LOCUS       c00001_gnlPro..        23236 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HPHIIJEP_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 15:13:24
            Original ID  :: gnl|Prokka|HPHIIJEP_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3720157
            Orig. end    :: 3743393
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23236
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3730157:3733393]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13236
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..23236
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23236
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="7"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             329..1174
                     /locus_tag="ctg1_3586"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     CDS             1272..1721
                     /locus_tag="ctg1_3587"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEIMGTICGDDTILIICRTPEDTDGVKNRLLELL"
     CDS             1756..3486
                     /locus_tag="ctg1_3588"
                     /transl_table=11
                     /translation="LLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQEISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     CDS             3661..4941
                     /locus_tag="ctg1_3589"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQPSESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     CDS             5217..6020
                     /locus_tag="ctg1_3590"
                     /transl_table=11
                     /translation="VEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     CDS             6329..6442
                     /locus_tag="ctg1_3591"
                     /transl_table=11
                     /translation="MKKKKARKREGFFLDFLFEVGGELFLLLFRCVHKLFI"
     CDS             complement(6485..7633)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3592"
                     /sec_met_domain="Oxidored_FMN (E-value: 6e-122, bitscore:
                     405.0, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTIDNRIAVAPMTHYASN
                     EDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAI
                     QAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGE
                     ATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKA
                     ASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRG
                     ADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPDWTVK
                     VKEGREKQIETVIKGTDKDKYHLPEPLWQAIVNTPGWVPYKD"
     CDS             8136..8429
                     /locus_tag="ctg1_3593"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETIIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNS"
     CDS             8450..9064
                     /locus_tag="ctg1_3594"
                     /transl_table=11
                     /translation="MLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSGAVG
                     NGLFEKDINLAVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSIHV
                     NSGVASASGTETYFQSDYEGENSRRLASDIQSQLVSSLQTRDRGVKESDFYVITYSQMP
                     SVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             9143..9874
                     /locus_tag="ctg1_3595"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEDRVILSTFNHDSLALCSRLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEVLKKMRNSSIKVRPYTVNRPEDMKCLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             10001..10354
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3596"
                     /sec_met_domain="Thiolase_N (E-value: 5e-38, bitscore:
                     128.8, seeds: 30, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDANILVAGEWKA"
     CDS             10351..11181
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3597"
                     /sec_met_domain="Thiolase_N (E-value: 3e-53, bitscore:
                     178.7, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 8.5e-50, bitscore:
                     165.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGN
                     TAAMEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIR
                     RDTSLDQLAKLSPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFS
                     TTGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVN
                     VNGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             11206..12069
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3598"
                     /sec_met_domain="HCDH (E-value: 1e-37, bitscore: 126.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 6.3e-66, bitscore: 219.6,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKR
                     LKKQLDRDAEKGKRTVTEVKSVISRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRMCPSHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEERTS"
     CDS             12097..13236
