|Bacilli S VanZ like family ywnJ - - - - - - - - - - - VanZ HPHIIJEP_02456 224308.BSU36530 6.02e-135 382.0 COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HN1F@91061|Bacilli,1ZGFZ@1386|Bacillus 91061|Bacilli I COG0671 Membrane-associated phospholipid phosphatase bcrC - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 HPHIIJEP_02457 224308.BSU36520 4.51e-77 229.0 COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HM5G@91061|Bacilli,1ZGHT@1386|Bacillus 91061|Bacilli K Belongs to the P(II) protein family nrgB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II HPHIIJEP_02458 224308.BSU36510 1.6e-288 788.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,1ZB5S@1386|Bacillus 91061|Bacilli P Ammonium transporter nrgA - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - iYO844.BSU36510 Ammonium_transp HPHIIJEP_02459 224308.BSU36500 5.04e-101 293.0 2CDZ7@1|root,310W6@2|Bacteria,1VY2S@1239|Firmicutes,4HWZM@91061|Bacilli,1ZGUV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02460 224308.BSU36490 1.48e-133 378.0 COG1335@1|root,COG1335@2|Bacteria,1V4UN@1239|Firmicutes,4HH38@91061|Bacilli,1ZG0P@1386|Bacillus 91061|Bacilli Q Isochorismatase family yjgF - - - - - - - - - - - Isochorismatase HPHIIJEP_02461 224308.BSU36480 1.09e-306 838.0 COG0477@1|root,COG0477@2|Bacteria,1UIYG@1239|Firmicutes,4ISX7@91061|Bacilli,1ZAWC@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily ywoD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_02462 224308.BSU36470 0.0 967.0 COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,4HAIM@91061|Bacilli,1ZDNH@1386|Bacillus 91061|Bacilli FH COG1953 Cytosine uracil thiamine allantoin permeases - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K03457,ko:K10975 - - - - ko00000,ko02000 2.A.39,2.A.39.3.8 - - Transp_cyt_pur HPHIIJEP_02463 224308.BSU36460 1.19e-311 852.0 COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,1ZDPG@1386|Bacillus 91061|Bacilli P Right handed beta helix region ywoF - - - - - - - - - - - Beta_helix,DUF1565 HPHIIJEP_02464 224308.BSU36450 1.37e-269 739.0 COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,1ZAUW@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily ywoG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,MFS_2,Sugar_tr HPHIIJEP_02465 224308.BSU36440 8.45e-92 268.0 COG1846@1|root,COG1846@2|Bacteria,1VBQ1@1239|Firmicutes,4HMXC@91061|Bacilli,1ZIKI@1386|Bacillus 91061|Bacilli K COG1846 Transcriptional regulators - - - - - - - - - - - - HTH_27,MarR,MarR_2 HPHIIJEP_02466 224308.BSU36420 4.88e-59 182.0 COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,4HKIY@91061|Bacilli,1ZGY1@1386|Bacillus 91061|Bacilli K Stage III sporulation protein D spoIIID - - ko:K06283 - - - - ko00000,ko03000 - - - SpoIIID HPHIIJEP_02467 224308.BSU36410 1.75e-231 638.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZC87@1386|Bacillus 91061|Bacilli D Rod shape-determining protein mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl HPHIIJEP_02468 224308.BSU36400 1.77e-172 483.0 COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,4HCKG@91061|Bacilli,1ZBEC@1386|Bacillus 91061|Bacilli N flagellar basal body flhO GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C HPHIIJEP_02469 224308.BSU36390 1.17e-181 506.0 COG4786@1|root,COG4786@2|Bacteria,1TSYY@1239|Firmicutes,4HC6B@91061|Bacilli,1ZCIJ@1386|Bacillus 91061|Bacilli N flagellar basal body flhP GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C HPHIIJEP_02470 224308.BSU36380 3.52e-253 694.0 COG0457@1|root,COG0457@2|Bacteria,1U3RZ@1239|Firmicutes,4IDJ0@91061|Bacilli,1ZF5Q@1386|Bacillus 91061|Bacilli S aspartate phosphatase rapD - - ko:K06362 - - - - ko00000,ko01000 - - - TPR_12 HPHIIJEP_02471 1051501.AYTL01000028_gene2141 6.89e-107 308.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,1ZFJ9@1386|Bacillus 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA HPHIIJEP_02472 224308.BSU36360 1.32e-78 234.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,1ZH44@1386|Bacillus 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL HPHIIJEP_02473 1051501.AYTL01000028_gene2143 0.0 1817.0 COG0642@1|root,COG0745@1|root,COG2972@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2972@2|Bacteria,1TRIG@1239|Firmicutes,4HD8X@91061|Bacilli,1ZS5Y@1386|Bacillus 91061|Bacilli T Histidine kinase ywpD - - - - - - - - - - - 7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg HPHIIJEP_02474 1051501.AYTL01000028_gene2144 1.68e-221 615.0 COG3947@1|root,COG3947@2|Bacteria,1V85E@1239|Firmicutes,4HGJR@91061|Bacilli,1ZG1V@1386|Bacillus 91061|Bacilli T Transcriptional regulatory protein, C terminal M1-574 - - - - - - - - - - - BTAD,Response_reg,Trans_reg_C HPHIIJEP_02475 1051501.AYTL01000028_gene2145 0.0 3236.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus 91061|Bacilli M cell wall anchor domain - - - - - - - - - - - - Collagen_bind,Gram_pos_anchor HPHIIJEP_02476 1051501.AYTL01000028_gene2146 5.85e-107 313.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,1ZRFS@1386|Bacillus 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase HPHIIJEP_02477 224308.BSU36330 8.81e-89 261.0 2E3V2@1|root,32YSB@2|Bacteria,1V8K8@1239|Firmicutes,4HMGU@91061|Bacilli,1ZEV0@1386|Bacillus 91061|Bacilli S YwpF-like protein ywpF - - - - - - - - - - - YwpF HPHIIJEP_02478 224308.BSU36320 5.26e-88 258.0 29RI2@1|root,30CM1@2|Bacteria,1UA2P@1239|Firmicutes,4IKC3@91061|Bacilli,1ZGE4@1386|Bacillus 91061|Bacilli - - ywpG - - - - - - - - - - - - HPHIIJEP_02479 224308.BSU36310 8.53e-76 226.0 COG0629@1|root,COG0629@2|Bacteria,1V797@1239|Firmicutes,4HJFJ@91061|Bacilli,1ZH3N@1386|Bacillus 91061|Bacilli L Single-stranded DNA-binding protein ssbB - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB HPHIIJEP_02480 224308.BSU36300 1.96e-179 500.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,1ZEDB@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism glcR - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR HPHIIJEP_02481 224308.BSU36290 4.34e-201 557.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ywpJ - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 HPHIIJEP_02482 224308.BSU36280 0.0 1843.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli,1ZBZT@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family ywqA - - - - - - - - - - - DUF3670,Helicase_C,SNF2_N HPHIIJEP_02483 224308.BSU36270 0.0 1056.0 COG4715@1|root,COG4715@2|Bacteria,1TSUG@1239|Firmicutes,4HBPY@91061|Bacilli,1ZR5V@1386|Bacillus 91061|Bacilli S SWIM zinc finger ywqB - - - - - - - - - - - SWIM HPHIIJEP_02484 224308.BSU36269 3.6e-25 93.6 2BF9J@1|root,3292F@2|Bacteria,1UBE9@1239|Firmicutes,4IMSZ@91061|Bacilli,1ZKRV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02485 224308.BSU36260 5.33e-163 457.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus 91061|Bacilli M biosynthesis protein ywqC - - ko:K19420 - - - - ko00000 - - - GNVR,Wzz HPHIIJEP_02486 224308.BSU36250 1.06e-152 430.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1ZB83@1386|Bacillus 91061|Bacilli D COG0489 ATPases involved in chromosome partitioning ywqD - 2.7.10.2 ko:K00903 - - - - ko00000,ko01000,ko01001 - - - AAA_31,CbiA,ParA HPHIIJEP_02487 224308.BSU36240 1.44e-179 500.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,1ZDH3@1386|Bacillus 91061|Bacilli GM COG4464 Capsular polysaccharide biosynthesis protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - HPHIIJEP_02488 224308.BSU36230 4.66e-313 853.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ywqF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N HPHIIJEP_02489 224308.BSU36220 8.46e-196 541.0 COG3878@1|root,COG3878@2|Bacteria,1V7GE@1239|Firmicutes,4HJ4G@91061|Bacilli,1ZF4W@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1963) ywqG - - - - - - - - - - - DUF1963 HPHIIJEP_02491 224308.BSU36200 2.17e-52 165.0 2ENUM@1|root,33GFQ@2|Bacteria,1VKUV@1239|Firmicutes,4HR78@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF5344) ywqI - - - - - - - - - - - DUF5344 HPHIIJEP_02492 720555.BATR1942_16015 2.89e-302 840.0 COG4104@1|root,COG5444@1|root,COG4104@2|Bacteria,COG5444@2|Bacteria,1UJ8U@1239|Firmicutes,4HKX1@91061|Bacilli,1ZQPF@1386|Bacillus 91061|Bacilli S Pre-toxin TG ywqJ - - - - - - - - - - - LXG,PT-TG HPHIIJEP_02494 224308.BSU36170 1.77e-149 422.0 COG1515@1|root,COG1515@2|Bacteria,1V1CJ@1239|Firmicutes,4HEAW@91061|Bacilli,1ZBJQ@1386|Bacillus 91061|Bacilli L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA nfi - 3.1.21.7 ko:K05982 - - - - ko00000,ko01000,ko03400 - - - Endonuclease_5 HPHIIJEP_02496 224308.BSU36130 6.07e-114 328.0 COG2059@1|root,COG2059@2|Bacteria,1V2C2@1239|Firmicutes,4HFTN@91061|Bacilli,1ZR6K@1386|Bacillus 91061|Bacilli P COG2059 Chromate transport protein ChrA ywrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp HPHIIJEP_02497 224308.BSU36120 6.44e-132 375.0 COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,4IQZD@91061|Bacilli,1ZRPT@1386|Bacillus 91061|Bacilli P Chromate transporter ywrB - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - iYO844.BSU36120 Chromate_transp HPHIIJEP_02498 224308.BSU36110 2.79e-107 309.0 COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,4HFRT@91061|Bacilli,1ZG22@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywrC GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type HPHIIJEP_02499 224308.BSU36100 0.0 1055.0 COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus 91061|Bacilli E gamma-glutamyltransferase ywrD - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept HPHIIJEP_02500 224308.BSU36090 3.02e-69 209.0 29SDM@1|root,30DIC@2|Bacteria,1UBBF@1239|Firmicutes,4IMQD@91061|Bacilli,1ZKM0@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF4181) - - - - - - - - - - - - DUF4181 HPHIIJEP_02501 224308.BSU36080 1.03e-141 400.0 COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,1ZB1C@1386|Bacillus 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family ywrF - - - - - - - - - - - Flavin_Reduct HPHIIJEP_02502 720555.BATR1942_15925 1e-17 84.0 29SRG@1|root,30DXD@2|Bacteria,1UBV7@1239|Firmicutes,4INAQ@91061|Bacilli,1ZN5C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02503 224308.BSU36060 2.08e-265 726.0 COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus 91061|Bacilli M Spore Coat cotH - - ko:K06330 - - - - ko00000 - - - CotH HPHIIJEP_02504 224308.BSU36050 1.99e-171 490.0 2E48W@1|root,32Z4Q@2|Bacteria,1VF41@1239|Firmicutes,4HPBF@91061|Bacilli,1ZGKF@1386|Bacillus 91061|Bacilli - - cotB - - ko:K06325 - - - - ko00000 - - - - HPHIIJEP_02505 224308.BSU36040 2.14e-162 454.0 29H6Z@1|root,3044I@2|Bacteria,1V4SZ@1239|Firmicutes,4HHCE@91061|Bacilli,1ZFWE@1386|Bacillus 91061|Bacilli - - ywrJ - - - - - - - - - - - - HPHIIJEP_02506 224308.BSU36030 1.32e-278 764.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H9WV@91061|Bacilli,1ZBHC@1386|Bacillus 91061|Bacilli P Involved in arsenical resistance. Thought to form the channel of an arsenite pump ywrK - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - ArsB HPHIIJEP_02507 224308.BSU36020 3.36e-218 602.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HHXD@91061|Bacilli,1ZRMJ@1386|Bacillus 91061|Bacilli K LysR substrate binding domain alsR - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_02508 224308.BSU36010 0.0 1115.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,1ZE8P@1386|Bacillus 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HPHIIJEP_02509 224308.BSU36000 1.84e-187 520.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HHNB@91061|Bacilli,1ZQAI@1386|Bacillus 91061|Bacilli H Alpha-acetolactate decarboxylase budA GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy HPHIIJEP_02510 224308.BSU35990 3.57e-125 356.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HH6R@91061|Bacilli,1ZGJ6@1386|Bacillus 91061|Bacilli S NADPH-quinone reductase (modulator of drug activity B) ywrO - - - - - - - - - - - Flavodoxin_2 HPHIIJEP_02511 224308.BSU35980 3.75e-63 193.0 2E59K@1|root,3301W@2|Bacteria,1VF4H@1239|Firmicutes,4HPY9@91061|Bacilli,1ZQTK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3892) ywsA - - - - - - - - - - - DUF3892 HPHIIJEP_02512 224308.BSU35970 4.83e-120 343.0 COG3103@1|root,COG3103@2|Bacteria 2|Bacteria T Sh3 type 3 domain protein batE - - - - - - - - - - - BatD,Phenol_MetA_deg,SH3_3,SH3_4,TPR_16,TPR_2 HPHIIJEP_02513 224308.BSU35960 9.04e-204 565.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,1ZD3D@1386|Bacillus 91061|Bacilli G COG1879 ABC-type sugar transport system, periplasmic component rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 HPHIIJEP_02514 224308.BSU35950 3.35e-203 565.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,1ZBAZ@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 HPHIIJEP_02515 224308.BSU35940 0.0 949.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran HPHIIJEP_02516 224308.BSU35930 6.55e-84 248.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,1ZGYM@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU HPHIIJEP_02517 224308.BSU35920 1.25e-204 566.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HA87@91061|Bacilli,1ZCQ4@1386|Bacillus 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB HPHIIJEP_02518 224308.BSU35910 2.68e-227 627.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli,1ZC3W@1386|Bacillus 91061|Bacilli K transcriptional rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_02519 224308.BSU35900 1.46e-283 775.0 COG0771@1|root,COG0771@2|Bacteria,1U01Y@1239|Firmicutes,4HDCH@91061|Bacilli,1ZDU1@1386|Bacillus 91061|Bacilli M COG0769 UDP-N-acetylmuramyl tripeptide synthase capB - - ko:K01932 - - - - ko00000,ko01000 - - - Mur_ligase_M HPHIIJEP_02520 224308.BSU35890 8.44e-91 267.0 29EG8@1|root,301E5@2|Bacteria,1V445@1239|Firmicutes,4HHXZ@91061|Bacilli,1ZGKP@1386|Bacillus 91061|Bacilli S biosynthesis protein capC - - ko:K22116 - - - - ko00000 - - - Caps_synth_CapC HPHIIJEP_02521 224308.BSU35880 1.1e-276 756.0 COG2843@1|root,COG2843@2|Bacteria,1TSQG@1239|Firmicutes,4HCUP@91061|Bacilli,1ZQDC@1386|Bacillus 91061|Bacilli M enzyme of poly-gamma-glutamate biosynthesis (capsule formation) capA - - ko:K07282 - - - - ko00000 - - - PGA_cap HPHIIJEP_02522 224308.BSU35870 2.29e-29 104.0 29QU5@1|root,30BU5@2|Bacteria,1U8NV@1239|Firmicutes,4IIKX@91061|Bacilli,1ZNS6@1386|Bacillus 91061|Bacilli - - ywtC - - - - - - - - - - - - HPHIIJEP_02523 224308.BSU35860 1.37e-304 831.0 COG0791@1|root,COG0791@2|Bacteria,1V7MV@1239|Firmicutes,4HCQ2@91061|Bacilli,1ZBTD@1386|Bacillus 91061|Bacilli M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) pgdS GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - Cu_amine_oxidN1,NLPC_P60 HPHIIJEP_02524 224308.BSU35850 7.24e-205 566.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,1ZDBI@1386|Bacillus 91061|Bacilli S hydrolases of the HAD superfamily ywtE - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 HPHIIJEP_02525 224308.BSU35840 1.42e-220 609.0 COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus 91061|Bacilli K Transcriptional regulator ywtF_2 - - - - - - - - - - - LytR_cpsA_psr HPHIIJEP_02526 224308.BSU35830 2.14e-313 855.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,1ZAUM@1386|Bacillus 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family ywtG GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.26 - - Sugar_tr HPHIIJEP_02527 224308.BSU35820 2.48e-254 699.0 28IEM@1|root,2Z8GN@2|Bacteria,1UB3Y@1239|Firmicutes,4HV0B@91061|Bacilli,1ZRWJ@1386|Bacillus 91061|Bacilli S Spore germination protein gerBC - - ko:K06290,ko:K06293,ko:K06312 - - - - ko00000 - - - Spore_GerAC HPHIIJEP_02528 224308.BSU35810 2.1e-248 684.0 COG0814@1|root,COG0814@2|Bacteria,1UI6P@1239|Firmicutes,4ISFP@91061|Bacilli,1ZDSE@1386|Bacillus 91061|Bacilli E Spore germination protein gerAB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06289,ko:K06292 - - - - ko00000,ko02000 2.A.3.9.1,2.A.3.9.2 - - Spore_permease HPHIIJEP_02529 224308.BSU35800 0.0 914.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerBA - - ko:K06288,ko:K06291,ko:K06310 - - - - ko00000 - - - GerA HPHIIJEP_02530 224308.BSU35790 6.17e-237 650.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,1ZDJI@1386|Bacillus 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI HPHIIJEP_02531 224308.BSU35780 0.0 947.0 COG4193@1|root,COG4193@2|Bacteria,1V1F9@1239|Firmicutes,4HWI1@91061|Bacilli,1ZRF0@1386|Bacillus 91061|Bacilli G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase lytD - 3.2.1.96 ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,PA14,SH3_3,SPOR HPHIIJEP_02532 1408303.JNJJ01000004_gene823 1.42e-235 672.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HCMW@91061|Bacilli,1ZPWY@1386|Bacillus 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tarL - 2.7.8.14,2.7.8.47 ko:K18704 - - R11614,R11621 - ko00000,ko01000 - - - Glyphos_transf HPHIIJEP_02533 171693.BN988_03551 4.73e-110 334.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HBRD@91061|Bacilli 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase tarK - 2.7.8.14,2.7.8.46,2.7.8.47 ko:K18704,ko:K21592 - - R11613,R11614,R11621 - ko00000,ko01000 - - - Glycos_transf_2,Glyphos_transf HPHIIJEP_02534 1347086.CCBA010000004_gene4232 5.68e-186 523.0 COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,4HCCH@91061|Bacilli,1ZDNN@1386|Bacillus 91061|Bacilli E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate tarJ - 1.1.1.137,1.1.1.405 ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 - R01524,R01525 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,Glu_dehyd_C HPHIIJEP_02535 1347086.CCBA010000004_gene4233 1.46e-134 385.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HFH7@91061|Bacilli,1ZE75@1386|Bacillus 91061|Bacilli I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate tarI GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.40,2.7.7.60 ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R02921,R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD HPHIIJEP_02536 326423.RBAM_032890 5.44e-117 350.0 COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,4HBID@91061|Bacilli,1ZCUZ@1386|Bacillus 91061|Bacilli M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC tagB - 2.7.8.44 ko:K21285 - - R11558 RC00078 ko00000,ko01000 - - iYO844.BSU35760 Glyphos_transf HPHIIJEP_02537 279010.BL02432 1.37e-110 326.0 COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,4HH6B@91061|Bacilli,1ZFMX@1386|Bacillus 91061|Bacilli M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid tagA - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB HPHIIJEP_02538 279010.BL02464 1.32e-73 222.0 COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,4HGWZ@91061|Bacilli,1ZGEJ@1386|Bacillus 91061|Bacilli IM Cytidylyltransferase tagD - 2.7.7.39 ko:K00980 ko00564,map00564 - R00856 RC00002 ko00000,ko00001,ko01000 - - - CTP_transf_like HPHIIJEP_02539 279010.BL02463 1.79e-166 490.0 COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,4H9Q1@91061|Bacilli,1ZB61@1386|Bacillus 91061|Bacilli M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC tagF GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016740,GO:0016757,GO:0044464,GO:0071944 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glyphos_transf HPHIIJEP_02540 224308.BSU35690 8.32e-134 400.0 COG0463@1|root,COG0463@2|Bacteria,1V35I@1239|Firmicutes,4HG1U@91061|Bacilli,1ZAYQ@1386|Bacillus 91061|Bacilli M Glycosyltransferase like family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02541 315750.BPUM_2919 1.49e-102 335.0 2A2YD@1|root,30RCT@2|Bacteria,1V584@1239|Firmicutes,4HHHC@91061|Bacilli,1ZQSU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02542 574375.BAGA_12625 6.73e-165 474.0 COG1215@1|root,COG1215@2|Bacteria,1VRNG@1239|Firmicutes,4HV0M@91061|Bacilli,1ZPWG@1386|Bacillus 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02543 545693.BMQ_1136 5.53e-179 534.0 COG1887@1|root,COG1887@2|Bacteria,1VTRP@1239|Firmicutes,4HUVX@91061|Bacilli,1ZBWP@1386|Bacillus 91061|Bacilli M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - - - - - - - - - - Glyphos_transf HPHIIJEP_02544 224308.BSU35710 1.95e-167 471.0 COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,4HB9R@91061|Bacilli,1ZC4D@1386|Bacillus 91061|Bacilli GM Transport permease protein tagG GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0033036,GO:0051179,GO:0051234,GO:0071702,GO:1901264 - ko:K09692 ko02010,map02010 M00251 - - ko00000,ko00001,ko00002,ko02000 3.A.1.104 - - ABC2_membrane HPHIIJEP_02545 224308.BSU35700 0.0 999.0 COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,1ZC6D@1386|Bacillus 91061|Bacilli GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system tagH GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505 3.6.3.40 ko:K09693 ko02010,map02010 M00251 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.104 - - ABC_tran,LysM HPHIIJEP_02546 224308.BSU35670 2.74e-208 576.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase gtaB - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase HPHIIJEP_02548 1227360.C176_03428 1.22e-118 365.0 COG0438@1|root,COG0438@2|Bacteria,1V09I@1239|Firmicutes,4HG82@91061|Bacilli,26H4R@186818|Planococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_A_1,Glycos_transf_1 HPHIIJEP_02549 1159488.SEQMU2_10260 1.48e-103 333.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4IS4U@91061|Bacilli,4GXTV@90964|Staphylococcaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02550 224308.BSU35660 3.14e-276 755.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli,1ZCZG@1386|Bacillus 91061|Bacilli M Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 HPHIIJEP_02551 224308.BSU35650 1.16e-211 585.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,1ZBT5@1386|Bacillus 91061|Bacilli K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG) lytR - - - - - - - - - - - LytR_cpsA_psr HPHIIJEP_02552 1178540.BA70_11210 9.07e-16 76.3 2E29G@1|root,32XF4@2|Bacteria,1UAW3@1239|Firmicutes,4IM8W@91061|Bacilli,1ZJHI@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02553 279010.BL03347 0.0 1117.0 COG2247@1|root,COG2385@1|root,COG2247@2|Bacteria,COG2385@2|Bacteria,1V9XE@1239|Firmicutes,4HDNT@91061|Bacilli,1ZF67@1386|Bacillus 91061|Bacilli D Stage II sporulation protein lytB GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - - - - - - - - - - CW_binding_2,PG_binding_1,SH3_3,SpoIID HPHIIJEP_02554 279010.BL03348 5.81e-261 726.0 COG0860@1|root,COG2247@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZD0F@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase lytC GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,CW_binding_2,Cu_amine_oxidN1,GBS_Bsp-like,PG_binding_1,SH3_3,SLH HPHIIJEP_02555 1280.SAXN108_0238 1.78e-108 345.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4IS4U@91061|Bacilli,4GXTV@90964|Staphylococcaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 HPHIIJEP_02556 1051501.AYTL01000004_gene3401 1.49e-143 406.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,1ZDDY@1386|Bacillus 91061|Bacilli M COG2148 Sugar transferases involved in lipopolysaccharide synthesis tuaA - - - - - - - - - - - Bac_transf HPHIIJEP_02557 224308.BSU35600 1.03e-315 863.0 COG2244@1|root,COG2244@2|Bacteria,1TPSH@1239|Firmicutes,4HAGX@91061|Bacilli,1ZDDM@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid tuaB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328,ko:K16694,ko:K16695 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.6,2.A.66.2.7 - iYO844.BSU35600 Polysacc_synt_3,Polysacc_synt_C HPHIIJEP_02558 224308.BSU35590 5.92e-281 768.0 COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4ISX6@91061|Bacilli,1ZS7S@1386|Bacillus 91061|Bacilli GM Teichuronic acid tuaC GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16697 - - - - ko00000,ko01000,ko01003 - GT4 iYO844.BSU35590 Glyco_transf_4,Glycos_transf_1 HPHIIJEP_02559 224308.BSU35580 0.0 895.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family tuaD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N HPHIIJEP_02560 224308.BSU35570 0.0 913.0 COG3307@1|root,COG3307@2|Bacteria,1V5WV@1239|Firmicutes,4HF4U@91061|Bacilli,1ZC1E@1386|Bacillus 91061|Bacilli M Teichuronic acid biosynthesis protein tuaE - - ko:K16705 - - - - ko00000 - - - Wzy_C HPHIIJEP_02561 224308.BSU35560 5.79e-147 415.0 COG3206@1|root,COG3206@2|Bacteria,1VMAJ@1239|Firmicutes,4HRWH@91061|Bacilli,1ZET2@1386|Bacillus 91061|Bacilli M protein involved in exopolysaccharide biosynthesis tuaF - - ko:K16706 - - - - ko00000 - - - Wzz HPHIIJEP_02562 224308.BSU35550 8.42e-187 518.0 COG1215@1|root,COG1215@2|Bacteria,1VUUB@1239|Firmicutes,4IS9M@91061|Bacilli,1ZCPM@1386|Bacillus 91061|Bacilli M Glycosyltransferase like family 2 tuaG GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16698 - - - - ko00000,ko01000,ko01003 - GT2 iYO844.BSU35550 Glycos_transf_2 HPHIIJEP_02563 224308.BSU35540 7.15e-298 811.0 COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,4HP9Q@91061|Bacilli,1ZBVC@1386|Bacillus 91061|Bacilli M Teichuronic acid biosynthesis glycosyltransferase tuaH tuaH GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K16699 - - - - ko00000,ko01000,ko01003 - - - Glyco_trans_1_4 HPHIIJEP_02564 224308.BSU35530 2.1e-231 640.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli,1ZBZB@1386|Bacillus 91061|Bacilli M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 HPHIIJEP_02565 224308.BSU35520 2.38e-223 622.0 COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvhJ - - - - - - - - - - - LytR_cpsA_psr HPHIIJEP_02566 224308.BSU35510 2.41e-155 436.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,1ZAXD@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1949) yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 HPHIIJEP_02567 224308.BSU35500 2.94e-247 682.0 COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,4HAUU@91061|Bacilli,1ZDAA@1386|Bacillus 91061|Bacilli T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase degS - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 HPHIIJEP_02568 224308.BSU35490 7.16e-163 456.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,1ZB23@1386|Bacillus 91061|Bacilli KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain degU - - ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 M00478 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_02569 224308.BSU35480 2.15e-199 552.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,1ZAQH@1386|Bacillus 91061|Bacilli S protein conserved in bacteria degV - - - - - - - - - - - DegV HPHIIJEP_02570 224308.BSU35470 0.0 925.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,1ZBXC@1386|Bacillus 91061|Bacilli L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII HPHIIJEP_02571 224308.BSU35460 1.26e-61 189.0 2DNY2@1|root,32ZR4@2|Bacteria,1VEGZ@1239|Firmicutes,4HQDM@91061|Bacilli,1ZHFM@1386|Bacillus 91061|Bacilli S Late competence development protein ComFB comFB - - ko:K02241 - M00429 - - ko00000,ko00002,ko02044 - - - ComFB HPHIIJEP_02572 224308.BSU35450 2.26e-162 455.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,1ZG88@1386|Bacillus 91061|Bacilli S Phosphoribosyl transferase domain comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran HPHIIJEP_02573 224308.BSU35440 1.83e-96 280.0 2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,4HKIR@91061|Bacilli,1ZIAM@1386|Bacillus 91061|Bacilli S flagellar protein yvyF - - - - - - - - - - - - HPHIIJEP_02574 224308.BSU35430 8.4e-51 161.0 COG2747@1|root,COG2747@2|Bacteria,1VKHM@1239|Firmicutes,4HRCG@91061|Bacilli,1ZIVP@1386|Bacillus 91061|Bacilli KNU Negative regulator of flagellin synthesis flgM - - ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 - - - ko00000,ko00001,ko02035 - - - FlgM HPHIIJEP_02575 224308.BSU35420 3.5e-102 296.0 COG3418@1|root,COG3418@2|Bacteria,1VF67@1239|Firmicutes,4HMI4@91061|Bacilli,1ZJCA@1386|Bacillus 91061|Bacilli NOU FlgN protein yvyG - - - - - - - - - - - FlgN HPHIIJEP_02576 224308.BSU35410 0.0 953.0 COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1TPXH@1239|Firmicutes,4HAKM@91061|Bacilli,1ZB70@1386|Bacillus 91061|Bacilli N flagellar hook-associated protein flgK - - ko:K02396 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C HPHIIJEP_02577 224308.BSU35400 7.66e-197 547.0 COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4HCCZ@91061|Bacilli,1ZC4T@1386|Bacillus 91061|Bacilli N Belongs to the bacterial flagellin family flgL GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02397 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N HPHIIJEP_02578 224308.BSU35390 6.92e-92 273.0 2AZFG@1|root,31RPF@2|Bacteria,1VDGT@1239|Firmicutes,4HMCF@91061|Bacilli,1ZG8D@1386|Bacillus 91061|Bacilli - - yviE - - - - - - - - - - - - HPHIIJEP_02579 224308.BSU35380 1.23e-96 281.0 COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,4HKYD@91061|Bacilli,1ZI2D@1386|Bacillus 91061|Bacilli S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum fliW - - ko:K13626 - - - - ko00000,ko02035 - - - FliW HPHIIJEP_02580 224308.BSU35370 2.58e-41 136.0 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,4HNPJ@91061|Bacilli,1ZJ2S@1386|Bacillus 91061|Bacilli T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding csrA - - ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 - - - ko00000,ko00001,ko03019 - - - CsrA HPHIIJEP_02581 315750.BPUM_1150 2.33e-160 456.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,4H9UA@91061|Bacilli,1ZAQJ@1386|Bacillus 91061|Bacilli N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella hag GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N HPHIIJEP_02582 224308.BSU35350 9.02e-76 226.0 COG1334@1|root,COG1334@2|Bacteria,1VFRY@1239|Firmicutes,4HNSH@91061|Bacilli,1ZIZC@1386|Bacillus 91061|Bacilli N flagellar protein FlaG flaG - - ko:K06603 - - - - ko00000,ko02035 - - - FlaG HPHIIJEP_02583 1051501.AYTL01000004_gene3427 0.0 879.0 COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,4H9TN@91061|Bacilli,1ZCIG@1386|Bacillus 91061|Bacilli N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end fliD GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - ko:K02407 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flagellin_IN,FliD_C,FliD_N HPHIIJEP_02584 224308.BSU35330 1.48e-90 265.0 COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,4HIN5@91061|Bacilli,1ZH26@1386|Bacillus 91061|Bacilli N flagellar protein FliS fliS - - ko:K02422 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliS HPHIIJEP_02585 1294265.JCM21738_722 8.69e-09 56.6 2E69G@1|root,330XF@2|Bacteria,1VEKH@1239|Firmicutes,4HNWI@91061|Bacilli,1ZIW8@1386|Bacillus 91061|Bacilli S bacterial-type flagellum organization fliT - - ko:K02423 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - - HPHIIJEP_02586 224308.BSU35319 7.52e-87 255.0 2AQ94@1|root,31FEZ@2|Bacteria,1UA12@1239|Firmicutes,4IK9M@91061|Bacilli,1ZG21@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02587 224308.BSU35310 1.73e-132 375.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,1ZFW8@1386|Bacillus 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE HPHIIJEP_02588 224308.BSU35300 0.0 1640.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW HPHIIJEP_02589 224308.BSU35290 2e-232 641.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,1ZB5N@1386|Bacillus 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 HPHIIJEP_02590 224308.BSU35280 6.5e-185 516.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli,1ZC5M@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yvjA - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_02591 224308.BSU35270 4.42e-73 219.0 COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,1ZITU@1386|Bacillus 91061|Bacilli C COG2010 Cytochrome c, mono- and diheme variants cccB - - ko:K12263,ko:K13300 - - - - ko00000 - - - Cytochrome_CBB3 HPHIIJEP_02592 224308.BSU35260 1.5e-159 447.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,1ZCAE@1386|Bacillus 91061|Bacilli D cell division ATP-binding protein FtsE ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran HPHIIJEP_02593 224308.BSU35250 5.45e-199 553.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli,1ZC4Q@1386|Bacillus 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0032506,GO:0034097,GO:0042173,GO:0042221,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX HPHIIJEP_02594 224308.BSU35240 0.0 928.0 COG0793@1|root,COG3409@1|root,COG0793@2|Bacteria,COG3409@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpB GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 HPHIIJEP_02595 1051501.AYTL01000004_gene3438 1.38e-73 221.0 29RHV@1|root,30CKU@2|Bacteria,1UA28@1239|Firmicutes,4IKBF@91061|Bacilli,1ZGBI@1386|Bacillus 91061|Bacilli S Swarming motility protein swrA - - - - - - - - - - - SwrA HPHIIJEP_02596 224308.BSU35220 3.86e-281 769.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,1ZAQG@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain minJ - - - - - - - - - - - PDZ_2 HPHIIJEP_02597 224308.BSU35210 7.44e-296 810.0 COG0477@1|root,COG2814@2|Bacteria,1U4EP@1239|Firmicutes,4HAZC@91061|Bacilli,1ZC4J@1386|Bacillus 91061|Bacilli P -transporter yvkA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_02598 224308.BSU35200 1.43e-131 373.0 COG1309@1|root,COG1309@2|Bacteria,1V69B@1239|Firmicutes,4HIE0@91061|Bacilli,1ZEDX@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvkB GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_02599 224308.BSU35190 0.0 1632.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HDHF@91061|Bacilli,1ZQ5X@1386|Bacillus 91061|Bacilli GT Phosphotransferase yvkC - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N HPHIIJEP_02600 224308.BSU35180 2.54e-42 139.0 COG4897@1|root,COG4897@2|Bacteria,1VMTY@1239|Firmicutes,4HQMX@91061|Bacilli,1ZITV@1386|Bacillus 91061|Bacilli S protein conserved in bacteria csbA - - - - - - - - - - - DUF2198 HPHIIJEP_02601 224308.BSU35170 0.0 1274.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,1ZC50@1386|Bacillus 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB HPHIIJEP_02602 224308.BSU35160 0.0 1889.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1ZARC@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran HPHIIJEP_02603 1178537.BA1_11259 3.03e-147 420.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,4H9UA@91061|Bacilli,1ZAQJ@1386|Bacillus 91061|Bacilli N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella hag GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 - - - ko00000,ko00001,ko02035 - - - Flagellin_C,Flagellin_N HPHIIJEP_02604 224308.BSU35140 2.25e-45 146.0 29RWT@1|root,30D0Y@2|Bacteria,1UANW@1239|Firmicutes,4IM1I@91061|Bacilli,1ZIQG@1386|Bacillus 91061|Bacilli - - yvkN - - - - - - - - - - - - HPHIIJEP_02605 224308.BSU35130 8.09e-65 198.0 2DZIG@1|root,30CTN@2|Bacteria,1UACD@1239|Firmicutes,4IKQM@91061|Bacilli,1ZHD2@1386|Bacillus 91061|Bacilli - - yvlA - - - - - - - - - - - - HPHIIJEP_02606 224308.BSU35120 9.59e-220 611.0 COG3595@1|root,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,1ZC95@1386|Bacillus 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 HPHIIJEP_02607 224308.BSU35110 1.5e-36 123.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli,1ZJCV@1386|Bacillus 91061|Bacilli KT PspC domain yvlC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - DUF4097,PspC HPHIIJEP_02608 224308.BSU35100 3.8e-66 202.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,1ZI79@1386|Bacillus 91061|Bacilli S Membrane yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 HPHIIJEP_02609 224308.BSU35090 4.26e-272 746.0 COG0477@1|root,COG2814@2|Bacteria,1TR6I@1239|Firmicutes,4HCNW@91061|Bacilli,1ZFKW@1386|Bacillus 91061|Bacilli EGP Major Facilitator Superfamily yvmA - - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_02610 224308.BSU35080 6.2e-114 327.0 COG1846@1|root,COG1846@2|Bacteria,1VDUK@1239|Firmicutes,4HN0Q@91061|Bacilli,1ZQ3X@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein yvmB - - - - - - - - - - - MarR HPHIIJEP_02611 224308.BSU35070 8.35e-176 490.0 2E8AV@1|root,332PQ@2|Bacteria,1VVMM@1239|Firmicutes,4HWIF@91061|Bacilli,1ZMQK@1386|Bacillus 91061|Bacilli S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides yvmC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016740,GO:0016746,GO:0016755,GO:0042440,GO:0046148,GO:0140096 2.3.2.22 ko:K17485 - - - - ko00000,ko01000 - - - CDPS HPHIIJEP_02612 224308.BSU35060 2.45e-288 788.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 cypX GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006629,GO:0006706,GO:0006707,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016042,GO:0016053,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016713,GO:0017144,GO:0018130,GO:0019752,GO:0020037,GO:0032787,GO:0034641,GO:0036199,GO:0042364,GO:0042440,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046148,GO:0046164,GO:0046394,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.46,1.14.15.13 ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 HPHIIJEP_02613 224308.BSU35050 1.65e-93 274.0 COG1846@1|root,COG1846@2|Bacteria,1W0YZ@1239|Firmicutes,4HY82@91061|Bacilli,1ZQ3W@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein yvnA - - - - - - - - - - - MarR HPHIIJEP_02614 224308.BSU35040 0.0 2590.0 COG1409@1|root,COG1409@2|Bacteria,1TPQQ@1239|Firmicutes,4HC2W@91061|Bacilli,1ZCF0@1386|Bacillus 91061|Bacilli Q Calcineurin-like phosphoesterase yvnB - - - - - - - - - - - Gram_pos_anchor,LTD,Metallophos,fn3 HPHIIJEP_02615 224308.BSU35030 2.48e-170 476.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_02616 224308.BSU35020 1.67e-163 458.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,1ZD28@1386|Bacillus 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - iYO844.BSU02360,iYO844.BSU35020 Glucosamine_iso HPHIIJEP_02617 224308.BSU35010 3.99e-278 761.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,1ZCM7@1386|Bacillus 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 HPHIIJEP_02618 224308.BSU35000 3.62e-217 600.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,1ZD05@1386|Bacillus 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N HPHIIJEP_02619 224308.BSU34990 3.18e-195 541.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,1ZAR8@1386|Bacillus 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 - ko:K13292 - - - - ko00000,ko01000 - - - LGT HPHIIJEP_02620 224308.BSU34980 4.16e-208 577.0 COG0370@1|root,COG0370@2|Bacteria,1TQT3@1239|Firmicutes,4HAIZ@91061|Bacilli,1ZAYP@1386|Bacillus 91061|Bacilli P COG0370 Fe2 transport system protein B yvoD - - - - - - - - - - - Gate HPHIIJEP_02621 224308.BSU34970 3.05e-153 430.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4HE7X@91061|Bacilli,1ZB95@1386|Bacillus 91061|Bacilli S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool ppaX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 ko:K06019 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - HAD_2 HPHIIJEP_02622 224308.BSU34960 5.29e-121 345.0 COG0110@1|root,COG0110@2|Bacteria,1V1SM@1239|Firmicutes,4HFTP@91061|Bacilli,1ZBJ5@1386|Bacillus 91061|Bacilli S COG0110 Acetyltransferase (isoleucine patch superfamily) yvoF - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 HPHIIJEP_02623 224308.BSU34950 5.68e-156 437.0 COG5297@1|root,COG5297@2|Bacteria,1VSCG@1239|Firmicutes,4HVEI@91061|Bacilli 91061|Bacilli G Pectate lyase - - 4.2.2.10,4.2.2.2 ko:K19551 ko00040,map00040 - R02361 RC00049,RC00705 ko00000,ko00001,ko01000 - - - Pectate_lyase HPHIIJEP_02624 224308.BSU34940 6.12e-179 498.0 COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HK8M@91061|Bacilli,1ZDKM@1386|Bacillus 91061|Bacilli NU protein conserved in bacteria yvpB - - - - - - - - - - - Peptidase_C39_2 HPHIIJEP_02625 224308.BSU34930 1.15e-279 764.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,1ZB4H@1386|Bacillus 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His HPHIIJEP_02626 224308.BSU34920 1.06e-147 416.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,1ZCFW@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His HPHIIJEP_02627 224308.BSU34910 1.49e-291 798.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh HPHIIJEP_02628 224308.BSU34900 4.96e-139 392.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,1ZBVJ@1386|Bacillus 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD HPHIIJEP_02629 224308.BSU34890 1.1e-144 408.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HFXQ@91061|Bacilli,1ZBC4@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase HPHIIJEP_02630 224308.BSU34880 4.42e-165 462.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,1ZC7D@1386|Bacillus 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth HPHIIJEP_02631 224308.BSU34870 2.29e-175 489.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,1ZAUX@1386|Bacillus 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth HPHIIJEP_02632 224308.BSU34860 3.42e-142 402.0 COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,1ZDBB@1386|Bacillus 91061|Bacilli E belongs to the PRA-CH family hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH HPHIIJEP_02633 224308.BSU34850 2.27e-102 303.0 2E73G@1|root,331MZ@2|Bacteria,1VEY8@1239|Firmicutes,4HPNS@91061|Bacilli,1ZJRC@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02634 224308.BSU34840 6.12e-313 869.0 2CA56@1|root,2Z93A@2|Bacteria,1TSPR@1239|Firmicutes,4HAN6@91061|Bacilli,1ZEQ5@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - DUF2974 HPHIIJEP_02636 224308.BSU34820 0.0 1090.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,1ZCBG@1386|Bacillus 91061|Bacilli V ABC transporter lmrA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 3.6.3.44 ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran HPHIIJEP_02637 224308.BSU34810 0.0 956.0 COG0457@1|root,COG0457@2|Bacteria,1UBH2@1239|Firmicutes,4HB47@91061|Bacilli,1ZD40@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yvcD - - - - - - - - - - - HTH_psq,TPR_16,TPR_19,TPR_2,TPR_8 HPHIIJEP_02638 224308.BSU34800 2.68e-185 532.0 COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,4HDAX@91061|Bacilli,1ZCUD@1386|Bacillus 91061|Bacilli M protein conserved in bacteria spl - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 HPHIIJEP_02639 224308.BSU34790 1.18e-225 622.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,1ZBDJ@1386|Bacillus 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 HPHIIJEP_02640 224308.BSU34780 2.39e-117 335.0 COG1051@1|root,COG1051@2|Bacteria,1V66I@1239|Firmicutes,4HJEQ@91061|Bacilli,1ZQ2P@1386|Bacillus 91061|Bacilli F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes yvcI - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX HPHIIJEP_02641 224308.BSU34770 2.09e-213 589.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,1ZCWE@1386|Bacillus 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 HPHIIJEP_02642 224308.BSU34760 3.88e-226 624.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,1ZB2R@1386|Bacillus 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 HPHIIJEP_02643 224308.BSU34750 1.04e-219 607.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,1ZBKY@1386|Bacillus 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N HPHIIJEP_02644 224308.BSU34740 1.6e-49 157.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKKW@91061|Bacilli,1ZHV0@1386|Bacillus 91061|Bacilli G Phosphocarrier protein Chr crh - - ko:K11184 - - - - ko00000 - - - PTS-HPr HPHIIJEP_02645 224308.BSU34730 1.39e-183 510.0 COG2162@1|root,COG2162@2|Bacteria,1V4PB@1239|Firmicutes,4HHI4@91061|Bacilli,1ZCUM@1386|Bacillus 91061|Bacilli Q Belongs to the arylamine N-acetyltransferase family yvcN - 2.3.1.118 ko:K00675 - - - - ko00000,ko01000 - - - Acetyltransf_2 HPHIIJEP_02646 224308.BSU34729 5.4e-43 140.0 29SAN@1|root,30DF6@2|Bacteria,1UB89@1239|Firmicutes,4IMM0@91061|Bacilli,1ZKDV@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02647 224308.BSU34720 3.84e-171 477.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAQ7@91061|Bacilli,1ZE1M@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yvcP - - ko:K02483,ko:K11634 ko02020,map02020 M00470 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_02648 224308.BSU34710 3.78e-249 684.0 COG5002@1|root,COG5002@2|Bacteria,1UI6U@1239|Firmicutes,4ISFW@91061|Bacilli,1ZS5S@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain yvcQ - - - - - - - - - - - HATPase_c,HisKA HPHIIJEP_02649 224308.BSU34700 1.28e-180 503.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yxdL_2 - - ko:K02003,ko:K11635 ko02020,map02020 M00258,M00315 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134.6 - - ABC_tran HPHIIJEP_02650 224308.BSU34690 0.0 1193.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAG9@91061|Bacilli,1ZB66@1386|Bacillus 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX HPHIIJEP_02651 224308.BSU34680 2.7e-233 642.