LOCUS       gnlProkkaLCIAKKDL_457   4557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCIAKKDL_457.
ACCESSION   gnlProkkaLCIAKKDL_457
VERSION     gnlProkkaLCIAKKDL_457
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 13:09:55
            Original ID  :: gnl|Prokka|LCIAKKDL_457
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4557
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4557
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[91:442]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      92..442
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..4557
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4557
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(92..442)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg452_1"
                     /sec_met_domain="PqqD_RRE (E-value: 4.5e-12, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(540..1928)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg452_2"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(2176..2571)
                     /locus_tag="ctg452_3"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(2594..3355)
                     /locus_tag="ctg452_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKXXXXKKCLLCRPNQIFGEIDY"
     CDS             complement(3361..3888)
                     /locus_tag="ctg452_5"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(3875..4489)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 82.4; E-value:
                     5.2e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg452_6"
                     /transl_table=11
                     /translation="MPAIQLTEDAKKELLAYPWPGNVRQLKNITEQISIIETNREISAA
                     ILQNYLPAQNTQRLPALMGTRESKGFESEREILYSVLFDMRQEVAELKKMVHNLMAERA
                     GQVGQVGQMGTVVTTPVVTAHQPSVPAIIHTMQPTVCKDDDDIQDTEEYVEESPLSLDE
                     VEKEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEYELD"
ORIGIN
        1 ccgtttaact tctttaactg ttttttatag gcctattatt tgcataggtc ttagaattcc
       61 gtggcctctg tggtgaaata taaattccta tttatgcgac tggtatcacc agttttataa
      121 atccatcttt ctgcatttga gaaagataag ccgatacacg cgactcgtag ccctcttcat
      181 tttgaaaatg gtctgcgagt ttttctataa tctcacgaac attgcgtttt ccatctatca
      241 gttcccatac agccgtaccg tgttcttcca atttcacatg aagttctttc gacattcctt
      301 tcggcacaag gaagcgttgc atccacggat atttaaaacg gggaaaggag agcacaattg
      361 tctccccttc cctttctgct gtaatatgtt cactgcgaca gggaatgacc tctaacaggt
      421 tgattttctc tttggcagcc atacttctta ttttttattt cagagtattc atactgatac
      481 ccttttgttt acaccttgat acaaaattcc tttgttactt taggtattga atttcccagt
      541 tacttttgga tattcgcctc ttccagaccg tatcccttct tcttgttctc tgccttcaac
      601 atcaaagcca caatcagagc aagtacacca aagagagcaa aaatagtcat cggcaacgtg
      661 tagtcataag tctgtgcacc gtctactacc ggacctttgc aataagtatt caacacccat
      721 ccgatcaaca aaggaacacc catcaatccc cagttctgta cccagaaaat caatgcgtat
      781 gcggtaccca actgtttttc cggaataatc ttcggaacag acggccacat agctgaaggc
      841 accaacgaga aggcaaatcc caatataatc atgatgatag tagcaaacca ccatatattc
      901 agtataggca gagcaaacat cgtatgcaca aaaataagca tcactgatcc gattatcatc
      961 aatgtggctc ccttaccgat acggtcataa agcgaaccga acaacggagt caggataatc
     1021 gcaccaatcg gcaacaatcc gggaatcgtt cccgccaact tcggatctac gttatatttc
     1081 tgcaccatca agtcggcagc atacttgata aaggggaata cagccgagta gaacaataca
     1141 catagtaatg caatcaacca gaatccttta ttggtaataa tatacacaat atctttcata
     1201 cggaacggtt cttccggttc caatccctct gcatccaaag aagcatccaa cttcttatca
     1261 tagaaagtat aaaggaaaaa agcaatcgta cccacgcaca acataatcag acaaaacaaa
     1321 atcggagcag gaatatttgt atggaatgtg ccactctcat ccgtagatcc gaaaaagtct
     1381 gccaaaggaa ctgtcaatac catcgccaga gttgttccga tacgtgccgt agccatttca
     1441 agtcccatag ccaatgccat ttccttgccc ttgaaccatt tcactataat cttggaaaca