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3599"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.5e-56, bitscore:
                     187.5, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.7e-28, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.8e-39, bitscore:
                     131.1, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGE
                     HGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPKLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADI
                     YITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANL
                     LGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISF
                     KLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYG
                     YMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKHLLGGT"
     CDS             13269..14387
                     /locus_tag="ctg1_3600"
                     /transl_table=11
                     /translation="MEEKQQYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRLPEESEMETLERKINSAASLPADHLRLLELLPEDTHPMDSLRTGLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLHTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPVFFSART
                     SGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS"
     CDS             14402..15820
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3601"
                     /sec_met_domain="MmgE_PrpD (E-value: 8.1e-152, bitscore:
                     503.6, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKTDRVIVEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALR
                     YPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGH
                     PSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDH
                     VLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATS
                     RGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPA
                     EFHAQTAAECAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYI
                     TAIGLLFGDITAQHYEAETANDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVH
                     FKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETL
                     QTMRVNEFVDMFCM"
     CDS             15838..16743
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3602"
                     /sec_met_domain="PEP_mutase (E-value: 2.6e-53, bitscore:
                     178.8, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEV
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQTAPSLIVVART
                     DARAQEGLDAAIKRSEAYIGAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             complement(16784..17020)
                     /locus_tag="ctg1_3603"
                     /transl_table=11
                     /translation="MSRLLALLILVIPGAISALGIKLMRDTLFGHTIKPFSALWLQGLS
                     GFIFFAIGLYVLAGFILYRDRKRNQVSPRFRKR"
     CDS             17173..19251
                     /locus_tag="ctg1_3604"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIK
                     EVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFDFPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             19376..20275
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3605"
                     /sec_met_domain="PTA_PTB (E-value: 4.9e-49, bitscore:
                     165.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGNSTKLNELTSSMQGHQVEIVHADTPEESAKLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAV
                     GNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPFALDNAVSQIAAA
                     QKKISGDVAGNADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAE
                     NKLYSIALAICASEEYTH"
     CDS             20287..21381
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3606"
                     /sec_met_domain="ELFV_dehydrog (E-value: 3.9e-10, bitscore:
                     37.7, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 4.4e-29,
                     bitscore: 98.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRM
                     WTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQ
                     GLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAK
                     AAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVD
                     PDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYA
                     PDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAE
                     ERIERMRRSRSQFLQNGHSVLSRR"
     CDS             21406..22491
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3607"
                     /sec_met_domain="Butyrate_kinase (E-value: 2.9e-153,
                     bitscore: 507.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQRFD
                     RIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDEMIEDLKSGY
                     AGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFHALNQK
                     AVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSPERAGTV
                     PAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKARFIYDAM
                     AYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVYPGENELQS
                     LAQGALRVLQGEEQSKQYRIE"
ORIGIN
        1 agaaagaagg cctttccgtg cgcgttgtga atgcgcgttt tattaagccg attgatgaaa
       61 agatgatgaa gagtatccta aaagaaggct tgccaatttt aacaattgaa gaagcggtct
      121 tagaaggcgg tttcggaagc tcgattttag aattcgctca tgatcaaggt gaatatcata
      181 ctccgatcga cagaatgggt atacctgatc ggtttattga acacggaagc gtaacagcgc
      241 ttcttgagga aattggactg acaaaacagc aggtggcaaa tcgtattaga ttactgatgc
      301 cgccaaagac acacaaagga attggatcat gacgtcaaag aaagaacgat tagatgtatt
      361 attagtggaa agagggctgg cggaaacgcg tgaaaaagcc aaaagagcca ttatggcggg
      421 gatcgtctat tcaaacgaaa accgcttgga caagcctgga gaaaaaattg accgcgacct
      481 tccgttaact gtcaaaggaa acccgctgag gtatgtgagc aggggcggct taaagctcga
      541 aaaagcgttg aaggaatttc ccgtctctgt caaagataaa attatgattg atattggctc
      601 ctccaccggc ggttttacgg actgcgcttt gcaaaatgga gctaaacagt catacgctgt
      661 ggatgtaggc tataatcagc ttgcatggaa gcttagacag gatgaacggg tcgtcgtgat
      721 ggaacggacg aactttcgtt atgcaacacc ggcagacttt acaaagggca tgccggagtt
      781 tgccacaatt gatgtgtcct ttatttcact gcggctcatc ctgcctgtcc taaggacttt
      841 actcgtaccg ggcagcgact gcatggctct agttaagcct cagtttgaag cgggacggga
      901 atccgtcggc aaaaaaggga ttgtcagaga tcctaaagtg catgctgatg tgctcaagcg
      961 aatgatcagt ttttctgccg ctgaaggcta tatctgtaaa ggcttgtcat tttctccaat
     1021 cacgggagga gacggaaata ttgagtttct ccttcatttg cattggccgg gagagggaca
     1081 ggaaggtcag gagctgccgg aagaagagat catgcgcgtt gtagaagaag cacataagac
     1141 gttaaaagaa aaaaaagcag atgtaccgga ataatagggc gctattattc cttttttctg
     1201 cattcatgta caatgtgcag agaatcatat aacataaaag aacagataag cttggaaata
     1261 gaggtgctta catgaacaaa ggccagaggc atattaaaat cagagagatc attacaagca
     1321 atgaaatcga aacgcaggat gaattggtcg acatgctaaa gcaggatgga tacaaagtaa
     1381 cgcaagccac ggtatcacgg gatattaaag aacttcacct tgtaaaagtg cctacaaata
     1441 acggttctta caaatacagt cttccggcgg accagcgttt caatccgctg tctaagctaa
     1501 agcgggcctt gatggacgca tttgtgaaaa tagactctgc aagccatatg atcgtactga
     1561 aaacgatgcc gggcaatgct caggcaatcg gggcgctgat ggacaatttg gactgggatg
     1621 aaattatggg gaccatttgc ggagatgaca cgattttaat tatttgccgg actcctgaag
     1681 atacagacgg tgtaaaaaac agactgcttg aactgctgta acagaatcta acaaagataa
     1741 gaggtgtaat gctgtttgtt agctgaacta tcgattaaaa actttgccat tattgaggaa
     1801 ctgacggttt cttttgaacg cgggcttacg gttttaacag gagaaaccgg agccggcaaa
     1861 tccattatca tagatgccat ttctctttta gtcggaggcc gcggatcatc tgaatttgtt
     1921 agatatgggg aagcaaaagc cgaacttgaa gggctgtttc tgttggagag cggccatcct
     1981 gttttaggcg tatgcgctga gcagggaatc gacgtttcag acgaaatgat cgtcatgaga
     2041 agggatatca gcacgagcgg gaaaagcgtt tgccgtgtca atggcaagct tgtcacgatt
     2101 gcctcgctaa gagagatcgg caggctttta ttagatattc acgggcagca cgataaccag
     2161 ctgttaatgg aagacgaaaa tcatctccag cttttggaca agtttgccgg ggccgaagtg
     2221 gaaagcgcgc tcaaaacgta tcaggaaggg taccagcggt atatgaagct gctcaaaaag
     2281 cttaagcagc tttctgaaag cgaacaggaa atggcccatc gtcttgatct tattcaattt
     2341 cagctcgaag aaatcgaatc ggcaaagctt gagcttaacg aagatgaaca gctccaagaa
     2401 gagcgccagg aaatttcaaa ctttgagaag atatatgaat cgctgcaaaa tgcatataac
     2461 gcgcttcgca gtgagcaggg cggattggac tgggtcggaa tggcttcagc gcagcttgaa
     2521 gatatctctg atattaacga accgctgaaa aaactgtctg aaagtgtttc gaactcctac
     2581 tatttgcttg aggatgccac atttcagatg agaaatatgc tggatgagct tgaatttgat
     2641 ccggaacgcc tgaactatat tgagacacga cttaatgaaa tcaaacagct gaaacgaaaa
     2701 tacggtgcca ctgttgaaga cattttggaa tatgcttcta aaattgaaga agagattgac
     2761 caaattgaaa acagggacag ccaccttcaa agcttgaaaa aggagcttga ctccgtcggc
     2821 aaagatgtcg cagtggaagc ggcaaatgtg tcacaaatcc gaaaaacatg ggcgaaaaag
     2881 ctggctgatg agattcatcg ggaattaaaa agcctgtaca tggaaaaatc aacttttgat
     2941 acggaattta aggtcagaac agcgtcacgc aatgaagagg cgccgcttgt aaacggccag
     3001 cccgttcagc tgactgaaca agggattgac ctggtgaagt ttttaatttc aaccaataca
     3061 ggcgagccgc tgaaatccct ttcgaaagtc gcttcaggtg gagagctgtc acgggtgatg
     3121 cttgccataa aaagcatttt ctcctcacaa caggatgtga catcgatcat ttttgacgag
     3181 gttgataccg gtgtaagcgg cagggtcgca caggcaatcg ctgagaagat ccataaggtg
     3241 tcaataggtt cacaagtgct gtgcattaca cacctgcctc aggtggctgc catggccgat
     3301 acgcatcttt atattgcgaa ggagttaaaa gacggcagaa cgacgacacg tgtcaagccg
     3361 ctctctaagc aggaaaaggt agcggaaatc gggcgcatga ttgcaggtgt cgaagtaacc
     3421 gacttaacga aacgccatgc gaaagaactt ttaaaacaag cggatcaagt caaaacaact
     3481 gggtaagctg cgcgagaagc gcagcttatt tttttcgtgt acatccattc gttcatcagt
     3541 atatccaatg tttttcttca tatgacagtt ataaataagc cgtcagaagg caaaattaaa
     3601 tgatgtagca gcaagtcata aagaaggtgt gggataggag cgaggagagt gaagtagtga