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,1ZB0I@1386|Bacillus 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family yvcT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 - R00465,R00717,R01388,R01392,R01739 RC00031,RC00042,RC00084 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C HPHIIJEP_02652 224308.BSU34670 8.79e-136 384.0 COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus 91061|Bacilli P Reversible hydration of carbon dioxide yvdA - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA HPHIIJEP_02653 224308.BSU34660 0.0 991.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli,1ZCKC@1386|Bacillus 91061|Bacilli P COG0659 Sulfate permease and related transporters (MFS superfamily) yvdB GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp HPHIIJEP_02654 224308.BSU34650 7.84e-71 213.0 COG1694@1|root,COG1694@2|Bacteria,1VA9N@1239|Firmicutes,4HMTD@91061|Bacilli,1ZRZC@1386|Bacillus 91061|Bacilli S MazG nucleotide pyrophosphohydrolase domain yvdC - - - - - - - - - - - MazG HPHIIJEP_02655 224308.BSU34640 5.37e-137 387.0 COG1611@1|root,COG1611@2|Bacteria,1V9MJ@1239|Firmicutes,4HIU1@91061|Bacilli,1ZQTF@1386|Bacillus 91061|Bacilli S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox HPHIIJEP_02656 224308.BSU34630 3.63e-220 608.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,1ZCWX@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvdE - - - - - - - - - - - LacI,Peripla_BP_3 HPHIIJEP_02657 224308.BSU34620 0.0 1221.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,1ZAZP@1386|Bacillus 91061|Bacilli G Alpha amylase, N-terminal ig-like domain nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C HPHIIJEP_02658 224308.BSU34610 4.19e-302 823.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains mdxE - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - iYO844.BSU34610 SBP_bac_8 HPHIIJEP_02659 224308.BSU34600 3.52e-310 845.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 HPHIIJEP_02660 224308.BSU34590 6.84e-190 528.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,1ZB5C@1386|Bacillus 91061|Bacilli P transport malD GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 HPHIIJEP_02661 224308.BSU34580 3.4e-198 550.0 COG5521@1|root,COG5521@2|Bacteria,1V7S4@1239|Firmicutes,4HJ3V@91061|Bacilli,1ZF9A@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) malA - - - - - - - - - - - DUF1189 HPHIIJEP_02662 224308.BSU34570 0.0 1517.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,1ZBSM@1386|Bacillus 91061|Bacilli G Glycoside hydrolase, family 65 yvdK GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m HPHIIJEP_02663 224308.BSU34560 0.0 1168.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases malL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C HPHIIJEP_02664 224308.BSU34550 1.31e-147 417.0 COG0637@1|root,COG0637@2|Bacteria,1V389@1239|Firmicutes,4HGHQ@91061|Bacilli,1ZQ74@1386|Bacillus 91061|Bacilli S Haloacid dehalogenase-like hydrolase pgmB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008801,GO:0016853,GO:0016866,GO:0016868,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0071704 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 HPHIIJEP_02665 224308.BSU34540 8.17e-135 382.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,1ZARS@1386|Bacillus 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease HPHIIJEP_02667 224308.BSU34510 1.12e-121 347.0 2DBXC@1|root,2ZBP3@2|Bacteria,1V1I2@1239|Firmicutes,4HB52@91061|Bacilli,1ZFJV@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3231) yvdQ - - - - - - - - - - - DUF3231 HPHIIJEP_02668 224308.BSU34500 1.03e-66 202.0 COG2076@1|root,COG2076@2|Bacteria,1VE2R@1239|Firmicutes,4HKJB@91061|Bacilli,1ZIIC@1386|Bacillus 91061|Bacilli P Small Multidrug Resistance protein yvdR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res HPHIIJEP_02669 224308.BSU34490 1.74e-65 200.0 COG2076@1|root,COG2076@2|Bacteria,1VA4Z@1239|Firmicutes,4HKVF@91061|Bacilli,1ZIHS@1386|Bacillus 91061|Bacilli P Small Multidrug Resistance protein yvdS GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K18924 - M00712 - - ko00000,ko00002,ko02000 2.A.7.1.5 - - Multi_Drug_Res HPHIIJEP_02670 224308.BSU34480 7.9e-136 384.0 COG1309@1|root,COG1309@2|Bacteria,1V4J3@1239|Firmicutes,4HHPI@91061|Bacilli,1ZG5D@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvdT_1 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_C_4,TetR_N HPHIIJEP_02671 224308.BSU34470 0.0 1025.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HC13@91061|Bacilli,1ZCG6@1386|Bacillus 91061|Bacilli E amino acid ybeC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 HPHIIJEP_02672 224308.BSU34460 0.0 1086.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZE06@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 32 family sacC3 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.65 ko:K01212 ko00500,map00500 - R05624,R11311 RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N HPHIIJEP_02673 224308.BSU34450 0.0 952.0 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli,1ZBRC@1386|Bacillus 91061|Bacilli M levansucrase activity sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 HPHIIJEP_02674 720555.BATR1942_15130 7.19e-86 257.0 2E6XN@1|root,331GZ@2|Bacteria,1VGPQ@1239|Firmicutes,4HQH8@91061|Bacilli,1ZI8H@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - C1q HPHIIJEP_02675 224308.BSU34440 0.0 897.0 COG1680@1|root,COG1680@2|Bacteria,1UZUZ@1239|Firmicutes,4IPQ5@91061|Bacilli,1ZG0V@1386|Bacillus 91061|Bacilli V Beta-lactamase pbpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Beta-lactamase,DUF3471 HPHIIJEP_02676 224308.BSU34430 1.51e-163 457.0 COG1794@1|root,COG1794@2|Bacteria,1V1BP@1239|Firmicutes,4HFX8@91061|Bacilli,1ZQCX@1386|Bacillus 91061|Bacilli M Belongs to the aspartate glutamate racemases family racX - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race HPHIIJEP_02677 1051501.AYTL01000004_gene3521 1.75e-93 274.0 2DMP1@1|root,32SS8@2|Bacteria,1VFZZ@1239|Firmicutes,4HX01@91061|Bacilli,1ZJV7@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3237) - - - - - - - - - - - - DUF3237 HPHIIJEP_02678 224308.BSU34400 5.4e-120 342.0 COG3479@1|root,COG3479@2|Bacteria,1UY0X@1239|Firmicutes,4HAN3@91061|Bacilli,1ZF2A@1386|Bacillus 91061|Bacilli Q Phenolic acid decarboxylase padC - - ko:K13727 - - - - ko00000,ko01000 - - - PA_decarbox HPHIIJEP_02680 224308.BSU34390 0.0 981.0 COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,4HCKV@91061|Bacilli,1ZEEU@1386|Bacillus 91061|Bacilli I Belongs to the type-B carboxylesterase lipase family pnbA - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase HPHIIJEP_02681 224308.BSU34380 3.57e-98 286.0 COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZFHM@1386|Bacillus 91061|Bacilli K transcriptional - - - ko:K19417 - - - - ko00000,ko03000 - - - HTH_3,SinI HPHIIJEP_02682 224308.BSU34370 1.61e-157 442.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,1ZBJ4@1386|Bacillus 91061|Bacilli M biosynthesis protein epsA - - ko:K19420 - - - - ko00000 - - - GNVR,Wzz HPHIIJEP_02683 224308.BSU34360 7.94e-150 422.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,1ZB83@1386|Bacillus 91061|Bacilli D COG0489 ATPases involved in chromosome partitioning ywqD - 2.7.10.2 ko:K00903 - - - - ko00000,ko01000,ko01001 - - - AAA_31,ParA HPHIIJEP_02684 224308.BSU34350 0.0 1154.0 COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1ZB9K@1386|Bacillus 91061|Bacilli GM Polysaccharide biosynthesis protein capD GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - ko:K19421 - - - - ko00000 - - - CoA_binding_3,Polysacc_synt_2 HPHIIJEP_02685 224308.BSU34340 3.17e-281 768.0 COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,4HCN6@91061|Bacilli,1ZD2Y@1386|Bacillus 91061|Bacilli M Glycosyl transferase 4-like epsD GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K19422 - - - - ko00000,ko01000 - GT4 - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 HPHIIJEP_02686 224308.BSU34330 1.25e-201 558.0 COG1215@1|root,COG1215@2|Bacteria,1UZRX@1239|Firmicutes,4HGN8@91061|Bacilli,1ZEKC@1386|Bacillus 91061|Bacilli M COG0463 Glycosyltransferases involved in cell wall biogenesis epsE - - ko:K19423 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 HPHIIJEP_02687 224308.BSU34320 5.06e-278 760.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli,1ZEMI@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 epsF GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 HPHIIJEP_02688 224308.BSU34310 5.1e-264 723.0 2DP3I@1|root,330DE@2|Bacteria,1UPRV@1239|Firmicutes,4HS3P@91061|Bacilli,1ZSJX@1386|Bacillus 91061|Bacilli S EpsG family epsG - - ko:K19419 - - - - ko00000,ko02000 9.B.183.1.9 - - EpsG HPHIIJEP_02689 224308.BSU34300 2.02e-247 679.0 COG1216@1|root,COG1216@2|Bacteria,1VJX3@1239|Firmicutes,4HWYT@91061|Bacilli,1ZDMT@1386|Bacillus 91061|Bacilli S Glycosyltransferase like family 2 epsH GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K19425 - - - - ko00000,ko01000,ko01003 - GT2 - Glycos_transf_2 HPHIIJEP_02690 224308.BSU34290 3.16e-258 707.0 COG5039@1|root,COG5039@2|Bacteria,1V5MK@1239|Firmicutes,4HJ1D@91061|Bacilli,1ZEEK@1386|Bacillus 91061|Bacilli GM pyruvyl transferase epsI - - ko:K19426 - - - - ko00000,ko01000 - - - PS_pyruv_trans HPHIIJEP_02691 224308.BSU34280 4.97e-248 681.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,1ZFI5@1386|Bacillus 91061|Bacilli S COG0463 Glycosyltransferases involved in cell wall biogenesis epsJ GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K19427 - - - - ko00000,ko01000 - GT2 - Glycos_transf_2 HPHIIJEP_02692 224308.BSU34265 0.0 919.0 COG2244@1|root,COG2244@2|Bacteria,1TQBD@1239|Firmicutes,4HTU0@91061|Bacilli,1ZAXV@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid epsK GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19418 - - - - ko00000,ko02000 - - - Polysacc_synt,Polysacc_synt_C HPHIIJEP_02693 224308.BSU34250 9.14e-139 392.0 COG2148@1|root,COG2148@2|Bacteria,1TP49@1239|Firmicutes,4HFZV@91061|Bacilli,1ZC89@1386|Bacillus 91061|Bacilli M COG2148 Sugar transferases involved in lipopolysaccharide synthesis epsL GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0016740,GO:0016772,GO:0016780,GO:0043170,GO:0044238,GO:0071704 - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf HPHIIJEP_02694 224308.BSU34240 8.22e-77 237.0 COG0110@1|root,COG0110@2|Bacteria,1V8CV@1239|Firmicutes,4HJ0P@91061|Bacilli,1ZGBH@1386|Bacillus 91061|Bacilli GM COG0110 Acetyltransferase (isoleucine patch superfamily) epsM GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 - ko:K19429 - - - - ko00000,ko01000 - - - Hexapep HPHIIJEP_02695 224308.BSU34230 8.34e-276 754.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HBZ8@91061|Bacilli,1ZCTS@1386|Bacillus 91061|Bacilli E Belongs to the DegT DnrJ EryC1 family epsN - - ko:K19430 - - - - ko00000,ko01000 - - - DegT_DnrJ_EryC1 HPHIIJEP_02696 224308.BSU34220 2.83e-236 649.0 COG5039@1|root,COG5039@2|Bacteria,1V5MK@1239|Firmicutes,4HJ1D@91061|Bacilli 91061|Bacilli GM Exopolysaccharide biosynthesis protein epsO - - ko:K19431 - - - - ko00000,ko01000 - - - PS_pyruv_trans HPHIIJEP_02697 224308.BSU34210 5.69e-44 142.0 2EM15@1|root,33EQP@2|Bacteria,1VN1G@1239|Firmicutes,4HSEP@91061|Bacilli,1ZI1T@1386|Bacillus 91061|Bacilli S YvfG protein yvfG - - - - - - - - - - - YvfG HPHIIJEP_02698 224308.BSU34200 4.96e-306 835.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,1ZBKU@1386|Bacillus 91061|Bacilli K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD HPHIIJEP_02699 224308.BSU34190 0.0 1067.0 COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli,1ZC0U@1386|Bacillus 91061|Bacilli C L-lactate permease lctP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03303 - - - - ko00000,ko02000 2.A.14 - - Lactate_perm HPHIIJEP_02700 1051501.AYTL01000004_gene3544 6.85e-146 414.0 COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,4HDHI@91061|Bacilli,1ZD1T@1386|Bacillus 91061|Bacilli K COG2186 Transcriptional regulators yvfI - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR HPHIIJEP_02701 224308.BSU34170 9.89e-237 651.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,1ZD8J@1386|Bacillus 91061|Bacilli K Transcriptional regulator lacR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_02702 224308.BSU34160 4.62e-292 798.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,1ZBWG@1386|Bacillus 91061|Bacilli G COG2182 Maltose-binding periplasmic proteins domains cycB - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - iYO844.BSU34610 SBP_bac_8 HPHIIJEP_02703 224308.BSU34150 1.3e-301 822.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,1ZBHD@1386|Bacillus 91061|Bacilli P COG1175 ABC-type sugar transport systems, permease components malC GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351 - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - iYO844.BSU34150 BPD_transp_1 HPHIIJEP_02704 224308.BSU34140 3.82e-194 539.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,1ZB5C@1386|Bacillus 91061|Bacilli P transport malG GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0033037,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043211,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 HPHIIJEP_02705 224308.BSU34130 0.0 1420.0 COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,1ZCHT@1386|Bacillus 91061|Bacilli G beta-galactosidase lacA - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M HPHIIJEP_02706 224308.BSU34120 0.0 872.0 COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli,1ZBZ2@1386|Bacillus 91061|Bacilli G arabinogalactan ganB - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Big_4,Glyco_hydro_53,Gram_pos_anchor,SLH HPHIIJEP_02707 224308.BSU34110 1.52e-265 730.0 COG2208@1|root,COG2208@2|Bacteria,1TS3B@1239|Firmicutes,4HCRR@91061|Bacilli,1ZBBE@1386|Bacillus 91061|Bacilli T response regulator - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - PAS,PAS_9,SpoIIE HPHIIJEP_02708 224308.BSU34100 1.46e-200 554.0 COG0596@1|root,COG0596@2|Bacteria,1TREC@1239|Firmicutes,4HAPB@91061|Bacilli,1ZDQB@1386|Bacillus 91061|Bacilli S Alpha/beta hydrolase family rsbQ - - ko:K19707 - - - - ko00000,ko03021 - - - Abhydrolase_1,Abhydrolase_6 HPHIIJEP_02710 224308.BSU34090 7.76e-205 568.0 COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,1ZCK0@1386|Bacillus 91061|Bacilli V COG1131 ABC-type multidrug transport system, ATPase component yvfR - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_02711 224308.BSU34080 2.04e-170 476.0 COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,1ZD2I@1386|Bacillus 91061|Bacilli V COG0842 ABC-type multidrug transport system, permease component XK27_09830 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 HPHIIJEP_02712 224308.BSU34070 4.24e-249 686.0 COG4585@1|root,COG4585@2|Bacteria,1UXXW@1239|Firmicutes,4HCS6@91061|Bacilli,1ZPXJ@1386|Bacillus 91061|Bacilli T Histidine kinase yvfT - 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 HPHIIJEP_02713 224308.BSU34060 4.36e-136 385.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus 91061|Bacilli T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_02714 224308.BSU34050 3.04e-173 483.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,1ZCUT@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source lutA - - ko:K18928 - - - - ko00000 - - - CCG HPHIIJEP_02715 224308.BSU34040 0.0 941.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,1ZCJB@1386|Bacillus 91061|Bacilli C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom HPHIIJEP_02716 224308.BSU34030 2.92e-172 480.0 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,1ZCX9@1386|Bacillus 91061|Bacilli S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom HPHIIJEP_02717 224308.BSU34020 4.44e-251 688.0 COG3858@1|root,COG3858@2|Bacteria,1UY7M@1239|Firmicutes,4HDBG@91061|Bacilli,1ZREZ@1386|Bacillus 91061|Bacilli S Glycosyl hydrolase - - - - - - - - - - - - Glyco_hydro_18 HPHIIJEP_02718 224308.BSU34010 2.03e-306 837.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZS14@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases yvbW - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease HPHIIJEP_02719 224308.BSU34000 5.59e-198 551.0 COG0697@1|root,COG0697@2|Bacteria,1TRJZ@1239|Firmicutes,4HDJI@91061|Bacilli,1ZCMU@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yvbV - - - - - - - - - - - EamA HPHIIJEP_02720 224308.BSU33990 3.45e-206 570.0 COG0583@1|root,COG0583@2|Bacteria,1V275@1239|Firmicutes,4HK7I@91061|Bacilli,1ZDKT@1386|Bacillus 91061|Bacilli K Transcriptional regulator yvbU GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363,GO:1990837 - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_02721 224308.BSU33980 1.04e-245 674.0 COG2141@1|root,COG2141@2|Bacteria,1TQWJ@1239|Firmicutes,4HBMR@91061|Bacilli,1ZAPR@1386|Bacillus 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases yvbT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Bac_luciferase HPHIIJEP_02722 224308.BSU33970 1.51e-258 709.0 COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,4HARD@91061|Bacilli,1ZBZA@1386|Bacillus 91061|Bacilli K transcriptional araR - - ko:K02103 - - - - ko00000,ko03000 - - - GntR,Peripla_BP_3 HPHIIJEP_02723 224308.BSU33960 0.0 886.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,1ZAUM@1386|Bacillus 91061|Bacilli U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family araE GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1,2.A.1.1.2,2.A.1.1.26 - - Sugar_tr HPHIIJEP_02724 224308.BSU33950 5.69e-236 650.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,1ZBYA@1386|Bacillus 91061|Bacilli K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind HPHIIJEP_02725 224308.BSU33940 5.72e-238 654.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N HPHIIJEP_02726 224308.BSU33930 1.97e-277 759.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1ZCXW@1386|Bacillus 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK HPHIIJEP_02727 224308.BSU33920 2.12e-176 492.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,1ZB6N@1386|Bacillus 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM HPHIIJEP_02728 224308.BSU33910 0.0 1023.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,4HBTQ@91061|Bacilli,1ZAPE@1386|Bacillus 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N HPHIIJEP_02729 224308.BSU33900 1.38e-309 843.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N HPHIIJEP_02730 720555.BATR1942_14925 4.27e-209 589.0 COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes,4HBE5@91061|Bacilli,1ZC0A@1386|Bacillus 91061|Bacilli S PA domain ywaD - 3.4.11.10,3.4.11.6 ko:K19701 - - - - ko00000,ko01000,ko01002 - - - PA,Peptidase_M28 HPHIIJEP_02731 720555.BATR1942_14920 6.43e-274 754.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1ZDXJ@1386|Bacillus 91061|Bacilli M UDP binding domain - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N HPHIIJEP_02732 326423.RBAM_031230 2.64e-234 649.0 COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,1ZQW8@1386|Bacillus 91061|Bacilli E Belongs to the DegT DnrJ EryC1 family - - 2.6.1.102 ko:K13010 ko00520,map00520 - R10460 RC00006,RC00781 ko00000,ko00001,ko01000,ko01005,ko01007 - - - DegT_DnrJ_EryC1 HPHIIJEP_02733 326423.RBAM_031220 7.08e-187 523.0 COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HAY0@91061|Bacilli,1ZF5A@1386|Bacillus 91061|Bacilli M GDP-mannose 4,6 dehydratase arnA - 4.2.1.46,5.1.3.2 ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 M00361,M00362,M00632,M00793 R00291,R02984,R06513 RC00289,RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase HPHIIJEP_02734 326423.RBAM_031210 1.21e-198 561.0 COG0399@1|root,COG0399@2|Bacteria 2|Bacteria E UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - - - - - - - - - - DegT_DnrJ_EryC1,Y2_Tnp HPHIIJEP_02735 326423.RBAM_031200 2.55e-144 411.0 COG5653@1|root,COG5653@2|Bacteria 2|Bacteria M Protein involved in cellulose biosynthesis - - - - - - - - - - - - Acetyltransf_6 HPHIIJEP_02736 720555.BATR1942_14895 3.37e-156 440.0 COG0224@1|root,COG0224@2|Bacteria,1UJD7@1239|Firmicutes 1239|Firmicutes C WbqC-like protein family - - - - - - - - - - - - WbqC HPHIIJEP_02737 720555.BATR1942_14890 5.37e-147 415.0 COG2120@1|root,COG2120@2|Bacteria,1UZDV@1239|Firmicutes,4HE79@91061|Bacilli,1ZF1S@1386|Bacillus 91061|Bacilli S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L HPHIIJEP_02738 326423.RBAM_031170 1.25e-192 537.0 2F5JR@1|root,33Y4Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - HPHIIJEP_02739 326423.RBAM_031160 2.55e-217 608.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 HPHIIJEP_02740 224308.BSU33890 9.77e-106 305.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,1ZGDE@1386|Bacillus 91061|Bacilli K acetyltransferase yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 HPHIIJEP_02741 224308.BSU33880 0.0 1164.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,1ZCS9@1386|Bacillus 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 HPHIIJEP_02742 224308.BSU33870 1.13e-156 440.0 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HIHS@91061|Bacilli 91061|Bacilli M Membrane yvbI - - - - - - - - - - - - HPHIIJEP_02743 224308.BSU33860 2.96e-145 409.0 28IW6@1|root,2Z8UG@2|Bacteria,1TSGG@1239|Firmicutes,4HCTI@91061|Bacilli,1ZBNE@1386|Bacillus 91061|Bacilli S YvbH-like oligomerisation region yvbH - - - - - - - - - - - YvbH_ext,bPH_1 HPHIIJEP_02744 224308.BSU33850 9.68e-136 385.0 COG2095@1|root,COG2095@2|Bacteria,1V81W@1239|Firmicutes,4HIUV@91061|Bacilli,1ZDG0@1386|Bacillus 91061|Bacilli U UPF0056 membrane protein yvbG - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC HPHIIJEP_02745 224308.BSU33840 8.29e-129 366.0 COG1510@1|root,COG1510@2|Bacteria,1V7DN@1239|Firmicutes,4HJUD@91061|Bacilli,1ZFI3@1386|Bacillus 91061|Bacilli K Belongs to the GbsR family yvbF - - ko:K22301 - - - - ko00000,ko03000 - - - MarR_2 HPHIIJEP_02746 224308.BSU33830 5.58e-270 739.0 COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,1ZBIG@1386|Bacillus 91061|Bacilli E COG1125 ABC-type proline glycine betaine transport systems, ATPase components opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS HPHIIJEP_02747 224308.BSU33820 5.63e-145 409.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,1ZQFM@1386|Bacillus 91061|Bacilli P COG1174 ABC-type proline glycine betaine transport systems, permease component opuCB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071705,GO:0071944 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33720 BPD_transp_1 HPHIIJEP_02748 224308.BSU33810 7.4e-223 613.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,1ZQFN@1386|Bacillus 91061|Bacilli M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC HPHIIJEP_02749 224308.BSU33800 5.59e-136 387.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,1ZCXV@1386|Bacillus 91061|Bacilli P COG1174 ABC-type proline glycine betaine transport systems, permease component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 HPHIIJEP_02750 224308.BSU33740 6.63e-122 348.0 COG1510@1|root,COG1510@2|Bacteria,1V7DN@1239|Firmicutes,4HJUD@91061|Bacilli,1ZFI3@1386|Bacillus 91061|Bacilli K Belongs to the GbsR family yvbF - - ko:K22301 - - - - ko00000,ko03000 - - - MarR_2 HPHIIJEP_02751 224308.BSU33730 1.42e-268 736.0 COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,1ZBIG@1386|Bacillus 91061|Bacilli E COG1125 ABC-type proline glycine betaine transport systems, ATPase components opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS HPHIIJEP_02752 224308.BSU33720 1.55e-142 403.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,1ZQFM@1386|Bacillus 91061|Bacilli P COG1174 ABC-type proline glycine betaine transport systems, permease component opuCB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071705,GO:0071944 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33720 BPD_transp_1 HPHIIJEP_02753 224308.BSU33710 6.52e-218 601.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,1ZQFN@1386|Bacillus 91061|Bacilli M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC HPHIIJEP_02754 224308.BSU33700 2.26e-144 409.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,1ZCXV@1386|Bacillus 91061|Bacilli P COG1174 ABC-type proline glycine betaine transport systems, permease component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 HPHIIJEP_02755 224308.BSU33690 0.0 880.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein yvaQ - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal HPHIIJEP_02756 224308.BSU33680 3.85e-72 216.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus 91061|Bacilli K transcriptional yvaP GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR HPHIIJEP_02757 224308.BSU33670 9.82e-92 268.0 COG1396@1|root,COG1396@2|Bacteria,1VKJA@1239|Firmicutes,4HITA@91061|Bacilli,1ZQBP@1386|Bacillus 91061|Bacilli K Cro/C1-type HTH DNA-binding domain yvaO - - ko:K22299 - - - - ko00000,ko03000 - - - HTH_19,HTH_3,HTH_31 HPHIIJEP_02758 224308.BSU33660 2.36e-91 267.0 COG1396@1|root,COG1396@2|Bacteria,1VKJA@1239|Firmicutes,4HITA@91061|Bacilli,1ZGS0@1386|Bacillus 91061|Bacilli K transcriptional yvaO - - ko:K22299 - - - - ko00000,ko03000 - - - HTH_19,HTH_3,HTH_31 HPHIIJEP_02759 224308.BSU33650 4.9e-48 153.0 COG1476@1|root,COG1476@2|Bacteria,1UAIJ@1239|Firmicutes,4IKX1@91061|Bacilli,1ZI5J@1386|Bacillus 91061|Bacilli K transcriptional yvzC - - - - - - - - - - - HTH_3 HPHIIJEP_02760 224308.BSU33640 2.33e-195 540.0 COG0596@1|root,COG0596@2|Bacteria,1V619@1239|Firmicutes,4HCRW@91061|Bacilli,1ZDX1@1386|Bacillus 91061|Bacilli S Serine aminopeptidase, S33 yvaM - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 HPHIIJEP_02761 1051501.AYTL01000004_gene3595 1.87e-35 121.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,1ZHZV@1386|Bacillus 91061|Bacilli U Preprotein translocase subunit SecG secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG HPHIIJEP_02762 224308.BSU33620 3.43e-183 508.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,1ZAVD@1386|Bacillus 91061|Bacilli S Carboxylesterase est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 HPHIIJEP_02763 224308.BSU33610 0.0 1488.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,1ZBDP@1386|Bacillus 91061|Bacilli K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 HPHIIJEP_02764 224308.BSU33600 6.89e-107 308.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus 91061|Bacilli O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB HPHIIJEP_02766 224308.BSU33590 3.96e-182 507.0 COG1028@1|root,COG1028@2|Bacteria,1TPZN@1239|Firmicutes,4HBJ8@91061|Bacilli,1ZF72@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yvaG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short HPHIIJEP_02767 224308.BSU33580 7.87e-125 356.0 COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,4HIHV@91061|Bacilli,1ZR38@1386|Bacillus 91061|Bacilli K Bacterial regulatory proteins, tetR family - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_02768 224308.BSU33570 3.52e-71 215.0 COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HNJX@91061|Bacilli,1ZHWT@1386|Bacillus 91061|Bacilli P Small Multidrug Resistance protein yvaE - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res HPHIIJEP_02769 224308.BSU33560 5.79e-97 281.0 2A3NR@1|root,30S65@2|Bacteria,1V5EJ@1239|Firmicutes,4HHP8@91061|Bacilli,1ZQKJ@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5360) yvaD - - - - - - - - - - - DUF5360 HPHIIJEP_02770 224308.BSU33550 0.0 1197.0 COG1289@1|root,COG1289@2|Bacteria,1UU7Y@1239|Firmicutes,4HE9J@91061|Bacilli,1ZEB5@1386|Bacillus 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - FUSC-like,FUSC_2 HPHIIJEP_02771 224308.BSU33540 3.59e-154 432.0 COG1182@1|root,COG1182@2|Bacteria,1UZBY@1239|Firmicutes,4HB1Z@91061|Bacilli,1ZD4D@1386|Bacillus 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 HPHIIJEP_02772 224308.BSU33530 6.66e-246 676.0 COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,4HBHI@91061|Bacilli,1ZDU7@1386|Bacillus 91061|Bacilli S Oxidoreductase yvaA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_02773 224308.BSU33520 6.89e-65 197.0 COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HKJV@91061|Bacilli,1ZQH8@1386|Bacillus 91061|Bacilli S transcriptional csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal HPHIIJEP_02774 224308.BSU33510 3.66e-41 135.0 COG2608@1|root,COG2608@2|Bacteria,1VERB@1239|Firmicutes,4HNP0@91061|Bacilli,1ZITG@1386|Bacillus 91061|Bacilli P Copper resistance protein CopZ copZ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07213 ko04978,map04978 - - - ko00000,ko00001 - - - HMA HPHIIJEP_02775 224308.BSU33500 0.0 1499.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,1ZAVE@1386|Bacillus 91061|Bacilli P P-type ATPase copA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase HPHIIJEP_02776 224308.BSU33490 0.0 1288.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,1ZAPS@1386|Bacillus 91061|Bacilli P COG2217 Cation transport ATPase cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase HPHIIJEP_02777 224308.BSU33480 3.45e-137 390.0 COG1651@1|root,COG1651@2|Bacteria,1V6IC@1239|Firmicutes,4HKJU@91061|Bacilli,1ZE03@1386|Bacillus 91061|Bacilli O Thioredoxin bdbD - - - - - - - - - - - Thioredoxin_4 HPHIIJEP_02778 224308.BSU33470 1.99e-95 278.0 COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,1ZH0E@1386|Bacillus 91061|Bacilli O Required for disulfide bond formation in some proteins bdbC - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB HPHIIJEP_02779 224308.BSU33460 2.34e-139 394.0 COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,4HDC7@91061|Bacilli,1ZBS1@1386|Bacillus 91061|Bacilli S membrane yvgT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - UPF0126 HPHIIJEP_02781 224308.BSU33450 0.0 1515.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,1ZAWP@1386|Bacillus 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 HPHIIJEP_02782 224308.BSU33440 0.0 1188.0 COG0369@1|root,COG0369@2|Bacteria,1TP5J@1239|Firmicutes,4HCQI@91061|Bacilli,1ZANY@1386|Bacillus 91061|Bacilli P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU33440 FAD_binding_1,Flavodoxin_1,NAD_binding_1 HPHIIJEP_02783 224308.BSU33430 0.0 1157.0 COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,4HBEX@91061|Bacilli,1ZBHT@1386|Bacillus 91061|Bacilli P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2,1.8.7.1 ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858,R00859,R03600 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr HPHIIJEP_02784 224308.BSU33420 0.0 1199.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,1ZB41@1386|Bacillus 91061|Bacilli P COG0025 NhaP-type Na H and K H antiporters yvgP GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger HPHIIJEP_02785 224308.BSU33410 7.97e-113 323.0 2EKDS@1|root,33E41@2|Bacteria,1VVGE@1239|Firmicutes,4HW4S@91061|Bacilli,1ZFNW@1386|Bacillus 91061|Bacilli - - yvgO - - - - - - - - - - - - HPHIIJEP_02786 224308.BSU33400 6.19e-201 556.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus 91061|Bacilli S reductase yvgN - - - - - - - - - - - Aldo_ket_red HPHIIJEP_02787 224308.BSU33390 1.74e-153 432.0 COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,4HEA2@91061|Bacilli,1ZATK@1386|Bacillus 91061|Bacilli P COG4149 ABC-type molybdate transport system, permease component modB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 HPHIIJEP_02788 224308.BSU33380 8.23e-175 488.0 COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,4HG0Q@91061|Bacilli,1ZBKR@1386|Bacillus 91061|Bacilli P COG0725 ABC-type molybdate transport system, periplasmic component modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 HPHIIJEP_02789 224308.BSU33370 2.97e-213 590.0 COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,4HAJV@91061|Bacilli,1ZC11@1386|Bacillus 91061|Bacilli P COG1910 Periplasmic molybdate-binding protein domain yvgK - - ko:K07219 - - - - ko00000 - - - HTH_17,HTH_3,PBP_like HPHIIJEP_02790 224308.BSU33360 0.0 1209.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZF0R@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yvgJ - - ko:K01138 - - - - ko00000,ko01000 - - - Sulfatase HPHIIJEP_02791 224308.BSU33350 2.38e-109 315.0 COG1988@1|root,COG1988@2|Bacteria,1V3QT@1239|Firmicutes,4HGYG@91061|Bacilli,1ZFRV@1386|Bacillus 91061|Bacilli S LexA-binding, inner membrane-associated putative hydrolase yvsG - - ko:K07038 - - - - ko00000 - - - YdjM HPHIIJEP_02792 1051501.AYTL01000004_gene3628 9.37e-23 87.4 29S4R@1|root,30D99@2|Bacteria,1UB0W@1239|Firmicutes,4IMDS@91061|Bacilli,1ZJWM@1386|Bacillus 91061|Bacilli S Small spore protein J (Spore_SspJ) - - - ko:K06427 - - - - ko00000 - - - Spore_SspJ HPHIIJEP_02793 224308.BSU33330 0.0 875.0 COG0531@1|root,COG0531@2|Bacteria,1TSSB@1239|Firmicutes,4HA92@91061|Bacilli,1ZCJ6@1386|Bacillus 91061|Bacilli E Arginine ornithine antiporter yvsH - - ko:K03294,ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - iYO844.BSU33330 AA_permease_2 HPHIIJEP_02794 224308.BSU33320 3.13e-225 620.0 COG0614@1|root,COG0614@2|Bacteria,1V2E9@1239|Firmicutes,4IPYF@91061|Bacilli,1ZREY@1386|Bacillus 91061|Bacilli P ABC transporter fhuD GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 HPHIIJEP_02795 224308.BSU33310 2e-235 650.0 COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,4HA75@91061|Bacilli,1ZC7Z@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuB GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0008150,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071944 - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD HPHIIJEP_02796 224308.BSU33300 4.78e-226 624.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAM8@91061|Bacilli,1ZAU0@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fhuG - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33300 FecCD HPHIIJEP_02797 224308.BSU33290 2.92e-191 531.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter fhuC - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran HPHIIJEP_02799 224308.BSU33280 3.61e-231 642.0 COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,4HMJ5@91061|Bacilli,1ZQX7@1386|Bacillus 91061|Bacilli M Efflux transporter rnd family, mfp subunit - - - ko:K02005 - - - - ko00000 - - - HlyD_3,HlyD_D23 HPHIIJEP_02800 224308.BSU33270 3.82e-158 444.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1ZC14@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein yvrO - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_02801 224308.BSU33260 7.7e-273 749.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HATE@91061|Bacilli,1ZDCS@1386|Bacillus 91061|Bacilli V COG0577 ABC-type antimicrobial peptide transport system, permease component yvrN GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HPHIIJEP_02802 224308.BSU33250 9.89e-86 253.0 29RHZ@1|root,30CKY@2|Bacteria,1UA2J@1239|Firmicutes,4IKBU@91061|Bacilli,1ZGDA@1386|Bacillus 91061|Bacilli S Regulatory protein YrvL yvrL - - - - - - - - - - - YrvL HPHIIJEP_02803 224308.BSU33240 9.23e-292 795.0 COG2140@1|root,COG2140@2|Bacteria,1TPC2@1239|Firmicutes,4HA6V@91061|Bacilli,1ZF6R@1386|Bacillus 91061|Bacilli G Oxalate decarboxylase oxdC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 - R00522 RC00321 ko00000,ko00001,ko01000 - - iYO844.BSU18670 Cupin_1 HPHIIJEP_02804 224308.BSU33239 3.46e-26 98.2 29SDU@1|root,30DIK@2|Bacteria,1UBBR@1239|Firmicutes,4IMQN@91061|Bacilli,1ZKMF@1386|Bacillus 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ HPHIIJEP_02805 1051501.AYTL01000004_gene3640 7.02e-128 364.0 COG1191@1|root,COG1191@2|Bacteria,1VF0Z@1239|Firmicutes,4HNZQ@91061|Bacilli,1ZESN@1386|Bacillus 91061|Bacilli K RNA polymerase yvrI - - ko:K03093 - - - - ko00000,ko03021 - - - Sigma70_r4 HPHIIJEP_02806 326423.RBAM_030360 8.75e-33 115.0 2DRUJ@1|root,33D4G@2|Bacteria,1VNFK@1239|Firmicutes,4HRTG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - HTH_16 HPHIIJEP_02807 224308.BSU33221 1.1e-170 476.0 COG0745@1|root,COG0745@2|Bacteria,1TX0Q@1239|Firmicutes,4HEF8@91061|Bacilli,1ZBAA@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yvrH - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_02808 224308.BSU33210 0.0 1137.0 COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,4HC66@91061|Bacilli,1ZATU@1386|Bacillus 91061|Bacilli T Histidine kinase yvrG - - - - - - - - - - - HATPase_c,HisKA HPHIIJEP_02809 224308.BSU33200 1.32e-219 604.0 COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,1ZAVX@1386|Bacillus 91061|Bacilli G SMP-30/Gluconolaconase/LRE-like region yvrE GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 - ko:K14274 ko00040,map00040 - R02427 RC00713 ko00000,ko00001,ko01000 - - - SGL HPHIIJEP_02810 224308.BSU33190 2.12e-181 505.0 COG1028@1|root,COG1028@2|Bacteria,1TPZN@1239|Firmicutes,4HBJ8@91061|Bacilli,1ZCYQ@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yvrD - - - - - - - - - - - adh_short,adh_short_C2 HPHIIJEP_02811 224308.BSU33180 2.45e-217 600.0 COG0614@1|root,COG0614@2|Bacteria,1TQV7@1239|Firmicutes,4HCF3@91061|Bacilli,1ZBF0@1386|Bacillus 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component btuF - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33180 Peripla_BP_2 HPHIIJEP_02812 224308.BSU33170 1.56e-235 650.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli,1ZD7V@1386|Bacillus 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily btuC - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - iYO844.BSU33170 FecCD HPHIIJEP_02813 224308.BSU33160 5.2e-309 843.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HA28@91061|Bacilli,1ZASR@1386|Bacillus 91061|Bacilli HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components yvrA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran,CbiZ HPHIIJEP_02814 224308.BSU33150 1.2e-129 369.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4HH26@91061|Bacilli,1ZCJ1@1386|Bacillus 91061|Bacilli S Adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans HPHIIJEP_02815 224308.BSU33140 6.23e-286 783.0 COG0477@1|root,COG2814@2|Bacteria,1UIYF@1239|Firmicutes,4ISX5@91061|Bacilli,1ZDQ7@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily yvqJ - - - - - - - - - - - MFS_1 HPHIIJEP_02816 224308.BSU33130 6.17e-82 243.0 COG4758@1|root,COG4758@2|Bacteria,1UA5E@1239|Firmicutes,4IKFV@91061|Bacilli,1ZGWI@1386|Bacillus 91061|Bacilli S membrane liaI - - ko:K11619 ko02020,map02020 M00754 - - ko00000,ko00001,ko00002 - - - - HPHIIJEP_02817 224308.BSU33120 9.94e-143 404.0 COG1842@1|root,COG1842@2|Bacteria,1V2MH@1239|Firmicutes,4HGD1@91061|Bacilli,1ZAR1@1386|Bacillus 91061|Bacilli KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription liaH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03969,ko:K11620 ko02020,map02020 M00754 - - ko00000,ko00001,ko00002 - - - PspA_IM30 HPHIIJEP_02818 224308.BSU33110 6.57e-178 499.0 COG3595@1|root,COG3595@2|Bacteria,1V94C@1239|Firmicutes,4HJYP@91061|Bacilli,1ZEE4@1386|Bacillus 91061|Bacilli S Putative adhesin liaG - - ko:K11621 ko02020,map02020 - - - ko00000,ko00001 - - - DUF4097 HPHIIJEP_02819 224308.BSU33100 7.65e-164 459.0 COG4758@1|root,COG4758@2|Bacteria,1V9PN@1239|Firmicutes,4HMCU@91061|Bacilli,1ZQ0N@1386|Bacillus 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF - - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 HPHIIJEP_02820 224308.BSU33090 3.34e-245 675.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,1ZB48@1386|Bacillus 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 HPHIIJEP_02821 224308.BSU33080 4.46e-139 394.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1ZAT4@1386|Bacillus 91061|Bacilli KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_02822 224308.BSU33070 3.05e-243 671.0 2DFTJ@1|root,2ZT3R@2|Bacteria,1V3HD@1239|Firmicutes,4HGX9@91061|Bacilli,1ZBN5@1386|Bacillus 91061|Bacilli S Spore germination B3/ GerAC like, C-terminal gerAC - - ko:K06290,ko:K06293,ko:K06312 - - - - ko00000 - - - Spore_GerAC HPHIIJEP_02823 224308.BSU33060 3.94e-251 690.0 COG0814@1|root,COG0814@2|Bacteria,1UI6P@1239|Firmicutes,4ISFP@91061|Bacilli,1ZS5H@1386|Bacillus 91061|Bacilli E Spore germination protein gerAB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06289,ko:K06292 - - - - ko00000,ko02000 2.A.3.9.1,2.A.3.9.2 - - Spore_permease HPHIIJEP_02824 224308.BSU33050 0.0 900.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HAH1@91061|Bacilli,1ZBEF@1386|Bacillus 91061|Bacilli EG Spore germination protein gerAA - - ko:K06288,ko:K06291,ko:K06310 - - - - ko00000 - - - GerA HPHIIJEP_02825 224308.BSU33049 4.48e-34 117.0 2BF37@1|root,328V9@2|Bacteria,1UB6J@1239|Firmicutes,4IMJ7@91061|Bacilli,1ZK9V@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3970) - - - - - - - - - - - - DUF3970 HPHIIJEP_02826 224308.BSU33040 0.0 904.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,1ZS23@1386|Bacillus 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 HPHIIJEP_02827 224308.BSU33030 3.06e-204 565.0 COG1309@1|root,COG1309@2|Bacteria,1UDHR@1239|Firmicutes,4HFAX@91061|Bacilli,1ZFND@1386|Bacillus 91061|Bacilli K Transcriptional regulator yuxN GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_02828 224308.BSU33020 0.0 865.0 COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TSCS@1239|Firmicutes,4HBPP@91061|Bacilli,1ZBVF@1386|Bacillus 91061|Bacilli T Histidine kinase cssS - 2.7.13.3 ko:K07650 ko02020,map02020 M00448 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA HPHIIJEP_02829 224308.BSU33010 2.23e-164 459.0 COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,4HBSB@91061|Bacilli,1ZBX5@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain cssR - - ko:K07770 ko02020,map02020 M00448 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_02830 224308.BSU33000 1.12e-304 833.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,1ZB6P@1386|Bacillus 91061|Bacilli O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain htrA - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 HPHIIJEP_02831 224308.BSU32990 2.15e-104 301.0 COG0783@1|root,COG0783@2|Bacteria,1VC7X@1239|Firmicutes,4HKH8@91061|Bacilli,1ZRSG@1386|Bacillus 91061|Bacilli P Ferritin-like domain fri - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin HPHIIJEP_02832 224308.BSU32980 4.49e-196 544.0 COG1028@1|root,COG1028@2|Bacteria,1UI3U@1239|Firmicutes,4ISCX@91061|Bacilli,1ZS7R@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yusZ - - - - - - - - - - - adh_short HPHIIJEP_02833 1051501.AYTL01000004_gene3670 0.0 1041.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,1ZCRR@1386|Bacillus 91061|Bacilli E COG1164 Oligoendopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N HPHIIJEP_02834 1051501.AYTL01000004_gene3671 3.48e-88 260.0 2EDM5@1|root,337H0@2|Bacteria,1VIIH@1239|Firmicutes,4HPCP@91061|Bacilli,1ZJFZ@1386|Bacillus 91061|Bacilli S YusW-like protein - - - - - - - - - - - - YusW HPHIIJEP_02835 224308.BSU32940 8.74e-196 543.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HADG@91061|Bacilli,1ZBMI@1386|Bacillus 91061|Bacilli HP ABC transporter yusV - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran HPHIIJEP_02836 224308.BSU32930 2.48e-62 191.0 2DPT3@1|root,3339Q@2|Bacteria,1VJ5A@1239|Firmicutes,4HP0F@91061|Bacilli,1ZIZE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2573) yusU - - - - - - - - - - - DUF2573 HPHIIJEP_02837 224308.BSU32920 8.07e-202 560.0 COG0583@1|root,COG0583@2|Bacteria,1UCV1@1239|Firmicutes,4HE6I@91061|Bacilli,1ZQ2G@1386|Bacillus 91061|Bacilli K LysR substrate binding domain gltR - - ko:K21959 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_02838 1051501.AYTL01000004_gene3675 1.22e-138 396.0 COG1028@1|root,COG1028@2|Bacteria,1V05R@1239|Firmicutes,4HDCM@91061|Bacilli,1ZB06@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family yusR - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 HPHIIJEP_02839 224308.BSU32890 4.86e-84 248.0 COG1942@1|root,COG1942@2|Bacteria,1VF8N@1239|Firmicutes,4HPG0@91061|Bacilli,1ZR2J@1386|Bacillus 91061|Bacilli S Tautomerase enzyme yusQ - - - - - - - - - - - Tautomerase_2 HPHIIJEP_02840 224308.BSU32880 0.0 1015.0 COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli,1ZS1D@1386|Bacillus 91061|Bacilli P Major facilitator superfamily yusP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_02841 224308.BSU32870 6.35e-98 285.0 COG1846@1|root,COG1846@2|Bacteria,1VEPU@1239|Firmicutes,4HPM1@91061|Bacilli,1ZIJW@1386|Bacillus 91061|Bacilli K Iron dependent repressor, N-terminal DNA binding domain yusO GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_02842 224308.BSU32860 8.66e-70 211.0 COG5577@1|root,COG5577@2|Bacteria,1V96G@1239|Firmicutes,4HK73@91061|Bacilli,1ZHVT@1386|Bacillus 91061|Bacilli M Coat F domain yusN - - - - - - - - - - - Coat_F HPHIIJEP_02843 224308.BSU32859 2.23e-54 169.0 2E37R@1|root,32Y7E@2|Bacteria,1VEJ6@1239|Firmicutes,4HNWR@91061|Bacilli,1ZIXG@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02844 224308.BSU32850 2.72e-208 577.0 COG0506@1|root,COG0506@2|Bacteria,1TQV3@1239|Firmicutes,4HAC1@91061|Bacilli,1ZB5G@1386|Bacillus 91061|Bacilli E Proline dehydrogenase fadM GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 - R10507 RC00083 ko00000,ko00001,ko01000 - - - Pro_dh HPHIIJEP_02845 1345697.M493_15660 1.11e-13 64.7 2EVX5@1|root,33PAU@2|Bacteria,1W2JM@1239|Firmicutes,4HSMC@91061|Bacilli,1WH0A@129337|Geobacillus 91061|Bacilli S YuzL-like protein - - - - - - - - - - - - YuzL HPHIIJEP_02846 224308.BSU32840 0.0 1536.