     1501 gtgataccag caatctccac acctacacca aagatagcat atcccaatgc agccaacgtc
     1561 acctgtgttt tgaatccgaa gagcatggca ccttccggaa aagtagtaga aatcgcatag
     1621 tatttcaatc cacaaccaaa caccatcaat aagcaagccc ccattccggt gaaacgaact
     1681 cccatcttat ccaaaatgat accaccgaag atcagcatca ataggaatac attaaaccac
     1741 ccgtaagcac ttgtgaagaa accataatca agactgtccc atagtagttc tttctcaagc
     1801 atgggtttta gaggagacat tacgtcggtg aggaaatagc cgcatagcat agtaaatgcg
     1861 accaatgcta gaacactcca tcggagtacg gcggagtcat tcaatttctg tttcaaatgt
     1921 tctgtcattg ttatatttaa aaaagtagtt aataatctta tacagccaac aaaggtagtt
     1981 aaatctcgtt tgtttctatc acaaagagat tgtttttaca agaaaaagtt aagtgcggat
     2041 tacactgacc acgcggaaca ttgaaaatcc gtgtaatctg cgtaatccgc acttaaatat
     2101 caaagaaatg cagcatccgt ctgcaccttc ccattaatgg ttttacccca aagtcttact
     2161 tgacgacgga gtgaattact ctgctgcagg agcaggagtt tcagtagccg gtgccggagt
     2221 ttctgtagca ggtgcattgg tagcaggagc ttcagtttgc ggcgcagccg tacctgcggg
     2281 taagttatac gggttagtct gttgttcttt ctgtgcctgt tccaacactg cgtctttagc
     2341 aacagcagag cgaggaacta cataagcagt agcaatgctc attacaacca taaagatggc
     2401 caggccccat gttgcttttt ccagaaagtc tgtagtcttg cgcacgccca tgatggcgtt
     2461 agatgaagag aaaccagaag caagtccgcc tccttttgag ttctgaatca gcacgatgaa
     2521 acacatcaac aaggctgcaa taaccattaa gataacgaat aataagtaca tttttagtta
     2581 ttttgaatta gcgttaataa tcaatttctc caaaaatctg atttggtctg caaagtaagc
     2641 attttttttn nnnnnnnnnt ttcaagctta attttttaat tatttcaaga gcttttgaat
     2701 atcgttgctg tttaacatag atttttgcca aagtttccgt aaaacagctg tcatcttcct
     2761 cttcttcctt tatcgtttct tcttcggtaa gttcgtccga agaggttggc gaagatggca
     2821 tttcttctct taaaggtttc atgcagaggg gagagtcgct ctcgctcttt tctataaaat
     2881 cgtcaatcag ttcgaagcct ttgagtttgg gcgtttcttc agccggctgt tccgtggccg
     2941 gagtctcctc caaaaggaaa gaggtgtaat ccatcgaata gtcgaaactg gtccgggcag
     3001 tcacctcttc gggtactgtg gacaagaaag cgtcgatcaa tgctaatgtg cggtctacgg
     3061 acggttcgtc tttcagcacc tccgtgagag gtactccctt tttccgtgcc tgcacatcat
     3121 agcggtcacc ttcaatcaac cggaacaact gccgtctgtc tgcaatgtaa agaactgctt
     3181 tccgcagttc tccaccgaaa ctaatatcat ggagaatata cagattcttc agatacaaca
     3241 gacgaagtga ctgaaaatac ggatacctcg caagaagatt gcgcagttcg tacaaagtat
     3301 ccctattcag cgtctcggga tgctgaatcc attgttgaaa gttaacagaa gtcatttata
     3361 ttaccagttt gctacagttg cattaaaaat ttggtcggtg atctctttag acatttcagc
     3421 aatcaatccg tcctgtacgg cagtcaacaa ctgggtagag tcgtaggtac ggaacgcaga
     3481 aaactgttgt tcaaagtctt cggcatgatt ggtgttgttg acaaaacgca cattgacggt
     3541 gatagtcaac ttcgtctccg aagaataacc gtcggcagat actgcctggt tgtactgatt
     3601 gtaccctgtg atttctccgt caatctgcaa gtcggcattt tgactcggct tgagcagttg
     3661 cagacgggtc tgccggatga agatatcttt caggtcctca ttgaatttgg ttgccaacgg
     3721 agcatataca tactccgact tgatcgggaa gtcggctatc gaaatggtct ttaccttatc
     3781 ataattgata gacgatccgt taaacttata ggaaacagtg cacgcaatga ctaccaacgg
     3841 caagccgaac agtagcaaag ggcgtattat tttcttaatc caattcatat tcttttattt
     3901 ttctataaag tgtacgctcg gaaatattca agtccttggc cgcactcttc cgctttccat
     3961 gatgcctctc aagtgccttg cgtatcattt ctttctccac ttcgtccagt gacaaaggag
     4021 attcttctac atattcttcc gtgtcttgta tgtcatcgtc atccttgcaa accgtaggct
     4081 gcatggtgtg aatgatagca ggtaccgaag gttgatgcgc cgtcactacc ggagtagtaa
     4141 ccaccgttcc catttgccct acctgcccca cctgtccggc acgttccgcc atcaggttgt
     4201 gcaccatctt cttcagctcc gccacttcct ggcgcatatc gaacagaaca gaataaagaa
     4261 tctcccgttc gctctcaaag cctttactct cacgcgttcc catcagcgcg ggaagacgtt
     4321 gcgtattttg tgcaggaaga taattctgca agatagcagc agagatctcc ctgttggttt
     4381 caatgataga tatttgctcg gtgatgttct tcaactgacg aacgttgccg ggccacgggt
     4441 aagccaataa ctctttcttc gcatcctccg tcaactggat agcaggcatc cggtatttct
     4501 ctgcaactgt ctcttataca catctccgag cccacgagac tatcccacat ctcgtat
//