     3661 atgcccgata acatcagaaa agcagtaggt ttaattctcc ttgtttcgtt attaagtgta
     3721 ggtttatgca aaccgctaaa agaatattta ctgattccaa cgcaaatgag agtatttgaa
     3781 acccaaacac aagcgattga aacgagttta tcggtaaacg ctcagccatc agaatcctca
     3841 gaagcgttta cagtaaagaa agatccgcat gaaatcaagg tgacgggcaa aaaatcaggt
     3901 gagtcagaat tggtatacga tcttgccgga tttccaataa aaaaaacaaa agtgcatgtt
     3961 cttcctgatt taaaggttat acctggcgga caatcaatcg gtgtaaaact tcattccgtc
     4021 ggtgttcttg tcgtcggatt tcatcaaatc aatacaagtg aaggcaaaaa atctccggga
     4081 gaaacggctg gaattgaagc gggcgacatc attattgaga tgaatggaca gaaaattgaa
     4141 aaaatgaatg atgtagcccc atttattcaa aaggctggga aaactggtga atctttagat
     4201 ttactgatca aacgtgataa acagaaaatc aaaacgaagc tgatcccaga aaaggatgaa
     4261 ggagaaggca aatacagaat cgggttatat atcagagatt ctgctgccgg catcggcact
     4321 atgacctttt atgaaccgaa aacaaaaaaa tacggagcac ttggccacgt gatttccgat
     4381 atggacacaa agaaaccaat tgtagtggag aatggagaaa tcgttaaatc cactgtaaca
     4441 tcaattgaaa aagggacagg cggtaatccg ggagaaaaac tggcgcgatt ttcctcagaa
     4501 cgcaaaacga tcggggatat taacagaaac agcccgtttg ggattttcgg cacactgcat
     4561 cagccgattc aaaacaacat atcagatcaa gcattgccgg ttgcgttttc taccgaagtc
     4621 aaaaaagggc cggctgaaat tttaacggtt attgatgatg acaaagtaga aaaattcgat
     4681 attgaaatcg tcagcacaac gccgcaaaaa ttccctgcga caaaaggaat ggtgttgaaa
     4741 attaccgatc caaggctgtt gaaagaaaca ggaggcatcg tacaggggat gagcggaagc
     4801 ccgattattc aaaatggaaa agtgatcggt gctgtcaccc atgtatttgt aaatgacccg
     4861 acaagcggct acggtgttca tattgaatgg atgctgtcag aagcaggaat cgatatttat
     4921 ggaaaagaaa aagcaagttg actgccggag tttccggcag tttttttatt ttgatccctc
     4981 ttcacttctc agaatacata cggtaaaata tacaaaagaa gatttttcga caaattcacg
     5041 tttccttgtt tgtcaaattt catttttagt cgaaaaacag agaaaaacat agaataacaa
     5101 agatatgcca ctaatattgg tgattatgat ttttttagag ggtatatagc ggttttgtcg
     5161 aatgtaaaca tgtagcaagg gtgaatcctg ttaactacat ttggggagga agaaacgtgg
     5221 agaaaattaa agtttgtgtt gctgatgata atcgagagct ggtaagcctg ttaagtgaat
     5281 atatagaagg acaggaagac atggaagtga tcggcgttgc ttataacgga caggaatgcc
     5341 tgtcgctgtt taaagaaaaa gatcccgatg tgctcgtatt agatattatt atgccgcatt
     5401 tagacggact tgcggtttta gagaggctga gggaatcaga tctgaaaaaa cagccgaatg
     5461 tcattatgct gacagccttt ggacaggaag atgtcacgaa aaaggccgtc gatttaggcg
     5521 cgtcctactt tattctcaaa ccgtttgata tggaaaacct tgtcggccat atccgccagg
     5581 tcagcggaaa tgccagcagt gtgacgcatc gtgcgccatc atcgcaaagc agtattatac
     5641 gcagcagcca gcctgaacca aagaagaaaa atctcgacgc gagcatcaca agcattatcc
     5701 atgaaatcgg cgtcccagcc catattaaag gctatctcta tctgcgcgaa gcaatctcaa
     5761 tggtatacaa tgacatcgaa ttgctcggca gcattacaaa agtcctctat ccggacatcg
     5821 ccaaaaaatt taacacaacc gcaagccgtg tagaaagagc gatccgccat gcaattgaag
     5881 tggcatggag cagaggaaac attgattcca tttcctcgtt gtttggttat actgtcagca
     5941 tgacaaaagc taaaccgaca aattcggaat tcattgcaat ggttgcggat aagctgagat
     6001 tagaacataa ggcttcttaa acatgagctt attaagtggt cattaaatca aacgtctttt
     6061 atttattagt ttgcgctgat aaataggagg cgttttgttt tggggacatt tgtagtatgg
     6121 gagaagaata ttaagtatcc gcatatagta aaggataggt ttgaaaagta aggaaagcaa
     6181 atggcggtat tacctgcact cttggtccat tcatacatct tataggatca cgaagcatga
     6241 tcgaccctaa atatgtccgt tataaaatga aacctttctc ctgcaaaatc gtaagtaagg
     6301 cgtattcatg taaaaaggag acgtacgaat gaaaaagaaa aaagcaagaa agcgtgaggg
     6361 gtttttcctg gactttcttt tcgaagttgg tggggagctc tttcttttgc tgtttagatg
     6421 tgtacacaaa ctatttatat aaagggaaaa agactgccga atcgtttcgg cagtcttttg
     6481 cacattaatc tttataaggc acccagcctg gcgtgttcac aattgcttgc catagcggtt
     6541 caggcaaatg atatttatct ttatctgtgc ctttgatcac tgtttcgatt tgcttttcac
     6601 ggccttcttt tacttttacc gtccagtcag ggtcaactag aatttcgcgt cccatagcga
     6661 ctagcggaat accgttttcg atgacggcaa gcgcgtcatc agcggaatgg atggaaccga
     6721 cggcgatcag cggcactttg tttccgacac gttcattcaa taagtccatg cgtgtgcgag
     6781 tcggatctgc accgcggcgc gcttttgaat tcacgtccat cagtgagata tgaagataat
     6841 ccaattcttt atcccctaaa gcatcaacaa gcgtataagt ttcagtcatt gtcaatcccg
     6901 gtgtctcagg ttcttccgga gacagacggt agccgactaa gaacgcaccc ttcgcatgtt
     6961 ctgaagcggc ttttttcact tcatcgacaa tagcgagcgg gaaggctaat cttttttcat
     7021 cgcttcctcc ccagcgatcc gtgcgctggt tggttttcgg agaataaaac tgctgaatta
     7081 agtagccgtt tgcaccgtga atttcgacac cgtcaaagcc ggcttcaatg gcgcgtcttg
     7141 tcgcttctcc aaacgccttc acaatgtttt ccacttcttc ttcttttaat gcgcgagcaa
     7201 tttgtttgcc gttatcaaac acgtcacttg gccccacaac atcctgttga ggaacgagct
     7261 cagacgggca ctcaataccg ccgtgatgaa tttgcacaac ggctttagcg ccttgtgcct
     7321 gaatggcttg tgctaacttt tttaaacctg gaatgttgga atcgtcatgg atggccggct
     7381 gcccggggaa tgcttttccg tccggtgtaa catttgcgca ggctgtaatc accattccca
     7441 tctcttttga acgggggatg atgtagtcga gctccgcttc agatattgta ccgtcttcat
     7501 tagaagcgta atgagtcatt ggtgctactg cgatccggtt gtcgattgtg acgccgcttt
     7561 taaacgtaaa tggttcaaaa agtggcttat acttaggatt catttgatca tcttctttcg