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,1ZATV@1386|Bacillus 91061|Bacilli I 3-hydroxyacyl-CoA dehydrogenase fadN - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32840 3HCDH,3HCDH_N,ECH_1 HPHIIJEP_02847 224308.BSU32830 3.15e-277 758.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N HPHIIJEP_02848 224308.BSU32820 0.0 1134.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,1ZBUU@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase fadE - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HPHIIJEP_02849 224308.BSU32810 1.01e-83 246.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli,1ZH0I@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin HPHIIJEP_02850 224308.BSU32800 5.91e-85 250.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,1ZGG0@1386|Bacillus 91061|Bacilli E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate gcvH GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H HPHIIJEP_02851 224308.BSU32790 7.34e-54 168.0 2ET7S@1|root,33KRT@2|Bacteria,1VP54@1239|Firmicutes,4HRRC@91061|Bacilli,1ZIUE@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2553) yusG - - - - - - - - - - - DUF2553 HPHIIJEP_02852 224308.BSU32780 7.62e-97 282.0 COG1658@1|root,COG1658@2|Bacteria,1VBXW@1239|Firmicutes,4HKN4@91061|Bacilli,1ZH1R@1386|Bacillus 91061|Bacilli L COG1658 Small primase-like proteins (Toprim domain) yusF GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K07476 - - - - ko00000 - - - Toprim,Toprim_2 HPHIIJEP_02853 224308.BSU32770 2e-73 219.0 COG0526@1|root,COG0526@2|Bacteria,1VEVR@1239|Firmicutes,4HNM9@91061|Bacilli,1ZIVX@1386|Bacillus 91061|Bacilli CO Thioredoxin yusE GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin HPHIIJEP_02854 224308.BSU32760 1.53e-74 223.0 2CCFT@1|root,330P4@2|Bacteria,1VHK2@1239|Firmicutes,4HP1K@91061|Bacilli,1ZGVX@1386|Bacillus 91061|Bacilli S SCP-2 sterol transfer family yusD - - - - - - - - - - - SCP2 HPHIIJEP_02855 224308.BSU32750 2.15e-236 651.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,1ZAZX@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - iYO844.BSU32750 ABC_tran,NIL HPHIIJEP_02856 224308.BSU32740 6.5e-126 362.0 COG2011@1|root,COG2011@2|Bacteria,1TR59@1239|Firmicutes,4H9NA@91061|Bacilli,1ZCW0@1386|Bacillus 91061|Bacilli P COG2011 ABC-type metal ion transport system, permease component metI GO:0000101,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015821,GO:0015849,GO:0016020,GO:0042940,GO:0044464,GO:0046942,GO:0048473,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072348 - ko:K02069,ko:K02072 ko02010,map02010 M00211,M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24,9.B.25.1 - - BPD_transp_1 HPHIIJEP_02857 224308.BSU32730 5.86e-189 525.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HBK0@91061|Bacilli,1ZATZ@1386|Bacillus 91061|Bacilli P Belongs to the NlpA lipoprotein family metQ - - ko:K02072,ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 HPHIIJEP_02858 224308.BSU32720 1.56e-80 239.0 COG0599@1|root,COG0599@2|Bacteria,1V8W7@1239|Firmicutes,4HHDQ@91061|Bacilli,1ZGYY@1386|Bacillus 91061|Bacilli S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity yurZ - - - - - - - - - - - CMD HPHIIJEP_02859 224308.BSU32710 4.46e-182 507.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,1ZAW4@1386|Bacillus 91061|Bacilli O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran HPHIIJEP_02860 224308.BSU32700 6.1e-312 850.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,1ZATY@1386|Bacillus 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 HPHIIJEP_02861 224308.BSU32690 1.14e-298 814.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,1ZB79@1386|Bacillus 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 HPHIIJEP_02862 1051501.AYTL01000004_gene3700 6.26e-101 292.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,1ZFQ8@1386|Bacillus 91061|Bacilli C COG0822 NifU homolog involved in Fe-S cluster formation nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N HPHIIJEP_02863 1051501.AYTL01000004_gene3701 0.0 935.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,1ZCDS@1386|Bacillus 91061|Bacilli O FeS cluster assembly sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 HPHIIJEP_02864 1051501.AYTL01000004_gene3704 5.06e-86 253.0 COG0346@1|root,COG0346@2|Bacteria,1V48E@1239|Firmicutes,4HHUT@91061|Bacilli,1ZGA1@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yurT - - - - - - - - - - - Glyoxalase HPHIIJEP_02865 1051501.AYTL01000004_gene3705 3.35e-56 175.0 2ESBJ@1|root,33JWA@2|Bacteria,1VNSX@1239|Firmicutes,4HS9N@91061|Bacilli,1ZK4C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02867 224308.BSU32630 1.07e-263 723.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli,1ZBU6@1386|Bacillus 91061|Bacilli E COG0665 Glycine D-amino acid oxidases (deaminating) yurR GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO HPHIIJEP_02868 224308.BSU32620 1.2e-87 257.0 COG0322@1|root,COG0322@2|Bacteria,1V8E6@1239|Firmicutes,4HJHV@91061|Bacilli,1ZGGU@1386|Bacillus 91061|Bacilli L COG0322 Nuclease subunit of the excinuclease complex yurQ GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - - - - - - - - - - GIY-YIG HPHIIJEP_02869 224308.BSU32610 5.27e-235 646.0 COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,4HB2C@91061|Bacilli,1ZCTQ@1386|Bacillus 91061|Bacilli M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid frlB - - ko:K10708 - - R08125 RC00053,RC01805 ko00000,ko01000 - - - SIS HPHIIJEP_02870 224308.BSU32600 3.21e-304 829.0 COG1653@1|root,COG1653@2|Bacteria,1UY14@1239|Firmicutes,4HEMF@91061|Bacilli,1ZQ33@1386|Bacillus 91061|Bacilli G COG1653 ABC-type sugar transport system, periplasmic component yurO - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 HPHIIJEP_02871 224308.BSU32590 3.54e-199 553.0 COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,4HAEJ@91061|Bacilli,1ZDHY@1386|Bacillus 91061|Bacilli G Binding-protein-dependent transport system inner membrane component yurN GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 HPHIIJEP_02872 224308.BSU32580 1.94e-216 597.0 COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,4IQN9@91061|Bacilli,1ZRMC@1386|Bacillus 91061|Bacilli P COG0395 ABC-type sugar transport system, permease component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 HPHIIJEP_02873 224308.BSU32570 9.18e-207 571.0 COG0524@1|root,COG0524@2|Bacteria,1TSST@1239|Firmicutes,4HGU3@91061|Bacilli,1ZREX@1386|Bacillus 91061|Bacilli G pfkB family carbohydrate kinase - - 2.7.1.218 ko:K10710 - - R08124 RC00002,RC00017 ko00000,ko01000 - - - PfkB HPHIIJEP_02874 224308.BSU32560 8.71e-175 487.0 COG2188@1|root,COG2188@2|Bacteria,1TVMZ@1239|Firmicutes,4H9TD@91061|Bacilli,1ZCCZ@1386|Bacillus 91061|Bacilli K UTRA frlR1 - - ko:K03710,ko:K10711 - - - - ko00000,ko03000 - - - GntR,UTRA HPHIIJEP_02875 224308.BSU32550 4.89e-262 718.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,1ZBDW@1386|Bacillus 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 HPHIIJEP_02876 224308.BSU32540 8.91e-216 594.0 COG2356@1|root,COG2356@2|Bacteria,1U9GI@1239|Firmicutes,4IJKB@91061|Bacilli,1ZAYK@1386|Bacillus 91061|Bacilli L Ribonuclease bsn GO:0005575,GO:0005576 - - - - - - - - - - Endonuclease_1 HPHIIJEP_02877 224308.BSU32530 2.91e-295 806.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,4HAE4@91061|Bacilli,1ZB60@1386|Bacillus 91061|Bacilli E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases pucF GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0017144,GO:0034641,GO:0042737,GO:0043167,GO:0043169,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047652,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.9 ko:K02083 ko00230,ko01120,map00230,map01120 - R02423 RC00064 ko00000,ko00001,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28,Peptidase_M42 HPHIIJEP_02878 224308.BSU32520 1.16e-303 827.0 COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,4HBDW@91061|Bacilli,1ZC8E@1386|Bacillus 91061|Bacilli E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase pucG GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 HPHIIJEP_02879 224308.BSU32510 7.18e-234 644.0 COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4HEI3@91061|Bacilli,1ZD2G@1386|Bacillus 91061|Bacilli O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family pucA - 1.17.1.4 ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - XdhC_C,XdhC_CoxI HPHIIJEP_02880 224308.BSU32500 4.18e-141 399.0 COG2068@1|root,COG2068@2|Bacteria,1VA0B@1239|Firmicutes,4HMD3@91061|Bacilli,1ZI29@1386|Bacillus 91061|Bacilli S MobA-like NTP transferase domain pucB - 1.17.1.4,2.7.7.76 ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 M00546 R01768,R02103,R11582 RC00143 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_3 HPHIIJEP_02881 224308.BSU32490 1.01e-186 520.0 COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,4HJ3P@91061|Bacilli,1ZG3A@1386|Bacillus 91061|Bacilli C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs pucC - 1.17.1.4,1.2.5.3 ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - - CO_deh_flav_C,FAD_binding_5 HPHIIJEP_02882 224308.BSU32480 0.0 1452.0 COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,1ZC08@1386|Bacillus 91061|Bacilli C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs pucD - 1.17.1.4 ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32480 Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 HPHIIJEP_02883 224308.BSU32470 1.99e-121 346.0 COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4HINQ@91061|Bacilli,1ZGEA@1386|Bacillus 91061|Bacilli C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs - - 1.17.1.4,1.2.5.3 ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103,R11168 RC00143,RC02800 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32470 Fer2,Fer2_2 HPHIIJEP_02884 221109.22777071 0.000154 41.2 2DRND@1|root,33CCV@2|Bacteria,1VNPA@1239|Firmicutes,4HR66@91061|Bacilli,23MAQ@182709|Oceanobacillus 91061|Bacilli S Protein of unknown function (Tiny_TM_bacill) - - - - - - - - - - - - Tiny_TM_bacill HPHIIJEP_02885 224308.BSU32460 2.09e-72 218.0 COG2351@1|root,COG2351@2|Bacteria,1VATV@1239|Firmicutes,4HKI8@91061|Bacilli,1ZHYV@1386|Bacillus 91061|Bacilli S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily pucM GO:0003674,GO:0005488,GO:0005515,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17 ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R06601 RC03393 ko00000,ko00001,ko00002,ko01000,ko02000 9.B.35.1.2,9.B.35.2 - - Transthyretin HPHIIJEP_02886 224308.BSU32450 0.0 962.0 COG3195@1|root,COG3648@1|root,COG3195@2|Bacteria,COG3648@2|Bacteria,1UY6S@1239|Firmicutes,4HAQX@91061|Bacilli,1ZCAY@1386|Bacillus 91061|Bacilli Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin - - 1.7.3.3,4.1.1.97 ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 M00546 R02106,R06604,R07981 RC01551,RC02107,RC02551 ko00000,ko00001,ko00002,ko01000 - - - OHCU_decarbox,Uricase HPHIIJEP_02887 224308.BSU32440 2.73e-284 780.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus 91061|Bacilli F xanthine pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169,ko:K16170 - - - - ko00000,ko02000 2.A.40.3.1,2.A.40.3.2 - - Xan_ur_permease HPHIIJEP_02888 224308.BSU32430 3.27e-295 809.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZB4S@1386|Bacillus 91061|Bacilli F Permease family pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169,ko:K16170 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1,2.A.40.3.2 - - Xan_ur_permease HPHIIJEP_02889 224308.BSU32420 0.0 1033.0 COG2508@1|root,COG2508@2|Bacteria,1TRDF@1239|Firmicutes,4H9KC@91061|Bacilli,1ZCWF@1386|Bacillus 91061|Bacilli QT COG2508 Regulator of polyketide synthase expression pucR - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR HPHIIJEP_02890 224308.BSU32410 0.0 888.0 COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4HBNG@91061|Bacilli,1ZBUB@1386|Bacillus 91061|Bacilli F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring allB GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R02425 RC00680 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 HPHIIJEP_02891 224308.BSU32400 3.06e-79 235.0 2E0C4@1|root,32X51@2|Bacteria,1VCSV@1239|Firmicutes,4HNEN@91061|Bacilli,1ZI88@1386|Bacillus 91061|Bacilli - - yunG - - - - - - - - - - - - HPHIIJEP_02892 224308.BSU32390 4.26e-220 605.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,1ZATP@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 HPHIIJEP_02893 224308.BSU32380 6.51e-181 505.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus 91061|Bacilli S membrane transporter protein yunE - - ko:K07090 - - - - ko00000 - - - TauE HPHIIJEP_02894 224308.BSU32370 0.0 905.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,1ZCJ8@1386|Bacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos HPHIIJEP_02895 224308.BSU32360 1.39e-64 197.0 COG3377@1|root,COG3377@2|Bacteria,1VAP7@1239|Firmicutes,4HKBM@91061|Bacilli,1ZHYB@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1805) yunC - - - - - - - - - - - DUF1805 HPHIIJEP_02896 224308.BSU32350 3.49e-169 474.0 2B51H@1|root,31XUS@2|Bacteria,1V6KA@1239|Firmicutes,4HKBP@91061|Bacilli,1ZFY9@1386|Bacillus 91061|Bacilli S Sporulation protein YunB (Spo_YunB) yunB - - - - - - - - - - - Spore_YunB HPHIIJEP_02897 224308.BSU32340 2.66e-252 690.0 COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,4HC7V@91061|Bacilli,1ZAQT@1386|Bacillus 91061|Bacilli M Peptidase, M23 lytH - - ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 HPHIIJEP_02898 224308.BSU32330 1.37e-215 595.0 COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,4H9SW@91061|Bacilli,1ZB5D@1386|Bacillus 91061|Bacilli H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM HPHIIJEP_02899 224308.BSU32320 1.34e-144 408.0 2EHES@1|root,33B6Q@2|Bacteria,1VNN8@1239|Firmicutes,4HRDX@91061|Bacilli,1ZFFJ@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) yutC - - - - - - - - - - - Spore_YhcN_YlaJ HPHIIJEP_02900 1051501.AYTL01000004_gene3739 3.2e-63 192.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,1ZHY5@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yutD - - - - - - - - - - - DUF1027 HPHIIJEP_02901 224308.BSU32300 1.96e-98 286.0 COG2445@1|root,COG2445@2|Bacteria,1V6HM@1239|Firmicutes,4HITV@91061|Bacilli,1ZGY2@1386|Bacillus 91061|Bacilli S Protein of unknown function DUF86 yutE - - - - - - - - - - - DUF86 HPHIIJEP_02902 224308.BSU32290 3.69e-183 509.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,1ZB73@1386|Bacillus 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like HPHIIJEP_02903 224308.BSU32280 2.26e-101 294.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZFQE@1386|Bacillus 91061|Bacilli I COG1267 Phosphatidylglycerophosphatase A and related proteins yutG - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA HPHIIJEP_02904 224308.BSU32270 4.98e-252 690.0 COG2334@1|root,COG2334@2|Bacteria,1VEZ6@1239|Firmicutes,4HBAB@91061|Bacilli,1ZBAM@1386|Bacillus 91061|Bacilli S Spore coat protein yutH GO:0005575,GO:0005623,GO:0042601,GO:0042763,GO:0044464 - - - - - - - - - - - HPHIIJEP_02905 224308.BSU32260 2.76e-306 835.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,1ZAVJ@1386|Bacillus 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 HPHIIJEP_02906 224308.BSU32250 3.97e-252 692.0 COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,1ZB11@1386|Bacillus 91061|Bacilli E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine thrC GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU32250 PALP HPHIIJEP_02907 224308.BSU32240 2.57e-221 610.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus 91061|Bacilli E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N HPHIIJEP_02908 224308.BSU32230 0.0 1251.0 COG0823@1|root,COG1506@1|root,COG4946@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG4946@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,1ZB2Q@1386|Bacillus 91061|Bacilli EU peptidase yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 HPHIIJEP_02909 224308.BSU32220 1.26e-47 153.0 COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,1ZHTR@1386|Bacillus 91061|Bacilli O COG0694 Thioredoxin-like proteins and domains yutI - - - - - - - - - - - NifU HPHIIJEP_02910 224308.BSU32210 7.74e-74 221.0 COG4837@1|root,COG4837@2|Bacteria,1VA2D@1239|Firmicutes,4HKZN@91061|Bacilli,1ZI07@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuzD - - - - - - - - - - - DUF1462 HPHIIJEP_02911 224308.BSU32200 1.3e-252 692.0 COG1252@1|root,COG1252@2|Bacteria,1TPE6@1239|Firmicutes,4H9MY@91061|Bacilli,1ZC0V@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yutJ - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 HPHIIJEP_02912 224308.BSU32190 1.74e-52 164.0 COG4844@1|root,COG4844@2|Bacteria,1VFJJ@1239|Firmicutes,4HNQ8@91061|Bacilli,1ZHVJ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0349 family yuzB - - - - - - - - - - - DUF1450 HPHIIJEP_02913 224308.BSU32180 6.25e-270 741.0 COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,4HA8N@91061|Bacilli,1ZAW2@1386|Bacillus 91061|Bacilli F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family yutK GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - ko:K03317 - - - - ko00000 2.A.41 - iYO844.BSU32180 Gate,Nucleos_tra2_C,Nucleos_tra2_N HPHIIJEP_02914 224308.BSU32170 3.9e-208 575.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,1ZD98@1386|Bacillus 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase HPHIIJEP_02915 224308.BSU32160 6.81e-83 244.0 COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HIKA@91061|Bacilli,1ZQR6@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family erpA - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn HPHIIJEP_02916 224308.BSU32150 3.98e-115 330.0 COG0454@1|root,COG0456@2|Bacteria,1V1RG@1239|Firmicutes,4HFN7@91061|Bacilli,1ZDTF@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases paiA GO:0003674,GO:0003824,GO:0004145,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0043937,GO:0043939,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0065007 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 HPHIIJEP_02917 224308.BSU32140 6.7e-148 416.0 COG2808@1|root,COG2808@2|Bacteria,1UYCC@1239|Firmicutes,4HGV6@91061|Bacilli,1ZQZA@1386|Bacillus 91061|Bacilli K Putative FMN-binding domain paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 HPHIIJEP_02918 224308.BSU32130 5.26e-234 644.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,1ZCDA@1386|Bacillus 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH HPHIIJEP_02920 224308.BSU32110 1.16e-240 661.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,1ZCEZ@1386|Bacillus 91061|Bacilli C reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 HPHIIJEP_02921 224308.BSU32100 4.16e-301 820.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus 91061|Bacilli C NADH dehydrogenase yumB GO:0003674,GO:0003824,GO:0003955,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iYO844.BSU32100 Pyr_redox_2 HPHIIJEP_02922 224308.BSU32080 9.78e-47 152.0 2CDZ2@1|root,32RYS@2|Bacteria,1VABM@1239|Firmicutes,4HKKB@91061|Bacilli,1ZHT7@1386|Bacillus 91061|Bacilli S Putative membrane protein yuiB - - - - - - - - - - - YuiB HPHIIJEP_02923 224308.BSU32070 2.69e-150 423.0 COG3584@1|root,COG3584@2|Bacteria,1UYMN@1239|Firmicutes,4HIVQ@91061|Bacilli,1ZDD1@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiC - - - - - - - - - - - 3D HPHIIJEP_02924 224308.BSU32060 8.63e-102 295.0 COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,4HHA6@91061|Bacilli,1ZFKA@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuiD - - ko:K09775 - - - - ko00000 - - - DUF212 HPHIIJEP_02925 224308.BSU32050 0.0 967.0 COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4HAPW@91061|Bacilli,1ZBZU@1386|Bacillus 91061|Bacilli E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N HPHIIJEP_02926 224308.BSU32040 3.65e-279 768.0 COG2056@1|root,COG2056@2|Bacteria,1TSRY@1239|Firmicutes,4HBK6@91061|Bacilli,1ZB9I@1386|Bacillus 91061|Bacilli S antiporter yuiF - - ko:K07084 - - - - ko00000,ko02000 2.A.8.1.12 - iSB619.SA_RS04585 Na_H_antiport_2,Na_H_antiporter HPHIIJEP_02927 224308.BSU32030 4.81e-124 355.0 COG1268@1|root,COG1268@2|Bacteria,1TS7R@1239|Firmicutes,4HC1H@91061|Bacilli,1ZCIP@1386|Bacillus 91061|Bacilli S Biotin biosynthesis protein bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY HPHIIJEP_02928 224308.BSU32020 3.92e-156 436.0 COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,1ZD5R@1386|Bacillus 91061|Bacilli S Oxidoreductase molybdopterin binding domain yuiH - - - - - - - - - - - Oxidored_molyb HPHIIJEP_02929 224308.BSU32010 8.23e-209 577.0 COG2819@1|root,COG2819@2|Bacteria,1V0WQ@1239|Firmicutes,4HEAZ@91061|Bacilli,1ZGN9@1386|Bacillus 91061|Bacilli S Putative esterase eSD - - ko:K07017 - - - - ko00000 - - - Esterase HPHIIJEP_02930 224308.BSU32000 5.83e-178 496.0 COG1028@1|root,COG1028@2|Bacteria,1TRFM@1239|Firmicutes,4HG6Y@91061|Bacilli,1ZEGF@1386|Bacillus 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family dhbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.3.1.28 ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R01505 RC00534 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 HPHIIJEP_02931 224308.BSU31990 2.02e-288 787.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4HD3U@91061|Bacilli,1ZEF0@1386|Bacillus 91061|Bacilli HQ Isochorismate synthase dhbC - 5.4.4.2 ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind HPHIIJEP_02932 224308.BSU31980 0.0 1073.0 COG1021@1|root,COG1021@2|Bacteria,1VX0S@1239|Firmicutes,4HCTT@91061|Bacilli,1ZC29@1386|Bacillus 91061|Bacilli Q 2,3-dihydroxybenzoate-AMP ligase entE - 2.7.7.58,6.3.2.14 ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R07644 RC00162,RC03046 ko00000,ko00001,ko01000,ko01008 - - - AMP-binding,AMP-binding_C,Chorismate_bind HPHIIJEP_02933 224308.BSU31970 7.41e-227 624.0 COG1535@1|root,COG3433@1|root,COG1535@2|Bacteria,COG3433@2|Bacteria,1UYPM@1239|Firmicutes,4HCQX@91061|Bacilli,1ZDF4@1386|Bacillus 91061|Bacilli Q Isochorismatase family dhbB - 3.3.2.1,6.3.2.14 ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R03037,R07644 RC00162,RC00350,RC02148,RC03046 ko00000,ko00001,ko01000,ko01008 - - - Isochorismatase,PP-binding HPHIIJEP_02934 224308.BSU31960 0.0 4674.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,1ZB3S@1386|Bacillus 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dhbF - - ko:K04780 ko01053,map01053 - - - ko00000,ko00001,ko01008 - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase HPHIIJEP_02935 224308.BSU31959 2.02e-47 151.0 COG3251@1|root,COG3251@2|Bacteria,1VQAA@1239|Firmicutes,4HRE7@91061|Bacilli,1ZNVW@1386|Bacillus 91061|Bacilli S MbtH-like protein mbtH - - ko:K05375 ko00261,ko01130,map00261,map01130 M00736 R10880 RC00064,RC00141,RC03296,RC03297,RC03298 ko00000,ko00001,ko00002 - - - MbtH HPHIIJEP_02936 224308.BSU31945 1.2e-168 470.0 COG5634@1|root,COG5634@2|Bacteria,1UESK@1239|Firmicutes,4HESW@91061|Bacilli,1ZG7X@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2278) yukJ - - - - - - - - - - - DUF2278 HPHIIJEP_02937 224308.BSU31930 1.91e-260 715.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus 91061|Bacilli E Belongs to the AlaDH PNT family ald GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N HPHIIJEP_02938 224308.BSU31920 2.33e-289 791.0 COG2508@1|root,COG4465@1|root,COG2508@2|Bacteria,COG4465@2|Bacteria,1TRRH@1239|Firmicutes,4HDGP@91061|Bacilli,1ZB6S@1386|Bacillus 91061|Bacilli QT Transcriptional regulator yukF GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043934,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - - - - - - - - - - CodY,HTH_30 HPHIIJEP_02939 1051501.AYTL01000004_gene3776 3.93e-60 185.0 COG4842@1|root,COG4842@2|Bacteria,1VHZ4@1239|Firmicutes,4IRN2@91061|Bacilli,1ZRVT@1386|Bacillus 91061|Bacilli S Belongs to the WXG100 family yukE - - - - - - - - - - - WXG100 HPHIIJEP_02940 224308.BSU31900 1.93e-54 169.0 COG5417@1|root,COG5417@2|Bacteria,1VG9I@1239|Firmicutes,4HPXH@91061|Bacilli,1ZJ9E@1386|Bacillus 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukD yukD - - - - - - - - - - - YukD HPHIIJEP_02941 224308.BSU31890 8.62e-271 747.0 COG4499@1|root,COG4499@2|Bacteria,1UY6F@1239|Firmicutes,4H9W3@91061|Bacilli,1ZCXX@1386|Bacillus 91061|Bacilli S WXG100 protein secretion system (Wss), protein YukC essB - - - - - - - - - - - YukC HPHIIJEP_02942 224308.BSU31875 0.0 2941.0 COG0433@1|root,COG1674@1|root,COG0433@2|Bacteria,COG1674@2|Bacteria,1TRA4@1239|Firmicutes,4H9QM@91061|Bacilli,1ZDSN@1386|Bacillus 91061|Bacilli D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins essC - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FHA,FtsK_SpoIIIE,FtsK_SpoIIIE_N HPHIIJEP_02943 1051501.AYTL01000004_gene3781 0.0 1401.0 COG1511@1|root,COG1511@2|Bacteria,1TPQK@1239|Firmicutes,4IPYE@91061|Bacilli,1ZREW@1386|Bacillus 91061|Bacilli S type VII secretion protein EsaA yueB - - - - - - - - - - - - HPHIIJEP_02944 224308.BSU31850 1.78e-96 281.0 2CK53@1|root,33EWP@2|Bacteria,1VNC3@1239|Firmicutes,4HSK6@91061|Bacilli,1ZFZV@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5383) yueC - - - - - - - - - - - DUF5383 HPHIIJEP_02945 224308.BSU31840 4.12e-169 473.0 COG1028@1|root,COG1028@2|Bacteria,1V1Z9@1239|Firmicutes,4HCPI@91061|Bacilli,1ZFQF@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) yueD - 1.1.1.320 ko:K16216 - - - - ko00000,ko01000 - - - adh_short HPHIIJEP_02946 224308.BSU31830 1.91e-125 357.0 COG1418@1|root,COG1418@2|Bacteria,1V3UK@1239|Firmicutes,4HH7I@91061|Bacilli,1ZFMK@1386|Bacillus 91061|Bacilli S phosphohydrolase yueE - - ko:K06950 - - - - ko00000 - - - HD HPHIIJEP_02947 720555.BATR1942_13755 8.4e-33 115.0 2EFV8@1|root,339ME@2|Bacteria,1VKCB@1239|Firmicutes,4HRFC@91061|Bacilli,1ZIX7@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2642) - - - - - - - - - - - - DUF2642 HPHIIJEP_02948 224308.BSU31810 2.21e-90 264.0 COG5428@1|root,30DFU@2|Bacteria,1UB8Y@1239|Firmicutes,4IMMP@91061|Bacilli,1ZKFQ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2283) - - - - - - - - - - - - DUF2283 HPHIIJEP_02949 224308.BSU31800 1.35e-244 674.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus 91061|Bacilli S transporter activity yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport HPHIIJEP_02950 224308.BSU31790 7.15e-43 140.0 2ASBM@1|root,31HQV@2|Bacteria,1UAM1@1239|Firmicutes,4IKZP@91061|Bacilli,1ZIHU@1386|Bacillus 91061|Bacilli S Spore germination protein gerPA/gerPF yueG - - ko:K06299 - - - - ko00000 - - - gerPA HPHIIJEP_02951 224308.BSU31780 1.34e-51 162.0 2EGG3@1|root,33A84@2|Bacteria,1VM9Y@1239|Firmicutes,4HR8J@91061|Bacilli,1ZJ1B@1386|Bacillus 91061|Bacilli S YueH-like protein yueH - - - - - - - - - - - YueH HPHIIJEP_02952 224308.BSU31770 3.64e-86 254.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HM3G@91061|Bacilli,1ZRYW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 HPHIIJEP_02953 224308.BSU31760 6.6e-134 379.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,1ZBY3@1386|Bacillus 91061|Bacilli Q COG1335 Amidases related to nicotinamidase pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - Isochorismatase HPHIIJEP_02954 224308.BSU31750 0.0 941.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,1ZCGY@1386|Bacillus 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - iYO844.BSU31750 NAPRTase HPHIIJEP_02955 224308.BSU31740 2.92e-298 813.0 COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,4HD4Q@91061|Bacilli,1ZDNG@1386|Bacillus 91061|Bacilli T signal transduction protein containing EAL and modified HD-GYP domains yuxH - - - - - - - - - - - EAL,HDOD HPHIIJEP_02956 1384049.CD29_07665 8.73e-09 55.8 2E2ZD@1|root,32Y01@2|Bacteria,1VHQD@1239|Firmicutes,4HNXI@91061|Bacilli,3IYR6@400634|Lysinibacillus 91061|Bacilli - - yuzC - - - - - - - - - - - - HPHIIJEP_02957 1274524.BSONL12_14624 6.29e-10 55.1 2BH1T@1|root,32B28@2|Bacteria,1UB34@1239|Firmicutes,4IMFU@91061|Bacilli,1ZK2F@1386|Bacillus 91061|Bacilli S DegQ (SacQ) family - - - - - - - - - - - - DegQ HPHIIJEP_02958 1051501.AYTL01000004_gene3795 7.01e-183 512.0 COG0142@1|root,COG0142@2|Bacteria,1V2BA@1239|Firmicutes,4HITP@91061|Bacilli,1ZRU4@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family comQ - - ko:K02251 ko02024,map02024 - - - ko00000,ko00001,ko02044 - - - polyprenyl_synt HPHIIJEP_02960 326423.RBAM_028770 0.0 928.0 COG4585@1|root,COG4585@2|Bacteria,1UBX4@1239|Firmicutes,4HCU8@91061|Bacilli,1ZDCQ@1386|Bacillus 91061|Bacilli T Histidine kinase comP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07680 ko02020,ko02024,map02020,map02024 M00476 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3,PAS_3 HPHIIJEP_02961 224308.BSU31680 2.06e-150 423.0 COG2197@1|root,COG2197@2|Bacteria,1V2KZ@1239|Firmicutes,4HCF0@91061|Bacilli,1ZH4R@1386|Bacillus 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain comA - - ko:K07691 ko02020,ko02024,map02020,map02024 M00476 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_02962 224308.BSU31670 7.81e-83 245.0 COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli,1ZGY5@1386|Bacillus 91061|Bacilli Q protein, possibly involved in aromatic compounds catabolism yuxO - - - - - - - - - - - 4HBT HPHIIJEP_02963 224308.BSU31660 8.49e-79 234.0 COG1320@1|root,COG1320@2|Bacteria,1VABT@1239|Firmicutes,4HKX5@91061|Bacilli,1ZHVK@1386|Bacillus 91061|Bacilli P COG1320 Multisubunit Na H antiporter, MnhG subunit mrpG - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iYO844.BSU31660 PhaG_MnhG_YufB HPHIIJEP_02964 224308.BSU31650 2.23e-51 163.0 COG2212@1|root,COG2212@2|Bacteria,1VFB4@1239|Firmicutes,4HNQY@91061|Bacilli,1ZI42@1386|Bacillus 91061|Bacilli P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpF - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iYO844.BSU31650 MrpF_PhaF HPHIIJEP_02965 224308.BSU31640 2.12e-102 297.0 COG1863@1|root,COG1863@2|Bacteria,1V52M@1239|Firmicutes,4HI4G@91061|Bacilli,1ZGAK@1386|Bacillus 91061|Bacilli P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpE - - ko:K05569 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MNHE HPHIIJEP_02966 224308.BSU31630 0.0 903.0 COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli,1ZB2A@1386|Bacillus 91061|Bacilli CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpD GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - iSB619.SA_RS04615 Proton_antipo_M HPHIIJEP_02967 224308.BSU31620 1.72e-66 202.0 COG1006@1|root,COG1006@2|Bacteria,1V7CR@1239|Firmicutes,4HJHX@91061|Bacilli,1ZH1G@1386|Bacillus 91061|Bacilli P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpC - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 HPHIIJEP_02968 224308.BSU31610 7.66e-91 266.0 COG2111@1|root,COG2111@2|Bacteria,1V3VF@1239|Firmicutes,4HHAN@91061|Bacilli,1ZHC0@1386|Bacillus 91061|Bacilli P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali mrpB - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB HPHIIJEP_02969 224308.BSU31600 0.0 1491.0 COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,1ZAZ0@1386|Bacillus 91061|Bacilli CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit mrpA GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - ko:K05565 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040,Proton_antipo_M,Proton_antipo_N HPHIIJEP_02970 720555.BATR1942_13645 1.73e-22 88.6 2ASDS@1|root,31HT9@2|Bacteria,1UAMP@1239|Firmicutes,4IM09@91061|Bacilli,1ZIKJ@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_02971 224308.BSU31580 7.99e-309 843.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,1ZC12@1386|Bacillus 91061|Bacilli C COG3493 Na citrate symporter malP - - ko:K11616 ko02020,map02020 - - - ko00000,ko00001 2.A.24.2 - - 2HCT HPHIIJEP_02972 224308.BSU31570 1.71e-215 596.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli,1ZAYF@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 HPHIIJEP_02973 224308.BSU31560 2.14e-235 649.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,1ZCTP@1386|Bacillus 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufP GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 HPHIIJEP_02974 224308.BSU31550 0.0 964.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,1ZS12@1386|Bacillus 91061|Bacilli S ABC transporter, ATP-binding protein yufO - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran HPHIIJEP_02975 224308.BSU31540 1.49e-252 693.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli,1ZBS3@1386|Bacillus 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp HPHIIJEP_02976 224308.BSU31530 3.26e-162 454.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,1ZFRB@1386|Bacillus 91061|Bacilli T COG4565 Response regulator of citrate malate metabolism dcuR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg HPHIIJEP_02977 224308.BSU31520 0.0 1013.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase regulating citrate malate metabolism malK - 2.7.13.3 ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 M00487,M00489,M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 HPHIIJEP_02978 224308.BSU31510 4.19e-113 326.0 2CIBU@1|root,30GF5@2|Bacteria,1V4EG@1239|Firmicutes,4HH80@91061|Bacilli,1ZGKU@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5366) yufK - - - - - - - - - - - DUF5366 HPHIIJEP_02979 224308.BSU31500 2.24e-96 280.0 COG3011@1|root,COG3011@2|Bacteria,1V7DJ@1239|Firmicutes,4HIUD@91061|Bacilli,1ZH0A@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuxK - - - - - - - - - - - DUF393 HPHIIJEP_02980 224308.BSU31490 0.0 1239.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4HBBB@91061|Bacilli,1ZCKA@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpD - 2.4.1.129,3.4.16.4 ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase HPHIIJEP_02981 224308.BSU31480 8.9e-242 667.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,1ZBN7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yuxJ - - - - - - - - - - - MFS_1,Sugar_tr HPHIIJEP_02983 224308.BSU31470 8.49e-150 421.0 COG5018@1|root,COG5018@2|Bacteria,1V7QB@1239|Firmicutes,4IRTF@91061|Bacilli,1ZRXX@1386|Bacillus 91061|Bacilli L the KinA pathway to sporulation kapD - - ko:K06348 - - - - ko00000 - - - RNase_T HPHIIJEP_02984 224308.BSU31460 2.49e-91 266.0 2DNAX@1|root,32UIM@2|Bacteria,1VATB@1239|Firmicutes,4HKG4@91061|Bacilli,1ZGXU@1386|Bacillus 91061|Bacilli G Kinase associated protein B kapB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06347 ko02020,map02020 - - - ko00000,ko00001 - - - KapB HPHIIJEP_02985 224308.BSU31450 3.04e-296 810.0 COG0642@1|root,COG2205@2|Bacteria,1V0MW@1239|Firmicutes,4HEZ5@91061|Bacilli,1ZS1T@1386|Bacillus 91061|Bacilli T Histidine kinase kinB2 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007,GO:0071944 2.7.13.3 ko:K07697 ko02020,map02020 M00485 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,HATPase_c,HisKA HPHIIJEP_02986 224308.BSU31440 1.16e-286 782.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_02987 224308.BSU31430 1.58e-54 170.0 2EACT@1|root,334GP@2|Bacteria,1VJJM@1239|Firmicutes,4HQ2Z@91061|Bacilli,1ZJ49@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1871) yugE - - - - - - - - - - - DUF1871 HPHIIJEP_02988 224308.BSU31420 1.11e-197 547.0 COG2267@1|root,COG2267@2|Bacteria,1TP59@1239|Firmicutes,4HEFN@91061|Bacilli,1ZBTQ@1386|Bacillus 91061|Bacilli I Hydrolase yugF GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 HPHIIJEP_02989 224308.BSU31410 6.74e-112 322.0 COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,4HH9K@91061|Bacilli,1ZFM5@1386|Bacillus 91061|Bacilli K Transcriptional regulator alaR - - - - - - - - - - - AsnC_trans_reg,HTH_24 HPHIIJEP_02990 224308.BSU31400 2.21e-254 699.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZAWQ@1386|Bacillus 91061|Bacilli E Aminotransferase yugH - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_02991 224308.BSU31390 5e-83 246.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,1ZHK5@1386|Bacillus 91061|Bacilli J RNA binding protein (contains ribosomal protein S1 domain) yugI - - ko:K07570,ko:K07571 - - - - ko00000 - - - S1 HPHIIJEP_02992 224308.BSU31380 2.21e-46 149.0 COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,4HP56@91061|Bacilli,1ZHUV@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF378) yuzA - - ko:K09779 - - - - ko00000 - - - DUF378 HPHIIJEP_02993 224308.BSU31370 8.16e-287 782.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,1ZBKF@1386|Bacillus 91061|Bacilli C oxidoreductases, Fe-dependent alcohol dehydrogenase family yugJ - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH HPHIIJEP_02994 224308.BSU31360 5.56e-291 793.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,1ZDAC@1386|Bacillus 91061|Bacilli C Dehydrogenase yugK - - ko:K19955 - - - - ko00000,ko01000 - - - Fe-ADH HPHIIJEP_02995 224308.BSU31350 0.0 900.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,1ZB6B@1386|Bacillus 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI HPHIIJEP_02997 224308.BSU31330 4.22e-95 276.0 2E71A@1|root,331JZ@2|Bacteria,1VG6F@1239|Firmicutes,4HNSV@91061|Bacilli,1ZHXR@1386|Bacillus 91061|Bacilli S YugN-like family yugN - - - - - - - - - - - YugN HPHIIJEP_02998 224308.BSU31322 3.56e-233 642.0 COG1226@1|root,COG1226@2|Bacteria,1TS7X@1239|Firmicutes,4HCIB@91061|Bacilli,1ZCD3@1386|Bacillus 91061|Bacilli P COG1226 Kef-type K transport systems yugO - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2,TrkA_N HPHIIJEP_02999 224308.BSU31321 5.01e-69 209.0 2EEW1@1|root,338PF@2|Bacteria,1VIRW@1239|Firmicutes,4HP92@91061|Bacilli,1ZJ73@1386|Bacillus 91061|Bacilli S Membrane-integrating protein Mistic mstX - - - - - - - - - - - Mistic HPHIIJEP_03000 224308.BSU31319 1.58e-50 160.0 29RVY@1|root,30D00@2|Bacteria,1UAMN@1239|Firmicutes,4IM08@91061|Bacilli,1ZIKF@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03001 224308.BSU31310 4.8e-150 423.0 COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,4HB8Z@91061|Bacilli,1ZD1M@1386|Bacillus 91061|Bacilli S Zn-dependent protease yugP - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 HPHIIJEP_03002 224308.BSU31300 4.36e-301 822.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yugS - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HPHIIJEP_03003 224308.BSU31290 0.0 1156.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,1ZASC@1386|Bacillus 91061|Bacilli G COG0366 Glycosidases yugT - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 iSB619.SA_RS07580 Alpha-amylase,Malt_amylase_C HPHIIJEP_03004 224308.BSU31280 2.11e-94 275.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4HI2R@91061|Bacilli,1ZGBA@1386|Bacillus 91061|Bacilli S Uncharacterised protein family UPF0047 yugU - - - - - - - - - - - UPF0047 HPHIIJEP_03005 720555.BATR1942_13465 5e-48 154.0 2E9DY@1|root,333MH@2|Bacteria,1VEUX@1239|Firmicutes,4HPGE@91061|Bacilli,1ZITW@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03006 224308.BSU31270 1.45e-179 499.0 arCOG13259@1|root,2Z8C5@2|Bacteria,1V23R@1239|Firmicutes,4HB9U@91061|Bacilli,1ZG1S@1386|Bacillus 91061|Bacilli H Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links tgl GO:0000003,GO:0003674,GO:0003810,GO:0003824,GO:0008150,GO:0016740,GO:0016746,GO:0016755,GO:0019954,GO:0030436,GO:0032502,GO:0043934,GO:0140096 2.3.2.13 ko:K00686 - - - - ko00000,ko01000 - - - - HPHIIJEP_03007 224308.BSU31260 0.0 894.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 HPHIIJEP_03008 224308.BSU31250 6.34e-300 838.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 HPHIIJEP_03009 224308.BSU31240 0.0 1094.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 HPHIIJEP_03010 224308.BSU31230 0.0 906.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZBEA@1386|Bacillus 91061|Bacilli NT chemotaxis protein mcpA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,dCache_1 HPHIIJEP_03011 224308.BSU31220 1.16e-19 87.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli,1ZC3P@1386|Bacillus 91061|Bacilli IQ Class II Aldolase and Adducin N-terminal domain yuxG - - - - - - - - - - - Aldolase_II,adh_short_C2 HPHIIJEP_03012 224308.BSU31220 0.0 1286.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli,1ZC3P@1386|Bacillus 91061|Bacilli IQ Class II Aldolase and Adducin N-terminal domain yuxG - - - - - - - - - - - Aldolase_II,adh_short_C2 HPHIIJEP_03013 224308.BSU31210 1.42e-172 483.0 COG1349@1|root,COG1349@2|Bacteria,1TSHY@1239|Firmicutes,4HD6Y@91061|Bacilli,1ZCCE@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism yulB - - ko:K02530,ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR HPHIIJEP_03014 224308.BSU31200 0.0 958.0 COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,4HB5X@91061|Bacilli,1ZAQ8@1386|Bacillus 91061|Bacilli G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate rhaB GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5 ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R03014 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N HPHIIJEP_03015 224308.BSU31190 2.86e-72 216.0 COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,4HM5P@91061|Bacilli,1ZGZB@1386|Bacillus 91061|Bacilli G Involved in the anomeric conversion of L-rhamnose rhaM - 5.1.3.32 ko:K03534 - - R10819 RC00563 ko00000,ko01000 - - - rhaM HPHIIJEP_03016 224308.BSU31180 0.0 864.0 COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,4HBQP@91061|Bacilli,1ZQ7E@1386|Bacillus 91061|Bacilli G Belongs to the rhamnose isomerase family rhaA GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5,5.3.1.14 ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R02437,R03014 RC00002,RC00017,RC00434 ko00000,ko00001,ko01000 - - - RhaA HPHIIJEP_03017 224308.BSU31170 9.11e-236 648.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,1ZBUF@1386|Bacillus 91061|Bacilli S Oxidoreductase yulF GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114,GO:0102497 - ko:K22230 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA HPHIIJEP_03018 224308.BSU31160 8.95e-255 701.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZCDX@1386|Bacillus 91061|Bacilli S transporter activity yubA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport HPHIIJEP_03019 224308.BSU31150 1.73e-182 509.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,1ZD80@1386|Bacillus 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA HPHIIJEP_03021 224308.BSU31140 2.29e-112 322.0 COG5553@1|root,COG5553@2|Bacteria,1VFPC@1239|Firmicutes,4HPUH@91061|Bacilli,1ZFM7@1386|Bacillus 91061|Bacilli S Cysteine dioxygenase type I cdoA - 1.13.11.20 ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 - R00893 RC00404 ko00000,ko00001,ko01000 - - - CDO_I HPHIIJEP_03022 224308.BSU31130 0.0 952.0 COG0477@1|root,COG0477@2|Bacteria,1UIMH@1239|Firmicutes,4ISNI@91061|Bacilli,1ZFGU@1386|Bacillus 91061|Bacilli P Major Facilitator Superfamily yubD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 HPHIIJEP_03023 224308.BSU31120 2.18e-195 545.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,1ZJU6@1386|Bacillus 91061|Bacilli NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase,SH3_8 HPHIIJEP_03024 224308.BSU31110 3.31e-52 164.0 COG4682@1|root,COG4682@2|Bacteria,1V29F@1239|Firmicutes,4HMJX@91061|Bacilli,1ZR9T@1386|Bacillus 91061|Bacilli S yiaA/B two helix domain yubF GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033554,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - - - - - - - - - - YiaAB HPHIIJEP_03025 224308.BSU31100 4.17e-298 816.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,1ZBJ9@1386|Bacillus 91061|Bacilli P Potassium - - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH HPHIIJEP_03026 224308.BSU31090 1.76e-155 436.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,1ZC2N@1386|Bacillus 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N HPHIIJEP_03027 224308.BSU31080 5.83e-118 338.0 2974U@1|root,2ZUCW@2|Bacteria,1W4BH@1239|Firmicutes,4I1IR@91061|Bacilli,1ZFDP@1386|Bacillus 91061|Bacilli - - yuaB - - - - - - - - - - - - HPHIIJEP_03028 224308.BSU31070 2.39e-121 347.0 COG1510@1|root,COG1510@2|Bacteria,1V3E5@1239|Firmicutes,4HIEJ@91061|Bacilli,1ZGAI@1386|Bacillus 91061|Bacilli K Belongs to the GbsR family yuaC - - ko:K22109 - - - - ko00000,ko03000 - - - - HPHIIJEP_03029 224308.BSU31060 0.0 972.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gbsA - 1.2.1.8 ko:K00130 ko00260,ko01100,map00260,map01100 M00555 R02565,R02566 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_03030 224308.BSU31050 2.46e-291 795.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAPA@91061|Bacilli,1ZBBG@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase gbsB GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.1 ko:K11440 ko00260,ko01100,map00260,map01100 M00555 R08557,R08558 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Fe-ADH HPHIIJEP_03031 224308.BSU31040 1.66e-136 386.0 28NII@1|root,2ZBJY@2|Bacteria,1V8N9@1239|Firmicutes,4HVKD@91061|Bacilli,1ZHKN@1386|Bacillus 91061|Bacilli - - yuaD - - - - - - - - - - - - HPHIIJEP_03032 224308.BSU31030 1.95e-109 315.0 COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,1ZR7U@1386|Bacillus 91061|Bacilli S DinB superfamily yuaE - - - - - - - - - - - DinB_2 HPHIIJEP_03033 224308.BSU31020 1.68e-109 316.0 COG1585@1|root,COG1585@2|Bacteria,1V4S8@1239|Firmicutes,4HHUI@91061|Bacilli,1ZGPJ@1386|Bacillus 91061|Bacilli OU Membrane protein implicated in regulation of membrane protease activity yuaF - - - - - - - - - - - - HPHIIJEP_03034 224308.BSU31010 4.54e-258 720.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,1ZBTE@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yuaG - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot HPHIIJEP_03035 224308.BSU31000 1.4e-121 347.0 COG1247@1|root,COG1247@2|Bacteria,1VAAC@1239|Firmicutes,4HKUR@91061|Bacilli,1ZHWJ@1386|Bacillus 91061|Bacilli M FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,FR47 HPHIIJEP_03036 224308.BSU30990 5.08e-122 349.0 COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,4HFZJ@91061|Bacilli,1ZR59@1386|Bacillus 91061|Bacilli S Thiamine transporter protein (Thia_YuaJ) thiT - - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ HPHIIJEP_03037 1051501.AYTL01000008_gene1340 1.13e-53 168.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,1ZI92@1386|Bacillus 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - HPHIIJEP_03059 224308.BSU30980 0.0 1338.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,1ZCHU@1386|Bacillus 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 HPHIIJEP_03060 224308.BSU30970 9.9e-264 723.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,1ZCF2@1386|Bacillus 91061|Bacilli G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008878,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0070566,GO:0071704,GO:1901576 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase HPHIIJEP_03061 224308.BSU30960 3.05e-237 653.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,1ZBVM@1386|Bacillus 91061|Bacilli G Glucose-1-phosphate adenylyltransferase, GlgD subunit glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase HPHIIJEP_03062 224308.BSU30950 0.0 974.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,1ZDBA@1386|Bacillus 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 HPHIIJEP_03063 224308.BSU30940 0.0 1609.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,1ZCRF@1386|Bacillus 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase HPHIIJEP_03064 224308.BSU30930 1.33e-99 290.0 COG3476@1|root,COG3476@2|Bacteria,1VDNQ@1239|Firmicutes,4IRXH@91061|Bacilli,1ZHKT@1386|Bacillus 91061|Bacilli T membrane ytaB - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR HPHIIJEP_03065 224308.BSU30920 1.29e-260 713.0 COG2334@1|root,COG2334@2|Bacteria,1V12T@1239|Firmicutes,4IPYD@91061|Bacilli,1ZREV@1386|Bacillus 91061|Bacilli S Spore coat protein cotI - - ko:K06331 - - - - ko00000 - - - APH HPHIIJEP_03066 224308.BSU30910 1.01e-275 753.0 COG0438@1|root,COG0438@2|Bacteria,1TRRW@1239|Firmicutes,4HAFA@91061|Bacilli,1ZCKJ@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 cotSA GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K06338 - - - - ko00000 - - - Glyco_transf_4,Glycos_transf_1 HPHIIJEP_03067 224308.BSU30900 3.3e-261 714.0 COG2334@1|root,COG2334@2|Bacteria,1V035@1239|Firmicutes,4HEX5@91061|Bacilli,1ZBJZ@1386|Bacillus 91061|Bacilli S Seems to be required for the assembly of the CotSA protein in spores cotS - - ko:K06337 - - - - ko00000 - - - - HPHIIJEP_03069 224308.BSU30880 6.58e-294 802.0 COG0438@1|root,COG0438@2|Bacteria,1TSGH@1239|Firmicutes,4HDGK@91061|Bacilli,1ZPVP@1386|Bacillus 91061|Bacilli M Glycosyltransferase Family 4 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K06338 - - - - ko00000 - - - Glyco_transf_4,Glycos_transf_1 HPHIIJEP_03070 224308.BSU30870 4.81e-225 620.0 COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,4HAN7@91061|Bacilli,1ZQ48@1386|Bacillus 91061|Bacilli M NAD-dependent epimerase dehydratase ytcB - - - - - - - - - - - Epimerase,GDP_Man_Dehyd HPHIIJEP_03071 224308.BSU30860 4.59e-307 837.0 COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,4HADP@91061|Bacilli,1ZAP3@1386|Bacillus 91061|Bacilli M Belongs to the UDP-glucose GDP-mannose dehydrogenase family ytcA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N HPHIIJEP_03072 224308.BSU30850 2.22e-192 534.0 COG1210@1|root,COG1210@2|Bacteria,1VRS2@1239|Firmicutes,4HUKI@91061|Bacilli,1ZCZA@1386|Bacillus 91061|Bacilli M Nucleotidyl transferase ytdA - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase HPHIIJEP_03073 224308.BSU30840 8.68e-169 471.0 COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,1ZEEI@1386|Bacillus 91061|Bacilli T COG1734 DnaK suppressor protein yteA - - - - - - - - - - - zf-dskA_traR HPHIIJEP_03074 224308.BSU30830 0.0 942.0 COG1169@1|root,COG1169@2|Bacteria,1TSRT@1239|Firmicutes,4H9K8@91061|Bacilli,1ZB3V@1386|Bacillus 91061|Bacilli HQ Isochorismate synthase menF GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30830 Chorismate_bind HPHIIJEP_03075 224308.BSU30820 0.0 1162.0 COG1165@1|root,COG1165@2|Bacteria,1TRDB@1239|Firmicutes,4HC48@91061|Bacilli,1ZANU@1386|Bacillus 91061|Bacilli H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05085 TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N HPHIIJEP_03076 224308.BSU30810 9.85e-197 545.0 COG0596@1|root,COG0596@2|Bacteria,1TS4C@1239|Firmicutes,4HB6G@91061|Bacilli,1ZAU9@1386|Bacillus 91061|Bacilli S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) menH GO:0003674,GO:0003824,GO:0016787 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 HPHIIJEP_03077 224308.BSU30800 3.45e-200 553.0 COG0447@1|root,COG0447@2|Bacteria,1UHNU@1239|Firmicutes,4HAD0@91061|Bacilli,1ZB3B@1386|Bacillus 91061|Bacilli H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) menB GO:0003674,GO:0003824,GO:0005488,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:0071890,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 HPHIIJEP_03078 224308.BSU30790 0.0 943.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZB6H@1386|Bacillus 91061|Bacilli H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily menE - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding,AMP-binding_C HPHIIJEP_03079 224308.BSU30780 2.37e-271 742.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HBMX@91061|Bacilli,1ZBMS@1386|Bacillus 91061|Bacilli H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) menC GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30780 MR_MLE_C,MR_MLE_N HPHIIJEP_03080 224308.BSU30770 1.08e-216 598.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,1ZC5F@1386|Bacillus 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family troA - - ko:K11707 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA HPHIIJEP_03081 224308.BSU30760 9.74e-176 490.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli,1ZC67@1386|Bacillus 91061|Bacilli P 'COG1121 ABC-type Mn Zn transport systems, ATPase component' mntB - 3.6.3.35 ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 M00243,M00244,M00319,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.15 - iYO844.BSU30760 ABC_tran HPHIIJEP_03082 224308.BSU30750 2.38e-292 800.0 COG1108@1|root,COG1321@1|root,COG1108@2|Bacteria,COG1321@2|Bacteria,1TPZB@1239|Firmicutes,4HCDH@91061|Bacilli,1ZDBC@1386|Bacillus 91061|Bacilli P COG1108 ABC-type Mn2 Zn2 transport systems, permease components mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 M00318,M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15,3.A.1.15.6 - - ABC-3 HPHIIJEP_03083 224308.BSU30740 6.23e-190 530.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,1ZAY6@1386|Bacillus 91061|Bacilli P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components' mntD GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11709,ko:K19976 ko02010,map02010 M00319,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.15 - - ABC-3 HPHIIJEP_03084 224308.BSU30739 2.43e-34 117.0 2E3H2@1|root,32YFR@2|Bacteria,1VF0S@1239|Firmicutes,4HNTB@91061|Bacilli,1ZJ4H@1386|Bacillus 91061|Bacilli S Domain of Unknown Function (DUF1540) - - - - - - - - - - - - DUF1540 HPHIIJEP_03085 224308.BSU30720 9.47e-238 655.0 COG1294@1|root,COG1294@2|Bacteria,1TPYX@1239|Firmicutes,4HA9T@91061|Bacilli,1ZCH6@1386|Bacillus 91061|Bacilli C COG1294 Cytochrome bd-type quinol oxidase, subunit 2 ythB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II HPHIIJEP_03086 224308.BSU30710 7.51e-316 860.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,1ZBAG@1386|Bacillus 91061|Bacilli C oxidase, subunit ythA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I HPHIIJEP_03087 224308.BSU30700 5.02e-56 174.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,1ZHX3@1386|Bacillus 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 HPHIIJEP_03088 224308.BSU30690 1.27e-133 378.0 COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,4HFQA@91061|Bacilli,1ZB5T@1386|Bacillus 91061|Bacilli P Reversible hydration of carbon dioxide ytiB - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA HPHIIJEP_03089 224308.BSU30670 8.36e-113 323.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,1ZBSW@1386|Bacillus 91061|Bacilli T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS HPHIIJEP_03090 224308.BSU30660 4.78e-95 277.0 28PM4@1|root,2ZCA8@2|Bacteria,1V1PA@1239|Firmicutes,4HFNN@91061|Bacilli,1ZG8T@1386|Bacillus 91061|Bacilli S YtkA-like ytkA - - - - - - - - - - - PKD,YtkA HPHIIJEP_03092 224308.BSU30650 1.8e-99 288.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli,1ZGCM@1386|Bacillus 91061|Bacilli P Belongs to the Dps family dps GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin HPHIIJEP_03093 224308.BSU30640 3.2e-81 241.0 COG4824@1|root,COG4824@2|Bacteria,1UA5F@1239|Firmicutes,4IKFX@91061|Bacilli,1ZGWK@1386|Bacillus 91061|Bacilli S Bacteriophage holin family ytkC - - - - - - - - - - - Phage_holin_4_1 HPHIIJEP_03094 224308.BSU30630 4.47e-113 324.0 COG0494@1|root,COG0494@2|Bacteria,1V42H@1239|Firmicutes,4HH5W@91061|Bacilli,1ZGYP@1386|Bacillus 91061|Bacilli L Belongs to the Nudix hydrolase family ytkD - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX HPHIIJEP_03095 224308.BSU30620 1.32e-183 511.0 COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,4HARB@91061|Bacilli,1ZD96@1386|Bacillus 91061|Bacilli P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component ytlD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 HPHIIJEP_03096 224308.BSU30610 1.5e-184 513.0 COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,4HBZ6@91061|Bacilli,1ZC33@1386|Bacillus 91061|Bacilli P ABC transporter ytlC - 3.6.3.36 ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 M00188,M00435,M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4 - - ABC_tran HPHIIJEP_03097 224308.BSU30595 1.87e-240 661.0 COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,4HAB9@91061|Bacilli,1ZC0Z@1386|Bacillus 91061|Bacilli P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components ytlA GO:0003674,GO:0005215 - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1,NMT1_2 HPHIIJEP_03098 224308.BSU30580 3.86e-190 527.0 COG1506@1|root,COG1506@2|Bacteria,1U5SB@1239|Firmicutes,4HB1A@91061|Bacilli,1ZC9W@1386|Bacillus 91061|Bacilli E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases ytmA - - - - - - - - - - - Peptidase_S9 HPHIIJEP_03099 224308.BSU30570 2.85e-52 164.0 2EA0D@1|root,32SFQ@2|Bacteria,1VJ7K@1239|Firmicutes,4HPZ6@91061|Bacilli,1ZR94@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2584) ytmB - - - - - - - - - - - DUF2584 HPHIIJEP_03100 224308.BSU30560 0.0 1068.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,1ZCVN@1386|Bacillus 91061|Bacilli C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09060,iYO844.BSU30560 PEPCK_ATP HPHIIJEP_03101 224308.BSU30550 2.26e-286 782.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,1ZBHR@1386|Bacillus 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N HPHIIJEP_03102 224308.BSU30540 0.0 1286.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 HPHIIJEP_03103 224308.BSU30530 0.0 892.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases ytnA - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease HPHIIJEP_03104 224308.BSU30520 8.35e-88 261.0 COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,1ZBFS@1386|Bacillus 91061|Bacilli S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily ytoA - - - - - - - - - - - Hexapep HPHIIJEP_03105 224308.BSU30510 4.7e-192 532.0 COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,1ZBD1@1386|Bacillus 91061|Bacilli I Alpha beta hydrolase ytpA GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 HPHIIJEP_03106 224308.BSU30500 4.81e-276 753.0 2C5HJ@1|root,2Z812@2|Bacteria,1TQQ6@1239|Firmicutes,4HA3F@91061|Bacilli,1ZCGB@1386|Bacillus 91061|Bacilli S Tetraprenyl-beta-curcumene synthase ytpB - 4.2.3.130 ko:K16188 - - R10009 RC02994 ko00000,ko01000 - - - DUF2600 HPHIIJEP_03107 224308.BSU30490 1.31e-134 381.0 COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,4ISFT@91061|Bacilli,1ZS5P@1386|Bacillus 91061|Bacilli J Putative rRNA methylase ytqB - - - - - - - - - - - rRNA_methylase HPHIIJEP_03108 224308.BSU30480 4.74e-244 669.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,1ZBM1@1386|Bacillus 91061|Bacilli S Fe-S oxidoreductase ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C HPHIIJEP_03109 224308.BSU30470 1.27e-55 173.0 29JW2@1|root,306TD@2|Bacteria,1U0BH@1239|Firmicutes,4I9NA@91061|Bacilli,1ZISQ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2524) ytzC - - - - - - - - - - - DUF2524 HPHIIJEP_03111 224308.BSU30460 2.68e-87 256.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,1ZGQV@1386|Bacillus 91061|Bacilli K GntR family transcriptional regulator ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR HPHIIJEP_03112 224308.BSU30450 5.96e-207 572.0 COG1131@1|root,COG1131@2|Bacteria,1VYEA@1239|Firmicutes,4HXN2@91061|Bacilli,1ZPYY@1386|Bacillus 91061|Bacilli P ABC transporter, ATP-binding protein ytrB - - ko:K16921 ko02010,map02010 M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_03113 224308.BSU30440 2.58e-210 584.0 2EWYB@1|root,33Q9P@2|Bacteria,1VRDR@1239|Firmicutes,4HT25@91061|Bacilli,1ZS7Q@1386|Bacillus 91061|Bacilli P ABC-2 family transporter protein - - - ko:K16919 ko02010,map02010 M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - - HPHIIJEP_03114 720555.BATR1942_12985 6.47e-191 535.0 28RDX@1|root,2ZDT6@2|Bacteria,1W1HD@1239|Firmicutes,4I0VX@91061|Bacilli 91061|Bacilli - - - - - ko:K16919 ko02010,map02010 M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC2_membrane_5 HPHIIJEP_03115 224308.BSU30420 4.83e-162 454.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HCWT@91061|Bacilli,1ZPYX@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein ytrE - - ko:K16920 ko02010,map02010 M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_03116 224308.BSU30410 1.98e-296 811.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HDKX@91061|Bacilli,1ZE27@1386|Bacillus 91061|Bacilli V COG0577 ABC-type antimicrobial peptide transport system, permease component ytrF - - ko:K02004,ko:K16918 ko02010,map02010 M00258,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD HPHIIJEP_03117 224308.BSU30400 5.25e-166 464.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,1ZCP0@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 M00469,M00725,M00726,M00730,M00733,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_03118 224308.BSU30390 2.06e-235 648.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HC32@91061|Bacilli,1ZS7P@1386|Bacillus 91061|Bacilli T His Kinase A (phosphoacceptor) domain bceS - 2.7.13.3 ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 M00469,M00725,M00726,M00730,M00733,M00738 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 - - - HATPase_c HPHIIJEP_03119 224308.BSU30380 1.56e-178 497.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,1ZCDW@1386|Bacillus 91061|Bacilli V ABC transporter, ATP-binding protein bceA - - ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00258,M00314,M00730,M00732,M00737,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1,3.A.1.134.3,3.A.1.134.7 - - ABC_tran HPHIIJEP_03120 224308.BSU30370 0.0 1168.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,1ZBJC@1386|Bacillus 91061|Bacilli V ABC transporter (permease) bceB - - ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 M00314,M00730,M00732,M00737,M00738 - - ko00000,ko00001,ko00002,ko01504,ko02000 3.A.1.134.3,3.A.1.134.7 - - FtsX HPHIIJEP_03121 224308.BSU30360 9.19e-53 177.0 COG2433@1|root,COG2433@2|Bacteria,1VFAN@1239|Firmicutes,4HQ1M@91061|Bacilli,1ZDUX@1386|Bacillus 91061|Bacilli S Pfam Transposase IS66 yttA - - - - - - - - - - - LMBR1 HPHIIJEP_03122 224308.BSU30350 1.72e-268 737.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,1ZBPE@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yttB - - - - - - - - - - - MFS_1 HPHIIJEP_03123 224308.BSU30340 2.21e-182 508.0 COG1366@1|root,COG2202@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,1V4PP@1239|Firmicutes,4HER6@91061|Bacilli,1ZE0R@1386|Bacillus 91061|Bacilli T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) pfyP GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - - - - - - - - - - PAS_9,STAS HPHIIJEP_03124 1051501.AYTL01000030_gene3098 3.63e-72 217.0 28XZV@1|root,2ZJVM@2|Bacteria,1W4DK@1239|Firmicutes,4I02G@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF4257) ytvB - - - - - - - - - - - DUF4257 HPHIIJEP_03125 224308.BSU30320 0.0 1655.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,1ZARG@1386|Bacillus 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 HPHIIJEP_03126 224308.BSU30310 1.22e-68 207.0 COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZH5X@1386|Bacillus 91061|Bacilli P Sulfurtransferase ytwF - - - - - - - - - - - Rhodanese HPHIIJEP_03127 224308.BSU30300 0.0 872.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HCGH@91061|Bacilli,1ZQT1@1386|Bacillus 91061|Bacilli G Family 4 glycosyl hydrolase melA - 3.2.1.22 ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_4,Glyco_hydro_4C HPHIIJEP_03128 224308.BSU30290 7.65e-186 518.0 COG0395@1|root,COG0395@2|Bacteria,1TR8M@1239|Firmicutes,4HAKX@91061|Bacilli,1ZQ4Y@1386|Bacillus 91061|Bacilli P ABC transporter (permease) amyC - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 HPHIIJEP_03129 224308.BSU30280 1.66e-214 592.0 COG1175@1|root,COG1175@2|Bacteria,1TRA3@1239|Firmicutes,4HEA0@91061|Bacilli,1ZQ7U@1386|Bacillus 91061|Bacilli P ABC transporter amyD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 HPHIIJEP_03130 224308.BSU30270 1.43e-309 843.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,4HAH2@91061|Bacilli,1ZD76@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein msmE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 HPHIIJEP_03131 224308.BSU30260 4.37e-242 665.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,1ZD8J@1386|Bacillus 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_03132 224308.BSU30250 1.13e-219 605.0 COG1073@1|root,COG1073@2|Bacteria,1UYH0@1239|Firmicutes,4HE35@91061|Bacilli,1ZQKV@1386|Bacillus 91061|Bacilli S Acetyl xylan esterase (AXE1) - - - - - - - - - - - - - HPHIIJEP_03133 224308.BSU30240 2.73e-180 501.0 COG1424@1|root,COG1424@2|Bacteria,1V38Y@1239|Firmicutes,4HJME@91061|Bacilli,1ZEA6@1386|Bacillus 91061|Bacilli H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP bioW - 6.2.1.14 ko:K01906 ko00780,ko01100,map00780,map01100 M00577 R03209 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - BioW HPHIIJEP_03134 224308.BSU30230 0.0 893.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H9QK@91061|Bacilli,1ZR67@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor bioA - 2.6.1.105,2.6.1.62 ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231,R10699 RC00006,RC00062,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12705 Aminotran_3 HPHIIJEP_03135 224308.BSU30220 2.12e-274 751.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus 91061|Bacilli H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide bioF GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 M00123,M00573,M00577 R00371,R03210,R10124 RC00004,RC00039,RC00394,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS12695 Aminotran_1_2 HPHIIJEP_03136 224308.BSU30210 3.13e-158 444.0 COG0132@1|root,COG0132@2|Bacteria,1V7IE@1239|Firmicutes,4IRD4@91061|Bacilli,1ZRTE@1386|Bacillus 91061|Bacilli H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring bioD GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 HPHIIJEP_03137 224308.BSU30200 5.33e-243 667.0 COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,4HAGM@91061|Bacilli,1ZCAU@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU30200 BATS,Radical_SAM HPHIIJEP_03138 224308.BSU30190 4.5e-279 763.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 bioI GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006629,GO:0006706,GO:0006707,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016042,GO:0016053,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016713,GO:0017144,GO:0018130,GO:0019752,GO:0020037,GO:0032787,GO:0034641,GO:0036199,GO:0042364,GO:0042440,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046148,GO:0046164,GO:0046394,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.46,1.14.15.13 ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 HPHIIJEP_03139 224308.BSU30180 1.28e-177 495.0 COG0451@1|root,COG0451@2|Bacteria,1V0AK@1239|Firmicutes,4HQJU@91061|Bacilli,1ZEQA@1386|Bacillus 91061|Bacilli GM NAD dependent epimerase/dehydratase family ytbQ - 1.1.1.203,1.1.1.388 ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R10520,R10841,R10907 RC00066 ko00000,ko00001,ko00002,ko01000 - - - Epimerase HPHIIJEP_03140 1051501.AYTL01000030_gene3082 6.19e-193 537.0 COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,4HBG3@91061|Bacilli,1ZCUS@1386|Bacillus 91061|Bacilli G COG0395 ABC-type sugar transport system, permease component ytcP - - ko:K17320 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 HPHIIJEP_03141 224308.BSU30160 0.0 988.0 COG1653@1|root,COG1653@2|Bacteria,1TRD0@1239|Firmicutes,4HTV1@91061|Bacilli,1ZQXP@1386|Bacillus 91061|Bacilli G COG1653 ABC-type sugar transport system, periplasmic component - - - ko:K17318 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - SBP_bac_1,SBP_bac_8 HPHIIJEP_03142 224308.BSU30150 0.0 1488.0 COG2207@1|root,COG2207@2|Bacteria,1UY4J@1239|Firmicutes,4HE0E@91061|Bacilli,1ZCUV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ytdP GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - - - - - - - - - - HTH_18,dCache_1 HPHIIJEP_03143 224308.BSU30135 5.35e-220 608.0 COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,4HATZ@91061|Bacilli,1ZAQ3@1386|Bacillus 91061|Bacilli G COG4209 ABC-type polysaccharide transport system, permease component lplB13 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K17319 ko02010,map02010 M00603 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.29,3.A.1.1.9 - - BPD_transp_1 HPHIIJEP_03144 224308.BSU30120 3.95e-277 756.0 COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,4HDRZ@91061|Bacilli,1ZCCP@1386|Bacillus 91061|Bacilli G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins yteR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.172 ko:K15532 - - - - ko00000,ko01000 - GH105 - Glyco_hydro_88 HPHIIJEP_03145 224308.BSU30110 2.27e-92 271.0 COG1653@1|root,COG1653@2|Bacteria,1U9I7@1239|Firmicutes,4IJNU@91061|Bacilli,1ZCI0@1386|Bacillus 91061|Bacilli G transport yteS - - - - - - - - - - - - HPHIIJEP_03146 224308.BSU30100 6.02e-315 856.0 COG0673@1|root,COG0673@2|Bacteria,1TSUT@1239|Firmicutes,4HDBM@91061|Bacilli,1ZD0S@1386|Bacillus 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain yteT - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_03147 224308.BSU30090 3.66e-148 418.0 COG5578@1|root,COG5578@2|Bacteria,1V69Y@1239|Firmicutes,4HH89@91061|Bacilli,1ZGMC@1386|Bacillus 91061|Bacilli S Integral membrane protein yteU - - - - - - - - - - - DUF624 HPHIIJEP_03148 224308.BSU30080 2.14e-36 122.0 2EJ4P@1|root,33CVX@2|Bacteria,1VMH9@1239|Firmicutes,4HSGS@91061|Bacilli,1ZIVZ@1386|Bacillus 91061|Bacilli S Sporulation protein Cse60 yteV - - - - - - - - - - - Spore_Cse60 HPHIIJEP_03149 224308.BSU30070 0.0 978.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli,1ZBRN@1386|Bacillus 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - iYO844.BSU30070 BCCT HPHIIJEP_03150 224308.BSU30060 1.41e-293 801.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli,1ZAT3@1386|Bacillus 91061|Bacilli S HI0933-like protein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like HPHIIJEP_03151 224308.BSU30050 0.0 969.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,1ZBR9@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C HPHIIJEP_03152 224308.BSU30035 7.13e-168 469.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HPHIIJEP_03153 224308.BSU30020 4.46e-46 148.0 COG1349@1|root,COG1349@2|Bacteria,1VG5N@1239|Firmicutes,4HNPQ@91061|Bacilli,1ZHT3@1386|Bacillus 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism ytzE - - - - - - - - - - - HTH_DeoR HPHIIJEP_03154 224308.BSU30010 3.82e-166 464.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,1ZC0G@1386|Bacillus 91061|Bacilli V ABC transporter ythP - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran HPHIIJEP_03155 224308.BSU30000 2.89e-254 700.0 COG4473@1|root,COG4473@2|Bacteria,1V6RH@1239|Firmicutes,4HK0C@91061|Bacilli,1ZEVB@1386|Bacillus 91061|Bacilli U Bacterial ABC transporter protein EcsB ythQ - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB HPHIIJEP_03156 224308.BSU29990 7.02e-288 789.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1ZDJJ@1386|Bacillus 91061|Bacilli S permease pbuO - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease HPHIIJEP_03157 224308.BSU29980 0.0 931.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,1ZBI2@1386|Bacillus 91061|Bacilli E Dipeptidase ytjP - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 HPHIIJEP_03158 224308.BSU29970 3e-221 610.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZC73@1386|Bacillus 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family ytkP GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP HPHIIJEP_03159 224308.BSU29960 2.04e-128 365.0 COG1514@1|root,COG1514@2|Bacteria,1VCBK@1239|Firmicutes,4HM3V@91061|Bacilli,1ZHT8@1386|Bacillus 91061|Bacilli J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ytlP GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase HPHIIJEP_03160 224308.BSU29950 2.34e-210 582.0 28NSI@1|root,2ZB4U@2|Bacteria,1UZ00@1239|Firmicutes,4HDBT@91061|Bacilli,1ZDNP@1386|Bacillus 91061|Bacilli - - ytlQ - - - - - - - - - - - NERD HPHIIJEP_03161 224308.BSU29940 2.22e-231 635.0 COG1597@1|root,COG1597@2|Bacteria,1TUH3@1239|Firmicutes,4IR1U@91061|Bacilli,1ZRQM@1386|Bacillus 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat HPHIIJEP_03162 224308.BSU29930 0.0 1452.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,1ZC85@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amyX - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 HPHIIJEP_03163 1051501.AYTL01000030_gene3059 3.02e-192 533.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH HPHIIJEP_03164 224308.BSU29910 9.51e-61 186.0 2E43M@1|root,32YZY@2|Bacteria,1VAYB@1239|Firmicutes,4HM5I@91061|Bacilli,1ZQJD@1386|Bacillus 91061|Bacilli S YtzH-like protein ytzH - - - - - - - - - - - YtzH HPHIIJEP_03165 224308.BSU29900 1.25e-155 436.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,1ZAP2@1386|Bacillus 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 HPHIIJEP_03166 1051501.AYTL01000030_gene3056 1.06e-190 531.0 COG0491@1|root,COG0491@2|Bacteria,1TRED@1239|Firmicutes,4HAP2@91061|Bacilli,1ZAYX@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases ytnP - - - - - - - - - - - Lactamase_B HPHIIJEP_03167 224308.BSU29880 0.0 1122.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZD0I@1386|Bacillus 91061|Bacilli C Malate dehydrogenase malS GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006090,GO:0006108,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic HPHIIJEP_03168 224308.BSU29870 2.35e-67 204.0 COG5584@1|root,COG5584@2|Bacteria,1VEIQ@1239|Firmicutes,4HNS2@91061|Bacilli,1ZJ31@1386|Bacillus 91061|Bacilli S small secreted protein ytzB - - - - - - - - - - - PepSY HPHIIJEP_03169 224308.BSU29860 3.71e-261 715.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZAXE@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 HPHIIJEP_03170 224308.BSU29850 7.02e-103 297.0 28NR0@1|root,2ZBQD@2|Bacteria,1V1Z5@1239|Firmicutes,4HGAG@91061|Bacilli,1ZE4G@1386|Bacillus 91061|Bacilli S Nucleoside 2-deoxyribosyltransferase YtoQ ytoQ - - - - - - - - - - - Nuc_deoxyri_tr3 HPHIIJEP_03171 224308.BSU29840 3.17e-75 224.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,1ZHAS@1386|Bacillus 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin HPHIIJEP_03172 224308.BSU29830 1.02e-191 532.0 COG4848@1|root,COG4848@2|Bacteria,1TTBU@1239|Firmicutes,4HAD1@91061|Bacilli,1ZBQ7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0354 family ytpQ - - - - - - - - - - - DUF1444 HPHIIJEP_03173 224308.BSU29820 1.78e-140 397.0 COG0073@1|root,COG0073@2|Bacteria,1V3R1@1239|Firmicutes,4HHBI@91061|Bacilli,1ZD7F@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily ytpR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind HPHIIJEP_03174 224308.BSU29805 0.0 1634.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,1ZAYY@1386|Bacillus 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma HPHIIJEP_03175 224308.BSU29790 0.0 874.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,1ZB5U@1386|Bacillus 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M HPHIIJEP_03176 224308.BSU29780 1.67e-63 197.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,1ZGYS@1386|Bacillus 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 HPHIIJEP_03177 224308.BSU29770 3.17e-30 114.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,1ZEKS@1386|Bacillus 91061|Bacilli S COG4980 Gas vesicle protein ytxH - - - - - - - - - - - YtxH HPHIIJEP_03178 224308.BSU29760 2.23e-71 214.0 COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,1ZI6R@1386|Bacillus 91061|Bacilli O Protein of unknown function (DUF2847) ytxJ - - - - - - - - - - - DUF2847 HPHIIJEP_03179 224308.BSU29750 7.64e-250 686.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,1ZB0X@1386|Bacillus 91061|Bacilli E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate aroA - 2.5.1.54,5.4.99.5 ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R01826 RC00435,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2,DAHP_synth_1 HPHIIJEP_03180 224308.BSU29740 4.16e-235 647.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,1ZCFZ@1386|Bacillus 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_03181 224308.BSU29730 6.84e-187 520.0 COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,4HAXG@91061|Bacilli,1ZB8I@1386|Bacillus 91061|Bacilli N flagellar motor motP GO:0001539,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0040011,GO:0044425,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB HPHIIJEP_03182 224308.BSU29720 1.6e-161 453.0 COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus 91061|Bacilli N Flagellar motor protein ytxE - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA HPHIIJEP_03183 224308.BSU29710 1.81e-290 792.0 COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,1ZC2K@1386|Bacillus 91061|Bacilli BQ histone deacetylase acuC - - ko:K04768 - - - - ko00000 - - iYO844.BSU29710 Hist_deacetyl HPHIIJEP_03184 224308.BSU29700 1.24e-151 426.0 COG0517@1|root,COG0517@2|Bacteria,1V7SC@1239|Firmicutes,4HGJP@91061|Bacilli,1ZRPY@1386|Bacillus 91061|Bacilli S Domain in cystathionine beta-synthase and other proteins. acuB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - ko:K04767 - - - - ko00000 - - - ACT,CBS HPHIIJEP_03185 224308.BSU29690 3.46e-156 437.0 COG0454@1|root,COG0454@2|Bacteria,1TSEY@1239|Firmicutes,4HA1V@91061|Bacilli,1ZANI@1386|Bacillus 91061|Bacilli K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue acuA GO:0001101,GO:0003674,GO:0003824,GO:0006066,GO:0006355,GO:0006950,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009267,GO:0009605,GO:0009847,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010034,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016407,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019152,GO:0019219,GO:0019222,GO:0019751,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032502,GO:0033554,GO:0034077,GO:0034078,GO:0034311,GO:0034313,GO:0042149,GO:0042180,GO:0042182,GO:0042221,GO:0042594,GO:0042844,GO:0042846,GO:0043894,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045013,GO:0045014,GO:0045149,GO:0045150,GO:0045892,GO:0045934,GO:0045990,GO:0046015,GO:0046164,GO:0046174,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0061984,GO:0061985,GO:0061986,GO:0065007,GO:0070887,GO:0071229,GO:0071236,GO:0071310,GO:0071311,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1901700,GO:1901701,GO:1902652,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K04766 - - - - ko00000,ko01000 - - - Acetyltransf_1 HPHIIJEP_03186 224308.BSU29680 0.0 1164.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZBDX@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C HPHIIJEP_03187 224308.BSU29670 3.74e-303 827.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b HPHIIJEP_03189 224308.BSU29660 2.01e-141 399.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,1ZCEB@1386|Bacillus 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 HPHIIJEP_03190 224308.BSU29650 0.0 1112.0 COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TQ2X@1239|Firmicutes,4HA6T@91061|Bacilli,1ZCE7@1386|Bacillus 91061|Bacilli T COG2199 FOG GGDEF domain ytrP - - - - - - - - - - - GAF_2,GAF_3,GGDEF HPHIIJEP_03191 224308.BSU29640 1.13e-113 326.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,1ZFMG@1386|Bacillus 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 HPHIIJEP_03192 224308.BSU29630 1.2e-141 400.0 COG1309@1|root,COG1309@2|Bacteria,1V6TA@1239|Firmicutes,4HISQ@91061|Bacilli,1ZGRH@1386|Bacillus 91061|Bacilli K Transcriptional regulator yttP GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N HPHIIJEP_03193 224308.BSU29620 5.29e-198 548.0 COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,4H9P1@91061|Bacilli,1ZCA3@1386|Bacillus 91061|Bacilli E COG1387 Histidinol phosphatase and related hydrolases of the PHP family hisK GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP,PHP_C HPHIIJEP_03194 224308.BSU29610 0.0 984.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,1ZAWX@1386|Bacillus 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA HPHIIJEP_03195 224308.BSU29600 1.17e-304 832.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids braB GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans HPHIIJEP_03196 224308.BSU29590 1.3e-264 726.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,1ZBHY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 HPHIIJEP_03197 224308.BSU29580 6.26e-289 789.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,1ZBZY@1386|Bacillus 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI HPHIIJEP_03198 224308.BSU29570 2.12e-40 133.0 2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,4HNHZ@91061|Bacilli,1ZIWS@1386|Bacillus 91061|Bacilli S spore protein - - - ko:K06418,ko:K06419,ko:K06420 - - - - ko00000 - - - SASP HPHIIJEP_03199 224308.BSU29560 0.0 1045.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,1ZCDC@1386|Bacillus 91061|Bacilli I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases ytcI GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C HPHIIJEP_03200 224308.BSU29550 0.0 1070.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli,1ZBDY@1386|Bacillus 91061|Bacilli S amidohydrolase ytcJ - - - - - - - - - - - Amidohydro_3 HPHIIJEP_03201 224308.BSU29540 5.66e-188 522.0 COG0061@1|root,COG0061@2|Bacteria,1TRXB@1239|Firmicutes,4HCEW@91061|Bacilli,1ZB1S@1386|Bacillus 91061|Bacilli G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK2 - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase HPHIIJEP_03202 224308.BSU29530 2.05e-231 638.0 COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,1ZBTV@1386|Bacillus 91061|Bacilli OU signal peptide peptidase SppA sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 HPHIIJEP_03203 224308.BSU29520 2.36e-111 320.0 COG1714@1|root,COG1714@2|Bacteria,1VATS@1239|Firmicutes,4HKJ3@91061|Bacilli,1ZFC7@1386|Bacillus 91061|Bacilli S RDD family yteJ - - - - - - - - - - - RDD HPHIIJEP_03204 224308.BSU29510 8.34e-149 420.0 2E5MF@1|root,330CC@2|Bacteria,1VEG0@1239|Firmicutes,4HMVE@91061|Bacilli,1ZBQY@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2953) ytfI - - - - - - - - - - - DUF2953 HPHIIJEP_03205 224308.BSU29500 1.06e-94 277.0 COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,4HIG7@91061|Bacilli,1ZG9C@1386|Bacillus 91061|Bacilli S Sporulation protein YtfJ ytfJ - - - - - - - - - - - Spore_YtfJ HPHIIJEP_03206 224308.BSU29490 1.93e-116 333.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,1ZARA@1386|Bacillus 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin HPHIIJEP_03207 224308.BSU29480 3.78e-224 619.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,1ZBZ7@1386|Bacillus 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase HPHIIJEP_03208 224308.BSU29470 4.69e-281 768.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,1ZDDX@1386|Bacillus 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase HPHIIJEP_03209 224308.BSU29460 9.12e-112 322.0 COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,4HH5V@91061|Bacilli,1ZFK1@1386|Bacillus 91061|Bacilli H May be involved in the biosynthesis of molybdopterin moaB - 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth HPHIIJEP_03210 224308.BSU29450 4.3e-297 810.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth HPHIIJEP_03211 224308.BSU29440 0.0 913.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,1ZD3C@1386|Bacillus 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 HPHIIJEP_03213 224308.BSU29420 1.98e-182 507.0 COG1028@1|root,COG1028@2|Bacteria,1TSQV@1239|Firmicutes,4HB3U@91061|Bacilli,1ZC75@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) ytkK - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 HPHIIJEP_03214 224308.BSU29410 2.71e-166 464.0 COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,4HBM0@91061|Bacilli,1ZBI0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0173 family ytkL - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 HPHIIJEP_03215 224308.BSU29270 1.13e-308 842.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,1ZB1Q@1386|Bacillus 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 HPHIIJEP_03216 224308.BSU29260 3.57e-62 191.0 2E1U1@1|root,32X3Q@2|Bacteria,1VD0Y@1239|Firmicutes,4HNCK@91061|Bacilli,1ZHYC@1386|Bacillus 91061|Bacilli S YtpI-like protein ytpI - - - - - - - - - - - YtpI HPHIIJEP_03217 224308.BSU29250 1.24e-230 634.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,1ZB08@1386|Bacillus 91061|Bacilli S COG0618 Exopolyphosphatase-related proteins nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 HPHIIJEP_03218 224308.BSU29249 1.15e-39 131.0 2EK73@1|root,33DXG@2|Bacteria,1VJ98@1239|Firmicutes,4HNYT@91061|Bacilli,1ZIJ7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03219 224308.BSU29240 5.12e-112 322.0 2AV7G@1|root,31KY3@2|Bacteria,1V73K@1239|Firmicutes,4HJ3F@91061|Bacilli,1ZHIX@1386|Bacillus 91061|Bacilli - - ytrI - - - - - - - - - - - - HPHIIJEP_03220 224308.BSU29239 2.45e-75 225.0 2CBNY@1|root,330BE@2|Bacteria,1VGPH@1239|Firmicutes,4HNX7@91061|Bacilli,1ZH6P@1386|Bacillus 91061|Bacilli S Sporulation protein YtrH ytrH - - - - - - - - - - - Spore_YtrH HPHIIJEP_03221 224308.BSU29230 0.0 2169.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,1ZCIC@1386|Bacillus 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon HPHIIJEP_03222 224308.BSU29220 8.53e-287 784.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,1ZBAH@1386|Bacillus 91061|Bacilli C Malate dehydrogenase ytsJ - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic HPHIIJEP_03223 224308.BSU29210 1.46e-206 571.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,1ZB3M@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans HPHIIJEP_03224 224308.BSU29200 1.98e-233 642.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,1ZC5V@1386|Bacillus 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA HPHIIJEP_03225 224308.BSU29190 4.65e-229 630.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,1ZB3D@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK HPHIIJEP_03226 224308.BSU29180 0.0 1111.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,1ZCDT@1386|Bacillus 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C HPHIIJEP_03227 224308.BSU29170 3.16e-80 238.0 COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,4HNQ9@91061|Bacilli,1ZQRP@1386|Bacillus 91061|Bacilli S COG3030 Protein affecting phage T7 exclusion by the F plasmid fxsA - - ko:K07113 - - - - ko00000 - - - FxsA HPHIIJEP_03228 224308.BSU29160 2.73e-245 676.0 COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,4HC6G@91061|Bacilli,1ZBXK@1386|Bacillus 91061|Bacilli S sporulation integral membrane protein YtvI ytvI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport HPHIIJEP_03229 224308.BSU29150 9.38e-95 277.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4HINS@91061|Bacilli,1ZQTM@1386|Bacillus 91061|Bacilli S membrane ytwI - - - - - - - - - - - DUF441 HPHIIJEP_03230 224308.BSU29140 1.17e-267 733.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,1ZBAY@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt HPHIIJEP_03231 224308.BSU29130 9.27e-309 841.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli,1ZBWV@1386|Bacillus 91061|Bacilli C isocitrate icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh HPHIIJEP_03232 224308.BSU29120 1.04e-217 601.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,1ZC27@1386|Bacillus 91061|Bacilli C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N HPHIIJEP_03233 224308.BSU29110 3.27e-169 473.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,1ZBGS@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_03234 224308.BSU29100 0.0 1115.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,1ZC0T@1386|Bacillus 91061|Bacilli T Signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like HPHIIJEP_03235 224308.BSU29090 0.0 1695.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,1ZB6Y@1386|Bacillus 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A HPHIIJEP_03236 224308.BSU29080 4.73e-201 556.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,1ZCC9@1386|Bacillus 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS HPHIIJEP_03237 224308.BSU29070 1.68e-138 392.0 COG1971@1|root,COG1971@2|Bacteria,1V4BC@1239|Firmicutes,4HH29@91061|Bacilli,1ZCPR@1386|Bacillus 91061|Bacilli P Probably functions as a manganese efflux pump ytaF - - - - - - - - - - - Mntp HPHIIJEP_03238 224308.BSU29060 2.82e-126 360.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,1ZFSI@1386|Bacillus 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE HPHIIJEP_03239 224308.BSU29050 4.54e-205 566.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,1ZC55@1386|Bacillus 91061|Bacilli S reductase ytbE - - - - - - - - - - - Aldo_ket_red HPHIIJEP_03240 224308.BSU29040 3.37e-256 706.0 COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,4HAYB@91061|Bacilli,1ZQ77@1386|Bacillus 91061|Bacilli EGP -transporter ytbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K19577 - - - - ko00000,ko02000 2.A.1.2.65 - - MFS_1,Sugar_tr HPHIIJEP_03241 224308.BSU29030 1.15e-86 254.0 COG1733@1|root,COG1733@2|Bacteria,1V43K@1239|Firmicutes,4HH01@91061|Bacilli,1ZGIV@1386|Bacillus 91061|Bacilli K Transcriptional regulator ytcD - - - - - - - - - - - HxlR HPHIIJEP_03242 224308.BSU29020 1.73e-246 676.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapB GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016491,GO:0016620,GO:0016903,GO:0019318,GO:0019319,GO:0036094,GO:0043891,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N HPHIIJEP_03243 1051501.AYTL01000030_gene2978 2.42e-88 259.0 COG1586@1|root,COG1586@2|Bacteria,1V3U2@1239|Firmicutes,4HH1F@91061|Bacilli,1ZFPA@1386|Bacillus 91061|Bacilli E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine speH - 4.1.1.50 ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 M00034,M00133 R00178 RC00299 ko00000,ko00001,ko00002,ko01000 - - - AdoMet_dc HPHIIJEP_03244 224308.BSU29000 2.42e-105 304.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,1ZFS0@1386|Bacillus 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone HPHIIJEP_03245 224308.BSU28990 0.0 922.