     7621 tttggattcg cacatattct agcctatatg taaaaattaa tgcaattgat ctgctttacc
     7681 gactgaatat cttgagtgca gagtgatgtt ttcgccgctc tttttcgggg cctttgtagc
     7741 cgccgctgat ttggtggccg atggagcatg tgatgacagc tgccgccagc agcagaacga
     7801 attttttcat ggctttaact tctttcaata aagtaaatat cctttaaaag gttacgcttg
     7861 gctgacccac ccgtcaaacg atttgctcac cctattctca aattttttaa aatgaataaa
     7921 aagttgcttc tttccgctaa ttttttctaa ttgacgcctc aattagagcc atcctcatag
     7981 acaaatctgc tcgttatctt tctaacaaca ggaaatgatc gggtcgtata gcccttttga
     8041 aaatcatgga acttgctcgc ctgcattcgc gttgtcttta caaattcgcc attctggtca
     8101 aagataaaag ccaaacatca ggaagaggtg gtcatgtgaa acaaacggtt cttttgctgt
     8161 ttactgcgct ctttctttcg gggtgcagtg ttgcaagtgc ggatgactca gtgccaaggt
     8221 ttaccgaaga gggaaaatac attggctcgg ctgatcctca tacgattgcg gtttctctta
     8281 atggagaaga aaccataata caagttccga aggataaacg tgatgaatgt gaatcactgc
     8341 cagatcagac acatgtcctg gtgaaatata caaagaagga taatggaact ttacagctgg
     8401 aagatattca gctgcgaaag aactcgtgac cggagggagt aagttgagaa tgttatggag
     8461 gagcttggcg ctgtgcggat tggctttgac gctcgcgcct tgtgcacagg cagcagagcc
     8521 gatagaaggg aaaacagtgt atattgatgc cggacacggc ggtgaagaca gtggagcggt
     8581 cggaaacggg ctctttgaaa aggatattaa tttggctgtc tcagagcatg tgacagacaa
     8641 actaaaagag gagggagcca atcctgttgc atcccggtct gacgatcatt ttctgacctt
     8701 ggaggaaaga gtggctaagg caagtgccaa tcaggctgac ctttttgtca gcattcatgt
     8761 gaattcaggg gttgcttcag cttcaggaac agaaacgtat tttcaatctg attatgaagg
     8821 ggagaacagc cggcgtctgg catccgatat tcagtcacag ctcgtttcat ccttacaaac
     8881 gagagacagg ggcgtgaaag aatcagactt ttacgtcatt acatattcac aaatgccaag
     8941 tgtgttggcg gagcttgggt ttatcacgaa cagttctgat gcggacaagc tgggaagtga
     9001 agaataccag caaaaggccg cagatgcgat tgtcaacggc attgattctt attatgatca
     9061 gtagattgat acagccttaa tcctagagtg gagccgacaa aataagtata atggagaaaa
     9121 ctttagggtt tgaggtgaaa cgatgacaaa gatttttgcc caccgggggg catcaggtca
     9181 atttcccgaa aatacaatgc ttgcatttga aaaaggaatt gaagccggag cggatgggat
     9241 agagcttgat gtacagctga cgaaagacgg acgcattgtt gtgattcatg atgaaagact
     9301 taatcgcacg acatcactta aaggattcgt gaaggataca gcctatgatg aggtaaagac
     9361 tgcgaatgcg gccgctggtc acgatcaagc gtacagcgat ataaaagtgc cgctgctaga
     9421 agatgtgctc tcgtgggcgg taaaaaagga ttttctcatc aacattgaat taaaaaacag
     9481 cgtgatccgc tatgagggaa tggaagaaaa agtgctggag gcagtgaagc gattcaatgt
     9541 agaggacaga gtcatcctat ccacgtttaa tcatgacagc ttggcgctat gctcccggct
     9601 tgcgccgcat atcgaacggg cagtattaac ttcagatgtg ctttatcagg cagatcgata
     9661 tatcgcgtct attccggctt ccggctatca cccgaagtta aacagcccag gggtcacaga
     9721 tgaagtgctg aagaaaatga ggaacagttc gattaaggta aggccgtata cagtcaatcg
     9781 tccggaagat atgaagtgtc tcattgaagc gggagcagac ggcatgttta ccgactttcc
     9841 agaaaaggct tcggcattgc tgaaaaatga atagttgtta gaaggaggct gtttgatgca
     9901 gccttctttt ttcattcatt catgcccttt tcaaagcata cattcataga agacaactag
     9961 aaattgtaag cgctgtctat cttctgaatg aggtgaaacc atgaggaaaa cagtcattgt
    10021 aagtgctgca agaactccat ttggcaaatt cggcggagtt ttgaaagagg tgaaagctgc
    10081 tgagcttggg ggcattgtga tgaaggaggc gctgcaacgg gctggagtct ctggagatga
    10141 tgtagaagga aacgtcatgg gcatggttgt ccaggccggc tcagggcaga taccttcccg
    10201 tcaagctgcc cgtctggcgg gaatgccttg gagtgtgccg tcagaaacac tgaataaagt
    10261 ctgtgcttcc ggccttcgtg ctgtcacttt atgtgatcaa atgattcggg cgcaggatgc
    10321 gaacatactt gttgcggggg aatggaaagc atgagcaata ttccgtatgc cgttcccgcc
    10381 gggcgctggg gagcacggat gggggacggc gagcttaggg acttaatggt gtatgacgga
    10441 ttaacgtgcg catttgacga ggtgcacatg gctgttcacg gaaatacagc tgccatggaa
    10501 tatgcaatct cacgaagaga gcaggacgaa tgggcgttga gaagtcatgc aagggcagct
    10561 aaggctgccg atgaagggaa gtttcaggat gaaattgttc ccgtcaactg gatcggtcga
    10621 aaaggaaaac caaacgttgt tgataaagat gaagcgattc gccgtgacac aagtctggat
    10681 cagctcgcga aactttctcc tatttatgca agtgacggtt ctatcacagc cggcaatgct
    10741 cctggagtca atgacggagc cggcgcgttc gtgctgatgt ctgaggaaaa agctgctgag
    10801 cttggcaaac ggcctctggc tacaattctt ggtttttcaa ctacgggaat gccagcgcac
    10861 gagctggcgg cagcgccggg atttgccatt aacaagctcc tgaaaaagaa cggtttaact
    10921 gtccaagata ttgacttgtt tgaagtaaat gaagcttttg cttcagttgt tttgacatgt
    10981 gaaaaaatcg taggtttcga tcttgaaaaa gtaaatgtaa atggcggtgc gatcgcgctc
    11041 ggccatccga tcggcgcgag cggggcgaga attctcatga cgcttgttta tgaattaaag
    11101 cggcggggag gggggctggg cgttgccgct atttgcagcg gggcagcaca gggagacgcc
    11161 gtcttagtgc aggttcatta aaacatgatg aaaaagggga tttgaatgga aatcaaacaa
    11221 atcatggtag ctggcgcagg tcagatggga agcggaattg ctcaaacagc tgccgacgcg
    11281 ggcttttatg tgcggatgta tgatgtgaat ccagaggccg ctgaggcagg attgaaacgg
    11341 ctgaagaaac agctggaccg tgatgctgag aaaggaaaaa ggaccgtgac ggaagtgaag
    11401 agcgtaatca gccgcatttc gatttctcaa acgcttgagg aggcagagca tgcggacatt
    11461 gtgattgagg ctatcgcaga aaacatggcg gcaaaaactg aaatgtttaa aacacttgat