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,1ZBJY@1386|Bacillus 91061|Bacilli L Membrane attachment protein dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 HPHIIJEP_03246 224308.BSU28980 8.23e-219 604.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,1ZB6G@1386|Bacillus 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 HPHIIJEP_03247 224308.BSU28970 1.33e-141 400.0 COG0398@1|root,COG0398@2|Bacteria,1V3J1@1239|Firmicutes,4HHXX@91061|Bacilli,1ZEPX@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein ytxB - - - - - - - - - - - SNARE_assoc HPHIIJEP_03248 224308.BSU28960 3.46e-205 567.0 28MGE@1|root,2ZATN@2|Bacteria,1UC5R@1239|Firmicutes,4HESX@91061|Bacilli,1ZRWW@1386|Bacillus 91061|Bacilli S YtxC-like family ytxC - - - - - - - - - - - YtxC HPHIIJEP_03250 224308.BSU28950 0.0 1271.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,1ZB5W@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD HPHIIJEP_03251 224308.BSU28940 1.98e-189 525.0 COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,1ZBN8@1386|Bacillus 91061|Bacilli S HAD-hyrolase-like ysaA - 3.1.3.5,3.8.1.2 ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287 RC00017,RC00697 ko00000,ko00001,ko01000 - - - HAD_2 HPHIIJEP_03252 224308.BSU28930 0.0 1115.0 COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,4H9Z1@91061|Bacilli,1ZBKQ@1386|Bacillus 91061|Bacilli T Histidine kinase lytS - 2.7.13.3 ko:K07704 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - 5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase HPHIIJEP_03253 224308.BSU28920 1.13e-165 464.0 COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,1ZC3U@1386|Bacillus 91061|Bacilli T COG3279 Response regulator of the LytR AlgR family lytT GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg HPHIIJEP_03254 224308.BSU28910 8.47e-85 251.0 COG1380@1|root,COG1380@2|Bacteria,1V9Z2@1239|Firmicutes,4IR9S@91061|Bacilli,1ZHA7@1386|Bacillus 91061|Bacilli S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses lrgA GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - ko:K05338 ko02020,map02020 - - - ko00000,ko00001,ko02000 1.E.14.1 - - LrgA HPHIIJEP_03255 224308.BSU28900 5.34e-150 423.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4IQTD@91061|Bacilli,1ZRNK@1386|Bacillus 91061|Bacilli M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses lrgB - - ko:K05339 ko02020,map02020 - - - ko00000,ko00001 - - - LrgB HPHIIJEP_03257 224308.BSU28870 1.81e-111 321.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,1ZCBZ@1386|Bacillus 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N HPHIIJEP_03258 224308.BSU28860 3.93e-37 125.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,1ZJBX@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p HPHIIJEP_03259 1051501.AYTL01000030_gene2964 3.26e-76 228.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,1ZG75@1386|Bacillus 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 HPHIIJEP_03260 224308.BSU28840 1.27e-59 183.0 COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,4HNXQ@91061|Bacilli,1ZIYS@1386|Bacillus 91061|Bacilli S Membrane ysdA - - - - - - - - - - - DUF1294 HPHIIJEP_03261 224308.BSU28830 1.96e-89 262.0 29RHG@1|root,30CKE@2|Bacteria,1V4BT@1239|Firmicutes,4HIQA@91061|Bacilli,1ZH08@1386|Bacillus 91061|Bacilli S Sigma-w pathway protein YsdB ysdB - - - - - - - - - - - - HPHIIJEP_03262 224308.BSU28820 4.35e-262 717.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,1ZD06@1386|Bacillus 91061|Bacilli G COG1363 Cellulase M and related proteins ysdC - - - - - - - - - - - Peptidase_M42 HPHIIJEP_03263 224308.BSU28810 1.16e-240 660.0 COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,4HBSN@91061|Bacilli,1ZDPS@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - Glyco_hydro_43 HPHIIJEP_03264 224308.BSU28800 0.0 1006.0 COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,4HAWS@91061|Bacilli,1ZD9A@1386|Bacillus 91061|Bacilli G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome HPHIIJEP_03265 224308.BSU28790 0.0 1111.0 COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,4HC3A@91061|Bacilli,1ZB10@1386|Bacillus 91061|Bacilli C Belongs to the ribulokinase family araB - 2.7.1.16 ko:K00853 ko00040,ko01100,map00040,map01100 - R01526,R02439 RC00002,RC00538 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N HPHIIJEP_03266 224308.BSU28780 1.7e-170 475.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,1ZDGI@1386|Bacillus 91061|Bacilli G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II HPHIIJEP_03267 224308.BSU28770 1e-185 517.0 COG0647@1|root,COG0647@2|Bacteria,1UZNG@1239|Firmicutes,4HCI1@91061|Bacilli,1ZE6I@1386|Bacillus 91061|Bacilli G Haloacid dehalogenase-like hydrolase araL - - ko:K02101 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like HPHIIJEP_03268 224308.BSU28760 2.15e-281 769.0 COG0371@1|root,COG0371@2|Bacteria,1VTSP@1239|Firmicutes,4HTK1@91061|Bacilli,1ZR9Q@1386|Bacillus 91061|Bacilli I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species araM - 1.1.1.261 ko:K00096 ko00564,map00564 - R05679,R05680 RC00029 ko00000,ko00001,ko01000 - - - Fe-ADH_2 HPHIIJEP_03269 224308.BSU28750 0.0 872.0 COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,4HAYY@91061|Bacilli,1ZBMD@1386|Bacillus 91061|Bacilli G carbohydrate transport araN - - ko:K17234 ko02010,map02010 M00602 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.34 - - SBP_bac_1,SBP_bac_8 HPHIIJEP_03270 224308.BSU28740 1.94e-218 603.0 COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,4HDJS@91061|Bacilli,1ZDJF@1386|Bacillus 91061|Bacilli G carbohydrate transport araP - - ko:K17235 ko02010,map02010 M00602 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.34 - - BPD_transp_1 HPHIIJEP_03271 224308.BSU28730 6.34e-192 533.0 COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,4HCVZ@91061|Bacilli,1ZETQ@1386|Bacillus 91061|Bacilli G transport system permease araQ - - ko:K17236 ko02010,map02010 M00602 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.34 - - BPD_transp_1 HPHIIJEP_03272 224308.BSU28720 0.0 1027.0 COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,4HAZ7@91061|Bacilli,1ZE6H@1386|Bacillus 91061|Bacilli G alpha-L-arabinofuranosidase activity abfA - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C HPHIIJEP_03273 224308.BSU28710 0.0 1163.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,1ZC6K@1386|Bacillus 91061|Bacilli T Carbon starvation protein cstA GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0008150,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM HPHIIJEP_03274 1051501.AYTL01000030_gene2946 2.94e-69 212.0 COG0346@1|root,COG0346@2|Bacteria,1V9E0@1239|Firmicutes,4HX0J@91061|Bacilli,1ZHMS@1386|Bacillus 91061|Bacilli E Glyoxalase-like domain - - 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase_2 HPHIIJEP_03275 224308.BSU28690 0.0 892.0 COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli,1ZATD@1386|Bacillus 91061|Bacilli C Glycolate oxidase glcF - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 HPHIIJEP_03276 224308.BSU28680 0.0 902.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,1ZCQN@1386|Bacillus 91061|Bacilli C Glycolate oxidase subunit glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - iYO844.BSU28680 FAD-oxidase_C,FAD_binding_4 HPHIIJEP_03277 224308.BSU28670 4.53e-263 721.0 COG3835@1|root,COG3835@2|Bacteria,1UYW2@1239|Firmicutes,4HD2Q@91061|Bacilli,1ZD1P@1386|Bacillus 91061|Bacilli KT regulator cdaR_1 - - ko:K02647 - - - - ko00000,ko03000 - - - Diacid_rec,GGDEF,HTH_30 HPHIIJEP_03278 224308.BSU28660 4.37e-43 140.0 2E3SP@1|root,32YQ7@2|Bacteria,1VFJP@1239|Firmicutes,4HNJI@91061|Bacilli,1ZIXT@1386|Bacillus 91061|Bacilli S Belongs to the SspI family sspI - - ko:K06426 - - - - ko00000 - - - SSPI HPHIIJEP_03279 224308.BSU28650 1.81e-170 476.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,1ZBTY@1386|Bacillus 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind HPHIIJEP_03280 224308.BSU28640 1.81e-250 687.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,1ZANR@1386|Bacillus 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d HPHIIJEP_03281 224308.BSU28630 0.0 1542.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1ZB8G@1386|Bacillus 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind HPHIIJEP_03282 224308.BSU28620 8.48e-215 594.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli,1ZBHW@1386|Bacillus 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII HPHIIJEP_03283 224308.BSU28610 1.04e-54 171.0 COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,1ZHZX@1386|Bacillus 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division zapA - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA HPHIIJEP_03284 224308.BSU28600 1.09e-111 322.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,1ZDGZ@1386|Bacillus 91061|Bacilli S membrane protein, required for colicin V production yshB - - - - - - - - - - - Colicin_V HPHIIJEP_03285 224308.BSU28590 0.0 1111.0 COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,4HAI2@91061|Bacilli,1ZB3A@1386|Bacillus 91061|Bacilli L COG1796 DNA polymerase IV (family X) polX - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP HPHIIJEP_03286 224308.BSU28580 0.0 1456.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1ZBJV@1386|Bacillus 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr HPHIIJEP_03287 224308.BSU28570 3.76e-89 261.0 COG3766@1|root,COG3766@2|Bacteria,1V6MT@1239|Firmicutes,4HH4E@91061|Bacilli,1ZG9Y@1386|Bacillus 91061|Bacilli S membrane yshE - - ko:K08989 - - - - ko00000 - - - DUF350 HPHIIJEP_03288 224308.BSU28560 0.0 1127.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1ZAY1@1386|Bacillus 91061|Bacilli IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II lcfA - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C HPHIIJEP_03289 224308.BSU28550 5.74e-129 367.0 COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,4H9RC@91061|Bacilli,1ZAU5@1386|Bacillus 91061|Bacilli K Transcriptional regulator fadR GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K13770 - - - - ko00000,ko03000 - - - TetR_C_4,TetR_N HPHIIJEP_03290 224308.BSU28540 2.56e-175 489.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,1ZCKH@1386|Bacillus 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family fadB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 M00087 R03026,R04170,R04738,R04740,R04744,R04746 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 HPHIIJEP_03291 224308.BSU28530 2.58e-179 499.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,1ZBTA@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K03521 - - - - ko00000 - - - ETF HPHIIJEP_03292 224308.BSU28520 5e-227 626.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,1ZBCR@1386|Bacillus 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha HPHIIJEP_03293 224308.BSU28510 0.0 1043.0 COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,4HCUX@91061|Bacilli,1ZCNR@1386|Bacillus 91061|Bacilli G Alpha-L-arabinofuranosidase C-terminus xsa - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C HPHIIJEP_03294 1051501.AYTL01000030_gene2925 1.12e-69 210.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin HPHIIJEP_03295 224308.BSU28490 0.0 1159.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1ZBY1@1386|Bacillus 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N HPHIIJEP_03296 224308.BSU28470 1.38e-275 756.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,1ZDA6@1386|Bacillus 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 HPHIIJEP_03297 224308.BSU28460 8.53e-104 300.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,1ZQN2@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 HPHIIJEP_03298 224308.BSU28450 1.35e-140 397.0 COG2009@1|root,COG2009@2|Bacteria,1TQUI@1239|Firmicutes,4HBX0@91061|Bacilli,1ZBB5@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhC - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - iYO844.BSU28450 Sdh_cyt HPHIIJEP_03299 224308.BSU28440 0.0 1194.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,1ZBRD@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhA GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS05640 FAD_binding_2,Succ_DH_flav_C HPHIIJEP_03300 224308.BSU28430 2.33e-189 525.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,1ZAPQ@1386|Bacillus 91061|Bacilli C succinate dehydrogenase sdhB GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 HPHIIJEP_03301 224308.BSU28420 2.65e-102 296.0 COG0824@1|root,COG0824@2|Bacteria,1V6GS@1239|Firmicutes,4HJ05@91061|Bacilli,1ZH3F@1386|Bacillus 91061|Bacilli S thioesterase ysmA - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 HPHIIJEP_03302 1178537.BA1_03890 1.81e-41 136.0 COG2197@1|root,COG2197@2|Bacteria,1VBZR@1239|Firmicutes,4HKT4@91061|Bacilli,1ZHTA@1386|Bacillus 91061|Bacilli K Transcriptional regulator gerE - - ko:K01994 - - - - ko00000,ko03000 - - - GerE HPHIIJEP_03303 224308.BSU28400 1.6e-98 286.0 COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HKGN@91061|Bacilli,1ZQ3V@1386|Bacillus 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ysmB - - - - - - - - - - - MarR HPHIIJEP_03304 224308.BSU28390 4.49e-194 538.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,1ZBC9@1386|Bacillus 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race HPHIIJEP_03305 224308.BSU28380 1.62e-255 701.0 COG5401@1|root,COG5401@2|Bacteria,1TPQD@1239|Firmicutes,4HB1S@91061|Bacilli,1ZBZJ@1386|Bacillus 91061|Bacilli S COG5401 Spore germination protein gerM - - ko:K06298 - - - - ko00000 - - - Germane HPHIIJEP_03306 224308.BSU28370 2.04e-170 476.0 COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,4HBH3@91061|Bacilli,1ZBXN@1386|Bacillus 91061|Bacilli J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - Ham1p_like,RNase_PH,RNase_PH_C HPHIIJEP_03307 1051501.AYTL01000030_gene2912 7.86e-132 374.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli,1ZFJM@1386|Bacillus 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like HPHIIJEP_03308 224308.BSU28350 4.05e-119 340.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,1ZH0K@1386|Bacillus 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 HPHIIJEP_03310 224308.BSU28340 3.36e-181 506.0 COG3861@1|root,COG3861@2|Bacteria,1V9A1@1239|Firmicutes,4HISC@91061|Bacilli,1ZE4F@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ysnF - - - - - - - - - - - DUF2382,YflT HPHIIJEP_03311 1051501.AYTL01000030_gene2908 1.11e-203 571.0 COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Big_2,DUF11,Kelch_1 HPHIIJEP_03312 224308.BSU28330 2.83e-99 288.0 COG0454@1|root,COG0454@2|Bacteria,1V4EA@1239|Firmicutes,4HHBF@91061|Bacilli,1ZGG7@1386|Bacillus 91061|Bacilli K acetyltransferase ysnE GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - ko:K03829 - - - - ko00000,ko01000 - - - Acetyltransf_1 HPHIIJEP_03314 224308.BSU28310 0.0 1134.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,1ZB1D@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N HPHIIJEP_03315 224308.BSU28300 5.05e-110 317.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli,1ZFP3@1386|Bacillus 91061|Bacilli E Acetolactate synthase ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ACT,ACT_5,ALS_ss_C HPHIIJEP_03316 224308.BSU28290 9.59e-245 672.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli,1ZCH5@1386|Bacillus 91061|Bacilli EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN HPHIIJEP_03317 224308.BSU28280 0.0 999.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli,1ZC5T@1386|Bacillus 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer HPHIIJEP_03318 224308.BSU28270 3.53e-254 698.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli,1ZB3Y@1386|Bacillus 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh HPHIIJEP_03319 224308.BSU28260 0.0 951.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,1ZCF1@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase HPHIIJEP_03320 224308.BSU28250 4.4e-149 418.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HH3U@91061|Bacilli,1ZQWB@1386|Bacillus 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C HPHIIJEP_03321 224308.BSU28240 1.11e-239 659.0 COG0457@1|root,COG1477@1|root,COG0457@2|Bacteria,COG1477@2|Bacteria,1V7T7@1239|Firmicutes,4HKAH@91061|Bacilli,1ZS6N@1386|Bacillus 91061|Bacilli H Tetratricopeptide repeat ysoA - - - - - - - - - - - TPR_19 HPHIIJEP_03322 224308.BSU28230 2.54e-286 784.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1ZBRE@1386|Bacillus 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N HPHIIJEP_03323 224308.BSU28220 1.15e-296 810.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX HPHIIJEP_03324 224308.BSU28210 0.0 1075.0 COG0470@1|root,COG1067@1|root,COG0470@2|Bacteria,COG1067@2|Bacteria,1TP2K@1239|Firmicutes,4HB6F@91061|Bacilli,1ZBW1@1386|Bacillus 91061|Bacilli LO Belongs to the peptidase S16 family lonB - 3.4.21.53 ko:K04076 - - - - ko00000,ko01000,ko01002 - - - AAA,Lon_C HPHIIJEP_03325 224308.BSU28200 0.0 1486.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1ZAXX@1386|Bacillus 91061|Bacilli O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C HPHIIJEP_03326 224308.BSU28190 7.6e-139 392.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,1ZBX7@1386|Bacillus 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 HPHIIJEP_03327 224308.BSU28180 4.77e-116 332.0 2CYGZ@1|root,32T47@2|Bacteria,1VA1R@1239|Firmicutes,4HM46@91061|Bacilli,1ZGJG@1386|Bacillus 91061|Bacilli - - ysxD - - - - - - - - - - - - HPHIIJEP_03328 224308.BSU28170 6.39e-316 862.0 COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,4HAVC@91061|Bacilli,1ZBER@1386|Bacillus 91061|Bacilli H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08420 GlutR_N,GlutR_dimer,Shikimate_DH HPHIIJEP_03329 224308.BSU28160 6.56e-187 520.0 COG0755@1|root,COG0755@2|Bacteria,1U8IP@1239|Firmicutes,4HD6H@91061|Bacilli,1ZBFP@1386|Bacillus 91061|Bacilli O cytochrome C hemX GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - ko:K02497 - - - - ko00000 - - - Cytochrom_C_asm HPHIIJEP_03330 224308.BSU28150 8.91e-220 607.0 COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,1ZCR0@1386|Bacillus 91061|Bacilli H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC HPHIIJEP_03331 224308.BSU28140 1.01e-183 511.0 COG1587@1|root,COG1587@2|Bacteria,1UHSJ@1239|Firmicutes,4HFY4@91061|Bacilli,1ZGER@1386|Bacillus 91061|Bacilli H Uroporphyrinogen-III synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 HPHIIJEP_03332 224308.BSU28130 3.7e-233 641.0 COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,1ZARK@1386|Bacillus 91061|Bacilli H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD HPHIIJEP_03333 224308.BSU28120 3.53e-312 850.0 COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,1ZBUT@1386|Bacillus 91061|Bacilli H Glutamate-1-semialdehyde aminotransferase hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - iSB619.SA_RS08395 Aminotran_3 HPHIIJEP_03334 224308.BSU28110 0.0 952.0 COG1388@1|root,COG1388@2|Bacteria,1U052@1239|Firmicutes,4HF2C@91061|Bacilli,1ZB2H@1386|Bacillus 91061|Bacilli M stage VI sporulation protein D spoVID GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06417 - - - - ko00000 - - - LysM HPHIIJEP_03335 224308.BSU28100 4.82e-252 691.0 COG2334@1|root,COG2334@2|Bacteria,1V54J@1239|Firmicutes,4HH2K@91061|Bacilli,1ZB97@1386|Bacillus 91061|Bacilli S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response ysxE - - - - - - - - - - - APH HPHIIJEP_03336 224308.BSU28099 1.53e-35 120.0 2ESUV@1|root,33KD9@2|Bacteria,1VP5F@1239|Firmicutes,4HSYB@91061|Bacilli,1ZIWU@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03337 224308.BSU28090 0.0 1793.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,1ZAS4@1386|Bacillus 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 HPHIIJEP_03338 224308.BSU28080 7.42e-314 854.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,1ZAWN@1386|Bacillus 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M HPHIIJEP_03339 224308.BSU28070 3.75e-163 458.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli,1ZCQ2@1386|Bacillus 91061|Bacilli NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases comC - 3.4.23.43 ko:K02236,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 HPHIIJEP_03340 224308.BSU28060 1.74e-210 585.0 29RG0@1|root,30CIU@2|Bacteria,1U9YU@1239|Firmicutes,4IK6R@91061|Bacilli,1ZFFM@1386|Bacillus 91061|Bacilli S Sporulation related domain spoIIB - - ko:K06380 - - - - ko00000 - - - SPOR HPHIIJEP_03341 224308.BSU28050 1.73e-132 375.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,1ZGDP@1386|Bacillus 91061|Bacilli D septum formation protein Maf maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf HPHIIJEP_03342 224308.BSU28040 1.39e-161 452.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,1ZBYH@1386|Bacillus 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC HPHIIJEP_03343 224308.BSU28030 5.26e-235 647.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,1ZB43@1386|Bacillus 91061|Bacilli D Rod shape-determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl HPHIIJEP_03344 224308.BSU28020 7.78e-202 559.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,1ZC8X@1386|Bacillus 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC HPHIIJEP_03345 224308.BSU28010 8.72e-111 319.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNWW@91061|Bacilli,1ZGID@1386|Bacillus 91061|Bacilli M shape-determining protein mreD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD HPHIIJEP_03346 224308.BSU28000 4.3e-158 443.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,1ZDSJ@1386|Bacillus 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C HPHIIJEP_03347 224308.BSU27990 1.13e-183 511.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,1ZB5P@1386|Bacillus 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA HPHIIJEP_03348 224308.BSU27980 3.03e-186 518.0 COG0739@1|root,COG0739@2|Bacteria,1TSQI@1239|Firmicutes,4HFC8@91061|Bacilli,1ZFJN@1386|Bacillus 91061|Bacilli M COG0739 Membrane proteins related to metalloendopeptidases spoIVFA - - ko:K06401 - - - - ko00000 - - - Peptidase_M23 HPHIIJEP_03349 224308.BSU27970 3.74e-208 575.0 COG1994@1|root,COG1994@2|Bacteria,1V72P@1239|Firmicutes,4IR6Y@91061|Bacilli,1ZAQ2@1386|Bacillus 91061|Bacilli S Stage IV sporulation protein spoIVFB - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M50,Peptidase_M50B HPHIIJEP_03350 224308.BSU27960 6.34e-66 200.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,1ZGZG@1386|Bacillus 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p HPHIIJEP_03351 224308.BSU27950 6.28e-73 219.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,1ZI1F@1386|Bacillus 91061|Bacilli J ribosomal protein ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp HPHIIJEP_03352 1051501.AYTL01000030_gene2867 2.7e-61 188.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,1ZGZ9@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 HPHIIJEP_03353 224308.BSU27930 4.25e-139 392.0 COG3290@1|root,COG3290@2|Bacteria,1V8IS@1239|Firmicutes,4HQ4T@91061|Bacilli,1ZHUN@1386|Bacillus 91061|Bacilli T Sporulation initiation phospho-transferase B, C-terminal spo0B GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K06375 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko01000 - - - SPOB_a,SPOB_ab HPHIIJEP_03354 224308.BSU27920 5.59e-308 839.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,1ZCM4@1386|Bacillus 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 HPHIIJEP_03355 224308.BSU27910 4.75e-96 280.0 COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,1ZFNK@1386|Bacillus 91061|Bacilli S Belongs to the UPF0735 family pheB - 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27910 ACT,ACT_4 HPHIIJEP_03356 224308.BSU27900 1.43e-208 576.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli,1ZAVW@1386|Bacillus 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT HPHIIJEP_03357 224308.BSU27890 5.02e-123 351.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,1ZGFK@1386|Bacillus 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 HPHIIJEP_03358 224308.BSU27880 8.24e-291 793.0 COG1104@1|root,COG1104@2|Bacteria,1TPYU@1239|Firmicutes,4HA5J@91061|Bacilli,1ZCRY@1386|Bacillus 91061|Bacilli E Cysteine desulfurase nifS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 HPHIIJEP_03359 224308.BSU27870 0.0 1039.0 COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,4H9ZZ@91061|Bacilli,1ZBIE@1386|Bacillus 91061|Bacilli H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C HPHIIJEP_03360 224308.BSU27860 1.19e-200 556.0 COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,4HB46@91061|Bacilli,1ZBVN@1386|Bacillus 91061|Bacilli H Belongs to the NadC ModD family nadC GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N HPHIIJEP_03361 224308.BSU27850 2.66e-271 741.0 COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,4H9QG@91061|Bacilli,1ZAR3@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA HPHIIJEP_03362 224308.BSU27840 2.43e-217 607.0 COG1388@1|root,COG1388@2|Bacteria,1VETU@1239|Firmicutes,4HP2D@91061|Bacilli,1ZD0H@1386|Bacillus 91061|Bacilli M spore coat assembly protein SafA safA GO:0003674,GO:0005488,GO:0005515,GO:0019899,GO:0051117 - ko:K06370 - - - - ko00000 - - - LysM HPHIIJEP_03363 720555.BATR1942_11680 8.94e-71 220.0 2C7CE@1|root,30872@2|Bacteria,1V67M@1239|Firmicutes,4HHGE@91061|Bacilli,1ZDZH@1386|Bacillus 91061|Bacilli S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) - - - ko:K06345 - - - - ko00000 - - - Spore_YhcN_YlaJ HPHIIJEP_03364 224308.BSU27820 3.51e-164 460.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,1ZBN0@1386|Bacillus 91061|Bacilli K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg HPHIIJEP_03365 224308.BSU27810 0.0 911.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli,1ZAX7@1386|Bacillus 91061|Bacilli E Sodium alanine symporter yrbD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp HPHIIJEP_03367 1051501.AYTL01000030_gene2853 1.28e-67 206.0 2CJYE@1|root,32SB3@2|Bacteria,1VAGT@1239|Firmicutes,4HRVP@91061|Bacilli,1ZH9N@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5412) - - - - - - - - - - - - DUF5412 HPHIIJEP_03369 224308.BSU27785 1.91e-151 426.0 COG2112@1|root,COG2112@2|Bacteria,1UIYE@1239|Firmicutes,4ISX4@91061|Bacilli,1ZF0H@1386|Bacillus 91061|Bacilli T serine threonine protein kinase yrzF - - - - - - - - - - - Pkinase HPHIIJEP_03370 224308.BSU27770 4.59e-247 678.0 COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HAKY@91061|Bacilli,1ZBDM@1386|Bacillus 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold idhA - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C HPHIIJEP_03371 224308.BSU27760 0.0 879.0 COG0477@1|root,COG2814@2|Bacteria,1TRNB@1239|Firmicutes,4HCAI@91061|Bacilli,1ZCJH@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily csbX - - - - - - - - - - - MFS_1 HPHIIJEP_03372 224308.BSU27750 6.46e-121 345.0 2DGQY@1|root,32U7R@2|Bacteria,1V83A@1239|Firmicutes,4HKRI@91061|Bacilli,1ZH9Y@1386|Bacillus 91061|Bacilli S BofC C-terminal domain bofC - - ko:K06318 - - - - ko00000 - - - BOFC_N,BofC_C HPHIIJEP_03373 224308.BSU27740 2.84e-137 389.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,1ZBJT@1386|Bacillus 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N HPHIIJEP_03374 224308.BSU27730 9.14e-239 656.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,1ZC5A@1386|Bacillus 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N HPHIIJEP_03375 1051501.AYTL01000030_gene2846 2.91e-30 107.0 2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4HPC6@91061|Bacilli,1ZJ6M@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2905) yrzS - - - - - - - - - - - DUF2905 HPHIIJEP_03376 224308.BSU27720 6.03e-248 680.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,1ZB71@1386|Bacillus 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth HPHIIJEP_03377 224308.BSU27710 4.74e-292 795.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,1ZBFJ@1386|Bacillus 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT HPHIIJEP_03378 224308.BSU27700 1.29e-52 166.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,1ZHST@1386|Bacillus 91061|Bacilli U Preprotein translocase subunit YajC yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC HPHIIJEP_03379 224308.BSU27690 1.46e-96 281.0 2E8Q1@1|root,33314@2|Bacteria,1VFPE@1239|Firmicutes,4HPJ2@91061|Bacilli,1ZHSS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3792) yrzE - - - - - - - - - - - DUF3792 HPHIIJEP_03380 224308.BSU27680 4.1e-143 405.0 COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,4HHEY@91061|Bacilli,1ZDIR@1386|Bacillus 91061|Bacilli S membrane yrbG - - - - - - - - - - - DUF421 HPHIIJEP_03381 224308.BSU27670 0.0 924.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HAB7@91061|Bacilli,1ZDHC@1386|Bacillus 91061|Bacilli S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid spoVB - - ko:K06409 - - - - ko00000,ko02000 2.A.66.2.14 - - Polysacc_synt,Polysacc_synt_C HPHIIJEP_03382 224308.BSU27660 5.53e-65 197.0 2E6NG@1|root,3318Y@2|Bacteria,1VHES@1239|Firmicutes,4HP4D@91061|Bacilli,1ZJ02@1386|Bacillus 91061|Bacilli S Post-transcriptional regulator yrzD - - - - - - - - - - - Post_transc_reg HPHIIJEP_03383 224308.BSU27650 0.0 1352.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,4HB6K@91061|Bacilli,1ZBS9@1386|Bacillus 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG HPHIIJEP_03384 224308.BSU27640 6.51e-114 327.0 COG0490@1|root,COG0490@2|Bacteria,1V544@1239|Firmicutes,4HI3A@91061|Bacilli,1ZGIQ@1386|Bacillus 91061|Bacilli P regulatory, ligand-binding protein related to C-terminal domains of K channels trkA1 - - ko:K07228 - - - - ko00000 - - - TrkA_C HPHIIJEP_03385 224308.BSU27630 1.07e-64 197.0 COG5416@1|root,COG5416@2|Bacteria,1VGMG@1239|Firmicutes,4HQ29@91061|Bacilli,1ZIY0@1386|Bacillus 91061|Bacilli S Lipopolysaccharide assembly protein A domain yrvD - - - - - - - - - - - LapA_dom HPHIIJEP_03386 224308.BSU27620 0.0 1533.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C HPHIIJEP_03387 224308.BSU27610 2.53e-118 338.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,1ZD01@1386|Bacillus 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran HPHIIJEP_03388 224308.BSU27600 0.0 1429.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,1ZBN6@1386|Bacillus 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS HPHIIJEP_03389 1051501.AYTL01000030_gene2832 1.36e-90 266.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase HPHIIJEP_03390 224308.BSU27580 0.0 941.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,1ZDI1@1386|Bacillus 91061|Bacilli M COG3103 SH3 domain protein lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 HPHIIJEP_03392 224308.BSU27560 3e-310 845.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,1ZBXR@1386|Bacillus 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His HPHIIJEP_03393 224308.BSU27550 0.0 1150.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,1ZBXI@1386|Bacillus 91061|Bacilli J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon HPHIIJEP_03394 224308.BSU27540 2.29e-176 492.0 COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,4H9KZ@91061|Bacilli,1ZBGG@1386|Bacillus 91061|Bacilli H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 yrvM GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K22132 - - - - ko00000,ko03016 - - - ThiF HPHIIJEP_03395 224308.BSU27530 6.69e-301 821.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,1ZBCW@1386|Bacillus 91061|Bacilli L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N HPHIIJEP_03396 224308.BSU27520 8.12e-93 271.0 COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,4HHCF@91061|Bacilli,1ZFKT@1386|Bacillus 91061|Bacilli K Transcriptional regulator cymR GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0032991,GO:0032993,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044212,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0071840,GO:0097159,GO:1901363 - ko:K17472 - - - - ko00000,ko03000 - - - Rrf2 HPHIIJEP_03397 224308.BSU27510 6.02e-269 736.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,1ZB1B@1386|Bacillus 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 HPHIIJEP_03398 224308.BSU27500 5.64e-279 761.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,1ZBWQ@1386|Bacillus 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans HPHIIJEP_03399 1051501.AYTL01000030_gene2822 1.01e-20 93.6 COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat yrrB - - - - - - - - - - - TPR_1,TPR_16,TPR_2,TPR_6,TPR_8 HPHIIJEP_03400 224308.BSU27480 0.0 1568.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,1ZAYS@1386|Bacillus 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 HPHIIJEP_03401 224308.BSU27470 1.44e-107 310.0 COG3881@1|root,COG3881@2|Bacteria,1VEG9@1239|Firmicutes,4HPBU@91061|Bacilli,1ZH8E@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yrrD - - - - - - - - - - - PRC HPHIIJEP_03402 224308.BSU27469 8.4e-42 136.0 2E4YS@1|root,32ZSJ@2|Bacteria,1VEX3@1239|Firmicutes,4HNZ8@91061|Bacilli,1ZIT3@1386|Bacillus 91061|Bacilli - - yrzR - - - - - - - - - - - - HPHIIJEP_03403 279010.BL05285 5.38e-12 60.1 2BGYN@1|root,32AYR@2|Bacteria,1UB24@1239|Firmicutes,4IMF0@91061|Bacilli,1ZJZY@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3918) - - - - - - - - - - - - DUF3918 HPHIIJEP_03404 224308.BSU27460 9.26e-140 396.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,1ZCE8@1386|Bacillus 91061|Bacilli P ABC transporter glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 HPHIIJEP_03405 224308.BSU27450 3.24e-139 395.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,1ZCEF@1386|Bacillus 91061|Bacilli P ABC transporter glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 HPHIIJEP_03406 224308.BSU27440 1.01e-184 514.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,1ZCGF@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family glnH - - ko:K09969,ko:K10039 ko02010,map02010 M00228,M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 HPHIIJEP_03407 224308.BSU27430 2.21e-168 471.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component glnQ - - ko:K09972,ko:K10041 ko02010,map02010 M00228,M00232 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran HPHIIJEP_03408 224308.BSU27420 1.25e-241 665.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,1ZBGE@1386|Bacillus 91061|Bacilli S AI-2E family transporter yrrI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport HPHIIJEP_03409 224308.BSU27410 0.0 1726.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,1ZB9E@1386|Bacillus 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD HPHIIJEP_03410 224308.BSU27400 2.22e-55 172.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 HPHIIJEP_03411 224308.BSU27390 5.49e-93 271.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,1ZG6Y@1386|Bacillus 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX HPHIIJEP_03412 224308.BSU27380 2.94e-60 185.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,1ZI20@1386|Bacillus 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 HPHIIJEP_03413 224308.BSU27370 7.51e-242 666.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,1ZC44@1386|Bacillus 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG HPHIIJEP_03414 224308.BSU27360 1.98e-154 433.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli,1ZFK8@1386|Bacillus 91061|Bacilli S O-methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 HPHIIJEP_03415 224308.BSU27350 6.3e-222 612.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli,1ZAXB@1386|Bacillus 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 HPHIIJEP_03416 224308.BSU27340 5.4e-312 849.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli,1ZC7K@1386|Bacillus 91061|Bacilli O COG0826 Collagenase and related proteases yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C HPHIIJEP_03417 224308.BSU27330 1.29e-147 416.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,1ZB2B@1386|Bacillus 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK HPHIIJEP_03418 224308.BSU27320 1.14e-101 295.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N HPHIIJEP_03419 224308.BSU27310 0.0 1135.0 COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,4HC5S@91061|Bacilli,1ZBDB@1386|Bacillus 91061|Bacilli M Penicillin-binding Protein pbpI - - ko:K21468 - - - - ko00000,ko01011 - - - PBP_dimer,Transpeptidase HPHIIJEP_03420 224308.BSU27300 1.42e-102 303.0 2BJ57@1|root,32DEE@2|Bacteria,1V93H@1239|Firmicutes,4HN71@91061|Bacilli,1ZH00@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1510) yrrS - - - - - - - - - - - DUF1510 HPHIIJEP_03421 224308.BSU27290 4.94e-36 122.0 2E6WR@1|root,331G7@2|Bacteria,1VHCS@1239|Firmicutes,4HQVN@91061|Bacilli,1ZIT5@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2536) yrzA - - - - - - - - - - - DUF2536 HPHIIJEP_03422 224308.BSU27280 9.86e-153 429.0 COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,4HHF1@91061|Bacilli,1ZFN7@1386|Bacillus 91061|Bacilli Q Could be a S-adenosyl-L-methionine-dependent methyltransferase yrrT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00609 R10404 RC00003 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 HPHIIJEP_03423 224308.BSU27270 8.02e-161 451.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,1ZB7T@1386|Bacillus 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 HPHIIJEP_03424 224308.BSU27260 4.07e-217 599.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,1ZD93@1386|Bacillus 91061|Bacilli E Cysteine synthase mccA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042127,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0065007,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.134,2.5.1.47 ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00609 R00897,R03601,R04859,R10305 RC00020,RC00069,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02385 PALP HPHIIJEP_03425 224308.BSU27250 2.86e-267 732.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,1ZAR9@1386|Bacillus 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP HPHIIJEP_03426 224308.BSU27240 6.93e-49 155.0 2E8M6@1|root,332YN@2|Bacteria,1VFSW@1239|Firmicutes,4HNHX@91061|Bacilli,1ZIGK@1386|Bacillus 91061|Bacilli S YrhC-like protein yrhC - - - - - - - - - - - YrhC HPHIIJEP_03427 224308.BSU27230 1.73e-102 297.0 COG2427@1|root,COG2427@2|Bacteria,1V6Z7@1239|Firmicutes,4HIG1@91061|Bacilli,1ZHM2@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1641) yrhD - - - - - - - - - - - DUF1641 HPHIIJEP_03428 224308.BSU27220 0.0 1978.0 COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,4IS5E@91061|Bacilli,1ZS18@1386|Bacillus 91061|Bacilli C formate dehydrogenase (NAD+) activity yjgC GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 HPHIIJEP_03429 224308.BSU27210 4.41e-80 238.0 COG5609@1|root,COG5609@2|Bacteria,1V8MU@1239|Firmicutes,4HIS7@91061|Bacilli,1ZHGK@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (DUF2294) yrhF - - - - - - - - - - - DUF2294 HPHIIJEP_03430 224308.BSU27200 1.38e-183 511.0 COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,4HB22@91061|Bacilli,1ZC1K@1386|Bacillus 91061|Bacilli P Formate nitrite yrhG GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K21993 - - - - ko00000,ko02000 1.A.16.2 - - Form_Nir_trans HPHIIJEP_03432 1178537.BA1_10431 9.39e-08 49.7 29T4S@1|root,30EBG@2|Bacteria,1UCCN@1239|Firmicutes,4INV1@91061|Bacilli,1ZNZI@1386|Bacillus 91061|Bacilli S Probable sporulation protein (Bac_small_yrzI) - - - - - - - - - - - - Bac_small_YrzI HPHIIJEP_03433 224308.BSU27180 3.68e-125 356.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase yrhH - - - - - - - - - - - Methyltransf_11,Methyltransf_25 HPHIIJEP_03434 224308.BSU27170 2.26e-135 383.0 COG1309@1|root,COG1309@2|Bacteria,1VHP8@1239|Firmicutes,4IPYC@91061|Bacilli,1ZREU@1386|Bacillus 91061|Bacilli K Tetracycline repressor, C-terminal all-alpha domain - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - ko:K22106 - - - - ko00000,ko03000 - - - TetR_C_10,TetR_N HPHIIJEP_03435 224308.BSU27160 0.0 2079.0 COG0369@1|root,COG2124@1|root,COG0369@2|Bacteria,COG2124@2|Bacteria,1TS1E@1239|Firmicutes,4HCWS@91061|Bacilli,1ZQAP@1386|Bacillus 91061|Bacilli C Belongs to the cytochrome P450 family yrhJ GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0004497,GO:0005488,GO:0005504,GO:0005506,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0016705,GO:0016712,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031406,GO:0032553,GO:0032787,GO:0033293,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.14.14.1,1.6.2.4 ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 - R03629,R04121,R05259 RC00046,RC01311 ko00000,ko00001,ko00199,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1,p450 HPHIIJEP_03436 224308.BSU27150 6.32e-59 182.0 2E53A@1|root,32ZWE@2|Bacteria,1UPW8@1239|Firmicutes,4HNZR@91061|Bacilli,1ZSKD@1386|Bacillus 91061|Bacilli S YrhK-like protein yrhK - - - - - - - - - - - YrhK HPHIIJEP_03437 224308.BSU27140 0.0 1229.0 COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,1ZB6R@1386|Bacillus 91061|Bacilli I Acyltransferase family oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 HPHIIJEP_03438 224308.BSU27130 2.03e-190 530.0 2DBFK@1|root,2Z8Z7@2|Bacteria,1TQKG@1239|Firmicutes,4HDJX@91061|Bacilli,1ZDFG@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3298) rsiV - - - - - - - - - - - DUF3298,DUF4163,DUF4179 HPHIIJEP_03439 224308.BSU27120 9.97e-114 326.0 COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,4HJX8@91061|Bacilli,1ZGIA@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigV - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_03440 224308.BSU27110 2.05e-94 281.0 COG1378@1|root,COG1378@2|Bacteria,1TSY3@1239|Firmicutes,4HPSV@91061|Bacilli,1ZR3N@1386|Bacillus 91061|Bacilli K Archaeal transcriptional regulator TrmB yrhO - - - - - - - - - - - Regulator_TrmB,TrmB HPHIIJEP_03441 224308.BSU27110 1.46e-85 258.0 COG1378@1|root,COG1378@2|Bacteria,1TSY3@1239|Firmicutes,4HPSV@91061|Bacilli,1ZR3N@1386|Bacillus 91061|Bacilli K Archaeal transcriptional regulator TrmB yrhO - - - - - - - - - - - Regulator_TrmB,TrmB HPHIIJEP_03442 224308.BSU27100 5.63e-137 389.0 COG1280@1|root,COG1280@2|Bacteria,1V22Q@1239|Firmicutes,4HGG7@91061|Bacilli,1ZFWG@1386|Bacillus 91061|Bacilli E LysE type translocator yrhP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - - - - - - - - - - LysE HPHIIJEP_03443 224308.BSU27090 0.0 874.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,1ZAQB@1386|Bacillus 91061|Bacilli E COG1113 Gamma-aminobutyrate permease and related permeases aapA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease HPHIIJEP_03444 224308.BSU27080 0.0 1793.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,1ZCV2@1386|Bacillus 91061|Bacilli K PTS system fructose IIA component levR - - - - - - - - - - - EIIA-man,PRD,Sigma54_activat HPHIIJEP_03445 224308.BSU27070 1.08e-96 281.0 COG2893@1|root,COG2893@2|Bacteria,1VB2D@1239|Firmicutes,4HMGK@91061|Bacilli,1ZN60@1386|Bacillus 91061|Bacilli G PTS system fructose IIA component levD - 2.7.1.191,2.7.1.202 ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00304 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.2 - - EIIA-man HPHIIJEP_03446 224308.BSU27060 6.27e-106 306.0 COG3444@1|root,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,1ZDQ9@1386|Bacillus 91061|Bacilli G PTS system mannose fructose sorbose family ptnA - 2.7.1.191,2.7.1.202 ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00304 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.2 - - EIIA-man,PTSIIB_sorb HPHIIJEP_03447 224308.BSU27050 6.11e-168 472.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,1ZE3U@1386|Bacillus 91061|Bacilli G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC levF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00304 R02630,R03232,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.2,4.A.6.1.4 - - EII-Sor HPHIIJEP_03448 224308.BSU27040 1.39e-192 535.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,1ZCPZ@1386|Bacillus 91061|Bacilli G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID levG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00304 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.2 - - EIID-AGA HPHIIJEP_03449 224308.BSU27030 0.0 1374.0 COG1621@1|root,COG1621@2|Bacteria,1TS4M@1239|Firmicutes,4HC82@91061|Bacilli,1ZPVF@1386|Bacillus 91061|Bacilli G Belongs to the glycosyl hydrolase 32 family sacC GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.80 ko:K03332 ko00051,map00051 - R00879 - ko00000,ko00001,ko01000 - - - Big_2,CW_binding_1,Cadherin-like,Glyco_hydro_32C,Glyco_hydro_32N HPHIIJEP_03450 224308.BSU27020 6.46e-116 332.0 COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,1ZFMH@1386|Bacillus 91061|Bacilli S protease yfkM - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI HPHIIJEP_03451 224308.BSU27010 5.62e-252 691.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,1ZB8Z@1386|Bacillus 91061|Bacilli C alcohol dehydrogenase adhA - - ko:K13979 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N HPHIIJEP_03452 224308.BSU27009 4.53e-33 114.0 COG0599@1|root,COG0599@2|Bacteria 2|Bacteria S peroxiredoxin activity yphJ - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD HPHIIJEP_03453 224308.BSU27000 3.17e-68 209.0 COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,4HKZ9@91061|Bacilli,1ZHPE@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance adhR - - ko:K21745 - - - - ko00000,ko03000 - - - MerR,MerR_1 HPHIIJEP_03454 224308.BSU26990 7.23e-66 200.0 COG5577@1|root,COG5577@2|Bacteria,1VB60@1239|Firmicutes,4HM7J@91061|Bacilli,1ZI7J@1386|Bacillus 91061|Bacilli M Spore coat protein yraD - - ko:K06439 - - - - ko00000 - - - Coat_F HPHIIJEP_03455 224308.BSU26980 2.05e-34 118.0 2EGYD@1|root,33AQH@2|Bacteria,1VK4Z@1239|Firmicutes,4HRB4@91061|Bacilli,1ZJAB@1386|Bacillus 91061|Bacilli - - yraE - - ko:K06440 - - - - ko00000 - - - - HPHIIJEP_03456 224308.BSU26970 3.41e-279 762.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,1ZB9D@1386|Bacillus 91061|Bacilli E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases adhB - 1.1.1.1,1.1.1.284,1.2.1.46 ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 - R00604,R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00188,RC00649,RC01715,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N HPHIIJEP_03457 224308.BSU26960 9.61e-84 247.0 COG5577@1|root,COG5577@2|Bacteria,1V4E3@1239|Firmicutes,4HH3T@91061|Bacilli,1ZH5H@1386|Bacillus 91061|Bacilli M Spore coat protein yraF - - - - - - - - - - - Coat_F HPHIIJEP_03458 224308.BSU26950 4.19e-50 159.0 2DA30@1|root,347MA@2|Bacteria,1W180@1239|Firmicutes,4HYA3@91061|Bacilli,1ZQW3@1386|Bacillus 91061|Bacilli - - yraG - - ko:K06440 - - - - ko00000 - - - - HPHIIJEP_03459 224308.BSU26940 6.62e-87 255.0 COG0346@1|root,COG0346@2|Bacteria,1V9KE@1239|Firmicutes,4HK92@91061|Bacilli,1ZK71@1386|Bacillus 91061|Bacilli E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase,Glyoxalase_2 HPHIIJEP_03460 224308.BSU26930 2.92e-81 241.0 COG3103@1|root,COG4991@2|Bacteria,1VRDW@1239|Firmicutes,4HTEI@91061|Bacilli,1ZPM0@1386|Bacillus 91061|Bacilli T sh3 domain protein - - - - - - - - - - - - Peptidase_M23 HPHIIJEP_03461 224308.BSU26920 6.61e-80 237.0 COG3103@1|root,COG4991@2|Bacteria,1VRDW@1239|Firmicutes,4HTEI@91061|Bacilli,1ZPM0@1386|Bacillus 91061|Bacilli T sh3 domain protein - - - - - - - - - - - - Peptidase_M23 HPHIIJEP_03462 224308.BSU26910 1.02e-192 535.0 COG0596@1|root,COG0596@2|Bacteria,1VHJX@1239|Firmicutes,4HQIV@91061|Bacilli,1ZD51@1386|Bacillus 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 HPHIIJEP_03463 224308.BSU26900 5.07e-56 174.0 COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,4HNM8@91061|Bacilli,1ZHZQ@1386|Bacillus 91061|Bacilli S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain yraL - - - - - - - - - - - Mor HPHIIJEP_03464 224308.BSU26890 2.2e-193 536.0 COG3409@1|root,COG3409@2|Bacteria,1VCJN@1239|Firmicutes,4HTZB@91061|Bacilli 91061|Bacilli M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan csn GO:0003674,GO:0003824,GO:0004553,GO:0016787,GO:0016798,GO:0016977 3.2.1.132 ko:K01233 ko00520,ko01100,map00520,map01100 - R02833 - ko00000,ko00001,ko01000 - - - Glyco_hydro_46 HPHIIJEP_03465 224308.BSU26880 1.15e-260 714.0 COG2828@1|root,COG2828@2|Bacteria,1TPP6@1239|Firmicutes,4HD7I@91061|Bacilli,1ZBED@1386|Bacillus 91061|Bacilli S PrpF protein yraM - - - - - - - - - - - PrpF HPHIIJEP_03466 224308.BSU26870 7e-209 577.0 COG0583@1|root,COG0583@2|Bacteria,1TZ6U@1239|Firmicutes,4HB3Y@91061|Bacilli,1ZB8N@1386|Bacillus 91061|Bacilli K Transcriptional regulator yraN - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_03467 224308.BSU26860 2.06e-283 778.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,1ZCEQ@1386|Bacillus 91061|Bacilli C Citrate transporter yraO GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K03300,ko:K11639 ko02020,map02020 - - - ko00000,ko00001 2.A.11,2.A.11.1.1 - - CitMHS HPHIIJEP_03468 224308.BSU26850 4.9e-239 656.0 COG0667@1|root,COG0667@2|Bacteria,1UY4A@1239|Firmicutes,4HBZD@91061|Bacilli,1ZQG9@1386|Bacillus 91061|Bacilli C Aldo/keto reductase family yrpG - - - - - - - - - - - Aldo_ket_red HPHIIJEP_03469 224308.BSU26840 5.05e-121 345.0 COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,4HW99@91061|Bacilli,1ZMXR@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 HPHIIJEP_03470 224308.BSU26830 4.22e-164 461.0 COG3443@1|root,COG3443@2|Bacteria,1UI6E@1239|Firmicutes,4ISFG@91061|Bacilli,1ZS5B@1386|Bacillus 91061|Bacilli S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment zinT - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - Strep_his_triad,ZinT HPHIIJEP_03473 224308.BSU26820 6.85e-162 454.0 2CQ69@1|root,32SKI@2|Bacteria,1VCJR@1239|Firmicutes,4HNF9@91061|Bacilli,1ZFBY@1386|Bacillus 91061|Bacilli S Domain of unknown function, YrpD yrpD - - - - - - - - - - - YrpD HPHIIJEP_03474 224308.BSU26810 8.38e-189 524.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HBW9@91061|Bacilli,1ZG4P@1386|Bacillus 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race HPHIIJEP_03475 224308.BSU26800 4.23e-246 676.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,1ZBXS@1386|Bacillus 91061|Bacilli S COG2070 Dioxygenases related to 2-nitropropane dioxygenase npd - 1.13.12.16 ko:K00459 ko00910,map00910 - R00025 RC02541,RC02759 ko00000,ko00001,ko01000 - - - NMO HPHIIJEP_03476 224308.BSU26790 1.48e-212 586.0 2DB8K@1|root,2Z7S1@2|Bacteria,1TRA1@1239|Firmicutes,4HBIE@91061|Bacilli,1ZE40@1386|Bacillus 91061|Bacilli G Streptomycin adenylyltransferase aadK - - ko:K05593 - - - - ko00000,ko01000,ko01504 - - - Adenyl_transf HPHIIJEP_03477 224308.BSU26780 2.01e-118 338.0 COG2318@1|root,COG2318@2|Bacteria,1TSEV@1239|Firmicutes,4HCNJ@91061|Bacilli,1ZQV0@1386|Bacillus 91061|Bacilli S DinB family yrdA - - - - - - - - - - - DinB HPHIIJEP_03478 1051501.AYTL01000030_gene2759 2.14e-53 167.0 28RDP@1|root,30E2H@2|Bacteria,1UC1N@1239|Firmicutes,4INHQ@91061|Bacilli,1ZNHM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03479 358681.BBR47_48790 2.06e-11 71.6 2ANY6@1|root,31DZ3@2|Bacteria,1V9WT@1239|Firmicutes,4HK7G@91061|Bacilli,26YZS@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DUF4280) M1-394 - - - - - - - - - - - DUF4280 HPHIIJEP_03480 224308.BSU26770 1.04e-71 217.0 2ED2V@1|root,336ZS@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2568) - - - - - - - - - - - - DUF2568 HPHIIJEP_03481 224308.BSU26760 2.11e-130 370.0 COG1335@1|root,COG1335@2|Bacteria,1V70H@1239|Firmicutes,4HJXC@91061|Bacilli,1ZG9B@1386|Bacillus 91061|Bacilli Q Isochorismatase family yrdC - - - - - - - - - - - Isochorismatase HPHIIJEP_03482 224308.BSU26740 3.11e-289 790.0 COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,1ZC1Y@1386|Bacillus 91061|Bacilli C Cytochrome P450 cypA GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005506,GO:0006066,GO:0006082,GO:0006629,GO:0006706,GO:0006707,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016042,GO:0016053,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0016713,GO:0017144,GO:0018130,GO:0019752,GO:0020037,GO:0032787,GO:0034641,GO:0036199,GO:0042364,GO:0042440,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046148,GO:0046164,GO:0046394,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.46,1.14.15.13 ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 M00573 R10123 - ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 - - - p450 HPHIIJEP_03483 224308.BSU26730 7.91e-55 171.0 COG2732@1|root,COG2732@2|Bacteria,1VFHP@1239|Firmicutes,4HS3R@91061|Bacilli,1ZJ2M@1386|Bacillus 91061|Bacilli K ribonuclease inhibitor yrdF - - ko:K03623 - - - - ko00000 - - - Barstar HPHIIJEP_03484 224308.BSU26720 4.82e-103 298.0 COG1522@1|root,COG1522@2|Bacteria,1V319@1239|Firmicutes,4HFNU@91061|Bacilli,1ZD2Z@1386|Bacillus 91061|Bacilli K helix_turn_helix ASNC type bkdR GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type HPHIIJEP_03485 224308.BSU26710 3.26e-176 491.0 COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,4IQZH@91061|Bacilli,1ZRPV@1386|Bacillus 91061|Bacilli E AzlC protein azlC - - - - - - - - - - - AzlC HPHIIJEP_03486 224308.BSU26700 1.97e-66 202.0 COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,4HJID@91061|Bacilli,1ZHEG@1386|Bacillus 91061|Bacilli E Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD HPHIIJEP_03487 224308.BSU26690 4.09e-291 798.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,1ZAST@1386|Bacillus 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans HPHIIJEP_03489 224308.BSU26650 2.64e-215 595.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,1ZB56@1386|Bacillus 91061|Bacilli P COG1230 Co Zn Cd efflux system component czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer HPHIIJEP_03490 224308.BSU26640 1.01e-252 692.0 COG2072@1|root,COG2072@2|Bacteria,1UG83@1239|Firmicutes,4HAFV@91061|Bacilli,1ZC6B@1386|Bacillus 91061|Bacilli P Oxidoreductase trkA - - ko:K07222 - - - - ko00000 - - - FMO-like,Pyr_redox_3 HPHIIJEP_03491 224308.BSU26630 1.4e-203 563.0 COG0583@1|root,COG0583@2|Bacteria,1UYHT@1239|Firmicutes,4HETP@91061|Bacilli,1ZQ2D@1386|Bacillus 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_03492 224308.BSU26620 4.03e-215 595.0 COG0697@1|root,COG0697@2|Bacteria,1UZGC@1239|Firmicutes,4HDET@91061|Bacilli,1ZD9P@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yrdR - - - - - - - - - - - EamA HPHIIJEP_03493 224308.BSU26619 7.04e-23 87.8 29TCA@1|root,30EJC@2|Bacteria,1UCMX@1239|Firmicutes,4IP42@91061|Bacilli,1ZPCH@1386|Bacillus 91061|Bacilli S YrzO-like protein - - - - - - - - - - - - YrzO HPHIIJEP_03494 224308.BSU26610 4.85e-296 810.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yrkA - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HPHIIJEP_03495 224308.BSU26600 2.16e-108 311.0 COG0454@1|root,COG0456@2|Bacteria,1VBFC@1239|Firmicutes,4HJG1@91061|Bacilli,1ZQF0@1386|Bacillus 91061|Bacilli K FR47-like protein bltD - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU26600 Acetyltransf_1 HPHIIJEP_03496 224308.BSU26590 2.54e-267 734.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily blt GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08153,ko:K19578 - M00717,M00765 - - ko00000,ko00002,ko02000 2.A.1.2.70,2.A.1.2.8 - iYO844.BSU26590 MFS_1,MFS_1_like,MFS_2,Sugar_tr HPHIIJEP_03497 224308.BSU26580 3.56e-194 538.0 COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,4HGJF@91061|Bacilli,1ZQ1U@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance bltR - - - - - - - - - - - GyrI-like,MerR_1 HPHIIJEP_03498 224308.BSU26560 1.23e-135 383.0 COG0662@1|root,COG0662@2|Bacteria,1V3H4@1239|Firmicutes,4HH1K@91061|Bacilli,1ZFFQ@1386|Bacillus 91061|Bacilli G Cupin domain yrkC - - - - - - - - - - - Cupin_2 HPHIIJEP_03499 796606.BMMGA3_13625 3.32e-28 105.0 2E45C@1|root,32Z1E@2|Bacteria,1VFKM@1239|Firmicutes,4HP7B@91061|Bacilli,1ZIUB@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03500 326423.RBAM_005420 4.38e-52 164.0 COG1937@1|root,COG1937@2|Bacteria,1VFB9@1239|Firmicutes,4HNVQ@91061|Bacilli,1ZHTP@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yrkD - - - - - - - - - - - Trns_repr_metal HPHIIJEP_03501 224308.BSU26540 1.32e-106 308.0 COG2210@1|root,COG2210@2|Bacteria,1V2R5@1239|Firmicutes,4HG2Y@91061|Bacilli,1ZC42@1386|Bacillus 91061|Bacilli O DsrE/DsrF/DrsH-like family yrkE - - - - - - - - - - - DrsE_2,Rhodanese,TusA HPHIIJEP_03502 224308.BSU26530 2.19e-124 355.0 COG0425@1|root,COG0607@1|root,COG0425@2|Bacteria,COG0607@2|Bacteria,1V1GU@1239|Firmicutes,4HFR8@91061|Bacilli,1ZAVN@1386|Bacillus 91061|Bacilli OP Belongs to the sulfur carrier protein TusA family yrkF - - - - - - - - - - - Rhodanese,TusA HPHIIJEP_03503 1211814.CAPG01000077_gene3643 0.000112 43.1 COG2210@1|root,COG2210@2|Bacteria,1V3UE@1239|Firmicutes,4HH93@91061|Bacilli,1ZQ9Q@1386|Bacillus 91061|Bacilli S DsrE/DsrF-like family perX - - - - - - - - - - - DrsE_2 HPHIIJEP_03504 224308.BSU26510 4.75e-269 736.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TPE2@1239|Firmicutes,4H9WH@91061|Bacilli,1ZCD8@1386|Bacillus 91061|Bacilli P Rhodanese Homology Domain yrkH - - - - - - - - - - - Lactamase_B,Rhodanese HPHIIJEP_03505 326423.RBAM_005470 6.46e-49 155.0 COG0425@1|root,COG0425@2|Bacteria,1VEEC@1239|Firmicutes,4HNQT@91061|Bacilli,1ZI1V@1386|Bacillus 91061|Bacilli O Belongs to the sulfur carrier protein TusA family yrkI GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - - - - - - - - - - TusA HPHIIJEP_03506 224308.BSU26490 7.97e-160 451.0 COG0730@1|root,COG0730@2|Bacteria,1TRIE@1239|Firmicutes,4HARW@91061|Bacilli,1ZC6G@1386|Bacillus 91061|Bacilli S membrane transporter protein yrkJ - - ko:K07090 - - - - ko00000 - - - TauE HPHIIJEP_03507 224308.BSU26480 3.13e-104 301.0 28P6Z@1|root,2ZC1H@2|Bacteria,1V318@1239|Firmicutes,4HFZ4@91061|Bacilli,1ZH6Z@1386|Bacillus 91061|Bacilli S Protein of unknown function with HXXEE motif - - - - - - - - - - - - HXXEE HPHIIJEP_03508 224308.BSU26470 3.31e-125 356.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,1ZRNF@1386|Bacillus 91061|Bacilli S Flavodoxin-like fold yrkL - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 HPHIIJEP_03509 224308.BSU26450 5.41e-134 379.0 COG0454@1|root,COG0454@2|Bacteria,1UHQ4@1239|Firmicutes,4HKZ0@91061|Bacilli,1ZGRK@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yrkN - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_03510 224308.BSU26440 2.93e-280 767.0 COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,4HCR3@91061|Bacilli,1ZBX3@1386|Bacillus 91061|Bacilli P Protein of unknown function (DUF418) yrkO - - ko:K07148 - - - - ko00000 - - - DUF418 HPHIIJEP_03511 224308.BSU26430 7.15e-164 458.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,1ZCRU@1386|Bacillus 91061|Bacilli T Transcriptional regulator yrkP - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_03512 224308.BSU26420 2.45e-304 830.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,1UIF3@1239|Firmicutes,4HHMV@91061|Bacilli,1ZF3Q@1386|Bacillus 91061|Bacilli T Histidine kinase yrkQ - - - - - - - - - - - HisKA HPHIIJEP_03513 224308.BSU26410 2.15e-90 265.0 COG3223@1|root,COG3223@2|Bacteria,1VCG5@1239|Firmicutes,4HKQN@91061|Bacilli,1ZI7B@1386|Bacillus 91061|Bacilli S Protein PsiE homolog psiE - - ko:K13256 - - - - ko00000 - - - PsiE HPHIIJEP_03514 224308.BSU25770 1.74e-14 73.2 COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,4HB3H@91061|Bacilli,1ZBV3@1386|Bacillus 91061|Bacilli L Recombinase - GO:0000150,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - ko:K06400 - - - - ko00000 - - - Recombinase,Resolvase,Zn_ribbon_recom HPHIIJEP_03515 1051501.AYTL01000030_gene2744 7.53e-161 452.0 COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,4HBY2@91061|Bacilli,1ZB3Q@1386|Bacillus 91061|Bacilli K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigK GO:0000003,GO:0000988,GO:0000990,GO:0003674,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043934,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 HPHIIJEP_03516 224308.BSU25750 2.53e-97 282.0 COG3209@1|root,COG3209@2|Bacteria,1V89J@1239|Firmicutes,4HJVE@91061|Bacilli,1ZH27@1386|Bacillus 91061|Bacilli M Deoxyribonuclease NucA/NucB nucB GO:0005575,GO:0005576 - - - - - - - - - - DNase_NucA_NucB HPHIIJEP_03517 224308.BSU25740 2.12e-167 468.0 28NWW@1|root,2ZBUP@2|Bacteria,1V3CS@1239|Firmicutes,4HGW3@91061|Bacilli,1ZQK7@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03518 224308.BSU25730 8.54e-214 590.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,1ZS1B@1386|Bacillus 91061|Bacilli G 6-phosphogluconate dehydrogenase yqeC - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 HPHIIJEP_03519 224308.BSU25720 3.81e-134 381.0 COG0398@1|root,COG0398@2|Bacteria,1VIP7@1239|Firmicutes,4HK4G@91061|Bacilli,1ZRQW@1386|Bacillus 91061|Bacilli S SNARE associated Golgi protein yqeD - - - - - - - - - - - SNARE_assoc HPHIIJEP_03520 224308.BSU25710 8.35e-177 493.0 COG3409@1|root,COG5632@1|root,COG3409@2|Bacteria,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,4HJ9N@91061|Bacilli,1ZB8D@1386|Bacillus 91061|Bacilli M n-acetylmuramoyl-L-alanine amidase xlyA - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2,PG_binding_1,SLH HPHIIJEP_03521 224308.BSU25700 5.27e-181 503.0 COG2755@1|root,COG2755@2|Bacteria,1U232@1239|Firmicutes,4IPYB@91061|Bacilli,1ZF2H@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase yqeF - - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_03523 224308.BSU25680 2.17e-123 351.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,1ZFKN@1386|Bacillus 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase HPHIIJEP_03524 224308.BSU25670 4.78e-273 746.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,1ZBES@1386|Bacillus 91061|Bacilli S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 HPHIIJEP_03525 224308.BSU25660 4.68e-198 549.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N HPHIIJEP_03526 224308.BSU25650 8.95e-61 187.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,1ZH83@1386|Bacillus 91061|Bacilli J RNA-binding protein containing KH domain, possibly ribosomal protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY HPHIIJEP_03527 224308.BSU25640 2.47e-141 398.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,1ZFIV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like HPHIIJEP_03528 224308.BSU25630 3.95e-132 374.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,1ZCQJ@1386|Bacillus 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD HPHIIJEP_03529 224308.BSU25620 1.39e-81 241.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,1ZGYR@1386|Bacillus 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS HPHIIJEP_03530 224308.BSU25610 5.67e-178 495.0 COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,4HD2W@91061|Bacilli,1ZB0Y@1386|Bacillus 91061|Bacilli Q Methyltransferase yqeM - - - - - - - - - - - Methyltransf_25 HPHIIJEP_03531 224308.BSU25600 1.1e-188 525.0 COG0345@1|root,COG0345@2|Bacteria,1UZ3D@1239|Firmicutes,4HCJ6@91061|Bacilli,1ZBFA@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline comER - - ko:K02239 - M00429 - - ko00000,ko00002,ko02044 - - - F420_oxidored,P5CR_dimer HPHIIJEP_03532 224308.BSU25590 1.5e-134 382.0 COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,1ZH4N@1386|Bacillus 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB HPHIIJEP_03533 224308.BSU25580 3.25e-137 387.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HEJU@91061|Bacilli,1ZQ4K@1386|Bacillus 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 HPHIIJEP_03534 224308.BSU25570 0.0 1429.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B HPHIIJEP_03535 224308.BSU25569 2.36e-22 86.3 2EJUP@1|root,33DJB@2|Bacteria,1VMIR@1239|Firmicutes,4HRA6@91061|Bacilli,1ZK02@1386|Bacillus 91061|Bacilli S YqzM-like protein - - - - - - - - - - - - YqzM HPHIIJEP_03536 224308.BSU25560 9.55e-243 667.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,1ZBST@1386|Bacillus 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta HPHIIJEP_03537 224308.BSU25550 4e-49 157.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,1ZI3X@1386|Bacillus 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p HPHIIJEP_03538 224308.BSU25540 3.42e-258 708.0 COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,4HAGH@91061|Bacilli,1ZC4A@1386|Bacillus 91061|Bacilli C Initiates the rapid degradation of small, acid-soluble proteins during spore germination gpr GO:0000003,GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019954,GO:0030436,GO:0032502,GO:0043170,GO:0043934,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.24.78 ko:K06012 - - - - ko00000,ko01000,ko01002 - - - Peptidase_A25 HPHIIJEP_03539 224308.BSU25530 2.73e-283 775.0 COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,4HACZ@91061|Bacilli,1ZAV0@1386|Bacillus 91061|Bacilli M stage II sporulation protein P spoIIP - - ko:K06385 - - - - ko00000 - - - SpoIIP HPHIIJEP_03540 224308.BSU25520 1.17e-68 208.0 2C4MB@1|root,345EE@2|Bacteria,1W0SN@1239|Firmicutes,4HP0K@91061|Bacilli,1ZJ36@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3679) yqxA - - - - - - - - - - - DUF3679 HPHIIJEP_03541 224308.BSU25510 0.0 1183.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C HPHIIJEP_03542 224308.BSU25500 1.13e-273 748.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,1ZC7V@1386|Bacillus 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM HPHIIJEP_03543 224308.BSU25490 1.65e-241 664.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,1ZBQV@1386|Bacillus 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg HPHIIJEP_03544 224308.BSU25480 4.36e-116 334.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,1ZGCW@1386|Bacillus 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE HPHIIJEP_03545 224308.BSU25470 0.0 1145.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,1ZAZ2@1386|Bacillus 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 HPHIIJEP_03546 224308.BSU25460 3.41e-257 706.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,1ZC0R@1386|Bacillus 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG HPHIIJEP_03547 224308.BSU25450 2.2e-223 615.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,1ZB7J@1386|Bacillus 91061|Bacilli J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA HPHIIJEP_03548 224308.BSU25440 2.79e-178 497.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,1ZAV7@1386|Bacillus 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA HPHIIJEP_03549 224308.BSU25430 0.0 898.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,1ZB8Q@1386|Bacillus 91061|Bacilli J ribosomal protein S12 methylthiotransferase yqeV GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 HPHIIJEP_03550 224308.BSU25420 3.26e-201 559.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli,1ZBHZ@1386|Bacillus 91061|Bacilli P COG1283 Na phosphate symporter yqeW - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans HPHIIJEP_03551 1178537.BA1_04662 1.03e-26 98.2 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,1ZJ3R@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 HPHIIJEP_03552 224308.BSU25400 2.25e-90 266.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,1ZGGX@1386|Bacillus 91061|Bacilli S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY HPHIIJEP_03553 224308.BSU25390 4.41e-289 792.0 COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,4H9P9@91061|Bacilli,1ZCTF@1386|Bacillus 91061|Bacilli O COG1030 Membrane-bound serine protease (ClpP class) yqeZ - - ko:K07403 - - - - ko00000 - - - NfeD,SDH_sah HPHIIJEP_03554 224308.BSU25380 4.35e-192 538.0 COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus 91061|Bacilli S UPF0365 protein yqfA - - - - - - - - - - - YdfA_immunity HPHIIJEP_03555 224308.BSU25370 2.57e-78 234.0 29RH9@1|root,30CK6@2|Bacteria,1UA17@1239|Firmicutes,4IK9T@91061|Bacilli,1ZG2T@1386|Bacillus 91061|Bacilli - - yqfB - - - - - - - - - - - - HPHIIJEP_03556 224308.BSU25360 2.07e-60 186.0 2E4EZ@1|root,32ZA5@2|Bacteria,1VF5C@1239|Firmicutes,4HNQG@91061|Bacilli,1ZHZA@1386|Bacillus 91061|Bacilli S sporulation protein YqfC yqfC - - - - - - - - - - - YabP HPHIIJEP_03557 224308.BSU25350 1.04e-242 672.0 COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,4HC8P@91061|Bacilli,1ZBP7@1386|Bacillus 91061|Bacilli S Stage IV sporulation yqfD - - ko:K06438 - - - - ko00000 - - - YqfD HPHIIJEP_03558 224308.BSU25340 4.99e-224 618.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,1ZBVE@1386|Bacillus 91061|Bacilli T Phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH HPHIIJEP_03560 224308.BSU25330 0.0 1300.0 COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,4HAEZ@91061|Bacilli,1ZANS@1386|Bacillus 91061|Bacilli S membrane-associated HD superfamily hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD HPHIIJEP_03561 224308.BSU25320 8.68e-106 305.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,1ZG7I@1386|Bacillus 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 HPHIIJEP_03562 224308.BSU25310 2.75e-79 236.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,1ZHW0@1386|Bacillus 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar HPHIIJEP_03563 224308.BSU25300 6.71e-93 271.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,1ZG79@1386|Bacillus 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009972,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - iYO844.BSU25300 dCMP_cyt_deam_1 HPHIIJEP_03564 224308.BSU25290 9.98e-215 593.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 HPHIIJEP_03565 224308.BSU25289 5.29e-27 98.2 2DKK1@1|root,309RW@2|Bacteria,1U5JZ@1239|Firmicutes,4IFAR@91061|Bacilli,1ZK2R@1386|Bacillus 91061|Bacilli S YqzL-like protein - - - - - - - - - - - - YqzL HPHIIJEP_03566 224308.BSU25280 7.48e-187 518.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,1ZAUA@1386|Bacillus 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N HPHIIJEP_03567 224308.BSU25270 2.12e-222 612.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,1ZCKP@1386|Bacillus 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e HPHIIJEP_03568 224308.BSU25260 0.0 1324.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,1ZDF3@1386|Bacillus 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f HPHIIJEP_03569 224308.BSU25250 3.29e-144 407.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,1ZB0P@1386|Bacillus 91061|Bacilli K CBS domain ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 HPHIIJEP_03570 224308.BSU25240 6.38e-191 530.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,1ZBIT@1386|Bacillus 91061|Bacilli S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase HPHIIJEP_03571 224308.BSU25230 6.03e-114 327.0 COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,4HM1G@91061|Bacilli,1ZFK7@1386|Bacillus 91061|Bacilli S Belongs to the UPF0178 family yqxD - - ko:K09768 - - - - ko00000 - - - DUF188 HPHIIJEP_03572 224308.BSU25210 0.0 1172.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,1ZC16@1386|Bacillus 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 HPHIIJEP_03573 1051501.AYTL01000030_gene2689 2.79e-254 699.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,1ZAV8@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 HPHIIJEP_03574 224308.BSU25190 1.61e-81 241.0 COG2010@1|root,COG2010@2|Bacteria,1VA0V@1239|Firmicutes,4HKF3@91061|Bacilli,1ZHVP@1386|Bacillus 91061|Bacilli C COG2010 Cytochrome c, mono- and diheme variants cccA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13300 - - - - ko00000 - - - Cytochrome_CBB3 HPHIIJEP_03575 224308.BSU25180 1.63e-148 418.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,1ZE5B@1386|Bacillus 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK HPHIIJEP_03576 224308.BSU25170 3.61e-267 731.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,1ZAPV@1386|Bacillus 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 HPHIIJEP_03577 224308.BSU25160 1.75e-226 624.0 COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9S4@91061|Bacilli,1ZAUG@1386|Bacillus 91061|Bacilli IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB HPHIIJEP_03578 224308.BSU25150 6.47e-53 178.0 2ECSV@1|root,336QF@2|Bacteria,1VFWG@1239|Firmicutes,4HP8Y@91061|Bacilli,1ZIWT@1386|Bacillus 91061|Bacilli S YqfQ-like protein yqfQ - - - - - - - - - - - YqfQ HPHIIJEP_03579 224308.BSU25140 1.09e-310 847.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,1ZDG5@1386|Bacillus 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C HPHIIJEP_03580 224308.BSU25130 1.04e-214 592.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,1ZBYQ@1386|Bacillus 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 HPHIIJEP_03581 224308.BSU25120 3.01e-49 157.0 2E5RP@1|root,330GA@2|Bacteria,1VI20@1239|Firmicutes,4HPUF@91061|Bacilli,1ZIUK@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2624) yqfT - - - - - - - - - - - DUF2624 HPHIIJEP_03582 224308.BSU25110 3.83e-199 553.0 COG1284@1|root,COG1284@2|Bacteria,1TQTP@1239|Firmicutes,4HBV2@91061|Bacilli,1ZCF3@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) yqfU - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_03583 224308.BSU25100 4.98e-106 305.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,1ZG74@1386|Bacillus 91061|Bacilli P Belongs to the Fur family zur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02076 - - - - ko00000,ko03000 - - - FUR HPHIIJEP_03584 224308.BSU25090 8.25e-142 399.0 COG5663@1|root,COG5663@2|Bacteria,1V2IT@1239|Firmicutes,4HG86@91061|Bacilli,1ZDPA@1386|Bacillus 91061|Bacilli S Belongs to the 5'(3')-deoxyribonucleotidase family yqfW - - ko:K05967 - - - - ko00000 - - - NT5C HPHIIJEP_03585 224308.BSU25080 2.04e-81 241.0 COG4709@1|root,COG4709@2|Bacteria,1VEVX@1239|Firmicutes,4HP5D@91061|Bacilli,1ZIJI@1386|Bacillus 91061|Bacilli S membrane yqfX - - - - - - - - - - - - HPHIIJEP_03586 224308.BSU25070 5.22e-257 706.0 COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H9S1@91061|Bacilli,1ZCV1@1386|Bacillus 91061|Bacilli I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE HPHIIJEP_03587 224308.BSU25060 1.35e-61 189.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain yqfZ - - ko:K06417 - - - - ko00000 - - - LysM HPHIIJEP_03588 224308.BSU25050 8.33e-99 286.0 28U06@1|root,2ZSTF@2|Bacteria,1W475@1239|Firmicutes,4I0TG@91061|Bacilli 91061|Bacilli - - yqgA - - - - - - - - - - - - HPHIIJEP_03589 224308.BSU25040 7.62e-171 478.0 COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,1ZBMN@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1189) yqgB - - - - - - - - - - - DUF1189 HPHIIJEP_03590 224308.BSU25030 8.25e-101 293.0 COG2839@1|root,COG2839@2|Bacteria,1V5DQ@1239|Firmicutes,4HHFQ@91061|Bacilli,1ZGBY@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqgC - - ko:K09793 - - - - ko00000 - - - DUF456 HPHIIJEP_03591 224308.BSU25020 1.59e-148 417.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus 91061|Bacilli P radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N HPHIIJEP_03592 224308.BSU25010 3.96e-293 802.0 COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli,1ZAQ7@1386|Bacillus 91061|Bacilli EGP Major facilitator superfamily yqgE - - ko:K08222 - - - - ko00000,ko02000 2.A.1.33 - - MFS_1 HPHIIJEP_03593 224308.BSU25000 0.0 1362.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,1ZBJM@1386|Bacillus 91061|Bacilli M penicillin-binding protein pbpA - - ko:K21465,ko:K21466 ko00550,map00550 - - - ko00000,ko00001,ko01011 - - - PBP_dimer,Transpeptidase HPHIIJEP_03594 224308.BSU24990 1.06e-204 567.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,1ZB22@1386|Bacillus 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 HPHIIJEP_03595 224308.BSU24980 7.11e-203 563.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,1ZAUU@1386|Bacillus 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 HPHIIJEP_03596 224308.BSU24970 5.26e-202 560.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,1ZDAY@1386|Bacillus 91061|Bacilli P Phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 HPHIIJEP_03597 224308.BSU24960 3.98e-189 525.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstBA - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran HPHIIJEP_03598 224308.BSU24950 1.57e-186 518.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,1ZBQ5@1386|Bacillus 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - iSB619.SA_RS06920 ABC_tran HPHIIJEP_03599 224308.BSU24940 9e-93 272.0 COG1559@1|root,COG1559@2|Bacteria,1VF1E@1239|Firmicutes,4HQ19@91061|Bacilli,1ZQS7@1386|Bacillus 91061|Bacilli S YceG-like family yqzC - - - - - - - - - - - YceG HPHIIJEP_03600 224308.BSU24930 3.42e-68 207.0 2E4ER@1|root,32Z9X@2|Bacteria,1VGCA@1239|Firmicutes,4HS6U@91061|Bacilli,1ZJ5Y@1386|Bacillus 91061|Bacilli - - yqzD - - - - - - - - - - - Sigma70_r4_2 HPHIIJEP_03602 224308.BSU24910 1.37e-248 683.0 COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,4HE1F@91061|Bacilli,1ZS6K@1386|Bacillus 91061|Bacilli M Glycosyl transferases group 1 yqgM - 2.4.1.250 ko:K15521 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 HPHIIJEP_03603 224308.BSU24900 6.25e-29 103.0 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,1ZIUS@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 HPHIIJEP_03604 224308.BSU24890 2.57e-133 377.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,1ZH1W@1386|Bacillus 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig HPHIIJEP_03605 279010.BL05268 3.38e-14 66.6 2BF3K@1|root,328VQ@2|Bacteria,1UB73@1239|Firmicutes,4IMJT@91061|Bacilli,1ZKBA@1386|Bacillus 91061|Bacilli - - yqgO - - - - - - - - - - - - HPHIIJEP_03606 224308.BSU24870 0.0 901.0 COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,1ZBV7@1386|Bacillus 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 HPHIIJEP_03607 224308.BSU24860 1.27e-43 142.0 COG4483@1|root,COG4483@2|Bacteria 2|Bacteria S Protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 HPHIIJEP_03608 224308.BSU24850 2.31e-230 634.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,1ZBV8@1386|Bacillus 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK HPHIIJEP_03609 224308.BSU24840 0.0 1248.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,1ZBBV@1386|Bacillus 91061|Bacilli M Belongs to the LTA synthase family yqgS GO:0005575,GO:0005576 2.7.8.20 ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase HPHIIJEP_03610 224308.BSU24830 8.36e-281 766.0 COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,4HAHN@91061|Bacilli,1ZD1J@1386|Bacillus 91061|Bacilli E Gamma-D-glutamyl-L-diamino acid endopeptidase yqgT GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.11 ko:K01308 - - - - ko00000,ko01000,ko01002 - - - LysM,Peptidase_M14 HPHIIJEP_03611 224308.BSU24820 9.37e-257 703.0 2BAY9@1|root,324E2@2|Bacteria,1V8TN@1239|Firmicutes,4HJ42@91061|Bacilli,1ZESD@1386|Bacillus 91061|Bacilli - - yqgU - - - - - - - - - - - - HPHIIJEP_03612 224308.BSU24810 7.34e-66 200.0 COG0011@1|root,COG0011@2|Bacteria,1VC84@1239|Firmicutes,4HMNH@91061|Bacilli,1ZRYU@1386|Bacillus 91061|Bacilli S Thiamine-binding protein yqgV GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Thiamine_BP HPHIIJEP_03613 224308.BSU24800 1.91e-31 110.0 2ES0W@1|root,306VH@2|Bacteria,1VET3@1239|Firmicutes,4I9TK@91061|Bacilli,1ZK2C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2759) yqgW - - - - - - - - - - - DUF2759 HPHIIJEP_03614 224308.BSU24790 1.07e-155 436.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli,1ZC72@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B HPHIIJEP_03615 1051501.AYTL01000030_gene2647 1.46e-50 160.0 2E1GI@1|root,32WUX@2|Bacteria,1VB9C@1239|Firmicutes,4HKV2@91061|Bacilli,1ZQN8@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2626) yqgY - - - - - - - - - - - DUF2626 HPHIIJEP_03616 224308.BSU24770 7.79e-85 250.0 COG1393@1|root,COG1393@2|Bacteria,1V73M@1239|Firmicutes,4HJDP@91061|Bacilli,1ZHC6@1386|Bacillus 91061|Bacilli P Belongs to the ArsC family yqgZ - 1.20.4.1 ko:K00537,ko:K16509 - - - - ko00000,ko01000 - - - ArsC HPHIIJEP_03618 224308.BSU24760 8.33e-191 530.0 COG1366@1|root,COG1366@2|Bacteria,1V326@1239|Firmicutes,4HGFQ@91061|Bacilli,1ZPXD@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) yqhA - - ko:K17763 - - - - ko00000,ko03021 - - - RsbRD_N,STAS HPHIIJEP_03619 224308.BSU24750 1.16e-304 832.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,1ZBAN@1386|Bacillus 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains yqhB - - - - - - - - - - - CBS,CorC_HlyC,DUF21 HPHIIJEP_03620 224308.BSU24740 8.37e-231 635.0 COG0598@1|root,COG0598@2|Bacteria,1UZTE@1239|Firmicutes,4HDNF@91061|Bacilli,1ZD16@1386|Bacillus 91061|Bacilli P Mg2 transporter protein yqxL GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - CorA HPHIIJEP_03621 935837.JAEK01000023_gene1204 5.34e-06 48.1 COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4HHZP@91061|Bacilli,1ZH84@1386|Bacillus 91061|Bacilli S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS HPHIIJEP_03622 224308.BSU24730 5.23e-256 702.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,1ZBK5@1386|Bacillus 91061|Bacilli NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE HPHIIJEP_03623 224308.BSU24720 2.5e-218 605.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,1ZCQK@1386|Bacillus 91061|Bacilli NU COG1459 Type II secretory pathway, component PulF comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF HPHIIJEP_03624 224308.BSU24710 5.33e-63 192.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli,1ZIXK@1386|Bacillus 91061|Bacilli U Required for transformation and DNA binding comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl HPHIIJEP_03625 224308.BSU24700 5.81e-86 254.0 COG4970@1|root,COG4970@2|Bacteria 2|Bacteria NU protein transport across the cell outer membrane gspH - - ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 M00331,M00429 - - ko00000,ko00001,ko00002,ko02035,ko02044 3.A.15,3.A.15.2 - - GspH,N_methyl HPHIIJEP_03626 224308.BSU24690 1.77e-78 233.0 2A141@1|root,30P9X@2|Bacteria,1U27V@1239|Firmicutes,4IBS2@91061|Bacilli,1ZHEW@1386|Bacillus 91061|Bacilli - - comGE - - ko:K02247 - M00429 - - ko00000,ko00002,ko02044 - - - - HPHIIJEP_03627 224308.BSU24680 7.11e-47 152.0 COG4940@1|root,COG4940@2|Bacteria 2|Bacteria U Putative Competence protein ComGF comGF - - ko:K02246,ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl HPHIIJEP_03628 1051501.AYTL01000030_gene2635 1.88e-57 181.0 2BH1G@1|root,32B1U@2|Bacteria,1UB30@1239|Firmicutes,4IMFQ@91061|Bacilli,1ZK26@1386|Bacillus 91061|Bacilli S ComG operon protein 7 - - - ko:K02249 - M00429 - - ko00000,ko00002,ko02044 - - - ComGG HPHIIJEP_03629 224308.BSU24660 2.84e-36 122.0 2EKZB@1|root,33ENU@2|Bacteria,1VM73@1239|Firmicutes,4HR7F@91061|Bacilli,1ZJY6@1386|Bacillus 91061|Bacilli S YqzE-like protein yqzE - - - - - - - - - - - YqzE HPHIIJEP_03630 224308.BSU24650 4.33e-69 209.0 29KX1@1|root,307UH@2|Bacteria,1U288@1239|Firmicutes,4IBSK@91061|Bacilli,1ZHFX@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3889) yqzG - - - - - - - - - - - DUF3889 HPHIIJEP_03631 224308.BSU24640 1.04e-151 429.0 29RGE@1|root,30CJ7@2|Bacteria,1U9ZM@1239|Firmicutes,4IK7R@91061|Bacilli,1ZFNP@1386|Bacillus 91061|Bacilli - - yqxM - - ko:K19433 - - - - ko00000 - - - - HPHIIJEP_03632 224308.BSU24630 7.4e-98 288.0 COG0681@1|root,COG0681@2|Bacteria,1VH6F@1239|Firmicutes,4HJZA@91061|Bacilli,1ZRQY@1386|Bacillus 91061|Bacilli U Signal peptidase sipW GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 3.4.21.89 ko:K13280 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 HPHIIJEP_03633 224308.BSU24620 3.14e-182 507.0 2CA96@1|root,2ZBTW@2|Bacteria,1V2TR@1239|Firmicutes,4HGFJ@91061|Bacilli,1ZC8Q@1386|Bacillus 91061|Bacilli S Cell division protein FtsN tasA_1 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06336 - - - - ko00000,ko01002 - - - Peptidase_M73 HPHIIJEP_03634 1051501.AYTL01000030_gene2630 3.69e-72 217.0 COG1396@1|root,COG1396@2|Bacteria,1VAXE@1239|Firmicutes,4HKHB@91061|Bacilli,1ZHZH@1386|Bacillus 91061|Bacilli K transcriptional sinR GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - ko:K19449 - - - - ko00000,ko03000 - - - HTH_3,SinI HPHIIJEP_03635 224308.BSU24600 1.39e-33 115.0 29S6X@1|root,30DBE@2|Bacteria,1UB3V@1239|Firmicutes,4IMGG@91061|Bacilli,1ZK3S@1386|Bacillus 91061|Bacilli S Anti-repressor SinI sinI - - ko:K06372 - - - - ko00000 - - - SinI HPHIIJEP_03636 224308.BSU24590 5.08e-194 537.0 2CH5D@1|root,2Z821@2|Bacteria,1TS45@1239|Firmicutes,4HCE9@91061|Bacilli,1ZAXP@1386|Bacillus 91061|Bacilli S Bacterial protein YqhG of unknown function yqhG - - - - - - - - - - - YqhG HPHIIJEP_03637 224308.BSU24580 0.0 1097.0 COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,4H9WB@91061|Bacilli,1ZAR5@1386|Bacillus 91061|Bacilli L COG0553 Superfamily II DNA RNA helicases, SNF2 family yqhH - - - - - - - - - - - Helicase_C,SNF2_N HPHIIJEP_03638 224308.BSU24570 5.49e-261 715.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C HPHIIJEP_03639 224308.BSU24560 0.0 874.0 COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,1ZB0H@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P HPHIIJEP_03640 224308.BSU24550 0.0 983.0 COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,1ZATI@1386|Bacillus 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P HPHIIJEP_03641 224308.BSU24540 7.5e-83 245.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,1ZGZX@1386|Bacillus 91061|Bacilli P COG0607 Rhodanese-related sulfurtransferase yqhL - - - - - - - - - - - Rhodanese HPHIIJEP_03642 224308.BSU24530 3.73e-203 561.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,1ZBG2@1386|Bacillus 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB HPHIIJEP_03643 224308.BSU24520 1.97e-97 283.0 COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,1ZFKR@1386|Bacillus 91061|Bacilli K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA HPHIIJEP_03644 224308.BSU24510 1.21e-210 582.0 COG1752@1|root,COG1752@2|Bacteria,1TRJW@1239|Firmicutes,4HB8J@91061|Bacilli,1ZC13@1386|Bacillus 91061|Bacilli S esterase of the alpha-beta hydrolase superfamily yqhO GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin HPHIIJEP_03645 224308.BSU24500 5.18e-81 241.0 2BYG1@1|root,33M6N@2|Bacteria,1U3TH@1239|Firmicutes,4IC1U@91061|Bacilli,1ZIYH@1386|Bacillus 91061|Bacilli - - yqhP - - - - - - - - - - - - HPHIIJEP_03646 224308.BSU24490 3.48e-219 605.0 COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H9KN@91061|Bacilli,1ZBXJ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1385) yqhQ - - - - - - - - - - - DUF1385 HPHIIJEP_03647 224308.BSU24480 1.33e-119 342.0 29VNZ@1|root,30H6A@2|Bacteria,1V5PG@1239|Firmicutes,4HJV5@91061|Bacilli,1ZBD8@1386|Bacillus 91061|Bacilli S Conserved membrane protein YqhR yqhR - - - - - - - - - - - YqhR HPHIIJEP_03648 224308.BSU24470 1.17e-101 294.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,4HJ2V@91061|Bacilli,1ZG8H@1386|Bacillus 91061|Bacilli E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II HPHIIJEP_03649 224308.BSU24460 8.58e-249 683.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,1ZB4P@1386|Bacillus 91061|Bacilli E COG0006 Xaa-Pro aminopeptidase yqhT - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 HPHIIJEP_03650 224308.BSU24450 4.8e-128 364.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,1ZAT9@1386|Bacillus 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C HPHIIJEP_03651 224308.BSU24440 6.96e-50 159.0 2E4CX@1|root,32Z8B@2|Bacteria,1VEW3@1239|Firmicutes,4HNU3@91061|Bacilli,1ZIYG@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2619) yqhV - - - - - - - - - - - DUF2619 HPHIIJEP_03652 224308.BSU24430 8.22e-217 598.0 COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,4HA2K@91061|Bacilli,1ZAWB@1386|Bacillus 91061|Bacilli S stage III sporulation protein AA spoIIIAA - - ko:K06390 - - - - ko00000 - - - AAA,T2SSE HPHIIJEP_03653 224308.BSU24420 3.29e-110 318.0 2CEWW@1|root,32S0Q@2|Bacteria,1VAEG@1239|Firmicutes,4HGSK@91061|Bacilli,1ZQIX@1386|Bacillus 91061|Bacilli S Stage III sporulation protein spoIIIAB - - ko:K06391 - - - - ko00000 - - - Spore_III_AB HPHIIJEP_03654 1051501.AYTL01000030_gene2610 1.63e-39 131.0 2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,4HNG4@91061|Bacilli,1ZQSJ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AC spoIIIAC - - ko:K06392 - - - - ko00000 - - - SpoIIIAC HPHIIJEP_03655 224308.BSU24400 1.93e-77 232.0 2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,4HIIH@91061|Bacilli,1ZGYV@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AD spoIIIAD - - ko:K06393 - - - - ko00000 - - - SpoIIIAC HPHIIJEP_03656 224308.BSU24390 7.65e-257 707.0 2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,4H9UX@91061|Bacilli,1ZCFI@1386|Bacillus 91061|Bacilli S stage III sporulation protein AE spoIIIAE - - ko:K06394 - - - - ko00000 - - - Spore_III_AE HPHIIJEP_03657 224308.BSU24380 1.28e-131 375.0 2E7KE@1|root,3322G@2|Bacteria,1VIAM@1239|Firmicutes,4HPYJ@91061|Bacilli,1ZS0K@1386|Bacillus 91061|Bacilli S Stage III sporulation protein AF (Spore_III_AF) spoIIIAF - - ko:K06395 - - - - ko00000 - - - Spore_III_AF HPHIIJEP_03658 224308.BSU24370 1.53e-148 419.0 2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,4HH7J@91061|Bacilli,1ZEMQ@1386|Bacillus 91061|Bacilli S stage III sporulation protein AG spoIIIAG - - ko:K06396 - - - - ko00000 - - - - HPHIIJEP_03659 224308.BSU24360 9.92e-135 384.0 29WYG@1|root,30IKQ@2|Bacteria,1V4Y2@1239|Firmicutes,4HI5K@91061|Bacilli,1ZHEH@1386|Bacillus 91061|Bacilli S SpoIIIAH-like protein spoIIIAH - - ko:K06397 - - - - ko00000 1.A.34.1.1 - - SpoIIIAH HPHIIJEP_03660 224308.BSU24350 3.21e-93 274.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,1ZGFF@1386|Bacillus 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl HPHIIJEP_03661 224308.BSU24340 0.0 885.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,1ZC56@1386|Bacillus 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 HPHIIJEP_03662 224308.BSU24330 1.65e-88 260.