    11521 cgcatgtgcc cgtctcatac gattttggcc agcaatacat cttccttgcc tattacagaa
    11581 atcgctgctg taacaaaccg gcctcaacgg gttattggga tgcattttat gaatcccgtc
    11641 cctgtaatga agctggttga agtgattcgc ggcttggcta catcagaaga aacggcctta
    11701 gatgttatgg cattagcgga aaagatgggg aaaacagcgg tagaagtcaa tgattttcct
    11761 gggtttgttt ccaaccgtgt gcttcttcca atgattaatg aagccattta ttgcgtgtat
    11821 gagggagtgg cgaagccgga ggcaatagac gaagtgatga agctgggcat gaatcatccg
    11881 atgggtccgc ttgcattagc ggattttatc ggactggata cgtgtttatc aattatggaa
    11941 gtccttcact caggccttgg cgattccaaa taccgtcctt gcccgctgct ccgcaagtat
    12001 gtcaaagcag gctggcttgg caaaaagagc ggacgcggtt tttatgacta tgaggagagg
    12061 acttcctaaa gtctattcca tccgggggtg gccgagttgc atgtaaccca agagcaagtc
    12121 atgatgcgaa aaatggtgcg tgattttgca cgaaaagaaa ttgctcccgc tgcggaaatc
    12181 atggagaaaa cggacgaatt tccctttcag ctgatcaaaa aaatgggtga acacggactg
    12241 atgggaatac cggtgccgga acaatacggc ggtgccgggg cggacgttgt ttcttatatt
    12301 ttggcgattc atgagatttc tagaatcagt gcggctgtcg gcgtgatact ctccgttcat
    12361 acctcagtcg gcacgaatcc gattctgtat ttcggcaatg aagaacagaa gatgaaatat
    12421 ataccaaagc tcgcgtcagg agaccatttg ggcgcatttg cactaacgga gcctcactcg
    12481 gggtcggatg ccgggagcct ccgcacaaca gcaatcaaaa agaacggcaa atatctatta
    12541 aacggatcga aaatattcat aacgaatggc ggagcagctg atatctatat cacatttgct
    12601 ttaacagctc cagatcaagg caggcacgga atttcggctt ttattgttga aaaaaacaca
    12661 cccggtttta ccgttggaaa aaaagaaaga aagctggggc tttatggctc caatactacg
    12721 gaactgattt ttgataatgc agaagtgcct gaagccaatt tgcttggcaa agagggggat
    12781 ggctttcaca ttgccatggc gaatttaaat gtcggccgga tcggcattgc ggcacaggcc
    12841 ctcggaattg cagaggcggc tcttgagcat gccgttgatt atgcgaagca gcgagtgcaa
    12901 tttggaaggc cgatcgcagc caatcaaggc atatcattta agctggctga catggcgact
    12961 agggcagagg cggcaagaca tcttgtctac cacgccgcag accttcataa ccgcggccta
    13021 aattgtggaa aagaagcgtc tatggctaaa caatttgctt ccgatgcagc cgtgaaggca
    13081 gcgttagacg ccgttcaaat ttatggagga tatggctata tgaaggatta tccggttgag
    13141 cgcttgcttc gcgatgcaaa ggtgacgcaa atctatgaag ggacgaacga gattcaaaga
    13201 ctgattattt ccaagcattt gcttggcgga acctgataga caaaaacgca aaaacggagg
    13261 ttgaggatat ggaggagaaa cagcaatatt ctccagggtt ggacggtgtg attgcggcag
    13321 aaactcatat ttcttatctt gacacgcagt ccagccagat tttgataaga ggctatgatt
    13381 taatagaact ttctgaaaca aaaagctatc tggagcttgt ccatttattg ctggagggca
    13441 ggctgccaga agaaagtgaa atggagacgc tggaacgtaa aataaacagt gccgcaagcc
    13501 tgcctgctga tcatctccgt ctgcttgagc tgctccctga ggacactcat ccaatggata
    13561 gtctgcgtac cggcctgtcg gcacttgctg gctatgatcg gcaaattgat gatcggtctc
    13621 cttccgcaaa caaagaacgc gcctatcagc ttcttgggaa aatgcctgcc ctcactgctg
    13681 ccagctacag gatcattaat aagaaagaac cgattcttcc gcttcatacc ttatcctaca
    13741 gtgcgaattt tctctacatg atgacaggga aattgccgtc ttcattggaa gaacagattt
    13801 ttgaccggtc gctcgtcctg tacagtgagc atgagatgcc gaattcaacc tttgcggcca
    13861 gggtcattgc atctacacat tcagatcttt atggggcttt gactggggct gtcgcttccc
    13921 tgaaagggaa tcttcacgga ggagcaaacg aagctgtgat gtatttgctt ttggaggcaa
    13981 aaacgacatc tgattttgag cagcttctgc aaacaaaact gaaaagaaaa gaaaaaatca
    14041 tgggcttcgg ccaccgggtg tatatgaaaa aaatggaccc aagagcactc atgatgaaag
    14101 aggcgctgca gcaattatgc gataaagccg gtgaccatcg tttatatgag atgtgcgaag
    14161 cgggtgagcg gctgatggag aaggaaaaag ggctttaccc gaatttggat tactatgctg
    14221 ccccggtgta ttggatgctc ggcataccga ttcctttata tacgccggtc tttttcagcg
    14281 cgagaacgtc cggtttatgc gcccatgtga tcgaacagca tgccaataat cggctcttcc
    14341 gtccccgtgt cagttacatg ggcccgcgat atcaaacaaa atcatgaaag gagctggtag
    14401 aatgccgaaa acggatcgtg taatcgtaga aatcacagac tatgtgcttg aaaaagagat
    14461 tactagtgcc gaagcgtata caacagcggg gcatgtattg ctggataccc tgggctgcgg
    14521 gatcttggcg ctacgatatc cggaatgcac aaagctgctt ggcccgattg ttccaggaac
    14581 gactgtgccg aatggaagca aagtgccggg aacgtcatat gttctcgatc ctgtgagggc
    14641 agcgtttaat atcggctgca tgattcgctg gctcgattac aacgatacgt ggctggcggc
    14701 ggagtggggg catccatccg ataacttggg aggaatcctt gccgctgctg attatgtatc
    14761 aagagtgagg ctgtctgaag gaaaagagcc gttaacagta cgcgacgtac ttgagatgat
    14821 gatcaaagca cacgagattc aaggtgtgct ggcgttagaa aacagcttaa atcgagttgg
    14881 ccttgaccat gtgctgtttg tcaaagttgc gacaaccgct gttgcggcaa agcttttggg
    14941 cggcggaaga gaagaaatca aaaatgcgct ttcgaatgca tggattgaca atgcagcatt
    15001 gaggacatac cgccattcac cgaatacagg ctcgcgtaaa tcatgggcgg caggagatgc
    15061 aacgagcaga ggtgttcatt tggccctgat gtcgttaaaa ggggaaatgg gttatccgac
    15121 agccctgagt gcaccgggtt gggggttcca agacgtttta ttcaataaga aagagatcaa
    15181 gcttgcccgt ccgcttgacg cttatgtcat ggaaaatgtg ttatttaaag tgtcttatcc
    15241 tgcggaattt cacgcccaga cagcggcgga gtgcgccgtc attcttcacc cgcaggtaaa
    15301 gaaccggatt gacgagatag accgagttgt catcagaacg catgaatccg ctatccgtat
    15361 cattgataaa aaaggcccgc tccacaatcc ggcagaccgt gatcactgtc tccaatacat