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,1ZG6N@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqhY - - - - - - - - - - - Asp23 HPHIIJEP_03663 224308.BSU24320 4.8e-86 253.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB HPHIIJEP_03664 224308.BSU24310 1.07e-200 556.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C HPHIIJEP_03665 224308.BSU24300 3.55e-312 852.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,1ZB5Q@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 HPHIIJEP_03666 224308.BSU24290 1.09e-51 163.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,1ZIVS@1386|Bacillus 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S HPHIIJEP_03667 224308.BSU24280 4.2e-209 578.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,1ZC4G@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt HPHIIJEP_03668 224308.BSU24270 0.0 1273.0 COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H9QW@91061|Bacilli,1ZBHF@1386|Bacillus 91061|Bacilli H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C HPHIIJEP_03669 224308.BSU24260 1.77e-198 550.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,1ZBDS@1386|Bacillus 91061|Bacilli J rRNA methylase rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 HPHIIJEP_03670 224308.BSU24250 1.53e-102 296.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,1ZFJ8@1386|Bacillus 91061|Bacilli K Regulates arginine biosynthesis genes argR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C HPHIIJEP_03671 224308.BSU24240 0.0 1074.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,1ZC8B@1386|Bacillus 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N HPHIIJEP_03672 224308.BSU24230 5.12e-303 827.0 COG0750@1|root,COG0750@2|Bacteria,1TPIR@1239|Firmicutes,4H9TW@91061|Bacilli,1ZB04@1386|Bacillus 91061|Bacilli M Stage IV sporulation protein B spoIVB - 3.4.21.116 ko:K06399 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_S55 HPHIIJEP_03673 224308.BSU24220 1.89e-186 518.0 COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,4HA1M@91061|Bacilli,1ZBNB@1386|Bacillus 91061|Bacilli KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process spo0A GO:0000003,GO:0000156,GO:0000160,GO:0000910,GO:0003674,GO:0006355,GO:0007049,GO:0007154,GO:0007165,GO:0008150,GO:0008356,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0019954,GO:0022402,GO:0022603,GO:0022607,GO:0023052,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0032506,GO:0035556,GO:0042173,GO:0042710,GO:0043934,GO:0043937,GO:0043938,GO:0044010,GO:0044085,GO:0044764,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051171,GO:0051252,GO:0051301,GO:0051704,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090529,GO:0090604,GO:0090606,GO:1903506,GO:2000112,GO:2001141 - ko:K07699 ko02020,ko02024,map02020,map02024 M00485 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Spo0A_C HPHIIJEP_03675 224308.BSU24210 1.63e-272 745.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,1ZB1N@1386|Bacillus 91061|Bacilli C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family yqiG - - - - - - - - - - - Oxidored_FMN HPHIIJEP_03676 720555.BATR1942_10405 6.47e-37 127.0 2E29G@1|root,32XF4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - PrcB_C HPHIIJEP_03677 224308.BSU24190 5.67e-139 393.0 COG0860@1|root,COG0860@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,1ZPUS@1386|Bacillus 91061|Bacilli M Cell wall hydrolase autolysin lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH HPHIIJEP_03678 224308.BSU24180 3.39e-168 470.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1ZFB8@1386|Bacillus 91061|Bacilli C glycerophosphoryl diester phosphodiesterase yqiK - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD HPHIIJEP_03679 224308.BSU24170 2.06e-67 214.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N HPHIIJEP_03680 224308.BSU24170 5.83e-195 545.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZB7V@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N HPHIIJEP_03681 224308.BSU24160 9.4e-197 546.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZAYV@1386|Bacillus 91061|Bacilli I Dehydrogenase mmgB - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N HPHIIJEP_03682 224308.BSU24150 1.42e-267 733.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,1ZBG3@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase mmgC - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N HPHIIJEP_03683 224308.BSU24140 1.85e-264 724.0 COG0372@1|root,COG0372@2|Bacteria,1TSRN@1239|Firmicutes,4HAZ9@91061|Bacilli,1ZC80@1386|Bacillus 91061|Bacilli C Belongs to the citrate synthase family mmgD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0071704 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt HPHIIJEP_03684 224308.BSU24130 0.0 949.0 COG2079@1|root,COG2079@2|Bacteria,1TRR8@1239|Firmicutes,4HAUS@91061|Bacilli,1ZCS6@1386|Bacillus 91061|Bacilli S 2-methylcitrate dehydratase prpD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD HPHIIJEP_03685 224308.BSU24120 5.09e-208 576.0 COG2513@1|root,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,4HCDV@91061|Bacilli,1ZR0A@1386|Bacillus 91061|Bacilli G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate prpB - 4.1.3.30,5.4.2.9 ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 - R00409,R00661 RC00286,RC00287,RC02792 ko00000,ko00001,ko01000 - - - PEP_mutase HPHIIJEP_03686 224308.BSU24110 1.56e-46 149.0 2E54T@1|root,32ZXQ@2|Bacteria,1VFDB@1239|Firmicutes,4HNU1@91061|Bacilli,1ZIWH@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2627) yqzF - - - - - - - - - - - DUF2627 HPHIIJEP_03687 224308.BSU24100 0.0 1341.0 COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,1ZAZA@1386|Bacillus 91061|Bacilli KT Transcriptional regulator bkdR - - - - - - - - - - - DapB_N,HTH_8,PAS,Sigma54_activat HPHIIJEP_03688 224308.BSU24090 5e-198 550.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,1ZC49@1386|Bacillus 91061|Bacilli C phosphate butyryltransferase ptb - 2.3.1.19 ko:K00634 ko00650,ko01100,map00650,map01100 - R01174 RC00004,RC02816 ko00000,ko00001,ko01000 - - iYO844.BSU24090 PTA_PTB HPHIIJEP_03689 224308.BSU24080 1.92e-262 719.0 COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family ldh - 1.4.1.9 ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 - R01088,R01434,R02196 RC00006,RC00036 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HPHIIJEP_03690 224308.BSU24070 1.18e-255 701.0 COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,1ZC7E@1386|Bacillus 91061|Bacilli C Belongs to the acetokinase family buk - 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 - R01688 RC00002,RC00043 ko00000,ko00001,ko01000 - - - Acetate_kinase HPHIIJEP_03691 224308.BSU24060 0.0 928.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,1ZBCS@1386|Bacillus 91061|Bacilli C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes bfmBC - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim HPHIIJEP_03692 224308.BSU24050 1.92e-238 655.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,1ZCCJ@1386|Bacillus 91061|Bacilli C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh HPHIIJEP_03693 224308.BSU24040 6.92e-235 646.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1ZC0X@1386|Bacillus 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit bfmBAB - 1.2.4.4 ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU24040 Transket_pyr,Transketolase_C HPHIIJEP_03694 224308.BSU24030 2.54e-286 784.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,1ZC6F@1386|Bacillus 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex bkdB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding HPHIIJEP_03695 224308.BSU24020 6.38e-195 541.0 COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V9GA@1239|Firmicutes,4IPYA@91061|Bacilli,1ZH1N@1386|Bacillus 91061|Bacilli K helix_turn_helix, mercury resistance - - - ko:K19575 - M00765 - - ko00000,ko00002,ko03000 - - - GyrI-like,MerR_1 HPHIIJEP_03696 224308.BSU24010 3.6e-266 730.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus 91061|Bacilli EGP COG0477 Permeases of the major facilitator superfamily norA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08153,ko:K19576,ko:K19578 - M00717,M00765 - - ko00000,ko00002,ko02000 2.A.1.2.10,2.A.1.2.70,2.A.1.2.8 - iYO844.BSU26590 MFS_1,MFS_1_like,Sugar_tr HPHIIJEP_03697 224308.BSU24000 1.21e-213 590.0 COG1597@1|root,COG1597@2|Bacteria,1TRGQ@1239|Firmicutes,4HDR5@91061|Bacilli,1ZCT6@1386|Bacillus 91061|Bacilli I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase bmrU - - - - - - - - - - - DAGK_cat HPHIIJEP_03698 224308.BSU23990 3.79e-101 293.0 28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZFKZ@1386|Bacillus 91061|Bacilli S Belongs to the UPF0403 family yqiW - - - - - - - - - - - Disulph_isomer HPHIIJEP_03699 224308.BSU23980 1.18e-174 488.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HU0X@91061|Bacilli,1ZRKX@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 HPHIIJEP_03700 224308.BSU23970 8.94e-143 404.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,1ZBUZ@1386|Bacillus 91061|Bacilli E COG0765 ABC-type amino acid transport system, permease component artQ GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 HPHIIJEP_03701 224308.BSU23960 5.2e-166 464.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus 91061|Bacilli E COG1126 ABC-type polar amino acid transport system, ATPase component artM - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran HPHIIJEP_03702 224308.BSU23950 1.73e-221 612.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,1ZBBI@1386|Bacillus 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C HPHIIJEP_03703 224308.BSU23940 3.43e-128 363.0 COG1376@1|root,COG1376@2|Bacteria,1V26F@1239|Firmicutes,4HG56@91061|Bacilli,1ZGC7@1386|Bacillus 91061|Bacilli S protein conserved in bacteria yqjB - - - - - - - - - - - YkuD HPHIIJEP_03705 224308.BSU23930 5.45e-94 274.0 COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4HCP5@91061|Bacilli,1ZHE7@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases mce - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 HPHIIJEP_03706 224308.BSU23920 0.0 985.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HC50@91061|Bacilli,1ZQ98@1386|Bacillus 91061|Bacilli I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) yqjD GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans HPHIIJEP_03707 224308.BSU23910 5.26e-259 711.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HA04@91061|Bacilli,1ZBSY@1386|Bacillus 91061|Bacilli E COG2195 Di- and tripeptidases yqjE - 3.4.11.14,3.4.11.4 ko:K01258,ko:K01263 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HPHIIJEP_03708 224308.BSU23900 1.57e-177 494.0 COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,1ZDFC@1386|Bacillus 91061|Bacilli S Uncharacterized conserved protein (COG2071) yqjF - - ko:K09166 - - - - ko00000 - - - DUF2071 HPHIIJEP_03709 224308.BSU23890 7.27e-179 500.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,1ZE6C@1386|Bacillus 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP HPHIIJEP_03710 1274524.BSONL12_07272 2.4e-30 110.0 29RSE@1|root,30CW5@2|Bacteria,1UAGA@1239|Firmicutes,4IKUQ@91061|Bacilli,1ZHPK@1386|Bacillus 91061|Bacilli - - yqzJ - - - - - - - - - - - - HPHIIJEP_03711 224308.BSU23870 1.84e-299 816.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,1ZAZZ@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH HPHIIJEP_03712 224308.BSU23860 0.0 924.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus 91061|Bacilli G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 HPHIIJEP_03713 224308.BSU23850 0.0 993.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,1ZCZ3@1386|Bacillus 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N HPHIIJEP_03714 224308.BSU23840 2.2e-221 610.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,1ZC3J@1386|Bacillus 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 HPHIIJEP_03715 326423.RBAM_022140 8.59e-27 97.8 COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,1ZIUS@1386|Bacillus 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 HPHIIJEP_03716 224308.BSU23830 1.29e-186 518.0 COG0596@1|root,COG0596@2|Bacteria,1V9D7@1239|Firmicutes,4HK54@91061|Bacilli,1ZEVK@1386|Bacillus 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) yqjL - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 HPHIIJEP_03717 224308.BSU23820 1.72e-245 674.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4H9YM@91061|Bacilli,1ZB4D@1386|Bacillus 91061|Bacilli C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes namA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 1.6.99.1 ko:K00354 - - R00282 RC00001 ko00000,ko01000 - - - Oxidored_FMN HPHIIJEP_03718 224308.BSU23810 0.0 1083.0 COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,4HABT@91061|Bacilli,1ZCEE@1386|Bacillus 91061|Bacilli E arginine degradation protein rocB - - - - - - - - - - - Peptidase_M20 HPHIIJEP_03719 224308.BSU23800 1.13e-188 525.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU18480 F420_oxidored,P5CR_dimer HPHIIJEP_03720 224308.BSU23790 1.28e-226 624.0 COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqjP - - - - - - - - - - - Lactamase_B HPHIIJEP_03721 224308.BSU23780 1.39e-184 513.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,1ZBRZ@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short HPHIIJEP_03722 224308.BSU23770 0.0 896.0 COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,4HANC@91061|Bacilli,1ZASU@1386|Bacillus 91061|Bacilli E Belongs to the serine threonine dehydratase family. DsdA subfamily dsdA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008721,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.18 ko:K01753 ko00260,map00260 - R00221 RC02600 ko00000,ko00001,ko01000 - - - PALP HPHIIJEP_03723 224308.BSU23760 1.89e-228 629.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,1ZB00@1386|Bacillus 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK HPHIIJEP_03724 224308.BSU23750 1.68e-28 104.0 COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli,1ZGG2@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yqjT - - - - - - - - - - - Glyoxalase,Glyoxalase_4 HPHIIJEP_03725 224308.BSU23750 5.6e-57 178.0 COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli,1ZGG2@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily yqjT - - - - - - - - - - - Glyoxalase,Glyoxalase_4 HPHIIJEP_03727 224308.BSU23730 1.38e-287 786.0 COG2211@1|root,COG2211@2|Bacteria,1UI4M@1239|Firmicutes,4ISD6@91061|Bacilli,1ZS7N@1386|Bacillus 91061|Bacilli G Major Facilitator Superfamily yqjV GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr HPHIIJEP_03729 224308.BSU23710 4.03e-304 828.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,1ZC8I@1386|Bacillus 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH HPHIIJEP_03730 1051501.AYTL01000030_gene2536 3.23e-66 202.0 2DQHI@1|root,336W6@2|Bacteria,1VM8Z@1239|Firmicutes,4HQJC@91061|Bacilli 91061|Bacilli S YolD-like protein yqiX - - - - - - - - - - - YolD HPHIIJEP_03731 224308.BSU23690 5.46e-113 323.0 COG0454@1|root,COG0456@2|Bacteria,1V50M@1239|Firmicutes,4HH63@91061|Bacilli,1ZG7D@1386|Bacillus 91061|Bacilli K acetyltransferase yqjY GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 HPHIIJEP_03732 224308.BSU23680 6.7e-73 219.0 COG2329@1|root,COG2329@2|Bacteria,1VAM1@1239|Firmicutes,4HJD7@91061|Bacilli,1ZHXP@1386|Bacillus 91061|Bacilli S enzyme involved in biosynthesis of extracellular polysaccharides yqjZ - - - - - - - - - - - ABM HPHIIJEP_03733 224308.BSU23670 4.59e-248 681.0 COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli,1ZHJE@1386|Bacillus 91061|Bacilli K GrpB protein yqkA - - - - - - - - - - - Acetyltransf_10,GrpB HPHIIJEP_03734 224308.BSU23660 6.17e-73 218.0 COG4918@1|root,COG4918@2|Bacteria,1VJ11@1239|Firmicutes,4HPA2@91061|Bacilli,1ZSK4@1386|Bacillus 91061|Bacilli S Belongs to the HesB IscA family yqkB - - - - - - - - - - - Fe-S_biosyn HPHIIJEP_03735 224308.BSU23650 1.12e-53 167.0 2FH9Z@1|root,34949@2|Bacteria,1VYS1@1239|Firmicutes,4HYMH@91061|Bacilli,1ZIBH@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2552) yqkC - - - - - - - - - - - DUF2552 HPHIIJEP_03736 224308.BSU23640 3.79e-219 604.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,1ZBDV@1386|Bacillus 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily yqkD - - ko:K06889 - - - - ko00000 - - - Hydrolase_4 HPHIIJEP_03737 224308.BSU23630 6.61e-26 97.4 2EGUT@1|root,30CDC@2|Bacteria,1U9P4@1239|Firmicutes,4HZT2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3886) yqkE - - - - - - - - - - - DUF3886 HPHIIJEP_03738 224308.BSU23620 1.04e-214 593.0 COG0667@1|root,COG0667@2|Bacteria,1TTT8@1239|Firmicutes,4H9XM@91061|Bacilli,1ZBYV@1386|Bacillus 91061|Bacilli C oxidoreductases (related to aryl-alcohol dehydrogenases) yqkF - - - - - - - - - - - Aldo_ket_red HPHIIJEP_03739 545693.BMQ_4402 8.21e-10 54.7 29S4Z@1|root,30D9H@2|Bacteria,1UB1A@1239|Firmicutes,4IME6@91061|Bacilli,1ZJXS@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3936) - - - - - - - - - - - - DUF3936 HPHIIJEP_03740 224308.BSU23610 4.07e-120 344.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,1ZFIW@1386|Bacillus 91061|Bacilli L Belongs to the Nudix hydrolase family nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX HPHIIJEP_03741 224308.BSU23600 2.93e-280 766.0 COG1379@1|root,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,4HCQ4@91061|Bacilli,1ZASI@1386|Bacillus 91061|Bacilli L DNA helicase yqxK - - - - - - - - - - - PHP_C HPHIIJEP_03742 224308.BSU23590 3.18e-77 230.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HM8Q@91061|Bacilli,1ZI74@1386|Bacillus 91061|Bacilli K Transcriptional regulator ansR - - - - - - - - - - - HTH_3 HPHIIJEP_03743 224308.BSU23580 1.77e-238 655.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4HD98@91061|Bacilli,1ZQ9H@1386|Bacillus 91061|Bacilli EJ L-asparaginase ansA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase HPHIIJEP_03744 224308.BSU23570 0.0 931.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus 91061|Bacilli E Aspartate ammonia-lyase aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 HPHIIJEP_03745 224308.BSU23560 1.14e-309 847.0 COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,4HA18@91061|Bacilli,1ZBQN@1386|Bacillus 91061|Bacilli C Na H antiporter mleN GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03315 - - - - ko00000,ko02000 2.A.35 - - Na_H_antiporter HPHIIJEP_03746 224308.BSU23550 2.78e-309 843.0 COG0281@1|root,COG0281@2|Bacteria,1UYHB@1239|Firmicutes,4HDRG@91061|Bacilli,1ZDC7@1386|Bacillus 91061|Bacilli C malic enzyme mleA - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - 2-Hacid_dh_C,ACT_4,Malic_M,THF_DHG_CYH_C,malic HPHIIJEP_03747 224308.BSU23540 7.27e-42 137.0 2B8M5@1|root,321WG@2|Bacteria,1UAP9@1239|Firmicutes,4IM1W@91061|Bacilli,1ZIS1@1386|Bacillus 91061|Bacilli - - yqkK - - - - - - - - - - - - HPHIIJEP_03748 224308.BSU23530 1.96e-139 395.0 COG1300@1|root,COG1300@2|Bacteria,1V81P@1239|Firmicutes,4HJW8@91061|Bacilli,1ZAYC@1386|Bacillus 91061|Bacilli S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane spoIIM GO:0005575,GO:0005623,GO:0008150,GO:0010564,GO:0022603,GO:0030428,GO:0032465,GO:0032467,GO:0032954,GO:0042173,GO:0043937,GO:0044087,GO:0044089,GO:0044464,GO:0045595,GO:0045787,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051302,GO:0051726,GO:0051781,GO:0065007,GO:0090068,GO:1901891,GO:1901893 - ko:K06384 - - - - ko00000 - - - SpoIIM HPHIIJEP_03749 224308.BSU23520 2.26e-104 301.0 COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,4HH78@91061|Bacilli,1ZCPG@1386|Bacillus 91061|Bacilli P Belongs to the Fur family fur GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03711 - - - - ko00000,ko03000 - - - FUR HPHIIJEP_03750 224308.BSU23519 2.73e-50 159.0 2E9B4@1|root,333IZ@2|Bacteria,1VHUQ@1239|Firmicutes,4HR2C@91061|Bacilli,1ZIY4@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4227) - - - - - - - - - - - - DUF4227 HPHIIJEP_03751 224308.BSU23510 2.26e-213 589.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus 91061|Bacilli L recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase HPHIIJEP_03752 224308.BSU23500 6.8e-294 801.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,1ZBG0@1386|Bacillus 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme HPHIIJEP_03753 224308.BSU23490 1.39e-190 529.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1ZBKZ@1386|Bacillus 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 HPHIIJEP_03754 224308.BSU23480 9.65e-271 742.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacF GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 HPHIIJEP_03755 1051501.AYTL01000030_gene2512 3e-76 228.0 COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus 91061|Bacilli T Belongs to the anti-sigma-factor antagonist family spoIIAA - - ko:K06378 - - - - ko00000 - - - STAS HPHIIJEP_03756 224308.BSU23460 1.37e-99 289.0 COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,4HGYN@91061|Bacilli,1ZFKS@1386|Bacillus 91061|Bacilli F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition spoIIAB GO:0000003,GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 ko:K06379 - - - - ko00000,ko01000 - - - HATPase_c_2 HPHIIJEP_03757 224308.BSU23450 1.18e-174 488.0 COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,4HC42@91061|Bacilli,1ZANZ@1386|Bacillus 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released sigF - - ko:K03091 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r3,Sigma70_r4 HPHIIJEP_03758 224308.BSU23440 1.15e-143 405.0 28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,4HFTI@91061|Bacilli,1ZBVY@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AA spoVAA - - ko:K06403 - - - - ko00000 - - - SporV_AA HPHIIJEP_03759 224308.BSU23430 5.43e-90 264.0 2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,4HIN3@91061|Bacilli,1ZGZY@1386|Bacillus 91061|Bacilli S Stage V sporulation protein AB spoVAB - - ko:K06404 - - - - ko00000 - - - SpoVAB HPHIIJEP_03760 224308.BSU23420 6.71e-102 295.0 2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,4HH0C@91061|Bacilli,1ZFW2@1386|Bacillus 91061|Bacilli S stage V sporulation protein AC spoVAC - - ko:K06405 - - - - ko00000 - - - SpoVAC_SpoVAEB HPHIIJEP_03761 224308.BSU23410 4.94e-245 672.0 COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,4H9W9@91061|Bacilli,1ZAW8@1386|Bacillus 91061|Bacilli I Stage V sporulation protein AD spoVAD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0031160,GO:0044464,GO:0071944 - ko:K06406 - - - - ko00000 - - - SpoVAD HPHIIJEP_03762 224308.BSU23402 2.15e-75 225.0 2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,4HIW4@91061|Bacilli,1ZG67@1386|Bacillus 91061|Bacilli S stage V sporulation protein spoVAEB - - ko:K06407 - - - - ko00000 - - - SpoVAC_SpoVAEB HPHIIJEP_03763 224308.BSU23401 1.85e-143 404.0 29419@1|root,2ZRG2@2|Bacteria,1V3UB@1239|Firmicutes,4HGP9@91061|Bacilli,1ZR7J@1386|Bacillus 91061|Bacilli S stage V sporulation protein - - - ko:K06407 - - - - ko00000 - - - SpoVAE HPHIIJEP_03764 224308.BSU23390 0.0 944.0 COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,4HBWN@91061|Bacilli,1ZB54@1386|Bacillus 91061|Bacilli EG Stage V sporulation protein AF spoVAF - - ko:K06408 - - - - ko00000 - - - GerA HPHIIJEP_03765 224308.BSU23380 0.0 880.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,1ZD43@1386|Bacillus 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC HPHIIJEP_03766 224308.BSU23370 8.93e-192 534.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,1ZD5H@1386|Bacillus 91061|Bacilli S Secreted protein ypuA - - - - - - - - - - - DUF1002 HPHIIJEP_03767 224308.BSU23360 1.23e-105 304.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4HHA1@91061|Bacilli,1ZFRG@1386|Bacillus 91061|Bacilli O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase HPHIIJEP_03769 224308.BSU23328 6.74e-30 107.0 COG3478@1|root,COG3478@2|Bacteria,1VEIV@1239|Firmicutes,4HNP6@91061|Bacilli,1ZJ32@1386|Bacillus 91061|Bacilli S nucleic-acid-binding protein containing a Zn-ribbon domain ypzJ - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 HPHIIJEP_03770 224308.BSU23310 9.28e-123 350.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli,1ZGNJ@1386|Bacillus 91061|Bacilli U Belongs to the peptidase S26 family lepB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 HPHIIJEP_03771 224308.BSU23300 5.98e-72 216.0 29RI8@1|root,30D34@2|Bacteria,1UAS0@1239|Firmicutes,4IM4U@91061|Bacilli,1ZJ5R@1386|Bacillus 91061|Bacilli - - ypuD - - - - - - - - - - - - HPHIIJEP_03772 224308.BSU23280 2.07e-260 713.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli,1ZBTJ@1386|Bacillus 91061|Bacilli H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 HPHIIJEP_03773 224308.BSU23270 2.5e-147 415.0 COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,1ZBB9@1386|Bacillus 91061|Bacilli H Riboflavin synthase ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08950,iYO844.BSU23270 Lum_binding HPHIIJEP_03774 224308.BSU23260 2.1e-290 792.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,1ZBF9@1386|Bacillus 91061|Bacilli H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribBA GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08945 DHBP_synthase,GTP_cyclohydro2 HPHIIJEP_03775 1051501.AYTL01000030_gene2493 8.41e-107 308.0 COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1ZFJ6@1386|Bacillus 91061|Bacilli H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08940 DMRL_synthase HPHIIJEP_03776 1051501.AYTL01000030_gene2492 1.12e-83 247.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,1ZHDK@1386|Bacillus 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 HPHIIJEP_03777 224308.BSU23230 1.19e-118 339.0 COG1547@1|root,COG1547@2|Bacteria,1V7AS@1239|Firmicutes,4HI8I@91061|Bacilli,1ZR7S@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 HPHIIJEP_03778 224308.BSU23220 3.82e-167 469.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,1ZDD6@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA HPHIIJEP_03779 224308.BSU23210 2e-135 384.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,1ZFNU@1386|Bacillus 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB HPHIIJEP_03780 224308.BSU23200 8.37e-126 358.0 29P42@1|root,30A29@2|Bacteria,1V423@1239|Firmicutes,4HH8N@91061|Bacilli,1ZG69@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3907) ypuI - - - - - - - - - - - DUF3907 HPHIIJEP_03781 224308.BSU23190 2.77e-271 743.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZBRQ@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S11 family dacB GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 HPHIIJEP_03782 224308.BSU23180 7.57e-135 382.0 COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,4HBTK@91061|Bacilli,1ZBSV@1386|Bacillus 91061|Bacilli S Spore maturation protein spmA - - ko:K06373 - - - - ko00000 - - - Gate HPHIIJEP_03783 224308.BSU23170 8.62e-114 327.0 COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,4HH1Y@91061|Bacilli,1ZFIY@1386|Bacillus 91061|Bacilli S Spore maturation protein spmB - - ko:K06374 - - - - ko00000 - - - Gate HPHIIJEP_03784 224308.BSU23160 4.45e-169 473.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,1ZBNQ@1386|Bacillus 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 HPHIIJEP_03785 224308.BSU23150 1.5e-128 365.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus 91061|Bacilli CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c resA GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - - - - - - - - - - AhpC-TSA HPHIIJEP_03786 224308.BSU23140 0.0 1087.0 COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes,4HAFD@91061|Bacilli,1ZBB3@1386|Bacillus 91061|Bacilli O COG1333 ResB protein required for cytochrome c biosynthesis resB - - ko:K07399 - - - - ko00000 - - - ResB HPHIIJEP_03787 224308.BSU23130 4.67e-279 763.0 COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,4HA2N@91061|Bacilli,1ZBH9@1386|Bacillus 91061|Bacilli O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' resC GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - - - - - - - - - - Cytochrom_C_asm HPHIIJEP_03788 224308.BSU23120 6.88e-171 477.0 COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,4HA7D@91061|Bacilli,1ZC0F@1386|Bacillus 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain resD - - ko:K07775 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C HPHIIJEP_03789 224308.BSU23110 0.0 1135.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus 91061|Bacilli T Histidine kinase resE - 2.7.13.3 ko:K07651 ko02020,map02020 M00458 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 HPHIIJEP_03790 224308.BSU23100 1.08e-133 379.0 COG1595@1|root,COG1595@2|Bacteria,1V4T2@1239|Firmicutes,4HFZ0@91061|Bacilli,1ZEC7@1386|Bacillus 91061|Bacilli K Belongs to the sigma-70 factor family. ECF subfamily sigX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 HPHIIJEP_03791 224308.BSU23090 1.34e-241 666.0 2E6XT@1|root,331H4@2|Bacteria,1VJ9Y@1239|Firmicutes,4HPEM@91061|Bacilli,1ZBUX@1386|Bacillus 91061|Bacilli - - rsiX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Germane HPHIIJEP_03792 224308.BSU23080 3.77e-171 479.0 COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,4HDMG@91061|Bacilli,1ZD9W@1386|Bacillus 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD GO:0003674,GO:0003824,GO:0003855,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I HPHIIJEP_03793 224308.BSU23070 0.0 1020.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZDB3@1386|Bacillus 91061|Bacilli E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU23070 2-Hacid_dh,2-Hacid_dh_C,ACT HPHIIJEP_03794 224308.BSU23050 1.78e-121 348.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,1ZG7K@1386|Bacillus 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt HPHIIJEP_03795 1051501.AYTL01000030_gene2472 8.35e-55 171.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,1ZHTS@1386|Bacillus 91061|Bacilli C Ferredoxin fer GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - ko:K05337 - - - - ko00000 - - - Fer4_13 HPHIIJEP_03796 224308.BSU23030 4.28e-253 694.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HFUR@91061|Bacilli,1ZDGR@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbB - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - HTH_40,RQC HPHIIJEP_03797 224308.BSU23020 0.0 983.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZB1X@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind HPHIIJEP_03798 224308.BSU23010 3.55e-128 365.0 COG1266@1|root,COG1266@2|Bacteria,1V4WK@1239|Firmicutes,4HHKM@91061|Bacilli,1ZEBP@1386|Bacillus 91061|Bacilli S metal-dependent membrane protease ypbD - - ko:K07052 - - - - ko00000 - - - Abi HPHIIJEP_03799 224308.BSU23000 6.75e-140 399.0 COG1388@1|root,COG1388@2|Bacteria,1V8A5@1239|Firmicutes,4HIV2@91061|Bacilli,1ZG8Q@1386|Bacillus 91061|Bacilli M Lysin motif ypbE - - - - - - - - - - - LysM HPHIIJEP_03800 224308.BSU22990 1.42e-106 306.0 2EENU@1|root,338GN@2|Bacteria,1VK1A@1239|Firmicutes,4HNX3@91061|Bacilli,1ZC57@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2663) ypbF - - - - - - - - - - - DUF2663 HPHIIJEP_03801 224308.BSU22980 4.33e-188 522.0 COG1408@1|root,COG1408@2|Bacteria,1V494@1239|Firmicutes,4HH1B@91061|Bacilli,1ZBFW@1386|Bacillus 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ypbG - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 HPHIIJEP_03802 224308.BSU22970 5.56e-136 385.0 COG4862@1|root,COG4862@2|Bacteria,1V1B7@1239|Firmicutes,4HBM5@91061|Bacilli,1ZF7G@1386|Bacillus 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC mecB GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K16511 - - - - ko00000 - - - MecA HPHIIJEP_03803 1051501.AYTL01000030_gene2464 1.42e-308 840.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,1ZAX4@1386|Bacillus 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gudB GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.4.1.2 ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N HPHIIJEP_03804 1051501.AYTL01000030_gene2463 2.15e-223 617.0 COG0492@1|root,COG0492@2|Bacteria,1TQGS@1239|Firmicutes,4HBIS@91061|Bacilli,1ZCBR@1386|Bacillus 91061|Bacilli O COG0492 Thioredoxin reductase ypdA - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_3 HPHIIJEP_03805 224308.BSU22940 1.76e-153 431.0 COG2339@1|root,COG2339@2|Bacteria,1UZGQ@1239|Firmicutes,4HCGD@91061|Bacilli,1ZBUQ@1386|Bacillus 91061|Bacilli S Involved in the degradation of specific anti-sigma factors prsW - - - - - - - - - - - PrsW-protease HPHIIJEP_03806 224308.BSU22930 1.99e-207 575.0 COG3409@1|root,COG3773@1|root,COG3409@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,4HA2V@91061|Bacilli,1ZB40@1386|Bacillus 91061|Bacilli M Spore cortex-lytic enzyme sleB GO:0005575,GO:0005623,GO:0042763,GO:0044464 3.5.1.28 ko:K01449 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Hydrolase_2,PG_binding_1 HPHIIJEP_03807 224308.BSU22920 0.0 879.0 COG2959@1|root,COG2959@2|Bacteria,1TT9K@1239|Firmicutes,4HBM9@91061|Bacilli,1ZB4M@1386|Bacillus 91061|Bacilli H sporulation protein ypeB - - ko:K06313 - - - - ko00000 - - - PepSY,YPEB HPHIIJEP_03808 224308.BSU22910 8.95e-142 401.0 COG5581@1|root,COG5581@2|Bacteria,1V31U@1239|Firmicutes,4HGFE@91061|Bacilli,1ZCCG@1386|Bacillus 91061|Bacilli M Flagellar protein YcgR ypfA - - - - - - - - - - - PilZ,YcgR_2 HPHIIJEP_03809 224308.BSU22900 2.48e-32 112.0 29NTG@1|root,309RK@2|Bacteria,1U5JI@1239|Firmicutes,4IFAC@91061|Bacilli,1ZK0C@1386|Bacillus 91061|Bacilli S Family of unknown function (DUF5359) - - - - - - - - - - - - DUF5359 HPHIIJEP_03810 224308.BSU22890 1.94e-144 409.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin HPHIIJEP_03811 224308.BSU22880 2.23e-261 717.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,1ZARR@1386|Bacillus 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 HPHIIJEP_03812 224308.BSU22870 9.39e-235 647.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,1ZCXC@1386|Bacillus 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh HPHIIJEP_03813 1196324.A374_03349 2.29e-11 58.5 2EHPS@1|root,33BFI@2|Bacteria,1VM1E@1239|Firmicutes,4HS3S@91061|Bacilli 91061|Bacilli S YpzI-like protein - - - - - - - - - - - - YpzI HPHIIJEP_03814 224308.BSU22860 4.52e-133 378.0 2C369@1|root,32TN5@2|Bacteria,1VDHE@1239|Firmicutes,4HN2A@91061|Bacilli 91061|Bacilli - - yphA - - - - - - - - - - - - HPHIIJEP_03815 224308.BSU22850 4.35e-207 573.0 28IBV@1|root,2Z8EA@2|Bacteria,1TPCJ@1239|Firmicutes,4HB3C@91061|Bacilli,1ZBT4@1386|Bacillus 91061|Bacilli S YIEGIA protein yphB - - ko:K05739 - - - - ko00000 - - - YIEGIA HPHIIJEP_03816 224308.BSU22849 5.91e-38 127.0 2E5GX@1|root,3308G@2|Bacteria,1VGKE@1239|Firmicutes,4HPSE@91061|Bacilli,1ZIU7@1386|Bacillus 91061|Bacilli - - ypzH - - - - - - - - - - - - HPHIIJEP_03817 224308.BSU22840 1.72e-315 859.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 HPHIIJEP_03818 224308.BSU22830 6.32e-231 637.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,1ZCHQ@1386|Bacillus 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N HPHIIJEP_03819 1274524.BSONL12_01907 7.09e-27 99.4 2EJSH@1|root,33DH6@2|Bacteria,1VMUI@1239|Firmicutes,4HS5M@91061|Bacilli,1ZJ2B@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2768) yphE - - - - - - - - - - - DUF2768 HPHIIJEP_03820 224308.BSU22810 4.31e-176 490.0 28J08@1|root,2Z8XG@2|Bacteria,1V177@1239|Firmicutes,4HCWC@91061|Bacilli,1ZCRV@1386|Bacillus 91061|Bacilli - - yphF - - - - - - - - - - - DUF3939 HPHIIJEP_03821 224308.BSU22800 0.0 964.0 COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,4HBH1@91061|Bacilli,1ZBNH@1386|Bacillus 91061|Bacilli S ATPase. Has a role at an early stage in the morphogenesis of the spore coat spoIVA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009653,GO:0009847,GO:0009987,GO:0010927,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030154,GO:0030203,GO:0030312,GO:0030435,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032989,GO:0034622,GO:0035639,GO:0036094,GO:0042244,GO:0042546,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043170,GO:0043591,GO:0043595,GO:0043933,GO:0043934,GO:0044085,GO:0044426,GO:0044462,GO:0044464,GO:0045229,GO:0048646,GO:0048856,GO:0048869,GO:0051258,GO:0051259,GO:0065003,GO:0070499,GO:0070590,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 - ko:K06398 - - - - ko00000 - - - Spore_IV_A HPHIIJEP_03822 1051501.AYTL01000030_gene2445 1.07e-57 179.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hbs GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding HPHIIJEP_03823 224308.BSU22780 4.41e-131 372.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus 91061|Bacilli H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI HPHIIJEP_03824 224308.BSU22770 5.13e-46 148.0 2E4ES@1|root,32Z9Y@2|Bacteria,1VF84@1239|Firmicutes,4HNYS@91061|Bacilli,1ZHX6@1386|Bacillus 91061|Bacilli K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan mtrB - - ko:K06285 - - - - ko00000,ko03000 - - - TrpBP HPHIIJEP_03825 224308.BSU22760 7.17e-177 493.0 COG0142@1|root,COG0142@2|Bacteria,1V1TG@1239|Firmicutes,4HFY5@91061|Bacilli,1ZQJT@1386|Bacillus 91061|Bacilli H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 hepS GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - HEPPP_synt_1 HPHIIJEP_03826 224308.BSU22750 1.34e-169 473.0 COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,1ZB6U@1386|Bacillus 91061|Bacilli H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran HPHIIJEP_03827 224308.BSU22740 4.09e-249 684.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,1ZAZ7@1386|Bacillus 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt HPHIIJEP_03828 224308.BSU22730 2.17e-104 301.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,1ZFJ7@1386|Bacillus 91061|Bacilli F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK HPHIIJEP_03829 224308.BSU22720 3.03e-182 507.0 COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,4HAS1@91061|Bacilli,1ZCKU@1386|Bacillus 91061|Bacilli NT COG1352 Methylase of chemotaxis methyl-accepting proteins cheR - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N HPHIIJEP_03830 224308.BSU22710 1.44e-277 759.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli,1ZB2N@1386|Bacillus 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt HPHIIJEP_03831 224308.BSU22700 2.23e-260 713.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli,1ZC9C@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase HPHIIJEP_03832 224308.BSU22690 9.82e-84 247.0 COG4401@1|root,COG4401@2|Bacteria,1VAID@1239|Firmicutes,4HKTN@91061|Bacilli,1ZH0S@1386|Bacillus 91061|Bacilli E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 HPHIIJEP_03833 224308.BSU22680 0.0 1008.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,1ZARE@1386|Bacillus 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind HPHIIJEP_03834 224308.BSU22670 5e-229 632.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,1ZBZ1@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 HPHIIJEP_03835 1051501.AYTL01000030_gene2432 2.42e-144 410.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,1ZD63@1386|Bacillus 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS HPHIIJEP_03836 224308.BSU22650 2.14e-148 418.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HJ7Y@91061|Bacilli,1ZGH8@1386|Bacillus 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI HPHIIJEP_03837 224308.BSU22640 2.57e-292 797.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,1ZCBT@1386|Bacillus 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP HPHIIJEP_03838 224308.BSU22630 3.66e-184 513.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,1ZC5U@1386|Bacillus 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA HPHIIJEP_03839 224308.BSU22620 1.24e-256 704.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,1ZBYJ@1386|Bacillus 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_03840 224308.BSU22610 1.21e-264 725.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli,1ZBVZ@1386|Bacillus 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH HPHIIJEP_03841 224308.BSU22600 4.03e-301 822.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,1ZBP0@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase HPHIIJEP_03842 224308.BSU22590 8.74e-298 813.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,1ZAZM@1386|Bacillus 91061|Bacilli S COG0457 FOG TPR repeat ypiA - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_7,TPR_8 HPHIIJEP_03843 1051501.AYTL01000030_gene2424 1.83e-129 367.0 COG5582@1|root,COG5582@2|Bacteria,1V5KV@1239|Firmicutes,4HEE0@91061|Bacilli,1ZB4J@1386|Bacillus 91061|Bacilli S Belongs to the UPF0302 family ypiB - - - - - - - - - - - IDEAL,UPF0302 HPHIIJEP_03844 224308.BSU22570 5.55e-100 290.0 2CSPZ@1|root,32SRK@2|Bacteria,1VBS0@1239|Firmicutes,4HKXQ@91061|Bacilli,1ZI4R@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2487) ypiF - - - - - - - - - - - DUF2487 HPHIIJEP_03845 224308.BSU22560 3.35e-126 358.0 COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,1ZFNX@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase qcrA - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CytB6-F_Fe-S,Rieske HPHIIJEP_03846 1051501.AYTL01000030_gene2421 8.76e-166 462.0 COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,4H9XV@91061|Bacilli,1ZB3U@1386|Bacillus 91061|Bacilli C COG1290 Cytochrome b subunit of the bc complex qcrB - - ko:K03887 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrome_B HPHIIJEP_03847 224308.BSU22540 3.31e-190 527.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1TRS8@1239|Firmicutes,4H9XH@91061|Bacilli,1ZCZW@1386|Bacillus 91061|Bacilli C Menaquinol-cytochrome c reductase cytochrome b c subunit qcrC - - ko:K03888 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002 - - - Cytochrom_B_C,Cytochrome_CBB3 HPHIIJEP_03848 1051501.AYTL01000030_gene2419 1.15e-125 359.0 COG4347@1|root,COG4347@2|Bacteria,1V1NI@1239|Firmicutes,4HFTW@91061|Bacilli,1ZFJF@1386|Bacillus 91061|Bacilli S membrane ypjA - - - - - - - - - - - DUF1405 HPHIIJEP_03849 224308.BSU22520 2.79e-182 508.0 28RMR@1|root,2ZE0H@2|Bacteria,1V1HS@1239|Firmicutes,4HFRG@91061|Bacilli,1ZANV@1386|Bacillus 91061|Bacilli S sporulation protein ypjB - - - - - - - - - - - Spore_YpjB HPHIIJEP_03850 224308.BSU22510 3.7e-200 555.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,1ZBUC@1386|Bacillus 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2179) ypjC - - - - - - - - - - - DUF2179,YitT_membrane HPHIIJEP_03851 224308.BSU22500 1.01e-73 221.0 COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,4HISK@91061|Bacilli,1ZH1U@1386|Bacillus 91061|Bacilli S Nucleotide pyrophosphohydrolase ypjD - - - - - - - - - - - MazG HPHIIJEP_03852 224308.BSU22490 2.4e-189 526.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,1ZAWD@1386|Bacillus 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N HPHIIJEP_03853 224308.BSU22480 1.03e-92 271.0 COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,4HH64@91061|Bacilli,1ZGAF@1386|Bacillus 91061|Bacilli G methylglyoxal synthase mgsA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS HPHIIJEP_03854 224308.BSU22470 1.89e-166 465.0 COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1ZAZI@1386|Bacillus 91061|Bacilli S proteins, LmbE homologs bshB1 - - ko:K01463 - - - - ko00000,ko01000 - - - PIG-L HPHIIJEP_03855 224308.BSU22460 4.94e-267 731.0 COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,4HA43@91061|Bacilli,1ZASJ@1386|Bacillus 91061|Bacilli M N-acetyl-alpha-D-glucosaminyl L-malate synthase bshA GO:0003674,GO:0003824,GO:0016740,GO:0016757 - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 HPHIIJEP_03856 224308.BSU22450 2.6e-279 764.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,1ZC20@1386|Bacillus 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 HPHIIJEP_03857 224308.BSU22440 4.87e-234 644.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,1ZBI9@1386|Bacillus 91061|Bacilli K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 HPHIIJEP_03858 224308.BSU22430 4.85e-194 538.0 COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,1ZAWV@1386|Bacillus 91061|Bacilli H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22430 Pantoate_transf HPHIIJEP_03859 224308.BSU22420 3.69e-198 550.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,1ZAV5@1386|Bacillus 91061|Bacilli H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase HPHIIJEP_03860 224308.BSU22410 4.16e-85 251.0 COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,4HIV1@91061|Bacilli,1ZG9V@1386|Bacillus 91061|Bacilli H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox HPHIIJEP_03861 224308.BSU22400 0.0 1829.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,1ZAWI@1386|Bacillus 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII HPHIIJEP_03862 1051501.AYTL01000030_gene2405 1.52e-32 112.0 2E85E@1|root,332IZ@2|Bacteria,1VHMN@1239|Firmicutes,4HPYR@91061|Bacilli,1ZIUT@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF4264) ypmA - - - - - - - - - - - DUF4264 HPHIIJEP_03863 224308.BSU22380 2.66e-102 297.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,1ZFVJ@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmB - - - - - - - - - - - PepSY HPHIIJEP_03864 224308.BSU22370 4.37e-285 778.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,1ZCMB@1386|Bacillus 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 HPHIIJEP_03865 224308.BSU22360 0.0 871.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,1ZC51@1386|Bacillus 91061|Bacilli J asparaginyl-tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon HPHIIJEP_03866 224308.BSU22350 6.62e-165 461.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,1ZC34@1386|Bacillus 91061|Bacilli L DNA replication protein DnaD dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 HPHIIJEP_03867 224308.BSU22340 3.57e-158 443.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,1ZBJE@1386|Bacillus 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD HPHIIJEP_03868 224308.BSU22330 4.59e-118 337.0 2EGVD@1|root,33AMM@2|Bacteria,1VKVK@1239|Firmicutes,4HRYS@91061|Bacilli,1ZITC@1386|Bacillus 91061|Bacilli - - ypoC - - - - - - - - - - - - HPHIIJEP_03869 224308.BSU22320 0.0 1468.0 COG0744@1|root,COG4499@1|root,COG0744@2|Bacteria,COG4499@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,1ZAXY@1386|Bacillus 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 HPHIIJEP_03870 224308.BSU22310 3.2e-150 422.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,1ZCV9@1386|Bacillus 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU HPHIIJEP_03871 224308.BSU22300 9.85e-236 647.0 28MSG@1|root,2ZB0U@2|Bacteria,1TT1H@1239|Firmicutes,4HBNQ@91061|Bacilli,1ZCHW@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2515) yppC - - - - - - - - - - - DUF2515 HPHIIJEP_03874 545693.BMQ_1406 1.42e-10 61.6 2C8E7@1|root,32RKZ@2|Bacteria,1VIES@1239|Firmicutes,4HKFC@91061|Bacilli,1ZITF@1386|Bacillus 91061|Bacilli S Bacterial domain of unknown function (DUF1798) yppE - - - - - - - - - - - DUF1798 HPHIIJEP_03875 935836.JAEL01000006_gene2795 9.21e-11 58.5 2ETMY@1|root,33M5Q@2|Bacteria,1VPZB@1239|Firmicutes,4HR2S@91061|Bacilli,1ZKDZ@1386|Bacillus 91061|Bacilli S YppF-like protein - - - - - - - - - - - - YppF HPHIIJEP_03876 224308.BSU22250 8.72e-68 207.0 29NR8@1|root,309P6@2|Bacteria,1U5F9@1239|Firmicutes,4IF6W@91061|Bacilli,1ZJ7A@1386|Bacillus 91061|Bacilli S YppG-like protein yppG - - - - - - - - - - - YppG HPHIIJEP_03877 224308.BSU22240 1.76e-94 275.0 COG0071@1|root,COG0071@2|Bacteria 2|Bacteria O Belongs to the small heat shock protein (HSP20) family hspX GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - ko:K06335,ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HPHIIJEP_03878 224308.BSU22230 6.45e-111 319.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,1ZG91@1386|Bacillus 91061|Bacilli G COG2190 Phosphotransferase system IIA components ypqE - - ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1 - - PTS_EIIA_1 HPHIIJEP_03879 224308.BSU22220 0.0 1491.0 COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,4H9T2@91061|Bacilli,1ZDM5@1386|Bacillus 91061|Bacilli L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster yprA GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C HPHIIJEP_03880 224308.BSU22210 5.68e-298 813.0 COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,1ZAZQ@1386|Bacillus 91061|Bacilli L RNase_H superfamily yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 HPHIIJEP_03881 224308.BSU22190 2.4e-128 364.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,1ZFYS@1386|Bacillus 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 HPHIIJEP_03882 224308.BSU22180 2.97e-60 186.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HKUX@91061|Bacilli,1ZH10@1386|Bacillus 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA HPHIIJEP_03883 224308.BSU22170 1.16e-285 779.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,1ZBJB@1386|Bacillus 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 HPHIIJEP_03885 224308.BSU22150 0.0 1268.0 COG1199@1|root,COG1199@2|Bacteria,1TRNV@1239|Firmicutes,4HBYD@91061|Bacilli,1ZARY@1386|Bacillus 91061|Bacilli KL COG1199 Rad3-related DNA helicases ypvA - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - Helicase_C_2 HPHIIJEP_03886 224308.BSU22140 4.63e-176 491.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,1ZC4X@1386|Bacillus 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) kduD - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 HPHIIJEP_03887 224308.BSU22130 2.96e-203 561.0 COG3717@1|root,COG3717@2|Bacteria,1VSXE@1239|Firmicutes,4HU2K@91061|Bacilli,1ZQMN@1386|Bacillus 91061|Bacilli G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate kduI - 5.3.1.17 ko:K01815 ko00040,map00040 - R04383 RC00541 ko00000,ko00001,ko01000 - - - KduI HPHIIJEP_03888 224308.BSU22120 7.8e-238 654.0 COG1609@1|root,COG1609@2|Bacteria,1TQSY@1239|Firmicutes,4HAJI@91061|Bacilli,1ZEA9@1386|Bacillus 91061|Bacilli K transcriptional kdgR - - ko:K02525 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 HPHIIJEP_03889 224308.BSU22110 2.83e-237 652.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HBH6@91061|Bacilli,1ZC46@1386|Bacillus 91061|Bacilli G COG0524 Sugar kinases, ribokinase family kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB HPHIIJEP_03890 224308.BSU22100 1.2e-131 374.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,1ZEB4@1386|Bacillus 91061|Bacilli G 2-dehydro-3-deoxy-phosphogluconate aldolase kdgA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase HPHIIJEP_03891 224308.BSU22090 4.09e-224 619.0 28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,4HE88@91061|Bacilli,1ZDHF@1386|Bacillus 91061|Bacilli P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system kdgT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02526 - - - - ko00000,ko02000 2.A.10.1 - - KdgT HPHIIJEP_03892 224308.BSU22080 0.0 1009.0 COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,1ZB3X@1386|Bacillus 91061|Bacilli E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues ypwA GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 ko:K01299 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M32 HPHIIJEP_03893 224308.BSU22070 9.13e-126 359.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,1ZFTS@1386|Bacillus 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran HPHIIJEP_03894 224308.BSU22060 4.98e-291 797.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,1ZAUK@1386|Bacillus 91061|Bacilli F xanthine pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169,ko:K16170 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1,2.A.40.3.2 - iSB619.SA_RS02140 Xan_ur_permease HPHIIJEP_03895 224308.BSU22050 2.63e-265 726.0 COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,1ZC8W@1386|Bacillus 91061|Bacilli Q Naringenin-chalcone synthase bcsA - - ko:K16167 - - - - ko00000,ko01008 - - - Chal_sti_synt_C,Chal_sti_synt_N HPHIIJEP_03896 224308.BSU22040 3.33e-113 325.0 COG1755@1|root,COG1755@2|Bacteria,1V6IY@1239|Firmicutes,4HIFN@91061|Bacilli,1ZGT0@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypbQ - - ko:K16168 - - - - ko00000,ko01008 - - - ICMT HPHIIJEP_03897 224308.BSU22030 0.0 2218.0 COG0699@1|root,COG0699@2|Bacteria,1TR0Q@1239|Firmicutes,4HBAC@91061|Bacilli,1ZAXM@1386|Bacillus 91061|Bacilli S Dynamin family ypbR GO:0000910,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022402,GO:0022607,GO:0031224,GO:0032506,GO:0044085,GO:0044425,GO:0051301,GO:0071840,GO:0090529 - - - - - - - - - - Dynamin_N HPHIIJEP_03898 224308.BSU22020 6.77e-51 161.0 2E0UC@1|root,32WBV@2|Bacteria,1VDJ2@1239|Firmicutes,4HKXT@91061|Bacilli,1ZJ5C@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2533) ypbS - - - - - - - - - - - DUF2533 HPHIIJEP_03899 224308.BSU22010 4.57e-213 588.0 COG0258@1|root,COG0258@2|Bacteria,1TQ05@1239|Firmicutes,4H9UW@91061|Bacilli,1ZB2Z@1386|Bacillus 91061|Bacilli L 5'3' exonuclease ypcP - - - - - - - - - - - 5_3_exonuc,5_3_exonuc_N HPHIIJEP_03900 315750.BPUM_1936 5.23e-05 42.4 29S9K@1|root,30DE3@2|Bacteria,1UB6V@1239|Firmicutes,4IMJJ@91061|Bacilli,1ZKAQ@1386|Bacillus 91061|Bacilli - - - - - ko:K06429 - - - - ko00000 - - - - HPHIIJEP_03901 224308.BSU21990 4.25e-85 251.0 COG0328@1|root,COG0328@2|Bacteria,1VE23@1239|Firmicutes,4HKXV@91061|Bacilli,1ZQJB@1386|Bacillus 91061|Bacilli L Ribonuclease rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 HPHIIJEP_03902 224308.BSU21980 3.27e-136 387.0 COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,4HB9T@91061|Bacilli,1ZEKB@1386|Bacillus 91061|Bacilli S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage ypdP - - ko:K09125 - - - - ko00000 - - - Vut_1 HPHIIJEP_03903 224308.BSU21970 1.1e-160 450.0 COG0328@1|root,COG0328@2|Bacteria,1V3K2@1239|Firmicutes,4HE8H@91061|Bacilli,1ZDMZ@1386|Bacillus 91061|Bacilli L COG0328 Ribonuclease HI ypeP - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 HPHIIJEP_03904 224308.BSU21960 1.54e-37 125.0 2E6UK@1|root,331EA@2|Bacteria,1VF2M@1239|Firmicutes,4HPQ1@91061|Bacilli,1ZKC4@1386|Bacillus 91061|Bacilli S Zinc-finger ypeQ - - - - - - - - - - - zf-C2HCIx2C HPHIIJEP_03905 1051501.AYTL01000030_gene2361 1.05e-40 135.0 29S2J@1|root,30D72@2|Bacteria,1UAXW@1239|Firmicutes,4IMAQ@91061|Bacilli,1ZJNM@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2564) - - - - - - - - - - - - DUF2564 HPHIIJEP_03906 1274524.BSONL12_01472 1.17e-22 88.2 29S43@1|root,30D8J@2|Bacteria,1UAZQ@1239|Firmicutes,4IMCJ@91061|Bacilli,1ZJT7@1386|Bacillus 91061|Bacilli - - degR - - - - - - - - - - - - HPHIIJEP_03907 1051501.AYTL01000030_gene2359 5.12e-42 137.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,1ZHTU@1386|Bacillus 91061|Bacilli K Cold-shock protein cspD - - ko:K03704 - - - - ko00000,ko03000 - - - CSD HPHIIJEP_03908 224308.BSU21920 1.28e-276 756.0 COG0707@1|root,COG0707@2|Bacteria,1TR07@1239|Firmicutes,4HBKJ@91061|Bacilli,1ZQUQ@1386|Bacillus 91061|Bacilli M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA) ugtP GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228 2.4.1.315 ko:K03429 ko00561,ko01100,map00561,map01100 - R02689,R04377 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT28 - Glyco_tran_28_C,Glycos_transf_1,MGDG_synth HPHIIJEP_03909 224308.BSU21910 1.23e-224 618.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,1ZCTU@1386|Bacillus 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS HPHIIJEP_03910 224308.BSU21900 3.13e-114 327.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,1ZGBN@1386|Bacillus 91061|Bacilli O Belongs to the glutathione peroxidase family bsaA - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx HPHIIJEP_03911 224308.BSU21890 1.2e-140 397.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,1ZB0E@1386|Bacillus 91061|Bacilli S phosphohydrolase yagB - - ko:K06950 - - - - ko00000 - - - HD HPHIIJEP_03912 224308.BSU21880 2.32e-203 570.0 COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli,1ZB7F@1386|Bacillus 91061|Bacilli C COG0694 Thioredoxin-like proteins and domains ypgR - - - - - - - - - - - HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact HPHIIJEP_03913 224308.BSU21870 0.0 1108.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,1ZASK@1386|Bacillus 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD HPHIIJEP_03914 224308.BSU21860 9.69e-99 286.0 28NYH@1|root,2ZBVN@2|Bacteria,1V1T3@1239|Firmicutes,4HHZS@91061|Bacilli,1ZGM0@1386|Bacillus 91061|Bacilli S Belongs to the UPF0403 family yphP - - - - - - - - - - - Disulph_isomer HPHIIJEP_03915 224308.BSU21850 1.02e-185 516.0 COG2136@1|root,COG2521@1|root,COG2136@2|Bacteria,COG2521@2|Bacteria,1UIYD@1239|Firmicutes,4ISX3@91061|Bacilli,1ZS7M@1386|Bacillus 91061|Bacilli AJ Putative SAM-dependent methyltransferase ypiP - - - - - - - - - - - SAM_MT HPHIIJEP_03916 224308.BSU21840 3.47e-148 416.0 2C2Z4@1|root,2ZV7K@2|Bacteria,1V3JN@1239|Firmicutes,4HHVS@91061|Bacilli,1ZGAN@1386|Bacillus 91061|Bacilli S YpjP-like protein ypjP - - - - - - - - - - - YpjP HPHIIJEP_03917 1051501.AYTL01000030_gene2349 8.91e-121 345.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,1ZCY9@1386|Bacillus 91061|Bacilli I COG1267 Phosphatidylglycerophosphatase A and related proteins ltrC - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA HPHIIJEP_03918 224308.BSU21810 7.88e-121 344.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,1ZG71@1386|Bacillus 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis dfrA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 HPHIIJEP_03919 224308.BSU21800 1.11e-141 400.0 COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,4HD2E@91061|Bacilli,1ZEYG@1386|Bacillus 91061|Bacilli I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family ypkP - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase HPHIIJEP_03920 224308.BSU21790 8.03e-143 404.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,1ZBJJ@1386|Bacillus 91061|Bacilli S protein, Hemolysin III yplQ - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII HPHIIJEP_03921 224308.BSU21780 5.7e-236 649.0 COG1221@1|root,COG1221@2|Bacteria,1VSHE@1239|Firmicutes,4ISX2@91061|Bacilli,1ZEVI@1386|Bacillus 91061|Bacilli K Transcriptional regulator yplP - - - - - - - - - - - HTH_12,Sigma54_activ_2,Sigma54_activat HPHIIJEP_03922 224308.BSU21770 3.64e-310 844.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,1ZBM0@1386|Bacillus 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C HPHIIJEP_03923 224308.BSU21760 2.12e-53 167.0 2E2C2@1|root,32XH4@2|Bacteria,1VDJY@1239|Firmicutes,4HMBA@91061|Bacilli,1ZIXP@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2535) ypmP - - - - - - - - - - - DUF2535 HPHIIJEP_03924 224308.BSU21750 2.55e-136 385.0 COG1999@1|root,COG1999@2|Bacteria,1V03J@1239|Firmicutes,4HET3@91061|Bacilli,1ZFJQ@1386|Bacillus 91061|Bacilli S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems ypmQ - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC HPHIIJEP_03925 224308.BSU21740 1.28e-178 498.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,1ZRET@1386|Bacillus 91061|Bacilli E GDSL-like Lipase/Acylhydrolase ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 - - - - - - - - - - Lipase_GDSL_2 HPHIIJEP_03926 224308.BSU21730 1.13e-127 363.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,1ZF26@1386|Bacillus 91061|Bacilli S protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 HPHIIJEP_03927 224308.BSU21720 2.13e-40 133.0 29RUY@1|root,30CYZ@2|Bacteria,1UAK7@1239|Firmicutes,4IKYV@91061|Bacilli,1ZIEX@1386|Bacillus 91061|Bacilli S Uncharacterized ympT ypmT - - - - - - - - - - - ypmT HPHIIJEP_03928 224308.BSU21710 7.03e-290 795.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,1ZEAW@1386|Bacillus 91061|Bacilli V MATE efflux family protein mepA - - - - - - - - - - - MatE HPHIIJEP_03929 224308.BSU21700 4.14e-94 275.0 COG1846@1|root,COG1846@2|Bacteria,1V3P7@1239|Firmicutes,4HPNY@91061|Bacilli,1ZHZC@1386|Bacillus 91061|Bacilli K transcriptional ypoP GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - MarR HPHIIJEP_03930 224308.BSU21690 8.09e-132 373.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli,1ZCC5@1386|Bacillus 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrB - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR HPHIIJEP_03931 224308.BSU21680 2.9e-102 295.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,1ZFQG@1386|Bacillus 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR HPHIIJEP_03932 315750.BPUM_1899 1.66e-157 451.0 COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,4HAER@91061|Bacilli,1ZB9K@1386|Bacillus 91061|Bacilli GM Polysaccharide biosynthesis protein - - - ko:K19421 - - - - ko00000 - - - CoA_binding_3,Polysacc_synt_2 HPHIIJEP_03933 224308.BSU19800 1.9e-278 761.0 COG4247@1|root,COG4247@2|Bacteria,1VRJS@1239|Firmicutes,4HV5E@91061|Bacilli,1ZM0Y@1386|Bacillus 91061|Bacilli I Myo-inositol-hexaphosphate 3-phosphohydrolase phy - 3.1.3.8 ko:K01083 ko00562,map00562 - R03371 RC00078 ko00000,ko00001,ko01000 - - - Cu_amine_oxidN1,Phytase HPHIIJEP_03934 224308.BSU19790 9.37e-228 627.0 COG4641@1|root,COG4641@2|Bacteria,1TQNB@1239|Firmicutes,4HBH5@91061|Bacilli,1ZF3Y@1386|Bacillus 91061|Bacilli S Spore maturation protein cgeB - - ko:K06320 - - - - ko00000 - - - DUF3880,Glyco_trans_1_2 HPHIIJEP_03935 224308.BSU19780 3.1e-83 246.0 29RIJ@1|root,30CMI@2|Bacteria,1UA3F@1239|Firmicutes,4IKD5@91061|Bacilli,1ZGHQ@1386|Bacillus 91061|Bacilli - - cgeA - - ko:K06319 - - - - ko00000 - - - - HPHIIJEP_03936 224308.BSU19770 1.06e-59 184.0 29RRN@1|root,30CVA@2|Bacteria,1UAEY@1239|Firmicutes,4IKT8@91061|Bacilli,1ZHGH@1386|Bacillus 91061|Bacilli - - cgeC - - ko:K06321 - - - - ko00000 - - - - HPHIIJEP_03937 224308.BSU19760 0.0 872.0 COG0463@1|root,COG0463@2|Bacteria,1VT8J@1239|Firmicutes,4HU2T@91061|Bacilli,1ZBH8@1386|Bacillus 91061|Bacilli M maturation of the outermost layer of the spore cgeD - - ko:K06322 - - - - ko00000 - - - Glycos_transf_2 HPHIIJEP_03938 224308.BSU19750 5.43e-182 506.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase yiiD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - ko:K06323 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10,YiiD_C HPHIIJEP_03941 224308.BSU19740 9.36e-317 863.0 COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4HD8E@91061|Bacilli,1ZAWS@1386|Bacillus 91061|Bacilli H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family yodT - - - - - - - - - - - Aminotran_3 HPHIIJEP_03942 224308.BSU19730 1.97e-160 449.0 COG1788@1|root,COG1788@2|Bacteria,1TSZT@1239|Firmicutes,4HDJG@91061|Bacilli,1ZQEH@1386|Bacillus 91061|Bacilli I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit atoD - 2.8.3.8,2.8.3.9 ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans HPHIIJEP_03943 224308.BSU19720 9.44e-153 429.0 COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,4HBFR@91061|Bacilli,1ZB4Q@1386|Bacillus 91061|Bacilli I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit atoA - 2.8.3.8,2.8.3.9 ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 - R01179,R01359,R01365,R07832 RC00012,RC00014 ko00000,ko00001,ko01000 - - - CoA_trans HPHIIJEP_03944 224308.BSU19710 0.0 892.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase yodQ - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 HPHIIJEP_03945 224308.BSU19700 5.27e-197 546.0 COG0454@1|root,COG0456@2|Bacteria,1V4AF@1239|Firmicutes,4HD36@91061|Bacilli,1ZCVH@1386|Bacillus 91061|Bacilli K Acetyltransferase (GNAT) family yodP - 2.3.1.264 ko:K21935 - - R11701 - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 HPHIIJEP_03946 224308.BSU19690 0.0 957.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,4HE2P@91061|Bacilli,1ZBET@1386|Bacillus 91061|Bacilli E lysine 2,3-aminomutase kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM HPHIIJEP_03947 224308.BSU19689 3.44e-63 192.0 2FGYP@1|root,348TV@2|Bacteria,1VZPM@1239|Firmicutes,4HYBM@91061|Bacilli,1ZHW2@1386|Bacillus 91061|Bacilli S YokU-like protein, putative antitoxin yokU - - - - - - - - - - - YokU HPHIIJEP_03948 224308.BSU19680 7.3e-50 157.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,1ZJ7C@1386|Bacillus 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like HPHIIJEP_03949 224308.BSU19670 7.44e-159 445.0 2ESB9@1|root,33JW0@2|Bacteria,1VMVV@1239|Firmicutes,4HSTZ@91061|Bacilli,1ZD8X@1386|Bacillus 91061|Bacilli - - yodN - - - - - - - - - - - - HPHIIJEP_03951 224308.BSU19660 5.18e-34 116.0 28VRR@1|root,2ZHTJ@2|Bacteria,1W6RM@1239|Firmicutes,4IFAF@91061|Bacilli,1ZITN@1386|Bacillus 91061|Bacilli S YozD-like protein yozD - - - - - - - - - - - YozD HPHIIJEP_03952 224308.BSU19650 4.02e-138 391.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,1ZJJP@1386|Bacillus 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 HPHIIJEP_03953 224308.BSU19640 1.17e-71 215.0 2FBM7@1|root,343SB@2|Bacteria,1VAAQ@1239|Firmicutes,4HYUG@91061|Bacilli,1ZIA3@1386|Bacillus 91061|Bacilli S YodL-like yodL - - - - - - - - - - - YodL HPHIIJEP_03954 1382315.JPOI01000001_gene2627 2.08e-12 61.2 2EKRV@1|root,33EFM@2|Bacteria,1VQ20@1239|Firmicutes,4HSEI@91061|Bacilli,1WGZZ@129337|Geobacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03955 224308.BSU19630 1.68e-163 457.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,1ZCBV@1386|Bacillus 91061|Bacilli F Purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 HPHIIJEP_03956 224308.BSU19620 3.82e-189 526.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli,1ZCAG@1386|Bacillus 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY HPHIIJEP_03957 224308.BSU19610 4.86e-41 136.0 2DPDU@1|root,331PB@2|Bacteria,1VFH2@1239|Firmicutes,4HQIZ@91061|Bacilli,1ZJAM@1386|Bacillus 91061|Bacilli - - yodI - - - - - - - - - - - - HPHIIJEP_03958 224308.BSU19600 3.03e-166 464.0 COG0500@1|root,COG2226@2|Bacteria,1V4RW@1239|Firmicutes,4HIF0@91061|Bacilli,1ZE3P@1386|Bacillus 91061|Bacilli Q Methyltransferase yodH GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 HPHIIJEP_03959 224308.BSU19590 0.0 876.0 COG0793@1|root,COG3409@1|root,COG0793@2|Bacteria,COG3409@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus 91061|Bacilli M Belongs to the peptidase S41A family ctpA GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 HPHIIJEP_03960 224308.BSU19580 0.0 927.0 COG0591@1|root,COG0591@2|Bacteria,1TRYH@1239|Firmicutes,4HE2W@91061|Bacilli,1ZCBN@1386|Bacillus 91061|Bacilli E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yodF - - ko:K03307 - - - - ko00000 2.A.21 - - SSF HPHIIJEP_03961 224308.BSU19579 2.36e-38 128.0 2EFSS@1|root,339IS@2|Bacteria,1VMRC@1239|Firmicutes,4HR88@91061|Bacilli,1ZI2T@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF3311) - - - - - - - - - - - - DUF3311 HPHIIJEP_03962 224308.BSU19570 4.8e-223 614.0 COG0346@1|root,COG0346@2|Bacteria,1TQCN@1239|Firmicutes,4HAMC@91061|Bacilli,1ZAQY@1386|Bacillus 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases yodE - - ko:K15975 - - - - ko00000 - - - Glyoxalase HPHIIJEP_03963 224308.BSU19560 3.76e-146 411.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,1ZAQZ@1386|Bacillus 91061|Bacilli S Carboxylesterase yahD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH HPHIIJEP_03964 224308.BSU19550 1.11e-139 395.0 COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli,1ZQ88@1386|Bacillus 91061|Bacilli C nitroreductase yodC - - - - - - - - - - - Nitroreductase HPHIIJEP_03965 224308.BSU19540 2.63e-73 219.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,1ZH23@1386|Bacillus 91061|Bacilli K transcriptional yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR HPHIIJEP_03966 224308.BSU19530 5.64e-84 248.0 COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli,1ZG7P@1386|Bacillus 91061|Bacilli S tautomerase iolK - - - - - - - - - - - Tautomerase_2 HPHIIJEP_03967 224308.BSU19520 9.5e-125 367.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,1ZAYI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases gntP GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease HPHIIJEP_03968 224308.BSU19520 4.1e-147 424.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,1ZAYI@1386|Bacillus 91061|Bacilli EG COG2610 H gluconate symporter and related permeases gntP GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0008643,GO:0015075,GO:0015128,GO:0015144,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0034220,GO:0035429,GO:0042873,GO:0042879,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease HPHIIJEP_03969 1178540.BA70_14055 5.59e-14 67.4 2B7QS@1|root,320WV@2|Bacteria,1UAN7@1239|Firmicutes,4IM0U@91061|Bacilli,1ZIN1@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03970 224308.BSU19490 2.88e-103 299.0 2DR1M@1|root,339SJ@2|Bacteria,1VMD6@1239|Firmicutes,4HRV5@91061|Bacilli,1ZGEB@1386|Bacillus 91061|Bacilli S COG0071 Molecular chaperone (small heat shock protein) yozR - - - - - - - - - - - CS HPHIIJEP_03971 224308.BSU19480 1.64e-207 574.0 COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli,1ZD78@1386|Bacillus 91061|Bacilli S -transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA HPHIIJEP_03972 224308.BSU19479 4.37e-57 177.0 29HMR@1|root,304J1@2|Bacteria,1TWSW@1239|Firmicutes,4I5M0@91061|Bacilli,1ZJ8C@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03973 224308.BSU19470 2.32e-79 235.0 COG2120@1|root,COG2120@2|Bacteria,1VA8Q@1239|Firmicutes,4HKMK@91061|Bacilli,1ZH30@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF1806) yojF - - - - - - - - - - - DUF1806 HPHIIJEP_03974 224308.BSU19460 3.71e-161 451.0 COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,4HA2P@91061|Bacilli,1ZB3T@1386|Bacillus 91061|Bacilli S deacetylase yojG - - ko:K22135 - - - - ko00000,ko01000 - - - PIG-L HPHIIJEP_03975 224308.BSU19450 2.05e-193 537.0 COG1366@1|root,COG1366@2|Bacteria,1V1QF@1239|Firmicutes,4HGBT@91061|Bacilli,1ZDJX@1386|Bacillus 91061|Bacilli T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - ko:K17763 - - - - ko00000,ko03021 - - - STAS HPHIIJEP_03976 224308.BSU19440 1.69e-312 853.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli,1ZAX6@1386|Bacillus 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE HPHIIJEP_03978 224308.BSU19430 2.91e-139 394.0 COG1624@1|root,COG1624@2|Bacteria,1V3J8@1239|Firmicutes,4HHIB@91061|Bacilli,1ZGH7@1386|Bacillus 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacB GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N,YojJ HPHIIJEP_03979 224308.BSU19420 1.13e-293 801.0 COG1819@1|root,COG1819@2|Bacteria,1TSPC@1239|Firmicutes,4HRJW@91061|Bacilli,1ZRSZ@1386|Bacillus 91061|Bacilli CG UDP-glucoronosyl and UDP-glucosyl transferase yojK GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008194,GO:0016740,GO:0016757,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - - - - - - - - - - UDPGT HPHIIJEP_03980 224308.BSU19410 1.07e-266 734.0 COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat - - - ko:K19220,ko:K19223,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011 - CBM50 - LysM,NLPC_P60 HPHIIJEP_03981 224308.BSU19400 3.62e-142 400.0 COG2032@1|root,COG2032@2|Bacteria,1V652@1239|Firmicutes,4HH67@91061|Bacilli,1ZE46@1386|Bacillus 91061|Bacilli P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodC GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0046983,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu HPHIIJEP_03982 224308.BSU19390 4.45e-206 571.0 COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,4HBG4@91061|Bacilli,1ZAT6@1386|Bacillus 91061|Bacilli S ATPase family associated with various cellular activities (AAA) yojN - - ko:K04748 - - R00294 RC02794 ko00000 3.D.4.10 - - AAA_5,CbbQ_C HPHIIJEP_03983 224308.BSU19380 0.0 1238.0 COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,4HCPJ@91061|Bacilli,1ZD6R@1386|Bacillus 91061|Bacilli P Von Willebrand factor yojO - - - - - - - - - - - CobT_C,VWA HPHIIJEP_03984 224308.BSU19370 0.0 1879.0 COG0567@1|root,COG0567@2|Bacteria,1TRDW@1239|Firmicutes,4HAUI@91061|Bacilli,1ZAX3@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) odhA GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr HPHIIJEP_03985 224308.BSU19360 2.59e-264 728.0 COG0508@1|root,COG0508@2|Bacteria,1TP3C@1239|Firmicutes,4HBVM@91061|Bacilli,1ZBCB@1386|Bacillus 91061|Bacilli C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) odhB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding HPHIIJEP_03986 224308.BSU19350 3.31e-214 593.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli,1ZB6V@1386|Bacillus 91061|Bacilli S -transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF HPHIIJEP_03987 224308.BSU19340 2.52e-299 819.0 COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,4HAAI@91061|Bacilli,1ZBC5@1386|Bacillus 91061|Bacilli S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family yocR - - ko:K03308 - - - - ko00000 2.A.22.4,2.A.22.5 - - SNF HPHIIJEP_03988 224308.BSU19330 3.91e-211 582.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HAX6@91061|Bacilli,1ZB6Q@1386|Bacillus 91061|Bacilli P Superoxide dismutase sodF - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - DUF2935,Sod_Fe_C,Sod_Fe_N HPHIIJEP_03989 224308.BSU19320 0.0 1221.0 COG1657@1|root,COG1657@2|Bacteria,1TRRG@1239|Firmicutes,4HA2Q@91061|Bacilli,1ZBBW@1386|Bacillus 91061|Bacilli I COG1657 Squalene cyclase sqhC - 4.2.1.137 ko:K18115 - - - - ko00000,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N HPHIIJEP_03990 224308.BSU19310 0.0 996.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus 91061|Bacilli C Belongs to the aldehyde dehydrogenase family dhaS - 1.2.1.3,1.2.1.39 ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh HPHIIJEP_03991 224308.BSU19300 1.91e-42 138.0 2E3WX@1|root,32YU3@2|Bacteria,1VFHJ@1239|Firmicutes,4HPQ5@91061|Bacilli,1ZITX@1386|Bacillus 91061|Bacilli - - yozC - - - - - - - - - - - - HPHIIJEP_03992 224308.BSU19290 2.17e-74 223.0 arCOG12631@1|root,303Q6@2|Bacteria,1VFEW@1239|Firmicutes,4IKCU@91061|Bacilli,1ZGGS@1386|Bacillus 91061|Bacilli S Bacterial PH domain yozO - - - - - - - - - - - bPH_1 HPHIIJEP_03993 224308.BSU19280 1.83e-49 157.0 2EFR8@1|root,339HA@2|Bacteria,1VHR4@1239|Firmicutes,4HQMM@91061|Bacilli,1ZIJX@1386|Bacillus 91061|Bacilli - - yocN - - - - - - - - - - - - HPHIIJEP_03994 224308.BSU19270 2.94e-55 172.0 2EHWS@1|root,33BND@2|Bacteria,1VPU6@1239|Firmicutes,4HRS1@91061|Bacilli,1ZHT1@1386|Bacillus 91061|Bacilli - - yozN - - - - - - - - - - - - HPHIIJEP_03995 224308.BSU19260 5.43e-114 326.0 COG0071@1|root,COG0071@2|Bacteria,1VIHI@1239|Firmicutes,4HPSX@91061|Bacilli,1ZFR8@1386|Bacillus 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family yocM - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 HPHIIJEP_03996 224308.BSU19259 3.93e-41 135.0 29S4P@1|root,30D96@2|Bacteria,1UB0T@1239|Firmicutes,4IMDM@91061|Bacilli,1ZJWA@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_03997 224308.BSU19250 4.29e-70 211.0 2B51N@1|root,31XUX@2|Bacteria,1U9H0@1239|Firmicutes,4IJM1@91061|Bacilli,1ZGBD@1386|Bacillus 91061|Bacilli - - yocL - - - - - - - - - - - - HPHIIJEP_03998 224308.BSU19240 2.87e-107 310.0 COG1734@1|root,COG1734@2|Bacteria,1W0NA@1239|Firmicutes,4HZ77@91061|Bacilli,1ZG5H@1386|Bacillus 91061|Bacilli T general stress protein yocK - - - - - - - - - - - zf-dskA_traR HPHIIJEP_03999 224308.BSU19230 1.46e-147 415.0 COG1182@1|root,COG1182@2|Bacteria,1UGCK@1239|Firmicutes,4HAPQ@91061|Bacilli,1ZR58@1386|Bacillus 91061|Bacilli I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity azoR - - ko:K01118 - - - - ko00000,ko01000 - - - Flavodoxin_2 HPHIIJEP_04000 224308.BSU19220 0.0 1160.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,1ZC4U@1386|Bacillus 91061|Bacilli L DNA helicase recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind HPHIIJEP_04001 224308.BSU19210 3.92e-173 486.0 COG1388@1|root,COG3584@1|root,COG1388@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4HCGU@91061|Bacilli,1ZFSM@1386|Bacillus 91061|Bacilli M COG1388 FOG LysM repeat yocH - - - - - - - - - - - 3D,LysM HPHIIJEP_04003 224308.BSU19200 4.71e-135 383.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,1ZC1V@1386|Bacillus 91061|Bacilli T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg HPHIIJEP_04004 224308.BSU19190 4.09e-251 691.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,1ZBZR@1386|Bacillus 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 HPHIIJEP_04005 224308.BSU19180 2.31e-257 705.0 COG3239@1|root,COG3239@2|Bacteria,1TP3B@1239|Firmicutes,4H9TS@91061|Bacilli,1ZAYJ@1386|Bacillus 91061|Bacilli I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase HPHIIJEP_04006 224308.BSU19170 4.53e-239 656.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,1ZQ9Y@1386|Bacillus 91061|Bacilli V peptidase S66 yocD - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 HPHIIJEP_04007 224308.BSU19160 1.32e-122 348.0 28PIX@1|root,2ZC8R@2|Bacteria,1V2BK@1239|Firmicutes,4HGS0@91061|Bacilli,1ZG7B@1386|Bacillus 91061|Bacilli - - yocC - - - - - - - - - - - Acetyltransf_1 HPHIIJEP_04008 224308.BSU19150 2.6e-185 515.0 297WE@1|root,2ZV2Y@2|Bacteria,1VW2D@1239|Firmicutes,4HW4N@91061|Bacilli,1ZSJT@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_04009 1051501.AYTL01000030_gene2262 3.97e-119 341.0 COG2322@1|root,COG2322@2|Bacteria,1V3KT@1239|Firmicutes,4HH92@91061|Bacilli,1ZFN2@1386|Bacillus 91061|Bacilli S membrane yozB - - ko:K08976 - - - - ko00000 - - - DUF420 HPHIIJEP_04010 224308.BSU19130 9.39e-157 440.0 COG0741@1|root,COG0741@2|Bacteria,1VD4A@1239|Firmicutes,4HN7R@91061|Bacilli,1ZDE7@1386|Bacillus 91061|Bacilli M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) yocA - - - - - - - - - - - CHAP,Lysozyme_like HPHIIJEP_04011 224308.BSU19120 8.12e-69 208.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,1ZGXI@1386|Bacillus 91061|Bacilli K transcriptional czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 HPHIIJEP_04012 224308.BSU19110 5.2e-121 346.0 2DUZZ@1|root,32UY8@2|Bacteria,1VAX8@1239|Firmicutes,4HMKW@91061|Bacilli,1ZF86@1386|Bacillus 91061|Bacilli - - yobW - - - - - - - - - - - DUF1453 HPHIIJEP_04013 224308.BSU19100 3.36e-221 610.0 COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,4HIPG@91061|Bacilli,1ZQBA@1386|Bacillus 91061|Bacilli K WYL domain yobV - - - - - - - - - - - HTH_11,WYL HPHIIJEP_04014 224308.BSU19090 8.64e-112 321.0 COG3708@1|root,COG3708@2|Bacteria,1VXXE@1239|Firmicutes,4HWWS@91061|Bacilli,1ZI69@1386|Bacillus 91061|Bacilli K Bacterial transcription activator, effector binding domain - - - - - - - - - - - - Cass2,GyrI-like HPHIIJEP_04015 224308.BSU19080 4.49e-168 469.0 COG0491@1|root,COG0491@2|Bacteria,1TPPD@1239|Firmicutes,4HB0S@91061|Bacilli,1ZCBS@1386|Bacillus 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yobT - - - - - - - - - - - Lactamase_B HPHIIJEP_04016 224308.BSU19070 3.46e-124 355.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,1ZCT7@1386|Bacillus 91061|Bacilli K Transcriptional regulator yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG HPHIIJEP_04017 224308.BSU19060 9.8e-179 497.0 COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,4HJ2D@91061|Bacilli,1ZQJP@1386|Bacillus 91061|Bacilli J FR47-like protein - GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - - - - - - - - - - Acetyltransf_1 HPHIIJEP_04018 224308.BSU19050 1.56e-172 481.0 COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V4EJ@1239|Firmicutes,4HJ2M@91061|Bacilli,1ZF13@1386|Bacillus 91061|Bacilli K helix_turn_helix, arabinose operon control protein yobQ - - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 HPHIIJEP_04019 224308.BSU19040 6.09e-70 211.0 COG0073@1|root,COG0073@2|Bacteria,1V6N9@1239|Firmicutes,4HINY@91061|Bacilli,1ZH62@1386|Bacillus 91061|Bacilli J tRNA-binding protein csaA GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K06878 - - - - ko00000 - - - tRNA_bind HPHIIJEP_04020 224308.BSU19020 0.0 959.0 COG1231@1|root,COG1231@2|Bacteria,1TRJC@1239|Firmicutes,4HBN4@91061|Bacilli,1ZBU2@1386|Bacillus 91061|Bacilli E COG1231 Monoamine oxidase iaaM - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase HPHIIJEP_04021 224308.BSU19010 1.02e-95 281.0 COG4282@1|root,COG4282@2|Bacteria,1W2DK@1239|Firmicutes,4I1HJ@91061|Bacilli,1ZHYP@1386|Bacillus 91061|Bacilli G SMI1 / KNR4 family yokH - - - - - - - - - - - SMI1_KNR4 HPHIIJEP_04022 224308.BSU19000 0.0 1100.0 COG5444@1|root,COG5444@2|Bacteria,1V897@1239|Firmicutes,4HIMS@91061|Bacilli,1ZIHP@1386|Bacillus 91061|Bacilli L A nuclease of the HNH/ENDO VII superfamily with conserved LHH - - - ko:K21487 - - - - ko00000,ko01000,ko02048 - - - EndoU_bacteria,LHH,LXG HPHIIJEP_04023 224308.BSU18990 2.24e-110 317.0 2E17N@1|root,32WNB@2|Bacteria,1VDC9@1239|Firmicutes,4HHCQ@91061|Bacilli,1ZFJS@1386|Bacillus 91061|Bacilli S SMI1-KNR4 cell-wall - - - ko:K21488 - - - - ko00000,ko02048 - - - SUKH_5 HPHIIJEP_04024 997346.HMPREF9374_1613 6.23e-61 189.0 2927C@1|root,30BU7@2|Bacteria,1U8NW@1239|Firmicutes,4IIKY@91061|Bacilli,27D1V@186824|Thermoactinomycetaceae 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_04026 224308.BSU18840 7.53e-157 439.0 COG0726@1|root,COG0726@2|Bacteria,1UZ2U@1239|Firmicutes,4HVCK@91061|Bacilli,1ZEQK@1386|Bacillus 91061|Bacilli G Glycosyl hydrolases family 11 xlnB GO:0005575,GO:0016020 3.2.1.8 ko:K01181 - - - - ko00000,ko01000 - - - Glyco_hydro_11 HPHIIJEP_04027 224308.BSU18830 0.0 1652.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,1ZAW5@1386|Bacillus 91061|Bacilli GT phosphoenolpyruvate synthase pps - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N HPHIIJEP_04030 224308.BSU18800 2.97e-214 592.0 COG2367@1|root,COG2367@2|Bacteria,1TQFB@1239|Firmicutes,4HAQ1@91061|Bacilli,1ZBKB@1386|Bacillus 91061|Bacilli V beta-lactamase penP GO:0005575,GO:0005576 3.5.2.6 ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 HPHIIJEP_04031 224308.BSU18790 2.07e-148 417.0 COG0693@1|root,COG0693@2|Bacteria,1TPJK@1239|Firmicutes,4HGTS@91061|Bacilli,1ZCPK@1386|Bacillus 91061|Bacilli S DJ-1/PfpI family lin0465 - - - - - - - - - - - DJ-1_PfpI HPHIIJEP_04032 224308.BSU18780 5.41e-100 290.0 29QTX@1|root,30BTX@2|Bacteria,1U8NQ@1239|Firmicutes,4IIKN@91061|Bacilli,1ZNRJ@1386|Bacillus 91061|Bacilli - - yoaW - - - - - - - - - - - - HPHIIJEP_04033 224308.BSU18770 1.11e-202 561.0 COG0697@1|root,COG0697@2|Bacteria,1U3VF@1239|Firmicutes,4IQWZ@91061|Bacilli,1ZHPV@1386|Bacillus 91061|Bacilli EG EamA-like transporter family yoaV - - - - - - - - - - - EamA HPHIIJEP_04034 224308.BSU18760 1.06e-199 554.0 COG0583@1|root,COG0583@2|Bacteria,1V275@1239|Firmicutes,4HCKR@91061|Bacilli,1ZMPJ@1386|Bacillus 91061|Bacilli K LysR substrate binding domain yoaU - - - - - - - - - - - HTH_1,LysR_substrate HPHIIJEP_04035 224308.BSU18750 1.63e-190 528.0 COG3739@1|root,COG3739@2|Bacteria,1TSSG@1239|Firmicutes,4H9MC@91061|Bacilli,1ZCEJ@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF817) yoaT - - - - - - - - - - - DUF817 HPHIIJEP_04036 279010.BL00569 1.21e-40 134.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1ZHUY@1386|Bacillus 91061|Bacilli K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 HPHIIJEP_04037 224308.BSU18730 3.22e-98 286.0 293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli,1ZFS5@1386|Bacillus 91061|Bacilli S Protein of unknown function (DUF2975) yoaS - - - - - - - - - - - DUF2975 HPHIIJEP_04038 224308.BSU18720 1.04e-217 600.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,4HCPD@91061|Bacilli,1ZBNK@1386|Bacillus 91061|Bacilli V vancomycin resistance protein yoaR - - - - - - - - - - - PG_binding_4,VanW HPHIIJEP_04039 224308.BSU18710 4.94e-109 314.0 2EV9F@1|root,33IVQ@2|Bacteria,1VQIU@1239|Firmicutes,4HRBH@91061|Bacilli,1ZQPK@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_04040 224308.BSU18690 1.42e-25 102.0 COG0454@1|root,COG0456@2|Bacteria,1UHVP@1239|Firmicutes,4ISAV@91061|Bacilli,1ZS4D@1386|Bacillus 91061|Bacilli K YoaP-like yoaP - - - - - - - - - - - Acetyltransf_1,YoaP HPHIIJEP_04042 224308.BSU18670 3.62e-292 796.0 COG2140@1|root,COG2140@2|Bacteria,1TPC2@1239|Firmicutes,4HA6V@91061|Bacilli,1ZBBS@1386|Bacillus 91061|Bacilli G Oxalate decarboxylase oxdD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0033609,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046564,GO:0071704 4.1.1.2 ko:K01569 ko00630,ko01100,map00630,map01100 - R00522 RC00321 ko00000,ko00001,ko01000 - - iYO844.BSU18670 Cupin_1 HPHIIJEP_04045 224308.BSU18660 5.08e-171 476.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,1ZCQB@1386|Bacillus 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP HPHIIJEP_04046 224308.BSU18650 9.68e-251 687.0 COG3866@1|root,COG3866@2|Bacteria,1VQVQ@1239|Firmicutes,4HTPK@91061|Bacilli 91061|Bacilli G Amb_all - - 4.2.2.10 ko:K01732 - - - - ko00000,ko01000 - - - Pec_lyase_C HPHIIJEP_04047 224308.BSU18640 1.79e-145 411.0 COG3619@1|root,COG3619@2|Bacteria,1VBZN@1239|Firmicutes,4HMQK@91061|Bacilli,1ZFAA@1386|Bacillus 91061|Bacilli S Membrane yoaK - - - - - - - - - - - DUF1275 HPHIIJEP_04048 224308.BSU18630 2.61e-171 477.0 COG4305@1|root,COG4305@2|Bacteria,1UYVA@1239|Firmicutes,4HTET@91061|Bacilli,1ZMHI@1386|Bacillus 91061|Bacilli G Endoglucanase C-terminal domain subunit and related proteins yoaJ - - ko:K20628 - - - - ko00000 - - - DPBB_1,Pollen_allerg_1 HPHIIJEP_04049 224308.BSU18620 0.0 959.0 COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,4HA4I@91061|Bacilli,1ZDRC@1386|Bacillus 91061|Bacilli Q COG2368 Aromatic ring hydroxylase yoaI - 1.14.14.9 ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 - R02698,R03299 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N HPHIIJEP_04050 224308.BSU18610 1.58e-282 786.0 COG0840@1|root,COG5278@1|root,COG0840@2|Bacteria,COG5278@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,1ZMP8@1386|Bacillus 91061|Bacilli NT methyl-accepting chemotaxis protein yoaH - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,dCache_1 HPHIIJEP_04051 224308.BSU18600 2.99e-55 173.0 2EIXM@1|root,2ZSX9@2|Bacteria,1W2TZ@1239|Firmicutes,4I06A@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF4025) - - - - - - - - - - - - DUF4025 HPHIIJEP_04052 224308.BSU18596 1.46e-19 79.0 2C1AY@1|root,2ZPBJ@2|Bacteria,1W5BI@1239|Firmicutes,4I1SU@91061|Bacilli,1ZK8V@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - - HPHIIJEP_04054 1051501.AYTL01000030_gene2213 1.03e-44 146.0 2CH62@1|root,32S5C@2|Bacteria,1VD6E@1239|Firmicutes,4HKZ3@91061|Bacilli,1ZI0G@1386|Bacillus 91061|Bacilli - - yoaF - - - - - - - - - - - - HPHIIJEP_04055 224308.BSU18570 0.0 1357.0 COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4HBA3@91061|Bacilli,1ZAU8@1386|Bacillus 91061|Bacilli C belongs to the prokaryotic molybdopterin-containing oxidoreductase family yoaE - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding HPHIIJEP_04056 224308.BSU18560 3.92e-233 642.0 COG0111@1|root,COG0111@2|Bacteria,1UY3Y@1239|Firmicutes,4HMWA@91061|Bacilli,1ZENF@1386|Bacillus 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family yoaD - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C HPHIIJEP_04057 224308.BSU18550 0.0 952.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4HBRJ@91061|Bacilli,1ZMJ7@1386|Bacillus 91061|Bacilli G FGGY family of carbohydrate kinases, C-terminal domain lsrK - 2.7.1.189 ko:K11216 ko02024,map02024 - R11183 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N HPHIIJEP_04058 224308.BSU18540 2.24e-300 819.0 COG0477@1|root,COG2814@2|Bacteria,1TRNB@1239|Firmicutes,4HCAI@91061|Bacilli,1ZCJH@1386|Bacillus 91061|Bacilli EGP the major facilitator superfamily yoaB - - - - - - - - - - - MFS_1 HPHIIJEP_04059 224308.BSU18530 2.7e-121 346.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,1ZGGH@1386|Bacillus 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins yoaA - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 HPHIIJEP_04060 224308.BSU18520 1.06e-182 508.0 28PVT@1|root,2ZCGB@2|Bacteria,1V3TG@1239|Firmicutes,4HHU4@91061|Bacilli,1ZG2Q@1386|Bacillus 91061|Bacilli - - yoxB - - - - - - - - - - - UDG HPHIIJEP_04061 224308.BSU18510 1.15e-54 172.0 COG4768@1|root,COG4768@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF948) yoxC - - - - - - - - - - - DUF948 HPHIIJEP_04062 224308.BSU18500 3.77e-158 444.0 COG0300@1|root,COG0300@2|Bacteria,1UG37@1239|Firmicutes,4HC7Y@91061|Bacilli,1ZDQ3@1386|Bacillus 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family fabG - 1.1.1.100 ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short HPHIIJEP_04063 224308.BSU18490 5.37e-79 235.0 COG1695@1|root,COG1695@2|Bacteria,1V4I3@1239|Firmicutes,4HHBU@91061|Bacilli,1ZGU9@1386|Bacillus 91061|Bacilli K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat rtp - - - - - - - - - - - RTP HPHIIJEP_04064 224308.BSU18480 2.72e-185 517.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,1ZCWZ@1386|Bacillus 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU18480 F420_oxidored,P5CR_dimer HPHIIJEP_04065 224308.BSU18470 3.86e-261 716.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,1ZAPU@1386|Bacillus 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA HPHIIJEP_04066 224308.BSU18460 2.61e-205 569.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HA1X@91061|Bacilli,1ZCDN@1386|Bacillus 91061|Bacilli K Transcriptional regulator gltC GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - ko:K09681 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate HPHIIJEP_04067 224308.BSU18450 0.0 2995.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,1ZBFF@1386|Bacillus 91061|Bacilli E glutamate synthase gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase HPHIIJEP_04068 224308.BSU18440 0.0 999.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,1ZC3C@1386|Bacillus 91061|Bacilli E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 HPHIIJEP_04069 224308.BSU18430 4.18e-237 652.0 COG0604@1|root,COG0604@2|Bacteria,1TRRF@1239|Firmicutes,4HBSF@91061|Bacilli,1ZC7U@1386|Bacillus 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases yogA - - ko:K13955 - - - - ko00000 - - - ADH_N,ADH_zinc_N ## 3798 queries scanned ## Total time (seconds): 3.803847312927246 ## Rate: 998.46 q/s