    15421 tacagcaatc ggtttgcttt ttggtgatat caccgcacag cattatgaag ctgaaacagc
    15481 gaatgatccg agaatagata aacttcgtga taaaatggaa gtgactgaaa ataaaacata
    15541 taccgaggat tatttgaagc ctgataaacg ctccatctca aatgccgttc aggttcattt
    15601 taaagacgga acgagcacgg aaatggtgga atgtgagttt cccctcggcc atcgttttcg
    15661 aagagaggaa gcagtgccta aactgctgga aaagttttct gacaatctca aaacccattt
    15721 tcctgataaa cagcacaaac acatttatga gcgctgtacc agctatgaga cattacaaac
    15781 gatgcgcgta aatgaattcg tagacatgtt ctgcatgtaa aagggggatt ttgtttcatg
    15841 tcgtggatcg tcaataagca atcgtcacaa gaggagcttg ccgggcgttt ccgcaagctg
    15901 atgtcagcac cggacattct tcaaattccc ggcgcccatg acgggatggc cgctttgctt
    15961 gcgaaagaag tcggtttttc tgctatttat ttgtccggtg ctgcctatac agccagcagg
    16021 gggctgcctg atttagggat catcacatcg gcagagatag ctgaacgtgc caaagatctt
    16081 gtgcgtgcag ctgatctgcc tttgcttgtg gatatcgata cgggatttgg cggtgtctta
    16141 aatgccgccc gaacagcccg ggagatgctt gaagccaggg tagcagccgt tcaaatagaa
    16201 gaccagcagc tcccaaaaaa atgcggacat ttaaatggca aacagctagt tccgataaag
    16261 gaaatggcgc aaaaaataaa agccattaaa caaacggcac cctcccttat tgttgttgcc
    16321 cgtactgatg ccagggcgca ggaagggctt gatgccgcaa taaaacgttc agaggcttac
    16381 attggggcgg gagcggacgc aattttcccg gaagcgctac aggcggagaa tgaattccgc
    16441 cagtttgctg agcgtatccc cgttccgctc cttgcgaata tgactgaatt tgggaaaacg
    16501 ccgtattatc gtgccgatga attcgaagat atggggtttc acatggtgat atatcctgtc
    16561 acctcgcttc gagcggcggc aaaagcttgt gagcggatgt ttggtttgat gaaggagcac
    16621 ggctcacaaa aagaaggact tcatgatatg cagacacgaa aagaactgta cgatacgatt
    16681 tcttattatg actatgaagc gttagacaaa acgattgcca agaccgtttt gcctgacgaa
    16741 tagtgcaaca aaaaaagccg gagcattctc cggctttttt cagctatcgt tttctgaatc
    16801 gcggactgac ttgattgcgt tttctgtctc tgtataaaat gaacccggcc agcacataga
    16861 ggccgatcgc aaaaaagatg aatcctgaca acccttggag ccaaagagct gaaaatggct
    16921 tgattgtatg gccgaaaagt gtatctctca tcagtttaat gcctaaagca gaaatagccc
    16981 cggggatgac taatattaaa agcgcaagaa gtcggctcat cttcagaaaa cccctttatc
    17041 ttttcatttc ctttattgtc cagcggaaaa aatattttgt caagagaaga aaacgtggta
    17101 acatagggtt gtgcaaatta ttgcaacgga ataaataggt gtgcaaattt tttcatgcaa
    17161 aggggtatcg ggatgcaaaa ggtactgata gtaggtgccg gcaaaagggg aacggcgtta
    17221 ttacatattc tgattaaaac agccatcata gatatcattg ccgtagttga caaagacccc
    17281 gaagcgccgg gattgaaaga agcagaacag tatgggattg ccgtatcatc tgattggaaa
    17341 ccttacatac aacaaaaacc ggatatcgtc attcatacca ccggcgatca agccgtgttt
    17401 gacgagctcc ttcaaagaaa gcatgaagat accattgtca tgccaggaaa aatggcatac
    17461 atcgtttttc agctgatgga agaaaagcag cacctgattc aaatgctaaa agagcaaacc
    17521 tataaatatg acagaatttt taattccacc catgatggaa tgatttttat tgatatcaat
    17581 gaagaaatca ttctctttaa ccatatggcc gaaaaaatgg tcggaaaaaa acgtgaggaa
    17641 gtcattgggc gcccaataaa agaagtgatt ccgagcacta agatgccgcg gattttaaaa
    17701 acaagagtgc ctgaatacaa ccagaagcag ctgttaggcg atcatttgca aattgtgacc
    17761 acaagactgc cgattattga tgaaggcgga cgtctgctcg gggctctttg tgtgtttaaa
    17821 gatatcactg atgcggtcga gctggcagag gaagtgacca acttaaagca ggtccgtacg
    17881 atgctggagg caattattca atcctccgat gaggcgattt ctgtcgttga tgaaaacggc
    17941 atcggcctgc taatcaataa agcgtatacg aaaatgacgg ggctttctga aaaagaagtc
    18001 atcggcaagc ctgcaaacac tgatatttcc gaaggcgaaa gcatgcattt aaaggtgctt
    18061 gaaacaagac gtcctgtccg cggtgtcaga atgaaggtcg gcccgaatga aaaagaggtc
    18121 atcgttaatg tagcaccggt gattgtggac gggattttga aaggcagcgt cggcgtgatt
    18181 cacgatgttt ccgaaattaa aatgctgaca gcggagctta atcgcgccag acaaattatt
    18241 cgcacgcttg aagcgaaata cacgtttgac gacattatcg gcaaaagcga gcaaatgctg
    18301 gttgcgcttg agcaggcgaa gctcggtgcg aaaacaccgg caaccatctt gctgcgcggg
    18361 gaatcaggaa caggaaaaga actgttcgcc catgccatcc ataacgaaag tgaccggaaa
    18421 tacaataaat ttattcgcgt gaattgtgca gccctttctg aaaacctgct cgaatcagaa
    18481 ttgttcggct atgaggatgg tgcgttttca ggagcgaagc gcggcggtaa aaagggttta
    18541 tttgaggaag caaataacgg cagtattttc ttagatgaaa tcggtgagct gacacaaaat
    18601 atgcaggcca aattgctacg cgtccttcaa gaaaaggaaa tcgtcagagt gggcggcacg
    18661 aaagcgatcc ctgtcaacgt cagagtgatc gcggcgacaa atgtaaatat tgaaaaggcg
    18721 atggcggacg gaacattccg ggaagacctg tattaccgga tcaatcgcta tccgatctcc
    18781 atcccgcctt tgcggcagcg gttggaggac attgaagcat tgagcgtcag acttatccaa
    18841 aagatcaacc gggattacgg caggaatgta aaagggctct cacagcaagc cttgcgcgcc
    18901 ttatctgcct accattggcc tgggaatgtc cgggagcttg aaaatgtcct tggacgagcc
    18961 atgatttttc tgaatccgca tatggaatgg attgaaaaag atcacttgcc tgtattcgaa
    19021 cttgagcaaa aagaaaatga cacagatcag ggaacaggtt ttgattttcc ggatattgaa
    19081 ggcgaaaagc tgtctgtcgc agtagaaaaa tttgaagcgc atttgatcca gcaaacgctt
    19141 gaaaagcatc attttaaccg gacaaaaaca gcaaaagctc tcggtgtcag cattcggaac
    19201 ttatattaca aaatggataa atatggcctt gcaaatgaag gcatgcaata atttgcagaa
    19261 taaacgcaaa catctgcacg aatgtttcgg tatacctggt atgacagcac ccttaagagc
    19321 tggcatggaa cttgcataat aaaaggcgga gtcgaaacaa gaaaggtggt aacagatgaa
    19381 gctgaaagat ttaatcggca aagcgtcgat acacaaaaat aagaccattg cggttgctca
    19441 tgctgaggat gaggaagtga tccgggctgt aaagctggct gccgagcacc tatccgcccg
    19501 tttcttgtta acgggcaaca gcacaaaact gaacgagctg acatcatcca tgcaagggca
    19561 tcaagtggaa atcgtccatg ctgatactcc tgaggaatcg gcgaaattag cggttcgtgc
    19621 tgtacatcat aaaacagcgg acgttttaat gaaaggcaat gtgccgactt ctgttttgct
    19681 taaagcggta ttgaacagac aggaggggct tcggtcagca agtgtccttt ctcacgtggc
    19741 tgtcttcgat ataccggatt ttgaccggct gatgtttgtg acagattcgg caatgaatat
    19801 tgctccttcg ctggaagagc tccggcagat tttgcaaaat gccgttcatg tggcccatgc
    19861 agtagggaac aatatgccaa aagcagctgc ccttgcagcg gtcgaaacgg tgaacccaaa
    19921 aatggaagca accgtgaatg cagctgctct agctcaaatg tacaaaaggg gccagatcaa
    19981 aggctgcatt gttgatggac cgtttgcttt ggataacgca gtttcacaaa ttgccgcggc
    20041 ccagaaaaaa atttcgggag acgtagcggg caacgcagat atccttctcg tcccaacaat
    20101 tgaggccggc aatattttat ataaatcact gatttatttt gccaaggcca gcgtggcggc
    20161 tgtcattaca ggagcaaaag caccgattgc cttaacaagc agagcggact ctgctgaaaa
    20221 taaactgtat tccattgcgc tggcaatatg cgcatctgaa gaatacacac attaggagga
    20281 acgaacatgg aactttttaa atatatggag aaatacgatt acgaacaatt ggtattctgc
    20341 caggatgaac aatctggatt aaaagcgatt atcgccattc atgatacaac gcttggtccg
    20401 gcgcttggcg gaacgagaat gtggacatat gaaaatgaag aagcggcaat tgaagatgcg
    20461 ctcagattgg ctagaggcat gacctataag aacgcggcgg ccggcttaaa ccttggcggc
    20521 ggaaaaacag tcattatcgg cgatccgcgc aaagacaaaa atgaagaaat gttccgcgcg
    20581 tttggccgct atattcaagg gctgaacggc agatacatca cggctgaaga tgtgggcaca
    20641 acggtcgagg atatggatat cattcatgat gagacagact atgtcacagg gatttctcct
    20701 gctttcggct cttctggaaa tccgtcccca gtcacagcgt acggggtgta cagaggaatg
    20761 aaggcagcag ctaaagctgc ttttggaacc gactctcttg aaggaaaaac cattgctgta
    20821 cagggtgttg ggaacgtagc ctataacctt tgccgccacc tgcatgaaga aggagcaaac
    20881 ttaatcgtta cggatatcaa caaacaatct gtacagcgtg cagttgaaga ttttggcgcc
    20941 cgtgctgtag atcctgatga catttattca caagactgcg atatttatgc gccgtgtgcc
    21001 cttggtgcga ctattaacga cgacaccatt aaacagctga aggcgaaagt gatcgcaggt
    21061 gcggctaaca accaattaaa agagacacgc catggtgatc aaattcacga aatgggcatc
    21121 gtttatgcac cggattacgt gattaacgcg ggcggtgtta tcaacgtggc agatgagctt
    21181 tacggctata atgcagaacg tgcattgaaa aaagttgaag gcatttacgg caatatcgag
    21241 cgtgtactag agatttctca gcgtgacggc attcctgcat atttagcggc tgaccgcttg
    21301 gcagaggaac gaattgaacg catgcgccgc tcaagaagcc agtttttgca aaacggccac
    21361 agtgtattaa gcagacgtta agaaattgat ctggaggtta tgaaagtgct acatgacgaa
    21421 aaacgcattc tcacaattaa tccaggctca acttcaacga aaatcggtgt ttttcataac
    21481 gaaagaagca tttttgaaaa aacattgaga cacaacatag aagagctgca gcgatttgac
    21541 cgaattattg atcagtatga atttcgtaaa aaccatattc tcgaaacgct tcatgaacag
    21601 ggaatcaata tctcaaagtt tgatgcagtc tgcgcaagag gcggccttct ccggccaatt
    21661 gaaggcggga cctacgtggt gaatgatgag atgattgagg atttgaaaag cggctacgcc
    21721 ggtcagcatg cttctaatct cggcggcatt atcgcgcggg aaatcgctga tggcctgaat
    21781 atcccttcgt atatcgtcga ccctgttgtc gtagacgaaa tgtcagtgct tgcgaaagtt
    21841 tcaggcatgc ctgaaattga acggaaaagc attttccatg cgttaaacca aaaagctgtc
    21901 gctcgtaaag cggcagcctc tcttggcaaa cgatatgaga acatgaaaat gattattacc
    21961 catatgggcg gaggtattac aattggcgtc catgaccgcg ggcgagtggt agatgtcaat
    22021 aacggcctgc acggcgaggg gccattcagt cctgaacgag caggaacagt gcctgcggga
    22081 gatcttgttg atctatgttt ttcaggggaa tatacaaaag aagaaatcat gaaaaagctt
    22141 gttggcaccg gcggactttt aggctatctc ggtacaaatg atgcagtaaa agtagaacag
    22201 atgattcaag ggggcgatga aaaagcccgc ttcatttatg atgccatggc atatcaggta
    22261 gcaaaggaaa tcggggcagc cagcgcggcg ttaaaaggcg aagttgaagc gattgtgctg
    22321 acgggaggcc ttgcgtacgg caaaagcttt gtttctgcta tcagatcata catagattgg
    22381 atttcagacg ttttagtcta tccgggtgaa aatgaactgc agtctcttgc ccaaggggcg
    22441 ctcagagtat tgcagggcga agagcaatcc aaacaatatc gtattgaata gacagacagg
    22501 agtgagtcac catggcaact gagtatgacg tagtcattct gggcggcggt accggcggtt
    22561 atgttgcggc catcagagcc gctcagctcg gcttaaaaac agccgttgtg gaaaaggaaa
    22621 aactcggagg aacatgtctg cataaaggct gtatcccgag taaagcgctg cttagaagcg
    22681 cagaggtata ccggacagct cgtgaagccg atcaattcgg ggtggaaacg gctggcgtgt
    22741 ccctcaactt tgaaaaagtg cagcagcgta agcaagccgt tgttgataag cttgaagcgg
    22801 gtgtaaatca tttaatgaaa aaaggaaaaa ttgacgtgta caccggatat ggacgtatcc
    22861 ttggaccgtc aatcttctct ccgctgccgg gaacaatttc tgttgagcgg ggaaatggcg
    22921 aagaaaatga catgctgatc ccgaaacaag tgatcattgc aacaggatca agaccgagaa
    22981 tgcttccggg tcttgaagcg gatggtaagt ctgtactgac ttcagatgag gcgctccaaa
    23041 tggaggagct gccacaatca atcatcattg tcggcggagg agttatcggt atcgaatggg
    23101 cgtctatgct tcatgatttt ggtgtgaagg taacggttat tgaatacgcg gatcgcatat
    23161 tgccgactga agatctagag atttcaaaag aaatggaaag tcttcttaag aaaaaaggca
    23221 tccagttcat aacagg
//
